Michael Jonathan Davies
Michael Jonathan Davies

Professor


  1. Photo-oxidation of proteins

    Pattison, D. I., Rahmanto, A. S. & Davies, Michael Jonathan, Jan 2012, In : Photochemical & Photobiological Sciences. 11, 1, p. 38-53 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Photo-oxidation of cells generates long-lived intracellular protein peroxides

    Wright, A., Hawkins, Clare Louise & Davies, Michael Jonathan, 15 Mar 2003, In : Free Radical Biology & Medicine. 34, 6, p. 637-47 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal

    Morgan, P. E., Sheahan, P. J. & Davies, Michael Jonathan, 2014, In : PloS one. 9, 1, 11 p., e86564.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. E-pub ahead of print

    Personalized nutrition in ageing society: redox control of major-age related diseases through the NutRedOx Network (COST Action CA16112)

    Tur, J. A., Jacob, C., Chaimbault, P., Tadayyon, M., Richling, E., Hermans, N., dos Santos, C. N., Diederich, M., Giblin, L., Elhabiri, M., Gaucher, C., Andreoletti, P., Fernandes, A., Davies, Michael Jonathan, Bartoszek, A. & Cherkaoui-Malki, M., 2019, In : Free Radical Research.

    Research output: Contribution to journalEditorialResearchpeer-review

  5. Published

    Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin

    Degendorfer, G., Chuang, Christine, Hammer, A., Malle, E. & Davies, Michael Jonathan, Dec 2015, In : Free Radical Biology & Medicine. 89, p. 721-733 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Peroxynitrite-mediated oxidation of plasma fibronectin

    Degendorfer, G., Chuang, Christine, Kawasaki, H., Hammer, A., Malle, E., Yamakura, F. & Davies, Michael Jonathan, Aug 2016, In : Free Radical Biology & Medicine. 97, p. 602-615 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains

    Kennett, E. C., Rees, M. D., Malle, E., Hammer, A., Whitelock, J. M. & Davies, Michael Jonathan, 15 Jul 2010, In : Free Radical Biology & Medicine. 49, 2, p. 282-93 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Peroxyl radicals induce oxidative crosslinking of superoxide dismutase 1 through self-reaction of protein radicals [Meeting Abstract]

    Escobar, E., Fuentes-Lemus, E., Figueroa, J. D., Fuentealba, D., Denicola, A., Alvarez, B., Leinisch, F., Davies, Michael Jonathan & Lopez-Alarcon, C., 2019, In : Free Radical Biology and Medicine. 139, S1, p. S21-S21 53.

    Research output: Contribution to journalConference articleResearch

  9. Published

    Peroxyl radical- and photo-oxidation of glucose 6-phosphate dehydrogenase generates cross-links and functional changes via oxidation of tyrosine and tryptophan residues

    Leinisch, F., Mariotti, M., Rykaer, M., López-Alarcón, C., Hägglund, P. & Davies, Michael Jonathan, Nov 2017, In : Free Radical Biology & Medicine. 112, p. 240-252 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima

    Mai, K., Smith, N. C., Feng, Z., Katrib, M., Slapeta, J., Slapetova, I., Wallach, M. G., Luxford, C., Davies, Michael Jonathan, Zhang, X., Norton, R. S. & Belli, S. I., Sep 2011, In : International Journal for Parasitology (Online). 41, 11, p. 1157-64 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Oxidative damage to extracellular matrix and its role in human pathologies

    Rees, M. D., Kennett, E. C., Whitelock, J. M. & Davies, Michael Jonathan, 15 Jun 2008, In : Free Radical Biology & Medicine. 44, 12, p. 1973-2001 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Oxidative damage to collagen and related substrates by metal ion/hydrogen peroxide systems: random attack or site-specific damage?

    Hawkins, C. L. & Davies, Michael Jonathan, 27 Feb 1997, In : B B A - Reviews on Cancer. 1360, 1, p. 84-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Oxidation of myosin by haem proteins generates myosin radicals and protein cross-links

    Lund, Marianne N., Luxford, C., Skibsted, Leif Horsfelt & Davies, Michael Jonathan, 2008, In : Biochemical Journal. 410, 3, p. 565-574 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Oxidation of human plasma fibronectin by inflammatory oxidants perturbs endothelial cell function

    Vanichkitrungruang, S., Chuang, Christine, Hawkins, Clare Louise, Hammer, A., Hoefler, G., Malle, E. & Davies, Michael Jonathan, 2019, In : Free Radical Biology and Medicine. 136, p. 118-134

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation

    Rees, M. D., Pattison, D. I. & Davies, Michael Jonathan, 1 Oct 2005, In : Biochemical Journal. 391, Pt 1, p. 125-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Oxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals

    Fuentes-Lemus, E., Dorta, E., Escobar, E., Aspee, A., Pino, E., Abasq, M. L., Speisky, H., Silva, E., Lissi, E., Davies, Michael Jonathan & Lopez-Alarcon, C., 2016, In : RSC Advances. 6, 63, p. 57948-57955 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s

    Pattison, D. I., Dean, R. T. & Davies, Michael Jonathan, 1 Aug 2002, In : Toxicology. 177, 1, p. 23-37 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells

    Chuang, Christine, Degendorfer, G., Hammer, A., Whitelock, J. M., Malle, E. & Davies, Michael Jonathan, 15 Apr 2014, In : Biochemical Journal. 459, 2, p. 313-22 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Oxidation and modification of extracellular matrix and its role in disease

    Chuang, Christine, Degendorfer, G. & Davies, Michael Jonathan, Sep 2014, In : Free Radical Research. 48, 9, p. 970-89 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides

    Dremina, E. S., Sharov, V. S., Davies, Michael Jonathan & Schöneich, C., Oct 2007, In : Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Oxidation and antioxidation of human low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite

    Thomas, S. R., Davies, Michael Jonathan & Stocker, R., 1998, In : Chemical Research in Toxicology. 11, 5, p. 484-94 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. One-electron reduction of N-chlorinated and N-brominated species is a source of radicals and bromine atom formation

    Pattison, D. I., O'Reilly, R. J., Skaff, O., Radom, L., Anderson, R. F. & Davies, Michael Jonathan, 21 Mar 2011, In : Chemical Research in Toxicology. 24, 3, p. 371-82 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Novel monohydroxamate drugs attenuate myocardial reperfusion-induced arrhythmias

    Collis, C. S., Rice-Evans, C. & Davies, Michael Jonathan, Apr 1996, In : International Journal of Biochemistry & Cell Biology. 28, 4, p. 405-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I

    Nobécourt, E., Tabet, F., Lambert, G., Puranik, R., Bao, S., Yan, L., Davies, Michael Jonathan, Brown, B. E., Jenkins, A. J., Dusting, G. J., Bonnet, D. J., Curtiss, L. K., Barter, P. J. & Rye, K., Apr 2010, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 4, p. 766-72 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Nitric oxide and nitroxides can act as efficient scavengers of protein-derived free radicals

    Lam, M. A., Pattison, D. I., Bottle, S. E., Keddie, D. J. & Davies, Michael Jonathan, Nov 2008, In : Chemical Research in Toxicology. 21, 11, p. 2111-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Nitration alters laminin polymerization: [Meeting Abstract]

    Lorentzen, Lasse Gøbel & Davies, Michael Jonathan, 2018, In : Free Radical Biology and Medicine. 120, S1, p. S127-S127 P-271.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  27. Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers

    Birinyi-Strachan, L. C., Davies, Michael Jonathan, Lewis, R. J. & Nicholson, G. M., Oct 2005, In : Neuropharmacology. 49, 5, p. 669-86 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Myoglobin-induced oxidative damage: evidence for radical transfer from oxidized myoglobin to other proteins and antioxidants

    Irwin, J. A., Ostdal, H. & Davies, Michael Jonathan, 1 Feb 1999, In : Archives of Biochemistry and Biophysics. 362, 1, p. 94-104 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention

    Davies, Michael Jonathan, Jan 2011, In : Journal of Clinical Biochemistry and Nutrition. 48, 1, p. 8-19 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan

    Rees, M. D., Whitelock, J. M., Malle, E., Chuang, Christine, Iozzo, R. V., Nilasaroya, A. & Davies, Michael Jonathan, Jan 2010, In : Matrix Biology. 29, 1, p. 63-73 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Myeloperoxidase-derived oxidants rapidly oxidize and disrupt zinc-cysteine/histidine clusters in proteins

    Cook, N. L., Pattison, D. I. & Davies, Michael Jonathan, 1 Dec 2012, In : Free Radical Biology & Medicine. 53, 11, p. 2072-80 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)

    Hadfield, K. A., Pattison, D. I., Brown, B. E., Hou, L., Rye, K., Davies, Michael Jonathan & Hawkins, Clare Louise, 15 Jan 2013, In : Biochemical Journal. 449, 2, p. 531-42 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells

    Cook, N. L., Viola, H. M., Sharov, V. S., Hool, L. C., Schöneich, C. & Davies, Michael Jonathan, 1 Mar 2012, In : Free Radical Biology & Medicine. 52, 5, p. 951-61 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: The Microalbuminuria Education and Medication Optimisation (MEMO) study

    Crasto, W., Jarvis, J., Khunti, K., Skinner, Timothy, Gray, L. J., Brela, J., Troughton, J., Daly, H., Lawrence, I. G., McNally, P. G., Carey, M. E. & Davies, Michael Jonathan, 1 Sep 2011, In : Diabetes Research and Clinical Practice. 93, 3, p. 328-336 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Modulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy

    Sourris, K. C., Harcourt, B. E., Penfold, S. A., Yap, F. Y. T., Morley, A. L., Morgan, P. E., Davies, Michael Jonathan, Baker, S. T., Jerums, G. & Forbes, J. M., 2010, In : Journal of Diabetes Research. 2010, p. 974681

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Modification of the extracellular matrix of the arterial wall by myeloperoxidase contributes to atherosclerosis: [Meeting Absract]

    Cai, Huan, Chuang, Christine & Davies, Michael Jonathan, 2018, In : International Journal of Experimental Pathology. 99, 6, p. A24-A24

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  37. Published

    Modification of selenocysteine residues in thioredoxin reductase and glutathione peroxidase by p-benzoquinone affects protein structure and function: [Meeting Abstract]

    Shu, N. & Davies, Michael Jonathan, 1 Aug 2019, In : Free Radical Biology and Medicine. 139, S1, p. S49-S49 168.

    Research output: Contribution to journalConference articleResearch

  38. Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid

    Malle, E., Marsche, G., Arnhold, J. & Davies, Michael Jonathan, Apr 2006, In : B B A - Reviews on Cancer. 1761, 4, p. 392-415 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Modification of Cys residues in thioredoxin by p-benzoquinone causes inhibition of its catalytic activity and activation of ASK1/p38-MAPK signalling pathway: [Meeting Abstract]

    Shu, N., Hägglund, Per Mårten & Davies, Michael Jonathan, 1 Aug 2019, In : Free Radical Biology and Medicine. 139, S1, p. S9-S9 8.

    Research output: Contribution to journalConference articleResearch

  40. Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes

    Morgan, P. E., Sheahan, P. J., Pattison, D. I. & Davies, Michael Jonathan, Aug 2013, In : Free Radical Biology & Medicine. 61, p. 229-42 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Mechanistic view of iodide in oxidative stress: [Meeting Abstract]

    Kciuk, M. I., Davies, Michael Jonathan & Marciniak, B., 2018, In : Free Radical Biology and Medicine. 120, S1, p. S122-S122 P-254.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  42. Mechanisms of degradation of the natural high-potency sweetener (2R,4R)-monatin in mock beverage solutions

    Storkey, C., Pattison, D. I., Gaspard, D. S., Hagestuen, E. D. & Davies, Michael Jonathan, 16 Apr 2014, In : Journal of Agricultural and Food Chemistry. 62, 15, p. 3476-87 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Mechanisms and consequences of oxidative damage to extracellular matrix

    Kennett, E. C., Chuang, Christine, Degendorfer, G., Whitelock, J. M. & Davies, Michael Jonathan, Oct 2011, In : Biochemical Society Transactions. 39, 5, p. 1279-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Mass-Spectrometry-Based Identification of Cross-Links in Proteins Exposed to Photo-Oxidation and Peroxyl Radicals Using 18O Labeling and Optimized Tandem Mass Spectrometry Fragmentation

    Mariotti, Michele, Leinisch, F., Leeming, D. J., Svensson, B., Davies, Michael Jonathan & Hägglund, Per Mårten, 2018, In : Journal of Proteome Research. 17, 6, p. 2017-2027

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products

    Headlam, H. A. & Davies, Michael Jonathan, 2004, In : Free Radical Biology & Medicine. 36, 9, p. 1175-84 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin and enhances rat gastric tumor cell invasion

    Indo, H. P., Matsui, H., Chen, J., Zhu, H., Hawkins, Clare Louise, Davies, Michael Jonathan, Yarana, C., Clair, D. K. S. & Majima, H. J., 1 Jul 2015, In : Journal of Clinical Biochemistry and Nutrition. 57, 1, p. 13-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Mammalian heme peroxidases: from molecular mechanisms to health implications

    Davies, Michael Jonathan, Hawkins, Clare Louise, Pattison, D. I. & Rees, M. D., Jul 2008, In : Antioxidants & Redox Signaling. 10, 7, p. 1199-234 36 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Low zinc and selenium concentrations in sepsis are associated with oxidative damage and inflammation

    Mertens, K., Lowes, D. A., Webster, N. R., Talib, J., Hall, L., Davies, Michael Jonathan, Beattie, J. H. & Galley, H. F., 2015, In : British Journal of Anaesthesia. 114, 6, p. 990-999 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Lipid oxidation in human low-density lipoprotein induced by metmyoglobin/H2O2: involvement of alpha-tocopheroxyl and phosphatidylcholine alkoxyl radicals

    Witting, P. K., Willhite, C. A., Davies, Michael Jonathan & Stocker, R., Dec 1999, In : Chemical Research in Toxicology. 12, 12, p. 1173-81 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Leghemoglobin-derived radicals. Evidence for multiple protein-derived radicals and the initiation of peribacteroid membrane damage

    Moreau, S., Davies, Michael Jonathan, Mathieu, C., Hérouart, D. & Puppo, A., 20 Dec 1996, In : The Journal of Biological Chemistry. 271, 51, p. 32557-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 38036205