Mette Rosenkilde

Mette Rosenkilde

Professor

Member of:

    ORCID: 0000-0001-9600-3254

    Publication year:
    All
    101 - 200 out of 272Page size: 100
    Sort by: Title
    1. Published

      Glucose-lowering effects and mechanisms of the bile acid-sequestering resin sevelamer

      Brønden, A., Mikkelsen, K., Sonne, D. P., Hansen, M., Våben, C., Gabe, M. N., Rosenkilde, Mette, Tremaroli, V., Wu, H., Bäckhed, F., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jul 2018, In: Diabetes, Obesity and Metabolism. 20, 7, p. 1623-1631

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Glycine: a long-sought novel ligand for GPR158

      Rosenkilde, Mette & Mathiesen, Jesper M., 2023, In: Trends in Pharmacological Sciences. 44, 8, p. 489-491

      Research output: Contribution to journal › Letter › Research › peer-review

    3. Published

      Gut Hormones and Their Effect on Bone Metabolism. Potential Drug Therapies in Future Osteoporosis Treatment

      Schiellerup, S. P., Skov-Jeppesen, Kirsa, Windeløv, Johanne Agerlin, Svane, M. S., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2019, In: Frontiers in Endocrinology. 10, 13 p., 75.

      Research output: Contribution to journal › Review › Research › peer-review

    4. Published

      High constitutive activity of a virus-encoded seven transmembrane receptor in the absence of the conserved DRY motif (Asp-Arg-Tyr) in transmembrane helix 3

      Rosenkilde, Mette, Kledal, T. N. & Schwartz, Thue W., 2005, In: Molecular Pharmacology. 68, 1, p. 11-9 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      High content screening for G protein-coupled receptors using cell-based protein translocation assays

      Grånäs, C., Lundholt, B. K., Heydorn, A., Linde, V., Pedersen, H., Krog-Jensen, C., Rosenkilde, Mette & Pagliaro, L., 2005, In: Combinatorial Chemistry & High Throughput Screening. 8, 4, p. 301-9 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1

      Torekov, S. S., Ma, L., Grarup, N., Hartmann, B., Hainerová, I. A., Kielgast, U., Kissow, H., Rosenkilde, M., Lebl, J., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Madsen, O. D., Wang, J., Linneberg, A., Madsbad, S., Holst, J. J., Hansen, T., Pedersen, O. & 1 others, GIANT Consortium, G. C., 2011, In: Diabetologia. 54, 11, p. 2820-31 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      How receptor mutagenesis may confirm or confuse receptor classification

      Schwartz, Thue W., Perlman, S., Rosenkilde, Mette & Hjorth, S. A., 1997, In: Annals of the New York Academy of Sciences. 817, p. 71-84

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor

      Gessier, F., Preuss, I., Yin, H., Rosenkilde, Mette, Laurent, S., Endres, R., Chen, Y. A., Marsilje, T. H., Seuwen, K., Nguyen, D. G. & Sailer, A. W., 24 Apr 2014, In: Journal of Medicinal Chemistry. 57, 8, p. 3358-68 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Identification and functional comparison of seven-transmembrane G-protein-coupled BILF1 receptors in recently discovered nonhuman primate lymphocryptoviruses

      Spiess, Katja, Fares, S., wbf943, wbf943, Hilgenberg, E., Jarvis, M. A., Ehlers, B. & Rosenkilde, Mette, Feb 2015, In: Journal of Virology. 89, 4, p. 2253-67 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Identification of a Salt Bridge That Is Functionally Important for Chemokine Receptor CXCR1 but not CXCR2

      Våbenø, J., Oliva-Santiago, M., Jørgensen, Astrid Sissel, Karlshøj, S. & Rosenkilde, Mette, 2023, In: ACS Pharmacology and Translational Science. 6, 8, p. 1120-1128 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Identification of a conserved chemokine receptor motif that enables ligand discrimination

      Larsen, Olav, van der Velden, W. J. C., Mavri, M., Schuermans, S., Rummel, P. C., Karlshøj, S., Gustavsson, Martin, Proost, P., Våbenø, J. & Rosenkilde, Mette, 2022, In: Science Signaling. 15, 724, eabg7042.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Identification of a novel site within G protein alpha subunits important for specificity of receptor-G protein interaction

      Heydorn, A., Ward, R. J., Jorgensen, R., Rosenkilde, Mette, Frimurer, T. M., Milligan, G. & Kostenis, E., 2004, In: Molecular Pharmacology. Vol. 66, no. 2, p. 250-9

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Identification of common mechanisms by which human and mouse cytomegalovirus seven-transmembrane receptor homologues contribute to in vivo phenotypes in a mouse model

      Farrell, H. E., Abraham, A. M., Cardin, R. D., Mølleskov-Jensen, A., Rosenkilde, Mette & Davis-Poynter, N., Apr 2013, In: Journal of Virology. 87, 7, p. 4112-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Importance of endogenous GLP-1 and GIP for postprandial glucose tolerance after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

      Hindso, M., Hedback, N., Moller, A., Svane, M. S., Martinussen, C., Jorgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Moller, K. N., 2021, In: Diabetologia. 64, SUPPL 1, p. 200-201 387.

      Research output: Contribution to journal › Conference abstract in journal › Research

    15. Published

      In vivo and in vitro degradation of peptide YY3-36 to inactive peptide YY3-34 in humans

      Toräng, S., Bojsen-Møller, K. N., Svane, M. S., Hartmann, Bolette, Rosenkilde, Mette, Madsbad, Sten & Holst, Jens Juul, 27 Jan 2016, In: A J P: Regulatory, Integrative and Comparative Physiology (Online). 310, 1, p. R866-R874 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats

      Baidassano, S., Gasbjerg, Lærke Smidt, Kizilkaya, Hüsün Sheyma, Rosenkilde, Mette, Holst, Jens Juul & Hartmann, Bolette, 2019, In: Frontiers in Endocrinology. 10, 11 p., 492.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor

      Rode, A. K. O., Buus, Terkild Brink, Mraz, Veronika, Al-Jaberi, F. A. H., Lopez, D. V., Ford, Shayne Lavondua, Hennen, S., Eliasen, I. P., Klewe, I. V., Gharehdaghi, L., Dragan, A., Rosenkilde, Mette, Woetmann, Anders , Skov, Lone, Ødum, Niels, Bonefeld, Charlotte Menne, Kongsbak-Wismann, Martin & Geisler, Carsten, 2022, In: Cells. 11, 16, 2587.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Influence of chain length on the activity of tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4)

      Baumann, M., Hussain, M. M., Henne, N., Garrote, D. M., Karlshoj, S., Fossen, T., Rosenkilde, Mette, Vabeno, J. & Haug, B. E., 15 Jan 2017, In: Bioorganic & Medicinal Chemistry. 25, 2, p. 646-657

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Inhibition of HIV Fusion by Small Molecule Agonists through Efficacy-Engineering of CXCR4

      Berg, Christian, Daugvilaite, V., Steen, A., Jørgensen, Astrid Sissel, Våbenø, J. & Rosenkilde, Mette, 20 Apr 2018, In: ACS chemical biology. 13, 4, p. 881-886 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Inhibition of human immunodeficiency virus replication by a dual CCR5/CXCR4 antagonist

      Princen, K., Hatse, S., Vermeire, K., Aquaro, S., De Clercq, E., Gerlach, L., Rosenkilde, Mette, Schwartz, Thue W., Skerlj, R., Bridger, G. & Schols, D., 2004, In: Journal of Virology. 78, 23, p. 12996-3006 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor

      Yuliantie, E., van der Velden, W. J. C., Labroska, V., Dai, A., Zhao, F., Darbalaei, S., Deganutti, G., Xu, T., Zhou, Q., Yang, D., Rosenkilde, Mette, Sexton, P. M., Wang, M. W. & Wootten, D., 2021, In: Biochemical Pharmacology. 192, 16 p., 114715.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Interaction of chemokines with their receptors--from initial chemokine binding to receptor activating steps

      Thiele, S. & Rosenkilde, Mette, 2014, In: Current Medicinal Chemistry. 21, 31, p. 3594-614 21 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Investigating GIPR (ant)agonism: A structural analysis of GIP and its receptor

      Smit, F. X., van der Velden, W. J. C., Kizilkaya, Hüsün Sheyma, Nørskov, A., Lückmann, Michael, Hansen, T. N., wbf943, wbf943, Qvotrup, K., Frimurer, Thomas Michael & Rosenkilde, Mette, 2021, In: Structure. 29, 7, p. 679-693.e6 21 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Kaposi sarcoma-associated herpes virus targets the lymphotactin receptor with both a broad spectrum antagonist vCCL2 and a highly selective and potent agonist vCCL3

      Lüttichau, H. R., Johnsen, A. H., Jurlander, J., Rosenkilde, Mette & Schwartz, Thue W., 2007, In: Journal of Biological Chemistry. 282, 24, p. 17794-805 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion

      Kuhre, Rune Ehrenreich, Modvig, Ida Marie, Jepsen, Sara Lind, Kizilkaya, Hüsün Sheyma, Bæch-Laursen, C., Smith, C. A., Reimann, F., Gribble, F. M., Rosenkilde, Mette & Holst, Jens Juul, 2021, In: Frontiers in Endocrinology. 12, 12 p., 690387.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Ligand Modulation of the Epstein-Barr Virus-induced Seven-transmembrane Receptor EBI2: IDENTIFICATION OF A POTENT AND EFFICACIOUS INVERSE AGONIST

      Benned-Jensen, T., Smethurst, C., Holst, Peter Johannes, Page, K. R., Sauls, H., Sivertsen, B. B., Schwartz, Thue W., Blanchard, A., Jepras, R. & Rosenkilde, Mette, 19 Aug 2011, In: Journal of Biological Chemistry. 286, p. 29292-29302 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Ligand binding and micro-switches in 7TM receptor structures

      Nygaard, R., Frimurer, T. M., Holst, Birgitte, Rosenkilde, Mette & Schwartz, Thue W., 2009, In: TIPS - Trends in Pharmacological Sciences. 30, 5, p. 249-59 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Ligand entry pathways control the chemical space recognized by GPR183

      Kjær, Viktoria Madeline Skovgaard, Stępniewski, T. M., Medel-Lacruz, B., Reinmuth, L., Ciba, Marija, Ulven, Elisabeth Rexen, Bonomi, M., Selent, J. & Rosenkilde, Mette, 2023, In: Chemical Science. 14, 39, p. 10671-10683

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Ligand-selective small molecule modulators of the constitutively active vGPCR US28

      Amarandi, R., Lückmann, Michael, Melynis, M., Jakobsen, M. H., Fallah, Z., Spiess, Katja, Hjortø, Gertrud Malene, Pui, A., Frimurer, Thomas Michael & Rosenkilde, Mette, 2018, In: European Journal of Medicinal Chemistry. 155, p. 244-254

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system

      Gadgaard, S., Windeløv, Johanne Agerlin, Schiellerup, S. P., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2023, In: Biomedicine and Pharmacotherapy. 160, 13 p., 114383.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Loss of Adgra3 causes obstructive azoospermia with high penetrance in male mice

      Nybo, Maja Lind, Kvam, J. M., Nielsen, J. E., Frederiksen, H., Spiess, Katja, Jensen, Kristian HR, Gadgaard, S., Walser, Anna Louise Silvia, Thomsen, J. S., Cowin, P., Juul, Anders, Jensen, M. B. & Rosenkilde, Mette, 2023, In: FASEB Journal. 37, 2, 13 p., 22781.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Loss of Function Glucose-Dependent Insulinotropic Polypeptide Receptor Variants Are Associated With Alterations in BMI, Bone Strength and Cardiovascular Outcomes

      Kizilkaya, Hüsün Sheyma, Sørensen, Kimmie Vestergaard, Kibsgaard, C. J., Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, wbf943, wbf943, Grarup, Niels & Rosenkilde, Mette, 2021, In: Frontiers in Cell and Developmental Biology. 9, 12 p., 749607.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Maintenance of cardiorespiratory fitness, body composition, and a physically active lifestyle after structured exercise interventions in individuals with overweight and obesity: A mixed-method follow-up study

      Quist, Jonas Salling, Winther, J., Friis, A. L., Gram, A. S., Blond, Martin Bæk, Rosenkilde, Mette, Jespersen, Astrid Pernille & Stallknecht, Bente Merete, 2022, In: Public Health in Practice. 4, 10 p., 100293.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Maintenance of improvements in fitness and fatness 1 year after a 3-month lifestyle intervention in overweight men

      Rosenkilde, Mette, Nordby, P. & Stallknecht, Bente Merete, Oct 2016, In: European Journal of Clinical Nutrition. 70, 10, p. 1212-1214 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Metal ion enhanced binding of AMD3100 to Asp262 in the CXCR4 receptor

      Gerlach, L. O., Jakobsen, J. S., Jensen, K. P., Rosenkilde, Mette, Skerlj, R. T., Ryde, U., Bridger, G. J. & Schwartz, Thue W., 2003, In: Biochemistry. 42, 3, p. 710-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Methods for Studying Endocytotic Pathways of Herpesvirus Encoded G Protein-Coupled Receptors

      Mavri, M., Spiess, Katja, Rosenkilde, Mette, Rutland, C. S., Vrecl, M. & Kubale, V., 2020, In: Molecules. 25, 23, 23 p., 5710.

      Research output: Contribution to journal › Review › Research › peer-review

    37. Published

      Microbiological exploitation of the chemokine system

      Holst, Peter Johannes & Rosenkilde, Mette, 2003, In: Microbes and Infection. 5, 2, p. 179-87 8 p.

      Research output: Contribution to journal › Review › Research

    38. Published

      Microbiological exploitation of the chemokine system

      Holst, Peter Johannes & Rosenkilde, Mette, 2003, In: Microbes and Infection. Vol. 2, p. 179-87

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Migration mediated by the oxysterol receptor GPR183 depends on arrestin coupling but not receptor internalization

      Kjær, Viktoria Madeline Skovgaard, Daugvilaite, V., Stepniewski, T. M., Madsen, C. M., Jørgensen, Astrid Sissel, Bhuskute, K. R., Inoue, A., Ulven, Trond, Benned-Jensen, T., Hjorth, Siv Annegrethe, Hjortø, Gertrud Malene, Moo, Ee Von, Selent, J. & Rosenkilde, Mette, 2023, In: Science Signaling. 16, 779, 13 p., eabl4283.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Modest human immunodeficiency virus coreceptor function of CXCR3 is strongly enhanced by mimicking the CXCR4 ligand binding pocket in the CXCR3 receptor

      Hatse, S., Huskens, D., Princen, K., Vermeire, K., Bridger, G. J., De Clercq, E., Rosenkilde, Mette, Schwartz, Thue W. & Schols, D., 2007, In: Journal of Virology. 81, 7, p. 3632-9 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors

      Thiele, S., Malmgaard-Clausen, M., Engel-Andreasen, J., Steen, A., Rummel, P. C., Nielsen, M. C., Gloriam, David E., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 27 Sep 2012, In: Journal of Medicinal Chemistry. 55, 18, p. 8164-77 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Molecular Mechanism of Action for Allosteric Modulators and Agonists in CC-chemokine Receptor 5 (CCR5)

      Karlshøj, S., Amarandi, R. M., Larsen, Olav, Daugvilaite, V., Steen, A., Brvar, M., Pui, A., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 23 Dec 2016, In: Journal of Biological Chemistry. 291, 52, p. 26860-26874

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Molecular Pharmacology of CXCR4 inhibition

      Steen, A. & Rosenkilde, Mette, 2012, Novel Developments in Stem Cell Mobilization : Focus on CXCR4. Fruehauf, S., Zeller, J. W. & Calandra, G. (eds.). Springer Science+Business Media, p. 23-35

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    44. Published

      Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)

      Benned-Jensen, T., Norn, C., Laurent, S., Madsen, C. M., Larsen, H. M., Arfelt, K. N., Wolf, R. M., Frimurer, Thomas Michael, Sailer, A. W. & Rosenkilde, Mette, 12 Oct 2012, In: The Journal of Biological Chemistry. 287, 42, p. 35470-83 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8

      Jensen, P. C., Nygaard, R., Thiele, S., Elder, A., Zhu, G., Kolbeck, R., Ghosh, S., Schwartz, Thue W. & Rosenkilde, Mette, 2007, In: Molecular Pharmacology. 72, 2, p. 327-40 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Molecular interactions of full-length and truncated GIP peptides with the GIP receptor - A comprehensive review

      Gabe, M. B. N., van der Velden, W. J. C., Smit, F. X., Gasbjerg, Lærke Smidt & Rosenkilde, Mette, 2020, In: Peptides. 125, 8 p., 170224.

      Research output: Contribution to journal › Review › Research › peer-review

    47. Published

      Molecular mechanism of 7TM receptor activation--a global toggle switch model

      Schwartz, Thue W., Frimurer, T. M., Holst, Birgitte, Rosenkilde, Mette & Elling, C. E., 2006, In: Annual Review of Pharmacology and Toxicology. 46, p. 481-519 38 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor: transfer of binding site to the CXCR3 receptor

      Rosenkilde, Mette, Gerlach, L., Jakobsen, J. S., Skerlj, R. T., Bridger, G. J. & Schwartz, Thue W., 2004, In: Journal of Biological Chemistry. 279, 4, p. 3033-41 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor: transfer of binding site to the CXCR3 receptor

      Rosenkilde, Mette, Gerlach, L., Jakobsen, J. S., Skerlj, R. T., Bridger, G. & Schwartz, Thue W., 2004, In: Journal of Biological Chemistry. VOl. 279, no. 4, p. 3033-41

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Molecular mechanism of action of monocyclam versus bicyclam non-peptide antagonists in the CXCR4 chemokine receptor

      Rosenkilde, Mette, Gerlach, L., Hatse, S., Skerlj, R. T., Schols, D., Bridger, G. J. & Schwartz, Thue W., 2007, In: Journal of Biological Chemistry. 282, 37, p. 27354-65 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity

      Rosenkilde, Mette, Benned-Jensen, T., Holst, Peter Johannes, Kledal, T. N., Lüttichau, H. R., Larsen, J. K., Christensen, Jan Pravsgaard, Schwartz, Thue W. & Andersen, H., 2006, In: Journal of Biological Chemistry. 281, 19, p. 13199-208 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Molecular properties and therapeutic targeting of the ebv-encoded receptor bilf1

      Knerr, J. M., Kledal, T. N. & Rosenkilde, Mette, 2021, In: Cancers. 13, 16, 26 p., 4079.

      Research output: Contribution to journal › Review › Research › peer-review

    53. Published

      Molecular requirements for inhibition of the chemokine receptor CCR8--probe-dependent allosteric interactions

      Rummel, P. C., Arfelt, K. N., Baumann, L., Jenkins, T. J., Thiele, S., Lüttichau, H. R., Johnsen, A., Pease, J., Ghosh, S., Kolbeck, R. & Rosenkilde, Mette, Nov 2012, In: British Journal of Pharmacology. 167, 6, p. 1206-17 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Multiple Targets for Oxysterols in Their Regulation of the Immune System

      Reinmuth, L., Hsiao, C. C., Hamann, J., Rosenkilde, Mette & Mackrill, J., 2021, In: Cells. 10, 8, 27 p., 2078.

      Research output: Contribution to journal › Review › Research › peer-review

    55. Published

      Multistep Continuous-Flow Synthesis in Medicinal Chemistry: Discovery and Preliminary Structure-Activity Relationships of CCR8 Ligands

      Petersen, T. P., Mirsharghi, S., Rummel, P. C., Thiele, S., Rosenkilde, Mette, Ritzén, A. & Ulven, Trond, 8 Jul 2013, In: Chemistry: A European Journal. 19, 28, p. 9343-50 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Mutational Landscape of the Proglucagon-Derived Peptides

      Lindquist, Peter, Madsen, Jakob Sture, Bräuner, Hans, Rosenkilde, Mette & Hauser, Alexander Sebastian, 2021, In: Frontiers in Endocrinology. 12, 14 p., 698511.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry

      Hatse, S., Princen, K., Vermeire, K., Gerlach, L., Rosenkilde, Mette, Schwartz, Thue W., Bridger, G., De Clercq, E. & Schols, D., 2003, In: FEBS Letters. 546, 2-3, p. 300-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Published

      N- and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor

      Hansen, L. S., wbf943, wbf943, Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 826-838 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction

      Gabe, M. B. N., Gasbjerg, Lærke Smidt, Gadgaard, S., Lindquist, Peter, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4473-4485

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Natural agonist enhancing bis-His zinc-site in transmembrane segment V of the tachykinin NK3 receptor

      Rosenkilde, Mette, Lucibello, M., Holst, Birgitte & Schwartz, Thue W., 1998, In: FEBS Letters. 439, 1-2, p. 35-40 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      Natural carboxyterminal truncation of human CXCL10 attenuates glycosaminoglycan binding, CXCR3A signaling and lymphocyte chemotaxis, while retaining angiostatic activity

      Dillemans, L., Yu, K., De Zutter, A., Noppen, S., Gouwy, M., Berghmans, N., Verhallen, L., De Bondt, M., Vanbrabant, L., Brusselmans, S., Martens, E., Schols, D., Verschueren, P., Rosenkilde, Mette, Marques, P. E., Struyf, S. & Proost, P., 2024, In: Cell Communication and Signaling. 22, 1, 23 p., 94.

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo

      Janssens, R., Mortier, A., Boff, D., Vanheule, V., Gouwy, M., Franck, C., Larsen, Olav, Rosenkilde, Mette, Damme, J. V., Amaral, F. A., Teixeira, M. M., Struyf, S. & Proost, P., 2016, In: OncoTarget. 7, 38, p. 62439-62459 21 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism

      Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Esser, N., Mongovin, S., Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Ceutz, F. R., Terzic, D., Mark, P. D., Plomgaard, Peter Stendahl, Goetze, Jens P. , Goossens, G. H., Blaak, E. E., Deacon, Carolyn F., Rosenkilde, Mette, Zraika, S., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Research. 5, 9, 15 p., bvab084.

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. Published

      Neprilysin inhibition increases plasma glucagon concentrations in humans with possible implications for hepatic amino acid metabolism

      Liver-Alpha-Cell Axis Grp, L. A. G., 2020, In: Diabetologia. 63, SUPPL 1, p. S72-S72 1 p., 144.

      Research output: Contribution to journal › Conference abstract in journal › Research

    65. Published

      Neuromedin U Does Not Act as a Decretin in Rats

      Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, Ida Marie, Mandrup-Poulsen, Thomas, Albrechtsen, Reidar, Rosenkilde, Mette, Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, In: Cell Metabolism. 29, 3, p. 719-726.e1-e5 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. Published

      Novel Chemokine-Based Immunotoxins for Potent and Selective Targeting of Cytomegalovirus Infected Cells

      Spiess, Katja, Jeppesen, Mads Gravers, Malmgaard-Clausen, M., Krzywkowski, K., Kledal, T. N. & Rosenkilde, Mette, 2017, In: Journal of Immunology Research. 2017, 12 p., 4069260.

      Research output: Contribution to journal › Journal article › Research › peer-review

    67. Published

      Oleoyl-lysophosphatidylinositol enhances glucagon-like peptide-1 secretion from enteroendocrine L-cells through GPR119

      Arifin, S. A., Paternoster, S., Carlessi, R., Casari, I., Ekberg, J. H., Maffucci, T., Newsholme, P., Rosenkilde, Mette & Falasca, M., 2018, In: B B A - Molecular and Cell Biology of Lipids. 1863, 9, p. 1132-1141

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. Published

      Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats

      Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. Published

      Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor

      Hassing, H. A., Engelstoft, M. S., Sichlau, R. M., Madsen, A. N., Rehfeld, Jens Frederik, Pedersen, Jens, Jones, R. M., Holst, Jens Juul, Schwartz, Thue W., Rosenkilde, Mette & Hansen, Harald S., 2016, In: BioFactors. 42, 6, p. 665-673

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      Oxysterol-EBI2 signaling in immune regulation and viral infection

      Daugvilaite, V., Arfelt, K. N., Benned-Jensen, T., Sailer, A. W. & Rosenkilde, Mette, Jul 2014, In: European Journal of Immunology. 44, 7, p. 1904-12 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. Published

      Partial functional complementation between human and mouse cytomegalovirus chemokine receptor homologues

      Farrell, H. E., Abraham, A. M., Cardin, R. D., wbf943, wbf943, Rosenkilde, Mette, Spiess, Katja, Jensen, T. H., Kledal, T. N. & Davis-Poynter, N., Jun 2011, In: Journal of Virology. 85, 12, p. 6091-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    72. Published

      Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis

      Mavri, M., Glišić, S., Senćanski, M., Vrecl, M., Rosenkilde, Mette, Spiess, Katja & Kubale, V., 2023, In: Cellular and Molecular Biology Letters. 28, 1, 19 p., 14.

      Research output: Contribution to journal › Journal article › Research › peer-review

    73. Published

      Peroxynitrite Exposure of CXCL12 Impairs Monocyte, Lymphocyte and Endothelial Cell Chemotaxis, Lymphocyte Extravasation in vivo and Anti-HIV-1 Activity

      Janssens, R., Boff, D., Ruytinx, P., Mortier, A., Vanheule, V., Larsen, Olav, Daugvilaite, V., Rosenkilde, Mette, Noppen, S., Liekens, S., Schols, D., De Meester, I., Opdenakker, G., Struyf, S., Teixeira, M. M., Amaral, F. A. & Proost, P., 2018, In: Frontiers in Immunology. 9, p. 1933

      Research output: Contribution to journal › Journal article › Research › peer-review

    74. Published

      Perspective: Implications of Ligand-Receptor Binding Kinetics for Therapeutic Targeting of G Protein-Coupled Receptors

      van der Velden, W. J. C., Heitman, L. H. & Rosenkilde, Mette, 2020, In: ACS Pharmacology & Translational Science. 3, 2, p. 179-189 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    75. Published

      Pharmacokinetics of high-dose intravenous melatonin in humans

      Andersen, Lars Peter Kloster, Werner, M. U., Rosenkilde, Mette, Fenger, A. Q., Petersen, M. C., Rosenberg, Jacob & Gögenur, Ismail, Mar 2016, In: Journal of Clinical Pharmacology. 56, 3, p. 324-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    76. Published

      Pharmacokinetics of oral and intravenous melatonin in healthy volunteers

      Andersen, Lars Peter Kloster, Werner, M. U., Rosenkilde, Mette, Harpsøe, N. G., Fuglsang, H., Rosenberg, Jacob & Gögenur, Ismail, 2016, In: BMC Pharmacology and Toxicology. 17, p. 1-5 5 p., 8.

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Published

      Pharmacological and structure-activity relationship studies of oleoyl-lysophosphatidylinositol synthetic mimetics

      Paternoster, S., Simpson, P. V., Kokh, E., Kizilkaya, Hüsün Sheyma, Rosenkilde, Mette, Mancera, R. L., Keating, D. J., Massi, M. & Falasca, M., 2021, In: Pharmacological Research. 172, 105822.

      Research output: Contribution to journal › Journal article › Research › peer-review

    78. Published

      Phorbol esters and SDF-1 induce rapid endocytosis and down-modulation of the chemokine receptor CXCR4

      Signoret, N., Oldridge, J., Pelchen-Matthews, A., Klasse, P. J., Tran, T., Brass, L. F., Rosenkilde, Mette, Schwartz, Thue W., Luther, M. A., Wells, T. N. C., Hoxie, J. A. & March, M., 1997, In: Journal of Cell Biology. 139, no. 3, p. 651-664

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. Published

      Physiology of the Incretin Hormones, GIP and GLP-1-Regulation of Release and Posttranslational Modifications

      Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Rosenkilde, Mette & Deacon, Carolyn F., 2019, In: Comprehensive Physiology. 9, 4, p. 1339-1381

      Research output: Contribution to journal › Journal article › Research › peer-review

    80. Published

      Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects

      Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. Published

      Positive versus negative modulation of different endogenous chemokines for CC-chemokine receptor 1 by small molecule agonists through allosteric versus orthosteric binding

      Jensen, P. C., Thiele, S., Ulven, Trond, Schwartz, Thue W. & Rosenkilde, Mette, 17 Jun 2008, In: Journal of Biological Chemistry. 283, 34, p. 23121-23128 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    82. Published

      Positive versus negative modulation of different endogenous chemokines for CC-chemokine receptor 1 by small molecule agonists through allosteric versus orthosteric binding

      Jensen, P. C., Thiele, S., Ulven, T., Schwartz, Thue W. & Rosenkilde, Mette, 2008, In: Journal of Biological Chemistry. 283, 34, p. 23121-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. Published

      Post-infection treatment with the E protein inhibitor BIT225 reduces disease severity and increases survival of K18-hACE2 transgenic mice infected with a lethal dose of SARS-CoV-2

      Ewart, G., Bobardt, M., Bentzen, Bo Hjorth, Yan, Y., Thomson, A., Klumpp, K., Becker, S., Rosenkilde, Mette, Miller, M. & Gallay, P., 2023, In: PLoS Pathogens. 19, 8 August, 20 p., e1011328.

      Research output: Contribution to journal › Journal article › Research › peer-review

    84. Published

      Potency of ligands correlates with affinity measured against agonist and inverse agonists but not against neutral ligand in constitutively active chemokine receptor

      Rosenkilde, Mette & Schwartz, Thue W., 2000, In: Molecular Pharmacology. 57, no. 3, p. 602-9

      Research output: Contribution to journal › Journal article › Research › peer-review

    85. Published

      Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist

      Simmons, G., Clapham, P. R., Picard, L., Offord, R. E., Rosenkilde, Mette, Schwartz, Thue W., Buser, R., Weels, T. N. C. & Proudfoot, A., 1997, In: Kexue (Shanghai). 276, p. 276-279

      Research output: Contribution to journal › Journal article › Research › peer-review

    86. Published

      Probing Biased Signaling in Chemokine Receptors

      Amarandi, R. M., Hjortø, Gertrud Malene, Rosenkilde, Mette & Karlshøj, S., 2016, Methods in Enzymology. Academic Press, Vol. 570. p. 155-186 32 p. (Methods in Enzymology, Vol. 570).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    87. Published

      Probing the Molecular Interactions between CXC Chemokine Receptor 4 (CXCR4) and an Arginine-Based Tripeptidomimetic Antagonist (KRH-1636)

      Zachariassen, Z. G., Karlshøj, S., Haug, B. E., Rosenkilde, Mette & Vabeno, J., 22 Oct 2015, In: Journal of Medicinal Chemistry. 58, 20, p. 8141-8153 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. Published

      Progress toward rationally designed small-molecule peptide and peptidomimetic CXCR4 antagonists

      Vabeno, J., Haug, B. E. & Rosenkilde, Mette, Jul 2015, In: Future Medicinal Chemistry. 7, 10, p. 1261-1283 23 p.

      Research output: Contribution to journal › Review › Research › peer-review

    89. Published

      Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor

      Ugleholdt, Randi Kjærsgaard, Poulsen, M. H., Holst, Peter Johannes, Irminger, J., Orskov, C., Pedersen, Jens, Rosenkilde, Mette, Zhu, X., Steiner, D. F. & Holst, Jens Juul, 2006, In: Journal of Biological Chemistry. 281, 16, p. 11050-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    90. Published

      Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes

      Melchiorsen, Josefine Ulrikke, Sørensen, Kimmie Vestergaard, Bork-Jensen, J., Kizilkaya, Hüsün Sheyma, Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, Rungby, Jørgen, Sørensen, H. T., Vaag, Allan, Nielsen, J. S., Pedersen, Oluf Borbye, Linneberg, Allan René, Hartmann, Bolette, Gjesing, A. P., Holst, Jens Juul, Hansen, Torben, Rosenkilde, Mette & Grarup, Niels, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2821–2833 38 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    91. Published

      Rat cytomegalovirus-encoded γ-chemokine vXCL1 is a highly adapted, species-specific agonist for rat XCR1-positive dendritic cells

      Bauer, A., Madela, J., Berg, Christian, Daugvilaite, V., Gurka, S., Mages, H. W., Kroczek, R. A., Rosenkilde, Mette & Voigt, S., 2020, In: Journal of Cell Science. 133, 5, 11 p., jcs236190.

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      Rational design of conformationally constrained cyclopentapeptide antagonists for C-x-C chemokine receptor 4 (CXCR4)

      Mungalpara, J., Thiele, S., Eriksen, Ø., Eksteen, J., Rosenkilde, Mette & Våbenø, J., 9 Oct 2012, In: Journal of Medicinal Chemistry. 55, 22, p. 10287-10291 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    93. Published

      Rationally designed chemokine-based toxin targeting the viral G protein-coupled receptor US28 potently inhibits cytomegalovirus infection in vivo

      Spiess, Katja, Jeppesen, M. G., Malmgaard-Clausen, M., Krzywkowski, K., Dulal, K., Cheng, T., Hjortø, Gertrud Malene, Larsen, Olav, Burg, J. S., Jarvis, M. A., Garcia, K. C., Zhu, H., Kledal, T. N. & Rosenkilde, Mette, Jul 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 27, p. 8427-8432 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Published

      Re-routing GPR56 signalling using Gα12/13 G protein chimeras

      Faas, Felix, Nørskov, Amalie, Holst, Peter Johannes, Andersson, A. M., Qvortrup, K., Mathiasen, Signe & Rosenkilde, Mette, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 378-389

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. Published

      Recent advances of GIP and future horizons

      Holst, Jens Juul & Rosenkilde, Mette, 2020, In: Peptides. 125, 6 p., 170230.

      Research output: Contribution to journal › Review › Research › peer-review

    96. Published

      Reply to: How Many SARS-CoV-2 "Viroporins" Are Really Ion Channels? [Inkl. Correction]

      Toft-Bertelsen, Trine Lisberg, Jeppesen, Mads Gravers, Landbrug, A., Mujezinovic, A., Bentzen, Bo Hjorth, Kledal, T. N. & Rosenkilde, Mette, 2022, In: Communications Biology . 5, 1, 1 p., 860.

      Research output: Contribution to journal › Letter › Research › peer-review

    97. Published

      Reversed binding of a small molecule ligand in homologous chemokine receptors - differential role of extracellular loop 2

      Jensen, P. C., Thiele, S., Steen, A., Elder, A., Kolbeck, R., Ghosh, S., Frimurer, Thomas Michael & Rosenkilde, Mette, May 2012, In: British Journal of Pharmacology. 166, 1, p. 258-75 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    98. Published

      Reversed binding of a small molecule ligand in homologous chemokine receptors – differential role of extracellular loop 2.

      Rummel, P. C., Thiele, S., Steen, A. M. F., Elder, A., Kolbech, R., Ghosh, S., Frimurer, Thomas Michael & Rosenkilde, Mette, 2011, In: British Journal of Pharmacology. 166

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Published

      Role of Conserved Disulfide Bridges and Aromatic Residues in Extracellular Loop 2 of Chemokine Receptor CCR8 for Chemokine and Small Molecule Binding

      Barington, L., Rummel, P. C., Lückmann, Michael, Pihl, H., Larsen, Olav, Daugvilaite, V., Johnsen, A. H., Frimurer, Thomas Michael, Karlshøj, S. & Rosenkilde, Mette, 19 May 2016, In: The Journal of Biological Chemistry. 291, 31, p. 16208-16220

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Published

      Selective Allosteric Modulation of N-Terminally Cleaved, but Not Full Length CCL3 in CCR1

      Larsen, Olav, Lückmann, Michael, van der Velden, W. J. C., Oliva-Santiago, M., Brvar, M., Ulven, Trond, Frimurer, Thomas Michael, Karlshøj, S. & Rosenkilde, Mette, 2019, In: ACS Pharmacology & Translational Science. 2, 6, p. 429-441 13 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    Previous 1 2 3 Next

    ID: 3361