Michael J. Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
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Detection and characterisation of radicals using electron paramagnetic resonance (EPR) spin trapping and related methods
Davies, Michael J., 2016, In: Methods. 109, p. 21-30 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
The oxidative environment and protein damage
Davies, Michael J., 17 Jan 2005, In: B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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EPR spin trapping of protein radicals
Davies, Michael J. & Hawkins, Clare Louise, 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mammalian heme peroxidases: from molecular mechanisms to health implications
Davies, Michael J., Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In: Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates
Davies, Michael J. & Hawkins, C. L., Dec 2000, In: Free Radical Research. 33, 6, p. 719-29 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Singlet oxygen-mediated damage to proteins and its consequences
Davies, Michael J., 6 Jun 2003, In: Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Free Radical Research origins
Davies, Michael J., Jan 2012, In: Free Radical Research. 46, 1, p. 1Research output: Contribution to journal › Journal article › Research
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Myeloperoxidase: Mechanisms, reactions and inhibition as a therapeutic strategy in inflammatory diseases
Davies, Michael J., 2021, In: Pharmacology and Therapeutics. 218, 23 p., 107685.Research output: Contribution to journal › Review › Research › peer-review
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Reactivity of Peroxidase-Derived Oxidants with Proteins, Glycoproteins and Proteoglycans
Davies, Michael J., 1 Jan 2021, Mammalian Heme Peroxidases: Diverse Roles in Health and Disease. CRC Press, p. 53-77Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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1,4-Anhydro-4-seleno-d-talitol (SeTal): a remarkable selenium-containing therapeutic molecule
Davies, Michael J. & Schiesser, C. H., 2019, In: New Journal of Chemistry. 43, 25, p. 9759-9765Research output: Contribution to journal › Review › Research › peer-review
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Peroxides and protein oxidation
Davies, Michael J., 1 Jan 2017, Hydrogen Peroxide Metabolism in Health and Disease. CRC Press, p. 101-124Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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In memoriam: Emeritus Professor Robin L. Willson
Davies, Michael J., Davies, K. J. A., Halliwell, B., Jackson, M. J., Mann, G. E., Poli, G., Radi, R., Riley, P. A., Sies, H., Ward, J. F., Wardman, P. & Willson, J., 2022, In: Free Radical Research. 56, 7-8, p. 572-576 5 p.Research output: Contribution to journal › Journal article › Research
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Tempus fugit horizontal ellipsis
Davies, Michael J., 2019, In: Free Radical Research. 53, 1, p. 1-1Research output: Contribution to journal › Editorial › Research › peer-review
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"What, where and how much? Key challenges in protein oxidation"
Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 165, Suppl. 1, p. 15-15 Suppl. 13-1.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cluster randomised controlled trial
Davies, Michael J., Heller, S., Skinner, Timothy, Campbell, M. J., Carey, M. E., Cradock, S., Dallosso, H. M., Daly, H., Doherty, Y., Eaton, S., Fox, C., Oliver, L., Rantell, K., Rayman, G. & Khunti, K., 1 Mar 2008, In: BMJ. 336, 7642, p. 491-495 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The DESMOND educational intervention
Davies, Michael J., Heller, S., Khunti, K. & Skinner, Timothy, 1 Mar 2008, In: Chronic Illness. 4, 1, p. 38-40 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Adduction reactions of alpha,beta-unsaturated aldehydes to proteins
Davies, Michael J., 2022, In: Toxicology Letters. 368, Suppl, p. S62-S62 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching
David Figueroa, J., Fuentes-Lemus, E., Dorta, E., Melin, V., Cortes-Rios, J., Faundez, M., Contreras, D., Denicola, A., Alvarez, B., Davies, Michael J. & Lopez-Alarcon, C., 2019, In: Redox Biology. 24, 9 p., 101207.Research output: Contribution to journal › Journal article › Research › peer-review
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Anthocyanin complex niosome gel accelerates oral wound healing: In vitro and clinical studies
Damrongrungruang, T., Paphangkorakit, J., Limsitthichaikoon, S., Khampaenjiraroch, B., Davies, Michael J., Sungthong, B. & Priprem, A., 2021, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 37, 14 p., 102423.Research output: Contribution to journal › Journal article › Research › peer-review
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Dityrosine, 3,4-dihydroxyphenylalanine (DOPA), and radical formation from tyrosine residues on milk proteins with globular and flexible structures as a result of riboflavin-mediated photo-oxidation
Dalsgaard, T. K., Nielsen, J. H., Brown, B. E., Stadler, N. & Davies, Michael J., 27 Jul 2011, In: Journal of Agricultural and Food Chemistry. 59, 14, p. 7939-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: The Microalbuminuria Education and Medication Optimisation (MEMO) study
Crasto, W., Jarvis, J., Khunti, K., Skinner, Timothy, Gray, L. J., Brela, J., Troughton, J., Daly, H., Lawrence, I. G., McNally, P. G., Carey, M. E. & Davies, Michael J., 1 Sep 2011, In: Diabetes Research and Clinical Practice. 93, 3, p. 328-336 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Myeloperoxidase Alters Lung Cancer Cell Function to Benefit Their Survival
Cosic-Mujkanovic, N., Valadez-Cosmes, P., Maitz, K., Lueger, A., Mihalic, Z. N., Runtsch, M. C., Kienzl, M., Davies, Michael J., Chuang, Christine, Heinemann, A., Schicho, R., Marsche, G. & Kargl, J., 2023, In: Antioxidants. 12, 8, 17 p., 1587.Research output: Contribution to journal › Journal article › Research › peer-review
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A hydrogen-donating monohydroxamate scavenges ferryl myoglobin radicals
Cooper, C. E., Green, E. S., Rice-Evans, C. A., Davies, Michael J. & Wrigglesworth, J. M., Apr 1994, In: Free Radical Research. 20, 4, p. 219-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-Derived Oxidants Rapidly and Efficiently Oxidise Protein Zinc-Thiol Clusters
Cook, N. L., Pattison, David & Davies, Michael J., 2012, In: Free Radical Biology and Medicine. 53, Supl. 2, p. S146 1 p., 355.Research output: Contribution to journal › Conference abstract in journal › Research
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The myeloperoxidase-derived oxidant hypothiocyanous acid inhibits protein tyrosine phosphatases via oxidation of key cysteine residues
Cook, N. L., Moeke, C. H., Fantoni, L. I., Pattison, D. I. & Davies, Michael J., 1 Jan 2016, In: Free Radical Biology & Medicine. 90, p. 195-205 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells
Cook, N. L., Viola, H. M., Sharov, V. S., Hool, L. C., Schöneich, C. & Davies, Michael J., 1 Mar 2012, In: Free Radical Biology & Medicine. 52, 5, p. 951-61 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants rapidly oxidize and disrupt zinc-cysteine/histidine clusters in proteins
Cook, N. L., Pattison, D. I. & Davies, Michael J., 1 Dec 2012, In: Free Radical Biology & Medicine. 53, 11, p. 2072-80 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel monohydroxamate drugs attenuate myocardial reperfusion-induced arrhythmias
Collis, C. S., Rice-Evans, C. & Davies, Michael J., Apr 1996, In: International Journal of Biochemistry & Cell Biology. 28, 4, p. 405-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidant-modified amylin fibrils and aggregates alter the inflammatory profile of multiple myeloid cell types, but are non-toxic to islet β cells
Clemen, R., Fuentes Lemus, Eduardo, Bekeschus, S. & Davies, Michael J., 2023, In: Redox Biology. 65, 14 p., 102835.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells
Chuang, Christine, Degendorfer, G., Hammer, A., Whitelock, J. M., Malle, E. & Davies, Michael J., 15 Apr 2014, In: Biochemical Journal. 459, 2, p. 313-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation and modification of extracellular matrix and its role in disease
Chuang, Christine, Degendorfer, G. & Davies, Michael J., Sep 2014, In: Free Radical Research. 48, 9, p. 970-89 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Protein-Derived Amino Acid Modification Products Present in Infant Formula on Metabolic Function, Oxidative Stress, and Intestinal Permeability in Cell Models
Chen, Z., Kondrashina, A., Greco, I., Gamon, Luke Francis, Lund, Marianne N., Giblin, L. & Davies, Michael J., 2019, In: Journal of Agricultural and Food Chemistry. 67, 19, p. 5634-5646Research output: Contribution to journal › Journal article › Research › peer-review
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Characterisation and quantification of protein oxidative modifications and amino acid racemisation in powdered infant milk formula
Chen, Z., Leinisch, F., Greco, I., Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael J., 2019, In: Free Radical Research. 53, 1, p. 68-81Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization and quantification of protein oxidative modifications and amino acid racemization in powdered infant milk formula: [Meeting Abstract]
Chen, Z., Leinisch, F., Greco, I., Zhang, W., Shu, N., Chuang, Christine, Lund, Marianne N. & Davies, Michael J., 2018, In: Free Radical Biology and Medicine. 120, Supplement 1, p. S47 1 p., P-8.Research output: Contribution to journal › Conference abstract in journal › Research
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The Use of Membrane Filtration to Increase Native Whey Proteins in Infant Formula
Chen, Y., Callanan, M., Shanahan, C., Tobin, J., Gamon, Luke Francis, Davies, Michael J., Giblin, L. & Brodkorb, A., Sep 2021, In: Dairy. 2, 4, p. 515-529Research output: Contribution to journal › Journal article › Research › peer-review
Hypobromous acid and bromamine production by neutrophils and modulation by superoxide
Chapman, A. L. P., Skaff, O., Senthilmohan, R., Kettle, A. J. & Davies, Michael J., 1 Feb 2009, In: Biochemical Journal. 417, 3, p. 773-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selenium-containing indolyl compounds: Kinetics of reaction with inflammation-associated oxidants and protective effect against oxidation of extracellular matrix proteins
Casaril, A. M., Ignasiak, M. T., Chuang, Christine, Vieira, B., Padilha, N. B., Carroll, L., Lenardão, E. J., Savegnago, L. & Davies, Michael J., Dec 2017, In: Free Radical Biology & Medicine. 113, p. 395-405 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Formation and detection of oxidant-generated tryptophan dimers in peptides and proteins
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael J., Dec 2017, In: Free Radical Biology & Medicine. 113, p. 132-142 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael J. & Hawkins, Clare Louise, 2017, In: Redox Biology. 12, p. 872-882 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interaction kinetics of selenium -containing compounds with oxidants
Carroll, L., Gardiner, K., Ignasiak, M., Holmehave, J., Shimodaira, S., Breitenbach, T., Iwaoka, M., Ogilby, P. R., Pattison, David & Davies, Michael J., 2020, In: Free Radical Biology and Medicine. 155, p. 58-68Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidant-induced glutathionylation at protein disulfide bonds
Carroll, L., Jiang, S., Irnstorfer, J., Beneyto, S., Ignasiak, M. T., Rasmussen, L. M., Rogowska-Wrzesinska, A. & Davies, Michael J., 20 Nov 2020, In: Free Radical Biology and Medicine. 160, p. 513-525 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Superoxide radicals react with peptide-derived tryptophan radicals with very high rate constants to give hydroperoxides as major products
Carroll, L., Pattison, D. I., Davies, J. B., Anderson, R. F., Lopez-Alarcon, C. & Davies, Michael J., Apr 2018, In: Free Radical Biology and Medicine. 118, p. 126-136Research output: Contribution to journal › Journal article › Research › peer-review
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Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage
Carroll, L., Pattison, D. I., Fu, S., Schiesser, C. H., Davies, Michael J. & Hawkins, Clare Louise, Jul 2015, In: Free Radical Biology & Medicine. 84, p. 279-288 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Carnosine and Carcinine Derivatives Rapidly React with Hypochlorous Acid to Form Chloramines and Dichloramines
Carroll, L., Karton, A., Radom, L., Davies, Michael J. & Pattison, D. I., 2019, In: Chemical Research in Toxicology. 32, 3, p. 513-525 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reaction of low-molecular-mass organoselenium compounds (and their sulphur analogues) with inflammation-associated oxidants
Carroll, L., Davies, Michael J. & Pattison, D. I., 2015, In: Free Radical Research. 49, 6, p. 750-767 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
Increasing capacity to deliver diabetes self-management education: Results of the DESMOND lay educator non-randomized controlled equivalence trial
Carey, M. E., Mandalia, P. K., Daly, H., Gray, L. J., Hale, R., Martin Stacey, L., Taub, N., Skinner, Timothy, Stone, M., Heller, S., Khunti, K. & Davies, Michael J., 1 Jan 2014, In: Diabetic Medicine. 31, 11, p. 1431-1438 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiple oxidative post-translational modifications of human glutamine synthetase mediate peroxynitrite-dependent enzyme inactivation and aggregation
Campolo, N., Mastrogiovanni, M., Mariotti, M., Issoglio, F. M., Estrin, D., Hägglund, Per Mårten, Grune, T., Davies, Michael J., Bartesaghi, S. & Radi, R., 2023, In: Journal of Biological Chemistry. 299, 3, 22 p., 102941.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorous acid-modified extracellular matrix contributes to the behavioral switching of human coronary artery smooth muscle cells
Cai, H., Chuang, Christine, Vanichkitrungruang, S., Hawkins, Clare Louise & Davies, Michael J., 2019, In: Free Radical Biology and Medicine. 134, p. 526-536Research output: Contribution to journal › Journal article › Research › peer-review
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Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification
Cai, H., Chuang, Christine, Hawkins, Clare Louise & Davies, Michael J., 2020, In: Scientific Reports. 13 p., 666.Research output: Contribution to journal › Journal article › Research › peer-review
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Modification of the extracellular matrix of the arterial wall by myeloperoxidase contributes to atherosclerosis: [Meeting Absract]
Cai, H., Chuang, Christine & Davies, Michael J., 2018, In: International Journal of Experimental Pathology. 99, 6, p. A24-A24Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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