Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts

Research output: Contribution to journalJournal articleResearchpeer-review

Cardiac arrhythmia is a potentially lethal condition. A better prediction and mechanistic understanding of human cardiac arrhythmia is dependent on the development of good animal models. Minipigs are increasingly being used in cardiovascular research and we hypothesize that Langendorff-perfused minipig hearts could serve as a novel model of pro-arrhythmia.
Original languageEnglish
JournalJournal of Pharmacological and Toxicological Methods
Volume64
Issue number2
Pages (from-to)134-44
Number of pages11
ISSN1056-8719
DOIs
Publication statusPublished - 2012

    Research areas

  • Adrenergic beta-Agonists, Animals, Arrhythmias, Cardiac, Atrioventricular Block, Disease Models, Animal, Dogs, Electric Stimulation, Electrocardiography, Female, Isoproterenol, Species Specificity, Swine, Swine, Miniature

ID: 40472426