Mette Rosenkilde
Professor
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Selective Boosting of CCR7-Acting Chemokines; Short Peptides Boost Chemokines with Short Basic Tails, Longer Peptides Boost Chemokines with Long Basic Tails
Brandum, E. P., Jørgensen, Astrid Sissel, Calvo, M. B., Spiess, Katja, Peterson, F. C., Yang, Zhang, Volkman, B. F., Veldkamp, C. T., Rosenkilde, Mette, Goth, C. K. & Hjortø, Gertrud Malene, 2022, In: International Journal of Molecular Sciences. 23, 3, 20 p., 1397.Research output: Contribution to journal › Journal article › Research › peer-review
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Selective elimination of high constitutive activity or chemokine binding in the human herpesvirus 8 encoded seven transmembrane oncogene ORF74
Rosenkilde, Mette, Kledal, T. N., Holst, Peter Johannes & Schwartz, Thue W., 2000, In: Journal of Biological Chemistry. 275, 34, p. 26309-15 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Selective recognition of the membrane-bound CXC3 chemokine, fractal by the human cytomegalovirus-encoded broad-spectrum receptor US28
Kledal, T. N., Rosenkilde, Mette & Schwartz, Thue W., 1998, In: FEBS Letters. 441, p. 209-214Research output: Contribution to journal › Journal article › Research › peer-review
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Separate and Combined Glucometabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide 1 in Healthy Individuals
Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Jensen, M. H., Gabe, M. B. N., wbf943, wbf943, Veedfald, Simon, Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2019, In: Diabetes. 68, 3, p. 906-917Research output: Contribution to journal › Journal article › Research › peer-review
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Separate effects of glucagon like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) on bone remodelling
Skov-Jeppesen, Kirsa, Svane, M., Martinussen, C., Gabe, M., Gasbjerg, Lærke Smidt, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2018, In: Diabetologia. 61, S1, p. S245-S245 501.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Signaling via G proteins mediates tumorigenic effects of GPR87
Arfelt, K. N., Fares, S., wbf943, wbf943, Hjortø, Gertrud Malene, Gasbjerg, Lærke Smidt, Molleskov-Jensen, A., Benned-Jensen, T. & Rosenkilde, Mette, Jan 2017, In: Cellular Signalling. 30, p. 9-18Research output: Contribution to journal › Journal article › Research › peer-review
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Similar activation of signal transduction pathways by the herpesvirus-encoded chemokine receptors US28 and ORF74
McLean, K. A., Holst, Peter Johannes, Martini, L., Schwartz, Thue W. & Rosenkilde, Mette, 2004, In: Virology. 325, 2, p. 241-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Small molecule antagonism of oxysterol-induced Epstein-Barr virus induced gene 2 (EBI2) activation
Benned-Jensen, T., Madsen, C. M., Arfelt, K. N., Smethurts, C., Blanchard, A., Jepras, R. & Rosenkilde, Mette, 2013, In: FEBS Open Bio. 3, p. 156-60 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Species-specific action of (Pro3)GIP - an efficacious agonist on human GIP receptor, but partial agonist and competitive antagonist on rat and mouse GIP receptors
wbf943, wbf943, Gasbjerg, Lærke Smidt, Svendsen, B., Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Jan 2016, In: British Journal of Pharmacology. 173, 1, p. 27-38 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural Diversity in Conserved Regions Like the DRY-Motif among Viral 7TM Receptors-A Consequence of Evolutionary Pressure?
Mølleskov-Jensen, A., wbf943, wbf943, Davis-Poynter, N. & Rosenkilde, Mette, 2012, In: Advances in Virology. 2012, p. 231813Research output: Contribution to journal › Journal article › Research › peer-review
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Structural Features of an Extended C-Terminal Tail Modulate the Function of the Chemokine CCL21
Moussouras, N. A., Hjortø, Gertrud Malene, Peterson, F. C., Szpakowska, M., Chevigné, A., Rosenkilde, Mette, Volkman, B. F. & Dwinell, M. B., 7 Apr 2020, In: Biochemistry. 59, 13, p. 1338-1350 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1
Tsutsumi, N., Qu, Q., Mavri, M., Baggesen, M. S., Maeda, S., Waghray, D., Berg, Christian, Kobilka, B. K., Rosenkilde, Mette, Skiniotis, G. & Garcia, K. C., 2021, In: Immunity. 54, 7, p. 1405-+ 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist
Benned-Jensen, T. & Rosenkilde, Mette, 2008, In: Molecular Pharmacology. 74, 4, p. 1008-21 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure, function and physiological consequences of virally encoded chemokine seven transmembrane receptors
Rosenkilde, Mette, Smit, M. J. & Waldhoer, M., 2008, In: British Journal of Pharmacology. 153 Suppl 1, p. S154-66Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-Activity Relationships and Identification of Optmized CC-Chemokine Receptor CCR1, 5, and 8 Metal-Ion Chelators
Chalikiopoulos, A., Thiele, S., Malmgaard-Clausen, M., Rydberg, P., Isberg, V., Ulven, Trond, Frimurer, Thomas Michael, Rosenkilde, Mette & Gloriam, David E., 25 Nov 2013, In: Journal of Chemical Information and Modeling. 53, 11, p. 2863-73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-activity relationship studies of the aromatic positions in cyclopentapeptide CXCR4 antagonists
Mungalpara, J., Zachariassen, Z. G., Thiele, S., Rosenkilde, Mette & Våbenø, J., 21 Dec 2013, In: Organic & Biomolecular Chemistry. 11, 47, p. 8202-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-based discovery of novel US28 small molecule ligands with different modes of action
Lückmann, Michael, Amarandi, R., Papargyri, N., Jakobsen, M. H., Ulven, Elisabeth Rexen, Jensen, Lars Juhl, Pui, A., Schwartz, Thue W., Rosenkilde, Mette & Frimurer, Thomas Michael, 2017, In: Chemical Biology & Drug Design. 89, 3, p. 289–296Research output: Contribution to journal › Journal article › Research › peer-review
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Structure-function guided modeling of chemokine-GPCR specificity for the chemokine XCL1 and its receptor XCR1
Fox, J. C., Thomas, M. A., Dishman, A. F., Larsen, Olav, Nakayama, T., Yoshie, O., Rosenkilde, Mette & Volkman, B. F., 2019, In: Science Signaling. 12, 597, 15 p., eaat4128.Research output: Contribution to journal › Journal article › Research › peer-review
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Subcutaneous GIP and GLP-2 inhibit nightly bone resorption in postmenopausal women: A preliminary study
Skov-Jeppesen, Kirsa, Veedfald, Simon, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Bone. 152, 7 p., 116065.Research output: Contribution to journal › Journal article › Research › peer-review
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Sustained effect of glucagon on body weight and blood glucose: Assessed by continuous glucose monitoring in diabetic rats
Pedersen, C., Porsgaard, T., Thomsen, M., Rosenkilde, Mette & Roed, N. K., 2018, In: PLoS ONE. 13, 3, 17 p., .0194468.Research output: Contribution to journal › Journal article › Research › peer-review
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Sweet Taste Receptor Activation in the Gut Is of Limited Importance for Glucose-Stimulated GLP-1 and GIP Secretion
Saltiel, M. Y., Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Eliasen, R., Conde-Frieboes, K. W., Rosenkilde, Mette & Holst, Jens Juul, 2017, In: Nutrients. 9, 4, 15 p., 418.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis of a novel tripeptidomimetic scaffold and biological evaluation for CXC chemokine receptor 4 (CXCR4) antagonism
Baumann, M., Nome, L. M., Zachariassen, Z. G., Karlshoj, S., Fossen, T., Rosenkilde, Mette, Vabeno, J. & Haug, B. E., 2017, In: Tetrahedron. 73, 27-28, p. 3866-3877Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting CXCR4 in HIV Cell-Entry Inhibition
Steen, A., Schwartz, Thue W. & Rosenkilde, Mette, 2010, In: Mini reviews in medicinal chemistry. 9, 14, p. 1605-21 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting herpesvirus reliance of the chemokine system
Rosenkilde, Mette & Kledal, T. N., 2006, In: Current Drug Targets. 7, 1, p. 103-18 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting the latent cytomegalovirus reservoir with an antiviral fusion toxin protein
Krishna, B. A., Spiess, Katja, Poole, E. L., Lau, B., Voigt, S., Kledal, T. N., Rosenkilde, Mette & Sinclair, J. H., 2 Feb 2017, In: Nature Communications. 8, 14321.Research output: Contribution to journal › Journal article › Research › peer-review
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The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus
Jørgensen, Astrid Sissel, Brandum, E. P., Mikkelsen, J. M., Orfin, K. A., Boilesen, D. R., Egerod, Kristoffer Lihme, Moussouras, N. A., Vilhardt, Frederik, Kalinski, P., Basse, P., Chen, Yen-Hsi, Yang, Zhang, Dwinell, M. B., Volkman, B. F., Veldkamp, C. T., Holst, Peter Johannes, Lahl, K., Goth, C. K., Rosenkilde, Mette & Hjortø, Gertrud Malene, 2021, In: Cellular and Molecular Life Sciences. 78, p. 6963-6978 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The CCR5 receptor acts as an alloantigen in CCR5¿32 homozygous individuals: Identification of chemokine- and HIV-1 blocking human antibodies
Ditzel, H. J., Rosenkilde, Mette, Garred, P., Wang, M., Pedersen, C., Burton, D. R. & Schwartz, Thue W., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, no. 9, p. 5241-5245Research output: Contribution to journal › Journal article › Research › peer-review
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The CXC chemokine receptor encoded by herpesvirus saimiri, ECRF3, shows ligand-regulated signaling through Gi, Gq, and G12/13 proteins but constitutive signaling only through Gi and G12/13 proteins
Rosenkilde, Mette, McLean, K. A., Holst, Peter Johannes & Schwartz, Thue W., 2004, In: Journal of Biological Chemistry. 279, 31, p. 32524-33 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Dual GLP-1/GIP Receptor Agonist DA4-JC Shows Superior Protective Properties Compared to the GLP-1 Analogue Liraglutide in the APP/PS1 Mouse Model of Alzheimer's Disease
Maskery, M., Goulding, E. M., Gengler, S., Melchiorsen, J. U., Rosenkilde, Mette & Holscher, C., 2020, In: American Journal of Alzheimer's Disease and Other Dementias. 35, 11 p., 1533317520953041.Research output: Contribution to journal › Journal article › Research › peer-review
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The E92K melanocortin 1 receptor mutant induces cAMP production and arrestin recruitment but not ERK activity indicating biased constitutive signaling
Benned-Jensen, T., Mokrosinski, J. & Rosenkilde, Mette, 2011, In: P L o S One. 6, 9, p. e24644Research output: Contribution to journal › Journal article › Research › peer-review
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The European Research Network on Signal Transduction (ERNEST): Toward a Multidimensional Holistic Understanding of G Protein-Coupled Receptor Signaling
Sommer, M. E., Selent, J., Carlsson, J., De Graaf, C., Gloriam, David E., Keseru, G. M., Kosloff, M., Mordalski, S., Rizk, A., Rosenkilde, Mette, Sotelo, E., Tiemann, Johanna Katarina Sofie, Tobin, A., Vardjan, N., Waldhoer, M. & Kolb, P., 2020, In: ACS Pharmacology & Translational Science. 3, 2, p. 361-370 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Glucagon Receptor Antagonist LY2409021 has No Effect on Postprandial Glucose in Type 2 Diabetes
Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Forman, Julie Lyng, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 186, 2, p. 207-221 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor
Asmar, M., Asmar, A., Simonsen, L., Gasbjerg, Lærke Smidt, wbf943, wbf943, Rosenkilde, Mette, Hartmann, Bolette, Dela, Flemming, Holst, Jens Juul & Bülow, J., Sep 2017, In: Diabetes. 66, 9, p. 2363-2371 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Gβγ-subunit interacts directly with aquaporin-2 (AQP2) and regulates its membrane targeting
Olesen, Emma Tina Bisgaard, Poulsen, S. B., Rosenkilde, Mette, Sorensen, Charlotte Mehlin & Fenton, R. A., 2018.Research output: Contribution to conference › Conference abstract for conference › Research
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The Location of Missense Variants in the Human GIP Gene Is Indicative for Natural Selection
Lindquist, Peter, Gasbjerg, Lærke Smidt, Mokrosinski, J., Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, Mette, 2022, In: Frontiers in Endocrinology. 13, 14 p., 891586.Research output: Contribution to journal › Journal article › Research › peer-review
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The Novel Dual GLP-1/GIP Receptor Agonist DA-CH5 Is Superior to Single GLP-1 Receptor Agonists in the MPTP Model of Parkinson's Disease
Zhang, L., Zhang, L., Li, Y., Li, L., Melchiorsen, J. U., Rosenkilde, Mette & Holscher, C., 2020, In: Journal of Parkinson's Disease. 10, 2, p. 523-542Research output: Contribution to journal › Journal article › Research › peer-review
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The Secretome of Parental and Bone Metastatic Breast Cancer Elicits Distinct Effects in Human Osteoclast Activity after Activation of β2 Adrenergic Signaling
Conceição, F., Sousa, D. M., Tojal, S., Lourenço, C., Carvalho-Maia, C., Estevão-Pereira, H., Lobo, J., Couto, M., Rosenkilde, Mette, Jerónimo, C. & Lamghari, M., 2023, In: Biomolecules. 13, 4, 25 p., 622.Research output: Contribution to journal › Journal article › Research › peer-review
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The anorexic hormone Peptide YY3-36 is rapidly metabolized to inactive Peptide YY3-34 in vivo.
Toräng, S., Veedfald, Simon, Rosenkilde, Mette, Hartmann, Bolette & Holst, Jens Juul, 20 Jul 2015, In: Physiological Reports. 3, 7, p. 1-8 8 p., e12455.Research output: Contribution to journal › Journal article › Research › peer-review
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The antiresorptive effect of GIP, but not GLP-2, is preserved in patients with hypoparathyroidism - a randomized crossover study
Skov-Jeppesen, Kirsa, Hepp, N., Oeke, J., Hansen, M. S., Jafari Kermani, Abbas, Svane, M. S., Balenga, N., Olson, J. A., Frost, M., Kassem, Moustapha Saad El-Deen, Madsbad, Sten, Jensen, Jens-Erik Beck, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2021, In: Journal of Bone and Mineral Research. 36, 8, p. 1448-1458 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis
Waldhoer, M., Casarosa, P., Rosenkilde, Mette, Smit, M. J., Leurs, R., Whistler, J. L. & Schwartz, Thue W., 2003, In: Journal of Biological Chemistry. 278, 21, p. 19473-82 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endoytosis
Waldhoer, M., Casarosa, P., Rosenkilde, Mette, Smit, M. J., Leurs, R., Whistler, J. L. & Schwartz, Thue W., 2003, In: Journal of Biological Chemistry. Vol. 278 (21), p. 19473-82Research output: Contribution to journal › Journal article › Research › peer-review
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The chemokine system - a major regulator of angiogenesis in health and disease
Rosenkilde, Mette & Schwartz, Thue W., 2004, In: APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. Supplementum. Vol. 112, 7-8, p. 481-95Research output: Contribution to journal › Journal article › Research › peer-review
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The frequency of cytomegalovirus non-ELR UL146 genotypes in neonates with congenital CMV disease is comparable to strains in the background population
Berg, Christian, Rosenkilde, Mette, Benfield, Thomas, Nielsen, L., Sundelin, T. & Luttichau, H. R., 2021, In: BMC Infectious Diseases. 21, 1, 12 p., 386.Research output: Contribution to journal › Journal article › Research › peer-review
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The future of antiviral immunotoxins
Spiess, Katja, Jakobsen, M. H., Kledal, T. N. & Rosenkilde, Mette, Jun 2016, In: Journal of Leukocyte Biology. 99, 6, p. 911-925 15 p.Research output: Contribution to journal › Review › Research › peer-review
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The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine
Pedersen, Jens, B. Pedersen, N., Brix, S. W., Grunddal, Kaare Villum, Rosenkilde, Mette, Hartmann, Bolette, Ørskov, Cathrine, Poulsen, Steen Seier & Holst, Jens Juul, May 2015, In: Peptides. 67, p. 20-28 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The impact of short chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon
Christiansen, Charlotte Bayer, Gabe, M. B. N., Svendsen, B., Dragsted, Lars Ove, Rosenkilde, Mette & Holst, Jens Juul, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 315, 1, p. G53-G65 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery
Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347Research output: Contribution to journal › Journal article › Research › peer-review
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The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide
Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092Research output: Contribution to journal › Review › Research › peer-review
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The minor binding pocket: a major player in 7TM receptor activation
Rosenkilde, Mette, Benned-Jensen, T., Frimurer, T. M. & Schwartz, Thue W., 2010, In: Trends in Pharmacological Sciences. 31, 12, p. 567-574 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans
Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-Terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist
Berg, Christian, Wedemeyer, M. J., Melynis, M., Schlimgen, R. R., Hansen, L. H., Vabenø, J., Peterson, F. C., Volkman, B. F., Rosenkilde, Mette & Lüttichau, H. R., 2022, In: PLOS Pathogens. 18, 3, e1010355.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of endogenous GIP and GLP-1 in postprandial bone homeostasis
Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Bergmann, N. C., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Bone. 140, 7 p., 115553.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of incretins on insulin function and glucose homeostasis
Holst, Jens Juul, Gasbjerg, Lærke Smidt & Rosenkilde, Mette, 2021, In: Endocrinology. 162, 7, 10 p., bqab065.Research output: Contribution to journal › Review › Research › peer-review
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The role of transmembrane segment II in 7TM receptor activation
Benned-Jensen, T. & Rosenkilde, Mette, Jun 2009, In: Current Molecular Pharmacology. 2, 2, p. 140-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Therapeutic targeting of HCMV-encoded chemokine receptor US28: Progress and challenges
Berg, Christian & Rosenkilde, Mette, 2023, In: Frontiers in Immunology. 14, 8 p., 1135280.Research output: Contribution to journal › Review › Research › peer-review
- Published
Three-Dimensional Explant Platform for Studies on Choroid Plexus Epithelium
Petersen, N., Pedersen, Lola Julie Torz, Jensen, Kristian HR, Hjortø, Gertrud Malene, Spiess, Katja & Rosenkilde, Mette, 2020, In: Frontiers in Cellular Neuroscience. 14, 11 p., 108.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
Willard, F. S., Douros, J. D., Gabe, M., Showalter, A. D., Wainscott, D. B., Suter, T. M., Capozzi, M. E., van der Velden, W. J. C., Stutsman, C., Cardona, G. R., Urva, S., Emmerson, P. J., Holst, Jens Juul, D'Alessio, D. A., Coghlan, M. P., Rosenkilde, Mette, Campbell, J. E. & Sloop, K. W., 2020, In: JCI insight. 5, 17, 16 p., 140532.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transfer of liraglutide from blood to cerebrospinal fluid is minimal in patients with type 2 diabetes
Christensen, M., wbf943, wbf943, Hartmann, Bolette, Grevstad, U., Rosenkilde, Mette, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Nov 2015, In: International journal of obesity (2005). 39, 11, p. 1651-1654 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Transgenic rescue of adipocyte glucose-dependent insulinotropic polypeptide receptor expression restores high fat diet-induced body weight gain
Ugleholdt, Randi Kjærsgaard, Pedersen, Jens, Bassi, Maria Rosaria, Füchtbauer, E., Jørgensen, S. M., Kissow, Hannelouise, Nytofte, N., Poulsen, Steen Seier, Rosenkilde, Mette, Seino, Y., Thams, P., Holst, Peter Johannes & Holst, Jens Juul, Dec 2011, In: The Journal of Biological Chemistry. 286, 52, p. 44632-44645 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of insulin resistance and obesity by stimulating GLP-1 release
Hansen, Harald S., Diep, T. A., Holst, Jens Juul, Rosenkilde, Mette & Andersen, N. W., 29 Dec 2010, IPC No. A61K 31/23, Patent No. PCT/DK2010/050161, 24 Jun 2010Research output: Patent
- Published
Truncation of CXCL12 by CD26 reduces its CXC chemokine receptor 4- and atypical chemokine receptor 3-dependent activity on endothelial cells and lymphocytes
Janssens, R., Mortier, A., Boff, D., Ruytinx, P., Gouwy, M., Vantilt, B., Larsen, Olav, Daugvilaite, V., Rosenkilde, Mette, Parmentier, M., Noppen, S., Liekens, S., Van Damme, J., Struyf, S., Teixeira, M. M., Amaral, F. A. & Proost, P., 2017, In: Biochemical Pharmacology. 132, p. 92-101 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumorigenesis induced by the HHV8-encoded chemokine receptor requires ligand modulation of high constitutive activity
Holst, Peter Johannes, Rosenkilde, Mette, Manfra, D., Chen, S. C., Wiekowski, M. T., Holst, Birgitte, Cifire, F., Lipp, M., Schwartz, Thue W. & Lira, S. A., 2001, In: Journal of Clinical Investigation. 108, 12, p. 1789-96 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Using LanM Enzymes to Modify Glycagon-Like Peptides 1 and 2 in E.coli
Kjeldgaard Larsen, C., Lindquist, Peter, Rosenkilde, Mette, Ravn Madsen, A., Haselmann, K., Glendorf, T., Olesen, K., Bank Kodal, A. L. & Tørring, T., 3 May 2024, (E-pub ahead of print) In: ChemBioChem. p. e202400201Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration
González-Motos, V., Jürgens, C., Ritter, B., Kropp, K. A., Durán, V., Larsen, Olav, Binz, A., Ouwendijk, W. J. D., Lenac Rovis, T., Jonjic, S., Verjans, G. M. G. M., Sodeik, B., Krey, T., Bauerfeind, R., Schulz, T. F., Kaufer, B. B., Kalinke, U., Proudfoot, A. E. I., Rosenkilde, Mette & Viejo-Borbolla, A., May 2017, In: PLOS Pathogens. 13, 5, 28 p., e1006346.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vasopressin receptors V1a and V2 are not osmosensors
Pedersen, K. L., Assentoft, M., Fenton, R. A., Rosenkilde, Mette & MacAulay, Nanna, Aug 2015, In: Physiological Reports. 3, 8, 11 p., e12519.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Viral G Protein-Coupled Receptors Encoded by β- and γ-Herpesviruses
Rosenkilde, Mette, Tsutsumi, N., Knerr, J. M., Kildedal, Dagmar Fæster & Garcia, K. C., 2022, In: Annual Review of Virology. 9, 1, p. 329-351Research output: Contribution to journal › Review › Research › peer-review
- Published
Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy
Miles, T. F., Spiess, Katja, Jude, K. M., Tsutsumi, N., Burg, J. S., Ingram, J. R., Waghray, D., Hjortø, Gertrud Malene, Larsen, Olav, Ploegh, H. L., Rosenkilde, Mette & Garcia, K. C., 2018, In: eLife. 7, 23 p., e35850 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Virally encoded 7TM receptors
Rosenkilde, Mette, Waldhoer, M., Lüttichau, H. R. & Schwartz, Thue W., 2001, In: Oncogene. 20, 13, p. 1582-93 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Virally encoded chemokines and chemokine receptors in the role of viral infections
Holst, Peter Johannes, Lüttichau, H. R., Schwartz, Thue W. & Rosenkilde, Mette, 2003, In: Contributions to Microbiology. 10, p. 232-52 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Virus-encoded chemokine receptors - putative novel innovative drug targets
Rosenkilde, Mette, 2005, In: Neuropharmacology. Vol. 48, no. 1, p. 1-13Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Virus-encoded chemokine receptors--putative novel antiviral drug targets
Rosenkilde, Mette, 2005, In: Neuropharmacology. 48, 1, p. 1-13 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
“Glyco-sulfo barcodes” regulate chemokine receptor function
Verhallen, L., Lackman, Jarkko Juhani, Wendt, R., Gustavsson, Martin, Yang, Zhang, Narimatsu, Yoshiki, Sørensen, Daniel Madriz, Lafferty, K. M., Gouwy, M., Marques, P. E., Hjortø, Gertrud Malene, Rosenkilde, Mette, Proost, P. & Goth, C. K., 2023, In: Cellular and Molecular Life Sciences. 80, 2, 18 p., 55.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacokinetics of oral and intravenous melatonin in healthy volunteers
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Differential CCR7 Targeting in Dendritic Cells by Three Naturally Occurring CC-Chemokines
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Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119
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