Nils Billestrup
Professor
- Published
Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling
Adams, T. E., Hansen, J. A., Starr, R., Nicola, N. A., Hilton, D. J. & Billestrup, Nils, 16 Jan 1998, In: The Journal of Biological Chemistry. 273, 3, p. 1285-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of phenylalanine 346 in the rat growth hormone receptor as being critical for ligand-mediated internalization and down-regulation
Allevato, G., Billestrup, Nils, Goujon, L., Galsgaard, E. D., Norstedt, G., Postel-Vinay, M. C., Kelly, P. A. & Nielsen, Jens Høiriis, 21 Jul 1995, In: The Journal of Biological Chemistry. 270, 29, p. 17210-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone, interferon-gamma, and leukemia inhibitory factor promoted tyrosyl phosphorylation of insulin receptor substrate-1
Argetsinger, L. S., Hsu, G. W., Myers, M. G., Billestrup, Nils, White, M. F. & Carter-Su, C., 16 Jun 1995, In: The Journal of Biological Chemistry. 270, 24, p. 14685-92 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling
Argetsinger, L. S., Norstedt, G., Billestrup, Nils, White, M. F. & Carter-Su, C., 15 Nov 1996, In: The Journal of Biological Chemistry. 271, 46, p. 29415-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pituitary mammosomatotroph adenomas develop in old mice transgenic for growth hormone-releasing hormone
Asa, S. L., Kovacs, K., Stefaneanu, L., Horvath, E., Billestrup, Nils, Gonzalez-Manchon, C. & Vale, W., Mar 1990, In: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 193, 3, p. 232-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pituitary adenomas in mice transgenic for growth hormone-releasing hormone
Asa, S. L., Kovacs, K., Stefaneanu, L., Horvath, E., Billestrup, Nils, Gonzalez-Manchon, C. & Vale, W., Nov 1992, In: Endocrinology. 131, 5, p. 2083-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Growth hormone (GH)-independent dimerization of GH receptor by a leucine zipper results in constitutive activation
Behncken, S. N., Billestrup, Nils, Brown, R., Amstrup, J., Conway-Campbell, B. & Waters, M. J., 2 Jun 2000, In: The Journal of Biological Chemistry. 275, 22, p. 17000-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pannexin-2-deficiency sensitizes pancreatic beta-cells to cytokine-induced apoptosis in vitro and impairs glucose tolerance in vivo
Berchtold, L. A., Miani, M., Diep, T. A., Madsen, A. N., Cigliola, V., Colli, M., Miskovic Krivokapic, Jelena, Pociot, Flemming, Eizirik, D. L., Meda, P., Holst, Birgitte, Billestrup, Nils & Storling, J., 2017, In: Molecular and Cellular Endocrinology. 448, p. 108-121 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The stimulatory effect of growth hormone, prolactin, and placental lactogen on beta-cell proliferation is not mediated by insulin-like growth factor-I
Billestrup, Nils & Nielsen, Jens Høiriis, Aug 1991, In: Endocrinology. 129, 2, p. 883-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone receptor C-terminal domains required for growth hormone-induced intracellular free Ca2+ oscillations and gene transcription
Billestrup, Nils, Bouchelouche, P., Allevato, G., Ilondo, M. & Nielsen, Jens Høiriis, 28 Mar 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 7, p. 2725-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth of the endocrine pancreas: the role of somatolactogenic hormones and receptors
Billestrup, Nils, Møldrup, A., Allevato, G., Petersen, Erik Brinch, Pedersen, Johan, Hansen, J. A. & Nielsen, Jens Høiriis, Feb 1993, In: Biochemical Society Transactions. 21, 1, p. 146-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular dissection of the growth hormone receptor. Identification of distinct cytoplasmic domains corresponding to different signaling pathways
Billestrup, Nils, Allevato, G., Møldrup, A., Galsgaard, E. D., Amstrup, J., Hansen, J. A., Svensson, C. & Nielsen, Jens Høiriis, 7 Sep 1995, In: Annals of the New York Academy of Sciences. 766, p. 481-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Introduction of exogenous growth hormone receptors augments growth hormone-responsive insulin biosynthesis in rat insulinoma cells
Billestrup, Nils, Møldrup, A., Serup, Palle, Mathews, L. S., Norstedt, G. & Nielsen, Jens Høiriis, Sep 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 18, p. 7210-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanism of growth hormone signalling
Billestrup, Nils, Hansen, J. A., Hansen, L. H., Møldrup, A., Galsgaard, E. D. & Nielsen, Jens Høiriis, Apr 1998, In: Endocrine Journal. 45 Suppl, p. S41-5Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of intracellular domains in the growth hormone receptor involved in signal transduction
Billestrup, Nils, Allevato, G., Norstedt, G., Møldrup, A. & Nielsen, Jens Høiriis, Jul 1994, In: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 206, 3, p. 205-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone-releasing factor induces c-fos expression in cultured primary pituitary cells
Billestrup, Nils, Mitchell, R. L., Vale, W. & Verma, I. M., Apr 1987, In: Molecular endocrinology (Baltimore, Md.). 1, 4, p. 300-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ID'ing a novel inhibitor of β-cell function, Id1
Billestrup, Nils, Oct 2011, In: Diabetes. 60, 10, p. 2455-6 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitro
Billestrup, Nils, Swanson, L. W. & Vale, W., Sep 1986, In: Proceedings of the National Academy of Sciences of the United States of America. 83, 18, p. 6854-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone binding to specific receptors stimulates growth and function of cloned insulin-producing rat insulinoma RIN-5AH cells
Billestrup, Nils & Martin, J. M., Mar 1985, In: Endocrinology. 116, 3, p. 1175-81 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human growth hormone binding and stimulation of insulin biosynthesis in cloned rat insulinoma cells
Billestrup, Nils, 1985, In: Biomedica Biochimica Acta. 44, 1, p. 85-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of somatotroph growth and growth hormone biosynthesis by activin in vitro
Billestrup, Nils, González-Manchón, C., Potter, E. & Vale, W., Feb 1990, In: Molecular endocrinology (Baltimore, Md.). 4, 2, p. 356-62 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dedifferentiation for replication of human beta-cells: a division between mice and men?
Billestrup, Nils & Otonkoski, T., 2008, In: Diabetes. 57, 6, p. 1457-8 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CRFR1 activation protects against cytokine-induced beta cell death
Blaabjerg, L., Christensen, G. L., Matsumoto, M., van der Meulen, T., Huising, M. O., Billestrup, Nils & Vale, W., 16 Oct 2014, In: Journal of Molecular Endocrinology. 53, p. 417-427 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells
Bruun, C., Heding, P. E., Rønn, S. G., Frobøse, H., Rhodes, C. J., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2009, In: Molecular and Cellular Endocrinology. 311, 1-2, p. 32-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of beta cell growth and function by bone morphogenetic proteins
Bruun, C., Christensen, G. L., Jacobsen, M. L. B., Kanstrup, M. B., Jensen, P. R., Fjordvang, H., Mandrup-Poulsen, Thomas & Billestrup, Nils, 27 Sep 2014, In: Diabetologia. 57, 12, p. 2546-54 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ß-cell specific overexpression of suppressor of cytokine signalling-3 does not protect against multiple low dose streptozotocin induced type 1 diabetes in mice
Börjesson, A., Rønn, S. G., Karlsen, A. E., Billestrup, Nils & Sandler, S., 30 Apr 2011, In: Immunology Letters. 136, 1, p. 74-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone and prolactin stimulate the expression of rat preadipocyte factor-1/delta-like protein in pancreatic islets: molecular cloning and expression pattern during development and growth of the endocrine pancreas
Carlsson, C., Tornehave, D., Lindberg, K., Galante, P., Billestrup, Nils, Michelsen, B., Larsson, L. I. & Nielsen, Jens Høiriis, Sep 1997, In: Endocrinology. 138, 9, p. 3940-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus
Christensen, D. P., Dahllöf, M. S., Lundh, M., Rasmussen, D. N., Nielsen, M. D., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 2011, In: Molecular Medicine. 17, 5-6, p. 378-90 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection
Christensen, D. P., Gysemans, C., Lundh, M., Dahllöf, M. S., Noesgaard, D., Schmidt, S. F., Mandrup, S., Birkbak, N., Workman, C., Piemonti, L., Blaabjerg, L., Monzani, V., Fossati, G., Mascagni, P., Paraskevas, S., Aikin, R. A., Billestrup, N., Grunnet, L. G., Dinarello, C. A., Mathieu, C. & 1 others, , 6 Jan 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 3, p. 1055-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bone morphogenetic protein 4 inhibits insulin secretion from rodent beta cells through regulation of calbindin1 expression and reduced voltage-dependent calcium currents
Christensen, G. L., Jacobsen, M. L. B., Wendt, A., Mollet, I. G., Friberg, J., Frederiksen, K. S., Meyer, M., Bruun, C., Eliasson, L. & Billestrup, Nils, Jun 2015, In: Diabetologia. 58, 6, p. 1282-1290 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone receptor expression and function in pituitary adenomas
Clausen, L. R., Kristiansen, M. T., Rasmussen, L. M., Billestrup, Nils, Blaabjerg, O., Ledet, T. & Jørgensen, J. O. L., May 2004, In: Clinical Endocrinology. 60, 5, p. 576-83 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells
Collombat, P., Xu, X., Ravassard, P., Sosa-Pineda, B., Dussaud, S., Billestrup, Nils, Madsen, O. D., Serup, P., Heimberg, H. & Mansouri, A., 2009, In: Cell. 138, 3, p. 449-62 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preparation of 125I-protein A usable for up to 10 months in immunoassays
Dyrberg, T. & Billestrup, Nils, 6 Jul 1984, In: Journal of Immunological Methods. 71, 2, p. 193-201 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deficient SOCS3 and SHP-1 Expression in Psoriatic T Cells
Eriksen, K. W., Woetmann, Anders , Skov, Lone, Krejsgaard, T., Bovin, L. F., Hansen, M. L., Grønbæk, Kirsten, Billestrup, Nils, Nissen, Mogens Holst, Geisler, Carsten, Wasik, M. A. & Ødum, Niels, 2010, In: Journal of Investigative Dermatology. 130, 6, p. 1590-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Signal transducer and activator of transcription 5 activation is sufficient to drive transcriptional induction of cyclin D2 gene and proliferation of rat pancreatic beta-cells
Friedrichsen, B. N., Richter, H. E., Hansen, J. A., Rhodes, C. J., Nielsen, Jens Høiriis, Billestrup, Nils & Møldrup, A., May 2003, In: Molecular endocrinology (Baltimore, Md.). 17, 5, p. 945-58 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dissociation between skeletal muscle inhibitor-{kappa}B kinase/nuclear factor-{kappa}B pathway activity and insulin sensitivity in nondiabetic twins
Friedrichsen, M., Ribel-Madsen, R., Wojtaszewski, Jørgen F P, Grunnet, Louise Groth, Richter, Erik A., Billestrup, Nils, Ploug, Thorkil, Vaag, A. & Poulsen, P., 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 1, p. 414-421 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a growth hormone-responsive STAT5-binding element in the rat insulin 1 gene
Galsgaard, E. D., Gouilleux, F., Groner, B., Serup, Palle, Billestrup, Nils & Nielsen, Jens Høiriis, Jun 1996, In: Molecular endocrinology (Baltimore, Md.). 10, 6, p. 652-60 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of glucose transport and c-fos and egr-1 expression in cells with mutated or endogenous growth hormone receptors
Gong, T. W., Meyer, D. J., Liao, J., Hodge, C. L., Campbell, G. S., Wang, X., Billestrup, Nils, Carter-Su, C. & Schwartz, J., Apr 1998, In: Endocrinology. 139, 4, p. 1863-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling
Greenhalgh, C. J., Metcalf, D., Thaus, A. L., Corbin, J. E., Uren, R., Morgan, P. O., Fabri, L. J., Zhang, J., Martin, H. M., Willson, T. A., Billestrup, Nils, Nicola, N. A., Baca, M., Alexander, W. S. & Hilton, D. J., 25 Oct 2002, In: The Journal of Biological Chemistry. 277, 43, p. 40181-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proinflammatory cytokines activate the intrinsic apoptotic pathway in beta-cells
Grunnet, L. G., Aikin, R., Tonnesen, M. F., Paraskevas, S., Blaabjerg, L., Størling, J., Rosenberg, L., Billestrup, Nils, Maysinger, D. & Mandrup-Poulsen, Thomas, 2009, In: Diabetes. 58, 8, p. 1807-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity
Gylvin, T., Nolsøe, R., Hansen, Torben, Nielsen, E. M. D., Bergholdt, R., Karlsen, A. E., Billestrup, Nils, Borch-Johnsen, K., Pedersen, O., Mandrup-Poulsen, Thomas, Nerup, J. & Pociot, Flemming, 1 Jul 2004, In: Diabetologia. 47, 7, p. 1273-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth arrest specific protein (GAS) 6: a role in the regulation of proliferation and functional capacity of the perinatal rat beta cell
Haase, T. N., Rasmussen, M., Jaksch, C. A. M., Gaarn, L. W., Petersen, C. K., Billestrup, Nils & Nielsen, Jens Høiriis, Apr 2013, In: Diabetologia. 56, 4, p. 763-773 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The mitogenic effect of Gas6 on pancreatic beta cells is mediated via the receptor tyrosine kinase Axl
Haase, T. N., Gustafsson, A., Nalla, A., Ringholm, L., Damm, Peter, Mathiesen, Elisabeth, Dahlback, B., Billestrup, Nils & Nielsen, Jens Høiriis, Sep 2014, In: Diabetologia. 57, 1 Suppl, p. S173-S174 408.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The role of GH receptor tyrosine phosphorylation in Stat5 activation
Hansen, J. A., Hansen, Lars Hestbjerg, Wang, X., Kopchick, J. J., Gouilleux, F., Groner, B., Møldrup, A., Galsgaard, E. D., Nielsen, Jens Høiriis & Billestrup, Nils, Jun 1997, In: Journal of Molecular Endocrinology. 18, 3, p. 213-21 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins
Hansen, J. A., Lindberg, K., Hilton, D. J., Nielsen, Jens Høiriis & Billestrup, Nils, Nov 1999, In: Molecular endocrinology (Baltimore, Md.). 13, 11, p. 1832-43 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Divalent metal transporter 1 regulates iron-mediated ROS and pancreatic ß cell fate in response to cytokines
Hansen, J. B., Tonnesen, M. F., Madsen, A. N., Hagedorn, P., Friberg, J., Grunnet, L. G., Heller, R. S., Nielsen, A. Ø., Størling, J., Baeyens, L., Anker-Kitai, L., Qvortrup, K., Bouwens, L., Efrat, S., Aalund, M., Andrews, N. C., Billestrup, N., Karlsen, A. E., Holst, B., Pociot, F. & 1 others, , 2012, In: Cell Metabolism. 16, 4, p. 449-61 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Genetic deficiency of tissue inhibitor of metalloproteinase (TIMP) 1 does not affect apoptosis in cytokine-exposed mouse islets in vitro.
Hansen, J. B., Tonnesen, M. F., Rømer, M. U. K., Billestrup, Nils, Brunner, N. & Mandrup-Poulsen, Thomas, 2010, (Accepted/In press).Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Characterization of the inhibitory effect of growth hormone on primary preadipocyte differentiation
Hansen, L. H., Madsen, B., Teisner, B., Nielsen, Jens Høiriis & Billestrup, Nils, Aug 1998, In: Molecular endocrinology (Baltimore, Md.). 12, 8, p. 1140-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation
Hansen, L. H., Wang, X., Kopchick, J. J., Bouchelouche, P., Galsgaard, E. D., Nielsen, Jens Høiriis & Billestrup, Nils, 24 May 1996, In: The Journal of Biological Chemistry. 271, 21, p. 12669-73 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CRFR1 is expressed on pancreatic beta cells, promotes beta cell proliferation, and potentiates insulin secretion in a glucose-dependent manner
Huising, M. O., van der Meulen, T., Vaughan, J. M., Matsumoto, M., Donaldson, C. J., Park, H., Billestrup, Nils & Vale, W. W., 2009, In: Proceedings of the National Academy of Science of the United States of America. 107, 2, p. 912-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-1beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells
Jacobsen, M. L. B., Rønn, S. G., Bruun, C., Larsen, C. M., Eizirik, D. L., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2008, In: Diabetologia. 52, 2, p. 281-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-1 beta-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells
Jacobsen, M. L. B., Ronn, S. G., Bruun, C., Larsen, C. M., Eizirik, D. L., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2009, In: Diabetologia. 52, 2, p. 281-288 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GH receptor signaling in skeletal muscle and adipose tissue in human subjects following exposure to an intravenous GH bolus
Jørgensen, J. O. L., Jessen, N., Pedersen, S. B., Vestergaard, E. T., Gormsen, L. C., Lund, S. & Billestrup, Nils, 1 Nov 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 5, p. E899-905Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of growth hormone on glucose and fat metabolism in human subjects
Jørgensen, J. O. L., Møller, L., Krag, M. B., Billestrup, Nils & Christiansen, J. K. S., 1 Mar 2007, In: Endocrinology & Metabolism Clinics of North America. 36, 1, p. 75-87 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Compartmentalization of GABA synthesis by GAD67 differs between pancreatic beta cells and neurons
Kanaani, J., Cianciaruso, C., Phelps, E. A., Pasquier, M., Brioudes, E., Billestrup, Nils & Baekkeskov, S., 2015, In: PLOS ONE. 10, 2, p. 1-24 24 p., e0117130.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the Molecular Mechanisms Underlying Glucose Stimulated Insulin Secretion from Isolated Pancreatic β-cells Using Post-translational Modification Specific Proteomics (PTMomics)
Kang, T., Jensen, P., Huang, H., Lund Christensen, G., Billestrup, Nils & Larsen, M. R., Jan 2018, In: Molecular and Cellular Proteomics. 17, 1, p. 95-110 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kappaB-regulated proapoptotic pathways
Karlsen, A. E., Heding, P. E., Frobøse, H., Rønn, S. G., Kruhøffer, M., Orntoft, T. F., Darville, M., Eizirik, D. L., Pociot, Flemming, Nerup, J., Mandrup-Poulsen, Thomas & Billestrup, Nils, 1 Nov 2004, In: Diabetologia. 47, 11, p. 1998-2011 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct cytoplasmic domains of the growth hormone receptor are required for glucocorticoid- and phorbol ester-induced decreases in growth hormone (GH) binding. These domains are different from that reported for GH-induced receptor internalization
King, A. P., Tseng, M. J., Logsdon, C. D., Billestrup, Nils & Carter-Su, C., 26 Jul 1996, In: The Journal of Biological Chemistry. 271, 30, p. 18088-94 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct demonstration of NCAM cis-dimerization and inhibitory effect of palmitoylation using the BRET2 technique
Kulahin, N., Grunnet, L. G., Lundh, M., Christensen, D. P., Jorgensen, R., Heding, A., Billestrup, Nils, Berezin, V., Bock, E. & Mandrup-Poulsen, Thomas, 3 Jan 2011, In: FEBS Letters. 585, 1, p. 58-64 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth arrest- and DNA-damage-inducible 45beta gene inhibits c-Jun N-terminal kinase and extracellular signal-regulated kinase and decreases IL-1beta-induced apoptosis in insulin-producing INS-1E cells
Larsen, C. M., Døssing, M. G., Papa, S., Franzoso, G., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 May 2006, In: Diabetologia. 49, 5, p. 980-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells
Larsen, L., Tonnesen, M., Ronn, S. G., Størling, Joachim, Jørgensen, S., Mascagni, P., Dinarello, C. A., Billestrup, Nils & Mandrup-Poulsen, Thomas, Apr 2007, In: Diabetologia. 50, 4, p. 779-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor kappaB-mediated gene expression in insulin-producing INS-1E cells
Larsen, L., Størling, Joachim, Darville, M., Eizirik, D. L., Bonny, C., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 Dec 2005, In: Diabetologia. 48, 12, p. 2582-90 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developmental expression of proprotein convertase 1/3 in the rat
Lee, Y. C., Damholt, A. B., Billestrup, Nils, Kisbye, T., Galante, P., Michelsen, B., Kofod, H. & Nielsen, Jens Høiriis, 10 Sep 1999, In: Molecular and Cellular Endocrinology. 155, 1-2, p. 27-35 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of pancreatic beta-cell mass and proliferation by SOCS-3
Lindberg, K., Rønn, S. G., Tornehave, D., Richter, H., Hansen, J. A., Rømer, J., Jackerott, M. & Billestrup, Nils, Oct 2005, In: Journal of Molecular Endocrinology. 35, 2, p. 231-43 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone is a growth factor for the differentiated pancreatic beta-cell
Linde, S., Welinder, B. S., Billestrup, Nils, Madsen, O. D. & Nielsen, Jens Høiriis, Jan 1989, In: Molecular endocrinology (Baltimore, Md.). 3, 1, p. 165-73 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Requirement of tyrosine residues 333 and 338 of the growth hormone (GH) receptor for selected GH-stimulated function
Lobie, P. E., Allevato, G., Norstedt, G., Billestrup, Nils & Nielsen, Jens Høiriis, 15 Sep 1995, In: The Journal of Biological Chemistry. 270, 37, p. 21745-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cellular mechanism of growth hormone signal transduction
Lobie, P. E., Wood, T. J., Sliva, D., Billestrup, Nils, Waters, M. J., Enberg, B. & Norstedt, G., Dec 1994, In: Acta Paediatrica. Supplement. 406, p. 39-46; discussion 47Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism of protein tyrosine phosphatase 1B-mediated inhibition of leptin signalling
Lund, I. K., Hansen, J. A., Andersen, H. S., Møller, N. P. H. & Billestrup, Nils, 1 Apr 2005, In: Journal of Molecular Endocrinology. 34, 2, p. 339-51 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Surface-expressed insulin receptors as well as IGF-I receptors both contribute to the mitogenic effects of human insulin and its analogues
Lundby, A., Bolvig, P., Hegelund, A. C., Hansen, B. F., Worm, J., Lützen, A., Billestrup, Nils, Bonnesen, C. & Oleksiewicz, M. B., Jul 2015, In: Journal of Applied Toxicology. 35, 7, p. 842-850 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines
Lundh, M., Christensen, D. P., Rasmussen, D. N., Mascagni, P., Dinarello, C. A., Billestrup, Nils, Grunnet, L. G. & Mandrup-Poulsen, Thomas, 1 Dec 2010, In: Diabetologia. 53, 12, p. 2569-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nuclear translocation and retention of growth hormone
Mertani, H. C., Raccurt, M., Abbate, A., Kindblom, J., Törnell, J., Billestrup, Nils, Usson, Y., Morel, G. & Lobie, P. E., Jul 2003, In: Endocrinology. 144, 7, p. 3182-95 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of fasting on growth hormone signaling and action in muscle and fat
Moller, L., Dalman, L., Norrelund, H., Billestrup, Nils, Frystyk, J., Moller, N. & Jorgensen, J. O. L., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 3, p. 965-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiple growth hormone-binding proteins are expressed on insulin-producing cells
Møldrup, A., Billestrup, Nils, Thorn, N. A., Lernmark, A. & Nielsen, Jens Høiriis, Aug 1989, In: Molecular endocrinology (Baltimore, Md.). 3, 8, p. 1173-82 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rat insulinoma cells express both a 115-kDa growth hormone receptor and a 95-kDa prolactin receptor structurally related to the hepatic receptors
Møldrup, A., Billestrup, Nils & Nielsen, Jens Høiriis, 25 May 1990, In: The Journal of Biological Chemistry. 265, 15, p. 8686-90 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone action in rat insulinoma cells expressing truncated growth hormone receptors
Møldrup, A., Allevato, G., Dyrberg, T., Billestrup, Nils & Nielsen, Jens Høiriis, 15 Sep 1991, In: The Journal of Biological Chemistry. 266, 26, p. 17441-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of the growth hormone receptor gene in insulin producing cells
Møldrup, A., Billestrup, Nils & Nielsen, Jens Høiriis, 1990, In: Biomedica Biochimica Acta. 49, 12, p. 1151-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implications for the offspring of circulating factors involved in beta cell adaptation in pregnancy
Nalla, A., Ringholm, L., Søstrup, B., Højrup, P., Thim, L., Levery, S. B., Vakhrushev, Sergey, Billestrup, Nils, Mathiesen, Elisabeth, Damm, Peter & Nielsen, Jens Høiriis, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1181-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of fetal and neonatal environment on beta cell function and development of diabetes
Nielsen, Jens Høiriis, Haase, T. N., Jaksch, C., Nalla, A., Søstrup, B., Nalla, A. A., Larsen, L., Rasmussen, M., Dalgaard, L. T., Gaarn, L. W., Thams, P., Kofod, H. & Billestrup, Nils, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1109-22 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beta cell proliferation and growth factors
Nielsen, Jens Høiriis, Svensson, C., Møldrup, A., Galsgaard, E. D. & Billestrup, Nils, Jan 1999, In: Journal of Molecular Medicine. 77, 1, p. 62-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of growth hormone and prolactin in beta cell growth and regeneration
Nielsen, Jens Høiriis, Møldrup, A., Billestrup, Nils, Petersen, E. D., Allevato, G. & Stahl, M., 1992, Pancreatic islet cell regeneration and growth. Vol. 321. p. 9-17; discussion 19-20 (Advances in Experimental Medicine and Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Regulation of Pancreatic α-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro
Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of Pancreatic Alpha Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) in vitro.
Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p., 27479530 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and characterization of a pituitary corticotropin-releasing factor binding protein by chemical cross-linking
Nishimura, E., Billestrup, Nils, Perrin, M. & Vale, W., 25 Sep 1987, In: The Journal of Biological Chemistry. 262, 27, p. 12893-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell transfection as a tool to study growth hormone action
Norstedt, G., Enberg, B., Francis, S., Hansson, A., Hulthén, A., Lobie, P. E., Sliva, D., Wood, T. J. & Billestrup, Nils, Jul 1994, In: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 206, 3, p. 181-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proliferation of sorted human and rat beta cells
Parnaud, G., Bosco, D., Berney, T., Pattou, F., Kerr-Conte, J., Donath, M. Y., Bruun, C., Mandrup-Poulsen, Thomas, Billestrup, Nils & Halban, P. A., 2008, In: Diabetologia. 51, 1, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells
Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Williams, K., Barrès, Romain & Billestrup, Nils, 2022, In: Journal of Biological Chemistry. 298, 9, 14 p., 102312.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted Delivery of Butyrate Improves Glucose Homeostasis, Reduces Hepatic Lipid Accumulation and Inflammation in db/db Mice
Pedersen, Signe Schultz, Prause, Michala Cecilie Burstein, Sørensen, C., Størling, Joachim, Moritz, Thomas, Mariño, E. & Billestrup, Nils, 2023, In: International Journal of Molecular Sciences. 24, 5, 17 p., 4533.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Butyrate functions as a histone deacetylase inhibitor to protect pancreatic beta cells from IL-1β-induced dysfunction
Pedersen, Signe Schultz, Ingerslev, Lars Roed, Olsen, M., Prause, Michala Cecilie Burstein & Billestrup, Nils, 2024, In: FEBS Journal. 291, 3, p. 566-583Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of growth hormone and serum on the expression of the proto-oncogenes c-jun and c-fos in insulin producing cells
Petersen, E. D., Billestrup, Nils & Nielsen, Jens Høiriis, 1990, In: Biomedica Biochimica Acta. 49, 12, p. 1171-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-1beta-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line
Petersen, L. G., Størling, Joachim, Heding, P., Li, S., Berezin, V., Saldeen, J., Billestrup, Nils, Bock, E. & Mandrup-Poulsen, Thomas, 2006, In: Diabetologia. 49, 8, p. 1864-75 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aberrant accumulation of the diabetes autoantigen GAD65 in Golgi membranes in conditions of ER stress and autoimmunity
Phelps, E. A., Cianciaruso, C., Michael, I. P., Pasquier, M., Kanaani, J., Nano, R., Lavallard, V., Billestrup, Nils, Hubbell, J. A. & Baekkeskov, S., Sep 2016, In: Diabetes. 65, 9, p. 2686-2699Research output: Contribution to journal › Journal article › Research › peer-review
- Published
JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis
Prause, Michala Cecilie Burstein, Christensen, D. P., Billestrup, Nils & Mandrup-Poulsen, Thomas, 2014, In: PLOS ONE. 9, 1, p. 1-11 11 p., e87067.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Butyrate protects pancreatic beta cells from cytokine-induced dysfunction
Prause, Michala Cecilie Burstein, Pedersen, Signe Schultz, Tsonkova, V., Qiao, M. & Billestrup, Nils, 2021, In: International Journal of Molecular Sciences. 22, 19, 18 p., 10427.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TRAF2 mediates JNK and STAT3 activation in response to IL-1β and IFNγ and facilitates apoptotic death of insulin-producing β-cells
Prause, Michala Cecilie Burstein, Berchtold, L. A., Urizar, A. I., Trauelsen, Mette, Billestrup, Nils, Mandrup-Poulsen, Thomas & Størling, Joachim, 15 Jan 2016, In: Molecular and Cellular Endocrinology. 420, p. 24-36 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1 beta-Induced Apoptosis Associated with Abrogated Myc Expression
Prause, Michala Cecilie Burstein, Mayer, C. M., Brorsson, C., Frederiksen, K. S., Billestrup, Nils, Størling, Joachim & Mandrup-Poulsen, Thomas, 2016, In: Journal of Diabetes Research. 2016, 15 p., 1312705.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes
Reinhard, H., Jacobsen, P. K., Lajer, M., Pedersen, N., Billestrup, Nils, Mandrup-Poulsen, Thomas, Parving, H. & Rossing, Peter, 1 Oct 2010, In: Diabetologica. 53, 10, p. 2129-33 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endothelial Progenitor Cells in Long-Standing Asymptomatic Type 1 Diabetic Patients with or without Diabetic Nephropathy
Reinhard, H., Jacobsen, P. K., Lajer, M., Tarnow, L., Astrup, A. S., Kim, W. Y., Pedersen, N., Billestrup, Nils, Mandrup-Poulsen, Thomas, Parving, H. & Rossing, Peter, 2011, In: Nephron Clinical Practice. 118, 3, p. c309-c314 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of signal transducer and activator of transcription 5 in the inhibitory effects of GH on adipocyte differentiation
Richter, H. E., Albrektsen, T. & Billestrup, Nils, Apr 2003, In: Journal of Molecular Endocrinology. 30, 2, p. 139-50 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SOCS-3 is involved in the downregulation of the acute insulin-like effects of growth hormone in rat adipocytes by inhibition of Jak2/IRS-1 signaling
Ridderstråle, M., Amstrup, J., Hilton, D. J., Billestrup, Nils & Tornqvist, H., Mar 2003, In: Hormone and Metabolic Research. Supplement. 35, 3, p. 169-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection
Rønn, S. G., Börjesson, A., Bruun, C., Heding, P. E., Frobøse, H., Mandrup-Poulsen, Thomas, Karlsen, A. E., Rasschaert, J., Sandler, S. & Billestrup, Nils, 2008, In: Diabetologia. 51, 10, p. 1873-1882 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of suppressor of cytokine signaling 3 on GH signaling in beta-cells
Rønn, S. G., Hansen, J. A., Lindberg, K., Karlsen, A. E. & Billestrup, Nils, Sep 2002, In: Molecular endocrinology (Baltimore, Md.). 16, 9, p. 2124-34 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of corticotropin-releasing factor (CRF) target cells and effects of dexamethasone on binding in anterior pituitary using a fluorescent analog of CRF
Schwartz, J., Billestrup, Nils, Perrin, M., Rivier, J. & Vale, W., Nov 1986, In: Endocrinology. 119, 5, p. 2376-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In-vitro and in-vivo studies supporting the therapeutic potential of ZP3022 in diabetes
Skarbaliene, J., Rigbolt, K. T., Fosgerau, K. & Billestrup, Nils, 15 Nov 2017, In: European Journal of Pharmacology. 815, p. 181-189 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Anti-diabetic Effects of GLP-1-gastrin Dual Agonist ZP3022 in ZDF rats
Skarbaliene, J., Secher, T., Jelsing, J., Ansarullah, Neerup, T. S. R., Billestrup, Nils & Fosgerau, K., Jul 2015, In: Peptides. 69, p. 47-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH
Smit, L. S., Meyer, D. J., Billestrup, Nils, Norstedt, G., Schwartz, J. & Carter-Su, C., May 1996, In: Molecular endocrinology (Baltimore, Md.). 10, 5, p. 519-33 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adenohypophysial changes in mice transgenic for human growth hormone-releasing factor: a histological, immunocytochemical, and electron microscopic investigation
Stefaneanu, L., Kovacs, K., Horvath, E., Asa, S. L., Losinski, N. E., Billestrup, Nils, Price, J. & Vale, W., Nov 1989, In: Endocrinology. 125, 5, p. 2710-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B
Stofega, M. R., Herrington, J., Billestrup, Nils & Carter-Su, C., Sep 2000, In: Molecular endocrinology (Baltimore, Md.). 14, 9, p. 1338-50 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt
Størling, Joachim, Binzer, J., Andersson, A., Züllig, R. A., Tonnesen, M., Knudsen, R. L. P., Spinas, G. A., Sandler, S., Billestrup, Nils & Mandrup-Poulsen, Thomas, 1 Oct 2005, In: Diabetologia. 48, 10, p. 2039-50 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-ordinated regulation of neurogenin-3 expression in the maternal and fetal pancreas during pregnancy
Søstrup, B., Gaarn, L. W., Nalla, A., Billestrup, Nils & Nielsen, Jens Høiriis, Nov 2014, In: Acta Obstetricia et Gynecologica Scandinavica. 93, 11, p. 1190-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of Nuclear Factor-kappa B or Bax Prevents Endoplasmic Reticulum Stress-But Not Nitric Oxide-Mediated Apoptosis in INS-1E Cells
Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Storling, J. & Mandrup-Poulsen, Thomas, 2009, In: Endocrinology. 150, 9, p. 4094-4103 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells
Tonnesen, M. F., Grunnet, L. G., Friberg, J., Cardozo, A. K., Billestrup, Nils, Eizirik, D. L., Størling, Joachim & Mandrup-Poulsen, Thomas, Sep 2009, In: Endocrinology. 150, 9, p. 4094-103 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammatory Cytokines Stimulate Bone Morphogenetic Protein-2 Expression and Release from Pancreatic Beta Cells
Urizar, A. I., Friberg, J., Christensen, D. P., Christensen, G. L. & Billestrup, Nils, 1 Jan 2016, In: Journal of Interferon & Cytokine Research. 36, 1, p. 20-29Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beta cell dysfunction induced by bone morphogenetic protein (BMP)-2 is associated with histone modifications and decreased NeuroD1 chromatin binding
Urizar, A. I., Prause, Michala Cecilie Burstein, Ingerslev, L. R., Wortham, M., Sui, Y., Sander, M., Williams, K., Barrès, Romain, Larsen, M. R., Christensen, G. L. & Billestrup, Nils, 2023, In: Cell Death and Disease. 14, 7, 16 p., 399.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1 beta is associated with changes in expression of beta-cell maturity genes and associated histone modifications
Urizar, A. I., Prause, Michala Cecilie Burstein, Wortham, M., Sui, Y., Thams, P., Sander, M., Christensen, G. L. & Billestrup, Nils, 2019, In: Molecular and Cellular Endocrinology. 496, 12 p., 110524 .Research output: Contribution to journal › Review › Research › peer-review
- Published
Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2
VanderKuur, J., Allevato, G., Billestrup, Nils, Norstedt, G. & Carter-Su, C., 31 Mar 1995, In: The Journal of Biological Chemistry. 270, 13, p. 7587-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone-dependent phosphorylation of tyrosine 333 and/or 338 of the growth hormone receptor
VanderKuur, J. A., Wang, X., Zhang, L., Allevato, G., Billestrup, Nils & Carter-Su, C., 15 Sep 1995, In: The Journal of Biological Chemistry. 270, 37, p. 21738-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Domains of the growth hormone receptor required for association and activation of JAK2 tyrosine kinase
VanderKuur, J. A., Wang, X., Zhang, L., Campbell, G. S., Allevato, G., Billestrup, Nils, Norstedt, G. & Carter-Su, C., 26 Aug 1994, In: The Journal of Biological Chemistry. 269, 34, p. 21709-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for association of the cloned liver growth hormone receptor with a tyrosine kinase
Wang, X., Uhler, M. D., Billestrup, Nils, Norstedt, G., Talamantes, F., Nielsen, Jens Høiriis & Carter-Su, C., 25 Aug 1992, In: The Journal of Biological Chemistry. 267, 24, p. 17390-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 15311848
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JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1 beta-Induced Apoptosis Associated with Abrogated Myc Expression
Research output: Contribution to journal › Journal article › Research › peer-review
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Butyrate protects pancreatic beta cells from cytokine-induced dysfunction
Research output: Contribution to journal › Journal article › Research › peer-review
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32
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Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells
Research output: Contribution to journal › Journal article › Research › peer-review
Published