Lærke Smidt Gasbjerg
Postdoc, Assistant Professor
Molecular and Translational Pharmacology
Blegdamsvej 3, 2200 København N.
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
Research field: translational area between molecular pharmacology, clinical physiology and modern imaging techniques focusing on the endocrine system, cardiovascular system, and metabolism.
Expertise: peptide gut hormones related to nutrient metabolism involving ligand-receptor interactions, physiological actions, pathophysiological implications, and therapeutic potential.
Key words: Peptide hormones, incretin effect, hormone physiology, pharmacology, GIP, GLP-1, GLP-2
Possible conflicts of interest
Co-founder of Antag Therapeutics, CVR 38402056
Selected publications
- Published
GLP-1 and GIP receptor signaling in beta cells – A review of receptor interactions and co-stimulation
Mayendraraj, A., Rosenkilde, Mette & Gasbjerg, Lærke Smidt, 2022, In: Peptides. 151, p. 1-10 170749.Research output: Contribution to journal › Journal article › peer-review
- Published
Worsening Postural Tachycardia Syndrome Is Associated With Increased Glucose-Dependent Insulinotropic Polypeptide Secretion
Breier, N. C., Paranjape, S. Y., Scudder, S., Mehr, S. E., Diedrich, A., Flynn, C. R., Okamoto, L. E., Hartmann, Bolette, Gasbjerg, Lærke Smidt & Shibao, C. A., 2022, In: Hypertension. 79, 5, p. e89-e99Research output: Contribution to journal › Journal article › peer-review
- Published
Effects of endogenous GIP in patients with type 2 diabetes
Stensen, S., Gasbjerg, Lærke Smidt, Krogh, L. L., Skov-Jeppesen, Kirsa, wbf943, wbf943, Jensen, M. H., Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 33-45Research output: Contribution to journal › Journal article › peer-review
- Published
GIP(3-30)NH2 is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study
Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Hartmann, Bolette, Lanng, A. R., wbf943, wbf943, Gabe, M. B. N., Dela, Flemming, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, Feb 2018, In: Diabetologia. 61, 2, p. 413-423Research output: Contribution to journal › Journal article › peer-review
- Published
Evaluation of the incretin effect in humans using GIP and GLP-1 receptor antagonists
Gasbjerg, Lærke Smidt, Bergmann, N. C., Stensen, S., Christensen, Mikkel Bring, Rosenkilde, Mette, Holst, Jens Juul, Nauck, M. & Knop, Filip Krag, 2020, In: Peptides. 125, 10 p., 170183.Research output: Contribution to journal › Review › peer-review
ID: 37775779
Most downloads
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271
downloads
GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release
Research output: Contribution to journal › Journal article › peer-review
Published -
258
downloads
Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Research output: Contribution to journal › Journal article › peer-review
Published -
111
downloads
Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats
Research output: Contribution to journal › Journal article › peer-review
Published