Michael J. Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides
Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael J., 15 Feb 2006, In: Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Ethnic differences in the prevalence and recognition of depression in a primary care population with and without type 2 diabetes
Ali, S., Taub, N. A., Stone, M. A., Davies, Michael J., Skinner, Timothy & Khunti, K., 1 Sep 2010, Diabetologia.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
The association between depression and health-related quality of life in people with type 2 diabetes: A systematic literature review
Ali, S., Stone, M., Skinner, Timothy, Robertson, N., Davies, Michael J. & Khunti, K., 1 Feb 2010, In: Diabetes/Metabolism Research and Reviews. 26, 2, p. 75-89 15 p.Research output: Contribution to journal › Review › peer-review
Chemical modification of lysozyme, glucose 6-phosphate dehydrogenase, and bovine eye lens proteins induced by peroxyl radicals: role of oxidizable amino acid residues
Arenas, A., López-Alarcón, C., Kogan, M., Lissi, E., Davies, Michael J. & Silva, E., 18 Jan 2013, In: Chemical Research in Toxicology. 26, 1, p. 67-77 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The association between anxiety and measures of glycaemia in a population-based diabetes screening programme
Aujla, N., Davies, Michael J., Skinner, Timothy, Gray, L. J., Webb, D. R., Srinivasan, B. & Khunti, K., 1 Jul 2011, In: Diabetic Medicine. 28, 7, p. 785-788 4 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The prevalence of depressive symptoms in a white European and South Asian population with impaired glucose regulation and screen-detected Type 2 diabetes mellitus: A comparison of two screening tools
Aujla, N., Skinner, Timothy, Khunti, K. & Davies, Michael J., 1 Aug 2010, In: Diabetic Medicine. 27, 8, p. 896-905 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The prevalence of depression in White-European and South-Asian people with impaired glucose regulation and screen-detected type 2 diabetes mellitus
Aujla, N., Abrams, K. R., Davies, Michael J., Taub, N., Skinner, Timothy & Khunti, K., 9 Nov 2009, In: PLoS ONE. 4, 11, e7755.Research output: Contribution to journal › Journal article › peer-review
- Published
3-Hydroxykynurenine bound to eye lens proteins induces oxidative modifications in crystalline proteins through a type I photosensitizing mechanism
Avila, F., Ravello, N., Zanocco, A. L., Gamon, Luke Francis, Davies, Michael J. & Silva, E., 2019, In: Free Radical Biology and Medicine. 141, p. 103-114Research output: Contribution to journal › Journal article › peer-review
Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates
Barrett, T. J., Pattison, D. I., Leonard, S. E., Carroll, K. S., Davies, Michael J. & Hawkins, Clare Louise, 15 Mar 2012, In: Free Radical Biology & Medicine. 52, 6, p. 1075-85 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Roles of tyrosine-rich precursor glycoproteins and dityrosine- and 3,4-dihydroxyphenylalanine-mediated protein cross-linking in development of the oocyst wall in the coccidian parasite Eimeria maxima
Belli, S. I., Wallach, M. G., Luxford, C., Davies, Michael J. & Smith, N. C., Jun 2003, In: Eukaryotic Cell (Online Edition). 2, 3, p. 456-64 9 p.Research output: Contribution to journal › Journal article › peer-review
Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers
Birinyi-Strachan, L. C., Davies, Michael J., Lewis, R. J. & Nicholson, G. M., Oct 2005, In: Neuropharmacology. 49, 5, p. 669-86 18 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Photobiocatalysis by a Lytic Polysaccharide Monooxygenase Using Intermittent Illumination
Blossom, B. M., Russo, D. A., Singh, R. K., Van Oort, B., Keller, M. B., Simonsen, Tor Ivan, Perzon, A., Gamon, Luke Francis, Davies, Michael J., Cannella, D., Croce, R., Jensen, Poul Erik, Bjerrum, Morten Jannik & Felby, C., 2020, In: ACS Sustainable Chemistry & Engineering. 8, 25, p. 9301-9310 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Aryl Fluorosulfate Based Inhibitors That Covalently Target the SIRT5 Lysine Deacylase**
Bolding, J. E., Martín-Gago, P., Rajabi, N., Gamon, Luke Francis, Hansen, Tobias Nørby, Bartling, Christian Reinhard Otto, Strømgaard, Kristian, Davies, Michael J. & Olsen, Christian Adam, 2022, In: Angewandte Chemie - International Edition. 61, 47, 11 p., e202204565.Research output: Contribution to journal › Journal article › peer-review
Tryptophan oxidation in proteins exposed to thiocyanate-derived oxidants
Bonifay, V., Barrett, T. J., Pattison, D. I., Davies, Michael J., Hawkins, Clare Louise & Ashby, M. T., 15 Dec 2014, In: Archives of Biochemistry and Biophysics. 564, p. 1-11 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives
Borges, E. L., Ignasiak, M. T., Velichenko, Y., Perin, G., Hutton, C. A., Davies, Michael J. & Schiesser, C. H., 25 Mar 2018, In: Chemical Communications. 54, 24, p. 2990-2993Research output: Contribution to journal › Journal article › peer-review
- Published
Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells
Brown, B. E., Dean, R. T. & Davies, Michael J., Feb 2005, In: Diabetologia. 48, 2, p. 361-9 9 p.Research output: Contribution to journal › Journal article › peer-review
Supplementation with carnosine decreases plasma triglycerides and modulates atherosclerotic plaque composition in diabetic apo E(-/-) mice
Brown, B. E., Kim, C. H. J., Torpy, F. R., Bursill, C. A., McRobb, L. S., Heather, A. K., Davies, Michael J. & van Reyk, D. M., Feb 2014, In: Atherosclerosis. 232, 2, p. 403-9 7 p.Research output: Contribution to journal › Journal article › peer-review
Apolipoprotein A-I glycation by glucose and reactive aldehydes alters phospholipid affinity but not cholesterol export from lipid-laden macrophages
Brown, B. E., Nobecourt, E., Zeng, J., Jenkins, A. J., Rye, K. & Davies, Michael J., 2013, In: PLOS ONE. 8, 5, p. e65430Research output: Contribution to journal › Journal article › peer-review
Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages
Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael J., Mar 2007, In: F E B S Journal. 274, 6, p. 1530-41 12 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Modification of the extracellular matrix of the arterial wall by myeloperoxidase contributes to atherosclerosis: [Meeting Absract]
Cai, H., Chuang, Christine & Davies, Michael J., 2018, In: International Journal of Experimental Pathology. 99, 6, p. A24-A24Research output: Contribution to journal › Conference abstract in journal › peer-review
- Published
Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells
Cai, H., Chuang, Christine, Vanichkitrungruang, S., Hawkins, Clare Louise & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 134, p. 526-536Research output: Contribution to journal › Journal article › peer-review
- Published
Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification
Cai, H., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2020, In: Scientific Reports. 13 p., 666.Research output: Contribution to journal › Journal article › peer-review
- Published
Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation
Campolo, N., Mastrogiovanni, M., Mariotti, M., Issoglio, F. M., Estrin, D., Hägglund, Per Mårten, Grune, T., Davies, Michael J., Bartesaghi, S. & Radi, R., 2023, In: Journal of Biological Chemistry. 299, 3, 22 p., 102941.Research output: Contribution to journal › Journal article › peer-review
Increasing capacity to deliver diabetes self-management education: Results of the DESMOND lay educator non-randomized controlled equivalence trial
Carey, M. E., Mandalia, P. K., Daly, H., Gray, L. J., Hale, R., Martin Stacey, L., Taub, N., Skinner, Timothy, Stone, M., Heller, S., Khunti, K. & Davies, Michael J., 1 Jan 2014, In: Diabetic Medicine. 31, 11, p. 1431-1438 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Reaction of low-molecular-mass organoselenium compounds (and their sulphur analogues) with inflammation-associated oxidants
Carroll, L., Davies, Michael J. & Pattison, D. I., 2015, In: Free Radical Research. 49, 6, p. 750-767 18 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Formation and detection of oxidant-generated tryptophan dimers in peptides and proteins
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael J., Dec 2017, In: Free Radical Biology & Medicine. 113, p. 132-142 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael J. & Hawkins, Clare Louise, 2017, In: Redox Biology. 12, p. 872-882 12 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Interaction kinetics of selenium -containing compounds with oxidants
Carroll, L., Gardiner, K., Ignasiak, M., Holmehave, J., Shimodaira, S., Breitenbach, T., Iwaoka, M., Ogilby, P. R., Pattison, David & Davies, Michael J., 2020, In: Free Radical Biology and Medicine. 155, p. 58-68Research output: Contribution to journal › Journal article › peer-review
- Published
Oxidant-induced glutathionylation at protein disulfide bonds
Carroll, L., Jiang, S., Irnstorfer, J., Beneyto, S., Ignasiak, M. T., Rasmussen, L. M., Rogowska-Wrzesinska, A. & Davies, Michael J., 20 Nov 2020, In: Free Radical Biology and Medicine. 160, p. 513-525 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Superoxide radicals react with peptide-derived tryptophan radicals with very high rate constants to give hydroperoxides as major products
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael J., Apr 2018, In: Free Radical Biology and Medicine. 118, p. 126-136Research output: Contribution to journal › Journal article › peer-review
- Published
Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage
Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael J. & Hawkins, Clare Louise, Jul 2015, In: Free Radical Biology & Medicine. 84, p. 279-288 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Carnosine and Carcinine Derivatives Rapidly React with Hypochlorous Acid to Form Chloramines and Dichloramines
Carroll, L., Karton, A., Radom, L., Davies, Michael J. & Pattison, D. I., 2019, In: Chemical Research in Toxicology. 32, 3, p. 513-525 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins
Casaril, A. M., Ignasiak, M. T., Chuang, Christine, Vieira, B., Padilha, N. B., Carroll, L., Lenardão, E. J., Savegnago, L. & Davies, Michael J., Dec 2017, In: Free Radical Biology & Medicine. 113, p. 395-405 11 p.Research output: Contribution to journal › Journal article › peer-review
Hypobromous acid and bromamine production by neutrophils and modulation by superoxide
Chapman, A. L. P., Skaff, O., Senthilmohan, R., Kettle, A. J. & Davies, Michael J., 1 Feb 2009, In: Biochemical Journal. 417, 3, p. 773-81 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The Use of Membrane Filtration to Increase Native Whey Proteins in Infant Formula
Chen, Y., Callanan, M., Shanahan, C., Tobin, J., Gamon, Luke Francis, Davies, Michael J., Giblin, L. & Brodkorb, A., Sep 2021, In: Dairy. 2, 4, p. 515-529Research output: Contribution to journal › Journal article › peer-review
- Published
Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models
Chen, Z., Kondrashina, A., Greco, I., Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael J., 2019, In: Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646Research output: Contribution to journal › Journal article › peer-review
- Published
Characterisation and quantification of protein oxidative modifications and amino acid racemisation in powdered infant milk formula
Chen, Z., Leinisch, F., Greco, I., Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael J., 2019, In: Free Radical Research. 53, 1, p. 68-81Research output: Contribution to journal › Journal article › peer-review
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Characterization and quantification of protein oxidative modifications and amino acid racemization in powdered infant milk formula: [Meeting Abstract]
Chen, Z., Leinisch, F., Greco, I., Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, Supplement 1, p. S47 1 p., P-8.Research output: Contribution to journal › Conference abstract in journal
Oxidation and modification of extracellular matrix and its role in disease
Chuang, Christine, Degendorfer, G. & Davies, Michael J., Sep 2014, In: Free Radical Research. 48, 9, p. 970-89 20 p.Research output: Contribution to journal › Journal article › peer-review
Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells
Chuang, Christine, Degendorfer, G., Hammer, A., Whitelock, J. M., Malle, E. & Davies, Michael J., 15 Apr 2014, In: Biochemical Journal. 459, 2, p. 313-22 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Oxidant-modified amylin fibrils and aggregates alter the inflammatory profile of multiple myeloid cell types, but are non-toxic to islet β cells
Clemen, R., Fuentes Lemus, Eduardo, Bekeschus, S. & Davies, Michael J., 2023, In: Redox Biology. 65, 14 p., 102835.Research output: Contribution to journal › Journal article › peer-review
- Published
Novel monohydroxamate drugs attenuate myocardial reperfusion-induced arrhythmias
Collis, C. S., Rice-Evans, C. & Davies, Michael J., Apr 1996, In: International Journal of Biochemistry & Cell Biology. 28, 4, p. 405-13 9 p.Research output: Contribution to journal › Journal article › peer-review
Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells
Cook, N. L., Viola, H. M., Sharov, V. S., Hool, L. C., Schöneich, C. & Davies, Michael J., 1 Mar 2012, In: Free Radical Biology & Medicine. 52, 5, p. 951-61 11 p.Research output: Contribution to journal › Journal article › peer-review
Myeloperoxidase-derived oxidants rapidly oxidize and disrupt zinc-cysteine/histidine clusters in proteins
Cook, N. L., Pattison, D. I. & Davies, Michael J., 1 Dec 2012, In: Free Radical Biology & Medicine. 53, 11, p. 2072-80 9 p.Research output: Contribution to journal › Journal article › peer-review
Myeloperoxidase-Derived Oxidants Rapidly and Efficiently Oxidise Protein Zinc-Thiol Clusters
Cook, N. L., Pattison, David & Davies, Michael J., 2012, In: Free Radical Biology and Medicine. 53, Supl. 2, p. S146 1 p., 355.Research output: Contribution to journal › Conference abstract in journal
- Published
The myeloperoxidase-derived oxidant hypothiocyanous acid inhibits protein tyrosine phosphatases via oxidation of key cysteine residues
Cook, N. L., Moeke, C. H., Fantoni, L. I., Pattison, D. I. & Davies, Michael J., 1 Jan 2016, In: Free Radical Biology & Medicine. 90, p. 195-205 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
A hydrogen-donating monohydroxamate scavenges ferryl myoglobin radicals
Cooper, C. E., Green, E. S., Rice-Evans, C. A., Davies, Michael J. & Wrigglesworth, J. M., Apr 1994, In: Free Radical Research. 20, 4, p. 219-27 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: The Microalbuminuria Education and Medication Optimisation (MEMO) study
Crasto, W., Jarvis, J., Khunti, K., Skinner, Timothy, Gray, L. J., Brela, J., Troughton, J., Daly, H., Lawrence, I. G., McNally, P. G., Carey, M. E. & Davies, Michael J., 1 Sep 2011, In: Diabetes Research and Clinical Practice. 93, 3, p. 328-336 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Dityrosine, 3,4-dihydroxyphenylalanine (DOPA), and radical formation from tyrosine residues on milk proteins with globular and flexible structures as a result of riboflavin-mediated photo-oxidation
Dalsgaard, T. K., Nielsen, J. H., Brown, B. E., Stadler, N. & Davies, Michael J., 27 Jul 2011, In: Journal of Agricultural and Food Chemistry. 59, 14, p. 7939-47 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Anthocyanin complex niosome gel accelerates oral wound healing: In vitro and clinical studies
Damrongrungruang, T., Paphangkorakit, J., Limsitthichaikoon, S., Khampaenjiraroch, B., Davies, Michael J., Sungthong, B. & Priprem, A., 2021, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 37, 14 p., 102423.Research output: Contribution to journal › Journal article › peer-review
- Published
Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching
David Figueroa, J., Fuentes-Lemus, E., Dorta, E., Melin, V., Cortes-Rios, J., Faundez, M., Contreras, D., Denicola, A., Alvarez, B., Davies, Michael J. & Lopez-Alarcon, C., 2019, In: Redox Biology. 24, 9 p., 101207.Research output: Contribution to journal › Journal article › peer-review
- Published
Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial
Davies, Michael J., Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In: BMJ. 336, 7642, p. 491-495 5 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The DESMOND educational intervention
Davies, Michael J., Heller, S., Khunti, K. & Skinner, Timothy, 1 Mar 2008, In: Chronic Illness. 4, 1, p. 38-40 3 p.Research output: Contribution to journal › Comment/debate › peer-review
- Published
Adduction reactions of alpha,beta-unsaturated aldehydes to proteins
Davies, Michael J., 2022, In: Toxicology Letters. 368, Suppl, p. S62-S62 1 p.Research output: Contribution to journal › Conference abstract in journal › peer-review
- Published
Tempus fugit horizontal ellipsis
Davies, Michael J., 2019, In: Free Radical Research. 53, 1, p. 1-1Research output: Contribution to journal › Editorial › peer-review
- Published
"What, where and how much? Key challenges in protein oxidation"
Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 165, Suppl. 1, p. 15-15 Suppl. 13-1.Research output: Contribution to journal › Conference abstract in journal › peer-review
- Published
Myeloperoxidase: Mechanisms, reactions and inhibition as a therapeutic strategy in inflammatory diseases
Davies, Michael J., 2021, In: Pharmacology and Therapeutics. 218, 23 p., 107685.Research output: Contribution to journal › Review › peer-review
- Published
Reactivity of Peroxidase-Derived Oxidants with Proteins, Glycoproteins and Proteoglycans
Davies, Michael J., 1 Jan 2021, Mammalian Heme Peroxidases: Diverse Roles in Health and Disease. CRC Press, p. 53-77Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
1,4-Anhydro-4-seleno-d-talitol (SeTal): a remarkable selenium-containing therapeutic molecule
Davies, Michael J. & Schiesser, C. H., 2019, In: New Journal of Chemistry. 43, 25, p. 9759-9765Research output: Contribution to journal › Review › peer-review
- Published
Peroxides and protein oxidation
Davies, Michael J., 1 Jan 2017, Hydrogen Peroxide Metabolism in Health and Disease. CRC Press, p. 101-124Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Stable markers of oxidant damage to proteins and their application in the study of human disease
Davies, Michael J., Fu, S., Wang, H. & Dean, R. T., Dec 1999, In: Free Radical Biology & Medicine. 27, 11-12, p. 1151-63 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Protein oxidation and peroxidation
Davies, Michael J., 2016, In: Biochemical Journal. 473, 7, p. 805-825 21 p.Research output: Contribution to journal › Review › peer-review
- Published
Sulfur and selenium in oxidation protection
Davies, Michael J., 2015, In: La chimica e l’industria, Chimica & Materiali. 2015, 6, p. 50-54Research output: Contribution to journal › Review › peer-review
Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention
Davies, Michael J., Jan 2011, In: Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 8-19 12 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Photo-oxidation of proteins and its role in cataractogenesis
Davies, Michael J. & Truscott, R. J., 2001, In: Journal of Photochemistry and Photobiology, B: Biology. 63, 1-3, p. 114-25 12 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Reactive species formed on proteins exposed to singlet oxygen
Davies, Michael J., Jan 2004, In: Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The Role of Myeloperoxidase in Biomolecule Modification, Chronic Inflammation, and Disease
Davies, Michael J. & Hawkins, Clare Louise, 2020, In: Antioxidants & Redox Signaling. 32, 13, p. 957-981Research output: Contribution to journal › Review › peer-review
- Published
Protein and peptide alkoxyl radicals can give rise to C-terminal decarboxylation and backbone cleavage
Davies, Michael J., 1 Dec 1996, In: Archives of Biochemistry and Biophysics. 336, 1, p. 163-72 10 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Detection and characterisation of radicals using electron paramagnetic resonance (EPR) spin trapping and related methods
Davies, Michael J., 2016, In: Methods. 109, p. 21-30 10 p.Research output: Contribution to journal › Journal article › peer-review
The oxidative environment and protein damage
Davies, Michael J., 17 Jan 2005, In: B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.Research output: Contribution to journal › Journal article › peer-review
- Published
EPR spin trapping of protein radicals
Davies, Michael J. & Hawkins, Clare Louise, 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.Research output: Contribution to journal › Journal article › peer-review
Mammalian heme peroxidases: from molecular mechanisms to health implications
Davies, Michael J., Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In: Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates
Davies, Michael J. & Hawkins, C. L., Dec 2000, In: Free Radical Research. 33, 6, p. 719-29 11 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Singlet oxygen-mediated damage to proteins and its consequences
Davies, Michael J., 6 Jun 2003, In: Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.Research output: Contribution to journal › Journal article › peer-review
Free Radical Research origins
Davies, Michael J., Jan 2012, In: Free Radical Research. 46, 1, p. 1Research output: Contribution to journal › Journal article
- Published
Biochemistry and pathology of radical-mediated protein oxidation
Dean, R. T., Fu, S., Stocker, R. & Davies, Michael J., 1997, In: Biochemical Journal. 324 ( Pt 1), p. 1-18 18 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Peroxynitrite-mediated oxidation of plasma fibronectin
Degendorfer, G., Chuang, Christine, Kawasaki, H., Hammer, A., Malle, E., Yamakura, F. & Davies, Michael J., Aug 2016, In: Free Radical Biology & Medicine. 97, p. 602-615 14 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin
Degendorfer, G., Chuang, Christine, Hammer, A., Malle, E. & Davies, Michael J., Dec 2015, In: Free Radical Biology & Medicine. 89, p. 721-733 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function: [Meeting Abstract]
Degendorfer, G., Lorentzen, Lasse Gøbel, Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Haegglund, P., Malle, E., Wise, S. & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, S1, p. S102-S103 P-192 .Research output: Contribution to journal › Conference abstract in journal › peer-review
- Published
Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function
Degendorfer, G., Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Hägglund, Per Mårten, Malle, E., Wise, S. G. & Davies, Michael J., 1 Feb 2018, In: Free Radical Biology & Medicine. 115, S1, p. 202-214 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
The cysteine residue in beta-lactoglobulin reacts with oxidized tyrosine residues in beta-casein to give casein-lactoglobulin dimers
Doblas, L., Hägglund, Per Mårten, Fuentes Lemus, Eduardo & Davies, Michael J., 2023, In: Archives of Biochemistry and Biophysics. 733, 7 p., 109482.Research output: Contribution to journal › Journal article › peer-review
Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides
Dremina, E. S., Sharov, V. S., Davies, Michael J. & Schöneich, C., Oct 2007, In: Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.Research output: Contribution to journal › Journal article › peer-review
A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis
Dunn, L. L., Simpson, P. J. L., Prosser, H. C., Lecce, L., Yuen, G. S. C., Buckle, A., Sieveking, D. P., Vanags, L. Z., Lim, P. R., Chow, R. W. Y., Lam, Y. T., Clayton, Z., Bao, S., Davies, Michael J., Stadler, N., Celermajer, D. S., Stocker, R., Bursill, C. A., Cooke, J. P. & Ng, M. K. C., Feb 2014, In: Diabetes. 63, 2, p. 675-87 13 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Peroxyl radicals induce oxidative crosslinking of superoxide dismutase 1 through self-reaction of protein radicals [Meeting Abstract]
Escobar, E., Fuentes-Lemus, E., Figueroa, J. D., Fuentealba, D., Denicola, A., Alvarez, B., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S21-S21 53.Research output: Contribution to journal › Conference abstract in journal
- Published
The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function
Escobar-Álvarez, E., Leinisch, F., Araya, G., Monasterio, O., Lorentzen, Lasse Gøbel, Silva, E., Davies, Michael J. & López-Alarcón, C., Nov 2017, In: Free Radical Biology and Medicine. 112, p. 60-68 9 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Role of amino acid oxidation and protein unfolding in peroxyl radical and peroxynitrite-induced inactivation of glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides
Figueroa, J. D., Fuentes Lemus, Eduardo, Reyes, J. S., Loaiza, M., Aliaga, M. E., Fierro, A., Leinisch, F., Hägglund, Per Mårten, Davies, Michael J. & López-Alarcón, C., 2022, In: Free Radical Biology and Medicine. 190, p. 292-306Research output: Contribution to journal › Journal article › peer-review
- Published
Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion
Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael J. & López-Alarcón, C., 2020, In: RSC Advances. 10, 43, p. 25786-25800 15 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Impact of myeloperoxidase-derived oxidants on vascular smooth muscle cell damage and death in atherosclerosis {Meeting Abstract]
Flouda, K., Davies, Michael J. & Hawkins, C., 2019, In: Free Radical Biology and Medicine. 139, S1, p. S23-S24 64.Research output: Contribution to journal › Conference abstract in journal
- Published
Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues
Flouda, K., Gammelgaard, Bente, Davies, Michael J. & Hawkins, Clare Louise, May 2021, In: Redox Biology. 41, 101873.Research output: Contribution to journal › Journal article › peer-review
- Published
Role of myeloperoxidase-derived oxidants in the induction of vascular smooth muscle cell damage
Flouda, K., Mercer, J., Davies, Michael J. & Hawkins, Clare Louise, 2021, In: Free Radical Biology & Medicine. 166, p. 165-177Research output: Contribution to journal › Journal article › peer-review
- Published
Complexation of AAPH (2,2′-azobis(2-methylpropionamidine) dihydrochloride) with cucurbit[7]uril enhances the yield of AAPH-derived radicals
Forero-Girón, A. C., Fuentealba, D., Mariño-Ocampo, N., Gutiérrez-Oliva, S., Herrera, B., Toro-Labbé, A., Fuentes Lemus, Eduardo, Davies, Michael J., Aliaga, M. E. & López-Alarcón, C., 2023, In: Journal of Molecular Liquids. 389, 9 p., 122840.Research output: Contribution to journal › Journal article › peer-review
- Published
Protein cysteine oxidation in redox signaling: Caveats on sulfenic acid detection and quantification
Forman, H. J., Davies, Michael J., Krämer, A. C., Miotto, G., Zaccarin, M., Zhang, H. & Ursini, F., 1 Mar 2017, In: Archives of Biochemistry and Biophysics. 617, p. 26-37 12 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque
Fu, S., Davies, Michael J., Stocker, R. & Dean, R. T., 1 Aug 1998, In: Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.Research output: Contribution to journal › Journal article › peer-review
- Published
alpha- and beta-casein aggregation induced by riboflavin-sensitized photo-oxidation occurs via di-tyrosine cross-links and is oxygen concentration dependent
Fuentes-Lemus, E., Silva, E., Leinisch, F., Dorta, E., Lorentzen, Lasse Gøbel, Davies, Michael J. & Lopez-Alarcon, C., 1 Aug 2018, In: Food Chemistry. 256, p. 119-128Research output: Contribution to journal › Journal article › peer-review
- Published
Oxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals
Fuentes-Lemus, E., Dorta, E., Escobar, E., Aspee, A., Pino, E., Abasq, M. L., Speisky, H., Silva, E., Lissi, E., Davies, Michael J. & Lopez-Alarcon, C., 2016, In: RSC Advances. 6, 63, p. 57948-57955 8 p.Research output: Contribution to journal › Journal article › peer-review
- Published
Oxidative damage on proteins is enhanced in crowded environments
Fuentes Lemus, Eduardo, Gamon, Luke Francis, Lopez-Alarcon, C. & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. S31-S32Research output: Contribution to journal › Conference abstract in journal
- Published
High concentrations of casein proteins exacerbate radical chain reactions and increase the extent of oxidative damage
Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Food Hydrocolloids. 121, 16 p., 107060.Research output: Contribution to journal › Journal article › peer-review
- Published
Tryptophan and Cysteine residues mediate chain reactions and propagation of oxidative damage in concentrated casein solutions
Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 177, Suppl. 1, p. 562 1 p.Research output: Contribution to journal › Conference abstract in journal
- Published
Binding of rose bengal to lysozyme modulates photooxidation and cross-linking reactions involving tyrosine and tryptophan
Fuentes-Lemus, E., Mariotti, M., Hägglund, Per Mårten, Leinisch, F., Fierro, A., Silva, E., Lopez-Alarcon, C. & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 143, p. 375-386Research output: Contribution to journal › Journal article › peer-review
- Published
Aggregation of alpha- and beta- caseins induced by peroxyl radicals involves secondary reactions of carbonyl compounds as well as di-tyrosine and di-tryptophan formation
Fuentes-Lemus, E., Silva, E., Barrias, P., Aspee, A., Escobar, E., Lorentzen, Lasse Gøbel, Carroll, L., Leinisch, F., Davies, Michael J. & Lopez-Alarcon, C., 20 Aug 2018, In: Free Radical Biology and Medicine. 124, p. 176-188Research output: Contribution to journal › Journal article › peer-review
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Protein oxidation and peroxidation
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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