Christina Christoffersen
Associate Professor
Physiology of circulation, kidney and lung
Blegdamsvej 3
2200 København N.
- Published
Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice: [Meeting Abstract]
Zacharias, T., Flouda, K., Jepps, T., Christoffersen, Christina, Pedersen, T., Gammelgaard, Bente, Schiesser, C. & Davies, Michael J., 20 May 2018, In: Free Radical Biology & Medicine. 120, S1, p. S68-S68 P-79.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Apolipoprotein M and its impact on endothelial dysfunction and inflammation in the cardiovascular system
Yao Mattisson, I. & Christoffersen, Christina, 2021, In: Atherosclerosis. 334, p. 76-84Research output: Contribution to journal › Review › Research › peer-review
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Effect of menopause and exercise training on plasma apolipoprotein M and sphingosine-1-phosphate
Yafasova, A., djc739, djc739, Egelund, J., Nyberg, M. P., Stallknecht, Bente Merete, Hellsten, Ylva, Nielsen, L. B. & Christoffersen, Christina, 2019, In: Journal of Applied Physiology. 126, 1, p. 214-220 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions
Wang, S., Mao, Y., Narimatsu, Y., Ye, Z., Tian, W., Goth, C. K., Lira-Navarrete, E., Pedersen, N. B., Benito-Vicente, A., Martin, C., Uribe, K. B., Hurtado-Guerrero, R., Christoffersen, C., Seidah, N. G., Nielsen, R., Christensen, E. I., Hansen, L., Bennett, E. P., Vakhrushev, S. Y., Schjoldager, K. T. & 1 others, , 2018, In: The Journal of Biological Chemistry. 293, 19, p. 7408 –7422Research output: Contribution to journal › Journal article › Research › peer-review
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Familial hypercholesterolaemia: cholesterol efflux and coronary disease
Versmissen, J., Vongpromek, R., Yahya, R., van der Net, J. B., van Vark-van der Zee, L., Blommesteijn-Touw, J., Wattimena, D., Rietveld, T., Pullinger, C. R., Christoffersen, Christina, Dahlbäck, B., Kane, J. P., Mulder, M. & Sijbrands, E. J. G., Jul 2016, In: European Journal of Clinical Investigation. 46, 7, p. 643-50 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein
Velagapudi, S., Rohrer, L., Poti, F., Feuerborn, R., Perisa, D., Wang, D., Panteloglou, G., Potapenko, A., Yalcinkaya, M., Hulsmeier, A. J., Hesse, B., Lukasz, A., Liu, M., Parks, J. S., Christoffersen, Christina, Stoffel, M., Simoni, M., Nofer, J. & von Eckardstein, A., 2021, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 41, 10, p. E468-E479 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding
Tian, E., Wang, S., Zhang, L., Zhang, Y., Malicdan, M. C., Mao, Y., Christoffersen, Christina, Tabak, L. A., Schjoldager, Katrine Ter-Borch Gram & Ten Hagen, K. G., 10 Dec 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 50, p. 25196-25202Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of insulin on natriuretic peptide gene expression in porcine heart
Terzic, D., Zois, N. E., Hunter, I., Christoffersen, Christina, Plomgaard, Peter Stendahl, Olsen, Lisbeth Høier, Jørgensen, Stine Ringholm, Pilegaard, Henriette & Goetze, Jens P. , 2020, In: Peptides. 131, 10 p., 170370.Research output: Contribution to journal › Journal article › Research › peer-review
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Subclinical atherosclerosis in patients with cyanotic congenital heart disease
Tarp, J. B., Sorgaard, M. H., Christoffersen, Christina, Jensen, A. S., Sillesen, Henrik, Celermajer, D., Eriksson, P., Estensen, M., Nagy, E., von Holstein-Rathlou, Niels-Henrik, Engstrøm, Thomas & Søndergaard, Lars, 2019, In: International Journal of Cardiology. 277, p. 97-103Research output: Contribution to journal › Journal article › Research › peer-review
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Vascular function in adults with cyanotic congenital heart disease
Tarp, J. B., Clausen, P., Celermajer, D., Christoffersen, Christina, Jensen, A. S., Sorensen, K., Sillesen, Henrik, Estensen, M., Nagy, E., von Holstein-Rathlou, Niels-Henrik, Engstrøm, Thomas, Feldt-Rasmussen, Bo & Søndergaard, Lars, 2020, In: IJC Heart and Vasculature. 30, 7 p., 100632.Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein M in patients with chronic kidney disease
Sørensen, I. M., Bertelsen, M., Freese, E., Lindhard, K., Ullum, H., Feldt-Rasmussen, Bo, Nielsen, L. B., Christoffersen, Christina & Bro, S., 2018, In: Atherosclerosis. 275, p. 304-311Research output: Contribution to journal › Journal article › Research › peer-review
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The metabolic signature of cardiovascular disease and arterial calcification in patients with chronic kidney disease
Sørensen, I. M., Bisgaard, Line, Bjergfelt, S. S., Ballegaard, E. L., Biering-Sørensen, Tor, Landler, N. E., Pedersen, T. X., Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Bro, S. & Christoffersen, Christina, 2022, In: Atherosclerosis. 350, p. 109-118 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Super-Resolution Ultrasound Imaging Provides Quantification of the Renal Cortical and Medullary Vasculature in Obese Zucker Rats: A Pilot Study
Søgaard, S. B., Andersen, S. B., Taghavi, I., Hoyos, C. A. V., Christoffersen, Christina, Hansen, Kristoffer Lindskov, Jensen, J. A., Nielsen, Michael Bachmann & Sorensen, Charlotte Mehlin, Jul 2022, In: Diagnostics. 12, 7, 1626.Research output: Contribution to journal › Journal article › Research › peer-review
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Super-Resolution Ultrasound Imaging of Renal Vascular Alterations in Zucker Diabetic Fatty Rats during the Development of Diabetic Kidney Disease
Søgaard, S. B., Andersen, S. B., Taghavi, I., Schou, M., Christoffersen, Christina, Jacobsen, Jens Christian Brings, Kjer, H. M., Gundlach, C., McDermott, Amy, Jensen, J. A., Nielsen, Michael Bachmann & Sorensen, Charlotte Mehlin, 12 Oct 2023, In: Diagnostics. 13, 20, 3197.Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery of plasma proteins associated with ventricular fibrillation during first ST-elevation myocardial infarction via proteomics
Stampe, N. K., Ottenheijm, Maud Eline, Drici, L., Albrechtsen, Nicolai Jacob Wewer, Nielsen, A. B., Christoffersen, Christina, Warming, P. E., Engstrøm, Thomas, Winkel, B. G., Jabbari, R., Tfelt-Hansen, Jacob & Glinge, C., 2024, In: European Heart Journal: Acute Cardiovascular Care. 13, 3, p. 264–272Research output: Contribution to journal › Journal article › Research › peer-review
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Gestational Hypertension and High-Density Lipoprotein Function: An Explorative Study in Overweight/Obese Women of the DALI Cohort
Stadler, J. T., van Poppel, M. N. M., Christoffersen, Christina, Hill, D., Wadsack, C., Simmons, D., Desoye, G., Marsche, G. & DALI Core Investigator Grp, 2023, In: Antioxidants. 12, 1, 13 p., 68.Research output: Contribution to journal › Journal article › Research › peer-review
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Regional distribution and severity of arterial calcification in patients with chronic kidney disease stages 1-5: a cross-sectional study of the Copenhagen chronic kidney disease cohort
Sorensen, I. M. H., Saurbrey, S. A. K., Hjortkjaer, H. O., Brainin, P., Carlson, N., Ballegaard, E. L. F., Kamper, A., Christoffersen, Christina, Feldt-Rasmussen, Bo, Kofoed, Klaus Fuglsang & Bro, S., 2020, In: BMC Nephrology. 21, 1, 11 p., 534.Research output: Contribution to journal › Journal article › Research › peer-review
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Coronary and extra-coronary artery calcium scores as predictors of cardiovascular events and mortality in chronic kidney disease stages 1-5: a prospective cohort study
Sorensen, I. M. H., Bjergfelt, S. S., Hjortkjær, H. O., Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Christoffersen, Christina & Bro, S., 2023, In: Nephrology Dialysis Transplantation. 38, 5, p. 1227–1239 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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METABOLIC PROFILING AS A MARKER OF CARDIOVASCULAR DISEASE AND ARTERIAL CALCIFICATION IN THE COPENHAGEN CHRONIC KIDNEY DISEASE COHORT
Soerensen, I. M. H., Bisgaard, Line, Bjergfelt, S. S., Ballegaard, E. L. F., Biering-Sørensen, Tor, Landler, N. E., Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Bro, S. & Christoffersen, Christina, 2021, In: Nephrology Dialysis Transplantation. 36, Suppl. 1, 2 p., FC060.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Diurnal gene expression of lipolytic natriuretic peptide receptors in white adipose tissue
Smith, J., Fahrenkrug, J., Jørgensen, H. L., Christoffersen, Christina & Goetze, J. P., Dec 2015, In: Endocrine Connections. 4, 4, p. 206-214 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiac natriuretic peptide gene expression and plasma concentrations during the first 72 hours of life in piglets
Smith, J., Christoffersen, Christina, Nørgaard, L. M., Olsen, Lisbeth Høier, Vejlstrup, N. G., Andersen, C. B. & Gøtze, J. P., 2013, In: Endocrinology. 154, 5, p. 1864-1872 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs
Shim, J., Poulsen, C. B., Hagensen, M. K., Larsen, T., Heegaard, P. M. H., Christoffersen, Christina, Bolund, L., Schmidt, M., Liu, Y., Li, J., Li, R., Callesen, H., Bentzon, J. F. & Sørensen, C. B., 2017, In: JACC: Basic to Translational Science. 2, 5, p. 591-600 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association between plasma apolipoprotein M and cardiac autonomic neuropathy in type 1 diabetes
Safi, M., Borup, A., Stevns Hansen, C., Rossing, Peter, Thorsten Jensen, M. & Christoffersen, Christina, 2022, In: Diabetes Research and Clinical Practice. 189, 7 p., 109943.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiovascular prognostic value of echocardiography and N terminal pro B-type natriuretic peptide in type 1 diabetes: The Thousand and 1 Study
Rørth, R., Jørgensen, P. G., Andersen, H. U., Christoffersen, Christina, Goetze, Jens P. , Køber, Lars Valeur, Rossing, Peter & bqn654, bqn654, 2020, In: European Journal of Endocrinology. 182, 5, p. 481-488Research output: Contribution to journal › Journal article › Research › peer-review
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Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway
Ratner, C., He, Z., Grunddal, Kaare Villum, Skov, Louise Julie, Hartmann, Bolette, Zhang, F., Feuchtinger, A., Bjerregaard, Anette, Christoffersen, Christina, Tschöp, M. H., Finan, B., DiMarchi, R. D., Leinninger, G. M., Williams, K. W., Clemmensen, Christoffer & Holst, Birgitte, 2019, In: Diabetes. 68, 6, p. 1329-1340Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Osteopontin deficiency dampens the pro-atherogenic effect of uraemia
Pedersen, T. X., Madsen, M., Nielsen, N. M. J., Christoffersen, Christina, Vikeså, J., Bro, S., Hultgårdh-Nilsson, A. & Nielsen, L. B., 1 Jun 2013, In: Cardiovascular Research. 98, 3, p. 352-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of Atherosclerosis
Pedersen, A. A., Pedersen, T. X., Junker, N., Christoffersen, Christina, Bartels, Emil Daniel, Madsen, M., Nielsen, Carsten Haagen & Nielsen, L. B., Sep 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 9, p. 1782-1790 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Blood biomarkers improve the prediction of prevalent and incident severe chronic kidney disease
Nusinovici, S., Li, H., Chong, C., Yu, M., Sørensen, I. M. H., Bisgaard, Line, Christoffersen, Christina, Bro, S., Liu, S., Liu, J. J., Chi, L. S., Wong, T. Y., Tan, G. S. W., Cheng, C. Y. & Sabanayagam, C., 2024, (E-pub ahead of print) In: Journal of Nephrology.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma activin A rises with declining kidney function and is independently associated with mortality in patients with chronic kidney disease
Nordholm, A., Sørensen, I. M. H., Bjergfelt, S. S., Fuchs, A., Kofoed, Klaus Fuglsang, Landler, N. E., Biering-Sørensen, Tor, Carlson, N., Feldt-Rasmussen, Bo, Christoffersen, Christina & Bro, S., 2023, In: Clinical Kidney Journal. 16, 12, p. 2712-2720 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ApoM: gene regulation and effects on HDL metabolism
Nielsen, L. B., Christoffersen, Christina, Ahnström, J. & Dahlbäck, B., 2009, In: Trends in Endocrinology and Metabolism. 20, 2, p. 66-71 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sphingosine-1-Phosphate reduces ischemia/reperfusion injury by phosphorylating the gap junction protein Connexin43
Morel, S., Christoffersen, Christina, Axelsen, L. N., Montecucco, F., Rochemont, V., Frias, M. A., Mach, F., James, R. W., Naus, C. C., Chanson, M., Lampe, P. D., Nielsen, Morten Schak, Nielsen, L. B. & Kwak, B. R., 13 Jan 2016, In: Cardiovascular Research. 109, p. 385-396 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Arg82Cys Polymorphism of the Protein Nepmucin Implies a Role in HDL Metabolism
Metz, Sophia, Krarup, N. T., Bryrup, T., Støy, J., Andersson, E. A., Christoffersen, Christina, Neville, M. J., Christiansen, Malene Revsbech, Jonsson, Anna Elisabet, Witte, D. R., Kampmann, U., Nielsen, L. B., Jørgensen, Niklas Rye, Karpe, F., Grarup, Niels, Pedersen, Oluf Borbye, Kilpeläinen, Tuomas O. & Hansen, Torben, 2022, In: Journal of the Endocrine Society. 6, 5, 10 p., bvac034.Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein M-bound sphingosine-1-phosphate regulates blood-brain barrier paracellular permeability and transcytosis
Mathiesen Janiurek, M., Soylu-Kucharz, R., Christoffersen, Christina, Kucharz, Krzysztof & Lauritzen, Martin, 25 Nov 2019, In: eLife. 8, 22 p., e49405.Research output: Contribution to journal › Journal article › Research › peer-review
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Endothelial and lipoprotein lipases in human and mouse placenta
Lindegaard, M. L. S., Olivecrona, G., Christoffersen, Christina, Kratky, D., Hannibal, Jens, Petersen, B. L., Zechner, R., Damm, Peter & Nielsen, L. B., 1 Nov 2005, In: Journal of Lipid Research. 46, 11, p. 2339-46 8 p.Research output: Contribution to journal › Journal article › Research
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Endothelial and lipoprotein lipases in human and mouse placenta
Lindegaard, M. L. S., Olivecrona, G., Christoffersen, Christina, Kratky, D., Hannibal, Jens, Petersen, B. L., Zechner, R., Damm, Peter & Nielsen, L. B., Nov 2005, In: Journal of Lipid Research. 46, 11, p. 2339-46 8 p.Research output: Contribution to journal › Journal article › Research
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Associations Between Albuminuria, Estimated GFR and Cardiac Phenotype in a Cohort with Chronic Kidney Disease: The CPH-CKD ECHO Study
Landler, N. E., Olsen, F. J., Christensen, J., Bro, S., Feldt-Rasmussen, Bo, Hansen, Ditte, Kamper, A., Christoffersen, Christina, Ballegaard, E. L. F., Sørensen, I. M. H., Bjergfelt, S. S., Seidelin, E., Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2022, In: Journal of Cardiac Failure. 28, 11, p. 1615-1627 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Validity of biopsy-based drug effects in a diet-induced obese mouse model of biopsy-confirmed NASH
Kristiansen, M. N. B., Veidal, S. S., Christoffersen, Christina, Feigh, M., Vrang, N., Roth, J. D., Erickson, M., Adorini, L. & Jelsing, J., 2019, In: B M C Gastroenterology. 19, 1, 11 p., 228 .Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular Characterization of Microvesicular and Macrovesicular Steatosis Shows Widespread Differences in Metabolic Pathways
Kristiansen, M., Veidal, S. S., Christoffersen, Christina, Jelsing, J. & Rigbolt, K. T. G., 2019, In: Lipids. 54, 1, p. 109-115Research output: Contribution to journal › Journal article › Research › peer-review
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Endothelial-Specific Loss of Sphingosine-1-Phosphate Receptor 1 Increases Vascular Permeability and Exacerbates Bleomycin-induced Pulmonary Fibrosis
Knipe, R. S., Spinney, J. J., Abe, E. A., Probst, C. K., Franklin, A., Logue, A., Giacona, F., Drummond, M., Griffith, J., Brazee, P. L., Hariri, L. P., Montesi, S. B., Black, K. E., Hla, T., Kuo, A., Cartier, A., Engelbrecht, E., Christoffersen, C., Shea, B. S., Tager, A. M. & 1 others, , 2022, In: American Journal of Respiratory Cell and Molecular Biology. 66, 1, p. 38-52 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents
Khetarpal, S. A., Schjoldager, K. T., Christoffersen, C., Raghavan, A., Edmondson, A. C., Reutter, H. M., Ahmed, B., Ouazzani, R., Peloso, G. M., Vitali, C., Zhao, W., Somasundara, A. V. H., Millar, J. S., Park, Y., Fernando, G., Livanov, V., Choi, S., Noé, E., Patel, P., Ho, S. P. & 12 others, , 9 Aug 2016, In: Cell Metabolism. 24, 2, p. 234-245 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Study protocol: Long-term effect of the New Nordic Renal Diet on phosphorus and lipid homeostasis in patients with chronic kidney disease, stages 3 and 4: a randomised controlled trial
Hansen, N. M., Rix, M., Kamper, A., Feldt-Rasmussen, Bo, Christoffersen, Christina, Astrup, A. & Salomo, L., 2021, In: B M J Open. 11, 8, 7 p., e045754.Research output: Contribution to journal › Journal article › Research › peer-review
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Oral pre-treatment with thiocyanate (SCN-) protects against myocardial ischaemia-reperfusion injury in rats
Hall, L., Guo, C., Tandy, S., Broadhouse, K., Dona, A. C., Malle, E., Bartels, Emil Daniel, Christoffersen, Christina, Grieve, S. M., Figtree, G., Hawkins, Clare Louise & Davies, Michael J., 2021, In: Scientific Reports. 11, 1, 18 p., 12712.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased plasma apoM levels impair triglyceride turnover in mice
Hajny, Stefan, Borup, A., Elsoe, S. & Christoffersen, Christina, 2021, In: B B A - Molecular and Cell Biology of Lipids. 1866, 9, 9 p., 158969.Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein M and Risk of Type 2 Diabetes
Hajny, Stefan, Christoffersen, M., Dalila, N., Nielsen, L. B., Tybjærg-Hansen, Anne & Christoffersen, Christina, 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 9, p. 3046-3057Research output: Contribution to journal › Journal article › Research › peer-review
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A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation
Hajny, Stefan & Christoffersen, Christina, 27 Jul 2017, In: International Journal of Molecular Sciences. 18, 8, 19 p., 1636.Research output: Contribution to journal › Review › Research › peer-review
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(18)F-FDG PET imaging of murine atherosclerosis: association with gene expression of key molecular markers
Hag, Anne Mette Fisker, Pedersen, S. F., Christoffersen, Christina, Binderup, Tina, Wessel, Mette Munk, Jørgensen, Jesper Tranekjær, Skovgaard, D., Ripa, Rasmus Sejersten & Kjær, Andreas, 2012, In: P L o S One. 7, 11, p. e50908Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury
Guo, Z., Valenzuela Ripoll, C., Picataggi, A., Rawnsley, D. R., Ozcan, M., Chirinos, J. A., Chendamarai, E., Girardi, A., Riehl, T., Evie, H., Diab, A., Kovacs, A., Hyrc, K., Ma, X., Asnani, A., Shewale, S. V., Scherrer-Crosbie, M., Cowart, L. A., Parks, J. S., Zhao, L. & 14 others, , 2023, In: JACC: Basic to Translational Science. 8, 3, p. 340-355Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice
Gordts, P. L. S. M., Bartelt, A., Nilsson, S. K., Annaert, W., Christoffersen, Christina, Nielsen, L. B., Heeren, J. & Roebroek, A. J. M., 2012, In: P L o S One. 7, 6, p. e38330Research output: Contribution to journal › Journal article › Research › peer-review
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Increased cardiac BNP expression associated with myocardial ischemia
Goetze, Jens P. , Christoffersen, Christina, Perko, M., Arendrup, H., Rehfeld, Jens Frederik, Kastrup, J. & Nielsen, L. B., Jun 2003, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 17, 9, p. 1105-7 3 p.Research output: Contribution to journal › Journal article › Research
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Neonatal HDL Counteracts Placental Vascular Inflammation via S1P-S1PR1 Axis
Gaudio, I. D., Hendrix, S., Christoffersen, Christina & Wadsack, C., 25 Jan 2020, In: International Journal of Molecular Sciences. 21, 3, 789.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice
Galsgaard, Katrine Douglas, Elmelund, E., Johansen, C. D., Billeschou, Anna, Kizilkaya, Hüsün Sheyma, Ceutz, F., Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Winther-Sørensen, Marie, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Rosenkilde, Mette, Ørskov, Cathrine, Christoffersen, Christina, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Molecular Metabolism. 66, 14 p., 101639.Research output: Contribution to journal › Journal article › Research › peer-review
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High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression
Feuerborn, R., Becker, S., Potì, F., Nagel, P., Brodde, M., Schmidt, H., Christoffersen, Christina, Ceglarek, U., Burkhardt, R. & Nofer, J., Feb 2017, In: Atherosclerosis. 257, p. 29-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional brown adipose tissue and sympathetic activity after cold exposure in humans with type 1 narcolepsy
Enevoldsen, L. H., Tindborg, M., Hovmand, N. L., Christoffersen, Christina, Ellingsgaard, H., Suetta, Charlotte, Stallknecht, Bente Merete, Jennum, Poul, Kjær, Andreas & Gammeltoft, S., 2018, In: Sleep. 41, 8, p. 1-9 zsy092.Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL
Elsøe, S., Ahnström, J., Christoffersen, Christina, Hoofnagle, A. N., Plomgaard, Peter Stendahl, Heinecke, J. W., Binder, C. J., Björkbacka, H., Dahlbäck, B. & Nielsen, L. B., 2012, In: Atherosclerosis. 221, 1, p. 91-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein M promotes mobilization of cellular cholesterol in vivo
Elsøe, S., Christoffersen, Christina, Luchoomun, J., Turner, S. & Nielsen, L. B., Jul 2013, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1831, 7, p. 1287-92 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of Glomerular and Plasma Apolipoprotein M as Novel Biomarkers in Glomerular Disease
Drexler, Y., Molina, J., Elfassy, T., Ma, R., Christoffersen, Christina, Kurano, M., Yatomi, Y., Mariani, L. H., Contreras, G., Merscher, S. & Fornoni, A., 2023, In: Kidney International Reports. 8, 4, p. 884-897Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver
Ding, B., Liu, C. H., Sun, Y., Chen, Y., Swendeman, S. L., Jung, B., Chavez, D., Cao, Z., Christoffersen, Christina, Nielsen, L. B., Schwab, S. R., Rafii, S. & Hla, T., 22 Dec 2016, In: JCI insight. 1, 21, 16 p., e87058.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair
Ding, B. S., Yang, D., Swendeman, S. L., Christoffersen, Christina, Nielsen, L. B., Friedman, S. L., Powell, C. A., Hla, T. & Cao, Z., 2020, In: Developmental Cell. 53, 6, p. 677-690Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating cord blood HDL-S1P complex preserves the integrity of the feto-placental vasculature
Del Gaudio, I., Sreckovic, I., Zardoya-Laguardia, P., Bernhart, E., Christoffersen, Christina, Frank, S., Marsche, G., Illanes, S. E. & Wadsack, C., 2020, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1865, 4, 11 p., 158632.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Apolipoprotein M: Structure and Function
Dahlback, B., Ahnstrom, J., Christoffersen, Christina & Nielsen, L. B., 2008, In: Future Lipidology. 3, p. 495-503Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ApoB and apoM - New aspects of lipoprotein biology in uremia-induced atherosclerosis
Christoffersen, Christina, Bartels, Emil Daniel, Pedersen, A. A., Nielsen, L. B. & Pedersen, T. X., Dec 2017, In: European Journal of Pharmacology. 816, p. 154-160 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The signal peptide anchors apolipoprotein m in plasma lipoproteins and prevents rapid clearance of apolipoprotein m from plasma
Christoffersen, Christina, Ahnstrom, J., Axler, O., Christensen, E. I., Dahlback, B. & Nielsen, L. B., 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 6, p. E62-E63Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes and the endocrine heart
Christoffersen, Christina, Hunter, I., Jensen, Asger Lundorff & Goetze, Jens P. , Oct 2007, In: European Heart Journal. 28, 20, p. 2427-9 3 p.Research output: Contribution to journal › Editorial › Research
- Published
Apolipoprotein M - a new biomarker in sepsis
Christoffersen, Christina & Nielsen, L. B., 2012, In: Critical Care (Online Edition). 16, 3, p. 126Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Apolipoprotein M-A Marker or an Active Player in Type II Diabetes?
Christoffersen, Christina, 2021, In: Frontiers in Endocrinology. 12, 10 p., 665393.Research output: Contribution to journal › Review › Research › peer-review
- Published
Isolation and characterization of human apolipoprotein M-containing lipoproteins
Christoffersen, Christina, Nielsen, L. B., Axler, O., Andersson, A., Johnsen, A. H. & Dahlbäck, B., Aug 2006, In: Journal of Lipid Research. 47, 8, p. 1833-43 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The plasma concentration of HDL-associated apolipoprotein M is influenced by LDL-receptor-mediated clearance of apoB-containing particles
Christoffersen, Christina, Benn, Marianne, Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dahlback, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The signal peptide anchors apolipoprotein M in plasma lipoproteins and prevents rapid clearance of apolipoprotein M from plasma
Christoffersen, Christina, Ahnström, J., Axler, O., Christensen, E. I., Dahlbäck, B. & Nielsen, L. B., 2008, In: Journal of Biological Chemistry. 283, 27, p. 18765-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Apolipoprotein M: progress in understanding its regulation and metabolic functions
Christoffersen, Christina, Dahlbäck, B. & Nielsen, L. B., 2006, In: Scandinavian Journal of Clinical & Laboratory Investigation. 66, 7, p. 631-7 7 p.Research output: Contribution to journal › Journal article › Research
- Published
Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice
Christoffersen, Christina, Jauhiainen, M., Moser, M., Porse, Bo Torben, Ehnholm, C., Boesl, M., Dahlbäck, B. & Nielsen, L. B., 25 Jan 2008, In: The Journal of Biological Chemistry. 283, 4, p. 1839-47 9 p.Research output: Contribution to journal › Journal article › Research
- Published
Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M
Christoffersen, Christina, Obinata, H., Kumaraswamy, S. B., Galvani, S., Ahnström, J., Sevvana, M., Egerer-Sieber, C., Muller, Y. A., Hla, T., Nielsen, L. B. & Dahlbäck, B., 2011, In: Proceedings of the National Academy of Sciences USA (PNAS). 108, 23, p. 9613-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Opposing effects of apolipoprotein m on catabolism of apolipoprotein B-containing lipoproteins and atherosclerosis
Christoffersen, Christina, Pedersen, T. X., Gordts, P. L. S. M., Roebroek, A. J. M., Dahlbäck, B. & Nielsen, L. B., 2010, In: Circulation Research. 106, 10, p. 1624-34 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Apolipoprotein M: bridging HDL and endothelial function
Christoffersen, Christina & Nielsen, L. B., Aug 2013, In: Current Opinion in Lipidology. 24, 4, p. 295-300 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity
Christoffersen, Christina, Federspiel, C. K., Borup, A., Christensen, P. M., Madsen, A. N., Heine, M., Nielsen, C. H., Kjaer, A., Holst, Birgitte, Heeren, J. & Nielsen, L. B., 2 Jan 2018, In: Cell Reports. 22, 1, p. 175-188Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heart specific up-regulation of genes for B-type and C-type natriuretic peptide receptors in diabetic mice
Christoffersen, Christina, Bartels, Emil Daniel & Nielsen, L. B., Feb 2006, In: European Journal of Clinical Investigation. 36, 2, p. 69-75 7 p.Research output: Contribution to journal › Journal article › Research
- Published
Chamber-dependent expression of brain natriuretic peptide and its mRNA in normal and diabetic pig heart
Christoffersen, Christina, Goetze, Jens P. , Bartels, Emil Daniel, Larsen, T. M., Ribel, U., Rehfeld, Jens Frederik, Rolin, B. & Nielsen, L. B., Jul 2002, In: Hypertension. 40, 1, p. 54-60 7 p.Research output: Contribution to journal › Journal article › Research
- Published
Cardiac lipid accumulation associated with diastolic dysfunction in obese mice
Christoffersen, Christina, Bollano, E., Lindegaard, M. L. S., Bartels, Emil Daniel, Goetze, Jens P. , Andersen, C. B. & Nielsen, L. B., Aug 2003, In: Molecular Endocrinology. 144, 8, p. 3483-90 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heparininduceret trombocytopeni
Christoffersen, Christina, Lethagen, S. & Goetze, Jens P. , 16 Feb 2009, In: Ugeskrift for Laeger. 171, 8, p. 612-5 4 p.Research output: Contribution to journal › Journal article › Research
- Published
Apolipoprotein M: Impact on lipoprotein metabolism and vascular function
Christoffersen, Christina, 2014, Frederiksberg: Det Sundhedsvidenskabelige Fakultet, Københavns Universitet. 118 p.Research output: Book/Report › Doctoral thesis › Research
- Published
Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes
Christensen, P. M., Bosteen, M. H., Hajny, Stefan, Nielsen, L. B. & Christoffersen, Christina, 8 Nov 2017, In: Scientific Reports. 7, 10 p., 14983.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired endothelial barrier function in apolipoprotein M-deficient mice is dependent on sphingosine-1-phosphate receptor 1
Christensen, P. M., Liu, C. H., Swendeman, S. L., Obinata, H., Qvortrup, Klaus, Nielsen, L. B., Hla, T., Di Lorenzo, A. & Christoffersen, Christina, Jun 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 6, p. 2351-2359 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
The role of aetiology in cardiac manifestations of chronic kidney disease: the CPH-CKD ECHO study
Christensen, J., Landler, N. E., Olsen, F. J., Sørensen, I. M. H., Bjergfelt, S. S., Ballegaard, E. L. F., Feldt-Rasmussen, Bo, Hansen, Ditte, Kamper, A. L., Christoffersen, Christina, Bro, S. & Biering-Sørensen, Tor, 2024, (E-pub ahead of print) In: International Journal of Cardiovascular Imaging.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Left ventricular structure and function in patients with chronic kidney disease assessed by 3D echocardiography: the CPH-CKD ECHO study
Christensen, J., Landler, N. E., Olsen, F. J., Feldt-Rasmussen, Bo, Hansen, Ditte, Kamper, A. L., Christoffersen, Christina, Ballegaard, E. L. F., Sørensen, I. M. H., Bjergfelt, S. S., Seidelin, E., Bro, S. & Biering-Sørensen, Tor, 2022, In: International Journal of Cardiovascular Imaging. 38, 6, p. 1233–1244 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure
Chirinos, J. A., Zhao, L., Jia, Y., Frej, C., Adamo, L., Mann, D., Shewale, S. V., Millar, J. S., Rader, D. J., French, B., Brandimarto, J., Margulies, K. B., Parks, J. S., Wang, Z., Sieffert, D. A., Fang, J., Sweitzer, N., Christoffersen, C., Dahlbäck, B., Car, B. D. & 3 others, , 2020, In: Circulation. 141, 18, p. 1463–1476Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diurnal regulation of sphingolipids in blood
Brunkhorst, R., Pfeilschifter, W., Rajkovic, N., Pfeffer, M., Fischer, C., Korf, H. W., Christoffersen, Christina, Trautmann, S., Thomas, D., Pfeilschifter, J. & Koch, A., 2019, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1864, 3, p. 304-311Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein unfolding allows use of commercial antibodies in an apolipoprotein M sandwich ELISA
Bosteen, M. H., Dahlbäck, B., Nielsen, L. B. & Christoffersen, Christina, 1 Mar 2015, In: Journal of Lipid Research. 56, 3, p. 754-759 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of apolipoprotein M in uremic atherosclerosis
Bosteen, M. H., Madsen Svarrer, E. M., Bisgaard, Line, Martinussen, Torben, Madsen, M., Nielsen, L. B., Christoffersen, Christina & Pedersen, T. X., Oct 2017, In: Atherosclerosis. 265, p. 93-101 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of apolipoprotein M and sphingosine-1-phosphate with brown adipose tissue after cold exposure in humans
Borup, A., Donkin, I., Boon, M. R., Frydland, M., Martinez-Tellez, B., Loft, A., Keller, S. H., Kjær, Andreas, Kjærgaard, Jesper, Hassager, Christian, Barrès, Romain, Rensen, P. C. N. & Christoffersen, Christina, 2022, In: Scientific Reports. 12, 1, 11 p., 18753.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Apolipoprotein M in lipid metabolism and cardiometabolic diseases
Borup, A., Christensen, P. M., Nielsen, L. B. & Christoffersen, Christina, Feb 2015, In: Current Opinion in Lipidology. 26, 1, p. 48-55 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Induction of atherosclerosis in mice and hamsters without germline genetic engineering
Bjørklund, M. M., Hollensen, A. K., Hagensen, M. K., Dagnæs-Hansen, F., Christoffersen, Christina, Mikkelsen, J. G. & Bentzon, J. F., 23 May 2014, In: Circulation Research. 114, 11, p. 1684-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carotid plaque thickness is increased in chronic kidney disease and associated with carotid and coronary calcification
Bjergfelt, S. S., Sørensen, I. M. H., Hjortkjær, H., Landler, N., Ballegaard, E. L. F., Biering-Sørensen, Tor, Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Sillesen, Henrik, Christoffersen, Christina & Bro, S., 2021, In: PLoS ONE. 16, 16 p., e0260417.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KIDNEY DERIVED APOM AND ITS ROLE IN ACUTE KIDNEY INJURY
Bisgaard, Line, Christensen, P. M., Fuchtbauer, E., Nielsen, L. B. & Christoffersen, Christina, 2021, In: Nephrology Dialysis Transplantation. 36, Suppl. 1, p. 240-240 MO339.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Apolipoprotein M/sphingosine-1-phosphate: novel effects on lipids, inflammation and kidney biology
Bisgaard, L. S. & Christoffersen, Christina, 2019, In: Current Opinion in Lipidology. 30, 3, p. 212-217Research output: Contribution to journal › Review › Research › peer-review
- Published
Kidney derived apolipoprotein M and its role in acute kidney injury
Bisgaard, Line, Christensen, P. M., Oh, J., Torta, F., Füchtbauer, E. M., Nielsen, L. B. & Christoffersen, Christina, 2024, In: Frontiers in Pharmacology. 15, 1328259.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The apoM/S1P Complex - A Mediator in Kidney Biology and Disease?
Bisgaard, Line & Christoffersen, Christina, 2021, In: Frontiers in Medicine. 8, 11 p., 754490.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effect of atrial natriuretic peptide on lipolysis in the mouse heart
Bartels, Emil Daniel, Bisgaard, Line, Christoffersen, Christina & Nielsen, L. B., 2014, In: Cardiovascular Endocrinology. 3, 3, p. 92-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered Metabolism of LDL in the Arterial Wall Precedes Atherosclerosis Regression
Bartels, Emil Daniel, Christoffersen, Christina, Lindholm, M. W. & Nielsen, L. B., 2015, In: Circulation Research. 117, p. 933-942 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The apolipoprotein m-sphingosine-1-phosphate axis: biological relevance in lipoprotein metabolism, lipid disorders and atherosclerosis
Arkensteijn, B. W. C., Berbée, J. F. P., Rensen, P. C. N., Nielsen, L. B. & Christoffersen, Christina, 25 Feb 2013, In: International Journal of Molecular Sciences (Online). 14, 3, p. 4419-31 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant
Al-Mashhadi, R. H., Sørensen, C. B., Kragh, P. M., Christoffersen, C., Mortensen, M. B., Tolbod, L. P., Thim, T., Du, Y., Li, J., Liu, Y., Moldt, B., Schmidt, M., Vajta, G., Larsen, T., Purup, S., Bolund, L., Nielsen, L. B., Callesen, H., Falk, E., Mikkelsen, J. G. & 1 others, , 2013, In: Science Translational Medicine. 5, 166, 11 p., 166ra1.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes with poor glycaemic control does not promote atherosclerosis in genetically modified hypercholesterolaemic minipigs
Al-Mashhadi, R. H., Bjørklund, M. M., Mortensen, M. B., Christoffersen, Christina, Larsen, T., Falk, E. & Bentzon, J. F., 2015, In: Diabetologia. 58, 8, p. 1926-36 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 18392597
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A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation
Research output: Contribution to journal › Review › Research › peer-review
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252
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Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
240
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The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity
Research output: Contribution to journal › Journal article › Research › peer-review
Published