Michael Jonathan Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3, 2200 København N.
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Effectiveness of a diabetes education and self management programme (DESMOND) for people with newly diagnosed type 2 diabetes mellitus: Three year follow-up of a cluster randomised controlled trial in primary care
Khunti, K., Gray, L. J., Skinner, Timothy, Carey, M. E., Realf, K., Dallosso, H., Fisher, H., Campbell, M., Heller, S. & Davies, Michael Jonathan, 9 Jun 2012, In: BMJ (Online). 344, 7860, e2333.Research output: Contribution to journal › Journal article › Research › peer-review
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Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial
Davies, Michael Jonathan, Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In: BMJ. 336, 7642, p. 491-495 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models
Chen, Z., Kondrashina, A., Greco, I., Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael Jonathan, 2019, In: Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of a novel selenium substituted-sugar (1,4-anhydro-4-seleno-D-talitol, SeTal) on human coronary artery cell lines and mouse aortic rings
Zacharias, T., Flouda, K., Jepps, Thomas Andrew Qvistgaard, Gammelgaard, Bente, Schiesser, C. H. & Davies, Michael Jonathan, 2020, In: Biochemical Pharmacology. 173, 14 p., 113631.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice: [Meeting Abstract]
Zacharias, T., Flouda, K., Jepps, T., Christoffersen, Christina, Pedersen, T., Gammelgaard, Bente, Schiesser, C. & Davies, Michael Jonathan, 20 May 2018, In: Free Radical Biology & Medicine. 120, S1, p. S68-S68 P-79.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Endothelial nitric oxide synthase plays a protective role in endothelial cells and cardiomyocytes against myocardial infarction
Gentile, C., Kesteven, S., Wu, J., Davies, Michael Jonathan, Bursill, C., Feneley, M. & Figtree, G., 2020, In: Journal of Molecular and Cellular Cardiology. 140, p. 31-31Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Enzymatic cross-linking of collagens in organ fibrosis - resolution and assessment
Pehrsson, Martin, Mortensen, J. H., Manon-Jensen, T., Bay-Jensen, A., Karsdal, M. A. & Davies, Michael Jonathan, 2021, In: Expert Review of Molecular Diagnostics. 21, 10, p. 1049-1064Research output: Contribution to journal › Review › Research › peer-review
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Ethnic differences in the prevalence and recognition of depression in a primary care population with and without type 2 diabetes
Ali, S., Taub, N. A., Stone, M. A., Davies, Michael Jonathan, Skinner, Timothy & Khunti, K., 1 Sep 2010, Diabetologia.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients
Morgan, P. E., Sturgess, A. D. & Davies, Michael Jonathan, Feb 2009, In: Free Radical Research. 43, 2, p. 117-27 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols
Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael Jonathan, 1 Sep 2006, In: Biochemical Journal. 398, 2, p. 197-206 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage
Pattison, D. I. & Davies, Michael Jonathan, 4 Jul 2006, In: Biochemistry. 45, 26, p. 8152-62 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque
Fu, S., Davies, Michael Jonathan, Stocker, R. & Dean, R. T., 1 Aug 1998, In: Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins
Zeng, J. & Davies, Michael Jonathan, Aug 2005, In: Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exploring oxidative modifications of tyrosine: An update on mechanisms of formation, advances in analysis and biological consequences
Houée-Lévin, C., Bobrowski, K., Horakova, L., Karademir, B., Schöneich, C., Davies, Michael Jonathan & Spickett, C. M., Apr 2015, In: Free Radical Research. 49, 4, p. 347-73 27 p.Research output: Contribution to journal › Review › Research › peer-review
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Exposure of aconitase to smoking-related oxidants results in iron loss and increased iron response protein-1 activity: potential mechanisms for iron accumulation in human arterial cells
Talib, J. & Davies, Michael Jonathan, 2016, In: Journal of Biological Inorganic Chemistry. 21, 3, p. 305-317 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function: [Meeting Abstract]
Degendorfer, G., Lorentzen, Lasse Gøbel, Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Haegglund, P., Malle, E., Wise, S. & Davies, Michael Jonathan, 2018, In: Free Radical Biology and Medicine. 120, S1, p. S102-S103 P-192 .Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Exposure of tropoelastin to peroxynitrous acid gives high yields of nitrated tyrosine residues, di-tyrosine cross-links and altered protein structure and function
Degendorfer, G., Chuang, Christine, Mariotti, M., Hammer, A., Hoefler, G., Hägglund, Per Mårten, Malle, E., Wise, S. G. & Davies, Michael Jonathan, 1 Feb 2018, In: Free Radical Biology & Medicine. 115, S1, p. 202-214 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FIBROSIS IS NOT JUST FIBROSIS - TGF-B AND PDGF INDUCE DIFFERENT EXTRACELLULAR MATRIX PROFILE: A MODEL OF DERMAL FIBROBLASTS WHICH MIMICS SYSTEMIC SCLEROSIS POTENTIAL FOR EVALUATION OF ANTI-FIBROTIC COMPOUNDS WITH TRANSLATIONAL BIOMARKERS [Meeting Abstract}
Juhl, P., Bomdesen, S., Bay-Jensen, A., Karsdal, M., Davies, Michael Jonathan & Siebuhr, A. S., 2019, In: Annals of the Rheumatic Diseases. 78, S2, p. 448-449 THU0335.Research output: Contribution to journal › Conference abstract in journal › Research
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Formation and characterization of crosslinks, including Tyr-Trp species, on one electron oxidation of free Tyr and Trp residues by carbonate radical anion
Figueroa, J. D., Zárate, A. M., Fuentes Lemus, Eduardo, Davies, Michael Jonathan & López-Alarcón, C., 2020, In: RSC Advances. 10, 43, p. 25786-25800 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formation and detection of oxidant-generated tryptophan dimers in peptides and proteins
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael Jonathan, Dec 2017, In: Free Radical Biology & Medicine. 113, p. 132-142 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract
Garner, B., Davies, Michael Jonathan & Truscott, R. J., Jan 2000, In: Experimental Eye Research. 70, 1, p. 81-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formation of long-lived radicals on proteins by radical transfer from heme enzymes--a common process?
Ostdal, H., Andersen, H. J. & Davies, Michael Jonathan, 1 Feb 1999, In: Archives of Biochemistry and Biophysics. 362, 1, p. 105-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formation of protein cross-links by singlet oxygen-mediated disulfide oxidation
Jiang, S., Carroll, L., Mariotti, M., Hägglund, Per Mårten & Davies, Michael Jonathan, 2021, In: Redox Biology. 41, 16 p., 101874.Research output: Contribution to journal › Journal article › Research › peer-review
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Fragmentation of extracellular matrix by hypochlorous acid
Woods, A. A. & Davies, Michael Jonathan, 15 Nov 2003, In: Biochemical Journal. 376, Pt 1, p. 219-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Free Radical Research origins
Davies, Michael Jonathan, Jan 2012, In: Free Radical Research. 46, 1, p. 1Research output: Contribution to journal › Journal article › Research
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Generation and propagation of radical reactions on proteins
Hawkins, C. L. & Davies, Michael Jonathan, 2 Apr 2001, In: B B A - Reviews on Cancer. 1504, 2-3, p. 196-219 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Generation of Aggregates of α-Lactalbumin by UV-B Light Exposure
Zhao, Z., Engholm-Keller, Kasper, Poojary, Mahesha Manjunatha, Boelt, S. G., Rogowska-Wrzesinska, A., Skibsted, Leif Horsfelt, Davies, Michael Jonathan & Lund, Marianne N., 2020, In: Journal of Agricultural and Food Chemistry. 68, 24, p. 6701-6714 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction
Galougahi, K. K., Liu, C., Gentile, C., Kok, C., Nunez, A., Garcia, A., Fry, N. A. S., Davies, Michael Jonathan, Hawkins, Clare Louise, Rasmussen, H. H. & Figtree, G. A., 2014, In: American Heart Association. Journal. Cardiovascular and Cerebrovascular Disease. 3, 2, p. e000731Research output: Contribution to journal › Journal article › Research › peer-review
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Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles
Knott, H. M., Brown, B. E., Davies, Michael Jonathan & Dean, R. T., Sep 2003, In: European Journal of Biochemistry. 270, 17, p. 3572-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages
Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael Jonathan, Mar 2007, In: F E B S Journal. 274, 6, p. 1530-41 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells
Brown, Benjamin James, Dean, R. T. & Davies, Michael Jonathan, Feb 2005, In: Diabetologia. 48, 2, p. 361-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation
Kennett, E. C. & Davies, Michael Jonathan, 15 Aug 2009, In: Free Radical Biology & Medicine. 47, 4, p. 389-400 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Guanine-specific DNA damage induced by gamma-irradiated histone
Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael Jonathan & Kawanishi, S., 15 Jun 2005, In: Biochemical Journal. 388, Pt 3, p. 813-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives
Rees, M. D. & Davies, Michael Jonathan, 8 Mar 2006, In: Journal of the American Chemical Society. 128, 9, p. 3085-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High concentrations of casein proteins exacerbate radical chain reactions and increase the extent of oxidative damage
Fuentes Lemus, Eduardo, Jiang, S., Hägglund, Per Mårten & Davies, Michael Jonathan, 2021, In: Food Hydrocolloids. 121, 16 p., 107060.Research output: Contribution to journal › Journal article › Research › peer-review
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High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction
Nedoboy, P. E., Morgan, P. E., Mocatta, T. J., Richards, A. M., Winterbourn, C. C. & Davies, Michael Jonathan, Oct 2014, In: Free Radical Research. 48, 10, p. 1256-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase
Morgan, P. E., Pattison, D. I., Talib, J., Summers, F. A., Harmer, J. A., Celermajer, D. S., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Nov 2011, In: Free Radical Biology & Medicine. 51, 9, p. 1815-22 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
High plasma thiocyanate levels modulate protein damage induced by myeloperoxidase and perturb measurement of 3-chlorotyrosine
Talib, J., Pattison, D. I., Harmer, J. A., Celermajer, D. S. & Davies, Michael Jonathan, 1 Jul 2012, In: Free Radical Biology & Medicine. 53, 1, p. 20-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA
Luxford, C., Morin, B., Dean, R. T. & Davies, Michael Jonathan, 15 Nov 1999, In: Biochemical Journal. 344 Pt 1, p. 125-34 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypobromous acid and bromamine production by neutrophils and modulation by superoxide
Chapman, A. L. P., Skaff, O., Senthilmohan, R., Kettle, A. J. & Davies, Michael Jonathan, 1 Feb 2009, In: Biochemical Journal. 417, 3, p. 773-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates
Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis
Hawkins, C. L., Brown, Benjamin James & Davies, Michael Jonathan, 15 Nov 2001, In: Archives of Biochemistry and Biophysics. 395, 2, p. 137-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals
Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2002, In: Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals
Hawkins, C. L. & Davies, Michael Jonathan, Aug 2001, In: Chemical Research in Toxicology. 14, 8, p. 1071-81 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation
Hawkins, C. L. & Davies, Michael Jonathan, 15 Jun 1998, In: Biochemical Journal. 332 ( Pt 3), p. 617-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced damage to red blood cells: evidence for the formation of nitrogen-centred radicals
Hawkins, C. L. & Davies, Michael Jonathan, 2000, In: Redox Report (Online). 5, 1, p. 57-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced oxidation of amino acids, peptides and proteins
Hawkins, C. L., Pattison, D. I. & Davies, Michael Jonathan, Dec 2003, In: Amino Acids. 25, 3-4, p. 259-74 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation
Hawkins, C. L. & Davies, Michael Jonathan, 1 Jun 1999, In: Biochemical Journal. 340 ( Pt 2), p. 539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates
Davies, Michael Jonathan & Hawkins, C. L., Dec 2000, In: Free Radical Research. 33, 6, p. 719-29 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation
Rees, M. D., Hawkins, Clare Louise & Davies, Michael Jonathan, 12 Nov 2003, In: Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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