From CMR Image to Patient-Specific Simulation and Population-Based Analysis: Tutorial for an Openly Available Image-Processing Pipeline

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Cardiac magnetic resonance (CMR) imaging is becoming a routine diagnostic and therapy planning tool for some cardiovascular diseases. It is still challenging to properly analyse the acquired data, and the currently available measures do not exploit the rich characteristics of that data. Advanced analysis and modelling techniques are increasingly used to extract additional information from the images, in order to define metrics describing disease manifestations and to quantitatively compare patients. Many techniques share a common bottleneck caused by the image processing required to segment the images and convert the segmentation to a usable computational domain for analysis/modelling. To address this, we present a comprehensive pipeline to go from CMR images to computational bi-ventricle meshes. The latter can be used for biophysical simulations or statistical shape analysis. The provided tutorial describes each step and the proposed pipeline, which makes use of tools that are available open-source. The pipeline was applied to a data-set of myocardial infarction patients, from late gadolinium enhanced CMR images, to analyse and compare structure in these patients. Examples of applications present the use of the output of the pipeline for patient-specific biophysical simulations and population-based statistical shape analysis.

Original languageEnglish
Title of host publicationStatistical Atlases and Computational Models of the Heart : Imaging and Modelling Challenges - 7th International Workshop, STACOM 2016 Held in Conjunction with MICCAI 2016, Revised Selected Papers
Number of pages12
PublisherSpringer
Publication date1 Jan 2017
Pages106-117
ISBN (Print)9783319527178
DOIs
Publication statusPublished - 1 Jan 2017
Event7th International Workshop on Statistical Atlases and Computational Models of the Heart Imaging and Modelling Challenges, STACOM 2016 Held in Conjunction with 19th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2016 - Athens, Greece
Duration: 17 Oct 201621 Oct 2016

Conference

Conference7th International Workshop on Statistical Atlases and Computational Models of the Heart Imaging and Modelling Challenges, STACOM 2016 Held in Conjunction with 19th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2016
LandGreece
ByAthens
Periode17/10/201621/10/2016
SponsorSciMedia Ltd, SysAfib
SeriesLecture Notes in Computer Science
Volume10124 LNCS
ISSN0302-9743

ID: 203873588