Mette Rosenkilde

Mette Rosenkilde

Professor

Member of:

    ORCID: 0000-0001-9600-3254

    Publication year:
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    176 - 200 out of 270Page size: 25
    1. 2014
    2. Published

      Gating function of isoleucine-116 in TM-3 (position III:16/3.40) for the activity state of the CC-chemokine receptor 5 (CCR5)

      Steen, A., wbf943, wbf943, Thiele, S., Guo, D., Frimurer, Thomas Michael & Rosenkilde, Mette, Mar 2014, In: British Journal of Pharmacology. 171, 6, p. 1566-79 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Biased and g protein-independent signaling of chemokine receptors

      Steen, A., Larsen, O., Thiele, S. & Rosenkilde, Mette, 2014, In: Frontiers in Immunology. 5, p. 1-13 13 p., 277.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Discovery and mapping of an intracellular antagonist binding site at the chemokine receptor CCR2

      Zweemer, A. J. M., Bunnik, J., Veenhuizen, M., Miraglia, F., Lenselink, E. B., Vilums, M., de Vries, H., Gibert, A., Thiele, S., Rosenkilde, Mette, IJzerman, A. P. & Heitman, L. H., 2014, In: Molecular Pharmacology. 86, 4, p. 358-68 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Functional properties of Virus-Encoded and Virus-Regulated 7TM Receptors

      Spiess, Katja & Rosenkilde, Mette, 2014, G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era. Stevens, C. W. (ed.). Humana Press, p. 45-64 20 p. (Methods in Pharmacology and Toxicology).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

    6. Published

      Interaction of chemokines with their receptors--from initial chemokine binding to receptor activating steps

      Thiele, S. & Rosenkilde, Mette, 2014, In: Current Medicinal Chemistry. 21, 31, p. 3594-614 21 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. 2013
    8. Published

      Structure-activity relationship studies of the aromatic positions in cyclopentapeptide CXCR4 antagonists

      Mungalpara, J., Zachariassen, Z. G., Thiele, S., Rosenkilde, Mette & Våbenø, J., 21 Dec 2013, In: Organic & Biomolecular Chemistry. 11, 47, p. 8202-8 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Structure-Activity Relationships and Identification of Optmized CC-Chemokine Receptor CCR1, 5, and 8 Metal-Ion Chelators

      Chalikiopoulos, A., Thiele, S., Malmgaard-Clausen, M., Rydberg, P., Isberg, V., Ulven, Trond, Frimurer, Thomas Michael, Rosenkilde, Mette & Gloriam, David E., 25 Nov 2013, In: Journal of Chemical Information and Modeling. 53, 11, p. 2863-73 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Multistep Continuous-Flow Synthesis in Medicinal Chemistry: Discovery and Preliminary Structure-Activity Relationships of CCR8 Ligands

      Petersen, T. P., Mirsharghi, S., Rummel, P. C., Thiele, S., Rosenkilde, Mette, Ritzén, A. & Ulven, Trond, 8 Jul 2013, In: Chemistry: A European Journal. 19, 28, p. 9343-50 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Extracellular Disulfide Bridges Serve Different Purposes in Two Homologous Chemokine Receptors, CCR1 and CCR5

      Rummel, P. C., Thiele, S., Gasbjerg, Lærke Smidt, Petersen, T. P., wbf943, wbf943, Ulven, T. & Rosenkilde, Mette, 13 Jun 2013, In: Current Molecular Pharmacology. 84, 3, p. 335-345 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Biased and Constitutive Signaling in the CC-Chemokine Receptor CCR5 by manipulating the Interface between Transmembrane Helix 6 and 7

      Steen, A., Thiele, S., Guo, D., Gasbjerg, Lærke Smidt, Frimurer, Thomas Michael & Rosenkilde, Mette, 3 May 2013, In: Journal of Biological Chemistry. 288, 18, p. 12511-12521 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Identification of common mechanisms by which human and mouse cytomegalovirus seven-transmembrane receptor homologues contribute to in vivo phenotypes in a mouse model

      Farrell, H. E., Abraham, A. M., Cardin, R. D., Mølleskov-Jensen, A., Rosenkilde, Mette & Davis-Poynter, N., Apr 2013, In: Journal of Virology. 87, 7, p. 4112-7 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Small molecule antagonism of oxysterol-induced Epstein-Barr virus induced gene 2 (EBI2) activation

      Benned-Jensen, T., Madsen, C. M., Arfelt, K. N., Smethurts, C., Blanchard, A., Jepras, R. & Rosenkilde, Mette, 2013, In: FEBS Open Bio. 3, p. 156-60 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. 2012
    16. Published

      Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice

      Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul, Viby, N., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hare, K. J. & Poulsen, Steen Seier, 10 Nov 2012, In: Regulatory Peptides. 179, 1-3, p. 91-100 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Molecular requirements for inhibition of the chemokine receptor CCR8--probe-dependent allosteric interactions

      Rummel, P. C., Arfelt, K. N., Baumann, L., Jenkins, T. J., Thiele, S., Lüttichau, H. R., Johnsen, A., Pease, J., Ghosh, S., Kolbeck, R. & Rosenkilde, Mette, Nov 2012, In: British Journal of Pharmacology. 167, 6, p. 1206-17 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183)

      Benned-Jensen, T., Norn, C., Laurent, S., Madsen, C. M., Larsen, H. M., Arfelt, K. N., Wolf, R. M., Frimurer, Thomas Michael, Sailer, A. W. & Rosenkilde, Mette, 12 Oct 2012, In: The Journal of Biological Chemistry. 287, 42, p. 35470-83 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Rational design of conformationally constrained cyclopentapeptide antagonists for C-x-C chemokine receptor 4 (CXCR4)

      Mungalpara, J., Thiele, S., Eriksen, Ø., Eksteen, J., Rosenkilde, Mette & Våbenø, J., 9 Oct 2012, In: Journal of Medicinal Chemistry. 55, 22, p. 10287-10291 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors

      Thiele, S., Malmgaard-Clausen, M., Engel-Andreasen, J., Steen, A., Rummel, P. C., Nielsen, M. C., Gloriam, David E., Frimurer, Thomas Michael, Ulven, Trond & Rosenkilde, Mette, 27 Sep 2012, In: Journal of Medicinal Chemistry. 55, 18, p. 8164-77 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      GPR119 as a fat sensor

      Hansen, Harald S., Rosenkilde, Mette, Holst, Jens Juul & Schwartz, Thue W., Jul 2012, In: Trends in Pharmacological Sciences. 33, 7, p. 374-81 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Reversed binding of a small molecule ligand in homologous chemokine receptors - differential role of extracellular loop 2

      Jensen, P. C., Thiele, S., Steen, A., Elder, A., Kolbeck, R., Ghosh, S., Frimurer, Thomas Michael & Rosenkilde, Mette, May 2012, In: British Journal of Pharmacology. 166, 1, p. 258-75 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Molecular Pharmacology of CXCR4 inhibition

      Steen, A. & Rosenkilde, Mette, 2012, Novel Developments in Stem Cell Mobilization : Focus on CXCR4. Fruehauf, S., Zeller, J. W. & Calandra, G. (eds.). Springer Science+Business Media, p. 23-35

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    24. Published

      Structural Diversity in Conserved Regions Like the DRY-Motif among Viral 7TM Receptors-A Consequence of Evolutionary Pressure?

      Mølleskov-Jensen, A., wbf943, wbf943, Davis-Poynter, N. & Rosenkilde, Mette, 2012, In: Advances in Virology. 2012, p. 231813

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. 2011
    26. Published

      Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain

      Ugleholdt, Randi Kjærsgaard, Pedersen, Jens, Bassi, Maria Rosaria, Füchtbauer, E., Jørgensen, S. M., Kissow, Hannelouise, Nytofte, N., Poulsen, Steen Seier, Rosenkilde, Mette, Seino, Y., Thams, P., Holst, Peter Johannes & Holst, Jens Juul, Dec 2011, In: The Journal of Biological Chemistry. 286, 52, p. 44632-44645 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Ligand Modulation of the Epstein-Barr Virus-induced Seven-transmembrane Receptor EBI2: IDENTIFICATION OF A POTENT AND EFFICACIOUS INVERSE AGONIST

      Benned-Jensen, T., Smethurst, C., Holst, Peter Johannes, Page, K. R., Sauls, H., Sivertsen, B. B., Schwartz, Thue W., Blanchard, A., Jepras, R. & Rosenkilde, Mette, 19 Aug 2011, In: Journal of Biological Chemistry. 286, p. 29292-29302 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Partial functional complementation between human and mouse cytomegalovirus chemokine receptor homologues

      Farrell, H. E., Abraham, A. M., Cardin, R. D., wbf943, wbf943, Rosenkilde, Mette, Spiess, Katja, Jensen, T. H., Kledal, T. N. & Davis-Poynter, N., Jun 2011, In: Journal of Virology. 85, 12, p. 6091-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans

      Hansen, K. B., Rosenkilde, Mette, Knop, Filip Krag, Wellner, N., Diep, T. A., Rehfeld, Jens Frederik, Andersen, U. B., Holst, Jens Juul & Hansen, Harald S., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 9, p. E1409-17

      Research output: Contribution to journal › Journal article › Research › peer-review

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