Osteopontin deficiency dampens the pro-atherogenic effect of uraemia
Research output: Contribution to journal › Journal article › Research › peer-review
Uraemia is a strong risk factor for cardiovascular disease. Osteopontin (OPN) is highly expressed in aortas of uraemic apolipoprotein E knockout (E KO) mice. OPN affects key atherogenic processes, i.e. inflammation and phenotypic modulation of smooth muscle cells (SMCs). We explored the role of OPN on vascular pathology in uraemic mice.
| Original language | English |
|---|---|
| Journal | Cardiovascular Research |
| Volume | 98 |
| Issue number | 3 |
| Pages (from-to) | 352-9 |
| Number of pages | 8 |
| ISSN | 0008-6363 |
| DOIs | |
| Publication status | Published - 1 Jun 2013 |
ID: 45810489