Michael J. Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
- 2008
Identification of plasma proteins that are susceptible to thiol oxidation by hypochlorous acid and N-chloramines
Summers, F. A., Morgan, P. E., Davies, Michael J. & Hawkins, Clare Louise, Sep 2008, In: Chemical Research in Toxicology. 21, 9, p. 1832-40 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypochlorous acid oxidizes methionine and tryptophan residues in myoglobin
Szuchman-Sapir, A. J., Pattison, D. I., Ellis, N. A., Hawkins, Clare Louise, Davies, Michael J. & Witting, P. K., 15 Sep 2008, In: Free Radical Biology & Medicine. 45, 6, p. 789-98 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Waiting for diabetes: Perceptions of people with pre-diabetes: A qualitative study
Troughton, J., Jarvis, J., Skinner, Timothy, Robertson, N., Khunti, K. & Davies, Michael J., 1 Jul 2008, In: Patient Education and Counseling. 72, 1, p. 88-93 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages
Brown, B. E., Rashid, I., van Reyk, D. M. & Davies, Michael J., Mar 2007, In: F E B S Journal. 274, 6, p. 1530-41 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation and inactivation of SERCA by selective reaction of cysteine residues with amino acid peroxides
Dremina, E. S., Sharov, V. S., Davies, Michael J. & Schöneich, C., Oct 2007, In: Chemical Research in Toxicology. 20, 10, p. 1462-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products
Gracanin, M. & Davies, Michael J., 15 May 2007, In: Free Radical Biology & Medicine. 42, 10, p. 1543-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Degradation of matrix glycosaminoglycans by peroxynitrite/peroxynitrous acid: evidence for a hydroxyl-radical-like mechanism
Kennett, E. C. & Davies, Michael J., 15 Apr 2007, In: Free Radical Biology & Medicine. 42, 8, p. 1278-89 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis
Morgan, P. E., Sturgess, A. D., Hennessy, A. & Davies, Michael J., Dec 2007, In: Free Radical Research. 41, 12, p. 1301-12 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of glycation on apolipoprotein A-I structure and its ability to activate lecithin: cholesterol acyltransferase
Nobecourt, E., Davies, Michael J., Brown, B. E., Curtiss, L. K., Bonnet, D. J., Charlton, F., Januszewski, A. S., Jenkins, A. J., Barter, P. J. & Rye, K. -., Mar 2007, In: Diabetologia. 50, 3, p. 643-653 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses
Parker, N. R., Korlimbinis, A., Jamie, J. F., Davies, Michael J. & Truscott, R. J. W., Aug 2007, In: Investigative Ophthalmology & Visual Science. 48, 8, p. 3705-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., 28 Aug 2007, In: Biochemistry. 46, 34, p. 9853-64 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro
Rashid, I., van Reyk, D. M. & Davies, Michael J., 6 Mar 2007, In: FEBS Letters. 581, 5, p. 1067-70 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Degradation of extracellular matrix and its components by hypobromous acid
Rees, M. D., McNiven, T. N. & Davies, Michael J., 15 Jan 2007, In: Biochemical Journal. 401, 2, p. 587-96 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Kinetics of hypobromous acid-mediated oxidation of lipid components and antioxidants
Skaff, O., Pattison, D. I. & Davies, Michael J., Dec 2007, In: Chemical Research in Toxicology. 20, 12, p. 1980-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
Sensitizer-mediated photooxidation of histidine residues: evidence for the formation of reactive side-chain peroxides
Agon, V. V., Bubb, W. A., Wright, A., Hawkins, Clare Louise & Davies, Michael J., 15 Feb 2006, In: Free Radical Biology & Medicine. 40, 4, p. 698-710 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides
Headlam, H. A., Gracanin, M., Rodgers, K. J. & Davies, Michael J., 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid
Malle, E., Marsche, G., Arnhold, J. & Davies, Michael J., Apr 2006, In: B B A - Reviews on Cancer. 1761, 4, p. 392-415 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
Reactions of myeloperoxidase-derived oxidants with biological substrates: Gaining chemical insight into human inflammatory diseases
Pattison, David & Davies, Michael J., 2006, In: Current Medicinal Chemistry. 13, 27, p. 3271-3290 20 p.Research output: Contribution to journal › Review › Research › peer-review
Actions of ultraviolet light on cellular structures
Pattison, D. I. & Davies, Michael J., 2006, In: E X S. 96, p. 131-57 27 p.Research output: Contribution to journal › Journal article › Research
Evidence for rapid inter- and intramolecular chlorine transfer reactions of histamine and carnosine chloramines: implications for the prevention of hypochlorous-acid-mediated damage
Pattison, D. I. & Davies, Michael J., 4 Jul 2006, In: Biochemistry. 45, 26, p. 8152-62 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Heparan sulfate degradation via reductive homolysis of its N-chloro derivatives
Rees, M. D. & Davies, Michael J., 8 Mar 2006, In: Journal of the American Chemical Society. 128, 9, p. 3085-97 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes education and self-management for ongoing and newly diagnosed (DESMOND): Process modelling of pilot study
Skinner, Timothy, Carey, M. E., Cradock, S., Daly, H., Davies, Michael J., Doherty, Y., Heller, S., Khunti, K. & Oliver, L., 1 Dec 2006, In: Patient Education and Counseling. 64, 1-3, p. 369-377 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions
Stanley, N., Stadler, N., Bannon, P. G., Woods, A. A. & Davies, Michael J., 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1636-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effect of side chains on competing pathways for beta-scission reactions of peptide-backbone alkoxyl radicals
Wood, G. P. F., Easton, C. J., Rauk, A., Davies, Michael J. & Radom, L., 31 Aug 2006, In: Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory. 110, 34, p. 10316-23 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols
Zeng, J., Dunlop, R. A., Rodgers, K. J. & Davies, Michael J., 1 Sep 2006, In: Biochemical Journal. 398, 2, p. 197-206 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein and low molecular mass thiols as targets and inhibitors of glycation reactions
Zeng, J. & Davies, Michael J., Dec 2006, In: Chemical Research in Toxicology. 19, 12, p. 1668-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers
Birinyi-Strachan, L. C., Davies, Michael J., Lewis, R. J. & Nicholson, G. M., Oct 2005, In: Neuropharmacology. 49, 5, p. 669-86 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells
Brown, B. E., Dean, R. T. & Davies, Michael J., Feb 2005, In: Diabetologia. 48, 2, p. 361-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The oxidative environment and protein damage
Davies, Michael J., 17 Jan 2005, In: B B A - Reviews on Cancer. 1703, 2, p. 93-109 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Guanine-specific DNA damage induced by gamma-irradiated histone
Furukawa, A., Hiraku, Y., Oikawa, S., Luxford, C., Davies, Michael J. & Kawanishi, S., 15 Jun 2005, In: Biochemical Journal. 388, Pt 3, p. 813-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function
Hawkins, Clare Louise & Davies, Michael J., Oct 2005, In: Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme
Hawkins, Clare Louise & Davies, Michael J., Nov 2005, In: Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation
Hawkins, Clare Louise & Davies, Michael J., 1 Oct 2005, In: Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The illness beliefs of people newly diagnosed with type 2 diabetes: results from the DESMOND pilot study
Heller, S., Davies, Michael J., Khunti, K., Skinner, Timothy & James, P., 1 Jan 2005, Diabetologia.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus
Morgan, P. E., Sturgess, A. D. & Davies, Michael J., Jul 2005, In: Arthritis & Rheumatism. 52, 7, p. 2069-79 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation
Pattison, D. I. & Davies, Michael J., 17 May 2005, In: Biochemistry. 44, 19, p. 7378-87 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Oxidation of heparan sulphate by hypochlorite: role of N-chloro derivatives and dichloramine-dependent fragmentation
Rees, M. D., Pattison, D. I. & Davies, Michael J., 1 Oct 2005, In: Biochemical Journal. 391, Pt 1, p. 125-34 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein oxidation injury occurs during pediatric cardiopulmonary bypass
Sheil, M. L., Luxford, C., Davies, Michael J., Peat, J. K., Nunn, G. & Celermajer, D. S., Oct 2005, In: Journal of Thoracic and Cardiovascular Surgery. 130, 4, p. 1054-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes screening anxiety and beliefs
Skinner, Timothy, Davies, Michael J., Farooqi, A. M., Jarvis, J., Tringham, J. R. & Khunti, K., 1 Nov 2005, In: Diabetic Medicine. 22, 11, p. 1497-1502 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Utility of risk factors when screening for diabetes mellitus
Tringham, J. R., Davies, Michael J., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Jan 2005, Diabetes.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins
Zeng, J. & Davies, Michael J., Aug 2005, In: Chemical Research in Toxicology. 18, 8, p. 1232-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
EPR spin trapping of protein radicals
Davies, Michael J. & Hawkins, Clare Louise, 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1072-86 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reactive species formed on proteins exposed to singlet oxygen
Davies, Michael J., Jan 2004, In: Photochemical & Photobiological Sciences. 3, 1, p. 17-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products
Headlam, H. A. & Davies, Michael J., 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protective mechanisms against peptide and protein peroxides generated by singlet oxygen
Morgan, P. E., Dean, R. T. & Davies, Michael J., 15 Feb 2004, In: Free Radical Biology & Medicine. 36, 4, p. 484-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein-bound kynurenine is a photosensitizer of oxidative damage
Parker, N. R., Jamie, J. F., Davies, Michael J. & Truscott, R. J. W., 1 Nov 2004, In: Free Radical Biology & Medicine. 37, 9, p. 1479-89 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress
Pattison, D. I. & Davies, Michael J., 27 Apr 2004, In: Biochemistry. 43, 16, p. 4799-809 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite and superoxide radicals can act synergistically to induce fragmentation of hyaluronan and chondroitin sulphates
Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper
Stadler, N., Lindner, R. A. & Davies, Michael J., 2004, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 24, 5, p. 949-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides
Winterbourn, C. C., Parsons-Mair, H. N., Gebicki, S., Gebicki, J. M. & Davies, Michael J., 1 Jul 2004, In: Biochemical Journal. 381, Pt 1, p. 241-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Roles of tyrosine-rich precursor glycoproteins and dityrosine- and 3,4-dihydroxyphenylalanine-mediated protein cross-linking in development of the oocyst wall in the coccidian parasite Eimeria maxima
Belli, S. I., Wallach, M. G., Luxford, C., Davies, Michael J. & Smith, N. C., Jun 2003, In: Eukaryotic Cell (Online Edition). 2, 3, p. 456-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Singlet oxygen-mediated damage to proteins and its consequences
Davies, Michael J., 6 Jun 2003, In: Molecular Cell Biology Research Communications. 305, 3, p. 761-70 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radical chemistry of epigallocatechin gallate and its relevance to protein damage
Hagerman, A. E., Dean, R. T. & Davies, Michael J., 1 Jun 2003, In: Nitric Oxide: Biology and Chemistry. 414, 1, p. 115-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced oxidation of amino acids, peptides and proteins
Hawkins, C. L., Pattison, D. I. & Davies, Michael J., Dec 2003, In: Amino Acids. 25, 3-4, p. 259-74 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell-mediated reduction of protein and peptide hydroperoxides to reactive free radicals
Headlam, H. A. & Davies, Michael J., 1 Jan 2003, In: Free Radical Biology & Medicine. 34, 1, p. 44-55 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles
Knott, H. M., Brown, B. E., Davies, Michael J. & Dean, R. T., Sep 2003, In: European Journal of Biochemistry. 270, 17, p. 3572-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorous acid-mediated oxidation of lipid components and antioxidants present in low-density lipoproteins: absolute rate constants, product analysis, and computational modeling
Pattison, D. I., Hawkins, Clare Louise & Davies, Michael J., Apr 2003, In: Chemical Research in Toxicology. 16, 4, p. 439-49 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-mediated fragmentation of hyaluronan, chondroitin sulfates, and related N-acetyl glycosamines: evidence for chloramide intermediates, free radical transfer reactions, and site-specific fragmentation
Rees, M. D., Hawkins, Clare Louise & Davies, Michael J., 12 Nov 2003, In: Journal of the American Chemical Society. 125, 45, p. 13719-33 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques
Woods, A. A., Linton, S. M. & Davies, Michael J., 1 Mar 2003, In: Biochemical Journal. 370, Pt 2, p. 729-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fragmentation of extracellular matrix by hypochlorous acid
Woods, A. A. & Davies, Michael J., 15 Nov 2003, In: Biochemical Journal. 376, Pt 1, p. 219-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Photo-oxidation of cells generates long-lived intracellular protein peroxides
Wright, A., Hawkins, Clare Louise & Davies, Michael J., 15 Mar 2003, In: Free Radical Biology & Medicine. 34, 6, p. 637-47 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The retina: oxidative stress and diabetes
van Reyk, D. M., Gillies, M. C. & Davies, Michael J., 2003, In: Redox Report (Online). 8, 4, p. 187-92 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides
Hampton, M. B., Morgan, P. E. & Davies, Michael J., 11 Sep 2002, In: FEBS Letters. 527, 1-3, p. 289-92 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals
Hawkins, Clare Louise & Davies, Michael J., Jan 2002, In: Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation
Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael J., 1 Aug 2002, In: Biochemical Journal. 365, Pt 3, p. 605-15 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins
Hawkins, Clare Louise, Rees, M. D. & Davies, Michael J., 2 Jan 2002, In: FEBS Letters. 510, 1-2, p. 41-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones
Headlam, H. A. & Davies, Michael J., 1 Jun 2002, In: Free Radical Biology & Medicine. 32, 11, p. 1171-84 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein
Knott, H. M., Baoutina, A., Davies, Michael J. & Dean, R. T., 15 Apr 2002, In: Archives of Biochemistry and Biophysics. 400, 2, p. 223-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of DNA damage by oxidised amino acids and proteins
Luxford, C., Dean, R. T. & Davies, Michael J., 2002, In: Biogerontology. 3, 1-2, p. 95-102 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products
Morgan, P. E., Dean, R. T. & Davies, Michael J., 15 Jul 2002, In: Archives of Biochemistry and Biophysics. 403, 2, p. 259-69 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack
Morgan, P. E., Dean, R. T. & Davies, Michael J., Apr 2002, In: European Journal of Biochemistry. 269, 7, p. 1916-25 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of aliphatic amino acid alcohols in oxidized proteins
Morin, B., Fu, S., Wang, H., Davies, Michael J. & Dean, R. T., 2002, In: Methods in molecular biology (Clifton, N.J.). 186, p. 101-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s
Pattison, D. I., Dean, R. T. & Davies, Michael J., 1 Aug 2002, In: Toxicology. 177, 1, p. 23-37 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive side chain peroxides on tyrosine residues
Wright, A., Bubb, W. A., Hawkins, Clare Louise & Davies, Michael J., Jul 2002, In: Photochemistry and Photobiology. 76, 1, p. 35-46 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reaction between protein radicals and other biomolecules
Østdal, H., Davies, Michael J. & Andersen, H. J., 15 Jul 2002, In: Free Radical Biology & Medicine. 33, 2, p. 201-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Photo-oxidation of proteins and its role in cataractogenesis
Davies, Michael J. & Truscott, R. J., 2001, In: Journal of Photochemistry and Photobiology, B: Biology. 63, 1-3, p. 114-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Generation and propagation of radical reactions on proteins
Hawkins, C. L. & Davies, Michael J., 2 Apr 2001, In: B B A - Reviews on Cancer. 1504, 2-3, p. 196-219 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis
Hawkins, C. L., Brown, B. E. & Davies, Michael J., 15 Nov 2001, In: Archives of Biochemistry and Biophysics. 395, 2, p. 137-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals
Hawkins, C. L. & Davies, Michael J., Aug 2001, In: Chemical Research in Toxicology. 14, 8, p. 1071-81 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein oxidation and ageing
Linton, S., Davies, Michael J. & Dean, R. T., Sep 2001, In: Experimental Gerontology. 36, 9, p. 1503-18 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absolute rate constants for the reaction of hypochlorous acid with protein side chains and peptide bonds
Pattison, D. I. & Davies, Michael J., 2001, In: Chemical Research in Toxicology. 14, 10, p. 1453-64 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An investigation of the chromium oxidation state of a monoanionic chromium tris(catecholate) complex by X-ray absorption and EPR spectroscopies
Pattison, D. I., Levina, A., Davies, Michael J. & Lay, P. A., 15 Jan 2001, In: Inorganic Chemistry. 40, 2, p. 214-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: relevance to chromium genotoxicity
Pattison, D. I., Davies, Michael J., Levina, A., Dixon, N. E. & Lay, P. A., 2001, In: Chemical Research in Toxicology. 14, 5, p. 500-10 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates
Davies, Michael J. & Hawkins, C. L., Dec 2000, In: Free Radical Research. 33, 6, p. 719-29 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract
Garner, B., Davies, Michael J. & Truscott, R. J., Jan 2000, In: Experimental Eye Research. 70, 1, p. 81-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced damage to red blood cells: evidence for the formation of nitrogen-centred radicals
Hawkins, C. L. & Davies, Michael J., 2000, In: Redox Report (Online). 5, 1, p. 57-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
beta-Scission of C-3 (beta-carbon) alkoxyl radicals on peptides and proteins: a novel pathway which results in the formation of alpha-carbon radicals and the loss of amino acid side chains
Headlam, H. A., Mortimer, A., Easton, C. J. & Davies, Michael J., Nov 2000, In: Chemical Research in Toxicology. 13, 11, p. 1087-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA
Luxford, C., Dean, R. T. & Davies, Michael J., Jul 2000, In: Chemical Research in Toxicology. 13, 7, p. 665-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An investigation into the genotoxic species generated during reduction of chromium(VI) by catechol(amine)s
Pattison, D. I., Lay, P. A. & Davies, Michael J., 2000, In: Redox Report (Online). 5, 2-3, p. 130-2 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EPR studies of chromium(V) intermediates generated via reduction of chromium(VI) by DOPA and related catecholamines: potential role for oxidized amino acids in chromium-induced cancers
Pattison, D. I., Lay, P. A. & Davies, Michael J., 26 Jun 2000, In: Inorganic Chemistry. 39, 13, p. 2729-39 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive peroxides
Wright, A., Hawkins, C. L. & Davies, Michael J., 2000, In: Redox Report (Online). 5, 2-3, p. 159-61 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Stable markers of oxidant damage to proteins and their application in the study of human disease
Davies, Michael J., Fu, S., Wang, H. & Dean, R. T., Dec 1999, In: Free Radical Biology & Medicine. 27, 11-12, p. 1151-63 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation
Hawkins, C. L. & Davies, Michael J., 1 Jun 1999, In: Biochemical Journal. 340 ( Pt 2), p. 539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins
Hazell, L. J., Davies, Michael J. & Stocker, R., 1999, In: Biochemical Journal. 339 ( Pt 3), p. 489-95 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myoglobin-induced oxidative damage: evidence for radical transfer from oxidized myoglobin to other proteins and antioxidants
Irwin, J. A., Ostdal, H. & Davies, Michael J., 1 Feb 1999, In: Archives of Biochemistry and Biophysics. 362, 1, p. 94-104 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA
Luxford, C., Morin, B., Dean, R. T. & Davies, Michael J., 15 Nov 1999, In: Biochemical Journal. 344 Pt 1, p. 125-34 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation of long-lived radicals on proteins by radical transfer from heme enzymes--a common process?
Ostdal, H., Andersen, H. J. & Davies, Michael J., 1 Feb 1999, In: Archives of Biochemistry and Biophysics. 362, 1, p. 105-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipid oxidation in human low-density lipoprotein induced by metmyoglobin/H2O2: involvement of alpha-tocopheroxyl and phosphatidylcholine alkoxyl radicals
Witting, P. K., Willhite, C. A., Davies, Michael J. & Stocker, R., Dec 1999, In: Chemical Research in Toxicology. 12, 12, p. 1173-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque
Fu, S., Davies, Michael J., Stocker, R. & Dean, R. T., 1 Aug 1998, In: Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Degradation of hyaluronic acid, poly- and monosaccharides, and model compounds by hypochlorite: evidence for radical intermediates and fragmentation
Hawkins, C. L. & Davies, Michael J., Jun 1998, In: Free Radical Biology & Medicine. 24, 9, p. 1396-410 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
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