Thomas Jespersen

Thomas Jespersen

Professor

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    ORCID: 0000-0001-6575-360X

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    1. Published

      3D-electroanatomical mapping of the left atrium and catheter-based pulmonary vein isolation in pigs: A practical guide

      Hertel, Julie Norup, Jerltorp, K., Hansen, M. E. H., Isaksen, Jonas L., Sattler, Stefan M, Linz, Benedikt Maximilian, Chaldoupi, S. M., Jespersen, Thomas, Saljic, Arnela, Gang, Uffe Jakob Ortved, Manninger, M. & Dr Linz, Dominik Karl, 2023, In: Frontiers in Cardiovascular Medicine. 10, 8 p., 1139364.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      5-HT1A receptors modulate small-conductance Ca2+-activated K+ channels.

      Grunnet, Morten, Jespersen, Thomas & Perrier, J., 2004, In: Journal of Neuroscience Research. 78, 6, p. 845-54 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      A Multiple Kernel Learning Framework to Investigate the Relationship Between Ventricular Fibrillation and First Myocardial Infarction

      Marciniak, M., Arevalo, H., Tfelt-Hansen, Jacob, Ahtarovski, K. A., Jespersen, Thomas, Jabbari, R., Glinge, C., Vejlstrup, N., Engstrøm, Thomas, Maleckar, M. M. & McLeod, K., 1 Jan 2017, Functional Imaging and Modelling of the Heart: 9th International Conference, FIMH 2017, Toronto, ON, Canada, June 11-13, 2017, Proceedings. Springer, p. 161-171 11 p. (Lecture Notes in Computer Science, Vol. 10263 LNCS).

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

    4. Published

      A Novel Nonsense Variant in Nav1.5 Cofactor MOG1 Eliminates Its Sodium Current Increasing Effect and May Increase the Risk of Arrhythmias

      Olesen, M. S., Jensen, N. F., Holst, A. G., Nielsen, J. B., Tfelt-Hansen, Jacob, Jespersen, Thomas, Sajadieh, Ahmad, Haunsø, Stig, Lund, J. T., Callø, Kirstine, Schmitt, Nicole & Svendsen, Jesper Hastrup, 26 May 2011, In: Canadian Journal of Cardiology. 27, 4, p. 523.e17-23

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease

      Holst, A. G., Callø, Kirstine, Jespersen, Thomas, Cedergreen, P., Winkel, B. G., Jensen, H. K., Leren, T. P., Haunso, S., Svendsen, Jesper Hastrup & Tfelt-Hansen, J., 2009, In: Case Reports in Medicine. 2009, p. 963645

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      A Novel SCN5A Variant Associated with Abnormal Repolarization, Atrial Fibrillation, and Reversible Cardiomyopathy

      Boddum, K., Saljic, Arnela, Jespersen, Thomas & Christensen, A. H., 2018, In: Cardiology. 140, 1, p. 8-13

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      A novel approach for obtaining 12-lead electrocardiograms in horses

      Hesselkilde, E. M., Isaksen, Jonas L., Petersen, B. V., Carstensen, Helena, Jespersen, Thomas, Pehrson, S., Kanters, Jørgen K. & Buhl, Rikke, 2021, In: Journal of Veterinary Internal Medicine. 35, 1, p. 521-531

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

      Andersen, M. N., Krzystanek, K., Petersen, F., Bomholtz, Sofia Hammami, Olesen, Søren-Peter, Abriel, H., Jespersen, Thomas & Rasmussen, Hanne Borger, 8 Nov 2013, In: The Journal of Biological Chemistry. 288, 52, p. 36841-54 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      AMP-activated protein kinase downregulates Kv7.1 cell surface expression

      Andersen, M. N., Krzystanek, K., Jespersen, Thomas, Olesen, Søren-Peter & Rasmussen, Hanne Borger, 2012, In: Traffic. 13, 1, p. 143-56 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352.

      Dupuis, D. S., Schrøder, R. L., Jespersen, Thomas, Christensen, J. K., Christophersen, P., Jensen, B. S. & Olesen, Søren-Peter, 2002, In: European Journal of Pharmacology. 437, 3, p. 129-37 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury

      Bentzen, Bo Hjorth, Osadchii, O., Jespersen, Thomas, Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2009, In: Pflügers Archiv: European Journal of Physiology. 457, 5, p. 979-88 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Adiposity-associated atrial fibrillation: molecular determinants, mechanisms, and clinical significance

      Gawalko, M., Saljic, Arnela, Li, N., Abu-Taha, I., Jespersen, Thomas, Dr Linz, Dominik Karl, Nattel, S., Heijman, J., Fender, A. & Dobrev, D., 2023, In: Cardiovascular Research. 119, 3, p. 614–630 17 p.

      Research output: Contribution to journal › Review › Research › peer-review

    13. Published

      Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V

      Lubberding, Anniek Frederike, Zhang, J., Lundh, M., Nielsen, Thomas Svava, Søndergaard, M. S., Villadsen, M., Skovhøj, E. Z., Boer, G. A., Hansen, J. B., Thomsen, Morten Bækgaard, Treebak, Jonas Thue, Holst, Jens Juul, Kanters, Jørgen K., Mandrup-Poulsen, Thomas, Jespersen, Thomas, Emanuelli, Brice & Torekov, Signe Sørensen, 2021, In: Scientific Reports. 11, 1, 14 p., 12253.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Amiodarone Treatment in the Early Phase of Acute Myocardial Infarction Protects Against Ventricular Fibrillation in a Porcine Model

      Sattler, Stefan M, Lubberding, Anniek Frederike, Skibsbye, L., Jabbari, R., Wakili, R., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2019, In: Journal of Cardiovascular Translational Research. 12, 4, p. 321-330

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      An ERG channel inhibitor from the scorpion Buthus eupeus

      Korolkova, Y. V., Kozlov, S. A., Lipkin, A. V., Pluzhnikov, K. A., Hadley, J. K., Filippov, A. K., Brown, D. A., Pedersen, K. A., Strøbaek, D., Jespersen, Thomas, Olesen, Søren-Peter, Jensen Skanning, B. & Grishin, E. V., 30 Mar 2001, In: Journal of Biological Chemistry. 276, 13, p. 9868-76 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo

      Duch, M. R., Carrasco, M. L., Jespersen, T., Aagaard, L., Pedersen, F. S. & Jespersen, Thomas, 1 Jan 2004, In: Nucleic Acids Symposium Series. 32, 6, p. 2039-48 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome.

      Petitprez, S., Jespersen, Thomas, Pruvot, E., Keller, D. I., Corbaz, C., Schläpfer, J., Abriel, H. & Kucera, J. P., 2008, In: Cardiovascular Research. 78, 3, p. 494-504 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Analysis and exploitation of murine leukemia virus cis- and trans-elements using novel transduction systems

      Jespersen, Thomas, 3 Mar 1999

      Research output: Book/Report › Ph.D. thesis › Research

    19. Published

      Anti-arrhythmic investigations in large animal models of atrial fibrillation

      Saljic, Arnela, Jespersen, Thomas & Buhl, Rikke, 2022, In: British Journal of Pharmacology. 179, 5, p. 838-858

      Research output: Contribution to journal › Review › Research › peer-review

    20. Published

      Antiarrhythmic Effects of Combining Dofetilide and Ranolazine in a Model of Acutely Induced Atrial Fibrillation in Horses

      Carstensen, Helena, Kjær, L., Haugaard, M. M., Flethøj, M., Hesselkilde, E. Z., Kanters, Jørgen K., Pehrson, S., Buhl, Rikke & Jespersen, Thomas, Jan 2018, In: Journal of Cardiovascular Pharmacology. 71, 1, p. 26-35 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

      Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses

      Haugaard, M. M., Pehrson, S., Carstensen, Helena, Madsen, M. F., Hesselkilde, E. Z., Præstegaard, K. F., Diness, J. G., Grunnet, M., Jespersen, Thomas & Buhl, Rikke, 2015, In: Journal of Veterinary Internal Medicine. 29, 1, p. 339-347 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Antiarrhythmic effect of IKr activation in a cellular model of LQT3

      Diness, Jonas Goldin, Hansen, R. S., Nissen, J. D., Jespersen, Thomas & Grunnet, Morten, 2008, In: Heart Rhythm. 6, 1, p. 100-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Antiarrhythmic effect of either negative modulation or blockade of small conductance Ca2+ activated K+ channels on ventricular fibrillation in guinea pig Langendorff perfused heart

      Diness, J. G., Kirchhoff, J. E., Sheykhzade, Majid, Jespersen, Thomas & Grunnet, M., 8 May 2015, In: Journal of Cardiovascular Pharmacology. 66, 3, p. 294–299 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation

      Kirchhoff, J. E., Diness, Jonas Goldin, Abildgaard, L., Sheykhzade, Majid, Grunnet, Morten & Jespersen, Thomas, 8 Oct 2016, In: Pfluegers Archiv. 468, 11, p. 1853–1863 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Arrhythmia development during inhibition of small-conductance calcium-activated potassium channels in acute myocardial infarction in a porcine model

      Lubberding, Anniek Frederike, Sattler, Stefan M, Grunnet, Morten, Sørensen, U. S., Tfelt-Hansen, Jacob & Jespersen, Thomas, Oct 2019, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 21, 10, p. 1584–1593

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Arrhythmogenic mechanisms of acute obstructive respiratory events in a porcine model of drug-induced Long-QT

      Linz, Benedikt Maximilian, Sattler, Stefan M, Flethoj, M., Høtbjerg Hansen, M. E., Hesselkilde, E. M., Saljic, Arnela, Wirth, K., Dr Linz, Dominik Karl, Tfelt-Hansen, Jacob & Jespersen, Thomas, 2021, In: Heart Rhythm. 18, 8, p. 1384-1391

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Arvelige hjertesygdomme forårsaget af natriumkanalmutationer

      Tfelt-Hansen, J., Olesen, Søren-Peter, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2009, In: Ugeskrift for læger. 171, 15, p. 1261-5 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Associations between thyroid-stimulating hormone, blood pressure and adiponectin are attenuated in children and adolescents with overweight or obesity

      Drivsholm, A., Lund, Morten Asp Vonsild, Hedley, P. L., Jespersen, Thomas, Christiansen, M., Hansen, Torben & Holm, Jens-Christian, 2019, In: Journal of Pediatric Endocrinology and Metabolism. 32, 12, p. 1351-1358

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Atrieflimmer og elektrofysiologi hos heste

      Haugaard, M. M., Buhl, Rikke & Jespersen, Thomas, 2011, In: Dansk Veterinaertidsskrift. 12, p. 28-31 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure

      Nissen, J. D., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Diness, Jonas Goldin, Diness, T. G., Jespersen, Thomas & Grunnet, Morten, 2012, In: Journal of Cardiovascular Pharmacology. 59, 2, p. 142-150 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif.

      Jespersen, Thomas, Rasmussen, Hanne Borger, Grunnet, Morten, Jensen, H. S., Angelo, K., Dupuis, D. S., Vogel, L. K., Jorgensen, N. K., Klærke, Dan Arne & Olesen, Søren-Peter, 2004, In: Journal of Cell Science. 117, Pt 19, p. 4517-26 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Biophysical characterization of KV3.1 potassium channel activating compounds

      Taskin, B., von Schoubye, N. L., Sheykhzade, Majid, Bastlund, J. F., Grunnet, M. & Jespersen, Thomas, 5 Jul 2015, In: European Journal of Pharmacology. 758, p. 164-170 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms

      Tang, C., Skibsbye, L., Yuan, L., Bentzen, Bo Hjorth & Jespersen, Thomas, Oct 2015, In: General Physiology and Biophysics. 34, 4, p. 383-92 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Brugada syndrome unmasked by accidental inhalation of gasoline vapors.

      Kranjcec, D., Bergovec, M., Rougier, J., Raguz, M., Pavlovic, S., Jespersen, Thomas, Castella, V., Keller, D. I. & Abriel, H., 2007, In: Pacing and Clinical Electrophysiology. 30, 10, p. 1294-8 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Cardiac Arrhythmia - new considerations: The Cardiac Ion Channels

      Jespersen, Thomas, 29 Feb 2012, Cardiac Arrhythmias - new considerations. Breijo-Marquez, F. R. (ed.). Croatia: InTech, p. 45-72 29 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    37. Published

      Cardiac channelopathies and sudden infant death syndrome

      Tfelt-Hansen, J., Winkel, B. G., Grunnet, Morten & Jespersen, Thomas, 2011, In: The Cardiology. 119, 1, p. 21-33 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1.

      Jespersen, Thomas, Gavillet, B., van Bemmelen, M. X., Cordonier, S., Thomas, M. A., Staub, O. & Abriel, H., 2006, In: Biochemical and Biophysical Research Communications. 348, 4, p. 1455-62 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Cartilaginous Intrusion of the Atrioventricular Node in a Quarter Horse with a High Burden of Second-Degree AV Block and Collapse: A Case Report

      Nissen, Sarah Dalgas, Saljic, Arnela, Kjeldsen, S. T., Jespersen, Thomas, Hopster-Iversen, Charlotte & Buhl, Rikke, 2022, In: Animals. 12, 21, 2915.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Cause-specific mortality in children and young adults with diabetes mellitus: A Danish nationwide cohort study

      Svane, Jesper, Lynge, T. H., Pedersen-Bjergaard, Ulrik, Jespersen, Thomas, Gislason, Gunnar Hilmar, Risgaard, B., Winkel, B. G. & Tfelt-Hansen, Jacob, 2021, In: European Journal of Preventive Cardiology. 28, 2, p. 159-165

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Change in global longitudinal strain following acute coronary syndrome and subsequent risk of heart failure

      Ravnkilde, K., Skaarup, K. G., Grove, G. L., Modin, D., Nielsen, A. B., Falsing, M. M., Iversen, A. Z., Pedersen, S., Fritz-Hansen, T., Galatius, S., Jespersen, Thomas, Shah, A., Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2021, In: International Journal of Cardiovascular Imaging. 37, p. 3193–3202

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Characterization of cardiac repolarization in the Göttingen minipig

      Laursen, M., Olesen, Søren-Peter, Grunnet, Morten, Mow, T., Jespersen, T. & Jespersen, Thomas, 2011, In: Journal of Pharmacological and Toxicological Methods. 63, 2, p. 186-95 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.

      Larsen, A. P., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, 2008, In: Pflügers Archiv: European Journal of Physiology. 456, 6, p. 1137-48 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Characterization of two new dominant ClC-1 channel mutations associated with myotonia.

      Grunnet, Morten, Jespersen, Thomas, Colding-Jørgensen, E., Schwartz, M., Klærke, Dan Arne, Vissing, John, Olesen, Søren-Peter & Dunø, M., 2003, In: Muscle & Nerve. 28, 6, p. 722-32 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Clinical Implications of SCN10A Loss-of-Function Variants in 169 610 Exomes Representing the General Population.

      Paludan-Müller, Christian, Larsen, S., Ahlberg, G., Monfort, L. M., Andreasen, L., Svendsen, Jesper Hastrup, Jespersen, Thomas, Bundgård, Henning, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2022, In: Circulation. Genomic and precision medicine. 15, 1, p. 83-85 3 p., e003574.

      Research output: Contribution to journal › Letter › Research › peer-review

    46. Published

      Combined In-silico and Machine Learning Approaches Toward Predicting Arrhythmic Risk in Post-infarction Patients

      Maleckar, M. M., Myklebust, L., Uv, J., Florvaag, P. M., Strøm, V., Glinge, C., Jabbari, R., Vejlstrup, N., Engstrøm, Thomas, Ahtarovski, K., Jespersen, Thomas, Tfelt-Hansen, Jacob, Naumova, V. & Arevalo, H., 2021, In: Frontiers in Physiology. 12, 745349.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family

      Kanters, Jørgen K., Skibsbye, L., Hedley, P. L., Dembic, M., Liang, B., Hagen, C. M., Eschen, O., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 2015, In: Scandinavian Journal of Clinical & Laboratory Investigation. 75, 8, p. 699-709 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Common and rare variants in SCN10A modulate the risk of atrial fibrillation.

      Jabbari, J., Olesen, Morten Steen Salling, Yuan, L., Nielsen, J. B., Liang, B., Macri, V., Christophersen, I. E., Nielsen, N., Sajadieh, Ahmad, Ellinor, P. T., Grunnet, Morten, Haunsø, Stig, Holst, A. G., Svendsen, Jesper Hastrup & Jespersen, Thomas, 2015, In: Circulation: Cardiovascular Genetics. 8, 1, p. 64-73 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Comparison of hemodynamics, cardiac electrophysiology and ventricular arrhythmia in an open and a closed chest porcine model of acute myocardial infarction

      Lubberding, Anniek Frederike, Sattler, Stefan M, Flethøj, M., Tfelt-Hansen, Jacob & Jespersen, Thomas, 2020, In: American Journal of Physiology: Heart and Circulatory Physiology. 318, 2, p. H391-H400

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded from Atrial and Ventricular Cardiomyocytes.

      Callø, Kirstine, Nof, E., Jespersen, Thomas, Di Diego, J. M., Chlus, N., Olesen, Søren-Peter, Antzelevitch, C. & Cordeiro, J. M., 2011, In: Journal of Cardiovascular Electrophysiology. 22, 9, p. 1057-1066 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Decreased Heart Rate After Dapagliflozin Treatment In Gottingen Minipigs With Chronic Myocardial Infarction

      Debes, Karina Poulsdóttir, Lyhne, Mille Kronborg, Hinz, K., Sand, K. P., Rose, V. H., Flethøj, M., Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2024, In: Journal of Cardiac Failure. 30, 1, p. 267-268

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    52. Published

      Detection of atrial fibrillation with implantable loop recorders in horses

      Buhl, Rikke, Hesselkilde, E. M., Carstensen, Helena, Fenner, Merle Friederike, Jespersen, Thomas, Tfelt-Hansen, Jacob & Sattler, Stefan M, 2021, In: Equine Veterinary Journal. 53, 2, p. 397-403

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels

      Krzystanek, K., Rasmussen, Hanne Borger, Grunnet, Morten, Staub, O., Olesen, Søren-Peter, Abriel, H. & Jespersen, Thomas, 2012, In: Heart Rhythm. 9, 3, p. 440-8 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

      Axelsen, L. N., Callø, Kirstine, Braunstein, T. H., Riemann, Mads, Hofgaard, J. P., Liang, B., Jensen, C. F., Olsen, Kristine Boisen, Bartels, Emil Daniel, Baandrup, U., Jespersen, Thomas, Nielsen, L. B., von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, 14 Jul 2015, In: Cardiovascular Diabetology. 14, 14 p., 87.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Difference in allelic expression of the CLCN1 gene and the possible influence on the myotonia congenita phenotype.

      Dunø, M., Colding-Jørgensen, E., Grunnet, Morten, Jespersen, Thomas, Vissing, John & Schwartz, M., 2004, In: European Journal of Human Genetics. 12, 9, p. 738-43 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

      Callø, Kirstine, Soltysinska, E., Jespersen, Thomas, Lundby, Alicia, Antzelevitch, C., Olesen, Søren-Peter & Cordeiro, J. M., 2009, In: Journal of Molecular and Cellular Cardiology. 48, 1, p. 191-200 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Does KCNE5 play a role in long QT syndrome?

      Hofman-Bang, J., Jespersen, Thomas, Grunnet, Morten, Larsen, Lars Allan, Andersen, P. S., Kanters, Jørgen K., Kjeldsen, K. & Christiansen, M., 2004, In: Clinica Chimica Acta. 345, 1-2, p. 49-53 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Published

      Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization

      Jørgensen, S. T., Eriksen, H. N., Dausell, J., Jespersen, Thomas, Lambert, Ian Henry & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 31, 2-3, p. 366-378 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes

      Jespersen, Thomas, Grunnet, Morten, Angelo, K., Klærke, Dan Arne & Olesen, Poul, 1 Mar 2002, In: BioTechniques. 32, 3, p. 536-8, 540

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Dynein regulates Kv7.4 channel trafficking from the cell membrane

      van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      Early Systolic Lengthening in Patients With ST-Segment-Elevation Myocardial Infarction: A Novel Predictor of Cardiovascular Events

      Brainin, P., Haahr-Pedersen, S., Olsen, F. J., Holm, A. E., Fritz-Hansen, T., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2020, In: Journal of the American Heart Association. 9, 3, p. e013835

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Early systolic lengthening in patients with ST-segment elevation myocardial infarction: a novel predictor of cardiovascular events

      Brainin, P., Haahr-Pedersen, S., Olsen, F. J., Fritz-Hansen, T., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2019, In: European Heart Journal. 40, Suppl. 1, p. 718-718 1 p., 1270 .

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    63. Published

      Effect of Selective IK,ACh Inhibition by XAF-1407 in an Equine Model of Tachypacing-induced Persistent Atrial Fibrillation (AF)

      Jespersen, Thomas, Fenner, Merle Friederike & Buhl, Rikke, 2019, In: Acta Physiologica. 227, S721, p. 96-96

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    64. Published

      Effect of Selective IK,ACh Inhibition by XAF-1407 in an Equine Model of Tachypacing-induced Persistent Atrial Fibrillation (AF)

      Fenner, Merle Friederike, Carstensen, Helena, Nissen, Sarah Dalgas, Hesselkilde, E. Z., Lunddahl, C., Jensen, M. A. H., Loft-Andersen, A. V., Sattler, Stefan M, Platonov, P. G., El-Haou, S., Jackson, C., Tang, R., Kirby, R., Ford, J. W., Schotten, U., Milnes, J. T., Sørensen, U. S., Jespersen, Thomas & Buhl, Rikke, 2020, In: British Journal of Pharmacology. 177, 16, p. 3778-3794

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. Published

      Effect of flecainide on atrial fibrillatory rate in a large animal model with induced atrial fibrillation

      Hesselkilde, E. Z., Carstensen, Helena, Haugaard, M. M., Carlson, J., Pehrson, S., Jespersen, Thomas, Buhl, Rikke & Platonov, P. G., Dec 2017, In: B M C Cardiovascular Disorders. 17, 6 p., 289.

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. Published

      Effect of induced chronic atrial fibrillation on exercise performance in Standardbred trotters

      Buhl, Rikke, Carstensen, Helena, Hesselkilde, E. Z., Klein, B. Z., Hougaard, K. M., Ravn, K. B., Loft-Andersen, A. V., Fenner, Merle Friederike, Pipper, C. & Jespersen, Thomas, 2018, In: Journal of Veterinary Internal Medicine. 32, 4, p. 1410-1419 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    67. Published

      Effect of the antipsychotic drug haloperidol on arrhythmias during acute myocardial infarction in a porcine model

      Sattler, Stefan M, Lubberding, Anniek Frederike, Kristensen, C. B., Møgelvang, R., Blanche, Paul Frédéric, Fink-Jensen, Anders, Engstrøm, Thomas, Kääb, S., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2020, In: IJC Heart and Vasculature. 26, 100455.

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. Published

      Effective termination of atrial fibrillation by SK channel inhibition is associated with a sudden organization of fibrillatory conduction

      Gatta, G., Sobota, V., Citerni, C., Diness, Jonas Goldin, Sørensen, U. S., Jespersen, Thomas, Bentzen, Bo Hjorth, Zeemering, S., Kuiper, M., Verheule, S., Schotten, U. & Van Hunnik, A., 2021, In: Europace. 23, 11, p. 1847-1859 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. Published

      Effects of dofetilide and ranolazine on atrial fibrillatory rate in a horse model of acutely induced atrial fibrillation

      Carstensen, Helena, Hesselkilde, E. Z., Haugaard, M. M., Flethøj, M., Carlson, J., Pehrson, S., Jespersen, Thomas, Platonov, P. G. & Buhl, Rikke, 2019, In: Journal of Cardiovascular Electrophysiology. 30, 4, p. 596-606

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition

      Diness, Jonas Goldin, Skibsbye, L., Jespersen, Thomas, Bartels, Emil Daniel, Sørensen, U. S., Hansen, R. S. & Grunnet, Morten, 2011, In: Hypertension. 57, 6, p. 1129-35 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. Published

      Efficient non-PCR-mediated overlap extension of PCR fragments by exonuclease "end polishing"

      Jespersen, Thomas, Duch, M. R. & Pedersen, F. S., 1 Jul 1997, In: BioTechniques. 23, 1, p. 48, 50, 52

      Research output: Contribution to journal › Journal article › Research › peer-review

    72. Published

      Electrocardiographic characteristics of trained and untrained standardbred racehorses

      Nissen, Sarah Dalgas, Weis, R., Krag-Andersen, E. K., Hesselkilde, E. M., Isaksen, Jonas L., Carstensen, Helena, Kanters, Jørgen K., Dr Linz, Dominik Karl, Sanders, P., Hopster-Iversen, Charlotte, Jespersen, Thomas, Pehrson, S. & Buhl, Rikke, 2022, In: Journal of Veterinary Internal Medicine. 36, 3, p. 1119-1130

      Research output: Contribution to journal › Journal article › Research › peer-review

    73. Published

      Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts

      Hoeker, G. S., Skarsfeldt, M. A., Jespersen, Thomas & Poelzing, S., Jan 2017, In: Physiological Reports. 5, 1, 10 p., e13120.

      Research output: Contribution to journal › Journal article › Research › peer-review

    74. Published

      Enhanced Ca2+-Dependent SK-Channel Gating and Membrane Trafficking in Human Atrial Fibrillation

      Heijman, J., Zhou, X., Morotti, S., Molina, C. E., Abu-Taha, I. H., Tekook, M., Jespersen, Thomas, Zhang, Y., Dobrev, S., Milting, H., Gummert, J., Karck, M., Kamler, M., El-Armouche, A., Saljic, Arnela, Grandi, E., Nattel, S. & Dobrev, D., 2023, In: Circulation Research. 132, 9, p. E116-E133

      Research output: Contribution to journal › Journal article › Research › peer-review

    75. Published

      Expression of heterologous genes from an IRES translational cassette in replication competent murine leukemia virus vectors

      Jespersen, Thomas, Duch, M. R., Carrasco, M. L., Warming, S. & Pedersen, F. S., 1 Nov 1999, In: Gene. 239, 2, p. 227-35 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    76. Published

      First catheter-based high-density endocardial 3D electroanatomical mapping of the right atrium in standing horses

      Hesselkilde, E., Dr Linz, Dominik Karl, Saljic, Arnela, Carstensen, Helena, Kutieleh, R., Jespersen, Thomas, Sanders, P. & Buhl, Rikke, 2021, In: Equine Veterinary Journal. 53, 4, p. 186-193

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Published

      Flecainide provocation reveals concealed brugada syndrome in a long QT syndrome family with a novel L1786Q mutation in SCN5A. SCN5A mutations associated with overlap phenotype of long QT syndrome type 3 and Brugada syndrome.

      Kanters, Jørgen K., Yuan, L., Hedley, P. L., Stoevring, B., Jons, C., Bloch Thomsen, P. E., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 6 Mar 2014, In: Circulation Journal. 78, 5, p. 1136-43 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    78. Published

      From CMR Image to Patient-Specific Simulation and Population-Based Analysis: Tutorial for an Openly Available Image-Processing Pipeline

      Marciniak, M., Arevalo, H., Tfelt-Hansen, Jacob, Jespersen, Thomas, Jabbari, R., Glinge, C., Ahtarovski, K. A., Vejlstrup, N., Engstrøm, Thomas, Maleckar, M. M. & McLeod, K., 1 Jan 2017, Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges - 7th International Workshop, STACOM 2016 Held in Conjunction with MICCAI 2016, Revised Selected Papers. Springer, p. 106-117 12 p. (Lecture Notes in Computer Science, Vol. 10124 LNCS).

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

    79. Published

      Functional testing of a bicistronic retroviral vector for intracellular peptide production

      Duch, M. R., Tolstrup, A., Dalum, I., Jespersen, Thomas, Mouritsen, S. & Pedersen, F. S., 1 Jun 1999, In: BioTechniques. 26, 6, p. 1032-4, 1036

      Research output: Contribution to journal › Journal article › Research › peer-review

    80. Published

      Functionally Selective AT(1) Receptor Activation Reduces Ischemia Reperfusion Injury

      Hostrup, A., Christensen, G. L., Bentzen, Bo Hjorth, Liang, B., Aplin, M., Grunnet, Morten, Hansen, J. L. & Jespersen, Thomas, 30 Jul 2012, In: Cellular Physiology and Biochemistry. 30, 3, p. 642-652 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. Published

      G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

      Liang, B., Nissen, J. D., Laursen, M., Wang, X., Skibsbye, L., Hearing, M. C., Andersen, M. N., Rasmussen, Hanne Borger, Wickman, K., Grunnet, Morten, Olesen, Søren-Peter & Jespersen, Thomas, 1 Jan 2014, In: Cardiovascular Research. 101, 1, p. 175-84 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    82. Published

      GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology

      Wang, X., Liang, B., Skibsbye, L., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, Aug 2013, In: Journal of Cardiovascular Pharmacology. 62, 2, p. 192-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. Published

      Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications

      Gawalko, M., Agbaedeng, T. A., Saljic, Arnela, Mueller, D. N., Wilck, N., Schnabel, R., Penders, J., Rienstra, M., van Gelder, I., Jespersen, Thomas, Schotten, U., Crijns, H. J. G. M., Kalman, J. M., Sanders, P., Nattel, S., Dobrev, D. & Dr Linz, Dominik Karl, 2022, In: Cardiovascular Research. 118, 11, p. 2415–2427

      Research output: Contribution to journal › Review › Research › peer-review

    84. Published

      High Prevalence of Long QT Syndrome Associated SCN5A Variants in Patients with Early-Onset Lone Atrial Fibrillation

      Olesen, M. S., Yuan, L., Liang, B., Holst, A. G., Nielsen, N., Nielsen, J. B., Hedley, P. L., Christiansen, M., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole, Jespersen, Thomas & Svendsen, Jesper Hastrup, 2012, In: Circulation: Cardiovascular Genetics. 5, 4, p. 450-459 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    85. Published

      Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome

      Yang, Y., Yang, Y., Liang, B., Liu, J., Li, J., Grunnet, M., Olesen, S-P., Rasmussen, H. B., Ellinor, P. T., Gao, L., Lin, X., Li, L., Wang, L., Xiao, J., Liu, Y., Liu, Y., Zhang, S., Liang, D., Peng, L., Jespersen, T. & 1 others, Chen, Y., 2010, In: American Journal of Human Genetics. 86, 6, p. 872-80 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    86. Published

      Impact of arrhythmogenic calmodulin variants on small conductance Ca2+-activated K+ (SK3) channels

      Saljic, Arnela, Muthukumarasamy, K. M., la Cour, J. M., Boddum, K., Grunnet, Morten, Berchtold, Martin Werner & Jespersen, Thomas, 2019, In: Physiological Reports. 7, 19, 13 p., e14210.

      Research output: Contribution to journal › Journal article › Research › peer-review

    87. Published

      Implantable loop recorders can detect paroxysmal atrial fibrillation in Standardbred racehorses with intermittent poor performance

      Buhl, Rikke, Nissen, Sarah Dalgas, Winther, M. L. K., Poulsen, S. K., Hopster-Iversen, Charlotte, Jespersen, Thomas, Sanders, P., Carstensen, Helena & Hesselkilde, E. M., 2021, In: Equine Veterinary Journal. 53, 5, p. 955-963

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. Published

      Implantable loop recorders for arrhythmia detection - a new promising diagnostic tool for longterm arrhythmia monitoring

      Hesselkilde, E. Z., Carsten, H., Fenner, Merle Friederike, Jespersen, Thomas, T-felt, J., Sattler, Stefan M & Buhl, Rikke, 2019, In: Acta Physiologica. 227, S721, p. 93-93 35.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    89. Published

      In vivo knockdown of SK3 channels using antisense oligonucleotides protects against atrial fibrillation in rats

      Saljic, Arnela, Soattin, Luca, Trachsel, D. S., Boddum, K. & Jespersen, Thomas, Oct 2020, In: Journal of Molecular and Cellular Cardiology. 147, p. 18-26

      Research output: Contribution to journal › Journal article › Research › peer-review

    90. Published

      Increased fibroblast accumulation in the equine heart following persistent atrial fibrillation

      Saljic, Arnela, Fenner, Merle Friederike, Winters, J., Flethøj, M., Eggert Eggertsen, C., Carstensen, Helena, Nissen, Sarah Dalgas, Melis Hesselkilde, E., van Hunnik, A., Schotten, U., Sørensen, U., Jespersen, Thomas, Verheule, S. & Buhl, Rikke, 2021, In: IJC Heart and Vasculature. 35, 100842.

      Research output: Contribution to journal › Journal article › Research › peer-review

    91. Published

      Inherited Cardiac Diseases Caused by Mutations in the Nav1.5 Sodium Channel

      Tfelt-Hansen, J., Winkel, B. G., Grunnet, Morten & Jespersen, Thomas, 2009, In: Cardiovascular Electrophysiology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      Inherited cardiac diseases caused by mutations in the Nav1.5 sodium channel.

      Tfelt-Hansen, Jacob, Winkel, B., Grunnet, Morten & Jespersen, Thomas, Oct 2009, In: Journal of Cardiovascular Electrophysiology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    93. Published

      Inhibition of Adenosine Pathway Alters Atrial Electrophysiology and Prevents Atrial Fibrillation

      Soattin, Luca, Lubberding, Anniek Frederike, Bentzen, Bo Hjorth, Christ, T. & Jespersen, Thomas, 2020, In: Frontiers in Physiology. 11, 14 p., 493.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Published

      Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During beta-Adrenergic and Muscarinic Receptor Activation

      Skibsbye, L., Bengaard, A. K., Uldum-Nielsen, A. M., Boddum, K., Christ, T. & Jespersen, Thomas, 2018, In: Frontiers in Physiology. 9

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. Published

      Inhibition of Small-Conductance Calcium-Activated Potassium Current (IK,Ca) Leads to Differential Atrial Electrophysiological Effects in a Horse Model of Persistent Atrial Fibrillation

      Fenner, Merle Friederike, Gatta, G., Sattler, Stefan M, Kuiper, M., Hesselkilde, E. M., Adler, Ditte Marie Top, Smerup, Morten Holdgaard, Schotten, U., Sørensen, U., Diness, J. G., Jespersen, Thomas, Verheule, S., Van Hunnik, A. & Buhl, Rikke, 2021, In: Frontiers in Physiology. 12, 614483.

      Research output: Contribution to journal › Journal article › Research › peer-review

    96. Published

      Inhibition of small-conductance Ca2+-activated K+ channels terminates and protects against atrial fibrillation

      Diness, Jonas Goldin, Sørensen, U. S., Nissen, J. D., Al-Shahib, B., Jespersen, T., Grunnet, Morten, Hansen, R. S. & Jespersen, Thomas, Aug 2010, In: Circulation. Arrhythmia and electrophysiology. 3, 4, p. 380-90 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    97. Published

      Inhibition of sodium-proton-exchanger subtype 3-mediated sodium absorption in the gut: A new antihypertensive concept

      Linz, Benedikt Maximilian, Saljic, Arnela, Hohl, M., Gawalko, M., Jespersen, Thomas, Sanders, P., Bohm, M. & Dr Linz, Dominik Karl, 2020, In: IJC Heart and Vasculature. 29, 7 p., 100591.

      Research output: Contribution to journal › Review › Research › peer-review

    98. E-pub ahead of print

      Inhibition of the acetylcholine-regulated potassium current prevents transient apnea-related atrial arrhythmogenic changes in a porcine model

      Hertel, Julie Norup, Linz, Benedikt Maximilian, Isaksen, Jonas L., Jerltorp, Kezia, Leonhardt, C., Gottlieb, Lisa Amalie, Saljic, Arnela, Jespersen, Thomas & Dr Linz, Dominik Karl, 2024, (E-pub ahead of print) In: Heart Rhythm.

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Published

      Intrinsic Electrical Remodeling Underlies Atrioventricular Block in Athletes

      Mesirca, P., Nakao, S., Nissen, S. D., Forte, G., Anderson, C., Trussell, T., Li, J., Cox, C., Zi, M., Logantha, S., Yaar, S., Cartensen, H., Bidaud, I., Stuart, L., Soattin, L., Morris, G. M., Da Costa Martins, P. A., Cartwright, E. J., Oceandy, D., Mangoni, M. E. & 5 others, Jespersen, Thomas, Buhl, Rikke, Dobrzynski, H., Boyett, M. R. & D'Souza, A., 2021, In: Circulation Research. 129, 1, p. E1-E20

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Published

      Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada Syndrome mutant

      Yuan, L., Koivumaki, J., Liang, B., Lorentzen, L. G., Tang, C., Andersen, M. N., Svendsen, Jesper Hastrup, Tfelt-Hansen, J., Maleckar, M., Schmitt, Nicole, Olesen, Morten Steen Salling & Jespersen, Thomas, 21 Feb 2014, In: American Journal of Physiology: Heart and Circulatory Physiology. 306, 8, p. H1204-12

      Research output: Contribution to journal › Journal article › Research › peer-review

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