Lærke Smidt Gasbjerg

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Research field: translational area between molecular pharmacology, clinical physiology and modern imaging techniques focusing on the endocrine system, cardiovascular system, and metabolism.

Expertise: peptide gut hormones related to nutrient metabolism involving ligand-receptor interactions, physiological actions, pathophysiological implications, and therapeutic potential. 

Key words: Peptide hormones, incretin effect, hormone physiology, pharmacology, GIP, GLP-1, GLP-2

Possible conflicts of interest

Co-founder of Antag Therapeutics, CVR 38402056

Selected publications

1. Published

   GLP-1 and GIP receptor signaling in beta cells – A review of receptor interactions and co-stimulation

   Mayendraraj, A., Rosenkilde, Mette & Gasbjerg, Lærke Smidt, 2022, In: Peptides. 151, p. 1-10 170749.

   Research output: Contribution to journal › Journal article › peer-review

2. Published

   Worsening Postural Tachycardia Syndrome Is Associated With Increased Glucose-Dependent Insulinotropic Polypeptide Secretion

   Breier, N. C., Paranjape, S. Y., Scudder, S., Mehr, S. E., Diedrich, A., Flynn, C. R., Okamoto, L. E., Hartmann, Bolette, Gasbjerg, Lærke Smidt & Shibao, C. A., 2022, In: Hypertension. 79, 5, p. e89-e99

   Research output: Contribution to journal › Journal article › peer-review

3. Published

   Effects of endogenous GIP in patients with type 2 diabetes

   Stensen, S., Gasbjerg, Lærke Smidt, Krogh, L. L., Skov-Jeppesen, Kirsa, wbf943, wbf943, Jensen, M. H., Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 33-45

   Research output: Contribution to journal › Journal article › peer-review

4. Published

   GIP(3-30)NH₂ is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study

   Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Hartmann, Bolette, Lanng, A. R., wbf943, wbf943, Gabe, M. B. N., Dela, Flemming, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, Feb 2018, In: Diabetologia. 61, 2, p. 413-423

   Research output: Contribution to journal › Journal article › peer-review

5. Published

   Evaluation of the incretin effect in humans using GIP and GLP-1 receptor antagonists

   Gasbjerg, Lærke Smidt, Bergmann, N. C., Stensen, S., Christensen, Mikkel Bring, Rosenkilde, Mette, Holst, Jens Juul, Nauck, M. & Knop, Filip Krag, 2020, In: Peptides. 125, 10 p., 170183.

   Research output: Contribution to journal › Review › peer-review