A Multiple Kernel Learning Framework to Investigate the Relationship Between Ventricular Fibrillation and First Myocardial Infarction

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

Myocardial infarction results in changes in the structure and tissue deformation of the ventricles. In some cases, the development of the disease may trigger an arrhythmic event, which is a major cause of death within the first twenty four hours after the infarction. Advanced analysis methods are increasingly used in order to discover particular characteristics of the myocardial infarction development that lead to the occurrence of arrhythmias. However, such methods usually consider only a single feature or combine separate analyses from multiple features in the analytical process. In an attempt to address this, we propose to use cardiac magnetic resonance imaging to extract data on the shape of the ventricles and volume and location of the infarct zone, and to combine them within one analytical model through a multiple kernel learning framework. The proposed method was applied to a cohort of 46 myocardial infarction patients. The location, rather than the volume, of the infarct region was found to be correlated with arrhythmic events and the proposed combination of kernels yielded excellent accuracy (100%) in distinguishing between patients that did and did not present at the hospital with ventricular fibrillation.

Original languageEnglish
Title of host publicationFunctional Imaging and Modelling of the Heart : 9th International Conference, FIMH 2017, Toronto, ON, Canada, June 11-13, 2017, Proceedings
Number of pages11
PublisherSpringer
Publication date1 Jan 2017
Pages161-171
ISBN (Print)9783319594477
DOIs
Publication statusPublished - 1 Jan 2017
Event9th International Conference on Functional Imaging and Modelling of the Heart, FIMH 2017 - Toronto, Canada
Duration: 11 Jun 201713 Jun 2017

Conference

Conference9th International Conference on Functional Imaging and Modelling of the Heart, FIMH 2017
LandCanada
ByToronto
Periode11/06/201713/06/2017
Sponsoret al., GE HealthCare, Imricor, Inria, SciMedia Ltd, Shelly Medical Imaging Technologies
SeriesLecture Notes in Computer Science
Volume10263 LNCS
ISSN0302-9743

ID: 203873769