Jens Juul Holst

Jens Juul Holst

Professor


  1. 2013
  2. Published

    Reduction in cardiovascular risk factors and insulin dose, but no beta-cell regeneration 1 year after Roux-en-Y gastric bypass in an obese patient with type 1 diabetes: a case report

    Dirksen, C., Jacobsen, S. H., Bojsen-Møller, K. N., Jørgensen, N. B., Naver, L. S., Hvolris, L. E., Worm, Dorte, Madsbad, Sten, Holst, Jens Juul & Hansen, D. L., 7 Dec 2013, In: Obesity Research & Clinical Practice. 7, 4, p. e269-74 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Appetite regulation in overweight, sedentary men after different amounts of endurance exercise: a randomized controlled trial

    Larsen, M. R., Reichkendler, M. H., Auerbach, P., Toräng, S., Gram, A. S., Ploug, Thorkil, Holst, Jens Juul, Sjödin, Anders Mikael & Stallknecht, Bente Merete, Dec 2013, In: Journal of Applied Physiology. 115, 11, p. 1599-1609 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Bile acids induce glucagon-like peptide 2 secretion with limited effects on intestinal adaptation in early weaned pigs

    Ipharraguerre, I. R., Tedó, G., Menoyo, D., de Diego Cabero, N., Holst, Jens Juul, Nofrarías, M., Mereu, A. & Burrin, D. G., Dec 2013, In: Journal of Nutrition. 143, 12, p. 1899-905 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Enteroendocrine secretion of gut hormones in diabetes, obesity and after bariatric surgery

    Holst, Jens Juul, Dec 2013, In: Current Opinion in Pharmacology. 13, 6, p. 983-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Evidence for paracrine/autocrine regulation of GLP-1-producing cells

    Kappe, C., Zhang, Q., Holst, Jens Juul, Nyström, T. & Sjöholm, A., 15 Nov 2013, In: A J P: Cell Physiology (Online). 305, 10, p. C1041-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Gut microbiota may have influence on glucose and lipid metabolism.

    Mikkelsen, K. H., Nielsen, M. F., Tvede, M., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 11 Nov 2013, In: Ugeskrift for Laeger. 175, 46, p. 2785-2788 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Normal physical activity obliterates the deleterious effects of high-caloric intake

    Krogh-Madsen, Rikke, Pedersen, M., Solomon, T., Knudsen, S. H., Hansen, L. S., Karstoft, K., Lehrskov-Schmidt, L., Pedersen, K. K., Thomsen, C., Holst, Jens Juul & Pedersen, Bente Klarlund, 7 Nov 2013, In: Journal of Applied Physiology. 116, 3, p. 231-239 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males

    Lund, M. T., Taudorf, L., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, 1 Nov 2013, In: European Journal of Applied Physiology. 113, 11, p. 2737-47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Long-term effects of bariatric surgery on meal disposal and β-cell function in diabetic and nondiabetic patients

    Camastra, S., Muscelli, E., Gastaldelli, A., Holst, Jens Juul, Astiarraga, B., Baldi, S., Nannipieri, M., Ciociaro, D., Anselmino, M., Mari, A. & Ferrannini, E., Nov 2013, In: Diabetes. 62, 11, p. 3709-17 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A pilot study examining the relationship among Crohn disease activity, glucagon-like peptide-2 signalling and intestinal function in pediatric patients

    Sigalet, D. L., Kravarusic, D., Butzner, D., Hartmann, Bolette, Holst, Jens Juul & Meddings, J., Oct 2013, In: Canadian Journal of Gastroenterology. 27, 10, p. 587-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety

    Deacon, Carolyn F. & Holst, Jens Juul, Oct 2013, In: Expert Opinion on Pharmacotherapy. 14, 15, p. 2047-58 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Effects of gastric bypass surgery on glucose absorption and metabolism during a mixed meal in glucose-tolerant individuals

    Jacobsen, S. H., Bojsen-Møller, K. N., Dirksen, C., Jørgensen, N. B., Clausen, T. R., Wulff, B. S., Kristiansen, V. B., Worm, Dorte, Hansen, D. L., Holst, Jens Juul, van Hall, Gerrit & Madsbad, Sten, Oct 2013, In: Diabetologia. 56, 10, p. 2250-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Preserved GLP-1 and exaggerated GIP secretion in type 2 diabetes and relationships with triglycerides and ALT

    Alssema, M., Rijkelijkhuizen, J. M., Holst, Jens Juul, Teerlink, T., Scheffer, P. G., Eekhoff, E. M. W., Gastaldelli, A., Mari, A., Hart, L. M., Nijpels, G. & Dekker, J. M., Oct 2013, In: European Journal of Endocrinology. 169, 4, p. 421-30 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Secretion of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes: systematic review and meta-analysis of clinical studies

    Calanna, S., Christensen, Mikkel Bring, Holst, Jens Juul, Laferrère, B., Gluud, Lise Lotte, Vilsbøll, T. & Knop, Filip Krag, Oct 2013, In: Diabetes Care. 36, 10, p. 3346-52 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Incretin hormones and the satiation signal

    Holst, Jens Juul, Sep 2013, In: International journal of obesity (2005). 37, 9, p. 1161-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Pancreatic safety of GLP-1-based therapeutic agents: further insights from rodent studies?

    Holst, Jens Juul, Sep 2013, In: Diabetologia. 56, 9, p. 1869-72 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effect of tumor necrosis factor-alpha infusion on the incretin effect in healthy volunteers

    Nielsen, S. T., Lehrskov-Schmidt, L., Krogh-Madsen, R., Solomon, T., Lehrskov-Schmidt, L., Holst, Jens Juul & Møller, K., 31 Jul 2013, In: Diabetes - Metabolism: Research and Reviews (Online). 29, 8, p. 655-663 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Molecular-scale simulation of electroluminescence in a multilayer white organic light-emitting diode

    Mesta, M., Carvelli, M., de Vries, R. J., van Eersel, H., van der Holst, J. J. M., Schober, M., Furno, M., Lüssem, B., Leo, K., Loebl, P., Coehoorn, R., Bobbert, P. A. & Holst, Jens Juul, Jul 2013, In: Nature Materials. 12, 7, p. 652-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    A dose-equivalent comparison of the effects of continuous subcutaneous glucagon-like peptide 2 (GLP-2) infusions versus meal related GLP-2 injections in the treatment of short bowel syndrome (SBS) patients

    Naimi, R. M., Madsen, K. B., Askov-Hansen, C., Brandt, C. F., Hartmann, Bolette, Holst, Jens Juul, Mortensen, P. B. & Jeppesen, Palle Bekker, 10 Jun 2013, In: Regulatory Peptides. 184, 10, p. 47-53 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Acute effects of continuous infusions of glucagon-like peptide (GLP)-1, GLP-2 and the combination (GLP-1+GLP-2) on intestinal absorption in short bowel syndrome (SBS) patients. A placebo-controlled study

    Madsen, K. B., Askov-Hansen, C., Naimi, R. M., Brandt, C. F., Hartmann, Bolette, Holst, Jens Juul, Mortensen, P. B. & Jeppesen, Palle Bekker, 10 Jun 2013, In: Regulatory Peptides. 184, 10, p. 30-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendal, C., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 23 May 2013, In: European Journal of Endocrinology. 169, p. 187-201 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway

    't Hart, L. M., Fritsche, A., Nijpels, G., van Leeuwen, N., Donnelly, L. A., Dekker, J. M., Alssema, M., Fadista, J., Carlotti, F., Gjesing, A. P., Palmer, C. N. A., van Haeften, T. W., Herzberg-Schäfer, S. A., Simonis-Bik, A. M. C., Houwing-Duistermaat, J. J., Helmer, Q., Deelen, J., Guigas, B., Hansen, T., Machicao, F. & 14 others, Willemsen, G., Heine, R. J., Kramer, M., Holst, Jens Juul, de Koning, E. J. P., Häring, H., Pedersen, Oluf Borbye, Groop, L., de Geus, E. J. C., Slagboom, P. E., Boomsma, D. I., Eekhoff, E. M. W., Pearson, E. R. & Diamant, M., 14 May 2013, In: Diabetes. 62, 9, p. 3275-3281 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Thirty days of resveratrol supplementation does not affect postprandial incretin hormone responses, but suppresses postprandial glucagon in obese subjects

    Knop, Filip Krag, Konings, E., Timmers, S., Schrauwen, P., Holst, Jens Juul & Blaak, E. E., 11 May 2013, In: Diabetic Medicine. 30, 10, p. 1214-1218 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The exaggerated glucagon-like peptide-1 response is important for the improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes

    Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Jacobsen, S. H., Worm, Dorte, Hansen, D. L., Kristiansen, V. B., Naver, L., Madsbad, Sten & Holst, Jens Juul, 6 May 2013, In: Diabetes. 62, 9, p. 3044-3052 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Gastrointestinal factors contribute to glucometabolic disturbances in nondiabetic patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, May 2013, In: Kidney International. 83, 5, p. 915-23 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Secretion of glucagon-like peptide-1 in patients with type 2 diabetes mellitus: systematic review and meta-analyses of clinical studies

    Calanna, S., Christensen, M., Holst, Jens Juul, Laferrère, B., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, May 2013, In: Diabetologia. 56, 5, p. 965-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded, parallel intervention study

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 26 Apr 2013, In: B M J Open. 3, 4, p. 1-10 11 p., e002764.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Increased Hepatic Insulin Clearance After Roux-en-Y Gastric Bypass

    Bojsen-Møller, K. N., Dirksen, C., Jørgensen, N. B., Jacobsen, S. H., Hansen, D. L., Worm, Dorte, Naver, L., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 22 Apr 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 6, p. E1066-E1071 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Early growth and postprandial appetite regulatory hormone responses

    Perälä, M., Kajantie, E., Valsta, L. M., Holst, Jens Juul, Leiviskä, J. & Eriksson, J. G., 19 Apr 2013, In: British Journal of Nutrition. 110, 09, p. 1-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendahl, C., Vilsbøll, Tina, Knop, Filip Krag & Holst, Jens Juul, 18 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, p. G1117-G1127 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Influence of erythropoietin on cognitive performance during experimental hypoglycemia in patients with type 1 diabetes mellitus: A Randomized Cross-Over Trial

    Kristensen, Peter Lommer, Pedersen-Bjergaard, Ulrik, Kjær, T. W., Olsen, N. V., Dela, Flemming, Holst, Jens Juul, Faber, Jens, Tarnow, L. & Thorsteinsson, B., 5 Apr 2013, In: P L o S One. 8, 4, p. 1-8 8 p., e59672.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Regulation of urea synthesis during the acute-phase response in rats

    Thomsen, K. L., Jessen, N., Møller, A. B., Aagaard, N. K., Grønbæk, H., Holst, Jens Juul & Vilstrup, H., 1 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 7, p. G680-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Fast pouch emptying, delayed small intestinal transit, and exaggerated gut hormone responses after Roux-en-Y gastric bypass

    Dirksen, C., Damgaard, Morten, Bojsen-Møller, K. N., Jørgensen, N. B., Kielgast, U., Jacobsen, S. H., Naver, L. S., Worm, Dorte, Holst, Jens Juul, Madsbad, Sten, Hansen, D. L. & Madsen, J. L., Apr 2013, In: Neurogastroenterology and Motility. 25, 4, p. 346-e255 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Glucagon-like peptide-1 (GLP-1): effect on kidney hemodynamics and renin-angiotensin-aldosterone system in healthy men

    Skov, J., Dejgaard, A., Frøkiær, J., Holst, Jens Juul, Jonassen, Thomas, Rittig, S. & Christiansen, J. S., Apr 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 4, p. E664-71 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells

    Kappe, C., Patrone, C., Holst, Jens Juul, Zhang, Q. & Sjöholm, A., Mar 2013, In: Journal of Gastroenterology. 48, 3, p. 322-32 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass

    Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Jacobsen, S. H., Clausen, T. R., Worm, Dorte, Hartmann, Bolette, Rehfeld, Jens Frederik, Damgaard, Morten, Madsen, J. L., Madsbad, Sten, Holst, Jens Juul & Hansen, D. L., 19 Feb 2013, In: International Journal of Obesity. 37, p. 1452-1459 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Postprandial gut hormone responses and glucose metabolism in cholecystectomized patients

    Sonne, D. P., Hare, K. J., Martens, P., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 15 Feb 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 4, p. G413-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Is there a place for incretin therapies in obesity and prediabetes?

    Holst, Jens Juul & Deacon, Carolyn F., 13 Feb 2013, In: Trends in Endocrinology and Metabolism. 24, 3, p. 145-152 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Reduced postprandial GLP-1 responses in women with gestational diabetes mellitus

    Bonde, L., Vilsbøll, Tina, Nielsen, T., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Larsen, S. & Knop, Filip Krag, 13 Feb 2013, In: Diabetes, Obesity and Metabolism. 15, 8, p. 713-720 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Effect of glucagon-like peptide-2 exposure on bone resorption: Effectiveness of high concentration versus prolonged exposure

    Askov-Hansen, C., Jeppesen, Palle Bekker, Lund, P., Hartmann, Bolette, Holst, Jens Juul & Henriksen, D. B., 10 Feb 2013, In: Regulatory Peptides. 181, p. 4-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    The C-terminal extension of exendin-4 provides additional metabolic stability when added to GLP-1, while there is minimal effect of truncating exendin-4 in anaesthetized pigs

    Simonsen, L., Holst, Jens Juul, Madsen, K. & Deacon, Carolyn F., 10 Feb 2013, In: Regulatory Peptides. 181, 10, p. 17-21 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Removal of Duodenum Elicits GLP-1 Secretion

    Muscogiuri, G., Mezza, T., Prioletta, A., Sorice, G. P., Clemente, G., Sarno, G., Nuzzo, G., Pontecorvi, A., Holst, Jens Juul & Giaccari, A., 7 Feb 2013, In: Diabetes Care. 36, 6, p. 1641-1646 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Increased expression of glucagon-like peptide-1 receptors in psoriasis plaques

    Faurschou, A., Pedersen, Jens, Gyldenløve, M., Poulsen, Steen Seier, Holst, Jens Juul, Thyssen, Jacob Pontoppidan, Zachariae, Claus, Vilsbøll, Tina, Skov, Lone & Knop, Filip Krag, Feb 2013, In: Experimental Dermatology. 22, 2, p. 150-2 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    GLP-2 Delays But Does Not Prevent the Onset of Necrotizing Enterocolitis in Preterm Pigs

    Benight, N. M., Stoll, B., Olutoye, O. O., Holst, Jens Juul & Burrin, D. G., 21 Jan 2013, In: Journal of Pediatric Gastroenterology and Nutrition. 56, 6, p. 623-30 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells

    Pedersen, J., Ugleholdt, Randi Kjærsgaard, Jørgensen, S. M., Windeløv, Johanne Agerlin, Grunddal, Kaare Villum, Schwartz, Thue W., Füchtbauer, E., Poulsen, Steen Seier, Holst, Peter Johannes & Holst, Jens Juul, 1 Jan 2013, In: American Journal of Physiology: Endocrinology and Metabolism. 304, 1, p. E60-73 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    A single supplement of a standardised bilberry (Vaccinium myrtillus L.) extract (36 % wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes controlled by diet and lifestyle

    Hoggard, N., Cruickshank, M., Moar, K., Bestwick, C., Holst, Jens Juul, Russell, W. & Horgan, G., 2013, In: Journal of Nutritional Science. 2, 9 p., e22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects

    Holmer-Jensen, J., Mortensen, L. S., Astrup, A., de Vrese, M., Holst, Jens Juul, Thomsen, C. & Hermansen, K., 2013, In: Nutrition Research. 33, 1, p. 34-40 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Combining GLP-1 receptor agonists with insulin: therapeutic rationales and clinical findings

    Holst, Jens Juul & Vilsbøll, Tina, 2013, In: Diabetes, Obesity and Metabolism. 15, 1, p. 3-14 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Contribution of gastroenteropancreatic appetite hormones to protein-induced satiety

    Sparre, A. B., Ritz, C., Sørensen, M. Q., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2013, In: American Journal of Clinical Nutrition. 97, 5, p. 980-989 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol

    Pedersen, L. R., Olsen, R. H., Frederiksen, M., Astrup, A., Chabanova, E., Hasbak, P., Holst, Jens Juul, Kjær, Andreas, Newman, J. W., Walzem, R., Wisløff, U., Sajadieh, Ahmad, Haugaard, Steen Bendix & Prescott, Eva, 2013, In: B M C Cardiovascular Disorders. 13, 1, 8 p., 106.

    Research output: Contribution to journalJournal articleResearchpeer-review

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