Helge Group – Integrative Exercise Physiology

Whole body

• Body composition Dual-Energy X-ray Absorptiometry (DEXA scan)
• Fat oxidation at rest and during exercise (Maximal fat oxidation)
• Maximal oxygen uptake VO_2max (bike, treadmill, skiing ergometer)
• Assessment of VO_2max using a medical device Seismofit (Ventriject A/S)
• Assessment of endurance capacity (yo-Yo tests, treadmill, etc.)

Tissue analysis

• Muscle biopsies (substrates, enzymes, lipidomics)
• Mitochondrial function (collaboration with Assoc. prof. Steen Larsen)
• Adipose tissue biopsies (inflammation & macrophages)
• Blood analysis (FFA, Ketones, Catecholamines, etc.)

In analysis

• Effects of 84 hours fasting on MFO and Mitochondrial coupling in young and old men
• Effects of training on 1) adipose tissue and low-grade inflammation 2) plasma and muscle tissue lipidomics in matched obese and T2D individuals.
• Effects of glycogen content on MFO and Mitochondrial coupling in young men.
• Effects of training, muscle-type, and ethnicity on skeletal muscle lipidomics.

In process

• The variation in physiological training parameters across an annual cycle in elite athletes (soccer, swimming)
• Evaluation of Seismofit- estimation of VO_2max in patients with knee arthritis before and after training
• Influence of BMI and age on adipose tissue extracellular matrix
• Variation of maximal fat oxidation in upper/lower/and combined exercise in normal trained or upper body trained athletes.

• Assoc. Prof. Steen Larsen, Department of Biomedical Science, University of Copenhagen (UCPH), Denmark.
• Nils Færgeman, University of Southern Denmark, Odense, Denmark
• Prof. Chris Shaw, University of Deakin, Geelong, Victoria, Australia
• Assoc, Prof. Christoffer Clemmensen, Center of Basic Metabolism, UCPH.
• Assoc. Prof. Katrine Schjoldager, Department of Cellular and Molecular Medicine, UCPH.
• Professor Peter Meikle, Baker Heart and Diabetes Institute, Melbourne, Australia
• Prof. Mette Hansen, Centre of Sports Science, Aarhus University, Aarhus, Denmark
• Jose Calbet, University of Las Palmas, Las Palmas, Spain
• Paul Greenhaff, University of Nottingham, Nottingham, UK
• Consultant in Cardiology, Morten Kjøbek Lamberts, Gentofte-Herlev Hospital, Denmark
• Consultant in Cardiology, Emil Wolsk, Gentofte-Herlev Hospital, Denmark
• Prof. Christina Blasco-Lafarga, University of Valencia, Valencia, Spain

I collaborate with the Danish Biotech company Ventriject A/S (https://ventriject.com/), and on a project Grant with Novo Nordisk A/S. In addition, I have had a long-standing collaboration (> 10 yrs.) with the now closed Ubberup Højskole.

• Novo Nordisk A/S
• Ventriject A/S
• Per Henriksens Fond
• Carlsberg Fonden