Christina Christoffersen

Christina Christoffersen

Associate Professor


Publication year:
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1 - 50 out of 99Page size: 50
  1. 2002
  2. Published

    Chamber-dependent expression of brain natriuretic peptide and its mRNA in normal and diabetic pig heart

    Christoffersen, Christina, Goetze, Jens P. , Bartels, Emil Daniel, Larsen, T. M., Ribel, U., Rehfeld, Jens Frederik, Rolin, B. & Nielsen, L. B., Jul 2002, In: Hypertension. 40, 1, p. 54-60 7 p.

    Research output: Contribution to journal › Journal article › Research

  3. 2003
  4. Published

    Increased cardiac BNP expression associated with myocardial ischemia

    Goetze, Jens P. , Christoffersen, Christina, Perko, M., Arendrup, H., Rehfeld, Jens Frederik, Kastrup, J. & Nielsen, L. B., Jun 2003, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 17, 9, p. 1105-7 3 p.

    Research output: Contribution to journal › Journal article › Research

  5. Published

    Cardiac lipid accumulation associated with diastolic dysfunction in obese mice

    Christoffersen, Christina, Bollano, E., Lindegaard, M. L. S., Bartels, Emil Daniel, Goetze, Jens P. , Andersen, C. B. & Nielsen, L. B., Aug 2003, In: Molecular Endocrinology. 144, 8, p. 3483-90 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. 2005
  7. Published

    Endothelial and lipoprotein lipases in human and mouse placenta

    Lindegaard, M. L. S., Olivecrona, G., Christoffersen, Christina, Kratky, D., Hannibal, Jens, Petersen, B. L., Zechner, R., Damm, Peter & Nielsen, L. B., Nov 2005, In: Journal of Lipid Research. 46, 11, p. 2339-46 8 p.

    Research output: Contribution to journal › Journal article › Research

  8. Published

    Endothelial and lipoprotein lipases in human and mouse placenta

    Lindegaard, M. L. S., Olivecrona, G., Christoffersen, Christina, Kratky, D., Hannibal, Jens, Petersen, B. L., Zechner, R., Damm, Peter & Nielsen, L. B., 1 Nov 2005, In: Journal of Lipid Research. 46, 11, p. 2339-46 8 p.

    Research output: Contribution to journal › Journal article › Research

  9. 2006
  10. Published

    Apolipoprotein M: progress in understanding its regulation and metabolic functions

    Christoffersen, Christina, Dahlbäck, B. & Nielsen, L. B., 2006, In: Scandinavian Journal of Clinical & Laboratory Investigation. 66, 7, p. 631-7 7 p.

    Research output: Contribution to journal › Journal article › Research

  11. Published

    Heart specific up-regulation of genes for B-type and C-type natriuretic peptide receptors in diabetic mice

    Christoffersen, Christina, Bartels, Emil Daniel & Nielsen, L. B., Feb 2006, In: European Journal of Clinical Investigation. 36, 2, p. 69-75 7 p.

    Research output: Contribution to journal › Journal article › Research

  12. Published

    Isolation and characterization of human apolipoprotein M-containing lipoproteins

    Christoffersen, Christina, Nielsen, L. B., Axler, O., Andersson, A., Johnsen, A. H. & Dahlbäck, B., Aug 2006, In: Journal of Lipid Research. 47, 8, p. 1833-43 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. 2007
  14. Published

    Diabetes and the endocrine heart

    Christoffersen, Christina, Hunter, I., Jensen, Asger Lundorff & Goetze, Jens P. , Oct 2007, In: European Heart Journal. 28, 20, p. 2427-9 3 p.

    Research output: Contribution to journal › Editorial › Research

  15. 2008
  16. Published

    Apolipoprotein M: Structure and Function

    Dahlback, B., Ahnstrom, J., Christoffersen, Christina & Nielsen, L. B., 2008, In: Future Lipidology. 3, p. 495-503

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The signal peptide anchors apolipoprotein M in plasma lipoproteins and prevents rapid clearance of apolipoprotein M from plasma

    Christoffersen, Christina, Ahnström, J., Axler, O., Christensen, E. I., Dahlbäck, B. & Nielsen, L. B., 2008, In: Journal of Biological Chemistry. 283, 27, p. 18765-72 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The signal peptide anchors apolipoprotein m in plasma lipoproteins and prevents rapid clearance of apolipoprotein m from plasma

    Christoffersen, Christina, Ahnstrom, J., Axler, O., Christensen, E. I., Dahlback, B. & Nielsen, L. B., 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 6, p. E62-E63

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice

    Christoffersen, Christina, Jauhiainen, M., Moser, M., Porse, Bo Torben, Ehnholm, C., Boesl, M., Dahlbäck, B. & Nielsen, L. B., 25 Jan 2008, In: The Journal of Biological Chemistry. 283, 4, p. 1839-47 9 p.

    Research output: Contribution to journal › Journal article › Research

  20. 2009
  21. Published

    ApoM: gene regulation and effects on HDL metabolism

    Nielsen, L. B., Christoffersen, Christina, Ahnström, J. & Dahlbäck, B., 2009, In: Trends in Endocrinology and Metabolism. 20, 2, p. 66-71 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Heparininduceret trombocytopeni

    Christoffersen, Christina, Lethagen, S. & Goetze, Jens P. , 16 Feb 2009, In: Ugeskrift for Laeger. 171, 8, p. 612-5 4 p.

    Research output: Contribution to journal › Journal article › Research

  23. 2010
  24. Published

    Opposing effects of apolipoprotein m on catabolism of apolipoprotein B-containing lipoproteins and atherosclerosis

    Christoffersen, Christina, Pedersen, T. X., Gordts, P. L. S. M., Roebroek, A. J. M., Dahlbäck, B. & Nielsen, L. B., 2010, In: Circulation Research. 106, 10, p. 1624-34 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. 2011
  26. Published

    Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M

    Christoffersen, Christina, Obinata, H., Kumaraswamy, S. B., Galvani, S., Ahnström, J., Sevvana, M., Egerer-Sieber, C., Muller, Y. A., Hla, T., Nielsen, L. B. & Dahlbäck, B., 2011, In: Proceedings of the National Academy of Sciences USA (PNAS). 108, 23, p. 9613-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2012
  28. Published

    (18)F-FDG PET imaging of murine atherosclerosis: association with gene expression of key molecular markers

    Hag, Anne Mette Fisker, Pedersen, S. F., Christoffersen, Christina, Binderup, Tina, Wessel, Mette Munk, Jørgensen, Jesper Tranekjær, Skovgaard, D., Ripa, Rasmus Sejersten & Kjær, Andreas, 2012, In: P L o S One. 7, 11, p. e50908

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Apolipoprotein M - a new biomarker in sepsis

    Christoffersen, Christina & Nielsen, L. B., 2012, In: Critical Care (Online Edition). 16, 3, p. 126

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL

    Elsøe, S., Ahnström, J., Christoffersen, Christina, Hoofnagle, A. N., Plomgaard, Peter Stendahl, Heinecke, J. W., Binder, C. J., Björkbacka, H., Dahlbäck, B. & Nielsen, L. B., 2012, In: Atherosclerosis. 221, 1, p. 91-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice

    Gordts, P. L. S. M., Bartelt, A., Nilsson, S. K., Annaert, W., Christoffersen, Christina, Nielsen, L. B., Heeren, J. & Roebroek, A. J. M., 2012, In: P L o S One. 7, 6, p. e38330

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    The plasma concentration of HDL-associated apolipoprotein M is influenced by LDL-receptor-mediated clearance of apoB-containing particles

    Christoffersen, Christina, Benn, Marianne, Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dahlback, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. 2013
  34. Published

    Cardiac natriuretic peptide gene expression and plasma concentrations during the first 72 hours of life in piglets

    Smith, J., Christoffersen, Christina, Nørgaard, L. M., Olsen, Lisbeth Høier, Vejlstrup, N. G., Andersen, C. B. & Gøtze, J. P., 2013, In: Endocrinology. 154, 5, p. 1864-1872 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant

    Al-Mashhadi, R. H., Sørensen, C. B., Kragh, P. M., Christoffersen, C., Mortensen, M. B., Tolbod, L. P., Thim, T., Du, Y., Li, J., Liu, Y., Moldt, B., Schmidt, M., Vajta, G., Larsen, T., Purup, S., Bolund, L., Nielsen, L. B., Callesen, H., Falk, E., Mikkelsen, J. G. & 1 others, Bentzon, J. F., 2013, In: Science Translational Medicine. 5, 166, 11 p., 166ra1.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The apolipoprotein m-sphingosine-1-phosphate axis: biological relevance in lipoprotein metabolism, lipid disorders and atherosclerosis

    Arkensteijn, B. W. C., Berbée, J. F. P., Rensen, P. C. N., Nielsen, L. B. & Christoffersen, Christina, 25 Feb 2013, In: International Journal of Molecular Sciences (Online). 14, 3, p. 4419-31 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Osteopontin deficiency dampens the pro-atherogenic effect of uraemia

    Pedersen, T. X., Madsen, M., Nielsen, N. M. J., Christoffersen, Christina, Vikeså, J., Bro, S., Hultgårdh-Nilsson, A. & Nielsen, L. B., 1 Jun 2013, In: Cardiovascular Research. 98, 3, p. 352-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Apolipoprotein M promotes mobilization of cellular cholesterol in vivo

    Elsøe, S., Christoffersen, Christina, Luchoomun, J., Turner, S. & Nielsen, L. B., Jul 2013, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1831, 7, p. 1287-92 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Apolipoprotein M: bridging HDL and endothelial function

    Christoffersen, Christina & Nielsen, L. B., Aug 2013, In: Current Opinion in Lipidology. 24, 4, p. 295-300 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. 2014
  41. Published

    Apolipoprotein M: Impact on lipoprotein metabolism and vascular function

    Christoffersen, Christina, 2014, Frederiksberg: Det Sundhedsvidenskabelige Fakultet, Københavns Universitet. 118 p.

    Research output: Book/Report › Doctoral thesis › Research

  42. Published

    Effect of atrial natriuretic peptide on lipolysis in the mouse heart

    Bartels, Emil Daniel, Bisgaard, Line, Christoffersen, Christina & Nielsen, L. B., 2014, In: Cardiovascular Endocrinology. 3, 3, p. 92-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Induction of atherosclerosis in mice and hamsters without germline genetic engineering

    Bjørklund, M. M., Hollensen, A. K., Hagensen, M. K., Dagnæs-Hansen, F., Christoffersen, Christina, Mikkelsen, J. G. & Bentzon, J. F., 23 May 2014, In: Circulation Research. 114, 11, p. 1684-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. 2015
  45. Published

    Altered Metabolism of LDL in the Arterial Wall Precedes Atherosclerosis Regression

    Bartels, Emil Daniel, Christoffersen, Christina, Lindholm, M. W. & Nielsen, L. B., 2015, In: Circulation Research. 117, p. 933-942 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Diabetes with poor glycaemic control does not promote atherosclerosis in genetically modified hypercholesterolaemic minipigs

    Al-Mashhadi, R. H., Bjørklund, M. M., Mortensen, M. B., Christoffersen, Christina, Larsen, T., Falk, E. & Bentzon, J. F., 2015, In: Diabetologia. 58, 8, p. 1926-36 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Apolipoprotein M in lipid metabolism and cardiometabolic diseases

    Borup, A., Christensen, P. M., Nielsen, L. B. & Christoffersen, Christina, Feb 2015, In: Current Opinion in Lipidology. 26, 1, p. 48-55 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    Protein unfolding allows use of commercial antibodies in an apolipoprotein M sandwich ELISA

    Bosteen, M. H., Dahlbäck, B., Nielsen, L. B. & Christoffersen, Christina, 1 Mar 2015, In: Journal of Lipid Research. 56, 3, p. 754-759 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Diurnal gene expression of lipolytic natriuretic peptide receptors in white adipose tissue

    Smith, J., Fahrenkrug, J., Jørgensen, H. L., Christoffersen, Christina & Goetze, J. P., Dec 2015, In: Endocrine Connections. 4, 4, p. 206-214 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. 2016
  51. Published

    Sphingosine-1-Phosphate reduces ischemia/reperfusion injury by phosphorylating the gap junction protein Connexin43

    Morel, S., Christoffersen, Christina, Axelsen, L. N., Montecucco, F., Rochemont, V., Frias, M. A., Mach, F., James, R. W., Naus, C. C., Chanson, M., Lampe, P. D., Nielsen, Morten Schak, Nielsen, L. B. & Kwak, B. R., 13 Jan 2016, In: Cardiovascular Research. 109, p. 385-396 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Impaired endothelial barrier function in apolipoprotein M-deficient mice is dependent on sphingosine-1-phosphate receptor 1

    Christensen, P. M., Liu, C. H., Swendeman, S. L., Obinata, H., Qvortrup, Klaus, Nielsen, L. B., Hla, T., Di Lorenzo, A. & Christoffersen, Christina, Jun 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 6, p. 2351-2359 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Familial hypercholesterolaemia: cholesterol efflux and coronary disease

    Versmissen, J., Vongpromek, R., Yahya, R., van der Net, J. B., van Vark-van der Zee, L., Blommesteijn-Touw, J., Wattimena, D., Rietveld, T., Pullinger, C. R., Christoffersen, Christina, Dahlbäck, B., Kane, J. P., Mulder, M. & Sijbrands, E. J. G., Jul 2016, In: European Journal of Clinical Investigation. 46, 7, p. 643-50 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents

    Khetarpal, S. A., Schjoldager, K. T., Christoffersen, C., Raghavan, A., Edmondson, A. C., Reutter, H. M., Ahmed, B., Ouazzani, R., Peloso, G. M., Vitali, C., Zhao, W., Somasundara, A. V. H., Millar, J. S., Park, Y., Fernando, G., Livanov, V., Choi, S., Noé, E., Patel, P., Ho, S. P. & 12 others, Kirchgessner, T. G., Wandall, Hans H., Hansen, Lars, Bennett, Eric Paul, Vakhrushev, Sergey, Saleheen, D., Kathiresan, S., Brown, C. D., Abou Jamra, R., LeGuern, E., Clausen, Henrik & Rader, D. J., 9 Aug 2016, In: Cell Metabolism. 24, 2, p. 234-245 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of Atherosclerosis

    Pedersen, A. A., Pedersen, T. X., Junker, N., Christoffersen, Christina, Bartels, Emil Daniel, Madsen, M., Nielsen, Carsten Haagen & Nielsen, L. B., Sep 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 9, p. 1782-1790 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver

    Ding, B., Liu, C. H., Sun, Y., Chen, Y., Swendeman, S. L., Jung, B., Chavez, D., Cao, Z., Christoffersen, Christina, Nielsen, L. B., Schwab, S. R., Rafii, S. & Hla, T., 22 Dec 2016, In: JCI insight. 1, 21, 16 p., e87058.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. 2017
  58. Published

    Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs

    Shim, J., Poulsen, C. B., Hagensen, M. K., Larsen, T., Heegaard, P. M. H., Christoffersen, Christina, Bolund, L., Schmidt, M., Liu, Y., Li, J., Li, R., Callesen, H., Bentzon, J. F. & Sørensen, C. B., 2017, In: JACC: Basic to Translational Science. 2, 5, p. 591-600 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression

    Feuerborn, R., Becker, S., Potì, F., Nagel, P., Brodde, M., Schmidt, H., Christoffersen, Christina, Ceglarek, U., Burkhardt, R. & Nofer, J., Feb 2017, In: Atherosclerosis. 257, p. 29-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation

    Hajny, Stefan & Christoffersen, Christina, 27 Jul 2017, In: International Journal of Molecular Sciences. 18, 8, 19 p., 1636.

    Research output: Contribution to journal › Review › Research › peer-review

  61. Published

    Effects of apolipoprotein M in uremic atherosclerosis

    Bosteen, M. H., Madsen Svarrer, E. M., Bisgaard, Line, Martinussen, Torben, Madsen, M., Nielsen, L. B., Christoffersen, Christina & Pedersen, T. X., Oct 2017, In: Atherosclerosis. 265, p. 93-101 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes

    Christensen, P. M., Bosteen, M. H., Hajny, Stefan, Nielsen, L. B. & Christoffersen, Christina, 8 Nov 2017, In: Scientific Reports. 7, 10 p., 14983.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    ApoB and apoM - New aspects of lipoprotein biology in uremia-induced atherosclerosis

    Christoffersen, Christina, Bartels, Emil Daniel, Pedersen, A. A., Nielsen, L. B. & Pedersen, T. X., Dec 2017, In: European Journal of Pharmacology. 816, p. 154-160 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. 2018
  65. Published

    Apolipoprotein M in patients with chronic kidney disease

    Sørensen, I. M., Bertelsen, M., Freese, E., Lindhard, K., Ullum, H., Feldt-Rasmussen, Bo, Nielsen, L. B., Christoffersen, Christina & Bro, S., 2018, In: Atherosclerosis. 275, p. 304-311

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Functional brown adipose tissue and sympathetic activity after cold exposure in humans with type 1 narcolepsy

    Enevoldsen, L. H., Tindborg, M., Hovmand, N. L., Christoffersen, Christina, Ellingsgaard, H., Suetta, Charlotte, Stallknecht, Bente Merete, Jennum, Poul, Kjær, Andreas & Gammeltoft, S., 2018, In: Sleep. 41, 8, p. 1-9 zsy092.

    Research output: Contribution to journal › Journal article › Research › peer-review

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