Christina Christoffersen

Christina Christoffersen

Associate Professor


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  1. Published

    Familial hypercholesterolaemia: cholesterol efflux and coronary disease

    Versmissen, J., Vongpromek, R., Yahya, R., van der Net, J. B., van Vark-van der Zee, L., Blommesteijn-Touw, J., Wattimena, D., Rietveld, T., Pullinger, C. R., Christoffersen, Christina, Dahlbäck, B., Kane, J. P., Mulder, M. & Sijbrands, E. J. G., Jul 2016, In: European Journal of Clinical Investigation. 46, 7, p. 643-50 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant

    Al-Mashhadi, R. H., Sørensen, C. B., Kragh, P. M., Christoffersen, C., Mortensen, M. B., Tolbod, L. P., Thim, T., Du, Y., Li, J., Liu, Y., Moldt, B., Schmidt, M., Vajta, G., Larsen, T., Purup, S., Bolund, L., Nielsen, L. B., Callesen, H., Falk, E., Mikkelsen, J. G. & 1 others, Bentzon, J. F., 2013, In: Science Translational Medicine. 5, 166, 11 p., 166ra1.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Functional brown adipose tissue and sympathetic activity after cold exposure in humans with type 1 narcolepsy

    Enevoldsen, L. H., Tindborg, M., Hovmand, N. L., Christoffersen, Christina, Ellingsgaard, H., Suetta, Charlotte, Stallknecht, Bente Merete, Jennum, Poul, Kjær, Andreas & Gammeltoft, S., 2018, In: Sleep. 41, 8, p. 1-9 zsy092.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding

    Tian, E., Wang, S., Zhang, L., Zhang, Y., Malicdan, M. C., Mao, Y., Christoffersen, Christina, Tabak, L. A., Schjoldager, Katrine Ter-Borch Gram & Ten Hagen, K. G., 10 Dec 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 50, p. 25196-25202

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Gestational Hypertension and High-Density Lipoprotein Function: An Explorative Study in Overweight/Obese Women of the DALI Cohort

    Stadler, J. T., van Poppel, M. N. M., Christoffersen, Christina, Hill, D., Wadsack, C., Simmons, D., Desoye, G., Marsche, G. & DALI Core Investigator Grp, 2023, In: Antioxidants. 12, 1, 13 p., 68.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Glucagon receptor antagonism impairs and glucagon receptor agonism enhances triglycerides metabolism in mice

    Galsgaard, Katrine Douglas, Elmelund, E., Johansen, C. D., Billeschou, Anna, Kizilkaya, Hüsün Sheyma, Ceutz, F., Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Winther-Sørensen, Marie, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Rosenkilde, Mette, Ørskov, Cathrine, Christoffersen, Christina, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Molecular Metabolism. 66, 14 p., 101639.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver

    Ding, B., Liu, C. H., Sun, Y., Chen, Y., Swendeman, S. L., Jung, B., Chavez, D., Cao, Z., Christoffersen, Christina, Nielsen, L. B., Schwab, S. R., Rafii, S. & Hla, T., 22 Dec 2016, In: JCI insight. 1, 21, 16 p., e87058.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Heart specific up-regulation of genes for B-type and C-type natriuretic peptide receptors in diabetic mice

    Christoffersen, Christina, Bartels, Emil Daniel & Nielsen, L. B., Feb 2006, In: European Journal of Clinical Investigation. 36, 2, p. 69-75 7 p.

    Research output: Contribution to journal › Journal article › Research

  9. Published

    Heparininduceret trombocytopeni

    Christoffersen, Christina, Lethagen, S. & Goetze, Jens P. , 16 Feb 2009, In: Ugeskrift for Laeger. 171, 8, p. 612-5 4 p.

    Research output: Contribution to journal › Journal article › Research

  10. Published

    High density lipoprotein (HDL)-associated sphingosine 1-phosphate (S1P) inhibits macrophage apoptosis by stimulating STAT3 activity and survivin expression

    Feuerborn, R., Becker, S., Potì, F., Nagel, P., Brodde, M., Schmidt, H., Christoffersen, Christina, Ceglarek, U., Burkhardt, R. & Nofer, J., Feb 2017, In: Atherosclerosis. 257, p. 29-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of Atherosclerosis

    Pedersen, A. A., Pedersen, T. X., Junker, N., Christoffersen, Christina, Bartels, Emil Daniel, Madsen, M., Nielsen, Carsten Haagen & Nielsen, L. B., Sep 2016, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 36, 9, p. 1782-1790 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Identification of Glomerular and Plasma Apolipoprotein M as Novel Biomarkers in Glomerular Disease

    Drexler, Y., Molina, J., Elfassy, T., Ma, R., Christoffersen, Christina, Kurano, M., Yatomi, Y., Mariani, L. H., Contreras, G., Merscher, S. & Fornoni, A., 2023, In: Kidney International Reports. 8, 4, p. 884-897

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Impaired LDL Receptor-Related Protein 1 Translocation Correlates with Improved Dyslipidemia and Atherosclerosis in apoE-Deficient Mice

    Gordts, P. L. S. M., Bartelt, A., Nilsson, S. K., Annaert, W., Christoffersen, Christina, Nielsen, L. B., Heeren, J. & Roebroek, A. J. M., 2012, In: P L o S One. 7, 6, p. e38330

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Impaired endothelial barrier function in apolipoprotein M-deficient mice is dependent on sphingosine-1-phosphate receptor 1

    Christensen, P. M., Liu, C. H., Swendeman, S. L., Obinata, H., Qvortrup, Klaus, Nielsen, L. B., Hla, T., Di Lorenzo, A. & Christoffersen, Christina, Jun 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 6, p. 2351-2359 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Increased cardiac BNP expression associated with myocardial ischemia

    Goetze, Jens P. , Christoffersen, Christina, Perko, M., Arendrup, H., Rehfeld, Jens Frederik, Kastrup, J. & Nielsen, L. B., Jun 2003, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 17, 9, p. 1105-7 3 p.

    Research output: Contribution to journal › Journal article › Research

  16. Published

    Increased plasma apoM levels impair triglyceride turnover in mice

    Hajny, Stefan, Borup, A., Elsoe, S. & Christoffersen, Christina, 2021, In: B B A - Molecular and Cell Biology of Lipids. 1866, 9, 9 p., 158969.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Induction of atherosclerosis in mice and hamsters without germline genetic engineering

    Bjørklund, M. M., Hollensen, A. K., Hagensen, M. K., Dagnæs-Hansen, F., Christoffersen, Christina, Mikkelsen, J. G. & Bentzon, J. F., 23 May 2014, In: Circulation Research. 114, 11, p. 1684-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Isolation and characterization of human apolipoprotein M-containing lipoproteins

    Christoffersen, Christina, Nielsen, L. B., Axler, O., Andersson, A., Johnsen, A. H. & Dahlbäck, B., Aug 2006, In: Journal of Lipid Research. 47, 8, p. 1833-43 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    KIDNEY DERIVED APOM AND ITS ROLE IN ACUTE KIDNEY INJURY

    Bisgaard, Line, Christensen, P. M., Fuchtbauer, E., Nielsen, L. B. & Christoffersen, Christina, 2021, In: Nephrology Dialysis Transplantation. 36, Suppl. 1, p. 240-240 MO339.

    Research output: Contribution to journal › Conference abstract in journal › Research

  20. Published

    Kidney derived apolipoprotein M and its role in acute kidney injury

    Bisgaard, Line, Christensen, P. M., Oh, J., Torta, F., Füchtbauer, E. M., Nielsen, L. B. & Christoffersen, Christina, 2024, In: Frontiers in Pharmacology. 15, 1328259.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Left ventricular structure and function in patients with chronic kidney disease assessed by 3D echocardiography: the CPH-CKD ECHO study

    Christensen, J., Landler, N. E., Olsen, F. J., Feldt-Rasmussen, Bo, Hansen, Ditte, Kamper, A. L., Christoffersen, Christina, Ballegaard, E. L. F., Sørensen, I. M. H., Bjergfelt, S. S., Seidelin, E., Bro, S. & Biering-Sørensen, Tor, 2022, In: International Journal of Cardiovascular Imaging. 38, 6, p. 1233–1244 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Long-Acting Neurotensin Synergizes With Liraglutide to Reverse Obesity Through a Melanocortin-Dependent Pathway

    Ratner, C., He, Z., Grunddal, Kaare Villum, Skov, Louise Julie, Hartmann, Bolette, Zhang, F., Feuchtinger, A., Bjerregaard, Anette, Christoffersen, Christina, Tschöp, M. H., Finan, B., DiMarchi, R. D., Leinninger, G. M., Williams, K. W., Clemmensen, Christoffer & Holst, Birgitte, 2019, In: Diabetes. 68, 6, p. 1329-1340

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Loss of Function of GALNT2 Lowers High-Density Lipoproteins in Humans, Nonhuman Primates, and Rodents

    Khetarpal, S. A., Schjoldager, K. T., Christoffersen, C., Raghavan, A., Edmondson, A. C., Reutter, H. M., Ahmed, B., Ouazzani, R., Peloso, G. M., Vitali, C., Zhao, W., Somasundara, A. V. H., Millar, J. S., Park, Y., Fernando, G., Livanov, V., Choi, S., Noé, E., Patel, P., Ho, S. P. & 12 others, Kirchgessner, T. G., Wandall, Hans H., Hansen, Lars, Bennett, Eric Paul, Vakhrushev, Sergey, Saleheen, D., Kathiresan, S., Brown, C. D., Abou Jamra, R., LeGuern, E., Clausen, Henrik & Rader, D. J., 9 Aug 2016, In: Cell Metabolism. 24, 2, p. 234-245 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    METABOLIC PROFILING AS A MARKER OF CARDIOVASCULAR DISEASE AND ARTERIAL CALCIFICATION IN THE COPENHAGEN CHRONIC KIDNEY DISEASE COHORT

    Soerensen, I. M. H., Bisgaard, Line, Bjergfelt, S. S., Ballegaard, E. L. F., Biering-Sørensen, Tor, Landler, N. E., Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Bro, S. & Christoffersen, Christina, 2021, In: Nephrology Dialysis Transplantation. 36, Suppl. 1, 2 p., FC060.

    Research output: Contribution to journal › Conference abstract in journal › Research

  25. Published

    Molecular Characterization of Microvesicular and Macrovesicular Steatosis Shows Widespread Differences in Metabolic Pathways

    Kristiansen, M., Veidal, S. S., Christoffersen, Christina, Jelsing, J. & Rigbolt, K. T. G., 2019, In: Lipids. 54, 1, p. 109-115

    Research output: Contribution to journal › Journal article › Research › peer-review

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