Michael Jonathan Davies

Michael Jonathan Davies

Professor

ORCID: 0000-0002-5196-6919

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  1. Published

    Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: Three year follow-up of a cluster randomised controlled trial in primary care

    Khunti, K., Gray, L. J., Skinner, Timothy, Carey, M. E., Realf, K., Dallosso, H., Fisher, H., Campbell, M., Heller, S. & Davies, Michael Jonathan, 9 Jun 2012, In: BMJ (Online). 344, 7860, e2333.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial

    Davies, Michael Jonathan, Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In: BMJ. 336, 7642, p. 491-495 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models

    Chen, Z., Kondrashina, A., Greco, I., Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael Jonathan, 2019, In: Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings

    Zacharias, T., Flouda, K., Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael Jonathan, 2020, In: Biochemical Pharmacology. 173, 14 p., 113631.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice: [Meeting Abstract]

    Zacharias, T., Flouda, K., Jepps, T., Christoffersen, Christina, Pedersen, T., Gammelgaard, Bente, Schiesser, C. & Davies, Michael Jonathan, 20 May 2018, In: Free Radical Biology & Medicine. 120, S1, p. S68-S68 P-79.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  6. Published

    Endothelial nitric oxide synthase plays a protective role in endothelial cells and cardiomyocytes against myocardial infarction

    Gentile, C., Kesteven, S., Wu, J., Davies, Michael Jonathan, Bursill, C., Feneley, M. & Figtree, G., 2020, In: Journal of Molecular and Cellular Cardiology. 140, p. 31-31

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  7. Published

    Enzymatic cross-linking of collagens in organ fibrosis - resolution and assessment

    Pehrsson, Martin, Mortensen, J. H., Manon-Jensen, T., Bay-Jensen, A., Karsdal, M. A. & Davies, Michael Jonathan, 2021, In: Expert Review of Molecular Diagnostics. 21, 10, p. 1049-1064

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Ethnic differences in the prevalence and recognition of depression in a primary care population with and without type 2 diabetes

    Ali, S., Taub, N. A., Stone, M. A., Davies, Michael Jonathan, Skinner, Timothy & Khunti, K., 1 Sep 2010, Diabetologia.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

  9. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients

    Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Feb 2009, In: Free Radical Research. 43, 2, p. 117-27 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols

    Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael Jonathan, 1 Sep 2006, In: Biochemical Journal. 398, 2, p. 197-206 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage

    Pattison, D. I. & Davies, Michael Jonathan, 4 Jul 2006, In: Biochemistry. 45, 26, p. 8152-62 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque

    Fu, S., Davies, Michael Jonathan, Stocker, R. & Dean, R. T., 1 Aug 1998, In: Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins

    Zeng, J. & Davies, Michael Jonathan, Aug 2005, In: Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Exploring oxidative modifications of tyrosine: An update on mechanisms of formation, advances in analysis and biological consequences

    Houée-Lévin, C., Bobrowski, K., Horakova, L., Karademir, B., Schöneich, C., Davies, Michael Jonathan & Spickett, C. M., Apr 2015, In: Free Radical Research. 49, 4, p. 347-73 27 p.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Exposure of aconitase to smoking-related oxidants results in iron loss and increased iron response protein-1 activity: potential mechanisms for iron accumulation in human arterial cells

    Talib, J. & Davies, Michael Jonathan, 2016, In: Journal of Biological Inorganic Chemistry. 21, 3, p. 305-317 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function: [Meeting Abstract]

    Degendorfer, G., Lorentzen, Lasse Gøbel, Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Haegglund, P., Malle, E., Wise, S. & Davies, Michael Jonathan, 2018, In: Free Radical Biology and Medicine. 120, S1, p. S102-S103 P-192 .

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  17. Published

    Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function

    Degendorfer, G., Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Hägglund, Per Mårten, Malle, E., Wise, S. G. & Davies, Michael Jonathan, 1 Feb 2018, In: Free Radical Biology & Medicine. 115, S1, p. 202-214 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    FIBROSIS IS NOT JUST FIBROSIS - TGF-B AND PDGF INDUCE DIFFERENT EXTRACELLULAR MATRIX PROFILE: A MODEL OF DERMAL FIBROBLASTS WHICH MIMICS SYSTEMIC SCLEROSIS POTENTIAL FOR EVALUATION OF ANTI-FIBROTIC COMPOUNDS WITH TRANSLATIONAL BIOMARKERS [Meeting Abstract}

    Juhl, P., Bomdesen, S., Bay-Jensen, A., Karsdal, M., Davies, Michael Jonathan & Siebuhr, A. S., 2019, In: Annals of the Rheumatic Diseases. 78, S2, p. 448-449 THU0335.

    Research output: Contribution to journal › Conference abstract in journal › Research

  19. Published

    Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion

    Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael Jonathan & López-Alarcón, C., 2020, In: RSC Advances. 10, 43, p. 25786-25800 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Formation and detection of oxidant-generated tryptophan dimers in peptides and proteins

    Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael Jonathan, Dec 2017, In: Free Radical Biology & Medicine. 113, p. 132-142 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract

    Garner, B., Davies, Michael Jonathan & Truscott, R. J., Jan 2000, In: Experimental Eye Research. 70, 1, p. 81-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Formation of long-lived radicals on proteins by radical transfer from heme enzymes--a common process?

    Ostdal, H., Andersen, H. J. & Davies, Michael Jonathan, 1 Feb 1999, In: Archives of Biochemistry and Biophysics. 362, 1, p. 105-12 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Formation of protein cross-links by singlet oxygen-mediated disulfide oxidation

    Jiang, S., Carroll, L., Mariotti, M., Hägglund, Per Mårten & Davies, Michael Jonathan, 2021, In: Redox Biology. 41, 16 p., 101874.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Fragmentation of extracellular matrix by hypochlorous acid

    Woods, A. A. & Davies, Michael Jonathan, 15 Nov 2003, In: Biochemical Journal. 376, Pt 1, p. 219-27 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Free Radical Research origins

    Davies, Michael Jonathan, Jan 2012, In: Free Radical Research. 46, 1, p. 1

    Research output: Contribution to journal › Journal article › Research

  26. Published

    Generation and propagation of radical reactions on proteins

    Hawkins, C. L. & Davies, Michael Jonathan, 2 Apr 2001, In: B B A - Reviews on Cancer. 1504, 2-3, p. 196-219 24 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Generation of Aggregates of α-Lactalbumin by UV-B Light Exposure

    Zhao, Z., Engholm-Keller, Kasper, Poojary, Mahesha Manjunatha, Boelt, S. G., Rogowska-Wrzesinska, A., Skibsted, Leif Horsfelt, Davies, Michael Jonathan & Lund, Marianne N., 2020, In: Journal of Agricultural and Food Chemistry. 68, 24, p. 6701-6714 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction

    Galougahi, K. K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N. A. S., Davies, Michael Jonathan, Hawkins, Clare Louise, Rasmussen, H. H. & Figtree, G. A., 2014, In: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 2, p. e000731

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles

    Knott, H. M., Brown, B. E., Davies, Michael Jonathan & Dean, R. T., Sep 2003, In: European Journal of Biochemistry. 270, 17, p. 3572-82 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages

    Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael Jonathan, Mar 2007, In: F E B S Journal. 274, 6, p. 1530-41 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells

    Brown, Benjamin James, Dean, R. T. & Davies, Michael Jonathan, Feb 2005, In: Diabetologia. 48, 2, p. 361-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation

    Kennett, E. C. & Davies, Michael Jonathan, 15 Aug 2009, In: Free Radical Biology & Medicine. 47, 4, p. 389-400 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Guanine-specific DNA damage induced by gamma-irradiated histone

    Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael Jonathan & Kawanishi, S., 15 Jun 2005, In: Biochemical Journal. 388, Pt 3, p. 813-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives

    Rees, M. D. & Davies, Michael Jonathan, 8 Mar 2006, In: Journal of the American Chemical Society. 128, 9, p. 3085-97 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    High concentrations of casein proteins exacerbate radical chain reactions and increase the extent of oxidative damage

    Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael Jonathan, 2021, In: Food Hydrocolloids. 121, 16 p., 107060.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction

    Nedoboy, P. E., Morgan, P. E., Mocatta, T. J., Richards, A. M., Winterbourn, C. C. & Davies, Michael Jonathan, Oct 2014, In: Free Radical Research. 48, 10, p. 1256-66 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase

    Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2011, In: Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine

    Talib, J., Pattison, D. I., Harmer, J. A., Celermajer, D. S. & Davies, Michael Jonathan, 1 Jul 2012, In: Free Radical Biology & Medicine. 53, 1, p. 20-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA

    Luxford, C., Morin, B., Dean, R. T. & Davies, Michael Jonathan, 15 Nov 1999, In: Biochemical Journal. 344 Pt 1, p. 125-34 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Hypobromous acid and bromamine production by neutrophils and modulation by superoxide

    Chapman, A. L. P., Skaff, O., Senthilmohan, R., Kettle, A. J. & Davies, Michael Jonathan, 1 Feb 2009, In: Biochemical Journal. 417, 3, p. 773-81 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 175-84 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis

    Hawkins, C. L., Brown, Benjamin James & Davies, Michael Jonathan, 15 Nov 2001, In: Archives of Biochemistry and Biophysics. 395, 2, p. 137-45 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals

    Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2002, In: Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals

    Hawkins, C. L. & Davies, Michael Jonathan, Aug 2001, In: Chemical Research in Toxicology. 14, 8, p. 1071-81 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation

    Hawkins, C. L. & Davies, Michael Jonathan, 15 Jun 1998, In: Biochemical Journal. 332 ( Pt 3), p. 617-25 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Hypochlorite-induced damage to red blood cells: evidence for the formation of nitrogen-centred radicals

    Hawkins, C. L. & Davies, Michael Jonathan, 2000, In: Redox Report (Online). 5, 1, p. 57-9 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Hypochlorite-induced oxidation of amino acids, peptides and proteins

    Hawkins, C. L., Pattison, D. I. & Davies, Michael Jonathan, Dec 2003, In: Amino Acids. 25, 3-4, p. 259-74 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation

    Hawkins, C. L. & Davies, Michael Jonathan, 1 Jun 1999, In: Biochemical Journal. 340 ( Pt 2), p. 539-48 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates

    Davies, Michael Jonathan & Hawkins, C. L., Dec 2000, In: Free Radical Research. 33, 6, p. 719-29 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation

    Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 12 Nov 2003, In: Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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