Christina Christoffersen
Associate Professor
Physiology of circulation, kidney and lung
Blegdamsvej 3
2200 København N.
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Apolipoprotein M-A Marker or an Active Player in Type II Diabetes?
Christoffersen, Christina, 2021, In: Frontiers in Endocrinology. 12, 10 p., 665393.Research output: Contribution to journal › Review › Research › peer-review
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Isolation and characterization of human apolipoprotein M-containing lipoproteins
Christoffersen, Christina, Nielsen, L. B., Axler, O., Andersson, A., Johnsen, A. H. & Dahlbäck, B., Aug 2006, In: Journal of Lipid Research. 47, 8, p. 1833-43 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The plasma concentration of HDL-associated apolipoprotein M is influenced by LDL-receptor-mediated clearance of apoB-containing particles
Christoffersen, Christina, Benn, Marianne, Christensen, P. M., Gordts, P. L. S. M., Roebroek, A. J. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dahlback, B. & Nielsen, L. B., 2012, In: Journal of Lipid Research.Research output: Contribution to journal › Journal article › Research › peer-review
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The signal peptide anchors apolipoprotein M in plasma lipoproteins and prevents rapid clearance of apolipoprotein M from plasma
Christoffersen, Christina, Ahnström, J., Axler, O., Christensen, E. I., Dahlbäck, B. & Nielsen, L. B., 2008, In: Journal of Biological Chemistry. 283, 27, p. 18765-72 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice
Christoffersen, Christina, Jauhiainen, M., Moser, M., Porse, Bo Torben, Ehnholm, C., Boesl, M., Dahlbäck, B. & Nielsen, L. B., 25 Jan 2008, In: The Journal of Biological Chemistry. 283, 4, p. 1839-47 9 p.Research output: Contribution to journal › Journal article › Research
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Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M
Christoffersen, Christina, Obinata, H., Kumaraswamy, S. B., Galvani, S., Ahnström, J., Sevvana, M., Egerer-Sieber, C., Muller, Y. A., Hla, T., Nielsen, L. B. & Dahlbäck, B., 2011, In: Proceedings of the National Academy of Sciences USA (PNAS). 108, 23, p. 9613-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Opposing effects of apolipoprotein m on catabolism of apolipoprotein B-containing lipoproteins and atherosclerosis
Christoffersen, Christina, Pedersen, T. X., Gordts, P. L. S. M., Roebroek, A. J. M., Dahlbäck, B. & Nielsen, L. B., 2010, In: Circulation Research. 106, 10, p. 1624-34 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein M: progress in understanding its regulation and metabolic functions
Christoffersen, Christina, Dahlbäck, B. & Nielsen, L. B., 2006, In: Scandinavian Journal of Clinical & Laboratory Investigation. 66, 7, p. 631-7 7 p.Research output: Contribution to journal › Journal article › Research
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Apolipoprotein M: bridging HDL and endothelial function
Christoffersen, Christina & Nielsen, L. B., Aug 2013, In: Current Opinion in Lipidology. 24, 4, p. 295-300 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heart specific up-regulation of genes for B-type and C-type natriuretic peptide receptors in diabetic mice
Christoffersen, Christina, Bartels, Emil Daniel & Nielsen, L. B., Feb 2006, In: European Journal of Clinical Investigation. 36, 2, p. 69-75 7 p.Research output: Contribution to journal › Journal article › Research
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Cardiac lipid accumulation associated with diastolic dysfunction in obese mice
Christoffersen, Christina, Bollano, E., Lindegaard, M. L. S., Bartels, Emil Daniel, Goetze, Jens P. , Andersen, C. B. & Nielsen, L. B., Aug 2003, In: Molecular Endocrinology. 144, 8, p. 3483-90 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity
Christoffersen, Christina, Federspiel, C. K., Borup, A., Christensen, P. M., Madsen, A. N., Heine, M., Nielsen, C. H., Kjaer, A., Holst, Birgitte, Heeren, J. & Nielsen, L. B., 2 Jan 2018, In: Cell Reports. 22, 1, p. 175-188Research output: Contribution to journal › Journal article › Research › peer-review
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Chamber-dependent expression of brain natriuretic peptide and its mRNA in normal and diabetic pig heart
Christoffersen, Christina, Goetze, Jens P. , Bartels, Emil Daniel, Larsen, T. M., Ribel, U., Rehfeld, Jens Frederik, Rolin, B. & Nielsen, L. B., Jul 2002, In: Hypertension. 40, 1, p. 54-60 7 p.Research output: Contribution to journal › Journal article › Research
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Heparininduceret trombocytopeni
Christoffersen, Christina, Lethagen, S. & Goetze, Jens P. , 16 Feb 2009, In: Ugeskrift for Laeger. 171, 8, p. 612-5 4 p.Research output: Contribution to journal › Journal article › Research
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Apolipoprotein M: Impact on lipoprotein metabolism and vascular function
Christoffersen, Christina, 2014, Frederiksberg: Det Sundhedsvidenskabelige Fakultet, Københavns Universitet. 118 p.Research output: Book/Report › Doctoral thesis › Research
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Apolipoprotein M: Structure and Function
Dahlback, B., Ahnstrom, J., Christoffersen, Christina & Nielsen, L. B., 2008, In: Future Lipidology. 3, p. 495-503Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating cord blood HDL-S1P complex preserves the integrity of the feto-placental vasculature
Del Gaudio, I., Sreckovic, I., Zardoya-Laguardia, P., Bernhart, E., Christoffersen, Christina, Frank, S., Marsche, G., Illanes, S. E. & Wadsack, C., 2020, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1865, 4, 11 p., 158632.Research output: Contribution to journal › Journal article › Research › peer-review
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Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair
Ding, B. S., Yang, D., Swendeman, S. L., Christoffersen, Christina, Nielsen, L. B., Friedman, S. L., Powell, C. A., Hla, T. & Cao, Z., 2020, In: Developmental Cell. 53, 6, p. 677-690Research output: Contribution to journal › Journal article › Research › peer-review
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HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver
Ding, B., Liu, C. H., Sun, Y., Chen, Y., Swendeman, S. L., Jung, B., Chavez, D., Cao, Z., Christoffersen, Christina, Nielsen, L. B., Schwab, S. R., Rafii, S. & Hla, T., 22 Dec 2016, In: JCI insight. 1, 21, 16 p., e87058.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of Glomerular and Plasma Apolipoprotein M as Novel Biomarkers in Glomerular Disease
Drexler, Y., Molina, J., Elfassy, T., Ma, R., Christoffersen, Christina, Kurano, M., Yatomi, Y., Mariani, L. H., Contreras, G., Merscher, S. & Fornoni, A., 2023, In: Kidney International Reports. 8, 4, p. 884-897Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL
Elsøe, S., Ahnström, J., Christoffersen, Christina, Hoofnagle, A. N., Plomgaard, Peter Stendahl, Heinecke, J. W., Binder, C. J., Björkbacka, H., Dahlbäck, B. & Nielsen, L. B., 2012, In: Atherosclerosis. 221, 1, p. 91-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein M promotes mobilization of cellular cholesterol in vivo
Elsøe, S., Christoffersen, Christina, Luchoomun, J., Turner, S. & Nielsen, L. B., Jul 2013, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1831, 7, p. 1287-92 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional brown adipose tissue and sympathetic activity after cold exposure in humans with type 1 narcolepsy
Enevoldsen, L. H., Tindborg, M., Hovmand, N. L., Christoffersen, Christina, Ellingsgaard, H., Suetta, Charlotte, Stallknecht, Bente Merete, Jennum, Poul, Kjær, Andreas & Gammeltoft, S., 2018, In: Sleep. 41, 8, p. 1-9 zsy092.Research output: Contribution to journal › Journal article › Research › peer-review
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High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression
Feuerborn, R., Becker, S., Potì, F., Nagel, P., Brodde, M., Schmidt, H., Christoffersen, Christina, Ceglarek, U., Burkhardt, R. & Nofer, J., Feb 2017, In: Atherosclerosis. 257, p. 29-37 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice
Galsgaard, Katrine Douglas, Elmelund, E., Johansen, C. D., Billeschou, Anna, Kizilkaya, Hüsün Sheyma, Ceutz, F., Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Winther-Sørensen, Marie, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Rosenkilde, Mette, Ørskov, Cathrine, Christoffersen, Christina, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Molecular Metabolism. 66, 14 p., 101639.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 18392597
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A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation
Research output: Contribution to journal › Review › Research › peer-review
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Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes
Research output: Contribution to journal › Journal article › Research › peer-review
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240
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The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity
Research output: Contribution to journal › Journal article › Research › peer-review
Published