Synthesis and antioxidant capacity of novel stable 5-tellurofuranose derivatives

Research output: Contribution to journalJournal articleResearchpeer-review

  • Elton L. Borges
  • Marta T. Ignasiak
  • Yuliia Velichenko
  • Gelson Perin
  • Craig A. Hutton
  • Davies, Michael J.
  • Carl H. Schiesser
Novel stable tellurium-containing carbohydrate derivatives are prepared from hexitols and pentitols through a double nucleophilic substitution with NaHTe in PEG-400. These tellurosugars react at very high rates with two-electron oxidants, including hypochlorous and peroxynitrous acid, formed at sites of inflammation, and show considerable promise as protective agents against oxidative damage.
Original languageEnglish
JournalChemical Communications
Issue number24
Pages (from-to)2990-2993
Publication statusPublished - 25 Mar 2018

ID: 210610293