Carolyn F. Deacon

Carolyn F. Deacon

Associate Professor

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    ORCID: 0000-0003-2611-5642

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    1. Published

      A Protein Preload Enhances the Glucose-Lowering Efficacy of Vildagliptin in Type 2 Diabetes

      Wu, T., Little, T., Bound, M., Borg, M., Zhang, X., Deacon, Carolyn F., Horowitz, M., Jones, K. & Rayner, C., 2016, In: Diabetes Care. 39, 4, p. 511-517 7 p.

      Research output: Contribution to journal › Journal article › peer-review

    2. Published

      A carbohydrate-reduced high-protein diet acutely decreases postprandial and diurnal glucose excursions in type 2 diabetes patients

      Samkani, A., fbg982, fbg982, Kandel, D., Kjaer, S., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2018, In: British Journal of Nutrition. 119, 8, p. 910-917 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    3. Published

      A comparative review of DPP-4 inhibitors and sulphonylureas

      Deacon, Carolyn F. & Lebovitz, H., 2016, In: Diabetes, Obesity and Metabolism. 18, p. 333-347

      Research output: Contribution to journal › Journal article › peer-review

    4. Published

      A review of dipeptidyl peptidase-4 inhibitors: Hot topics from randomized controlled trials

      Deacon, Carolyn F., Feb 2018, In: Diabetes, Obesity and Metabolism. 20, p. 34-46 13 p.

      Research output: Contribution to journal › Review › peer-review

    5. Published

      A review of dipeptidyl peptidase-4 inhibitors. Hot topics from randomised controlled trials

      Deacon, Carolyn F., 2018, In: Diabetes, Obesity and Metabolism. 20, Suppl. 1, p. 34-46

      Research output: Contribution to journal › Review › peer-review

    6. Published

      A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite

      Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, J., Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291

      Research output: Contribution to journal › Journal article › peer-review

    7. Published

      Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow

      Jensen, E. P., Poulsen, Steen Seier, Kissow, Hannelouise, von Holstein-Rathlou, Niels-Henrik, Deacon, Carolyn F., Jensen, B. L., Holst, Jens Juul & Sorensen, Charlotte Mehlin, 15 Apr 2015, In: A J P: Renal Physiology (Online). 308, 8, p. F867-F877 11 p.

      Research output: Contribution to journal › Journal article › peer-review

    8. Published

      Acute administration of interleukin-6 does not increase secretion of glucagon-like peptide-1 in mice

      Christiansen, Charlotte Bayer, Jepsen, Sara Lind, Svendsen, B., Balk-Møller, E., Dahlby, T., Kuhre, Rune Ehrenreich, Hartmann, Bolette, Mandrup-Poulsen, Thomas, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2018, In: Physiological Reports. 6, 13, p. 1-8 e13788.

      Research output: Contribution to journal › Journal article › peer-review

    9. Published

      Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on incretin hormones

      Olthof, M., van Dijk, A., Deacon, Carolyn F., Heine, R. & van Dam, R., 2011, In: Nutrition & Metabolism. 8, p. Artikel 10 4 p.

      Research output: Contribution to journal › Journal article › peer-review

    10. Published

      Acute effects of dietary carbohydrate restriction on glycemia, lipemia and appetite regulating hormones in normal-weight to obese subjects

      Samkani, A. A., fbg982, fbg982, Thomsen, M. N., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Krarup, T. & Haugaard, Steen Bendix, 2018, In: Nutrients. 10, 9, 14 p., 1285.

      Research output: Contribution to journal › Journal article › peer-review

    11. Published

      Acute effects of linagliptin on intact and total glucagon-like peptide-1 and gastric inhibitory polypeptide levels in insulin-dependent type 2 diabetes patients with and without moderate renal impairment

      Meier, J. J., Quast, D. R., Nauck, M. A., Schenker, N., Deacon, Carolyn F., Holst, Jens Juul, Plum-Mörschel, L. & Kapitza, C., 2022, In: Diabetes, Obesity and Metabolism. 24, 5, p. 806-815

      Research output: Contribution to journal › Journal article › peer-review

    12. Published

      Acute effects on glucose tolerance by neprilysin inhibition in patients with type 2 diabetes

      Albrechtsen, Nicolai Jacob Wewer, Møller, A., Martinussen, C., Gluud, Lise Lotte, Rashu, E. B., Richter, Michael Martin, Plomgaard, Peter Stendahl, Goetze, Jens P. , Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2017-2026 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    13. Published

      Addition of a dipeptidyl peptidase-4 inhibitor, sitagliptin, to ongoing therapy with the glucagon-like peptide-1 receptor agonist liraglutide: A randomized controlled trial in patients with type 2 diabetes

      Nauck, M. A., Kahle, M., Baranov, O., Deacon, Carolyn F. & Holst, Jens Juul, 6 Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 200-207 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    14. Published

      Alogliptin, a potent and selective dipeptidyl peptidase-IV inhibitor for the treatment of type 2 diabetes.

      Deacon, Carolyn F., 2008, In: Current Opinion in Investigational Drugs. 9, 4, p. 402-13 11 p.

      Research output: Contribution to journal › Journal article › peer-review

    15. Published

      An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future

      Madsbad, Sten, Kielgast, U., Asmar, M., Deacon, Carolyn F., Torekov, Signe Sørensen & Holst, Jens Juul, May 2011, In: Diabetes, Obesity and Metabolism. 13, 5, p. 394-407 14 p.

      Research output: Contribution to journal › Journal article › peer-review

    16. Published

      Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent manner

      Jepsen, Sara Lind, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Farb, T. B., Kissow, Hannelouise, Pedersen, J., Deacon, Carolyn F., Martin, R. E. & Holst, Jens Juul, 2021, In: JCI insight. 6, 4, 15 p., e143228.

      Research output: Contribution to journal › Journal article › peer-review

    17. Published

      Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas.

      Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Larsen, Olav, Jepsen, Sara Lind, Balk-Møller, E., Andersen, Daniel Bjørklund, Deacon, Carolyn F., Schoonjans, K., Reimann, F., Gribble, F. M., Albrechtsen, Reidar, Hartmann, Bolette, Rosenkilde, Mette & Holst, Jens Juul, 2018, In: Molecular Metabolism. 11, p. 84-95 12 p.

      Research output: Contribution to journal › Journal article › peer-review

    18. Published

      Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.

      Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In: Diabetes. 44, p. 1126-1131

      Research output: Contribution to journal › Journal article › peer-review

    19. Published

      Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test

      Gjesing, A. P., Kjems, L. L., Vestmar, M. A., Grarup, Niels, Linneberg, Allan René, Deacon, Carolyn F., Holst, Jens Juul, Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: Diabetologia. 54, 1, p. 103-10 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    20. Published

      Cephalic phase secretion of insulin and other enteropancreatic hormones in humans

      Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 1 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 1, p. G43-51

      Research output: Contribution to journal › Journal article › peer-review

    21. Published

      Cerebral effects of glucagon-like peptide-1 receptor blockade before and after Roux-en-Y gastric bypass surgery in obese women: A proof-of-concept resting-state functional MRI study

      van Duinkerken, E., Bernardes, G., van Bloemendaal, L., Veltman, D. J., Barkhof, F., Mograbi, D. C., Gerdes, V. E. A., Deacon, Carolyn F., Holst, Jens Juul, Drent, M. L., Diamant, M., ten Kulve, J. & Ijzerman, R. G., 2021, In: Diabetes, Obesity and Metabolism. 23, 2, p. 415-424 10 p.

      Research output: Contribution to journal › Journal article › peer-review

    22. Published

      Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty

      Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendal, C., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 23 May 2013, In: European Journal of Endocrinology. 169, p. 187-201 14 p.

      Research output: Contribution to journal › Journal article › peer-review

    23. Published

      Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

      Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Hornburg, D., Jensen, C. Z., Hornum, Mads, Dirksen, C., Svane, M., Gasbjerg, Lærke Smidt, Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, Reidar, Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Meissner, F., Jorsal, T., Lund, A., Vilsbøll, Tina, Eliasen, R., Bojsen-Moller, K. N., Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

      Research output: Contribution to journal › Journal article › peer-review

    24. Published

      Circulation and degradation of GIP and GLP-1

      Deacon, Carolyn F., 2004, In: Hormone and Metabolic Research. 36, p. 761-765

      Research output: Contribution to journal › Journal article › peer-review

    25. Published

      Commentary: Is endogenous GLP-1 the only important enhancer of glucose-induced insulin secretion in type 2 diabetes?

      Deacon, Carolyn F., 2012, In: Diabetes. 61, 9, p. 2219-2220

      Research output: Contribution to journal › Journal article › peer-review

    26. Published

      Comparative review of dipeptidyl peptidase-4 inhibitors and sulphonylureas.

      Deacon, Carolyn F. & Lebovitz, H., 2016, In: Diabetes, Obesity and Metabolism. 18, 4, p. 333-347 15 p.

      Research output: Contribution to journal › Review › peer-review

    27. Published

      Critical role for GLP-1 in symptomatic post-bariatric hypoglycaemia

      Craig, C. M., Liu, L., Deacon, Carolyn F., Holst, Jens Juul & McLaughlin, T. L., Mar 2017, In: Diabetologia. 60, 3, p. 531-540

      Research output: Contribution to journal › Journal article › peer-review

    28. Published

      DPP-4 inhibition – advances in our understanding of diabetes management

      Deacon, Carolyn F. & Holst, Jens Juul, 2009, In: European Endocrinology. 4, p. 47-49

      Research output: Contribution to journal › Review

    29. Published

      DPP-4 inhibitor therapy: new directions in the treatment of type 2 diabetes

      Deacon, Carolyn F., Carr, R. D. & Holst, Jens Juul, 2008, In: Frontiers in Bioscience. 13, p. 1780-94 14 p.

      Research output: Contribution to journal › Journal article › peer-review

    30. Published

      DPP-4 inhibitors

      Deacon, Carolyn F., 2016, Handbook of incretin therapies in type 2 diabetes. Gough, S. (ed.). Switzerland: Springer, p. 45-60

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

    31. Published

      Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide

      Deacon, Carolyn F., Nauck, M. A., Meier, J., Hücking, K. & Holst, Jens Juul, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, p. 3575-3581

      Research output: Contribution to journal › Journal article › peer-review

    32. Published

      Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo.

      Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, p. 952-957

      Research output: Contribution to journal › Journal article › peer-review

    33. Published

      Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men

      Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., 2017, In: European Journal of Nutrition. 56, 3, p. 1063-1076 14 p.

      Research output: Contribution to journal › Journal article › peer-review

    34. Published

      Differential islet and incretin hormone responses in morning versus afternoon after standardized meal in healthy men

      Lindgren, O., Mari, A., Deacon, Carolyn F., Carr, R. D., Winzell, M. S., Vikman, J. & Ahrén, B., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 8, p. 2887-92 5 p.

      Research output: Contribution to journal › Journal article › peer-review

    35. Published

      Differential regional metabolism of glucagon in anesthetized pigs.

      Deacon, Carolyn F., Kelstrup, M., Trebbien, R., Klarskov, L., Olesen, M. & Holst, Jens Juul, 2003, In: American Journal of Physiology: Endocrinology and Metabolism. 285, 3, p. E552-60

      Research output: Contribution to journal › Journal article › peer-review

    36. Published

      Dipeptidyl peptidase 4 inhibition with sitagliptin: a new therapy for type 2 diabetes.

      Deacon, Carolyn F., 2007, In: Expert Opinion on Investigational Drugs. 16, 4, p. 533-45 12 p.

      Research output: Contribution to journal › Journal article › peer-review

    37. Published

      Dipeptidyl peptidase 4 inhibitors in the treatment of type 2 diabetes mellitus

      Deacon, Carolyn F., 2020, In: Nature Reviews Endocrinology. 16, 11, p. 642-653

      Research output: Contribution to journal › Review › peer-review

    38. Published

      Dipeptidyl peptidase IV inhibition as an approach to the treatment and prevention of type 2 diabetes: a historical perspective.

      Deacon, Carolyn F. & Holst, Jens Juul, 2002, In: Biochemical and Biophysical Research Communications. 294, 1, p. 1-4 3 p.

      Research output: Contribution to journal › Journal article › peer-review

    39. Published

      Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.

      Deacon, Carolyn F., Hughes, T. E. & Holst, Jens Juul, 1998, In: Diabetes. 47, p. 764-769

      Research output: Contribution to journal › Journal article › peer-review

    40. Published

      Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs

      Deacon, Carolyn F., Danielsen, P., Klarskov, L., Holst, Jens Juul & Olesen, M., 2001, In: Diabetes. 50, p. 1588-1597

      Research output: Contribution to journal › Journal article › peer-review

    41. Published

      Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes.

      Deacon, Carolyn F. & Holst, Jens Juul, 2005, In: International Journal of Biochemistry & Cell Biology. 38, 5-6, p. 831-44 13 p.

      Research output: Contribution to journal › Journal article › peer-review

    42. Published

      Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

      Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In: Diabetologia. 41, p. 271-278

      Research output: Contribution to journal › Journal article › peer-review

    43. Published

      Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs

      Hjøllund, K. R., Deacon, Carolyn F. & Holst, Jens Juul, 2011, In: Diabetologia. 54, 8, p. 2206-8 3 p.

      Research output: Contribution to journal › Letter › peer-review

    44. Published

      Dipeptidyl peptidase-4 inhibitors administered in combination with metformin result in an additive increase in the plasma concentration of active GLP-1

      Migoya, E. M., Bergeron, R., Miller, J. L., Snyder, R. N. K., Tanen, M., Hilliard, D., Weiss, B., Larson, P., Gutierrez, M., Jiang, G., Liu, F., Pryor, K. A., Yao, J., Zhu, L., Holst, Jens Juul, Deacon, Carolyn F., Herman, G., Thornberry, N., Amatruda, J., Williams-Herman, D., Wagner, J. A. & SinhaRoy, R., 1 Dec 2010, In: Clinical Pharmacology and Therapeutics. 88, 6, p. 801-8 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    45. Published

      Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety

      Deacon, Carolyn F. & Holst, Jens Juul, Oct 2013, In: Expert Opinion on Pharmacotherapy. 14, 15, p. 2047-58 12 p.

      Research output: Contribution to journal › Journal article › peer-review

    46. Published

      Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: A comparative review

      Deacon, Carolyn F., Jan 2011, In: Diabetes, Obesity and Metabolism. 13, 1, p. 7-18 12 p.

      Research output: Contribution to journal › Review › peer-review

    47. Published

      Dissociated incretin hormone response to protein versus fat ingestion in obese subjects

      Lindgren, O., Carr, R., Holst, Jens Juul, Deacon, Carolyn F. & Ahren, B., Jul 2011, In: Diabetes, Obesity and Metabolism Online. 13, 9, p. 863-865 3 p.

      Research output: Contribution to journal › Journal article › peer-review

    48. Published

      Do sodium-glucose transporter-2 inhibitors increase plasma glucagon by direct actions on the alpha-cell? - and does the increase matter for the associated increase in endogenous glucose production?

      Kuhre, Rune Ehrenreich, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2021, In: Diabetes, Obesity and Metabolism. 23, 9, p. 2009-2019

      Research output: Contribution to journal › Review › peer-review

    49. Published

      Do we know the true mechanism of action of the DPP-4 inhibitors?

      Andersen, E. S., Deacon, Carolyn F. & Holst, Jens Juul, 2018, In: Diabetes, Obesity and Metabolism. 20, 1, p. 34-41 8 p.

      Research output: Contribution to journal › Journal article › peer-review

    50. Published

      Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.

      Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Windeløv, Johanne Agerlin, Ørgaard, A., Deacon, Carolyn F., Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E302-E309 8 p.

      Research output: Contribution to journal › Journal article › peer-review

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