Thomas Jespersen

Thomas Jespersen

Professor

Member of:

    ORCID: 0000-0001-6575-360X

    Publication year:
    All
    1 - 100 out of 185Page size: 100
    1. 1997
    2. Published

      Efficient non-PCR-mediated overlap extension of PCR fragments by exonuclease "end polishing"

      Jespersen, Thomas, Duch, M. R. & Pedersen, F. S., 1 Jul 1997, In: BioTechniques. 23, 1, p. 48, 50, 52

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. 1999
    4. Published

      Analysis and exploitation of murine leukemia virus cis- and trans-elements using novel transduction systems

      Jespersen, Thomas, 3 Mar 1999

      Research output: Book/Report › Ph.D. thesis › Research

    5. Published

      Functional testing of a bicistronic retroviral vector for intracellular peptide production

      Duch, M. R., Tolstrup, A., Dalum, I., Jespersen, Thomas, Mouritsen, S. & Pedersen, F. S., 1 Jun 1999, In: BioTechniques. 26, 6, p. 1032-4, 1036

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Expression of heterologous genes from an IRES translational cassette in replication competent murine leukemia virus vectors

      Jespersen, Thomas, Duch, M. R., Carrasco, M. L., Warming, S. & Pedersen, F. S., 1 Nov 1999, In: Gene. 239, 2, p. 227-35 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. 2001
    8. Published

      An ERG channel inhibitor from the scorpion Buthus eupeus

      Korolkova, Y. V., Kozlov, S. A., Lipkin, A. V., Pluzhnikov, K. A., Hadley, J. K., Filippov, A. K., Brown, D. A., Pedersen, K. A., Strøbaek, D., Jespersen, Thomas, Olesen, Søren-Peter, Jensen Skanning, B. & Grishin, E. V., 30 Mar 2001, In: Journal of Biological Chemistry. 276, 13, p. 9868-76 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      KCNQ4 channel activation by BMS-204352 and retigabine

      Schrøder, R. L. K., Jespersen, Thomas, Christophersen, P., Strøbaek, D., Jensen, B. S. & Olesen, Poul, 1 Jun 2001, In: Neuropharmacology. 40, 7, p. 888-98 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Pharmacological modulation of SK3 channels

      Grunnet, Morten, Jespersen, Thomas, Angelo, K., Frøkjær-Jensen, Christian, Klærke, Dan Arne, Olesen, Poul & Jensen, B. S., 1 Jun 2001, In: Neuropharmacology. 40, 7, p. 879-887 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. 2002
    12. Published

      Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352.

      Dupuis, D. S., Schrøder, R. L., Jespersen, Thomas, Christensen, J. K., Christophersen, P., Jensen, B. S. & Olesen, Søren-Peter, 2002, In: European Journal of Pharmacology. 437, 3, p. 129-37 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      KCNE4 is an inhibitory subunit to the KCNQ1 channel.

      Grunnet, Morten, Jespersen, Thomas, Rasmussen, Hanne Borger, Ljungstrøm, T., Jorgensen, N. K., Olesen, Søren-Peter & Klærke, Dan Arne, 2002, In: Journal of Physiology. 542, Pt 1, p. 119-30 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.

      Angelo, K., Jespersen, Thomas, Grunnet, Morten, Nielsen, Morten Schak, Klærke, Dan Arne & Olesen, Søren-Peter, 2002, In: Biophysical Journal. 83, 4, p. 1997-2006 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes

      Jespersen, Thomas, Grunnet, Morten, Angelo, K., Klærke, Dan Arne & Olesen, Poul, 1 Mar 2002, In: BioTechniques. 32, 3, p. 536-8, 540

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. 2003
    17. Published

      Characterization of two new dominant ClC-1 channel mutations associated with myotonia.

      Grunnet, Morten, Jespersen, Thomas, Colding-Jørgensen, E., Schwartz, M., Klærke, Dan Arne, Vissing, John, Olesen, Søren-Peter & Dunø, M., 2003, In: Muscle & Nerve. 28, 6, p. 722-32 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.

      Grunnet, Morten, Rasmussen, H. B., Hay-Schmidt, Anders, Rosenstierne, M., Klærke, Dan Arne, Olesen, Søren-Peter & Jespersen, Thomas, 2003, In: Biophysical Journal. 85, 3, p. 1525-37 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      KCNQ1 channels sense small changes in cell volume.

      Grunnet, Morten, Jespersen, Thomas, MacAulay, Nanna, Jørgensen, N. K., Schmitt, Nicole, Pongs, O., Olesen, Søren-Peter & Klærke, Dan Arne, 2003, In: Journal of Physiology. 549, Pt 2, p. 419-27 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Solid-phase synthesis and biological activity of a thioether analogue of conotoxin G1.

      Bondebjerg, J., Grunnet, Morten, Jespersen, Thomas & Meldal, Morten Peter, 2003, In: ChemBioChem. 4, 2-3, p. 186-94 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Mutational library analysis of selected amino acids in the receptor binding domain of envelope of Akv murine leukemia virus by conditionally replication competent bicistronic vectors

      Bahrami, S., Jespersen, T., Pedersen, F. S., Duch, M. R. & Jespersen, Thomas, 2 Oct 2003, In: Gene. 315, p. 51-61 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. 2004
    23. Published

      5-HT1A receptors modulate small-conductance Ca2+-activated K+ channels.

      Grunnet, Morten, Jespersen, Thomas & Perrier, J., 2004, In: Journal of Neuroscience Research. 78, 6, p. 845-54 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif.

      Jespersen, Thomas, Rasmussen, Hanne Borger, Grunnet, Morten, Jensen, H. S., Angelo, K., Dupuis, D. S., Vogel, L. K., Jorgensen, N. K., Klærke, Dan Arne & Olesen, Søren-Peter, 2004, In: Journal of Cell Science. 117, Pt 19, p. 4517-26 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Difference in allelic expression of the CLCN1 gene and the possible influence on the myotonia congenita phenotype.

      Dunø, M., Colding-Jørgensen, E., Grunnet, Morten, Jespersen, Thomas, Vissing, John & Schwartz, M., 2004, In: European Journal of Human Genetics. 12, 9, p. 738-43 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Does KCNE5 play a role in long QT syndrome?

      Hofman-Bang, J., Jespersen, Thomas, Grunnet, Morten, Larsen, Lars Allan, Andersen, P. S., Kanters, Jørgen K., Kjeldsen, K. & Christiansen, M., 2004, In: Clinica Chimica Acta. 345, 1-2, p. 49-53 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins.

      Rougier, J., van Bemmelen, M. X., Bruce, M. C., Jespersen, Thomas, Gavillet, B., Apothéloz, F., Cordonier, S., Staub, O., Rotin, D. & Abriel, H., 2004, In: American Journal of Physiology: Cell Physiology. 288, 3, p. C692-701

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Recruitment of motor neuronal persistent inward currents shapes withdrawal reflexes in the frog

      Grunnet, Morten, Jespersen, Thomas & Perrier, Jean-Francois Marie, 2004, In: Journal of Neuroscience Research. 78, p. 845-854

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo

      Duch, M. R., Carrasco, M. L., Jespersen, T., Aagaard, L., Pedersen, F. S. & Jespersen, Thomas, 1 Jan 2004, In: Nucleic Acids Symposium Series. 32, 6, p. 2039-48 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Transgene stability for three replication-competent murine leukemia virus vectors

      Duch, M. R., Carrasco, M. L., Jespersen, T., Hansen, B. D., Pedersen, F. S. & Jespersen, Thomas, 31 Mar 2004, In: Gene. 329, p. 61-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. 2005
    32. Published

      The KCNQ1 potassium channel: from gene to physiological function.

      Jespersen, Thomas, Grunnet, Morten & Olesen, Søren-Peter, 2005, In: Physiology. 20, p. 408-16 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes.

      Jensen, H. S., Callø, Kirstine, Jespersen, Thomas, Jensen, B. S. & Olesen, Søren-Peter, 2005, In: Brain Research. 139, 1, p. 52-62 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      hKCNE4 inhibits the hKCNQ1 potassium current without affecting the activation kinetics.

      Grunnet, Morten, Olesen, Søren-Peter, Klærke, Dan Arne & Jespersen, Thomas, 2005, In: Biochemical and Biophysical Research Communications. 328, 4, p. 1146-53 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. 2006
    36. Published

      Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1.

      Jespersen, Thomas, Gavillet, B., van Bemmelen, M. X., Cordonier, S., Thomas, M. A., Staub, O. & Abriel, H., 2006, In: Biochemical and Biophysical Research Communications. 348, 4, p. 1455-62 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Kondo physics in tunable semicondouctor nanowire quantum dots

      Jespersen, Thomas, Aagesen, M., Sørensen, Claus Birger, Lindelof, Poul Erik & Nygård, Jesper, 2006, In: Physical Review B. Condensed Matter and Materials Physics. 74, 23, p. 233304

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Subtype-specific, bi-component inhibition of SK channels by low internal pH.

      Peitersen, T., Jespersen, Thomas, Jorgensen, N. K., Olesen, Søren-Peter & Grunnet, Morten, 2006, In: Biochemical and Biophysical Research Communications. 343, 3, p. 943-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      The corticosteroid hormone induced factor: a new modulator of KCNQ1 channels?

      Jespersen, Thomas, Grunnet, Morten, Rasmussen, Hanne Borger, Jørgensen, N. B., Jensen, H., Angelo, K., Olesen, Søren-Peter & Klærke, Dan Arne, 2006, In: Biochemical and Biophysical Research Communications. 341, 4, p. 979-88 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. 2007
    41. Published

      Brugada syndrome unmasked by accidental inhalation of gasoline vapors.

      Kranjcec, D., Bergovec, M., Rougier, J., Raguz, M., Pavlovic, S., Jespersen, Thomas, Castella, V., Keller, D. I. & Abriel, H., 2007, In: Pacing and Clinical Electrophysiology. 30, 10, p. 1294-8 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family.

      Jespersen, Thomas, Membrez, M., Nicolas, C. S., Pitard, B., Staub, O., Olesen, Søren-Peter, Baró, I. & Abriel, H., 2007, In: Cardiovascular Research. 74, 1, p. 64-74 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. 2008
    44. Published

      Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome.

      Petitprez, S., Jespersen, Thomas, Pruvot, E., Keller, D. I., Corbaz, C., Schläpfer, J., Abriel, H. & Kucera, J. P., 2008, In: Cardiovascular Research. 78, 3, p. 494-504 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Antiarrhythmic effect of IKr activation in a cellular model of LQT3

      Diness, Jonas Goldin, Hansen, R. S., Nissen, J. D., Jespersen, Thomas & Grunnet, Morten, 2008, In: Heart Rhythm. 6, 1, p. 100-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.

      Larsen, A. P., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, 2008, In: Pflügers Archiv: European Journal of Physiology. 456, 6, p. 1137-48 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. 2009
    48. Published

      A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease

      Holst, A. G., Callø, Kirstine, Jespersen, Thomas, Cedergreen, P., Winkel, B. G., Jensen, H. K., Leren, T. P., Haunso, S., Svendsen, Jesper Hastrup & Tfelt-Hansen, J., 2009, In: Case Reports in Medicine. 2009, p. 963645

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury

      Bentzen, Bo Hjorth, Osadchii, O., Jespersen, Thomas, Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2009, In: Pflügers Archiv: European Journal of Physiology. 457, 5, p. 979-88 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Arvelige hjertesygdomme forårsaget af natriumkanalmutationer

      Tfelt-Hansen, J., Olesen, Søren-Peter, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2009, In: Ugeskrift for læger. 171, 15, p. 1261-5 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

      Callø, Kirstine, Soltysinska, E., Jespersen, Thomas, Lundby, Alicia, Antzelevitch, C., Olesen, Søren-Peter & Cordeiro, J. M., 2009, In: Journal of Molecular and Cellular Cardiology. 48, 1, p. 191-200 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Inherited Cardiac Diseases Caused by Mutations in the Nav1.5 Sodium Channel

      Tfelt-Hansen, J., Winkel, B. G., Grunnet, Morten & Jespersen, Thomas, 2009, In: Cardiovascular Electrophysiology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Pharmacologically induced long QT type 2 can be rescued by activation of IKs with benzodiazepine R-L3 in isolated guinea pig cardiomyocytes

      Nissen, J. D., Diness, Jonas Goldin, Diness, T. G., Hansen, R. S., Grunnet, Morten & Jespersen, Thomas, 2009, In: Journal of Cardiovascular Pharmacology. 54, 2, p. 169-77 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts

      Soltysinska, E., Olesen, Søren-Peter, Christ, T., Wettwer, E., Varró, A., Grunnet, Morten & Jespersen, Thomas, 2009, In: Pflügers Archiv: European Journal of Physiology. 459, 1, p. 11-23 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A

      Tfelt-Hansen, J., Jespersen, Thomas, Hofman-Bang, J., Rasmussen, Hanne Borger, Cedergreen, P., Skovby, F., Abriel, H., Svendsen, Jesper Hastrup, Olesen, S., Christiansen, M. & Haunso, S., 2009, In: Canadian Journal of Cardiology. 25, 3, p. 156-60 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      Inherited cardiac diseases caused by mutations in the Nav1.5 sodium channel.

      Tfelt-Hansen, Jacob, Winkel, B., Grunnet, Morten & Jespersen, Thomas, Oct 2009, In: Journal of Cardiovascular Electrophysiology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. 2010
    58. Published

      Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome

      Yang, Y., Yang, Y., Liang, B., Liu, J., Li, J., Grunnet, M., Olesen, S-P., Rasmussen, H. B., Ellinor, P. T., Gao, L., Lin, X., Li, L., Wang, L., Xiao, J., Liu, Y., Liu, Y., Zhang, S., Liang, D., Peng, L., Jespersen, T. & 1 others, Chen, Y., 2010, In: American Journal of Human Genetics. 86, 6, p. 872-80 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Sick sinus syndrome, progressive cardiac conduction disease, atrial flutter and ventricular tachycardia caused by a novel SCN5A mutation

      Holst, A. G., Liang, B., Jespersen, Thomas, Bundgård, Henning, Haunso, S., Svendsen, Jesper Hastrup & Tfelt-Hansen, J., 2010, In: Cardiology. 115, 4, p. 311-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Inhibition of small-conductance Ca2+-activated K+ channels terminates and protects against atrial fibrillation

      Diness, Jonas Goldin, Sørensen, U. S., Nissen, J. D., Al-Shahib, B., Jespersen, T., Grunnet, Morten, Hansen, R. S. & Jespersen, Thomas, Aug 2010, In: Circulation. Arrhythmia and electrophysiology. 3, 4, p. 380-90 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. 2011
    62. Published

      Atrieflimmer og elektrofysiologi hos heste

      Haugaard, M. M., Buhl, Rikke & Jespersen, Thomas, 2011, In: Dansk Veterinaertidsskrift. 12, p. 28-31 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      Cardiac channelopathies and sudden infant death syndrome

      Tfelt-Hansen, J., Winkel, B. G., Grunnet, Morten & Jespersen, Thomas, 2011, In: The Cardiology. 119, 1, p. 21-33 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. Published

      Characterization of cardiac repolarization in the Göttingen minipig

      Laursen, M., Olesen, Søren-Peter, Grunnet, Morten, Mow, T., Jespersen, T. & Jespersen, Thomas, 2011, In: Journal of Pharmacological and Toxicological Methods. 63, 2, p. 186-95 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. Published

      Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded from Atrial and Ventricular Cardiomyocytes.

      Callø, Kirstine, Nof, E., Jespersen, Thomas, Di Diego, J. M., Chlus, N., Olesen, Søren-Peter, Antzelevitch, C. & Cordeiro, J. M., 2011, In: Journal of Cardiovascular Electrophysiology. 22, 9, p. 1057-1066 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. Published

      Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition

      Diness, Jonas Goldin, Skibsbye, L., Jespersen, Thomas, Bartels, Emil Daniel, Sørensen, U. S., Hansen, R. S. & Grunnet, Morten, 2011, In: Hypertension. 57, 6, p. 1129-35 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    67. Published

      Mutations in sodium channel {beta}-subunit SCN3B are associated with early-onset lone atrial fibrillation

      Olesen, M. S., Jespersen, Thomas, Nielsen, J. B., Liang, B., Møller, D. V., Hedley, P., Christiansen, M., Varro, A., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole & Svendsen, Jesper Hastrup, 2011, In: Cardiovascular Research. 89, 4, p. 786-793 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. Published

      Regulation and physiological function of Na(v) 1.5 and KCNQ1 channels

      Jespersen, Thomas, 2011, In: Acta Physiologica (Print). 202 Suppl 683, p. 1-26 26 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. Published

      Screening of KCNN3 in patients with early-onset lone atrial fibrillation

      Olesen, M. S., Jabbari, J., Holst, A. G., Nielsen, J. B., Steinbrüchel, D. A., Jespersen, T., Haunsø, Stig, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2011, In: Europace. 13, 7, p. 963-967 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      A Novel Nonsense Variant in Nav1.5 Cofactor MOG1 Eliminates Its Sodium Current Increasing Effect and May Increase the Risk of Arrhythmias

      Olesen, M. S., Jensen, N. F., Holst, A. G., Nielsen, J. B., Tfelt-Hansen, Jacob, Jespersen, Thomas, Sajadieh, Ahmad, Haunsø, Stig, Lund, J. T., Callø, Kirstine, Schmitt, Nicole & Svendsen, Jesper Hastrup, 26 May 2011, In: Canadian Journal of Cardiology. 27, 4, p. 523.e17-23

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. 2012
    72. Published

      AMP-activated protein kinase downregulates Kv7.1 cell surface expression

      Andersen, M. N., Krzystanek, K., Jespersen, Thomas, Olesen, Søren-Peter & Rasmussen, Hanne Borger, 2012, In: Traffic. 13, 1, p. 143-56 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    73. Published

      Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure

      Nissen, J. D., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Diness, Jonas Goldin, Diness, T. G., Jespersen, Thomas & Grunnet, Morten, 2012, In: Journal of Cardiovascular Pharmacology. 59, 2, p. 142-150 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    74. Published

      Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels

      Krzystanek, K., Rasmussen, Hanne Borger, Grunnet, Morten, Staub, O., Olesen, Søren-Peter, Abriel, H. & Jespersen, Thomas, 2012, In: Heart Rhythm. 9, 3, p. 440-8 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    75. Published

      High Prevalence of Long QT Syndrome Associated SCN5A Variants in Patients with Early-Onset Lone Atrial Fibrillation

      Olesen, M. S., Yuan, L., Liang, B., Holst, A. G., Nielsen, N., Nielsen, J. B., Hedley, P. L., Christiansen, M., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole, Jespersen, Thomas & Svendsen, Jesper Hastrup, 2012, In: Circulation: Cardiovascular Genetics. 5, 4, p. 450-459 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    76. Published

      Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts

      Laursen, M., Grunnet, Morten, Olesen, Søren-Peter, Jespersen, Thomas & Mow, T., 2012, In: Journal of Pharmacological and Toxicological Methods. 64, 2, p. 134-44 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Published

      Cardiac Arrhythmia - new considerations: The Cardiac Ion Channels

      Jespersen, Thomas, 29 Feb 2012, Cardiac Arrhythmias - new considerations. Breijo-Marquez, F. R. (ed.). Croatia: InTech, p. 45-72 29 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    78. Published

      Functionally Selective AT(1) Receptor Activation Reduces Ischemia Reperfusion Injury

      Hostrup, A., Christensen, G. L., Bentzen, Bo Hjorth, Liang, B., Aplin, M., Grunnet, Morten, Hansen, J. L. & Jespersen, Thomas, 30 Jul 2012, In: Cellular Physiology and Biochemistry. 30, 3, p. 642-652 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. 2013
    80. Published

      Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization

      Jørgensen, S. T., Eriksen, H. N., Dausell, J., Jespersen, Thomas, Lambert, Ian Henry & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 31, 2-3, p. 366-378 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. Published

      GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology

      Wang, X., Liang, B., Skibsbye, L., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, Aug 2013, In: Journal of Cardiovascular Pharmacology. 62, 2, p. 192-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    82. Published

      The role of CAV3 in long-QT syndrome: clinical and functional assessment of a caveolin-3/Kv11.1 double heterozygote versus caveolin-3 single heterozygote

      Hedley, P. L., Kanters, Jørgen K., Dembic, M., Jespersen, Thomas, Skibsbye, L., Aidt, F. H., Eschen, O., Graff, C., Behr, E. R., Schlamowitz, S., Corfield, V., McKenna, W. J. & Christiansen, M., Oct 2013, In: Circulation: Cardiovascular Genetics. 6, 5, p. 452-61 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. Published

      A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

      Andersen, M. N., Krzystanek, K., Petersen, F., Bomholtz, Sofia Hammami, Olesen, Søren-Peter, Abriel, H., Jespersen, Thomas & Rasmussen, Hanne Borger, 8 Nov 2013, In: The Journal of Biological Chemistry. 288, 52, p. 36841-54 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    84. 2014
    85. Published

      G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

      Liang, B., Nissen, J. D., Laursen, M., Wang, X., Skibsbye, L., Hearing, M. C., Andersen, M. N., Rasmussen, Hanne Borger, Wickman, K., Grunnet, Morten, Olesen, Søren-Peter & Jespersen, Thomas, 1 Jan 2014, In: Cardiovascular Research. 101, 1, p. 175-84 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    86. Published

      Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.

      Yuan, L., Koivumäki, J., Liang, B., Lorentzen, Lasse Gøbel, Tang, C., Andersen, M., Svendsen, J., Tfelt-Hansen, Jacob, Maleckar, M., Schmitt, Nicole, Olesen, M. & Jespersen, Thomas, Feb 2014, In: American journal of physiology. Heart and circulatory physiology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    87. Published

      Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada Syndrome mutant

      Yuan, L., Koivumaki, J., Liang, B., Lorentzen, L. G., Tang, C., Andersen, M. N., Svendsen, Jesper Hastrup, Tfelt-Hansen, J., Maleckar, M., Schmitt, Nicole, Olesen, Morten Steen Salling & Jespersen, Thomas, 21 Feb 2014, In: American Journal of Physiology: Heart and Circulatory Physiology. 306, 8, p. H1204-12

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. Published

      Flecainide provocation reveals concealed brugada syndrome in a long QT syndrome family with a novel L1786Q mutation in SCN5A. SCN5A mutations associated with overlap phenotype of long QT syndrome type 3 and Brugada syndrome.

      Kanters, Jørgen K., Yuan, L., Hedley, P. L., Stoevring, B., Jons, C., Bloch Thomsen, P. E., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 6 Mar 2014, In: Circulation Journal. 78, 5, p. 1136-43 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. Published

      Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarisation in human atria.

      Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-167 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    90. Published

      Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria

      Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, 1 Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-67 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    91. 2015
    92. Published

      Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses

      Haugaard, M. M., Pehrson, S., Carstensen, Helena, Madsen, M. F., Hesselkilde, E. Z., Præstegaard, K. F., Diness, J. G., Grunnet, M., Jespersen, Thomas & Buhl, Rikke, 2015, In: Journal of Veterinary Internal Medicine. 29, 1, p. 339-347 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    93. Published

      Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family

      Kanters, Jørgen K., Skibsbye, L., Hedley, P. L., Dembic, M., Liang, B., Hagen, C. M., Eschen, O., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 2015, In: Scandinavian Journal of Clinical & Laboratory Investigation. 75, 8, p. 699-709 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Published

      Common and rare variants in SCN10A modulate the risk of atrial fibrillation.

      Jabbari, J., Olesen, Morten Steen Salling, Yuan, L., Nielsen, J. B., Liang, B., Macri, V., Christophersen, I. E., Nielsen, N., Sajadieh, Ahmad, Ellinor, P. T., Grunnet, Morten, Haunsø, Stig, Holst, A. G., Svendsen, Jesper Hastrup & Jespersen, Thomas, 2015, In: Circulation: Cardiovascular Genetics. 8, 1, p. 64-73 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. Published

      PKC and AMPK regulation of Kv1.5 potassium channels

      Andersen, M. N., Skibsbye, L., Tang, C., Petersen, F., MacAulay, Nanna, Rasmussen, Hanne Borger & Jespersen, Thomas, 2015, In: Channels (Austin). 9, 3, p. 121-8 8 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    96. Published

      Synergistic antiarrhythmic effect of combining inhibition of Ca(2+)-activated K(+) (SK) channels and voltage-gated Na(+) channels in an isolated heart model of atrial fibrillation

      Kirchhoff, J. E., Goldin Diness, J., Sheykhzade, Majid, Grunnet, M. & Jespersen, Thomas, Feb 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 2, p. 409-18 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    97. Published

      Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses

      Haugaard, M. M., Hesselkilde, E. Z., Pehrson, S. M., Carstensen, Helena, Madsen, M. F., Præstegaard, K. F., Sørensen, U. S., Diness, J. G., Grunnet, M., Buhl, Rikke & Jespersen, Thomas, Apr 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 4, p. 825-835 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    98. Published

      Antiarrhythmic effect of either negative modulation or blockade of small conductance Ca2+ activated K+ channels on ventricular fibrillation in guinea pig Langendorff perfused heart

      Diness, J. G., Kirchhoff, J. E., Sheykhzade, Majid, Jespersen, Thomas & Grunnet, M., 8 May 2015, In: Journal of Cardiovascular Pharmacology. 66, 3, p. 294–299 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Published

      The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome

      Winkel, B. G., Yuan, L., Olesen, Morten Steen Salling, Sadjadieh, G., Wang, Y., Risgaard, B., Jabbari, R., Haunsø, Stig, Holst, A. G., Hollegaard, M. V., Tfelt-Hansen, J. & Jespersen, Thomas, Jun 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 6, p. 1241-1249 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Published

      Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation

      Poulet, C., Wettwer, E., Grunnet, Morten, Jespersen, Thomas, Fabritz, L., Matschke, K., Knaut, M. & Ravens, U., 29 Jun 2015, In: PLOS ONE. 10, 6, p. 1-19 19 p., e0131432.

      Research output: Contribution to journal › Journal article › Research › peer-review

    101. Published

      Biophysical characterization of KV3.1 potassium channel activating compounds

      Taskin, B., von Schoubye, N. L., Sheykhzade, Majid, Bastlund, J. F., Grunnet, M. & Jespersen, Thomas, 5 Jul 2015, In: European Journal of Pharmacology. 758, p. 164-170 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    102. Published

      Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

      Axelsen, L. N., Callø, Kirstine, Braunstein, T. H., Riemann, Mads, Hofgaard, J. P., Liang, B., Jensen, C. F., Olsen, Kristine Boisen, Bartels, Emil Daniel, Baandrup, U., Jespersen, Thomas, Nielsen, L. B., von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, 14 Jul 2015, In: Cardiovascular Diabetology. 14, 14 p., 87.

      Research output: Contribution to journal › Journal article › Research › peer-review

    103. Published

      Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

      Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    104. Published

      Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms

      Tang, C., Skibsbye, L., Yuan, L., Bentzen, Bo Hjorth & Jespersen, Thomas, Oct 2015, In: General Physiology and Biophysics. 34, 4, p. 383-92 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    105. 2016
    106. Published

      The arrhythmogenic calmodulin mutation D129G dysregulates cell growth, calmodulin-dependent kinase II activity, and cardiac function in zebrafish

      Berchtold, Martin Werner, Zacharias, T., Kulej, K., Wang, K., Torggler, R., Jespersen, Thomas, Chen, J. N., Larsen, M. R. & la Cour, J. M., 2016, In: Journal of Biological Chemistry. 291, 52, p. 26636-26646 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    107. Published

      Pharmacological exploration of the resting membrane potential reserve: Impact on atrial fibrillation

      van der Heyden, M. A. G. & Jespersen, Thomas, 15 Jan 2016, In: European Journal of Pharmacology. 771, p. 56-64 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    108. Published

      Pharmacological inhibition of I-K1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness

      Skarsfeldt, M. A., Carstensen, Helena, Skibsbye, L., Tang, C., Buhl, Rikke, Bentzen, Bo Hjorth & Jespersen, Thomas, Apr 2016, In: Physiological Reports. 4, 8, 11 p., e12734.

      Research output: Contribution to journal › Journal article › Research › peer-review

    109. Published

      Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation

      Kirchhoff, J. E., Diness, Jonas Goldin, Abildgaard, L., Sheykhzade, Majid, Grunnet, Morten & Jespersen, Thomas, 8 Oct 2016, In: Pfluegers Archiv. 468, 11, p. 1853–1863 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    110. Published

      Refractoriness in human atria: Time and voltage dependence of sodium channel availability

      Skibsbye, L., Jespersen, Thomas, Christ, T., Maleckar, M. M., van den Brink, J., Tavi, P. & Koivumäki, J. T., Dec 2016, In: Journal of Molecular and Cellular Cardiology. 101, p. 26-34 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    111. 2017
    112. Published

      Kv3.1/Kv3.2 channel positive modulators enable faster activating kinetics and increase firing frequency in fast-spiking GABAergic interneurons

      Boddum, K., Hougaard, C., Xiao-Ying Lin, J., von Schoubye, N. L., Jensen, H. S., Grunnet, M. & Jespersen, Thomas, 2017, In: Neuropharmacology. 118, p. 102-112 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    113. Published

      Kredsløbet ændres ved overvægt i barndommen

      Lund, Morten Asp Vonsild, Holm, Jens-Christian, Jespersen, Thomas & von Holstein-Rathlou, Niels-Henrik, 2017, In: Ugeskrift for Laeger. 2018, 6, p. 2-6 5 p., V03170265.

      Research output: Contribution to journal › Journal article › Research › peer-review

    114. Published

      Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia

      Hyltén-Cavallius, L., Iepsen, E. W., Albrechtsen, Nicolai Jacob Wewer, Svendstrup, M., Lubberding, Anniek Frederike, Hartmann, Bolette, Jespersen, Thomas, Linneberg, Allan René, Christiansen, M., drb459, drb459, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K., Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Circulation. 135, 18, p. 1705-1719 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    115. Published

      Stability of Circulating Blood-Based MicroRNAs - Pre-Analytic Methodological Considerations

      Glinge, C., Clauss, S., Boddum, K., Jabbari, R., Jabbari, J., Risgaard, B., Tomsits, P., Hildebrand, B., Kääb, S., Wakili, R., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2017, In: PLOS ONE. 12, 2, 16 p., e0167969.

      Research output: Contribution to journal › Journal article › Research › peer-review

    116. Published

      Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts

      Hoeker, G. S., Skarsfeldt, M. A., Jespersen, Thomas & Poelzing, S., Jan 2017, In: Physiological Reports. 5, 1, 10 p., e13120.

      Research output: Contribution to journal › Journal article › Research › peer-review

    117. Published

      A Multiple Kernel Learning Framework to Investigate the Relationship Between Ventricular Fibrillation and First Myocardial Infarction

      Marciniak, M., Arevalo, H., Tfelt-Hansen, Jacob, Ahtarovski, K. A., Jespersen, Thomas, Jabbari, R., Glinge, C., Vejlstrup, N., Engstrøm, Thomas, Maleckar, M. M. & McLeod, K., 1 Jan 2017, Functional Imaging and Modelling of the Heart: 9th International Conference, FIMH 2017, Toronto, ON, Canada, June 11-13, 2017, Proceedings. Springer, p. 161-171 11 p. (Lecture Notes in Computer Science, Vol. 10263 LNCS).

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

    118. Published

      From CMR Image to Patient-Specific Simulation and Population-Based Analysis: Tutorial for an Openly Available Image-Processing Pipeline

      Marciniak, M., Arevalo, H., Tfelt-Hansen, Jacob, Jespersen, Thomas, Jabbari, R., Glinge, C., Ahtarovski, K. A., Vejlstrup, N., Engstrøm, Thomas, Maleckar, M. M. & McLeod, K., 1 Jan 2017, Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges - 7th International Workshop, STACOM 2016 Held in Conjunction with MICCAI 2016, Revised Selected Papers. Springer, p. 106-117 12 p. (Lecture Notes in Computer Science, Vol. 10124 LNCS).

      Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

    119. Published

      Pharmacological blockade of small conductance Ca-activated K channels by ICA reduces arrhythmic load in rats with acute myocardial infarction

      Hundahl, L. A., Sattler, S. M., Skibsbye, L., Diness, J. G., Tfelt-Hansen, Jacob & Jespersen, Thomas, Jun 2017, In: Pflügers Archiv - European Journal of Physiology. 469, 5-6, p. 739-750 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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