Jens Juul Holst

Jens Juul Holst

Professor


  1. Published
  2. Published

    Evaluation of the incretin effect in humans using GIP and GLP-1 receptor antagonists

    Gasbjerg, Lærke Smidt, Bergmann, N. C., Stensen, S., Christensen, Mikkel Bring, Rosenkilde, Mette, Holst, Jens Juul, Nauck, M. & Knop, Filip Krag, 2020, In: Peptides. 125, 10 p., 170183.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Evaluation of ß-cell secretory capacity using glucagon-like peptide-1

    Visbøll, T., Toft-Nielsen, M., Krarup, T., Madsbad, S., Dinesen, B. & Holst, Jens Juul, 2000, In: Diabetes Care. 23, p. 807-812

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Evidence for Relationship Between Early Dumping and Postprandial Hypoglycemia After Roux-en-Y Gastric Bypass

    Øhrstrøm, C. C., Worm, Dorte, Kielgast, U. L., Holst, Jens Juul & Hansen, D. L., 2020, In: Obesity Surgery. 30, 3, p. 1038-1045

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity

    Raben, Anne, Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, In: American Journal of Physiology: Endocrinology and Metabolism. 267, 4 part 1, p. E549-E559 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity

    Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Physiol.. 267, p. E549-E559

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Evidence for an endocrine pancreatico-gastric axis: The role of pancreatic polypeptide in gastric emptying and short term metabolic control

    Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Holst, Jens Juul, Hilsted, L. & Hellström, P. M., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 5241-5246

    Research output: Contribution to journalJournal articleResearch

  8. Published

    Evidence for paracrine/autocrine regulation of GLP-1-producing cells

    Kappe, C., Zhang, Q., Holst, Jens Juul, Nyström, T. & Sjöholm, A., 15 Nov 2013, In: A J P: Cell Physiology (Online). 305, 10, p. C1041-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Evidence of Extrapancreatic Glucagon Secretion in Man

    Lund, Asger Bach, Bagger, J. I., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M., Hartmann, Bolette, Mathiesen, Elisabeth, Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Rehfeld, Jens Frederik, Hornburg, D., Meissner, F., Mann, Matthias, Larsen, S., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Mar 2016, In: Diabetes. 65, 3, p. 585-597 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids

    Albrechtsen, Nicolai Jacob Wewer, Færch, K., Jensen, T. M., Witte, D. R., Pedersen, Jens, Mahendran, Y., Jonsson, Anna Elisabet, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Torekov, Signe Sørensen, Lauritzen, T., Pedersen, Oluf Borbye, Knop, Filip Krag, Hansen, Torben, Jørgensen, M. E., Vistisen, D. & Holst, Jens Juul, 2018, In: Diabetologia. 61, 3, p. 671-680

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes

    Torekov, Signe Sørensen, Larsen, L. H., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Holst, Jens Juul, Madsen, O. D., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Diabetes. 54, 7, p. 2261-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Evidence of an association between the Arg72-allele of the peptide YY (PYY) and increased risk of type 2 diabetes

    Torekov, S. S., Larsen, L. H., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Holst, Jens Juul, Madsen, O. D., Hansen, T. & Pedersen, O., 2005, In: Diabetes. 54, p. 2261-2265

    Research output: Contribution to journalJournal articleResearch

  13. Published

    Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding.

    Korner, J., Bessler, M., Inabnet, W., Taveras, C. & Holst, Jens Juul, 2007, In: Surgery for Obesity and Related Diseases. 3, 6, p. 597-601 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Exaggerated release and preserved insulinotropic action of glucagon-like peptide-1 underlie insulin hypersecretion in glucose-tolerant individuals after Roux-en-Y gastric bypass

    Dirksen, C., Bojsen-Møller, K. N., Jørgensen, N. B., Jacobsen, S. H., Kristiansen, V. B., Naver, L. S., Hansen, D. L., Worm, Dorte, Holst, Jens Juul & Madsbad, Sten, 2013, In: Diabetologia. 56, 12, p. 2679-2687

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Exaggerated secretion of glucagon-like peptide-1 (GLP-1) could cause reactive hypoglycaemia

    Toft-Nielsen, M., Madsbad, Sten & Holst, Jens Juul, 1998, In: Diabetologia. 41, 10, p. 1180-1186 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Examining the effects of hyperglycemia on pancreatic endocrine function in humans: evidence for in vivo glucotoxicity

    Solomon, T. P. J., Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul & Pedersen, Bente Klarlund, Dec 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 12, p. 4682-91 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Exenatide augments first and second phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes

    Fehse, F., Trautmann, M., Holst, Jens Juul, Halseth, A. E., Nanyakkara, N., Nielsen, L., Fineman, M. S. D., Kim, D. D. & Nauck, M. A., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 5991-5997

    Research output: Contribution to journalJournal articleResearch

  18. Published

    Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes

    Fehse, F., Trautmann, M., Holst, Jens Juul, Halseth, A. E., Nanayakkara, N., Nielsen, L. L., Fineman, M. S., Kim, D. D. & Nauck, M. A., Nov 2005, In: The Journal of clinical endocrinology and metabolism. 90, 11, p. 5991-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Exenatide once weekly for alcohol use disorder investigated in a randomized, placebo-controlled clinical trial

    Klausen, M. K., Jensen, M. E., Møller, M., le Dous, N., Jensen, A-M. Ø., Zeeman, V. A., Johannsen, C-F., Lee, A. M., Thomsen, G. K., Macoveanu, J., Fisher, P. M., Gillum, M. P., Jørgensen, N. R., Bergmann, M. L., Enghusen Poulsen, H., Becker, U., Holst, J. J., Benveniste, H., Volkow, N. D., Vollstädt-Klein, S. & 5 others, Miskowiak, Kamilla, Ekstrøm, Claus Thorn, Knudsen, Gitte Moos, Visboll, T. & Fink-Jensen, Anders, 2022, In: JCI insight. 19, 20 p., e159863.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction

    Lønborg, Jacob Thomsen, Vejlstrup, N., Kelbæk, H., Bøtker, H. E., Kim, W. Y., Mathiasen, A. B., Jørgensen, E., Helqvist, S., Saunamäki, K., Clemmensen, P., Holmvang, Lene, Thuesen, L., Krusell, L. R., Jensen, J. S., Køber, Lars Valeur, Treiman, M., Holst, Jens Juul & Engstrøm, Thomas, 2011, In: European Heart Journal. 33, 12, p. 1491-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Exendin-4 and exendin (9-39)NH*U2-agonist and antagonist, respectively, at the rat parietal cell receptor for glucagon-like peptide-1 (7-36)NH*U2

    Schepp, W., Schmidtler, J. & Holst, Jens Juul, 1994, In: Eur. J. Pharmacol.. 269, p. 183-191

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats.

    Simonsen, L., Pilgaard, S., Orskov, C., Rosenkilde, Mette, Hartmann, B., Holst, Jens Juul & Deacon, Carolyn F., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G288-95

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

    Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., Apr 2006, In: Diabetologia. 49, 4, p. 706-12 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

    Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Diabetologia. 49, 4, p. 706-712 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Exercise alone and in combination with liraglutide improves cardiorespiratory fitness and physical functioning during weight loss maintenance

    Jensen, Simon Birk Kjær, Janus, C., Lundgren, J. R., Juhl, C. R., Blond, Martin Bæk, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2020, In: Diabetologia. 63, SUPPL 1, p. S290-S290 1 p., 604.

    Research output: Contribution to journalConference abstract in journalResearch

  26. E-pub ahead of print
  27. Published

    Exercise-related hypoglycaemia induces QTc-interval prolongation in individuals with type 1 diabetes

    Hagelqvist, P. G., Andersen, A., Maytham, K. B., Andreasen, C. R., Engberg, S., Lindhardt, T. B., Faber, Jens, Holst, Jens Juul, Forman, Julie Lyng, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 25, 5, p. 1186-1195 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Exogenous GLP-2 has only marginal effects on weaning-induced intestinal adaption in piglets

    le Huërou-Luron, I., Petersen, Y. M., Hartmann, B., Holst, Jens Juul & Sangild, Per Torp, 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 164-166 3 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  29. Published

    Exogenous glucagon-like peptide-2 (GLP-2) augments GLP-2 receptor mRNA and maintains proglucagon mRNA levels in resected rats

    Koopmann, M. C., Nelson, D. W., Murali, S. G., Liu, X., Brownfield, M. S., Holst, Jens Juul & Ney, D. M., 30 Apr 2008, In: Journal of Parenteral and Enteral Nutrition. 32, 3, p. 254-65 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Exogenous glucagon-like peptide-2 (GLP-2) augments GLP-2 receptor mRNA and maintains proglucagon mRNA levels in resected rats

    Koopmann, M. C., Nelson, D. W., Murali, S. G., Liu, X. W., Brownfield, M. S., Holst, Jens Juul & Ney, D. M., 2008, In: Journal of Parenteral and Enteral Nutrition. 32, 3, p. 254-265 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine

    Kissow, Hannelouise, Viby, N., Hartmann, Bolette, Holst, Jens Juul, Timm, M., Thim, L. & Poulsen, Steen Seier, 2012, In: Cancer Chemotherapy and Pharmacology. Supplement. 70, 1, p. 39-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Exogenous secretin decreases ad libitum food intake and exhibits a biphasic effect on supraclavicular brown adipose tissue activity in healthy men

    Bentzen, M. J., Heimburger, S. M. N., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 211-211 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  33. Published

    Exploratory analysis of eating- and physical activity-related outcomes from a randomized controlled trial for weight loss maintenance with exercise and liraglutide single or combination treatment

    Jensen, Simon Birk Kjær, Janus, C., Lundgren, J. R., Juhl, C. R., Sandsdal, Rasmus Michael, Olsen, L. M., Andresen, A., Borg, S. A., Jacobsen, I. C., Finlayson, G., Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2022, In: Nature Communications. 13, 1, 11 p., 4770.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Exploring the GLP-1-GLP-1R axis in porcine pancreas and gastrointestinal tract in vivo by ex vivo autoradiography

    Manell, E., Puuvuori, E., Svensson, A., Velikyan, I., Hulsart-Billström, G., Hedenqvist, P., Holst, Jens Juul, Jensen Waern, M. & Eriksson, O., 2021, In: B M J Open Diabetes Research & Care. 9, 10 p., e002083.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Expression Profile of the GLP-1 Receptor in the Gastrointestinal Tract and Pancreas in Adult Female Mice

    Grunddal, Kaare Villum, Jensen, E. P., Ørskov, Cathrine, Andersen, Daniel Bjørklund, Windeløv, Johanne Agerlin, Poulsen, Steen Seier, Rosenkilde, M. M., Knudsen, L. B., Pyke, C. & Holst, Jens Juul, 2022, In: Endocrinology. 163, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Expression of mRNA for proglucagon and glucagon-like peptide-2 (GLP-2) receptor in the ruminant gastrointestinal tract and the influence of energy intake

    Taylor-Edwards, C. C., Burrin, D. G., Matthews, J. C., McLeod, K. R., Holst, Jens Juul & Harmon, D. L., 1 Oct 2010, In: Domestic Animal Endocrinology. 39, 3, p. 181-93 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Extracellular Fluid Volume Expansion Uncovers a Natriuretic Action of GLP-1: A Functional GLP-1–Renal Axis in Man

    Asmar, A., Cramon, P. K., Simonsen, L., Asmar, M., Sorensen, Charlotte Mehlin, Madsbad, Sten, Moro, C., Hartmann, Bolette, Jensen, B. L., Holst, Jens Juul & Bülow, J., Jul 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2509–2519

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Extreme duration exercise affects old and younger men differently

    Frandsen, J., Sahl, R. E., Rømer, T., Thunestvedt Hansen, M., Nielsen, A. B., Lie-Olesen, M. M., Rasmusen, H. K., Søgaard, D., Ingersen, A., Rosenkilde, M., Westerterp, K., Holst, J. J., Andersen, J. L., Markowski, A. R., Blachnio-Zabielska, A., Clemmensen, C., Sacchetti, M., Cataldo, A., Traina, M., Larsen, S. & 2 others, Dela, Flemming & Helge, Jørn Wulff, 2022, In: Acta Physiologica. 235, 3, e13816.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Extrinsic control of the release of galanin and VIP from intrinsic nerves of isolated, perfused porcine ileum

    Messel, T., Harling, H., Poulsen, S. S., Bersani, M. & Holst, Jens Juul, 1992, In: Regulatory Peptides. 38, p. 179-198

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Extrinsic control of the release of galanin and VIP from intrinsic nerves of isolated, perfused, porcine ileum

    Messell, T., Harling, H., Poulsen, Steen Seier, Bersani, M. & Holst, Jens Juul, 9 Apr 1992, In: Regulatory Peptides. 38, 3, p. 179-98 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Factors associated with favorable changes in food preferences after bariatric surgery

    Nielsen, M. S., Christensen, Bodil Just, Ritz, C., Holm, Lotte, Lunn, Susanne, Tækker, L., Schmidt, J. B., Bredie, Wender, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hilbert, A., le Roux, C. W. & Sjödin, Anders Mikael, 2021, In: Obesity Surgery. 31, 8, p. 3514-3524 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Fast acting nervous regulation of immunoglobulin A secretion from isolated perfused porcine ileum

    Schmidt, P. T., Eriksen, L., Loftager, M., Rasmussen, T. N. & Holst, Jens Juul, 1999, In: Gut. 45, p. 679-685

    Research output: Contribution to journalJournal articleResearch

  43. Published

    Fast pouch emptying, delayed small intestinal transit, and exaggerated gut hormone responses after Roux-en-Y gastric bypass

    Dirksen, C., Damgaard, Morten, Bojsen-Møller, K. N., Jørgensen, N. B., Kielgast, U., Jacobsen, S. H., Naver, L. S., Worm, Dorte, Holst, Jens Juul, Madsbad, Sten, Hansen, D. L. & Madsen, J. L., Apr 2013, In: Neurogastroenterology and Motility. 25, 4, p. 346-e255 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Fasting and oral glucose-stimulated levels of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are highly familial traits

    Gjesing, A. M. P., Ekstrøm, Claus Thorn, Eiberg, Hans Rudolf Lytchoff, Urhammer, S. A., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Teis Schjals, 2012, In: Diabetologia. 55, 5, p. 1338-1345 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Fasting plasma GLP-1 associates with overweight/obesity and cardiometabolic risk factors in children and adolescents

    Stinson, Sara, Jonsson, Anna Elisabet, Lund, M. A. V., Frithioff-Bøjsøe, C., Holm, L. A., Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, Thorkild I.A., Holst, Jens Juul, Christiansen, M., Holm, Jens-Christian, Hartmann, Bolette & Hansen, Torben, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 6, p. 1718-1727

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Fatty Liver Among Adolescent Offspring of Women With Type 1 Diabetes (the EPICOM Study)

    Knorr, S., Bytoft, B., Lohse, Z., Boisen, A. B., Clausen, Tine Dalsgaard, Jensen, R. B., Damm, Peter, Beck-Nielsen, H., Holst, Jens Juul, Hartmann, Bolette, Moller, H. J., Hojlund, K., Gravholt, C. H. & Jensen, D. M., 2019, In: Diabetes Care. 42, 8, p. 1560-1568

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Feast or famine - are GLP-1 and ghrelin secretion intertwined?

    Djurhuus, C. B., Hansen, T. K., Holst, Jens Juul & Schmitz, O., Jul 2002, In: Hormone and Metabolic Research. Supplement. 34, 7, p. 353-4 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Fedtvaevet og insulin-resistens: resistin og adiponectin.

    Holst, Jens Juul & Binderup, M., 2002, In: Ugeskrift for læger. 164, 16, p. 2173-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Feedback suppression of meal-induced glucagon-like peptide-1 (GLP-1) secretion mediated through elevations in intact GLP-1 caused by dipeptidyl peptidase-4 inhibition: a randomized, prospective comparison of sitagliptin and vildagliptin treatment

    Baranov, O., Kahle, M., Deacon, Carolyn F., Holst, Jens Juul & Nauck, M. A., Nov 2016, In: Diabetes, Obesity and Metabolism. 18, 11, p. 1100-1109 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs

    Stoll, B., Price, P. T., Reeds, P. J., Chang, X., Henry, J. F., Goudoever, J. B. V., Holst, Jens Juul & Burrin, D. G., 2006, In: Journal of Parenteral and Enteral Nutrition. 30, 1, p. 32-39 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs

    Stoll, B., Price, P. T., Reeds, P. J., Chang, X., Henry, J. F., van Goudoever, J. B., Holst, Jens Juul & Burrin, D. G., 3 Jan 2006, In: Journal of Parenteral and Enteral Nutrition. 30, 1, p. 32-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Fiber mixture-specific effect on distal colonic fermentation and metabolic health in lean but not in prediabetic men

    Canfora, E. E., Hermes, G. D. A., Mueller, M., Bastings, J., Vaughan, E. E., van den Berg, M. A., Holst, Jens Juul, Venema, K., Zoetendal, E. G. & Blaak, E. E., 2022, In: Gut Microbes. 14, 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Foetal proglucagon processing in relation to adult appetite control: lessons from a transplantable rat glucagonoma with severe anorexia

    Jensen, P. B., Larsen, P. J., Karlsen, C., Jensen, H. I., Holst, Jens Juul & Madsen, O. D., Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl. 1, p. 60-68 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Follistatin secretion is enhanced by protein, but not glucose or fat ingestion in obese persons independently of previous gastric bypass surgery

    Bojsen-Møller, K. N., Svane, M. S., Jensen, Christian Zinck, Kjeldsen, Sasha Alexandra Sampson, Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer & Madsbad, Sten, 2021, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 320, 5, p. G753-G758

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    For debate: Are antidiabetic actions of DPP-IV inhibitors mediated by glucagon-like peptide- 1?

    Holst, Jens Juul & Deacon, Carolyn F., 2005, In: Diabetologia. 48, p. 612-615

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Fortifying a meal with oyster mushroom powder beneficially affects postprandial glucagon-like peptide-1, non-esterified free fatty acids and hunger sensation in adults with impaired glucose tolerance: a double-blind randomized controlled crossover trial

    Dicks, L., Jakobs, L., Sari, M., Hambitzer, R., Ludwig, N., Simon, M., Stehle, P., Stoffel-Wagner, B., Helfrich, H., Ahlborn, J., Rühl, M., Hartmann, Bolette, Holst, Jens Juul & Ellinger, S., 2022, In: European Journal of Nutrition. 61, p. 687–701

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

    Højberg, P. V., Vilsbøll, Tina, Rabøl, R., Knop, Filip Krag, Bache, M., Krarup, T., Holst, Jens Juul & Madsbad, Sten, 2008, In: Diabetologia. 52, 2, p. 199-207 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes

    Højberg, P. V., Vilsbøll, T., Zander, M., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, Nov 2008, In: Diabetic Medicine Online. 25, 11, p. 1268-75 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function

    Kielgast, U., Krarup, T., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jul 2011, In: Diabetes Care. 34, 7, p. 1463-1468 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Four weeks supplementation with Lactobacillus paracasei subsp. paracasei L. casei W8® shows modest effect on triacylglycerol in young healthy adults

    Bjerg, A. T., Kristensen, M. B., Ritz, C., Stark, K. D., Holst, Jens Juul, Leser, T. D., Wellejus, A. & Astrup, A., 2015, In: Beneficial Microbes. 6, 1, p. 29-39 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Four weeks treatment with the GLP-1 receptor analogue liraglutide lowers liver fat and concomitantly circulating glucagon in individuals with overweight

    Svane, M. S., Johannesen, H. H., Hansen, Adam Espe, Martinussen, C., Bojsen-Møller, K. N., Hansen, M. L., Deacon, Carolyn F., Keller, S. H., Klausen, Thomas Levin, Loft, A., Kjær, Andreas, Löfgren, J., Madsbad, Sten, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: International Journal of Obesity. 46, 11, p. 2058–2062 8 p.

    Research output: Contribution to journalLetterResearchpeer-review

  62. Published

    Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD

    Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2009, In: Bone. 45, 5, p. 833-42 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    From the Incretin Concept and the Discovery of GLP-1 to Today's Diabetes Therapy

    Holst, Jens Juul, 2019, In: Frontiers in Endocrinology. 10, 10 p., 260.

    Research output: Contribution to journalReviewResearchpeer-review

  64. Published

    Fructose intervention for 12 weeks does not impair glycemic control or incretin hormone responses during oral glucose or mixed meal tests in obese men

    Matikainen, N., Söderlund, S., Björnson, E., Bogl, L. H., Pietiläinen, K. H., Hakkarainen, A., Lundbom, N., Eliasson, B., Räsänen, S. M., Rivellese, A., Patti, L., Prinster, A., Riccardi, G., Després, J., Alméras, N., Holst, Jens Juul, Deacon, Carolyn F., Borén, J. & Taskinen, M., Jun 2017, In: Nutrition, Metabolism & Cardiovascular Diseases. 27, 6, p. 534-542 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans

    Kuhre, Rune Ehrenreich, Gribble, F. M., Hartmann, Bolette, Reimann, F., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik & Holst, Jens Juul, 1 Apr 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 306, 7, p. G622-30 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Functional Magnetic Resonance Imaging (fMRI) of Neural Responses to Visual and Auditory Food Stimuli Pre and Post Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG)

    Baboumian, S., Pantazatos, S. P., Kothari, S., McGinty, J., Holst, Jens Juul & Geliebter, A., 2019, In: Neuroscience. 409, p. 290-298

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Functional and immunohistochemical evaluation of porcine neonatal islet-like cell clusters.

    Nielsen, T. B., Yderstraede, K. B., Schrøder, H. D., Holst, Jens Juul, Brusgaard, K. & Beck-Nielsen, H., 2003, In: Cell Transplantation. 12, 1, p. 13-25 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate

    Amin, H., Holst, Jens Juul, Hartmann, B., Wallace, L., Wright, J. & Sigalet, D. L., 2008, In: Pediatrics. 121, 1, p. E180-E186 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Functional ontogeny of the proglucagon-derived peptide axis in the premature human neonate

    Amin, H., Holst, Jens Juul, Hartmann, Bolette, Wallace, L., Wright, J. & Sigalet, D. L., Jan 2008, In: Pediatrics. 121, 1, p. e180-6

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction

    Holst, Birgitte, Egerod, Kristoffer Lihme, Jin, C., Petersen, P. S., Østergaard, M. V., Hald, J., Sprinkel, A. M. E., Størling, J., Mandrup-Poulsen, Thomas, Holst, Jens Juul, Thams, P., Orskov, C., Wierup, N., Sundler, F., Madsen, O. D. & Schwartz, Thue W., 2009, In: Endocrinology. 150, 6, p. 2577-85 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    GIP affects hepatic fat and brown adipose tissue thermogenesis, but not white adipose tissue transcriptome in T1D

    Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergman, N. C., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Havelund, J. F., Gorshkov, V., Kjeldsen, F., Færgeman, N. J. K., Madsen, M. R., Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 12, p. 3261–3274

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in HNF1A Diabetes

    Christensen, A. S., Haedersdal, S., Storgaard, H., Rose, K., Hansen, N. L., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2019, In: Diabetes. 68, Suppl. 1, 1 p., 981-P.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  73. Published

    GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in Hepatocyte Nuclear Factor 1 alpha Mutation Carriers

    Christensen, A. S., Haedersdal, S., Storgaard, H., Rose, K., Hansen, N. L., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes. 69, 9, p. 1989-2002 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    GIP and GLP-1 Receptor Antagonism During a Meal in Healthy Individuals

    Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, wbf943, wbf943, Veedfald, Simon, Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 3, p. e725-e738 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    GIP and GLP-1 after oral glucose in postmenopausal women with impaired glucose tolerance.

    Ahrén, B., Larsson, H. & Holst, Jens Juul, 1997, In: European Journal of Endocrinology. 137, p. 127-131

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment

    Gabe, M. B. N., Skov-Jeppesen, Kirsa, Gasbjerg, Lærke Smidt, Schiellerup, S. P., Martinussen, C., Gadgaard, S., Boer, G. A., Oeke, J., Pedersen, Lola Julie Torz, Veedfald, Simon, Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: Pharmacological Research. 176, 106058.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    GIP as a Therapeutic Target in Diabetes and Obesity: Insight From Incretin Co-agonists

    Holst, Jens Juul & Rosenkilde, M. M., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 8, p. E2710-E2716 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  78. Published

    GIP does not potentiate the antidiabetic effects of GLP-1 in hyperglycemic patients with type 2 diabetes

    Mentis, N., Vardarli, I., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Theodorakis, M., Meier, J. J. & Nauck, M. A., 2011, In: Diabetes. 60, 4, p. 1270-1276 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    GIP infusion in patients with type 1 diabetes seems to attenuate post-prandial glucose excursions after prandial insulin over-dose and physical activity

    Hoe, B., Heimburger, S. M. N., Gasbjerg, L. S., Lanng, A. R., Lynggaard, M. B., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Lund, A., Engberg, S., Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Diabetologia. 63, Suppl. 1, p. S117 1 p., 232.

    Research output: Contribution to journalConference abstract in journalResearch

  80. Published

    GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet

    McClean, P. L., Irwin, N., Cassidy, R. S., Holst, Jens Juul, Gault, V. A. & Flatt, P. R., Dec 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 6, p. E1746-55

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet

    McClean, P. L., Irwin, N., Cassidy, R. S., Holst, Jens Juul, Gault, V. A. & Flatt, P. R., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 6, p. E1746-E1755

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    GIP receptor deletion in mice confers resistance to HFD-induced obesity via alterations in energy expenditure and adipose tissue lipid metabolism

    Boer, G. A., Keenan, S. N., Miotto, P. M., Holst, Jens Juul & Watt, M. J., 2021, In: American Journal of Physiology: Endocrinology and Metabolism. 320, 4, p. E835-E845 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published
  84. Published

    GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release

    wbf943, wbf943, Gabe, M. N., Gasbjerg, Lærke Smidt, Christiansen, Charlotte Bayer, Svendsen, B., Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, 2017, In: Biochemical Pharmacology. 131, p. 78-88

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published
  86. Published

    GIP-(3-42) does not antagonize insulinotropic effects of GIP at physiological concentrations.

    Deacon, Carolyn F., Plamboeck, A., Rosenkilde, Mette, de Heer, J. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 3, p. E468-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    GIP-induced vasodilation in human adipose tissue involves capillary recruitment

    Asmar, M., Asmar, A., Simonsen, L., Dela, Flemming, Holst, Jens Juul & Bulow, J., Jun 2019, In: Endocrine Connections. 8, 6, p. 806-813

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    GLP-1: physiological effects and potential therapeutic applications

    Aaboe, K., Krarup, T., Madsbad, Sten & Holst, Jens Juul, Nov 2008, In: Diabetes, Obesity and Metabolism Online. 10, 11, p. 994-1003 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans

    Schjoldager, B. T., Mortensen, P. E., Christiansen, J., Ørskov, Cathrine & Holst, Jens Juul, May 1989, In: Digestive Diseases and Sciences. 34, 5, p. 703-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    GLP-1 - Incretin and pleiotropic hormone with pharmacotherapy potential. Increasing secretion of endogenous GLP-1 for diabetes and obesity therapy

    Holst, Jens Juul, Jepsen, Sara Lind & Modvig, Ida Marie, 2022, In: Current Opinion in Pharmacology. 63, p. 1-7 102189.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    GLP-1 Amidation Efficiency Along the Length of the Intestine in Mice, Rats and Pigs and in GLP-1 Secreting Cell Lines

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Svendsen, B., Hartmann, Bolette & Holst, Jens Juul, 31 Jan 2014, In: Peptides. 55, p. 52-57 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    GLP-1 Receptor Agonist Treatment in Morbid Obesity and Type 2 Diabetes Due to Pathogenic Homozygous Melanocortin-4 Receptor Mutation: A Case Report

    Iepsen, E. W., Have, C. T., Veedfald, Simon, Madsbad, Sten, Holst, Jens Juul, Grarup, Niels, Pedersen, Oluf Borbye, Brandslund, I., Holm, Jens-Christian, Hansen, Torben & Torekov, Signe Sørensen, 2020, In: Cell Reports Medicine. 1, 1, 8 p., 100006.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    GLP-1 Restores Altered Insulin and Glucagon Secretion in Posttransplantation Diabetes

    Halden, T. A. S., Egeland, E. J., Åsberg, A., Hartmann, A., Midtvedt, K., Khiabani, H. Z., Holst, Jens Juul, Knop, Filip Krag, Hornum, Mads, Feldt-Rasmussen, Bo & Jenssen, T., 23 Feb 2016, In: Diabetes Care. 39, p. 617-24

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    GLP-1 Val8: A Biased GLP-1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats

    van der Velden, W. J. C., Smit, F. X., Christiansen, Charlotte Bayer, Møller, T. C., Hjortø, Gertrud Malene, Larsen, Olav, Schiellerup, S. P., Bräuner, Hans, Holst, Jens Juul, Hartmann, Bolette, Frimurer, Thomas Michael & Rosenkilde, Mette, 2021, In: ACS Pharmacology & Translational Science. 4, 1, p. 296-313 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine

    Mortensen, K., Christensen, L. L., Holst, Jens Juul & Ørskov, Cathrine, 2003, In: Regulatory Peptides. 114, 2-3, p. 189-96 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    GLP-1 and GLP-2 act in concert to inhibit fasted, but not fed, small bowel motility in the rat.

    Bozkurt, A., Näslund, E., Holst, Jens Juul & Hellström, P. M., 2002, In: Regulatory Peptides. 107, 1-3, p. 129-35 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    GLP-1 and Intestinal Diseases

    Dal, Jenna Elizabeth Hunt, Holst, Jens Juul, Jeppesen, Palle Bekker & Kissow, Hannelouise, 2021, In: Biomedicines. 9, 4, 14 p., 383.

    Research output: Contribution to journalReviewResearchpeer-review

  98. Published

    GLP-1 as a Mediator in the Remission of Type 2 Diabetes After Gastric Bypass and Sleeve Gastrectomy Surgery

    Madsbad, Sten & Holst, Jens Juul, Oct 2014, In: Diabetes. 63, 10, p. 3172-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    GLP-1 baseret behandling af diabetes og svær overvægt

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2015, In: BestPractice. 9, 4, p. 10-12 3 p.

    Research output: Contribution to journalJournal articleCommunication

  100. Published

    GLP-1 defects in diabetes

    Janus, C., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2 Feb 2015

    Research output: Other contributionNet publication - Internet publicationResearchpeer-review

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