Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 2005
- Published
For debate: Are antidiabetic actions of DPP-IV inhibitors mediated by glucagon-like peptide- 1?
Holst, Jens Juul & Deacon, Carolyn F., 2005, In: Diabetologia. 48, p. 612-615Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 receptor argonists for the treatment of diabetes
Holst, Jens Juul, 2005, In: International Diabetes Monitor. 17, p. 11-18Research output: Contribution to journal › Journal article › Research
- Published
GLP-2 dose-dependently activates intestinal cell survival and proliferation in neonatal piglets
Burrin, D. G., Stoll, B., Guan, X., Cui, L., Chang, X. & Holst, Jens Juul, 2005, In: Endokrinologiya. 146, p. 22-32Research output: Contribution to journal › Journal article › Research
- Published
GLP-2 stimulates colonic growth via KGF, released by subepithelial myofibroblasts with GLP-2 receptors.
Ørskov, Cathrine, Hartmann, B., Poulsen, Steen Seier, Thulesen, J., Hare, K. J. & Holst, Jens Juul, 2005, In: Regulatory Peptides. 124, 1-3, p. 105-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1: physiology and therapeutic potential
Holst, Jens Juul, 2005, In: Endocrinology and Diabetes. 12, p. 56-62Research output: Contribution to journal › Journal article › Research
- Published
Glucagon-like peptide-1 mediates the therapeutic actions of Dpp-IV inhibitors
Holst, Jens Juul & Deacon, Carolyn F., 2005, In: Diabetologia. 48, p. 612-615Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like-peptide-2 (GLP-2) response to enteral intake in children during anticancer treatment
Andreassen, B. U., Pærregaard, A., Schmiegelow, K., Rechnitzer, C., Hartmann, B., Holst, Jens Juul & Michaelsen, K. F., 2005, In: Journal of Pediatric Gastroenterology and Nutrition. 40, p. 48-53Research output: Contribution to journal › Journal article › Research
- Published
Glucagon-related peptide 1 (GLP-1): hormone and neurotransmitter.
Larsen, P. J. & Holst, Jens Juul, 2005, In: Regulatory Peptides. 128, 2, p. 97-107 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of cereal fibre on glucose regulating factors
Weickert, M. O., Moehlig, M., Koebnick, C., Holst, Jens Juul, Namsolleck, P., Ristow, M., Osterhoff, M., Rochlitz, H., Rudovich, N., Spranger, J. & Pleiffer, A. F. H., 2005, In: Diabetologia. 48, p. 2343-2353Research output: Contribution to journal › Journal article › Research
- Published
Inhibition of human pancreatic and biliary output but not intestinal motility by physiological intraileal lipid loads.
Keller, J., Holst, Jens Juul & Layer, P., 2005, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 290, 4, p. G704-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulinotropic effect of gastric inhibitory polypeptide (GIP) in women with a history of gestational diabetes
Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2005, In: Diabetologia. 48, p. 1872-1881Research output: Contribution to journal › Journal article › Research
- Published
Lower-body fat mass as an independent marker of insulin sensitivity - the role of adiponectin?
Buemann, B., Black, E., Sørensen, Thorkild I.A., Holst, C., Toubro, S., Pedersen, O., Holst, Jens Juul, Rasmussen, C. & Astrup, A., 2005, In: International Journal of Obesity. 29, p. 624-631Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neutral Endopeptidase 24.11 and dipeptidyl peptidase IV are both physiological mediators of the degradation of glucagon-like peptide-1 in the anaesthetized pig
Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2005, In: Diabetologia. 48, p. 1882-1890Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal secretion and action of the gut incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in young men with low birth weight
Schou, J. H., Pilgaard, K., Vilsbøll, Tina, Jensen, C. B., Deacon, Carolyn F., Holst, Jens Juul, Vølund, A., Madsbad, Sten & Vaag, Allan, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 8, p. 4912-19 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Severe hypoglycemia post-gastric bypass requiring partial pancreatectomy: Evidence for inappropriate insulin secretion and pancreatic islet cell hyperplasia
Patti, M. E., Mun, E. C., Holst, Jens Juul, Hanto, D. W., Goldsmith, J., Arky, R., Nose, V., Bonner-Weir, S. & Goldfine, A. B., 2005, In: Diabetologia. 48, p. 2236-2240Research output: Contribution to journal › Journal article › Research
- Published
Teduglutide (ALX-0600), a dipeptidyl-peptidase-IV resistant glucagon-like-2 analog improves intestinal function in short bowel syndrome patients
Jeppesen, P. B., Sanguinetti, E. L., Buckman, A., Howard, L., Scolapio, J. S., Ziegler, T. R., Gregory, M., Tappendent, K. A., Holst, Jens Juul & Mortensen, P. B., 2005, In: Gut. 54, p. 1224-1231Research output: Contribution to journal › Journal article › Research
- Published
The incretin enhancer vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed -cell function in patients with type 2 diabetes
Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Dunning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, p. 4888-4894Research output: Contribution to journal › Journal article › Research
- Published
The use of glycaemic index tables to predict glycaemic index of breakfast meals
Flint, A., Møller, B. K., Raben, Anne, Tetens, Inge , Holst, Jens Juul & Astrup, A., 2005, In: British Journal of Nutrition. 94, 1, p. 135-136 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Tissue levels and postprandial secretion of the intestinal growth factor, GLP-2 in inflammatory bowels disease: comparison with PYY
Schmidt, P. T., Ljung, T., Hartmann, B., Hare, K. J., Holst, Jens Juul & Hëllstrøm, P. M., 2005, In: European Journal of Gastroenterology and Hepathology. 17, p. 207-212Research output: Contribution to journal › Journal article › Research
- Published
Vildagliptin, a dipeptidyl peptidase-IV inhibitor improves model-assessed beta-cell function in patients with type 2 diabetes
Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Duning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 4888-4894Research output: Contribution to journal › Journal article › Research
- Published
Young, low-birth-weight men are not more susceptible to the diabetogenic effects of a prolonged free fatty acid exposure than matched controls.
Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, Flemming, Madsbad, Sten & Vaag, Allan, 2005, In: Metabolism - Clinical and Experimental. 54, 10, p. 1398-406 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells
Haugaard, Steen Bendix, Andersen, Ove, Dela, Flemming, Holst, Jens Juul, Storgaard, H., Fenger, M., Iversen, J. & Madsbad, Sten, Jan 2005, In: European Journal of Endocrinology. Supplement. 152, 1, p. 103-12 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 dose-dependently activates intestinal cell survival and proliferation in neonatal piglets
Burrin, D. G., Stoll, B., Guan, X., Cui, L., Chang, X. & Holst, Jens Juul, Jan 2005, In: Endocrinology. 146, 1, p. 22-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 (GLP-2) response to enteral intake in children during anti-cancer treatment
Andreassen, B. U., Paerregaard, A., Schmiegelow, Kjeld, Rechnitzer, C., Heilman, C., Hartmann, Bolette, Holst, Jens Juul & Michaelsen, Kim F., Jan 2005, In: Journal of Pediatric Gastroenterology and Nutrition. 40, 1, p. 48-53 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the physiology of GIP and GLP-1
Holst, Jens Juul, 19 Jan 2005, In: Hormone and Metabolic Research. Supplement. 36, 11-12, p. 747-54 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue levels and post-prandial secretion of the intestinal growth factor, glucagon-like peptide-2, in controls and inflammatory bowel disease: comparison with peptide YY
Schmidt, P. T., Ljung, T., Hartmann, Bolette, Hare, K. J., Holst, Jens Juul & Hellström, P. M., Feb 2005, In: European journal of gastroenterology & hepatology. 17, 2, p. 207-12 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhanced glucagon-like peptide-1 (GLP-1) response to oral glucose in glucose-intolerant HIV-infected patients on antiretroviral therapy
Andersen, Ove, Haugaard, Steen Bendix, Holst, Jens Juul, Deacon, Carolyn F., Iversen, J., Andersen, U. B., Nielsen, J. O. & Madsbad, Sten, Mar 2005, In: HIV Medicine. 6, 2, p. 91-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutrient-stimulated GLP-2 release and crypt cell proliferation in experimental short bowel syndrome
Martin, G. R., Wallace, L. E., Hartmann, Bolette, Holst, Jens Juul, Demchyshyn, L., Toney, K. & Sigalet, D. L., Mar 2005, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 288, 3, p. G431-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors
Holst, Jens Juul & Deacon, Carolyn F., Apr 2005, In: Diabetologia. 48, 4, p. 612-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
alpha-Glucosidase inhibition (acarbose) fails to enhance secretion of glucagon-like peptide 1 (7-36 amide) and to delay gastric emptying in Type 2 diabetic patients
Hücking, K., Kostic, Z., Pox, C., Ritzel, R., Holst, Jens Juul, Schmiegel, W. & Nauck, M. A., Apr 2005, In: Diabetic Medicine. 22, 4, p. 470-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erythromycin antagonizes the deceleration of gastric emptying by glucagon-like peptide 1 and unmasks its insulinotropic effect in healthy subjects
Meier, J. J., Kemmeries, G., Holst, Jens Juul & Nauck, M. A., Jul 2005, In: Diabetes. 54, 7, p. 2212-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed beta-cell function in patients with type 2 diabetes
Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Dunning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., Aug 2005, In: The Journal of clinical endocrinology and metabolism. 90, 8, p. 4888-94 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A role for pancreatic polypeptide in the regulation of gastric emptying and short-term metabolic control
Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Holst, Jens Juul, Hilsted, Linda & Hellström, P. M., Sep 2005, In: The Journal of clinical endocrinology and metabolism. 90, 9, p. 5241-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig
Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., Sep 2005, In: Diabetologia. 48, 9, p. 1882-90 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of incretin hormones and the insulinotropic effect of gastric inhibitory polypeptide in women with a history of gestational diabetes
Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Sep 2005, In: Diabetologia. 48, 9, p. 1872-81 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes
Fehse, F., Trautmann, M., Holst, Jens Juul, Halseth, A. E., Nanayakkara, N., Nielsen, L. L., Fineman, M. S., Kim, D. D. & Nauck, M. A., Nov 2005, In: The Journal of clinical endocrinology and metabolism. 90, 11, p. 5991-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of cereal fibre on glucose-regulating factors
Weickert, M. O., Mohlig, M., Koebnick, C., Holst, Jens Juul, Namsolleck, P., Ristow, M., Osterhoff, M., Rochlitz, H., Rudovich, N., Spranger, J. & Pfeiffer, A. F. H., Nov 2005, In: Diabetologia. 48, 11, p. 2343-53 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia
Patti, M. E., McMahon, G., Mun, E. C., Bitton, A., Holst, Jens Juul, Goldsmith, J., Hanto, D. W., Callery, M., Arky, R., Nose, V., Bonner-Weir, S. & Goldfine, A. B., Nov 2005, In: Diabetologia. 48, 11, p. 2236-40 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Diet- and colonization-dependent intestinal dysfunction predisposes to necrotizing enterocolitis in preterm pigs
Sangild, Per Torp, Siggers, R. H., Schmidt, M., Elnif, J., Bjørnvad, Charlotte Reinhard, Thymann, Thomas, Grøndahl, M. L., Hansen, Axel Kornerup, Jensen, S. K., Boye, M., Moelbak, L., Buddington, R. K., Weström, B. R., Holst, Jens Juul & Burrin, D. G., 2006, In: Gastroenterology. 130, 6, p. 1776-1792 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of a high-protein breakfast on the postprandial ghrelin response
Blom, W. A. M., Lluch, A., Stafleu, A., Vinoy, S., Holst, Jens Juul, Schaafsma, G. & Hendriks, H. F. J., 2006, In: American Journal of Clinical Nutrition. 83, 2, p. 211-220 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.
Herman, G. A., Bergman, A., Stevens, C., Kotey, P., Yi, B., Zhao, P., Dietrich, B., Golor, G., Schrodter, A., Keymeulen, B., Lasseter, K. C., Kipnes, M. S., Snyder, K., Hilliard, D., Tanen, M., Cilissen, C., De Smet, M., de Lepeleire, I., Van Dyck, K., Wang, A. Q. & 7 others, , 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4612-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of PYY1-36 and PYY3-36 on appetite, energy intake, energy expenditure, glucose and fat metabolism in obese and lean subjects.
Sloth, B., Holst, Jens Juul, Flint, A., Gregersen, N. T. & Astrup, A., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 4, p. E1062-E1068 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of gastric emptying on the postprandial ghrelin response
Blom, W. A. M., Lluch, A., Vinoy, S., Stafleu, A., Berg, R. V. D., Holst, Jens Juul, Kok, F. J. & Hendriks, H. F. J., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 290, 2, p. E389-E395Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs
Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Diabetologia. 49, 4, p. 706-712 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs
Stoll, B., Price, P. T., Reeds, P. J., Chang, X., Henry, J. F., Goudoever, J. B. V., Holst, Jens Juul & Burrin, D. G., 2006, In: Journal of Parenteral and Enteral Nutrition. 30, 1, p. 32-39 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP-(3-42) does not antagonize insulinotropic effects of GIP at physiological concentrations.
Deacon, Carolyn F., Plamboeck, A., Rosenkilde, Mette, de Heer, J. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 3, p. E468-75Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow
Guan, X. F., Karpen, H. E., Stephens, J., Bukowski, J. T., Niu, S. Y., Zhang, G. C., Stoll, B., Finegold, M. J., Holst, Jens Juul, Hadsell, D. L., Nichols, B. L. & Burrin, D. G., 2006, In: Today in Medicine. Gastroenterology. 130, 1, p. 150-164 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ghrelin stimulates gastric emptying and hunger in normal-weight humans
Levin, F., Edholm, T., Schmidt, P. T., Gryback, P., Jacobsson, H., Degerblad, M., Hoybye, C., Holst, Jens Juul, Rehfeld, J. F., Hellstrom, P. M. & Naslund, E., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 9, p. 3296-3302 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans
Meier, J. J., Gethmann, A., Gotze, O., Gallwitz, B., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2006, In: Diabetologia. 49, 3, p. 452-458 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans
Meier, J. J., Nauck, M. A., Pott, A., Heinze, K., Goetze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, 2006, In: Today in Medicine. Gastroenterology. 130, 1, p. 44-54 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1: From extract to agent. The Claude Bernard Lecture, 2005
Holst, Jens Juul, 2006, In: Diabetologia. 49, 2, p. 253-260 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin.
Holst, Jens Juul & Kastin, A., 2006, Handbook of biologically active peptides. Amsterdam: Elsevier, p. 1057-1064 7 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagons, lactate and TNF-alfa in patients with HIV-lipodystrophy
Haugaard, S. B., Andersen, Ove, Pedersen, S., Dela, Flemming, Holst, Jens Juul, Deacon, Carolyn F., Iversen, J. & Madsbad, Sten, 2006, In: HIV Medicine. 7, p. 163-172 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycemic and insulinemic responses as determinants of appetite in humans
Flint, A., Møller, B. K., Raben, Anne, Sloth, B., Pedersen, D., Tetens, Inge , Holst, Jens Juul & Astrup, A., 2006, In: American Journal of Clinical Nutrition. 84, 6, p. 1365-1373 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice.
Sørensen, H., Brand, C. L., Neschen, S., Holst, Jens Juul, Fosgerau, K., Nishimura, E. & Shulman, G. I., 2006, In: Diabetes. 55, 10, p. 2843-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of incretin hormones on beta-cell function in subjects with normal or impaired glucose tolerance
Muscelli, E., Mari, A., Natali, A., Astiarraga, B. D., Camastra, S., Frascerra, S., Holst, Jens Juul & Ferrannini, E., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 6, p. E1144-E1150Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased postprandial responses of GLP-1 and GIP in patients with chronic pancreatitis and steatorrhea following pancreatic enzyme substitution.
Knop, F. K., Vilsbøll, Tina, Larsen, S., Højberg, P. V., Vølund, A., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 1, p. E324-30Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin mimetics in the treatment of type 2 diabetes mellitus
Holst, Jens Juul & Hughes, T., 2006, European Endocrine Disease 2006. London: Touch Briefings, p. 17-19 2 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Influence of gastric inhibitory polypeptide on pentagastrin-stimulated gastric acid secretion in patients with type 2 diabetes and healthy controls.
Meier, J. J., Nauck, M. A., Kask, B., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2006, In: World Journal of Gastroenterology. 12, 12, p. 1874-80 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibitory effect of GLP-1 on gastric motility persists after vagal deafferentation in pigs.
Nagell, C. F., Wettergren, A., Ørskov, Cathrine & Holst, Jens Juul, 2006, In: Scandinavian Journal of Gastroenterology. 41, 6, p. 667-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolism of glucagon-like peptide-2 in pigs: role of dipeptidyl peptidase IV.
Hansen, L., Hare, K. J., Hartmann, B., Deacon, Carolyn F., Ugleholdt, Randi Kjærsgaard, Plamboeck, A. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 138, 2-3, p. 126-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Possible role of adiponectin and insulin sensitivity in mediating the favorable effects of lower body fat mass on blood lipids
Buemann, B., Astrup, A., Pedersen, O., Black, E., Holst, C., Toubro, S., Echwald, S., Holst, Jens Juul, Rasmussen, C. & Sørensen, Thorkild I.A., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 5, p. 1698-1704 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor
Ugleholdt, Randi Kjærsgaard, Poulsen, M. H., Holst, Peter Johannes, Irminger, J., Orskov, C., Pedersen, Jens, Rosenkilde, Mette, Zhu, X., Steiner, D. F. & Holst, Jens Juul, 2006, In: Journal of Biological Chemistry. 281, 16, p. 11050-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of GLP-1 analogues and DDP-IV inhibitors in the treatment of type 2 diabetes
Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Avances en Diabetologia. 22, 2, p. 115-125 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stimulation of glucagon secretion and inhibition of gastric acid secretion by glucagon-like peptide-2 (GLP-2) in healthy human subjects
Meier, J., Nauck, M. A., Pott, A., Heinze, K., Götze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, 2006, In: Today in Medicine. Gastroenterology. 130, p. 44-54Research output: Contribution to journal › Journal article › Research
- Published
Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations
Pearson, E. R., Flechtner, I., Njolstad, P. R., Malecki, M. T., Flanagan, S. E., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J., Holst, Jens Juul, Clark, P. M., Ellard, S., Sovik, O., Polak, M. & Hattersley, A. T., 2006, In: New England Journal of Medicine. 355, 5, p. 467-477 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synergistic effect of supplemental enteral nutrients and exogenous glucagon-like peptide 2 on intestinal adaptation in a rat model of short bowel syndrome
Liu, X. W., Nelson, D. W., Holst, Jens Juul & Ney, D. M., 2006, In: American Journal of Clinical Nutrition. 84, 5, p. 1142-1150 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect o a high protein dairy breakfast on the postprandial ghrelin response
Blom, W. A. M., Lluch, A., Stafleu, A., Vinoy, S., Holst, Jens Juul, Schaafsma, G. & Hendriks, H. F. K., 2006, In: Am. J. Clin. Nutr.. 83, p. 211-220Research output: Contribution to journal › Journal article › Research
- Published
The effects of gastric emptying on the postprandial ghrelin response
Blom, W., Lluch, A., Vinoy, S., Stafleu, A., Van den Berg, R., Holst, Jens Juul, Kok, F. J. & Hendriks, H. F. K., 2006, In: Am. J. Physiol.. 290, p. E389-E395Research output: Contribution to journal › Journal article › Research
- Published
The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.
Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans.
Meier, J. J., Gethmann, A., Nauck, M. A., Götze, O., Schmitz, F., Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 290, 6, p. E1118-23Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes
Zander, M., Madsbad, S., Deacon, Carolyn F. & Holst, Jens Juul, 2006, In: Diabetologia. 49, 2, p. 369-374 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The rate of intestinal glucose absorption is correlated with plasma glucose-dependent insulinotropic polypeptide concentrations in healthy men
Wachters-Hagedoorn, R. E., Priebe, M. G., Heimweg, J. A. J., Heiner, A. M., Englyst, K. N., Holst, Jens Juul, Stellaard, F. & Vonk, R. J., 2006, In: Journal of Nutrition. 136, 6, p. 1511-1516 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The successful transfer of insulin treated patients with diabetes due to Kir6.2 (KCNJ11) mutations to oral sulfonylureas
Pearson, E. R., Flechtner, I., Njølståd, P. R., Malecki, M. T., Flanagan, S., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J. J., Holst, Jens Juul, Clark, P. M., Ellard, S. E., Sovik, O., Polak, M. & Hattersley, A. T., 2006, In: N. Engl. J. Med.. 355, p. 467-477Research output: Contribution to journal › Journal article › Research
- Published
Vagal afferents are essential for maximal resection-induced intestinal adaptive growth in orally fed rats
Nelson, D. W., Liu, X. W., Holst, Jens Juul, Raybould, H. E. & Ney, D. M., 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 5, p. R1256-R1264Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety
Weickert, M. O., Spranger, J., Holst, Jens Juul, Otto, B., Koebnick, C., Moehlig, M. & Pfeiffer, A. F. H., 2006, In: British Journal of Nutrition. 96, 5, p. 795-798 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow
Guan, X., Karpen, H. E., Stephens, J., Bukowski, J. T., Niu, S., Zhang, G., Stoll, B., Finegold, M. J., Holst, Jens Juul, Hadsell, D., Hadsell, D. L., Nichols, B. L. & Burrin, D. G., Jan 2006, In: Gastroenterology. 130, 1, p. 150-64 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans
Meier, J. J., Nauck, M. A., Pott, A., Heinze, K., Goetze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, Jan 2006, In: Gastroenterology. 130, 1, p. 44-54 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs
Stoll, B., Price, P. T., Reeds, P. J., Chang, X., Henry, J. F., van Goudoever, J. B., Holst, Jens Juul & Burrin, D. G., 3 Jan 2006, In: Journal of Parenteral and Enteral Nutrition. 30, 1, p. 32-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of a high-protein breakfast on the postprandial ghrelin response
Blom, W. A. M., Lluch, A., Stafleu, A., Vinoy, S., Holst, Jens Juul, Schaafsma, G. & Hendriks, H. F. J., Feb 2006, Effect of a high-protein breakfast on the postprandial ghrelin response. Vol. 83. p. 211-20 10 p. (Uden navn).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Glucagon-like peptide-1: from extract to agent. The Claude Bernard Lecture, 2005
Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 253-60 8 p.Research output: Contribution to journal › Journal article › Communication
- Published
The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes
Zander, M., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 369-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans
Meier, J. J., Gethmann, A., Götze, O., Gallwitz, B., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Mar 2006, In: Diabetologia. 49, 3, p. 452-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs
Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., Apr 2006, In: Diabetologia. 49, 4, p. 706-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The rate of intestinal glucose absorption is correlated with plasma glucose-dependent insulinotropic polypeptide concentrations in healthy men
Wachters-Hagedoorn, R. E., Priebe, M. G., Heimweg, J. A. J., Heiner, A. M., Englyst, K. N., Holst, Jens Juul, Stellaard, F. & Vonk, R. J., Jun 2006, In: Journal of Nutrition. 136, 6, p. 1511-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations
Pearson, E. R., Flechtner, I., Njølstad, P. R., Malecki, M. T., Flanagan, S. E., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J., Holst, Jens Juul, Clark, P. M., Ellard, S., Søvik, O., Polak, M., Hattersley, A. T. & Neonatal Diabetes International Collaborative Group, N. D. I. C. G., 3 Aug 2006, In: New England Journal of Medicine. 355, 5, p. 467-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ghrelin stimulates gastric emptying and hunger in normal-weight humans
Levin, F., Edholm, T., Schmidt, P. T., Grybäck, P., Jacobsson, H., Degerblad, M., Höybye, C., Holst, Jens Juul, Rehfeld, Jens Frederik, Hellström, P. M. & Näslund, E., Sep 2006, In: The Journal of clinical endocrinology and metabolism. 91, 9, p. 3296-302 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake
Ryskjaer, J., Deacon, Carolyn F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Vilsbøll, Tina, Ryskjaer, J., Deacon, C. F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, J. J. & Vilsbøll, T., 1 Sep 2006, In: European Journal of Endocrinology. 155, 3, p. 485-93 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synergistic effect of supplemental enteral nutrients and exogenous glucagon-like peptide 2 on intestinal adaptation in a rat model of short bowel syndrome
Liu, X., Nelson, D. W., Holst, Jens Juul & Ney, D. M., Nov 2006, In: Uden navn. 84, 5, p. 1142-50 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vagal afferents are essential for maximal resection-induced intestinal adaptive growth in orally fed rats
Nelson, D. W., Liu, X., Holst, Jens Juul, Raybould, H. E. & Ney, D. M., Nov 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 5, p. R1256-64Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety
Weickert, M. O., Spranger, J., Holst, Jens Juul, Otto, B., Koebnick, C., Möhlig, M. & Pfeiffer, A. F. H., Nov 2006, In: The British Journal of Nutrition. 96, 5, p. 795-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of incretin hormones on beta-cell function in subjects with normal or impaired glucose tolerance
Muscelli, E., Mari, A., Natali, A., Astiarraga, B. D., Camastra, S., Frascerra, S., Holst, Jens Juul & Ferrannini, E., Dec 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 6, p. E1144-50Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 inhibits ghrelin secretion in humans
Banasch, M., Bulut, K., Hagemann, D., Schrader, H., Holst, Jens Juul, Schmidt, W. E. & Meier, J. J., 10 Dec 2006, In: Regulatory Peptides. 137, 3, p. 173-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
Acute effects of ghrelin administration on glucose and lipid metabolism.
Vestergaard, E. T., Djurhuus, C. B., Gjedsted, J., Nielsen, S., Møller, N., Holst, Jens Juul, Jørgensen, J. O. L. & Schmitz, O., 2007, In: Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 438-444 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate
Holst, Jens Juul, Hartmann, B., Gottschalck, I. B., Jeppesen, P. B., Miholic, J. & Henriksen, D. B., 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-820 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cecal infusion of butyrate increases intestinal cell proliferation in piglets
Kien, C. L., Blauwiekel, R., Bunn, J. Y., Jetton, T. L., Frankel, W. L. & Holst, Jens Juul, 2007, In: Journal of Nutrition. 137, 4, p. 916-922 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes
Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, A. C., Jansen-Olesen, I., Chiarelli, F., Holst, J. J., Hougaard, P. P., Porksen, S., Holl, R., Beaufort, C. D., Gammeltoft, S., Rorsman, P., Mortensen, H. B., Hansen, L., Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, C., Jansen-Olesen, I. & 11 others, , 2007, In: European Journal of Endocrinology. 156, 6, p. 663-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disassociation of bone resorption and formation by GLP-2 - A 14-day study in healthy postmenopausal women
Henriksen, D. B., Alexandersen, P., Hartmann, B., Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2007, In: Bone. 40, 3, p. 723-729 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of dairy calcium or supplementary calcium on postprandial fat metabolism, appetite, and subsequent energy intake
Lorenzen, J. K., Nielsen, S., Holst, Jens Juul, Tetens, Inge , Rehfeld, Jens Frederik & Astrup, A., 2007, In: American Journal of Clinical Nutrition. 85, 3, p. 678-687 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acids concentration in obese males
Sloth, B., Davidsen, L., Holst, Jens Juul, Flint, A. & Astrup, A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 2, p. E604-E609Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteric neural pathways mediate the anti-inflammatory actions of glucagon-like peptide 2
Sigalet, D. L., Wallace, L. E., Holst, Jens Juul, Martin, G. R., Kaji, T., Tanaka, H. & Sharkey, K. A., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G211-G221Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding.
Korner, J., Bessler, M., Inabnet, W., Taveras, C. & Holst, Jens Juul, 2007, In: Surgery for Obesity and Related Diseases. 3, 6, p. 597-601 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats.
Simonsen, L., Pilgaard, S., Orskov, C., Rosenkilde, Mette, Hartmann, B., Holst, Jens Juul & Deacon, Carolyn F., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G288-95Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet
McClean, P. L., Irwin, N., Cassidy, R. S., Holst, Jens Juul, Gault, V. A. & Flatt, P. R., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 6, p. E1746-E1755Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion
Cani, P. D., Holst, Jens Juul, Drucker, D. J., Delzenne, N. M., Thorens, B., Burcelin, R. & Knauf, C., 2007, In: Molecular and Cellular Endocrinology. 276, 1-2, p. 18-23 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying of glucose solution and associated plasma concentrations of GLP-1, GIP, and PYY before and after fundoplication
Miholic, J., Hoffmann, M., Holst, Jens Juul, Lenglinger, J., Mittlbock, M., Bergmann, H. & Stacher, G., 2007, In: Surgical Endoscopy and Other Interventional Techniques. 21, 2, p. 309-314 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastrointestinal function and metabolic control after construction of an orthotopic ileal neobladder in bladder cancer.
Thorstenson, A., Jacobsson, H., Onelöv, E., Holst, Jens Juul, Hellström, P. M. & Kinn, A., 2007, In: Scandinavian Journal of Urology and Nephrology. 41, 1, p. 14-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 (GLP-1) suppresses ghrelin levels in humans via increased insulin secretion
Hagemann, D., Holst, Jens Juul, Gethmann, A., Banasch, M., Schmidt, W. E. & Meier, J. J., 2007, In: Regulatory Peptides. 143, 1-3, p. 64-68 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 has limited efficacy to increase nutrient absorption in fetal and preterm pigs
Sangild, Per Torp, Malo, C., Schmidt, M., Petersen, Y. M., Elnif, J., Holst, Jens Juul & Bunddington, R. K., 2007, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 293, 6, p. R2179-R2184 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 in umbilical cord blood from mature infants
Bodé, S., Hartmann, Bolette, Holst, Jens Juul & Greisen, Gorm, 2007, In: Neonatology. 91, 1, p. 49-53 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 in umbilical cord blood from mature infants
Bode, S., Hartmann, B., Holst, Jens Juul & Greisen, Gorm, 2007, In: Neonatology. 91, 1, p. 49-53 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic autoregulation: response of glucose production and gluconeogenesis to increased glycogenolysis
Stæhr, P. A., Hother-Nielsen, O., Beck-Nielsen, H., Roden, M., Stingl, H., Holst, Jens Juul, Jones, P. K., Chandramouli, V. & Landau, B. R., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 5, p. E1265-E1269Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms
Schafer, S. A., Tschritter, O., Machicao, F., Thamer, C., Stefan, N., Gallwitz, B., Holst, Jens Juul, Dekker, J. M., t'Hart, L. M., Nijpels, G., Haeften, T. W. V., Haring, H. U. & Fritsche, A., 2007, In: Diabetologia. 50, 12, p. 2443-2450 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes
Porksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Orskov, C., Holst, Jens Juul, Ploug, K. B., Hougaard, P. P., Hansen, L. & Mortensen, H. B., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 8, p. 2910-2916 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes
Azuma, K., Rádiková, Z., Mancino, J., Toledo, F. G. S., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D., Foley, J. E. & Kelley, D. E., 2007, In: Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 459-464 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic effects of amino acid mixtures and whey protein in healthy subjects: studies using glucose-equivalent drinks
Nilsson, M., Holst, Jens Juul & Bjorck, I. M. E., 2007, In: American Journal of Clinical Nutrition. 85, 4, p. 996-1004 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New horizons in diabetes therapy
Holst, Jens Juul & Deacon, Carolyn F., 2007, In: Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 7, 1, p. 49-55 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal secretion of the incretin hormones glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 during gestational diabetes mellitus
Cypryk, K., Vilsbøll, Tina, Nadel, I., Smyczynska, J., Holst, Jens Juul & Lewinski, A., 2007, In: Gynecological Endocrinology. 23, 1, p. 58-62 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal
Goldfine, A. B., Mun, E. C., Devine, E., Bernier, R., Baz-Hecht, M., Jones, D. B., Schneider, B. E., Holst, Jens Juul & Patti, M. E., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 12, p. 4678-4685 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT.
He, Y., Wang, Y., Bullock, J. M., Deacon, Carolyn F., Holst, Jens Juul, Dunning, B. E., Ligueros-Saylan, M. & Foley, J. E., 2007, In: Journal of Clinical Pharmacology. 47, 5, p. 633-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus.
He, Y., Serra, D., Wang, Y., Campestrini, J., Riviere, G., Deacon, Carolyn F., Holst, Jens Juul, Schwartz, S., Nielsen, J. C. & Ligueros-Saylan, M., 2007, In: Clinical Pharmacokinetics. 46, 7, p. 577-88 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects
Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved GLP-1 effects in a diabetic patient with Cushing's disease
Ritzel, R. A., Kleine, N., Holst, Jens Juul, Willms, B., Schmiegel, W. & Nauck, M. A., 2007, In: Experimental and Clinical Endocrinology and Diabetes. 115, 2, p. 146-150 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?
Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Vølund, A., Holst, Jens Juul & Krarup, T., 2007, In: Diabetes. 56, 8, p. 1951-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans
Meier, J. J., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 3, p. E849-E856Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor
Teng, M., Johnson, M. D., Thomas, C., Kiel, D., Lakis, J. N., Kercher, T., Aytes, S., Kostrowicki, J., Bhumralkar, D., Truesdale, L., May, J., Sidelman, U., Kodra, J. T., Jørgensen, A. S., Olesen, P. H., Jong, J. C. D., Madsen, P., Behrens, C., Pettersson, I., Knudsen, L. B. & 2 others, , 2007, In: Bioorganic & Medicinal Chemistry Letters. 17, 19, p. 5472-5478 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sulfonylurea compounds uncouple the glucose dependence of the insulinotropic effect of glucagon-like peptide 1.
de Heer, J. & Holst, Jens Juul, 2007, In: Diabetes. 56, 2, p. 438-43 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suppression of glucagon secretion is lower after oral glucose administration than during intravenous glucose administration in human subjects
Meier, J. J., Deacon, Carolyn F., Schmidt, W. E., Holst, Jens Juul & Nauck, M. A., 2007, In: Diabetologia. 50, 4, p. 806-813 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion
Ouaghlidi, A. E., Rehring, E., Holst, Jens Juul, Schweizer, A., Foley, J., Holmes, D. & Nauck, M. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 11, p. 4165-4171 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients.
Balas, B., Baig, M. R., Watson, C., Dunning, B. E., Ligueros-Saylan, M., Wang, Y., He, Y., Darland, C., Holst, Jens Juul, Deacon, Carolyn F., Cusi, K., Mari, A., Foley, J. E. & DeFronzo, R. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 4, p. 1249-55 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dipeptidyl peptidase-4 inhibitor vildagliptin improves beta-cell function and insulin sensitivity in subjects with impaired fasting glucose
Utzschneider, K. M., Tong, J., Montgomery, B., Udayasankar, J., Gerchman, F., Marcovina, S. M., Watson, C. E., Ligueros-Saylan, M. A., Foley, J. E., Holst, Jens Juul, Deacon, Carolyn F. & Kahn, S. E., 2007, In: Diabetes Care. 31, 1, p. 108-113 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.
Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2007, In: Regulatory Peptides. 144, 1-3, p. 123-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinotrophic peptide, glp-2, counteracts intestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, gefitinib.
Hare, K. J., Hartmann, B., Kissow, Hannelouise, Holst, Jens Juul & Poulsen, Steen Seier, 2007, In: Clinical Cancer Research. 13, 17, p. 5170-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The physiology of glucagon-like peptide 1.
Holst, Jens Juul, 2007, In: Physiological Reviews. 87, 4, p. 1409-39 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The antagonistic metabolite of GLP-1, GLP-1 (9-36)amide, does not influence gastric emptying and hunger sensations in man
Nagell, C. F., Pedersen, J. F. & Holst, Jens Juul, Jan 2007, In: Scandinavian Journal of Gastroenterology. 42, 1, p. 28-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small-molecule agonists for the glucagon-like peptide 1 receptor
Knudsen, L. B., Kiel, D., Teng, M., Behrens, C., Bhumralkar, D., Kodra, J. T., Holst, J. J., Jeppesen, C. B., Johnson, M. D., de Jong, J. C., Jorgensen, A. S., Kercher, T., Kostrowicki, J., Madsen, P., Olesen, P. H., Petersen, J. S., Poulsen, F., Sidelmann, U. G., Sturis, J., Truesdale, L. & 2 others, , 16 Jan 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 3, p. 937-42 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying of glucose solution and associated plasma concentrations of GLP-1, GIP, and PYY before and after fundoplication
Miholic, J., Hoffmann, M., Holst, Jens Juul, Lenglinger, J., Mittlböck, M., Bergmann, H. & Stacher, G., Feb 2007, In: Surgical Endoscopy. 21, 2, p. 309-14 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved GLP-1 effects in a diabetic patient with Cushing's disease
Ritzel, R. A., Kleine, N., Holst, Jens Juul, Willms, B., Schmiegel, W. & Nauck, M. A., Feb 2007, In: Experimental and Clinical Endocrinology and Diabetes. 115, 2, p. 146-50 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women
Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., Mar 2007, In: Bone. 40, 3, p. 723-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus
Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Holst, Jens Juul & Krarup, T., Apr 2007, In: Diabetologia. 50, 4, p. 797-805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus
Knop, F. K., Vilsbøll, Tina, Madsbad, Sten, Holst, Jens Juul, Krarup, T., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Holst, J. M. & Krarup, T., 1 Apr 2007, In: Diabetologia. 50, 4, p. 797-805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes
Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, Cathrine, Jansen-Olesen, I., Chiarelli, F., Holst, Jens Juul, Hougaard, P., Pörksen, S., Holl, R., de Beaufort, C., Gammeltoft, S., Rorsman, P., Mortensen, H. B. & Hansen, L., Jun 2007, In: European Journal of Endocrinology. Supplement. 156, 6, p. 663-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate
Holst, Jens Juul, Hartmann, Bolette, Gottschalck, I. B., Jeppesen, Palle Bekker, Miholic, J. & Henriksen, D. B., Jul 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-20 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteric neural pathways mediate the anti-inflammatory actions of glucagon-like peptide 2
Sigalet, D. L., Wallace, L. E., Holst, Jens Juul, Martin, G. R., Kaji, T., Tanaka, H. & Sharkey, K. A., Jul 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G211-21Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes
Pörksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Ørskov, Cathrine, Holst, Jens Juul, Ploug, K. B., Hougaard, P., Hansen, L. & Mortensen, H. B., Aug 2007, In: The Journal of clinical endocrinology and metabolism. 92, 8, p. 2910-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans
Meier, J. J., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Sep 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 3, p. E849-56Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion
Cani, P. D., Holst, Jens Juul, Drucker, D. J., Delzenne, N. M., Thorens, B., Burcelin, R. & Knauf, C., 30 Sep 2007, In: Molecular and Cellular Endocrinology. 276, 1-2, p. 18-23 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The alpha cell expresses glucagon-like peptide-2 receptors and glucagon-like peptide-2 stimulates glucagon secretion from the rat pancreas
de Heer, J., Pedersen, J., Ørskov, Cathrine & Holst, Jens Juul, Oct 2007, In: Diabetologia. 50, 10, p. 2135-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 (GLP-1) suppresses ghrelin levels in humans via increased insulin secretion
Hagemann, D., Holst, Jens Juul, Gethmann, A., Banasch, M., Schmidt, W. E. & Meier, J. J., 4 Oct 2007, In: Regulatory Peptides. 143, 1-3, p. 64-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion
El-Ouaghlidi, A., Rehring, E., Holst, Jens Juul, Schweizer, A., Foley, J., Holmes, D. & Nauck, M. A., Nov 2007, In: The Journal of clinical endocrinology and metabolism. 92, 11, p. 4165-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet
McClean, P. L., Irwin, N., Cassidy, R. S., Holst, Jens Juul, Gault, V. A. & Flatt, P. R., Dec 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 6, p. E1746-55Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms
Schäfer, S. A., Tschritter, O., Machicao, F., Thamer, C., Stefan, N., Gallwitz, B., Holst, Jens Juul, Dekker, J. M., 't Hart, L. M., t'Hart, L. M., Nijpels, G., van Haeften, T. W., Häring, H. U. & Fritsche, A., Dec 2007, In: Diabetologia. 50, 12, p. 2443-50 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal
Goldfine, A. B., Mun, E. C., Devine, E., Bernier, R., Baz-Hecht, M., Jones, D. B., Schneider, B. E., Holst, Jens Juul & Patti, M. E., Dec 2007, In: The Journal of clinical endocrinology and metabolism. 92, 12, p. 4678-85 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
Angiotensin-converting enzyme activity and cognitive impairment during hypoglycaemia in healthy humans
Pedersen-Bjergaard, Ulrik, Thomsen, Carsten Eckhart, Høgenhaven, H., Smed, A., Kjaer, T. W., Holst, Jens Juul, Dela, Flemming, Hilsted, Linda, Frandsen, E., Pramming, S. & Thorsteinsson, B., 2008, In: Journal of the Renin-Angiotensin-Aldosterone System. 9, 1, p. 37-48 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Appetitregulering: et komplekst system
Sloth, B. & Holst, Jens Juul, 2008, In: Perspektiv : tidsskrift om ernæring. 1, p. 4-8 5 p.Research output: Contribution to journal › Journal article › Communication
- Published
Appetitregulering: et komplekst system
Sloth, B. & Holst, Jens Juul, 2008, In: Perspektiv. 1, 8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of the effects on insulin resistance and glucose tolerance of 6-mo high-monosaturated-fat, low-fat, and control diets
Due, A. P., Larsen, T. M., Hermansen, K., Stender, Steen, Holst, Jens Juul, Toubro, S., Martinussen, Torben & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 4, p. 855-862 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of the effects on insulin resistance and glucose tolerance of 6-mo high-monounsaturated-fat, low-fat, and control diets
Due, A. P., Larsen, T. M., Hermansen, K., Stender, Steen, Holst, Jens Juul, Toubro, S., Martinussen, Torben & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 4, p. 855-862 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes
Deacon, Carolyn F., Carr, R. D. & Holst, Jens Juul, 2008, In: Frontiers in Bioscience. 13, p. 1780-94 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determinants of glycemic charges in normoglycemic individuals
Faerch, K., Vaag, Allan, Holst, Jens Juul, Hansen, T., Glumer, C. & Borch-Johnsen, K., 2008, In: Diabetes. Suppl. 1, p. A659-A659 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Effect of Vildagliptin on Glucagon Concentration During Meals in Patients with Type 1 Diabetes
Foley, J. E., Ligueros-Saylan, M., He, Y. L., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., 2008, In: Hormone and Metabolic Research. 40, 10, p. 727-730 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of intravenous glucagon-like peptide-1 on glucose control and hemodynamics after coronary artery bypass surgery in patients with type 2 diabetes
Mussig, K., Oncu, A., Lindauer, P., Heininger, A., Aebert, H., Unertl, K., Ziemer, G., Haring, H. U., Gallwitz, B. & Holst, Jens Juul, 2008, In: Journal of the American College of Cardiology. 102, 5, p. 646-647 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of the dipeptidyl peptidase-IV inhibitor vildagliptin on incretin hormones, islet function, and postprandial glycemia in subjects with impaired glucose tolerance.
Rosenstock, J., Foley, J. E., Rendell, M., Landin-Olsson, M., Holst, Jens Juul, Deacon, Carolyn F., Rochotte, E. & Baron, M. A., 2008, In: Diabetes Care. 31, 1, p. 30-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome
Gottschalck, I. B., Jeppesen, Palle Bekker, Hartmann, Bolette, Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 11, p. 1304-10 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of treatment with glucagon-like peptide-2 on bone resorption in colectomized patients with distal ileostomy or jejunostomy and short-bowel syndrome
Gottschalck, I. B., Jeppesen, Palle Bekker, Hartmann, B., Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 11, p. 1304-1310 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteral nutrients potentiate the intestinotrophic action of glucagon-like peptide-2 in association with increased insulin-like growth factor-I responses in rats.
Liu, X., Murali, S. G., Holst, Jens Juul & Ney, D. M., 2008, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. p. 295:R1794-1802Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exogenous glucagon-like peptide-2 (GLP-2) augments GLP-2 receptor mRNA and maintains proglucagon mRNA levels in resected rats
Koopmann, M. C., Nelson, D. W., Murali, S. G., Liu, X. W., Brownfield, M. S., Holst, Jens Juul & Ney, D. M., 2008, In: Journal of Parenteral and Enteral Nutrition. 32, 3, p. 254-265 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
Højberg, P. V., Vilsbøll, Tina, Rabøl, R., Knop, Filip Krag, Bache, M., Krarup, T., Holst, Jens Juul & Madsbad, Sten, 2008, In: Diabetologia. 52, 2, p. 199-207 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate
Amin, H., Holst, Jens Juul, Hartmann, B., Wallace, L., Wright, J. & Sigalet, D. L., 2008, In: Pediatrics. 121, 1, p. E180-E186 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome
Hellstrom, P. M., Naslund, E., Edholm, T., Schmidt, P. T., Kristensen, J., Theodorsson, E., Holst, Jens Juul & Efendic, S., 2008, In: Neurogastroenterology and Motility. 20, 6, p. 649-659 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1: physiological effects and potential therapeutic applications
Aaboe, K., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Aaboe, K., Krarup, T., Madsbad, Sten & Holst, J. J., 2008, In: Diabetic Medicine. 10, 11, p. 994-1003 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 administration results in increased proliferation but paradoxically an adverse outcome in a juvenile piglet model of short bowel syndrome
Pereira-Fantini, P. M., Nagy, T. S., Thomas, S. L., Taylor, R. G., Sourial, M., Paris, M. C. J., Holst, J. J., Fuller, P. J., Bines, J. E. & Holst, Jens Juul, 2008, In: Journal of Pediatric Gastroenterology and Nutrition. 46, 1, p. 20-28 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials
Madsbad, Sten, Krarup, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Deacon, C. F. & Holst, J. J., 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 inhibits blood-brain glucose transfer in humans
Lerche, S., Brock, B., Rungby, J., Bøtker, H. E., Møller, N., Rodell, A., Bibby, B. M., Holst, Jens Juul, Schmitz, O. & Gjedde, Albert, 2008, In: Diabetes. 57, 2, p. 325-31 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas
de, H. J., Rasmussen, C., Coy, D. H. & Holst, Jens Juul, 2008, In: Diabetologia. 51, 12, p. 2263-2270 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1, glucose homeostasis and diabetes.
Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, 2008, In: Trends in Molecular Medicine. 14, 4, p. 161-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 increases mesenteric blood flow in humans
Bremholm, L., Hornum, Mads, Henriksen, B. M., Larsen, S. & Holst, Jens Juul, 2008, In: Scandinavian Journal of Gastroenterology. 44, 3, p. 314-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucokinase, the pancreatic glucose sensor, is not the gut glucose sensor
Murphy, R., Tura, A., Clark, P. M., Holst, Jens Juul, Mari, A. & Hattersley, A. T., 2008, In: Diabetologia. 52, 1, p. 154-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut transit is associated with gastrointestinal symptoms and gut hormone profile in patients with cirrhosis
Kalaitzakis, E., Sadik, R., Holst, Jens Juul, Ohman, L. & Björnsson, E., 2008, In: Clinical Gastroenterology and Hepatology. 7, 3, p. 346-52 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired fasting glycaemia vs impaired glucose tolerance: similar impairment of pancreatic alpha and beta cell function but differential roles of incretin hormones and insulin action
Faerch, K., Vaag, Allan, Holst, Jens Juul, Glümer, C., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2008, In: Diabetologia. 51, 5, p. 853-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast
Nilsson, A. C., Ostman, E. M., Holst, Jens Juul & Bjorck, I. M., 2008, In: Journal of Nutrition. 138, 4, p. 732-739 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study
Laakso, M., Zilinskaite, J., Hansen, Torben, Boesgaard, T. W., Vänttinen, M., Stancáková, A., Jansson, P., Pellmé, F., Kuulasmaa, T., Hribal, M. L., Sesti, G., Stefan, N., Fritsche, A., Häring, H., Pedersen, Oluf Borbye, Smith, U., EUGENE2 Consortium, E. C. & Holst, Jens Juul, 2008, In: Diabetologia. 51, 3, p. 502-11 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin-like growth factor I and glucagon-like peptide-2 responses to fasting followed by controlled or ad libitum refeeding in rats
Nelson, D. W., Murali, S. G., Liu, X. W., Koopmann, M. C., Holst, Jens Juul & Ney, D. M., 2008, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 294, 4, p. R1175-R1184Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study
Robertson, M. A., Sigalet, D. L., Holst, Jens Juul, Meddings, J. B., Wood, J. & Sharkey, K. A., 2008, In: Journal of Autism and Developmental Disorders. 38, 6, p. 1066-1071 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meal-induced compositional changes in blood and saliva in persons with bulimia nervosa
Dynesen, A. W., Jensen, A. B., Astrup, A., Petersson, B., Holst, Jens Juul & Nauntofte, B., 2008, In: American Journal of Clinical Nutrition. 87, 1, p. 12-22 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurements Inhibition of DPP-4 evokes pancreatic and extra-pancreatic mechanisms that improve glucose homeostasis in type 2 diabetes mellitus.
Azuma, K., Radikova, Z., Mancino, J., Toledo, F., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D. & Kelley, D., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, p. 459-463Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Natural history of insulin sensitivity and insulin secretion in the progression from normal glucose tolerance to impaired fasting glycemia and impaired glucose tolerance: the Inter99 study
Faerch, K., Vaag, Allan, Holst, Jens Juul, Hansen, Torben, Jørgensen, T. & Borch-Johnsen, K., 2008, In: Diabetes Care. 32, 3, p. 439-44 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No increased risk of hypoglycaemic episodes during 48 h of subcutaneous glucagon-like-peptide-1 administration in fasting healthy subjects
Lerche, S., Soendergaard, L., Rungby, J., Moeller, N., Holst, Jens Juul, Schmitz, O. E. & Brock, B., 2008, In: Clinical Endocrinology. 71, 4, p. 500-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects
Greenfield, J. R., Farooqi, I. S., Keogh, J. M., Henning, E., Habib, A. M., Blackwood, A., Reimann, F., Holst, Jens Juul & Gribble, F. M., 2008, In: American Journal of Clinical Nutrition. 89, 1, p. 106-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Orlistat accelerates gastric emptying and attenuates GIP release in healthy subjects
Enç, F. Y., Ones, T., Akin, H. L., Dede, F., Turoglu, H. T., Ulfer, G., Bekiroglu, N., Haklar, G., Rehfeld, Jens Frederik, Holst, Jens Juul, Ulusoy, N. B. & Imeryüz, N., 2008, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 296, 3, p. G482-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations
Ellrichmann, M., Kapelle, M., Ritter, P. R., Holst, Jens Juul, Herzig, K. H., Schmidt, W. E., Schmitz, F. & Meier, J. J., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 3995-3998 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overconsumption and obesity: Peptides and susceptibility to weight gain
Blundell, J. E., Levin, F., King, N. A., Barkeling, B., Gustafson, T., Hellstrom, P. M., Holst, Jens Juul & Naslund, E., 2008, In: Regulatory Peptides. 149, 1-3, p. 32-38 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overview of incretin hormones.
Holst, Jens Juul & Lasalle, J., 2008, In: Journal of Family Practice. 57, 9, p. 53-59Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma glucagon-like peptide 1 and peptide YY levels are not altered in symptomatic fructose-sorbitol malabsorption.
Valeur, J., Øines, E., Morken, M. H., Holst, Jens Juul & Berstad, A., 2008, In: Scandinavian Journal of Gastroenterology. 43, 10, p. 1212-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictors of incretin concentrations in subjects with normal, impaired, and diabetic glucose tolerance
Vollmer, K., Holst, Jens Juul, Baher, B., Ellrichmann, M., Nauck, M. A., Schmidt, W. E. & Meier, J. J., 2008, In: Diabetes. 57, 3, p. 678-687 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Progression from normal glucose tolerance to impaired fasting glycaemia and impaired glucose tolerance: differential roles of insulin resistance and beta cell dysfunction
Faerch, K., Vaag, Allan, Holst, Jens Juul, Pedersen, O., Glumer, C. & Borch-Johnsen, K., 2008, In: Diabetologia. 51, Suppl. 1, p. S85-S86Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract
Gottschalck, I. B., Jeppesen, Palle Bekker, Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 8, p. 929-937 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replacing SUs with incretin-based therapies for type 2 diabetes mellitus: Challenges and feasibility
Knop, F. K., Holst, Jens Juul & Vilsbøll, Tina, 2008, In: IDrugs. The Investigational Drugs Journal. 11, 7, p. 497-501 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients
Muscelli, E., Mari, A., Casolaro, A., Camastra, S., Seghieri, G., Gastaldelli, A., Holst, Jens Juul & Ferrannini, E., 2008, In: Diabetes. 57, 5, p. 1340-1348 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temporal changes in the intestinal growth promoting effects of glucagon-like peptide 2 following intestinal resection
Kaji, T., Tanaka, H., Redstone, H., Wallace, L. E., Holst, Jens Juul & Sigalet, D. L., 2008, In: Journal of Surgical Research. 152, 2, p. 271-80 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Relationship between Glucagon-Like Peptide 2 and Feeding Intolerance in Preterm Infants.
Ozer, E. A., Holst, Jens Juul, Duman, N., Kumral, A. & Ozkan, H., 2008, In: Journal of Tropical Pediatrics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of a high monounsaturated fatty acid, low glycemic index diet and a low fat diet on satiety, appetite regulatory hormones and glucose metabolism during a 6 mo weight maintenance period
Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: International Journal of Obesity. 32, Suppl. 1, p. S204 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
The effect of a high-MUFA, low-glycaemic index diet and a low-fat diet on appetite and glucose metabolism during a 6-month weight maintenance period
Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: British Journal of Nutrition. 101, 12, p. 1846-1858 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of salatrim, a low-calorie modified triacylglycerol, on appetite and energy intake
Sørensen, L. B., Cueto, H. T., Andersen, M. T., Bitz, C., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 5, p. 1163-1169 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat
Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., Heuval, E. D. & Sigalet, D. L., 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-145 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin system and its role in type 2 diabetes mellitus
Holst, Jens Juul, Vilsbøll, Tina & Deacon, Carolyn F., 2008, In: Molecular and Cellular Endocrinology. 297, 1-2, p. 127-136 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The physiology and pharmacology of incretins in type 2 diabetes mellitus
Holst, Jens Juul, 2008, In: Diabetes, Obesity and Metabolism. 10, Suppl. 3, p. 14-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate
Amin, H., Holst, Jens Juul, Hartmann, Bolette, Wallace, L., Wright, J. & Sigalet, D. L., Jan 2008, In: Pediatrics. 121, 1, p. e180-6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 administration results in increased proliferation but paradoxically an adverse outcome in a juvenile piglet model of short bowel syndrome
Pereira-Fantini, P. M., Nagy, E. S., Thomas, S. L., Taylor, R. G., Sourial, M., Paris, M. C. J., Holst, Jens Juul, Fuller, P. J. & Bines, J. E., Jan 2008, In: Journal of Pediatric Gastroenterology and Nutrition. 46, 1, p. 20-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Including indigestible carbohydrates in the evening meal of healthy subjects improves glucose tolerance, lowers inflammatory markers, and increases satiety after a subsequent standardized breakfast
Nilsson, A. C., Ostman, E. M., Holst, Jens Juul & Björck, I. M. E., Apr 2008, In: Journal of Nutrition. 138, 4, p. 732-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin-like growth factor I and glucagon-like peptide-2 responses to fasting followed by controlled or ad libitum refeeding in rats
Nelson, D. W., Murali, S. G., Liu, X., Koopmann, M. C., Holst, Jens Juul & Ney, D. M., Apr 2008, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 294, 4, p. R1175-84Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes
Højberg, P. V., Zander, M., Vilsbøll, T., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, 1 Apr 2008, In: Diabetologia. 51, 4, p. 632-640 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exogenous glucagon-like peptide-2 (GLP-2) augments GLP-2 receptor mRNA and maintains proglucagon mRNA levels in resected rats
Koopmann, M. C., Nelson, D. W., Murali, S. G., Liu, X., Brownfield, M. S., Holst, Jens Juul & Ney, D. M., 30 Apr 2008, In: Journal of Parenteral and Enteral Nutrition. 32, 3, p. 254-65 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients
Muscelli, E., Mari, A., Casolaro, A., Camastra, S., Seghieri, G., Gastaldelli, A., Holst, Jens Juul & Ferrannini, E., May 2008, In: Diabetes. 57, 5, p. 1340-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome
Hellström, P. M., Näslund, E., Edholm, T., Schmidt, P. T., Kristensen, J., Theodorsson, E., Holst, Jens Juul & Efendic, S., Jun 2008, In: Neurogastroenterology and Motility Online. 20, 6, p. 649-59 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials
Madsbad, Sten, Krarup, T., Deacon, Carolyn F. & Holst, Jens Juul, Jul 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study
Robertson, M. A., Sigalet, D. L., Holst, Jens Juul, Meddings, J. B., Wood, J. & Sharkey, K. A., Jul 2008, In: Journal of Autism and Developmental Disorders. 38, 6, p. 1066-71 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replacing SUs with incretin-based therapies for type 2 diabetes mellitus: challenges and feasibility
Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, T., Jul 2008, In: I Drugs: the Investigational Drugs Journal. 11, 7, p. 497-501 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract
Gottschalck, I. B., Jeppesen, Palle Bekker, Holst, Jens Juul & Henriksen, D. B., Aug 2008, In: Scandinavian Journal of Gastroenterology. 43, 8, p. 929-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overconsumption and obesity: peptides and susceptibility to weight gain
Blundell, J. E., Levin, F., King, N. A., Barkeling, B., Gustafsson, T., Gustafson, T., Hellstrom, P. M., Holst, Jens Juul & Naslund, E., 7 Aug 2008, In: Regulatory Peptides. 149, 1-3, p. 32-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of intravenous glucagon-like peptide-1 on glucose control and hemodynamics after coronary artery bypass surgery in patients with type 2 diabetes
Müssig, K., Oncü, A., Lindauer, P., Heininger, A., Aebert, H., Unertl, K., Ziemer, G., Häring, H., Holst, Jens Juul & Gallwitz, B., 1 Sep 2008, In: American Journal of Cardiology. 102, 5, p. 646-7 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes
Foley, J. E., Ligueros-Saylan, M., He, Y., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., Oct 2008, In: Hormone and Metabolic Research. Supplement. 40, 10, p. 727-30 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations
Ellrichmann, M., Kapelle, M., Ritter, P. R., Holst, Jens Juul, Herzig, K., Schmidt, W. E., Schmitz, F. & Meier, J. J., Oct 2008, In: The Journal of clinical endocrinology and metabolism. 93, 10, p. 3995-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat
Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., de Heuval, E. & Sigalet, D. L., 31 Oct 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-45 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes
Højberg, P. V., Vilsbøll, T., Zander, M., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, Nov 2008, In: Diabetic Medicine Online. 25, 11, p. 1268-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1: physiological effects and potential therapeutic applications
Aaboe, K., Krarup, T., Madsbad, Sten & Holst, Jens Juul, Nov 2008, In: Diabetes, Obesity and Metabolism Online. 10, 11, p. 994-1003 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas
de Heer, J., Rasmussen, C., Coy, D. H. & Holst, Jens Juul, Dec 2008, In: Diabetologia. 51, 12, p. 2263-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion
Müssig, K., Staiger, H., Machicao, F., Kirchhoff, K., Guthoff, M., Schäfer, S. A., Kantartzis, K., Silbernagel, G., Stefan, N., Holst, Jens Juul, Gallwitz, B., Häring, H. & Fritsche, A., 2009, In: Diabetes. 58, 7, p. 1715-20 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circadian rhythms of GIP and GLP1 in glucose-tolerant and in type 2 diabetic patients after biliopancreatic diversion
Mingrone, G., Nolfe, G., Gissey, G. C., Iaconelli, A., Leccesi, L., Guidone, C., Nanni, G. & Holst, Jens Juul, 2009, In: Diabetologia. 52, 5, p. 873-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cognitive performance, symptoms and counter-regulation during hypoglycaemia in patients with type 1 diabetes and high or low renin-angiotensin system activity
Høi-Hansen, T., Pedersen-Bjergaard, U., Andersen, R. D., Kristensen, P. L., Thomsen, C., Kjaer, T., Høgenhaven, H., Smed, A., Holst, J. J., Dela, F., Boomsma, F., Thorsteinsson, B., Høi-Hansen, T., Pedersen-Bjergaard, U., Andersen, R. D., Kristensen, P. L., Thomsen, C., Kjaer, T., Høgenhaven, H., Smed, A. & 4 others, , 2009, In: Journal of the Renin-Angiotensin-Aldosterone System. 10, 4, p. 216-29 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colesevelam improves insulin resistance in a diet-induced obesity (F-DIO) rat model by increasing the release of GLP-1
Shang, Q., Saumoy, M., Holst, Jens Juul, Salen, G. & Xu, G., 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 298, 3, p. G419-24Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colonic GLP-2 is not sufficient to promote jejunal adaptation in a PN-dependent rat model of human short bowel syndrome
Koopmann, M. C., Liu, X., Boehler, C. J., Murali, S. G., Holst, Jens Juul & Ney, D. M., 2009, In: Journal of Parenteral and Enteral Nutrition. 33, 6, p. 629-38; discussion 638-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative effect of orally administered sodium butyrate before or after weaning on growth and several indices of gastrointestinal biology of piglets
Le Gall, M., Gallois, M., Sève, B., Louveau, I., Holst, Jens Juul, Oswald, I. P., Lallès, J. & Guilloteau, P., 2009, In: British Journal of Nutrition. 102, 9, p. 1285-96 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DPP-4 inhibition – advances in our understanding of diabetes management
Deacon, Carolyn F. & Holst, Jens Juul, 2009, In: European Endocrinology. 4, p. 47-49Research output: Contribution to journal › Review › Research
- Published
Differential effect of PYY1-36 and PYY3-36 on gastric emptying in man
Witte, A., Grybäck, P., Holst, Jens Juul, Hilsted, Linda, Hellström, P. M., Jacobsson, H. & Schmidt, P. T., 2009, In: Regulatory Peptides. 158, 1-3, p. 57-62 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of protein quality on postprandial lipemia in response to a fat-rich meal in type 2 diabetes: comparison of whey, casein, gluten, and cod protein
Mortensen, L. S., Hartvigsen, M. L., Brader, L. J., Astrup, A., Schrezenmeir, J., Holst, Jens Juul, Thomsen, C. & Hermansen, K., 2009, In: American Journal of Clinical Nutrition. 90, 1, p. 41-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissociated incretin response to oral glucose at 1 year after restrictive vs. malabsorptive bariatric surgery
Guldstrand, M., Ahrén, B., Näslund, E., Holst, Jens Juul & Adamson, U., 2009, In: Diabetes, Obesity and Metabolism. 11, 11, p. 1027-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of sodium butyrate supplementation in milk replacer and starter diet on rumen development in calves
Gorka, P., Kowalski, Z. M., Pietrzak, P., Kotunia, A., Kiljanczyk, R., Flaga, J., Holst, Jens Juul, Guilloteau, P. & Zabielski, R., 2009, In: Journal of Physiology and Pharmacology. 60 Suppl 3, p. 47-53 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of viscosity on appetite and gastro-intestinal hormones
Zijlstra, N., Mars, M., de Wijk, R. A., Westerterp-Plantenga, M. S., Holst, Jens Juul & de Graaf, C., 2009, In: Physiology & Behavior. 97, 1, p. 68-75 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and ghrelin concentrations in healthy subjects
Hlebowicz, J., Hlebowicz, A., Lindstedt, S., Björgell, O., Höglund, P., Holst, Jens Juul, Darwiche, G. & Almér, L., 2009, In: American Journal of Clinical Nutrition. 89, 3, p. 815-21 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of meal size and composition on incretin, alpha-cell, and beta-cell responses
Rijkelijkhuizen, J. M., McQuarrie, K., Girman, C. J., Stein, P. P., Mari, A., Holst, Jens Juul, Nijpels, G. & Dekker, J. M., 2009, In: Metabolism - Clinical and Experimental.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD
Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2009, In: Bone. 45, 5, p. 833-42 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction
Holst, Birgitte, Egerod, Kristoffer Lihme, Jin, C., Petersen, P. S., Østergaard, M. V., Hald, J., Sprinkel, A. M. E., Størling, J., Mandrup-Poulsen, Thomas, Holst, Jens Juul, Thams, P., Orskov, C., Wierup, N., Sundler, F., Madsen, O. D. & Schwartz, Thue W., 2009, In: Endocrinology. 150, 6, p. 2577-85 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 receptor agonists: targeting both hyperglycaemia and disease processes in diabetes
Holst, Jens Juul & Seino, Y., 2009, In: Diabetes Research and Clinical Practice. 85, 1, p. 1-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans
Vollmer, K., Gardiwal, H., Menge, B. A., Goetze, O., Deacon, Carolyn F., Schmidt, W. E., Holst, Jens Juul & Meier, J. J., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1379-85 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunoassays for the incretin hormones GIP and GLP-1
Deacon, Carolyn F. & Holst, Jens Juul, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 425-32 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired glucose-induced glucagon suppression after partial pancreatectomy
Schrader, H., Menge, B. A., Breuer, T. G. K., Ritter, P. R., Uhl, W., Schmidt, W. E., Holst, Jens Juul & Meier, J. J., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 8, p. 2857-63 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved tolerance to sequential glucose loading (Staub-Traugott effect): size and mechanisms
Bonuccelli, S., Muscelli, E., Gastaldelli, A., Barsotti, E., Astiarraga, B. D., Holst, Jens Juul, Mari, A. & Ferrannini, E., 2009, In: American Journal of Physiology: Endocrinology and Metabolism. 297, 2, p. E532-7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity, and treatment with metformin
phk294, phk294, Nilas, L., Madsbad, Sten & Holst, Jens Juul, 2009, In: Metabolism - Clinical and Experimental. 58, 5, p. 586-593Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormones and diabetes mellitus
Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F. & Holst, Jens Juul, 2009, Therapeutic Strategies in Diabetes. Stehouwer, C. D. A. & Schaper, N. (eds.). Oxford: Clinical Publishing, p. 99-114Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Incretin-based therapy of type 2 diabetes mellitus
Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2009, In: Current Protein and Peptide Science. 10, 1, p. 46-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats
Simonsen, L., Pilgaard, S., Carr, R. D., Kanstrup, A. B., Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Hormone and Metabolic Research. 41, 11, p. 851-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes
Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kirurgisk behandling af type 2-diabetes
Olesen, S. C., Hansen, D. L., Almdal, Thomas Peter, Bendtsen, Flemming, Nordgaard, I., Hvolris, L. E., Holst, Jens Juul, Naver, L. & Madsbad, Sten, 2009, In: Ugeskrift for læger. 171, 8, p. 615-7 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lixisenatide, a novel GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus
Christensen, M., Knop, Filip Krag, Holst, Jens Juul & Vilsboll, T., 2009, In: IDrugs. The Investigational Drugs Journal. 12, 8, p. 503-13 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats
Simonsen, L., Pilgaard, S., Orskov, C., Hartmann, Bolette, Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Diabetes, Obesity and Metabolism. 11, 9, p. 884-90 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of Gastric Emptying Disturbances in Chronic and Acute Inflammation of the Distal Gastrointestinal Tract
Keller, J., Beglinger, C., Holst, Jens Juul, Andresen, V. & Layer, P., 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutritional effects of the serial transverse enteroplasty procedure in experimental short bowel syndrome
Kaji, T., Tanaka, H., Wallace, L. E., Kravarusic, D., Holst, Jens Juul & Sigalet, D. L., 2009, In: European Journal of Pediatric Surgery. Supplement. 44, 8, p. 1552-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass
Gelling, R. W., Vuguin, P. M., Du, X. Q., Cui, L., Rømer, J., Pederson, R. A., Leiser, M., Sørensen, H., Holst, Jens Juul, Fledelius, C., Johansen, P. B., Fleischer, N., McIntosh, C. H. S., Nishimura, E. & Charron, M. J., 2009, In: American Journal of Physiology: Endocrinology and Metabolism. 297, 3, p. E695-707Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathophysiology and aetiology of impaired fasting glycaemia and impaired glucose tolerance: does it matter for prevention and treatment of type 2 diabetes?
Faerch, K., Borch-Johnsen, K., Holst, Jens Juul & Vaag, Allan, 2009, In: Diabetologia. 52, 9, p. 1714-23 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus
Müssig, K., Staiger, H., Machicao, F., Machann, J., Schick, F., Schäfer, S. A., Claussen, C. D., Holst, Jens Juul, Gallwitz, B., Stefan, N., Fritsche, A. & Häring, H., 2009, In: Metabolism - Clinical and Experimental. 58, 12, p. 1809-11 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus
Hare, K. J., Knop, Filip Krag, Asmar, M., Madsbad, Sten, Deacon, Carolyn F., Holst, Jens Juul & Vilsbøll, Tina, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4679-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat
Bucinskaite, V., Tolessa, T., Pedersen, J., Rydqvist, B., Zerihun, L., Holst, Jens Juul & Hellström, P. M., 2009, In: Neurogastroenterology and Motility. 21, 9, p. 978-e78Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced plasma levels of glucagon-like peptide-1 in elderly men are associated with impaired glucose tolerance but not with coronary heart disease
Nathanson, D., Zethelius, B., Berne, C., Holst, Jens Juul, Sjöholm, A. & Nyström, T., 2009, In: Diabetologia. 53, 2, p. 277-80 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Remission af type 2-diabetes efter gastric bypass-kirurgi: et medicinsk mysterium?
Jacobsen, S., Hansen, D. L., Worm, Dorte, Madsbad, Sten, Hvolris, L. E., Naver, L. P. S. & Holst, Jens Juul, 2009, In: Behandlerbladet. p. 20-29 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
Deacon, Carolyn F. & Holst, Jens Juul, 2009, In: Advances in Therapy. 26, 5, p. 488-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism
Patti, M., Houten, S. M., Bianco, A. C., Bernier, R., Larsen, P. R., Holst, Jens Juul, Badman, M. K., Maratos-Flier, E., Mun, E. C., Pihlajamaki, J., Auwerx, J. & Goldfine, A. B., 2009, In: Obesity. 17, 9, p. 1671-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short bowel patients treated for two years with glucagon-like Peptide 2: effects on intestinal morphology and absorption, renal function, bone and body composition, and muscle function
Jeppesen, Pia, Lund, P., Gottschalck, I. B., Nielsen, H. B., Holst, Jens Juul, Mortensen, J., Poulsen, S. S., Quistorff, B. & Mortensen, P. B., 2009, In: Gastroenterology Research and Practice. 2009, p. 616054Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short bowel patients treated for two years with glucagon-like peptide 2 (GLP-2): compliance, safety, and effects on quality of life
Jeppesen, Palle Bekker, Lund, P., Gottschalck, I. B., Nielsen, H. B., Holst, Jens Juul, Mortensen, J., Poulsen, S. S., Quistorff, B. & Mortensen, P. B., 2009, In: Gastroenterology Research and Practice. 2009, p. 425759Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term treatment with olanzapine does not modulate gut hormone secretion: olanzapine disintegrating versus standard tablets
Vidarsdottir, S., Roelfsema, F., Streefland, T., Holst, Jens Juul, Rehfeld, Jens Frederik & Pijl, H., 2009, In: European Journal of Endocrinology. 162, 1, p. 75-83 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of dietary fibre type on satiety-related hormones and voluntary food intake in dogs
Bosch, G., Verbrugghe, A., Hesta, M., Holst, Jens Juul, van der Poel, A. F. B., Janssens, G. P. J. & Hendriks, W. H., 2009, In: British Journal of Nutrition. 102, 2, p. 318-25 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The spectrum of antidiabetic actions of GLP-1 in patients with diabetes
Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 453-62 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 2 diabetes with glucagon-like peptide-1 receptor agonists
Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, 2009, In: International Journal of Clinical Practice. 63, 8, p. 1154-60 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial
Aaboe, K., Knop, F. K., Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2009, In: Diabetologia. p. 748Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Whey protein potentiates the intestinotrophic action of glucagon-like peptide-2 in parenterally fed rats
Liu, X., Murali, S. G., Holst, Jens Juul & Ney, D. M., 2009, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 297, 5, p. R1554-62Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes of cognition and regional cerebral activity during acute hypoglycemia in normal subjects: A H2 15O positron emission tomographic study
Bie-Olsen, L. G., Kjaer, T. W., Pedersen-Bjergaard, Ulrik, Lonsdale, M. N., Holst, Jens Juul, Law, Ian & Thorsteinsson, B., Jun 2009, In: Journal of Neuroscience Research. 87, 8, p. 1922-1928 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of gastric emptying disturbances in chronic and acute inflammation of the distal gastrointestinal tract
Keller, J., Beglinger, C., Holst, Jens Juul, Andresen, V. & Layer, P., Nov 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 297, 5, p. G861-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists
Kielgast, U., Holst, Jens Juul & Madsbad, Sten, Nov 2009, In: Current Diabetes Reviews. 5, 4, p. 266-75 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cognitive performance, symptoms and counter-regulation during hypoglycaemia in patients with type 1 diabetes and high or low renin-angiotensin system activity
Høi-Hansen, T., Pedersen-Bjergaard, Ulrik, Andersen, R. D., Kristensen, Peter Lommer, Thomsen, C., Kjaer, T., Høgenhaven, H., Smed, A., Holst, Jens Juul, Dela, Flemming, Boomsma, F. & Thorsteinsson, B., Dec 2009, In: Journal of the Renin-Angiotensin-Aldosterone System. 10, 4, p. 216-29 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Acute effects of casein on postprandial lipemia and incretin responses in type 2 diabetic subjects
Brader, L. J., Holm, L., Mortensen, L., Thomsen, C., Astrup, A., Holst, Jens Juul, Vrese, M. D., Schrezenmeir, J. & Hermansen, K., 2010, In: Nutrition, Metabolism & Cardiovascular Diseases. 20, 2, p. 101-109 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of glucagon-like peptide-1 on alpha- and beta-cell function in C-peptide-negative type 1 diabetic patients
Kielgast, U., Asmar, M., Madsbad, Sten & Holst, Jens Juul, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 5, p. 2492-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Postprandial Response of Glucagon-Like Peptide-2 in Patients with Chronic Pancreatitis and Pancreatic Exocrine Insufficiency
Hornum, Mads, Pedersen, J. F., Larsen, S., Olsen, O., Holst, Jens Juul & Knop, Filip Krag, 2010, In: Pancreatology. 10, 2-3, p. 201-207 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulinets vej ind i det danske samfund
Larsen, Erik Hviid & Holst, Jens Juul, 2010, Det fremmede som historisk drivkraft. Danmark efter 1742: Et festskrift til Hendes Majestæt Dronning Margrethe II ved 70-års-fødselsdagen den 16. april 2010. Nielsen, M. A. (ed.). København: Det Kongelige Danske Videnskabernes Selskab, p. 85-94Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes
Deacon, Carolyn F. & Holst, Jens Juul, 2010, In: Expert Opinion on Investigational Drugs. 19, 1, p. 133-140 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans
Asmar, M., Tangaa, W., Madsbad, Sten, Hare, K., Astrup, A., Flint, A., Bülow, J. & Holst, Jens Juul, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 3, p. E614-21 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes
Asmar, M., Højberg, P. V., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-80 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic ß-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes
Asmar, M., Højberg, P., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-180 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion: a case report
Dirksen, C., Hansen, D. L., Madsbad, Sten, Hvolris, L. E., Naver, L. S., Holst, Jens Juul & Worm, Dorte, 2010, In: Diabetes Care. 33, 2, p. 375-377Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men
Carr, R. D., Larsen, M. O., Jelic, K., Lindgren, O., Vikman, J., Holst, Jens Juul, Deacon, Carolyn F. & Ahrén, B., 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 872-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The T-allele of TCF7L2 rs7903146 associates with a reduced compensation of insulin secretion for insulin resistance induced by 9 days of bed rest
Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Hansen, T., Pedersen, Oluf Borbye, van Hall, Gerrit, Holst, Jens Juul, Stallknecht, Bente Merete, Dela, Flemming & Vaag, A., 2010, In: Diabetes. 59, 4, p. 836-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of DPP-4 inhibition with sitagliptin on incretin secretion and on fasting and postprandial glucose turnover in subjects with impaired fasting glucose
Bock, G., Man, C. D., Micheletto, F., Basu, R., Rn, P. D. G., Laugen, J., Deacon, Carolyn F., Holst, Jens Juul, Toffolo, G., Cobelli, C., Rizza, R. A. & Vella, A., 2010, In: Clinical Endocrinology. 73, p. 189-196Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus
Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes
Deacon, Carolyn F. & Holst, Jens Juul, Jan 2010, In: Expert Opinion on Investigational Drugs. 19, 1, p. 133-40 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Little enhancement of meal-induced GLP-1 secretion in Japanese: Comparison of type 2 diabetes and healthy controls
Yabe, D., Kuroe, A., Lee, S., Watanabe, K., Hyo, T., Hishizawa, M., Kurose, T., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N. & Seino, Y., Jan 2010, In: Journal of Diabetes Investigation. 1, 1/2, p. 56-59Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of fat supplementation on postprandial GIP, GLP-1, ghrelin and IGFBP-1 levels: a pilot study on adolescents with type 1 diabetes
Lodefalk, M., Carlsson-Skwirut, C., Holst, Jens Juul, Aman, J. & Bang, P., 1 Jan 2010, In: Hormone research in pædiatrics. 73, 5, p. 355-362 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon and glucagon-like peptides 1 and 2
Holst, Jens Juul, 1 Jan 2010, In: Results and Problems in Cell Differentiation. 50, p. 121-35 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of glucagon-like Peptide-2 receptor agonists on colonic anastomotic wound healing
Redstone, H. A., Buie, W. D., Hart, D. A., Wallace, L., Hornby, P. J., Sague, S., Holst, Jens Juul & Sigalet, D. L., 1 Jan 2010, In: Gastroenterology Research and Practice. 2010, p. Article ID 672453 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of glucagon-like peptide-2 on arterial blood flow and cardiac parameters
Bremholm, L., Hornum, Mads, Andersen, U. B. & Holst, Jens Juul, 8 Jan 2010, In: Regulatory Peptides. 159, 1-3, p. 67-71 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: new advances
Asmar, M. & Holst, Jens Juul, 1 Feb 2010, In: Current Opinion in Endocrinology, Diabetes and Obesity. 17, 1, p. 57-62 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular and metabolic effects of 48-h glucagon-like peptide-1 infusion in compensated chronic patients with heart failure
Halbirk, M., Nørrelund, H., Møller, N., Holst, Jens Juul, Schmitz, O., Nielsen, B. R. R., Nielsen-Kudsk, J. E., Nielsen, S. S., Nielsen, T. T., Eiskjaer, H., Bøtker, H. E. & Wiggers, H., 1 Mar 2010, In: American Journal of Physiology: Heart and Circulatory Physiology. 298, 3, p. H1096-H1102Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar incretin secretion in obese and non-obese Japanese subjects with type 2 diabetes
Kozawa, J., Okita, K., Imagawa, A., Iwahashi, H., Holst, Jens Juul, Yamagata, K. & Shimomura, I., 12 Mar 2010, In: Biochemical and Biophysical Research Communications. 393, 3, p. 410-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reversible hyperinsulinemic hypoglycemia after gastric bypass: a consequence of altered nutrient delivery
McLaughlin, T., Peck, M., Holst, Jens Juul & Deacon, Carolyn F., Apr 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 4, p. 1851-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Automated detection of hypoglycemia-induced EEG changes recorded by subcutaneous electrodes in subjects with type 1 diabetes--the brain as a biosensor
Juhl, C. B., Højlund, K., Elsborg, R., Poulsen, M. K., Selmar, P. E., Holst, Jens Juul, Christiansen, C. & Beck-Nielsen, H., 1 Apr 2010, In: Diabetes Research and Clinical Practice. 88, 1, p. 22-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inappropriate glucagon response after oral compared with isoglycemic intravenous glucose administration in patients with type 1 diabetes
Hare, K. J., Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 1 Apr 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 4, p. E832-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of exercise-induced weight loss on appetite-related peptides and motivation to eat
Martins, C., Kulseng, B., King, N. A., Holst, Jens Juul & Blundell, J. E., 1 Apr 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 4, p. 1609-16 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus
Aaboe, K., Knop, Filip Krag, Vilsbøll, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, S. & Krarup, T. M., 1 Apr 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-33 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Little enhancement of meal-induced glucagon-like peptide 1 secretion in Japanese: Comparison of type 2 diabetes patients and healthy controls
Yabe, D., Kuroe, A., Lee, S., Watanabe, K., Hyo, T., Hishizawa, M., Kurose, T., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N. & Seino, Y., 22 Apr 2010, In: Journal of Diabetes Investigation. 1, 1-2, p. 56-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?
Asmar, M., Bache, M., Knop, Filip Krag, Madsbad, Sten & Holst, Jens Juul, 1 May 2010, In: The Journal of clinical endocrinology and metabolism. 95, 5, p. 2367-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of nutrients, biliary-pancreatic secretions, and systemic trophic hormones on intestinal adaptation in a Roux-en-Y bypass model
Taqi, E., Wallace, L. E., de Heuvel, E., Chelikani, P. K., Zheng, H., Berthoud, H., Holst, Jens Juul & Sigalet, D. L., 1 May 2010, In: European Journal of Pediatric Surgery. Supplement. 45, 5, p. 987-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Actions of prolonged ghrelin infusion on gastrointestinal transit and glucose homeostasis in humans
Falkén, Y., Hellström, P. M., Sanger, G. J., Dewit, O., Dukes, G., Grybäck, P., Holst, Jens Juul & Näslund, E., 1 Jun 2010, In: Neurogastroenterology and Motility. 22, 6, p. e192-200Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of growth in infancy on body composition, insulin resistance, and concentration of appetite hormones in adolescence
Larnkjær, Anni, Schack-Nielsen, L., Mølgaard, Christian, Ingstrup, H. K., Holst, Jens Juul & Michaelsen, Kim F., 1 Jun 2010, In: American Journal of Clinical Nutrition. 91, 6, p. 1675-83 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet impairs the incretin effect in healthy subjects
Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 1 Jul 2010, In: The Journal of clinical endocrinology and metabolism. 95, 7, p. 3309-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action
Hare, K. J., Vilsbøll, Tina, Asmar, M., Deacon, Carolyn F., Knop, Filip Krag & Holst, Jens Juul, 1 Jul 2010, In: Diabetes. 59, 7, p. 1765-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase expression during experimental colitis in mice
Yazbeck, R., Sulda, M. L., Howarth, G. S., Bleich, A., Raber, K., von Hörsten, S., Holst, Jens Juul & Abbott, C. A., 1 Aug 2010, In: Inflammatory Bowel Diseases. 16, 8, p. 1340-1351 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of exogenous hyperglucagonemia on postprandial concentrations of gastric inhibitory polypeptide and glucagon-like peptide-1 in humans
Meier, J. J., Ritter, P. R., Jacob, A., Menge, B. A., Deacon, Carolyn F., Schmidt, W. E., Nauck, M. A. & Holst, Jens Juul, 1 Aug 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 8, p. 4061-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex steroids affect triglyceride handling, glucose-dependent insulinotropic polypeptide, and insulin sensitivity: a 1-week randomized clinical trial in healthy young men
Lapauw, B., Ouwens, M., 't Hart, L. M., Wuyts, B., Holst, Jens Juul, T'Sjoen, G., Kaufman, J. & Ruige, J. B., 1 Aug 2010, In: Diabetes Care. 33, 8, p. 1831-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2, but not glucose-dependent insulinotropic polypeptide, stimulates glucagon release in patients with type 1 diabetes
Christensen, M., Knop, Filip Krag, Vilsbøll, Tina, Aaboe, K., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 9 Aug 2010, In: Regulatory Peptides. 163, 1-3, p. 96-101 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans
Asmar, M., Simonsen, L., Madsbad, Sten, Stallknecht, Bente Merete, Holst, Jens Juul & Bülow, J., 1 Sep 2010, In: Diabetes. 59, 9, p. 2160-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of pancreatic enzyme supplementation on postprandial responses of glucagon-like Peptide-2 in patients with chronic pancreatitis and pancreatic exocrine insufficiency
Knop, Filip Krag, Vilsbøll, Tina, Lund, A., Krarup, T., Holst, Jens Juul & Hornum, Mads, 6 Sep 2010, In: Journal of the Pancreas. 11, 5, p. 489-91 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon suppression during OGTT worsens while suppression during IVGTT sustains alongside development of glucose intolerance in patients with chronic pancreatitis
Knop, Filip Krag, Vilsbøll, Tina, Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T. M., 24 Sep 2010, In: Regulatory Peptides. 164, 2-3, p. 144-50 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake
Taylor-Edwards, C. C., Burrin, D. G., Matthews, J. C., McLeod, K. R., Holst, Jens Juul & Harmon, D. L., 1 Oct 2010, In: Domestic Animal Endocrinology. 39, 3, p. 181-93 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin
Rasmussen, A. R., Viby, N., Hare, K. J., Hartmann, Bolette, Thim, L., Holst, Jens Juul & Poulsen, Steen Seier, 1 Oct 2010, In: Digestive Diseases and Sciences. 55, 10, p. 2785-96 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kardiale virkninger af glukagonlignende peptid 1
Holst, Jens Juul, 11 Oct 2010, In: Ugeskrift for Laeger. 172, 41, p. 2821 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A cereal-based evening meal rich in indigestible carbohydrates increases plasma butyrate the next morning
Nilsson, A. C., Östman, E. M., Knudsen, K. E. B., Holst, Jens Juul & Björck, I. M. E., 1 Nov 2010, In: Journal of Nutrition. 140, 11, p. 1932-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis
Edholm, T., Degerblad, M., Grybäck, P., Hilsted, Linda, Holst, Jens Juul, Jacobsson, H., Efendic, S., Schmidt, P. T. & Hellström, P. M., 1 Nov 2010, In: Neurogastroenterology and Motility Online. 22, 11, p. 1191-200, e315 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1
Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, J. J., Deacon, C., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D. & 2 others, , 1 Dec 2010, In: Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained glucagon-like peptide-2 infusion is required for intestinal adaptation, and cessation reverses increased cellularity in rats with intestinal failure
Koopmann, M. C., Chen, X., Holst, Jens Juul & Ney, D. M., 1 Dec 2010, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 299, 6, p. G1222-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of insulin resistance and obesity by stimulating GLP-1 release
Hansen, Harald S., Diep, T. A., Holst, Jens Juul, Rosenkilde, Mette & Andersen, N. W., 29 Dec 2010, IPC No. A61K 31/23, Patent No. PCT/DK2010/050161, 24 Jun 2010Research output: Patent
- 2011
- Published
2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans
Hansen, K. B., Rosenkilde, Mette, Knop, Filip Krag, Wellner, N., Diep, T. A., Rehfeld, Jens Frederik, Andersen, U. B., Holst, Jens Juul & Hansen, Harald S., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A low glycemic index diet does not affect postprandial energy metabolism but decreases postprandial insulinemia and increases fullness ratings in healthy women
Krog-Mikkelsen, I., Sloth, B., Dimitrov, D., Tetens, Inge , Björck, I., Flint, A., Holst, Jens Juul, Astrup, A., Elmstähl, H. & Raben, Anne, 2011, In: Journal of Nutrition. 141, 9, p. 1679-1684 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression
Wang, Q., Bailey, C. G., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M. L., Hendy, S. C., Buchanan, G., Nelson, C. C., Rasko, J. E. J., Holst, J. & Holst, Jens Juul, 2011, In: Cancer Research. 71, 24, p. 7525-7536 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery: Role of Gut Peptides
Falkén, Y., Hellström, P. M., Holst, Jens Juul & Näslund, E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 7, p. 2227-35 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Counter-regulatory hormone responses to spontaneous hypoglycaemia during treatment with insulin Aspart or human soluble insulin: a double-blinded randomized cross-over study
Brock Jacobsen, I., Vind, B. F., Korsholm, L., Flyvbjerg, A., Frystyk, J., Holst, Jens Juul, Beck-Nielsen, H. & Henriksen, J. E., 2011, In: Acta Physiologica (Print). 202, 3, p. 337-347 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delayed ß-cell response and glucose intolerance in young women with Turner syndrome
Hjerrild, B. E., Holst, Jens Juul, Juhl, C., Christiansen, J. S., Schmitz, O. & Gravholt, C. H., 2011, In: B M C Endocrine Disorders. 11, p. 11-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs
Hjøllund, K. R., Deacon, Carolyn F. & Holst, Jens Juul, 2011, In: Diabetologia. 54, 8, p. 2206-8 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Dose response of subcutaneous GLP-1 infusion in patients with type 2 diabetes
Torekov, Signe Sørensen, Kipnes, M. S., Harley, R. E., Holst, Jens Juul & Ehlers, M. R., 2011, In: Diabetes, Obesity and Metabolism. 13, 7, p. 639-43 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes
Henry, R. R., Smith, S., Schwartz, S., Mudaliar, S. R., Deacon, Carolyn F., Holst, Jens Juul, Duan, R. Y., Chen, R. S. & List, J. F., 2011, In: Diabetes, Obesity and Metabolism. 13, 9, p. 850-858 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction
Lønborg, Jacob Thomsen, Vejlstrup, N., Kelbæk, H., Bøtker, H. E., Kim, W. Y., Mathiasen, A. B., Jørgensen, E., Helqvist, S., Saunamäki, K., Clemmensen, P., Holmvang, Lene, Thuesen, L., Krusell, L. R., Jensen, J. S., Køber, Lars Valeur, Treiman, M., Holst, Jens Juul & Engstrøm, Thomas, 2011, In: European Heart Journal. 33, 12, p. 1491-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes
Mentis, N., Vardarli, I., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Theodorakis, M., Meier, J. J. & Nauck, M. A., 2011, In: Diabetes. 60, 4, p. 1270-1276 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric bypass and duodenal and gastric feeding: a comment to Hansen et al
Jorgensen, N. B., Dirksen, C., Holst, Jens Juul & Madsbad, Sten, 2011, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 5, p. G938-G9389 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying of orally administered glucose solutions and incretin hormone responses are unaffected by laparoscopic adjustable gastric banding
Usinger, Lotte, Hansen, K. B., Kristiansen, V. B., Larsen, S., Holst, Jens Juul & Knop, Filip Krag, 2011, In: Obesity Surgery. 21, 5, p. 625-32 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation within the TRPM5 locus associates with prediabetic phenotypes in subjects at increased risk for type 2 diabetes
Ketterer, C., Müssig, K., Heni, M., Dudziak, K., Randrianarisoa, E., Wagner, R., Machicao, F., Stefan, N., Holst, Jens Juul, Fritsche, A., Häring, H. & Staiger, H., 2011, In: Metabolism. 60, 9, p. 1325-1333 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon like-peptide 1 receptor and the liver
Pedersen, Jens & Holst, Jens Juul, 2011, In: Liver international : official journal of the International Association for the Study of the Liver. 31, 9, p. 1243-5 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 (Glp-2) stimulates intestinal function during weaning
Thymann, Thomas, Huërou-Luron, I. L., Petersen, Y. M., Hedemann, M. S., Elnif, J., Jensen, B. B., Hartmann, Bolette, Holst, Jens Juul & Sangild, Per Torp, 2011, 44th annual meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, 2011: programme and abstract booklet. The European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN), p. 202 1 p.Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research
- Published
Glucagon-like peptide-2 (GLP-2) increases small intestinal blood flow and mucosal growth in ruminating calves
Taylor-Edwards, C. C., Burrin, D. G., Holst, Jens Juul, McLeod, K. R. & Harmon, D. L., 2011, In: Journal of Dairy Science. 94, 2, p. 888-898 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans
Christensen, M., Vedtofte, L., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2011, In: Diabetes. 60, 12, p. 3103-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1
Torekov, S. S., Ma, L., Grarup, N., Hartmann, B., Hainerová, I. A., Kielgast, U., Kissow, H., Rosenkilde, M., Lebl, J., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Madsen, O. D., Wang, J., Linneberg, A., Madsbad, S., Holst, J. J., Hansen, T., Pedersen, O. & 1 others, , 2011, In: Diabetologia. 54, 11, p. 2820-31 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired regulation of the incretin effect in patients with type 2 diabetes
Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, drb459, drb459, Holst, Jens Juul & Vilsbøll, Tina, 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 3, p. 737-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Postprandial GIP and Glucagon Responses, But Unaltered GLP-1 Response after Intervention with Steroid Hormone, Relative Physical Inactivity, And High-Calorie Diet in Healthy Subjects
Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 2, p. 447-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased postprandial glycaemia, insulinemia, and lipidemia after 10 weeks’ sucrose-rich diet compared to an artificially sweetened diet: a randomised controlled trial
Raben, Anne, Møller, B. K., Flint, A., Vasilaris, T. H., Møller, A. C., Holst, Jens Juul & Astrup, A., 2011, In: Food & Nutrition Research. 55, 5961, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as "isoglycemic" intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes
Vardarli, I., Nauck, M. A., Köthe, L. D., Deacon, Carolyn F., Holst, Jens Juul, Schweizer, A. & Foley, J. E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 4, p. 945-954 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inkretiner
Vilsbøll, Tina & Holst, Jens Juul, 2011, Diabetes - sygdom, behandling og organisation. Hilsted, J., Borch-Johnsen, K. & Christiansen, J. S. (eds.). 2 ed. København: Munksgaard , p. 67-74 8 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Involvement of endogenous glucagon-like peptide-1 in regulation of gastric motility and pancreatic endocrine secretion
Witte, A., Grybäck, P., Jacobsson, H., Näslund, E., Hellström, P. M., Holst, Jens Juul, Hilsted, Linda & Schmidt, P. T., 2011, In: Scandinavian Journal of Gastroenterology. Supplement. 46, 4, p. 428-35 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide Treatment Is Associated with a Low Frequency and Magnitude of Antibody Formation with No Apparent Impact on Glycemic Response or Increased Frequency of Adverse Events: Results from the Liraglutide Effect and Action in Diabetes (LEAD) trials
Buse, J. B., Garber, A., Rosenstock, J., Schmidt, W. E., Brett, J. H., Videbæk, N., Holst, Jens Juul & Nauck, M., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 6, p. 1695-702 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lixisenatide for type 2 diabetes mellitus
Christensen, M., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2011, In: Expert Opinion on Investigational Drugs. 20, 4, p. 549-57 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test
Møller, J. B., Jusko, W. J., Gao, W., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Overgaard, R. V., Madsen, H. & Ingwersen, S. H., 2011, In: Journal of Pharmacokinetics and Pharmacodynamics. 38, 6, p. 713-25 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuroprotective properties of GLP-1: theoretical and practical applications
Holst, Jens Juul, Burcelin, R. & Nathanson, E., 2011, In: Current Medical Research and Opinion. 27, 3, p. 547-58 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity - an indication for GLP-1 treatment? Obesity pathophysiology and GLP-1 treatment potential
Torekov, Signe Sørensen, Madsbad, Sten & Holst, Jens Juul, 2011, In: Obesity Reviews. 12, 8, p. 593-601 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein dose-response effect on glp-1, pyy and appetite in male subjects
Sparre, A. B., Sørensen, M. Q., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2011, In: Obesity Reviews. 12, suppl. 1, p. 59 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans
Nauck, M. A., Kemmeries, G., Holst, Jens Juul & Meier, J. J., 2011, In: Diabetes. 60, 5, p. 1561-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down?
Nauck, M. A., Vardarli, I., Deacon, Carolyn F., Holst, Jens Juul & Meier, J., 2011, In: Diabetologia. 54, 1, p. 10-18 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients
Bremholm, L., Hornum, Mads, Andersen, U. B., Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2011, In: Regulatory Peptides. 168, 1-3, p. 32-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of dietary fish oil in addition to lifestyle counselling on lipid oxidation and body composition in slightly overweight teenage boys
Pedersen, M. H., Mølgaard, Christian, Hellgren, L., Matthiessen, J., Holst, Jens Juul & Lauritzen, Lotte, 2011, In: Journal of Nutrition and Metabolism. 2011, 348368, 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of L-arabinose on intestinal sucrase activity: dose-response studies in vitro and in humans
Krog-Mikkelsen, I., Hels, O., Tetens, Inge , Holst, Jens Juul, Andersen, Jens Rikardt & Bukhave, K., 2011, In: American Journal of Clinical Nutrition. 94, 2, p. 472-478 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes
Lund, Asger Bach, Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 6, p. E1038-E1046 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Upregulation of alpha cell glucagon-like peptide 1 (GLP-1) in Psammomys obesus--an adaptive response to hyperglycaemia?
Hansen, A. M. K., Bödvarsdottir, T. B., Nordestgaard, D. N. E., Heller, Rasmus, Gotfredsen, C. F., Maedler, K., Fels, J., Holst, Jens Juul & Karlsen, A., 2011, In: Diabetologia. 54, 6, p. 1379-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Women with bulimia nervosa exhibit attenuated secretion of glucagon-like peptide 1, pancreatic polypeptide, and insulin in response to a meal
Naessén, S., Carlström, K., Holst, Jens Juul, Hellström, P. M. & Hirschberg, A. L., 2011, In: American Journal of Clinical Nutrition. 94, 4, p. 967-972 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test
Gjesing, A. P., Kjems, L. L., Vestmar, M. A., Grarup, Niels, Linneberg, Allan René, Deacon, Carolyn F., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: Diabetologia. 54, 1, p. 103-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of PCSK1 Variants on Waist, Waist-Hip Ratio and Glucose Metabolism Is Modified by Sex and Glucose Tolerance Status
Gjesing, A. P., Vestmar, M. A., Jørgensen, T., Heni, M., Holst, Jens Juul, Witte, D. R., Hansen, Torben & Pedersen, Oluf Borbye, 1 Jan 2011, In: P L o S One. 6, 9, p. e23907 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma levels of glucagon like peptide-1 associate with diastolic function in elderly men
Nathanson, D., Zethelius, B., Berne, C., Lind, L., Andrén, B., Ingelsson, E., Holst, Jens Juul & Nyström, T., Mar 2011, In: Diabetic Medicine. 28, 3, p. 301-305 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-6 has no acute effect on the regulation of urea synthesis in vivo in rats
Thomsen, K., Aagaard, N. K., Grønbæk, H., Holst, Jens Juul, Jessen, N., Frystyk, J. & Vilstrup, H., Apr 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 2, p. 150-156 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition de la sécrétion du glucagon par les antagonistes du GLP-1 et les inhibiteurs de la DPP-4
Hansen, M., Knop, Filip Krag & Holst, Jens Juul, Apr 2011, In: Medecine des Maladies Metaboliques. 5, 2Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future
Madsbad, Sten, Kielgast, U., Asmar, M., Deacon, Carolyn F., Torekov, Signe Sørensen & Holst, Jens Juul, May 2011, In: Diabetes, Obesity and Metabolism. 13, 5, p. 394-407 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual ß-cell function
Kielgast, U., Holst, Jens Juul & Madsbad, Sten, May 2011, In: Diabetes. 60, 5, p. 1599-1607 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes
Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, May 2011, In: Diabetes Care. 34, Supplement 2, p. S251-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of glucagon secretion by GLP-1 agonists and DPP4 inhibitors
Hansen, M., Juul Hare, K., Holst, Jens Juul & Knop, Filip Krag, Jun 2011, In: Journal of Clinical Metabolism & Diabetes. 2, 2, p. 7-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KU bestemmer selv over sin forskning
Wewer, Ulla M., Holst, Jens Juul, Schwartz, Thue W. & Quistorff, B., 2 Jun 2011, In: Universitetsavisen.Research output: Contribution to journal › Contribution to newspaper - Comment/debate › Communication
- Published
Dissociated incretin hormone response to protein versus fat ingestion in obese subjects
Lindgren, O., Carr, R., Holst, Jens Juul, Deacon, Carolyn F. & Ahren, B., Jul 2011, In: Diabetes, Obesity and Metabolism Online. 13, 9, p. 863-865 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function
Kielgast, U., Krarup, T., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jul 2011, In: Diabetes Care. 34, 7, p. 1463-1468 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glutamine reduces postprandial glycemia and augments the glucagon-like peptide-1 response in type 2 diabetes patients
Samocha-Bonet, D., Wong, O., Synnott, E., Piyaratna, N., Douglas, A., Gribble, F. M., Holst, Jens Juul, Chisholm, D. J. & Greenfield, J. R., Jul 2011, In: Journal of Nutrition. 141, 7, p. 1233-1238 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Administration of a dipeptidyl peptidase IV inhibitor enhances the intestinal adaptation in a mouse model of short bowel syndrome
Okawada, M., Holst, Jens Juul & Teitelbaum, D. H., Aug 2011, In: Surgery. 150, 2, p. 217-223 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormone and insulin responses to oral versus intravenous lipid administration in humans
Lindgren, O., Carr, R. D., Deacon, Carolyn F., Holst, Jens Juul, Pacini, G., Mari, A. & Ahrén, B., Aug 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 8, p. 2519-2524 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type 2 diabetes
Menge, B. A., Grüber, L., Jørgensen, S. M., Deacon, Carolyn F., Schmidt, W. E., Veldhuis, J. D., Holst, Jens Juul & Meier, J. J., Aug 2011, In: Diabetes. 60, 8, p. 2160-2168 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiological and pharmacological mechanisms through which the DPP-4 inhibitor sitagliptin regulates glycemia in mice
Waget, A., Cabou, C., Masseboeuf, M., Cattan, P., Armanet, M., Karaca, M., Castel, J., Garret, C., Payros, G., Maida, A., Sulpice, T., Holst, Jens Juul, Drucker, D. J., Magnan, C. & Burcelin, R., Aug 2011, In: Endocrinology. 152, 8, p. 3018-3029 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying, glucose metabolism and gut hormones: evaluation of a common preoperative carbohydrate beverage
Vermeulen, M. A. R., Richir, M. C., Garretsen, M. K., van Schie, A., Ghatei, M. A., Holst, Jens Juul, Heijboer, A. C., Uitdehaag, B. M. J., Diamant, M., Eekhoff, E. M. W., van Leeuwen, P. A. M. & Ligthart-Melis, G. C., Sep 2011, In: Nutrition. 27, 9, p. 897-903 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial insulin secretion after gastric bypass surgery: the role of glucagon-like peptide 1
Holst, Jens Juul, Sep 2011, In: Diabetes. 60, 9, p. 2203-2205 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Foetal proglucagon processing in relation to adult appetite control: lessons from a transplantable rat glucagonoma with severe anorexia
Jensen, P. B., Larsen, P. J., Karlsen, C., Jensen, H. I., Holst, Jens Juul & Madsen, O. D., Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl. 1, p. 60-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of glucagon secretion by incretins
Holst, Jens Juul, Christensen, M., Lund, A., de Heer, J., Svendsen, B., Kielgast, U. & Knop, Filip Krag, Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl 1, p. 89-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Could the mechanisms of bariatric surgery hold the key for novel therapies? report from a Pennington Scientific Symposium
Tam, C. S., Berthoud, H., Bueter, M., Chakravarthy, M. V., Geliebter, A., Hajnal, A., Holst, Jens Juul, Kaplan, L., Pories, W., Raybould, H., Seeley, R., Strader, A. & Ravussin, E., Nov 2011, In: Obesity Reviews. 12, 11, p. 984-94 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of method of delivery of sodium butyrate on rumen development in newborn calves
Górka, P., Kowalski, Z. M., Pietrzak, P., Kotunia, A., Jagusiak, W., Holst, Jens Juul, Guilloteau, P. & Zabielski, R., Nov 2011, In: Journal of Dairy Science. 94, 11, p. 5578-88 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus
Stephens, J. W., Bodvarsdottir, T. B., Wareham, K., Prior, S. L., Bracken, R. M., Lowe, G. D., Rumley, A., Dunseath, G., Luzio, S., Deacon, Carolyn F., Holst, Jens Juul & Bain, S. C., Nov 2011, In: Diabetes Research and Clinical Practice. 94, 2, p. 199-206 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon antagonism as a potential therapeutic target in type 2 diabetes
Bagger, J. I., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, Nov 2011, In: Diabetes, Obesity and Metabolism. 13, 11, p. 965-971 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain
Ugleholdt, Randi Kjærsgaard, Pedersen, Jens, Bassi, Maria Rosaria, Füchtbauer, E., Jørgensen, S. M., Kissow, Hannelouise, Nytofte, N., Poulsen, Steen Seier, Rosenkilde, Mette, Seino, Y., Thams, P., Holst, Peter Johannes & Holst, Jens Juul, Dec 2011, In: The Journal of Biological Chemistry. 286, 52, p. 44632-44645 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance
Jørgensen, N. B., Jacobsen, S. H., Dirksen, C., Bojsen-Møller, K. N., Naver, L., Hvolris, L., Clausen, T. R., Wulff, B. S., Worm, Dorte, Lindqvist Hansen, D., Madsbad, Sten & Holst, Jens Juul, 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 303, 1, p. E122-31Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute differential effects of milk-derived dietary proteins on postprandial lipaemia in obese non-diabetic subjects
Holmer-Jensen, J., Hartvigsen, M., Mortensen, L. S., Astrup, A., de Vrese, M., Holst, Jens Juul, Thomsen, C. & Hermansen, K., 2012, In: European Journal of Clinical Nutrition. 66, p. 32-38 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alcohol intake and its effect on some appetite-regulating hormones in man: influence of gastroprotection with sucralfate
Calissendorff, J., Gustafsson, T., Holst, Jens Juul, Brismar, K. & Röjdmark, S., 2012, In: Endocrine Research. 37, 3, p. 154-62 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in Gastrointestinal Hormone Responses, Insulin Sensitivity, and Beta-Cell Function Within 2 Weeks After Gastric Bypass in Non-diabetic Subjects
Jacobsen, S. H., Olesen, S. C., Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Worm, Dorte, Almdal, Thomas Peter, Naver, L. S., Hvolris, L. E., Rehfeld, Jens Frederik, Wulff, B. S., Clausen, T. R., Hansen, D. L., Holst, Jens Juul & Madsbad, Sten, 2012, In: Obesity Surgery. 22, 7, p. 1084-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of different fractions of whey protein on postprandial lipid and hormone responses in type 2 diabetes
Mortensen, L. S., Holmer-Jensen, J., Hartvigsen, M., Jensen, V. K., Astrup, A., Vrese, M. D., Holst, Jens Juul, Thomsen, C. H. P. & Hermansen, K., 2012, In: European Journal of Clinical Nutrition. 66, 7, p. 799-805 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of everyday life events on glucose, insulin, and glucagon dynamics in continuous subcutaneous insulin infusion-treated type 1 diabetes: collection of clinical data for glucose modeling
Schmidt, S. D., Finan, D. A., Duun-Henriksen, A. K., Jørgensen, J. B., Madsen, H., Bengtsson, H., Holst, Jens Juul, Madsbad, S. & Nørgaard, K., 2012, In: Diabetes Technology & Therapeutics. 14, 3, p. 210-217 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of pre-meal drinks with protein and amino acids on glycemic and metabolic responses at a subsequent composite meal
Gunnerud, U. J., Heinzle, C., Holst, Jens Juul, Östman, E. M. & Björck, I. M. E., 2012, In: P L o S One. 7, 9, p. e44731Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs
Jain, A. K., Stoll, B., Burrin, D. G., Holst, Jens Juul & Moore, D. D., 2012, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 302, 2, p. G218-24Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine
Kissow, Hannelouise, Viby, N., Hartmann, Bolette, Holst, Jens Juul, Timm, M., Thim, L. & Poulsen, Steen Seier, 2012, In: Cancer Chemotherapy and Pharmacology. Supplement. 70, 1, p. 39-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits
Gjesing, A. M. P., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Urhammer, S. A., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Teis Schjals, 2012, In: Diabetologia. 55, 5, p. 1338-1345 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of postprandial glycaemia on health and prevention of disease
Blaak, E. E., Antoine, J., Benton, D., Björck, I., Bozzetto, L., Brouns, F., Diamant, M., Dye, L., Hulshof, T., Holst, Jens Juul, Lamport, D. J., Laville, M., Lawton, C. L., Meheust, A., Nilson, A., Normand, S., Rivellese, A. A., Theis, S., Torekov, Signe Sørensen & Vinoy, S., 2012, In: Obesity Reviews. 13, 10, p. 923-984Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired crosstalk between pulsatile insulin and glucagon secretion in prediabetic individuals
Rohrer, S., Menge, B. A., Grüber, L., Deacon, Carolyn F., Schmidt, W. E., Veldhuis, J. D., Holst, Jens Juul & Meier, J. J., 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 5, p. E791-E795Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity
Knop, Filip Krag, Aaboe, K., Vilsbøll, Tina, Vølund, A., Holst, Jens Juul, Krarup, T. & Madsbad, Sten, 2012, In: Diabetes, Obesity and Metabolism. 14, 6, p. 500-510 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired incretin-induced amplification of insulin secretion after glucose homeostatic dysregulation in healthy subjects
Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 4, p. 1363-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele
Faerch, K., Pilgaard, K., Knop, Filip Krag, Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T. & Holst, Jens Juul, 2012, In: Diabetes, Obesity and Metabolism Online. 15, 1, p. 91-95 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin based therapies: do they hold their promise?
Holst, Jens Juul, 2012, In: Journal of Diabetes. 4, 1, p. 4-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leptin og dens betydning for vægtvedligeholdelse
Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2012, In: Klinisk biokemi i Norden. 24, 4, p. 8-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Linagliptin, a selective DPP-4 inhibitor, inhibits DPP-4, increases incretin levels, lowers glucagon, and improves glycaemic control in patients with Type 2 diabetes.
Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. & Heise, T., 2012, In: Diabetes Therapy. 3, 1, p. 10Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass
Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Jacobsen, S. H., Hansen, D. L., Worm, Dorte, Holst, Jens Juul & Madsbad, Sten, 2012, In: Diabetologia. 55, 7, p. 1890-901 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic effects of short-term GLP-1 treatment in insulin resistant heart failure patients
Nielsen, R., Wiggers, H., Halbirk, M., Bøtker, H., Holst, Jens Juul, Schmitz, O., Frandsen, E. R., Nielsen, S., Møller, N. & Nørrelund, H., 2012, In: Experimental and Clinical Endocrinology and Diabetes. 120, 5, p. 266-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus: focus on bile acid sequestrants
Holst, Jens Juul & McGill, M. A., 2012, In: Clinical Drug Investigation. 32, 1, p. 1-14 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged successful therapy for hyperinsulinaemic hypoglycaemia after gastric bypass: the pathophysiological role of GLP1 and its response to a somatostatin analogue
Myint, K. S., Greenfield, J. R., Farooqi, I. S., Henning, E., Holst, Jens Juul & Finer, N., 2012, In: European Journal of Endocrinology. 166, 5, p. 951-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Randomised controlled trial of colostrum to improve intestinal function in patients with short bowel syndrome
Lund, P., Sangild, Per Torp, Aunsholt, L., Hartmann, Bolette, Holst, Jens Juul, Mortensen, J., Mortensen, P. B. & Jeppesen, P. B., 2012, In: European Journal of Clinical Nutrition. 66, 9, p. 1059-1065 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects: a possible link between obesity and local tissue inflammation?
Arngrim, N., Simonsen, L., Holst, Jens Juul & Bülow, J., 2012, In: International Journal of Obesity. 37, p. 748-50Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roux-en-Y gastric bypass surgery does not preserve energy expenditure in humans
Schmidt, J. B., Gunvald, L. E., Gregersen, N. T., Pedersen, S. D., Holst, Jens Juul, Hansen, D. L., Worm, Dorte, Madsbad, Sten, Astrup, A. & Sjödin, Anders Mikael, 2012, In: Regulatory Peptides. 177, suppl.1, p. S32 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Satiety scores and satiety hormone response after sucrose-sweetened soft drink compared with isocaloric semi-skimmed milk and with non-caloric soft drink: a controlled trial
Nielsen, M. M., Sparre, A. B., Holst, Jens Juul, Fenger-Grøn, M., Pedersen, S. B., Astrup, A. & Richelsen, B., 2012, In: European Journal of Clinical Nutrition. 66, 4, p. 523-529 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes
Jensen, D. H., Aaboe, K., Henriksen, J. E., Vølund, A., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2012, In: Diabetologia. 55, 5, p. 1406-16 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural and functional development of small intestine in intrauterine growth retarded porcine offspring born to gilts fed diets with differing protein ratios throughout pregnancy
Mickiewicz, M., Zabielski, R., Grenier, B., Le Normand, L., Savary, G., Holst, Jens Juul, Oswald, I. P., Metges, C. C. & Guilloteau, P., 2012, In: Journal of Physiology and Pharmacology. 63, 3, p. 225-39 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The combination of colesevelam with sitagliptin enhances glycemic control in diabetic ZDF rat model
Shang, Q., Liu, M. K., Saumoy, M., Holst, Jens Juul, Salen, G. & Xu, G., 2012, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 302, 8, p. G815-23Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glycemic, insulinemic and plasma amino acid responses to equi-carbohydrate milk meals, a pilot- study of bovine and human milk
Gunnerud, U., Holst, Jens Juul, Östman, E. & Björck, I., 2012, In: Nutrition Journal. 11, p. 83Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin effect in patients with maturity onset diabetes of the young
Ostoft, S. H., Bagger, J. I., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2012, In: Diabetologia. 55, p. S144-S144Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The insulinogenic effect of whey protein is partially mediated by a direct effect of amino acids and GIP on β-cells
Salehi, A., Gunnerud, U., Muhammed, S. J., Ostman, E., Holst, Jens Juul, Björck, I. & Rorsman, P., 2012, In: Nutrition & Metabolism. 9, 1, p. 48Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of adult short bowel syndrome patients with teduglutide
Nørholk, L. M., Holst, Jens Juul & Jeppesen, Palle Bekker, 2012, In: Expert Opinion on Pharmacotherapy. 13, 2, p. 235-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of glucagon-like peptide 1 on cardiovascular risk
Sivertsen, J., Rosenmeier, J., Holst, Jens Juul & Vilsbøll, T., Apr 2012, In: Nature Reviews Cardiology. 9, 4, p. 209-22 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPR119 as a fat sensor
Hansen, Harald S., Rosenkilde, Mette, Holst, Jens Juul & Schwartz, Thue W., Jul 2012, In: Trends in Pharmacological Sciences. 33, 7, p. 374-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms for the antihyperglycemic effect of sitagliptin in patients with type 2 diabetes
Muscelli, E., Casolaro, A., Gastaldelli, A., Mari, A., Seghieri, G., Astiarraga, B., Chen, Y., Alba, M., Holst, Jens Juul & Ferrannini, E., Aug 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 8, p. 2818-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of intravenous infusions of PYY3-36 and GLP-1, as monoinfusion and in combination, on ad libitum energy intake in healthy obese subjects
Schmidt, J. B., Gregersen, N. T., Pedersen, S. D., Holst, Jens Juul, Schwartz, Thue W., Astrup, A. & Sjödin, Anders Mikael, 10 Aug 2012, In: Regulatory Peptides. 177, Supplement, p. S32 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs
Stoll, B., Puiman, P. J., Cui, L., Chang, X., Benight, N. M., Bauchart-Thevret, C., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Sep 2012, In: Journal of Parenteral and Enteral Nutrition. 36, 5, p. 538-50 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model
Barnes, J. L., Hartmann, Bolette, Holst, Jens Juul & Tappenden, K. A., Sep 2012, In: Journal of Parenteral and Enteral Nutrition. 36, 5, p. 524-37 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of a very low calorie diet on insulin sensitivity, beta cell function, insulin clearance, incretin hormone secretion, androgen levels and body composition in obese young women
Svendsen, P. F., Jensen, F. K., Holst, Jens Juul, Haugaard, Steen Bendix, Nilas, L. & Madsbad, Sten, Sep 2012, In: Scandinavian Journal of Clinical & Laboratory Investigation. 72, 5, p. 410-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteral nutrients potentiate glucagon-like peptide-2 action and reduce dependence on parenteral nutrition in a rat model of human intestinal failure
Brinkman, A. S., Murali, S. G., Hitt, S., Solverson, P. M., Holst, Jens Juul & Ney, D. M., 1 Sep 2012, In: A J P: Gastrointestinal and Liver Physiology (Online). 303, 5, p. G610-22Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of beta cell and incretin function in patients with MODY1 (HNF4A MODY) and MODY3 (HNF1A MODY) in a Swedish patient collection
Ekholm, E., Shaat, N. & Holst, Jens Juul, Oct 2012, In: Acta Diabetologica. 49, 5, p. 349-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol
Mandoe, M. J., Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Hansen, Harald S., Oct 2012, In: Diabetologia. 55, p. S340-S340Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Molecular mechanisms of lipoapoptosis and metformin protection in GLP-1 secreting cells
Kappe, C., Holst, Jens Juul, Zhang, Q. & Sjöholm, A., 12 Oct 2012, In: Biochemical and Biophysical Research Communications. 427, 1, p. 91-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationships among tonic and episodic aspects of motivation to eat, gut peptides, and weight before and after bariatric surgery
Bryant, E. J., King, N. A., Falkén, Y., Hellström, P. M., Holst, Jens Juul, Blundell, J. E. & Näslund, E., 12 Oct 2012, In: Surgery for Obesity and Related Diseases.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Linagliptin increases incretin levels, lowers glucagon, and improves glycemic control in type 2 diabetes mellitus
Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. A. & Heise, T., Nov 2012, In: Diabetes Therapy. 3, 1, p. 10Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice
Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul, Viby, N., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hare, K. J. & Poulsen, Steen Seier, 10 Nov 2012, In: Regulatory Peptides. 179, 1-3, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adult glucose metabolism in extremely birthweight-discordant monozygotic twins
Frost, M., Petersen, I., Brixen, K., Beck-Nielsen, H., Holst, Jens Juul, Christiansen, L., Højlund, K. & Christensen, K., Dec 2012, In: Diabetologia. 55, 12, p. 3204-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chenodeoxycholic acid reduces intestinal permeability in newly weaned piglets
van der Meer, Y., Gerrits, W. J. J., van den Bosch, M., Holst, Jens Juul, Moreto, M., Buurman, W. A., Kulik, W. & van Kempen, T. A. T. G., Dec 2012, In: Journal of Animal Science. 90 Suppl 4, p. 302-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Examining the effects of hyperglycemia on pancreatic endocrine function in humans: evidence for in vivo glucotoxicity
Solomon, T. P. J., Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul & Pedersen, Bente Klarlund, Dec 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 12, p. 4682-91 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 decreases intracerebral glucose content by activating hexokinase and changing glucose clearance during hyperglycemia
Gejl, M., Egefjord, L., Lerche, S., Vang, K., Bibby, B. M., Holst, Jens Juul, Mengel, A., Møller, N., Rungby, J., Brock, B. & Gjedde, Albert, Dec 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, 12, p. 2146-2152 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 (GLP-2) increases net amino acid utilization by the portal-drained viscera of ruminating calves
Taylor-Edwards, C. C., Burrin, D. G., Kristensen, N. B., Holst, Jens Juul, McLeod, K. R. & Harmon, D. L., Dec 2012, In: Animal. 6, 12, p. 1985-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)
Verbrugghe, A., Hesta, M., Daminet, S., Polis, I., Holst, Jens Juul, Buyse, J., Wuyts, B. & Janssens, G. P. J., Dec 2012, In: Journal of Animal Physiology and Animal Nutrition (Online). 96, 6, p. 1054-64 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin
Egerod, Kristoffer Lihme, Engelstoft, M. S., Grunddal, Kaare Villum, Nøhr, M. K., Secher, A., Sakata, I., Pedersen, Jens, Windeløv, Johanne Agerlin, Füchtbauer, E., Olsen, Jørgen, Sundler, F., Christensen, Jan Pravsgaard, Wierup, N., Olsen, Jesper Velgaard, Holst, Jens Juul, Zigman, J. M., Poulsen, Steen Seier & Schwartz, Thue W., 1 Dec 2012, In: Endocrinology. 153, 12, p. 5782-95 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
A single supplement of a standardised bilberry (Vaccinium myrtillus L.) extract (36 % wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes controlled by diet and lifestyle
Hoggard, N., Cruickshank, M., Moar, K., Bestwick, C., Holst, Jens Juul, Russell, W. & Horgan, G., 2013, In: Journal of Nutritional Science. 2, 9 p., e22.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects
Holmer-Jensen, J., Mortensen, L. S., Astrup, A., de Vrese, M., Holst, Jens Juul, Thomsen, C. & Hermansen, K., 2013, In: Nutrition Research. 33, 1, p. 34-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combining GLP-1 receptor agonists with insulin: therapeutic rationales and clinical findings
Holst, Jens Juul & Vilsbøll, Tina, 2013, In: Diabetes, Obesity and Metabolism. 15, 1, p. 3-14 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contribution of gastroenteropancreatic appetite hormones to protein-induced satiety
Sparre, A. B., Ritz, C., Sørensen, M. Q., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2013, In: American Journal of Clinical Nutrition. 97, 5, p. 980-989 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
Pedersen, L. R., Olsen, R. H., Frederiksen, M., Astrup, A., Chabanova, E., Hasbak, P., Holst, Jens Juul, Kjær, Andreas, Newman, J. W., Walzem, R., Wisløff, U., Sajadieh, Ahmad, Haugaard, Steen Bendix & Prescott, Eva, 2013, In: B M C Cardiovascular Disorders. 13, 1, 8 p., 106.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a meal rich in medium-chain saturated fat on postprandial lipemia in relatives of type 2 diabetics
Pietraszek, A., Hermansen, K., Pedersen, S. B., Langdahl, B. L., Holst, Jens Juul & Gregersen, S., 2013, In: Nutrition. 29, 7-8, p. 1000-1006 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of oleic acid and olive oil on gastric emptying, gut hormone secretion and appetite in lean and overweight or obese males
Damgaard, Morten, Graff, J., Fuglsang, S., Holst, Jens Juul, Rehfeld, Jens Frederik & Madsen, J. L., 2013, In: e - S P E N Journal. 8, 1, p. e8-e14 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exaggerated release and preserved insulinotropic action of glucagon-like peptide-1 underlie insulin hypersecretion in glucose-tolerant individuals after Roux-en-Y gastric bypass
Dirksen, C., Bojsen-Møller, K. N., Jørgensen, N. B., Jacobsen, S. H., Kristiansen, V. B., Naver, L. S., Hansen, D. L., Worm, Dorte, Holst, Jens Juul & Madsbad, Sten, 2013, In: Diabetologia. 56, 12, p. 2679-2687Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 (GLP-1) raises blood-brain glucose transfer capacity and hexokinase activity in human brain
Gejl, M., Lerche, S., Egefjord, L., Brock, Birgitte, Møller, N., Vang, K., Rodell, A., Bibby, B. M., Holst, Jens Juul, Rungby, J. & Gjedde, Albert, 2013, In: Frontiers in Neuroenergetics. 5, p. 1-9 10 p., 2.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates
Vegge, A., Thymann, Thomas, Lund, P., Stoll, B., Bering, S. B., Hartmann, Bolette, Jelsing, J., Qvist, N., Burrin, D. G., Jeppesen, Palle Bekker, Holst, Jens Juul & Sangild, Per Torp, 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, 4, p. G277-G285 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin
Holst, Jens Juul, Deacon, Carolyn F., Hartmann, Bolette & Pedersen, Jens, 2013, Handbook of Biologically Active Peptides . Kastin, AJ. (ed.). 2 ed. Elsevier, p. 1241-1250 10 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
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Glucose-dependent insulinotropic polypeptide has impaired effect on abdominal, subcutaneous adipose tissue metabolism in obese subjects
Asmar, M., Simonsen, L., Arngrim, N., Holst, Jens Juul, Dela, Flemming & Bülow, J., 2013, In: International journal of obesity (2005). 38, 2, p. 259-65 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Islet-cell dysfunction induced by glucocorticoid treatment: potential role for altered sympathovagal balance?
van Raalte, D. H., Kwa, K. A. A., van Genugten, R. E., Tushuizen, M. E., Holst, Jens Juul, Deacon, Carolyn F., Karemaker, J. M., Heine, R. J., Mari, A. & Diamant, M., 2013, In: Metabolism. 62, 4, p. 568-577 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanisms of the incretin effect in subjects with normal glucose tolerance and patients with type 2 diabetes
Mari, A., Bagger, J. I., Ferrannini, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2013, In: PLOS ONE. 8, 9, p. e73154Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved postprandial GLP-1 and GIP responses in patients with maturity onset diabetes of the young
Bagger, J. I., Ostoft, S. H., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2013, In: Diabetologia. 56, p. S152-S152Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The L-alpha-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in L-arginine-induced insulin release
Smajilovic, S., Clemmensen, Christoffer, Johansen, L. D., Wellendorph, Petrine, Holst, Jens Juul, Thams, P. G., Ogo, E. & Bräuner, Hans, 2013, In: Amino Acids. 44, 2, p. 383-390 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of Roux-en-Y gastric bypass surgery on energy expenditure and appetite: a randomized human study including “pair fed” control subjects
Schmidt, J. B., Gregersen, N. T., Pedersen, S., Nielsen, M. S., Nielsen, L. V., Holst, Jens Juul, Hansen, D. L., Dorm, D. W., Madsbad, Sten, Clausen, T. R. C., Ritz, C., Astrup, A. & Sjödin, Anders Mikael, 2013, In: Obesity Facts. 6, suppl. 1, p. 28 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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The effect of a glucagon-like peptide-1 receptor agonist on glucose tolerance in women with previous gestational diabetes mellitus: protocol for an investigator-initiated, randomised, placebo-controlled, double-blinded, parallel intervention trial
Foghsgaard, S., Vedtofte, L., Mathiesen, Elisabeth, Svare, J. A., Gluud, Lise Lotte, Holst, Jens Juul, Damm, Peter, Knop, Filip Krag & Vilsbøll, T., 2013, In: B M J Open. 3, 10, p. 1-8 9 p., e003834.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells
Pedersen, J., Ugleholdt, Randi Kjærsgaard, Jørgensen, S. M., Windeløv, Johanne Agerlin, Grunddal, Kaare Villum, Schwartz, Thue W., Füchtbauer, E., Poulsen, Steen Seier, Holst, Peter Johannes & Holst, Jens Juul, 1 Jan 2013, In: American Journal of Physiology: Endocrinology and Metabolism. 304, 1, p. E60-73 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 Delays But Does Not Prevent the Onset of Necrotizing Enterocolitis in Preterm Pigs
Benight, N. M., Stoll, B., Olutoye, O. O., Holst, Jens Juul & Burrin, D. G., 21 Jan 2013, In: Journal of Pediatric Gastroenterology and Nutrition. 56, 6, p. 623-30 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased expression of glucagon-like peptide-1 receptors in psoriasis plaques
Faurschou, A., Pedersen, Jens, Gyldenløve, M., Poulsen, Steen Seier, Holst, Jens Juul, Thyssen, Jacob Pontoppidan, Zachariae, Claus, Vilsbøll, Tina, Skov, Lone & Knop, Filip Krag, Feb 2013, In: Experimental Dermatology. 22, 2, p. 150-2 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Removal of Duodenum Elicits GLP-1 Secretion
Muscogiuri, G., Mezza, T., Prioletta, A., Sorice, G. P., Clemente, G., Sarno, G., Nuzzo, G., Pontecorvi, A., Holst, Jens Juul & Giaccari, A., 7 Feb 2013, In: Diabetes Care. 36, 6, p. 1641-1646 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of glucagon-like peptide-2 exposure on bone resorption: Effectiveness of high concentration versus prolonged exposure
Askov-Hansen, C., Jeppesen, Palle Bekker, Lund, P., Hartmann, Bolette, Holst, Jens Juul & Henriksen, D. B., 10 Feb 2013, In: Regulatory Peptides. 181, p. 4-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The C-terminal extension of exendin-4 provides additional metabolic stability when added to GLP-1, while there is minimal effect of truncating exendin-4 in anaesthetized pigs
Simonsen, L., Holst, Jens Juul, Madsen, K. & Deacon, Carolyn F., 10 Feb 2013, In: Regulatory Peptides. 181, 10, p. 17-21 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is there a place for incretin therapies in obesity and prediabetes?
Holst, Jens Juul & Deacon, Carolyn F., 13 Feb 2013, In: Trends in Endocrinology and Metabolism. 24, 3, p. 145-152 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced postprandial GLP-1 responses in women with gestational diabetes mellitus
Bonde, L., Vilsbøll, Tina, Nielsen, T., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Larsen, S. & Knop, Filip Krag, 13 Feb 2013, In: Diabetes, Obesity and Metabolism. 15, 8, p. 713-720 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial gut hormone responses and glucose metabolism in cholecystectomized patients
Sonne, D. P., Hare, K. J., Martens, P., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 15 Feb 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 4, p. G413-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass
Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Jacobsen, S. H., Clausen, T. R., Worm, Dorte, Hartmann, Bolette, Rehfeld, Jens Frederik, Damgaard, Morten, Madsen, J. L., Madsbad, Sten, Holst, Jens Juul & Hansen, D. L., 19 Feb 2013, In: International Journal of Obesity. 37, p. 1452-1459 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells
Kappe, C., Patrone, C., Holst, Jens Juul, Zhang, Q. & Sjöholm, A., Mar 2013, In: Journal of Gastroenterology. 48, 3, p. 322-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fast pouch emptying, delayed small intestinal transit, and exaggerated gut hormone responses after Roux-en-Y gastric bypass
Dirksen, C., Damgaard, Morten, Bojsen-Møller, K. N., Jørgensen, N. B., Kielgast, U., Jacobsen, S. H., Naver, L. S., Worm, Dorte, Holst, Jens Juul, Madsbad, Sten, Hansen, D. L. & Madsen, J. L., Apr 2013, In: Neurogastroenterology and Motility. 25, 4, p. 346-e255 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1): effect on kidney hemodynamics and renin-angiotensin-aldosterone system in healthy men
Skov, J., Dejgaard, A., Frøkiær, J., Holst, Jens Juul, Jonassen, Thomas, Rittig, S. & Christiansen, J. S., Apr 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 4, p. E664-71 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of urea synthesis during the acute-phase response in rats
Thomsen, K. L., Jessen, N., Møller, A. B., Aagaard, N. K., Grønbæk, H., Holst, Jens Juul & Vilstrup, H., 1 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 7, p. G680-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of erythropoietin on cognitive performance during experimental hypoglycemia in patients with type 1 diabetes mellitus: A Randomized Cross-Over Trial
Kristensen, Peter Lommer, Pedersen-Bjergaard, Ulrik, Kjær, T. W., Olsen, N. V., Dela, Flemming, Holst, Jens Juul, Faber, Jens, Tarnow, L. & Thorsteinsson, B., 5 Apr 2013, In: P L o S One. 8, 4, p. 1-8 8 p., e59672.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendahl, C., Vilsbøll, Tina, Knop, Filip Krag & Holst, Jens Juul, 18 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, p. G1117-G1127 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early growth and postprandial appetite regulatory hormone responses
Perälä, M., Kajantie, E., Valsta, L. M., Holst, Jens Juul, Leiviskä, J. & Eriksson, J. G., 19 Apr 2013, In: British Journal of Nutrition. 110, 09, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Hepatic Insulin Clearance After Roux-en-Y Gastric Bypass
Bojsen-Møller, K. N., Dirksen, C., Jørgensen, N. B., Jacobsen, S. H., Hansen, D. L., Worm, Dorte, Naver, L., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 22 Apr 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 6, p. E1066-E1071 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded, parallel intervention study
Idorn, T., Knop, Filip Krag, Jørgensen, M., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 26 Apr 2013, In: B M J Open. 3, 4, p. 1-10 11 p., e002764.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastrointestinal factors contribute to glucometabolic disturbances in nondiabetic patients with end-stage renal disease
Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, May 2013, In: Kidney International. 83, 5, p. 915-23 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of glucagon-like peptide-1 in patients with type 2 diabetes mellitus: systematic review and meta-analyses of clinical studies
Calanna, S., Christensen, M., Holst, Jens Juul, Laferrère, B., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, May 2013, In: Diabetologia. 56, 5, p. 965-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The exaggerated glucagon-like peptide-1 response is important for the improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes
Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Jacobsen, S. H., Worm, Dorte, Hansen, D. L., Kristiansen, V. B., Naver, L., Madsbad, Sten & Holst, Jens Juul, 6 May 2013, In: Diabetes. 62, 9, p. 3044-3052 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thirty days of resveratrol supplementation does not affect postprandial incretin hormone responses, but suppresses postprandial glucagon in obese subjects
Knop, Filip Krag, Konings, E., Timmers, S., Schrauwen, P., Holst, Jens Juul & Blaak, E. E., 11 May 2013, In: Diabetic Medicine. 30, 10, p. 1214-1218 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway
't Hart, L. M., Fritsche, A., Nijpels, G., van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N. A., van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M. C., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., Machicao, F. & 14 others, , 14 May 2013, In: Diabetes. 62, 9, p. 3275-3281 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendal, C., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 23 May 2013, In: European Journal of Endocrinology. 169, p. 187-201 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A dose-equivalent comparison of the effects of continuous subcutaneous glucagon-like peptide 2 (GLP-2) infusions versus meal related GLP-2 injections in the treatment of short bowel syndrome (SBS) patients
Naimi, R. M., Madsen, K. B., Askov-Hansen, C., Brandt, C. F., Hartmann, Bolette, Holst, Jens Juul, Mortensen, P. B. & Jeppesen, Palle Bekker, 10 Jun 2013, In: Regulatory Peptides. 184, 10, p. 47-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute effects of continuous infusions of glucagon-like peptide (GLP)-1, GLP-2 and the combination (GLP-1+GLP-2) on intestinal absorption in short bowel syndrome (SBS) patients. A placebo-controlled study
Madsen, K. B., Askov-Hansen, C., Naimi, R. M., Brandt, C. F., Hartmann, Bolette, Holst, Jens Juul, Mortensen, P. B. & Jeppesen, Palle Bekker, 10 Jun 2013, In: Regulatory Peptides. 184, 10, p. 30-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular-scale simulation of electroluminescence in a multilayer white organic light-emitting diode
Mesta, M., Carvelli, M., de Vries, R. J., van Eersel, H., van der Holst, J. J. M., Schober, M., Furno, M., Lüssem, B., Leo, K., Loebl, P., Coehoorn, R., Bobbert, P. A. & Holst, Jens Juul, Jul 2013, In: Nature Materials. 12, 7, p. 652-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of tumor necrosis factor-alpha infusion on the incretin effect in healthy volunteers
Nielsen, S. T., Lehrskov-Schmidt, L., Krogh-Madsen, R., Solomon, T., Lehrskov-Schmidt, L., Holst, Jens Juul & Møller, K., 31 Jul 2013, In: Diabetes - Metabolism: Research and Reviews (Online). 29, 8, p. 655-663 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormones and the satiation signal
Holst, Jens Juul, Sep 2013, In: International journal of obesity (2005). 37, 9, p. 1161-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic safety of GLP-1-based therapeutic agents: further insights from rodent studies?
Holst, Jens Juul, Sep 2013, In: Diabetologia. 56, 9, p. 1869-72 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A pilot study examining the relationship among Crohn disease activity, glucagon-like peptide-2 signalling and intestinal function in pediatric patients
Sigalet, D. L., Kravarusic, D., Butzner, D., Hartmann, Bolette, Holst, Jens Juul & Meddings, J., Oct 2013, In: Canadian Journal of Gastroenterology. 27, 10, p. 587-92 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety
Deacon, Carolyn F. & Holst, Jens Juul, Oct 2013, In: Expert Opinion on Pharmacotherapy. 14, 15, p. 2047-58 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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