Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The effects of L-arabinose on intestinal sucrase activity: dose-response studies in vitro and in humans

    Krog-Mikkelsen, I., Hels, O., Tetens, Inge , Holst, Jens Juul, Andersen, Jens Rikardt & Bukhave, K., 2011, In: American Journal of Clinical Nutrition. 94, 2, p. 472-478 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A low glycemic index diet does not affect postprandial energy metabolism but decreases postprandial insulinemia and increases fullness ratings in healthy women

    Krog-Mikkelsen, I., Sloth, B., Dimitrov, D., Tetens, Inge , Björck, I., Flint, A., Holst, Jens Juul, Astrup, A., Elmstähl, H. & Raben, Anne, 2011, In: Journal of Nutrition. 141, 9, p. 1679-1684 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Influence of erythropoietin on cognitive performance during experimental hypoglycemia in patients with type 1 diabetes mellitus: A Randomized Cross-Over Trial

    Kristensen, Peter Lommer, Pedersen-Bjergaard, Ulrik, Kjær, T. W., Olsen, N. V., Dela, Flemming, Holst, Jens Juul, Faber, Jens, Tarnow, L. & Thorsteinsson, B., 5 Apr 2013, In: P L o S One. 8, 4, p. 1-8 8 p., e59672.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Impact of the TCF7L2 genotype on risk of hypoglycaemia and glucagon secretion during hypoglycaemia

    Kristensen, P. L., Pedersen-Bjergaard, Ulrik, Due-Andersen, R., Høi-Hansen, T., Grimmeshave, L., Lyssenko, V., Groop, L., Holst, Jens Juul, Vaag, Allan & Thorsteinsson, B., 2016, In: Endocrine Connections. 5, 6, p. 53-60 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Effects of a Low-Carbohydrate-High-Protein Pre-Exercise Meal in Type 1 Diabetes—a Randomized Crossover Trial

    Kristensen, K. B., Ranjan, A. G., Mccarthy, O. M., Holst, Jens Juul, Bracken, R. M., Nørgaard, Kirsten & Schmidt, S., 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 1, p. 208–216 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Similar incretin secretion in obese and non-obese Japanese subjects with type 2 diabetes

    Kozawa, J., Okita, K., Imagawa, A., Iwahashi, H., Holst, Jens Juul, Yamagata, K. & Shimomura, I., 12 Mar 2010, In: Biochemical and Biophysical Research Communications. 393, 3, p. 410-3 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding.

    Korner, J., Bessler, M., Inabnet, W., Taveras, C. & Holst, Jens Juul, 2007, In: Surgery for Obesity and Related Diseases. 3, 6, p. 597-601 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition

    Kootte, R. S., Levin, E., Salojärvi, J., Smits, L. P., Hartstra, A. V., Udayappan, S. D., Hermes, G., Bouter, K. E., Koopen, A. M., Holst, J. J., Knop, F. K., Blaak, E. E., Zhao, J., Smidt, H., Harms, A. C., Hankemeijer, T., Bergman, J. J. G. H. M., Romijn, H. A., Schaap, F. G., Olde Damink, S. W. M. & 8 others, Ackermans, M. T., Dallinga-Thie, G. M., Zoetendal, E., de Vos, W. M., Serlie, M. J., Stroes, E. S. G., Groen, A. K. & Nieuwdorp, M., Oct 2017, In: Cell Metabolism. 26, 4, p. 611-619.e6 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Exogenous glucagon-like peptide-2 (GLP-2) augments GLP-2 receptor mRNA and maintains proglucagon mRNA levels in resected rats

    Koopmann, M. C., Nelson, D. W., Murali, S. G., Liu, X., Brownfield, M. S., Holst, Jens Juul & Ney, D. M., 30 Apr 2008, In: Journal of Parenteral and Enteral Nutrition. 32, 3, p. 254-65 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Colonic GLP-2 is not sufficient to promote jejunal adaptation in a PN-dependent rat model of human short bowel syndrome

    Koopmann, M. C., Liu, X., Boehler, C. J., Murali, S. G., Holst, Jens Juul & Ney, D. M., 2009, In: Journal of Parenteral and Enteral Nutrition. 33, 6, p. 629-38; discussion 638-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Sustained glucagon-like peptide-2 infusion is required for intestinal adaptation, and cessation reverses increased cellularity in rats with intestinal failure

    Koopmann, M. C., Chen, X., Holst, Jens Juul & Ney, D. M., 1 Dec 2010, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 299, 6, p. G1222-30 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Exogenous glucagon-like peptide-2 (GLP-2) augments GLP-2 receptor mRNA and maintains proglucagon mRNA levels in resected rats

    Koopmann, M. C., Nelson, D. W., Murali, S. G., Liu, X. W., Brownfield, M. S., Holst, Jens Juul & Ney, D. M., 2008, In: Journal of Parenteral and Enteral Nutrition. 32, 3, p. 254-265 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Incretin responses to oral glucose and mixed meal tests and changes in fasting glucose levels during 7 years of follow-up: The Hoorn Meal Study

    Koopman, A. D. M., Rutters, F., Rauh, S. P., Nijpels, G., Holst, Jens Juul, Beulens, J. W., Alssema, M. & Dekker, J. M., 2018, In: PloS one. 13, 1, 13 p., e0191114.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Effect of fecal microbiota transplantation combined with Mediterranean diet on insulin sensitivity in subjects with metabolic syndrome

    Koopen, A. M., Almeida, E. L., Attaye, I., Witjes, J. J., Rampanelli, E., Majait, S., Kemper, M., Levels, J. H. M., Schimmel, A. W. M., Herrema, H., Scheithauer, T. P. M., Frei, W., Dragsted, Lars Ove, Hartmann, Bolette, Holst, Jens Juul, O’Toole, P. W., Groen, A. K. & Nieuwdorp, M., 2021, In: Frontiers in Microbiology. 12, 15 p., 662159.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study

    Koopen, A., Witjes, J., Wortelboer, K., Majait, S., Prodan, A., Levin, E., Herrema, H., Winkelmeijer, M., Aalvink, S., Bergman, J. J. G. H. M., Havik, S., Hartmann, B., Levels, H., Bergh, P-O., van Son, J., Balvers, M., Bastos, D. M., Stroes, E., Groen, A. K., Henricsson, M. & 8 others, Kemper, E. M., Holst, Jens Juul, Strauch, C. M., Hazen, S. L., Backhed, F., De Vos, W. M., Nieuwdorp, M. & Rampanelli, E., 2022, In: Gut. 71, p. 1577-1587 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Differential Effects of Secretin-fragments imply a dual Mechanism of Action for Secretin

    Kofod, H., Thams, P. & Holst, Jens Juul, Feb 1991, In: International Journal of Peptide and Protein Research. 37, 2, p. 134-139 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Secretin uncouples glucose inhibition of glucagon-producing cells resulting in a simultaneous stimulation of both glucagon and insulin release

    Kofod, H., Holst, Jens Juul & Lernmark, A., Dec 1988, In: Regulatory Peptides. 23, 3, p. 315-22 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Effects of acute exercise on pancreatic endocrine function in subjects with type 2 diabetes

    Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul, Pedersen, Bente Klarlund & Solomon, T., Feb 2015, In: Diabetes, Obesity and Metabolism. 17, 2, p. 207-210 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  20. Published

    Small-molecule agonists for the glucagon-like peptide 1 receptor

    Knudsen, L. B., Kiel, D., Teng, M., Behrens, C., Bhumralkar, D., Kodra, J. T., Holst, J. J., Jeppesen, C. B., Johnson, M. D., de Jong, J. C., Jorgensen, A. S., Kercher, T., Kostrowicki, J., Madsen, P., Olesen, P. H., Petersen, J. S., Poulsen, F., Sidelmann, U. G., Sturis, J., Truesdale, L. & 2 others, May, J. & Lau, J., 16 Jan 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 3, p. 937-42 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    GLP-1 derivatives as novel compounds for the treatment of type 2 diabetes: selection of NN2211 for clinical development

    Knudsen, L. B., Agerso, H., Bjenning, C. & Holst, Jens Juul, 2001, In: Drug Future. 26, p. 677-685

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Pancreatic Polypeptide in Parkinson's Disease: A Potential Marker of Parasympathetic Denervation

    Knudsen, K., Hartmann, Bolette, Fedorova, T. D., Østergaard, K., Krogh, K., Møller, N., Holst, Jens Juul & Borghammer, P., 2017, In: Journal of Parkinson's Disease. 7, 4, p. 645-652 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Fatty Liver Among Adolescent Offspring of Women With Type 1 Diabetes (the EPICOM Study)

    Knorr, S., Bytoft, B., Lohse, Z., Boisen, A. B., Clausen, Tine Dalsgaard, Jensen, R. B., Damm, Peter, Beck-Nielsen, H., Holst, Jens Juul, Hartmann, Bolette, Moller, H. J., Hojlund, K., Gravholt, C. H. & Jensen, D. M., 2019, In: Diabetes Care. 42, 8, p. 1560-1568

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Replacing SUs with incretin-based therapies for type 2 diabetes mellitus: challenges and feasibility

    Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, T., Jul 2008, In: I Drugs: the Investigational Drugs Journal. 11, 7, p. 497-501 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?

    Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Vølund, A., Holst, Jens Juul & Krarup, T., 2007, In: Diabetes. 56, 8, p. 1951-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Incretin-based therapy of type 2 diabetes mellitus

    Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2009, In: Current Protein and Peptide Science. 10, 1, p. 46-55 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Increased postprandial responses of GLP-1 and GIP in patients with chronic pancreatitis and steatorrhea following pancreatic enzyme substitution.

    Knop, F. K., Vilsbøll, Tina, Larsen, S., Højberg, P. V., Vølund, A., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 1, p. E324-30

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    The impact of pancreatic enzyme supplementation on postprandial responses of glucagon-like Peptide-2 in patients with chronic pancreatitis and pancreatic exocrine insufficiency

    Knop, Filip Krag, Vilsbøll, Tina, Lund, A., Krarup, T., Holst, Jens Juul & Hornum, Mads, 6 Sep 2010, In: Journal of the Pancreas. 11, 5, p. 489-91 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.

    Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2007, In: Regulatory Peptides. 144, 1-3, p. 123-30 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Unprecedented high insulin secretion in a healthy human subject after intravenous glucagon-like peptide-1: a case report

    Knop, Filip Krag, Lund, Asger Bach, Madsbad, Sten, Holst, Jens Juul, Krarup, T. & Vilsbøll, T., 2014, In: BMC Research Notes. 7, p. 1-6 6 p., 326.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity

    Knop, Filip Krag, Aaboe, K., Vilsbøll, Tina, Vølund, A., Holst, Jens Juul, Krarup, T. & Madsbad, Sten, 2012, In: Diabetes, Obesity and Metabolism. 14, 6, p. 500-510 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus

    Knop, F. K., Vilsbøll, Tina, Madsbad, Sten, Holst, Jens Juul, Krarup, T., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Holst, J. M. & Krarup, T., 1 Apr 2007, In: Diabetologia. 50, 4, p. 797-805 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Replacing SUs with incretin-based therapies for type 2 diabetes mellitus: Challenges and feasibility

    Knop, F. K., Holst, Jens Juul & Vilsbøll, Tina, 2008, In: IDrugs. The Investigational Drugs Journal. 11, 7, p. 497-501 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    No reactive hypoglycaemia after subcutaneous administrations of GLP-1 in lean type 2 diabetic patients and in patients with diabeties secondary to chronic pancreatitis

    Knop, F., Vilsbøll, T., Larsen, S., Holst, Jens Juul & Krarup, T., 2003, In: Diabetes Care. 26, p. 2581-2587

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus

    Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Holst, Jens Juul & Krarup, T., Apr 2007, In: Diabetologia. 50, 4, p. 797-805 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Glucagon suppression during OGTT worsens while suppression during IVGTT sustains alongside development of glucose intolerance in patients with chronic pancreatitis

    Knop, Filip Krag, Vilsbøll, Tina, Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T. M., 24 Sep 2010, In: Regulatory Peptides. 164, 2-3, p. 144-50 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Thirty days of resveratrol supplementation does not affect postprandial incretin hormone responses, but suppresses postprandial glucagon in obese subjects

    Knop, Filip Krag, Konings, E., Timmers, S., Schrauwen, P., Holst, Jens Juul & Blaak, E. E., 11 May 2013, In: Diabetic Medicine. 30, 10, p. 1214-1218 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Gluco-metabolic response to exogenous oxytocin in totally pancreatectomized patients and healthy individuals

    Kliim-Hansen, V., Gether, I. M., Juel, C. T., Ellegaard, A., Pedersen, M. G., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Lund, Asger Bach, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2024, In: Peptides. 179, 5 p., 171242.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol

    Kleberg, K., Jacobsen, A. K., Ferreira, J. G., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik, Holst, Jens Juul, de Araujo, I. E. & Hansen, Harald S., 16 Jan 2015, In: The Journal of Physiology. 593, 8, p. 2097-109 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Exenatide once weekly for alcohol use disorder investigated in a randomized, placebo-controlled clinical trial

    Klausen, M. K., Jensen, M. E., Møller, M., le Dous, N., Jensen, A-M. Ø., Zeeman, V. A., Johannsen, C-F., Lee, A. M., Thomsen, G. K., Macoveanu, J., Fisher, P. M., Gillum, M. P., Jørgensen, N. R., Bergmann, M. L., Enghusen Poulsen, H., Becker, U., Holst, J. J., Benveniste, H., Volkow, N. D., Vollstädt-Klein, S. & 5 others, Miskowiak, Kamilla, Ekstrøm, Claus Thorn, Knudsen, Gitte Moos, Visboll, T. & Fink-Jensen, Anders, 2022, In: JCI insight. 19, 20 p., e159863.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Increased intensity of physical activity stimulates subsequent fat intake

    Klausen, B., Toubro, S., Ranneries, C., Rehfeld, J. F., Holst, Jens Juul, Christensen, N. J. & Astrup, A., 1999, In: International Journal of Obesity. 23, p. 1282-1287

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects

    Kjems, L. L., Holst, Jens Juul, Vølund, A. & Madsbad, Sten, Feb 2003, In: Diabetes. 52, 2, p. 380-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The influence of GLP-1 on glucose-induced insulin secretion: effect on ß-cells sensitivity in type 2 and non-diabetic subjects

    Kjems, L. L., Holst, Jens Juul, Vølund, A. A. & Madsbad, S., 2003, In: Diabetes. 52, p. 380-386

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Development of a glucagon sensitivity test in humans: Pilot data and the GLUSENTIC study protocol

    Kjeldsen, S. A. S., Richter, M. M., Jensen, N. J., Nilsson, M. S. D., Heinz, N., Nybing, J. D., Linden, F. H., Høgh-Schmidt, E., Boesen, M. P., Madsbad, S., Vilstrup, H., Schiødt, F. V., Møller, A., Nørgaard, K., Schmidt, S., Rashu, E. B., Gluud, L. L., Haugaard, S. B., Holst, J. J., Rungby, J. & 1 others, Albrechtsen, Nicolai Jacob Wewer, 2023, In: Peptides. 161, 10 p., 170938.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism

    Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Esser, N., Mongovin, S., Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Ceutz, F. R., Terzic, D., Mark, P. D., Plomgaard, Peter Stendahl, Goetze, Jens P. , Goossens, G. H., Blaak, E. E., Deacon, Carolyn F., Rosenkilde, Mette, Zraika, S., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Research. 5, 9, 15 p., bvab084.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Neprilysin activity is increased in metabolic dysfunction-associated steatotic liver disease and normalizes after bariatric surgery or GLP-1 therapy

    Kjeldsen, S. A. S., Gluud, L. L., Werge, M. P., Pedersen, J. S., Bendtsen, F., Alexiadou, K., Tan, T., Torekov, S. S., Iepsen, E. W., Jensen, N. J., Richter, M. M., Goetze, J. P., Rungby, J., Hartmann, B., Holst, J. J., Holst, B., Holt, J., Gustafsson, F., Madsbad, S., Svane, M. S. & 2 others, Bojsen-Møller, K. N. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: iScience. 26, 11, 13 p., 108190.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Markers of Glucagon Resistance Improve With Reductions in Hepatic Steatosis and Body Weight in Type 2 Diabetes

    Kjeldsen, Sasha Alexandra Sampson, Thomsen, M. N., Skytte, M. J., Samkani, A., Richter, Michael Martin, Frystyk, J., Magkos, Faidon, Hansen, E., Thomsen, Henrik S., Holst, Jens Juul, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of the Endocrine Society. 7, 11, 11 p., bvad122.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Neprilysin inhibition increases plasma glucagon concentrations in humans with possible implications for hepatic amino acid metabolism

    Liver-Alpha-Cell Axis Grp, L. A. G., 2020, In: Diabetologia. 63, SUPPL 1, p. S72-S72 1 p., 144.

    Research output: Contribution to journal › Conference abstract in journal › Research

  49. Published

    Development and evaluation of a glucagon sensitivity test

    Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Nilsson, M. S. D., Nybing, J. D., Linden, F. H., Hogh-Schmidt, E., Boesen, Mikael Ploug, Madsbad, Sten, Vilstrup, H. V. A., Rashu, E. B., Gluud, Lise Lotte, Haugaard, Steen Bendix, Holst, Jens Juul, Rungby, Jørgen & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Diabetologia. 64, SUPPL 1, p. 189-189 365.

    Research output: Contribution to journal › Conference abstract in journal › Research

  50. Accepted/In press

    Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes

    Kizilkaya, H. S., Sørensen, K. V., Madsen, J. S., Lindquist, P., Douros, J. D., Bork-Jensen, J., Berghella, A., Gerlach, P. A., Gasbjerg, L. S., Mokrosiński, J., Mowery, S. A., Knerr, P. J., Finan, B., Campbell, J. E., D’Alessio, D. A., Perez-Tilve, D., Faas, F., Mathiasen, S., Rungby, J., Sørensen, H. T. & 15 others, Vaag, A., Nielsen, J. S., Holm, Jens-Christian, Lauenborg, J., Damm, Peter, Pedersen, Oluf Borbye, Linneberg, Allan René, Hartmann, Bolette, Holst, Jens Juul, Hansen, Torben, Wright, S. C., Lauschke, V. M., Grarup, Niels, Hauser, Alexander Sebastian & Rosenkilde, Mette, 2024, (Accepted/In press) In: Nature Metabolism.

    Research output: Contribution to journal › Letter › Research › peer-review

  51. Published

    Glucagon-like peptide-1 as a treatment for chemotherapy-induced mucositis

    Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul & Poulsen, Steen Seier, 20 Oct 2012, In: Gut.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Exogenous glucagon-like peptide-2 (GLP-2) prevents chemotherapy-induced mucositis in rat small intestine

    Kissow, Hannelouise, Viby, N., Hartmann, Bolette, Holst, Jens Juul, Timm, M., Thim, L. & Poulsen, Steen Seier, 2012, In: Cancer Chemotherapy and Pharmacology. Supplement. 70, 1, p. 39-48 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Glucagon-like peptide-1 (GLP-1) receptor agonism or DPP-4 inhibition does not accelerate neoplasia in carcinogen treated mice

    Kissow, Hannelouise, Hartmann, Bolette, Holst, Jens Juul, Viby, N., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hare, K. J. & Poulsen, Steen Seier, 10 Nov 2012, In: Regulatory Peptides. 179, 1-3, p. 91-100 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Cecal infusion of butyrate increases intestinal cell proliferation in piglets

    Kien, C. L., Blauwiekel, R., Bunn, J. Y., Jetton, T. L., Frankel, W. L. & Holst, Jens Juul, 2007, In: Journal of Nutrition. 137, 4, p. 916-922 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists

    Kielgast, U., Holst, Jens Juul & Madsbad, Sten, Nov 2009, In: Current Diabetes Reviews. 5, 4, p. 266-75 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual ß-cell function

    Kielgast, U., Holst, Jens Juul & Madsbad, Sten, May 2011, In: Diabetes. 60, 5, p. 1599-1607 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function

    Kielgast, U., Krarup, T., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jul 2011, In: Diabetes Care. 34, 7, p. 1463-1468 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Effect of glucagon-like peptide-1 on alpha- and beta-cell function in C-peptide-negative type 1 diabetic patients

    Kielgast, U., Asmar, M., Madsbad, Sten & Holst, Jens Juul, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 5, p. 2492-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Genetic variation within the TRPM5 locus associates with prediabetic phenotypes in subjects at increased risk for type 2 diabetes

    Ketterer, C., Müssig, K., Heni, M., Dudziak, K., Randrianarisoa, E., Wagner, R., Machicao, F., Stefan, N., Holst, Jens Juul, Fritsche, A., Häring, H. & Staiger, H., 2011, In: Metabolism. 60, 9, p. 1325-1333 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Incretin and glucagon levels in adult offspring exposed to maternal diabetes in pregnancy

    Kelstrup, L., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben, Holst, Jens Juul & Damm, Peter, 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1967-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Mechanisms of gastric emptying disturbances in chronic and acute inflammation of the distal gastrointestinal tract

    Keller, J., Beglinger, C., Holst, Jens Juul, Andresen, V. & Layer, P., Nov 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 297, 5, p. G861-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Gastric emptying and disease activity in inflammatory bowel disease

    Keller, J., Binnewies, U., Rösch, M., Holst, Jens Juul, Beglinger, C., Andresen, V. & Layer, P., 2015, In: European Journal of Clinical Investigation. 45, 12, p. 1234-42 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Inhibition of human pancreatic and biliary output but not intestinal motility by physiological intraileal lipid loads.

    Keller, J., Holst, Jens Juul & Layer, P., 2005, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 290, 4, p. G704-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Mechanisms of Gastric Emptying Disturbances in Chronic and Acute Inflammation of the Distal Gastrointestinal Tract

    Keller, J., Beglinger, C., Holst, Jens Juul, Andresen, V. & Layer, P., 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Addition of rye bran and pea fiber to pork meatballs enhances subjective satiety in healthy men, but does not change glycemic or hormonal responses: A randomized crossover meal test study

    Kehlet, U., Kofod, J., Holst, Jens Juul, Ritz, C., Aaslyng, M. D. & Raben, Anne, 2017, In: Journal of Nutrition. 147, 9, p. 1700-1708 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Enteral feeding without pancreatic stimulation.

    Kaushik, N., Pietraszewski, M., Holst, Jens Juul & O'Keefe, S. J. D., 2005, In: Pancreas. 31, 4, p. 353-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Mechanisms behind the superior effects of interval vs continuous training on glycaemic control in individuals with type 2 diabetes: a randomised controlled trial

    Karstoft, K., Winding, K., Knudsen, S. H., James, N. G., Scheel, M. M., Olesen, J., Holst, Jens Juul, Pedersen, Bente Klarlund & Solomon, T., 2014, In: Diabetologia. 57, 10, p. 2081-2093 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Molecular mechanisms of lipoapoptosis and metformin protection in GLP-1 secreting cells

    Kappe, C., Holst, Jens Juul, Zhang, Q. & Sjöholm, A., 12 Oct 2012, In: Biochemical and Biophysical Research Communications. 427, 1, p. 91-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells

    Kappe, C., Patrone, C., Holst, Jens Juul, Zhang, Q. & Sjöholm, A., Mar 2013, In: Journal of Gastroenterology. 48, 3, p. 322-32 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Evidence for paracrine/autocrine regulation of GLP-1-producing cells

    Kappe, C., Zhang, Q., Holst, Jens Juul, Nyström, T. & Sjöholm, A., 15 Nov 2013, In: A J P: Cell Physiology (Online). 305, 10, p. C1041-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Mechanisms of action of a carbohydrate-reduced, high-protein diet in reducing the risk of postprandial hypoglycemia after Roux-en-Y gastric bypass surgery

    Kandel, D., Bojsen-Møller, K. N., Svane, M. S., Samkani, A., Astrup, A., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2019, In: American Journal of Clinical Nutrition. 110, 2, p. 296-304 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Gut transit is associated with gastrointestinal symptoms and gut hormone profile in patients with cirrhosis

    Kalaitzakis, E., Sadik, R., Holst, Jens Juul, Ohman, L. & Björnsson, E., 2008, In: Clinical Gastroenterology and Hepatology. 7, 3, p. 346-52 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat

    Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., de Heuval, E. & Sigalet, D. L., 31 Oct 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-45 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Nutritional effects of the serial transverse enteroplasty procedure in experimental short bowel syndrome

    Kaji, T., Tanaka, H., Wallace, L. E., Kravarusic, D., Holst, Jens Juul & Sigalet, D. L., 2009, In: European Journal of Pediatric Surgery. Supplement. 44, 8, p. 1552-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Temporal changes in the intestinal growth promoting effects of glucagon-like peptide 2 following intestinal resection

    Kaji, T., Tanaka, H., Redstone, H., Wallace, L. E., Holst, Jens Juul & Sigalet, D. L., 2008, In: Journal of Surgical Research. 152, 2, p. 271-80 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat

    Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., Heuval, E. D. & Sigalet, D. L., 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-145 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    The exaggerated glucagon-like peptide-1 response is important for the improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes

    Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Jacobsen, S. H., Worm, Dorte, Hansen, D. L., Kristiansen, V. B., Naver, L., Madsbad, Sten & Holst, Jens Juul, 6 May 2013, In: Diabetes. 62, 9, p. 3044-3052 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Sustained Improvements in Glucose Metabolism Late After Roux-En-Y Gastric Bypass Surgery in Patients with and Without Preoperative Diabetes

    Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Svane, M. S., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 2019, In: Scientific Reports. 9, 1, 10 p., 15154.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Improvements in glucose metabolism early after gastric bypass surgery are not explained by increases in total bile acids and fibroblast growth factor 19 concentrations

    Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Kristiansen, V. B., Wulff, B. S., Rainteau, D., Humbert, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Clausen, T. R., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. E396-406 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Glucose metabolism, gut-brain hormones, and acromegaly treatment: an explorative single centre descriptive analysis

    Jørgensen, N. T., Erichsen, T. M., Jørgensen, M. B., Idorn, T., Feldt-Rasmussen, Bo, Holst, Jens Juul, Feldt-Rasmussen, Ulla & Klose, M., 2023, In: Pituitary. 26, p. 152–163

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance

    Jørgensen, N. B., Jacobsen, S. H., Dirksen, C., Bojsen-Møller, K. N., Naver, L., Hvolris, L., Clausen, T. R., Wulff, B. S., Worm, Dorte, Lindqvist Hansen, D., Madsbad, Sten & Holst, Jens Juul, 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 303, 1, p. E122-31

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Effect of the Incretin Hormones on the Endocrine Pancreas in End-Stage Renal Disease

    Jørgensen, M. B., Idorn, T., Rydahl, C., Hansen, H. P., Bressendorff, I., Brandi, Lisbet, Wewer Albrechtsen, N. J., van Hall, Gerrit, Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 3, p. e564-e574

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Clearance of glucoregulatory peptide hormones during haemodialysis and haemodiafiltration in non-diabetic end-stage renal disease patients

    Jørgensen, M. B., Idorn, T., Knop, Filip Krag, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Mar 2015, In: Nephrology, Dialysis, Transplantation. 30, 3, p. 513-20 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Circulating levels of incretin hormones an amylin in the fasting state and after oral glucose in growth hormone (GH-)deficient patients before and after GH replacement. A placebo controlled study

    Jørgensen, J. O. L., Rosenfalck, A. M., Fisker, S., Nyholm, B., Fineman, M. S., Schmitz, O., Madsbad, S., Holst, Jens Juul & Christiansen, J. S., 2000, In: European Journal of Endocrinology. 143, p. 593-599

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Pros and cons of Roux en-Y gastric bypass surgery in obese patients with type 2 diabetes

    Justinussen, T., Madsbad, Sten, Holst, Jens Juul & Bojsen-Moller, K. N., 2019, In: Expert Review of Endocrinology & Metabolism. 14, 4, p. 243-257

    Research output: Contribution to journal › Review › Research › peer-review

  86. Published

    Structural differences between rye and wheat breads but not total fiber content may explain the lower postprandial insulin response to rye bread

    Juntunen, K. S., Laaksonen, D. E., Autio, K., Niskanen, L. K., Holst, Jens Juul, Savolainen, K. E., Liukkonen, K., Poutanen, K. S. & Mykkänen, H. M., Nov 2003, In: Uden navn. 78, 5, p. 957-64 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Postprandial glucose, insulin and incretin responses to grain products in healthy subjects

    Juntunen, K. S., Lioukkonen, H. K., Poutanen, S. K., Niskanen, K. L., Holst, Jens Juul & Mykkänen, M. H., 2002, In: Am. J. Clin. Nutr.. 75, p. 254-262

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Structural differences between rye and wheat bread but not total fiber content may explain the lower postprandial insulin response to rye bread

    Juntunen, K. S., Laaksonen, D. E., Aitio, K., Niskanen, L. K., Holst, Jens Juul, Savolainen, K. E., Liukkonen, K. H., Poutanen, K. S. & Mykkänen, H. M., 2003, In: Am. J. Clin. Nutr.. 78, p. 957-964

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Influence of acarbose on postprandial insulin requirements in patients with type 1 diabetes

    Juntti-Berggren, L., Pigon, J., Hellström, P. M., Holst, Jens Juul & Efendic, S., 2000, In: Diab Nutr Metab. 13, p. 7-12

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    A 25-year-old woman with type 2 diabetes and liver disease

    Junker, A. E., Gluud, Lise Lotte, Pedersen, J., Langhoff, J. L., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2014, In: Case Reports in Gastroenterology. 8, 3, p. 398-403 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Effects of glucagon-like peptide-1 on glucagon secretion in patients with non-alcoholic fatty liver disease

    Junker, A. E., Gluud, Lise Lotte, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Apr 2016, In: Journal of Hepatology. 64, 4, p. 908–915

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Influence of gastrointestinal factors on glucose metabolism in patients with cirrhosis

    Junker, A. E., Gluud, Lise Lotte, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Oct 2015, In: Journal of Gastroenterology and Hepatology. 30, 10, p. 1522-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Diabetic and nondiabetic patients with nonalcoholic fatty liver disease have an impaired incretin effect and fasting hyperglucagonaemia

    Junker, A. E., Gluud, Lise Lotte, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, May 2016, In: Journal of Internal Medicine. 279, 5, p. 485–493 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Atrial Natriuretic Peptide in the high normal range is associated with lower prevalence of insulin resistance

    Jujić, A., Nilsson, P. M., Persson, M., Holst, Jens Juul, Torekov, Signe Sørensen, Lyssenko, V., Groop, L., Melander, O. & Magnusson, M., 27 Jan 2016, In: The Journal of clinical endocrinology and metabolism. 101, 4, p. 1372-1380 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Endogenous incretin levels and risk of first incident cancer: a prospective cohort study

    Jujic, A., Godina, C., Belting, M., Melander, O., Holst, Jens Juul, Ahlqvist, E., Gomez, M. F., Nilsson, P. M., Jernstrom, H. & Magnusson, M., 2023, In: Scientific Reports. 13, 1, 11 p., 382.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Glucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality: a prospective study

    Jujic, A., Atabaki-Pasdar, N., Nilsson, P. M., Almgren, P., Hakaste, L., Tuomi, T., Berglund, L. M., Franks, P. W., Holst, Jens Juul, Prasad, R. B., Torekov, Signe Sørensen, Ravassa, S., Diez, J., Persson, M., Melander, O., Gomez, M. F., Groop, L., Ahlqvist, E. & Magnusson, M., May 2020, In: Diabetologia. 63, 5, p. 1043-1054

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness

    Jujic, A., Nilsson, P. M., Atabaki-Pasdar, N., Dieden, A., Tuomi, T., Franks, P. W., Holst, Jens Juul, Torekov, Signe Sørensen, Ravassa, S., Diez, J., Persson, M., Ahlqvist, E., Melander, O., Gomez, M. F., Groop, L. & Magnusson, M., 2021, In: Diabetes Care. 44, 1, p. 224-230 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Automated detection of hypoglycemia-induced EEG changes recorded by subcutaneous electrodes in subjects with type 1 diabetes--the brain as a biosensor

    Juhl, C. B., Højlund, K., Elsborg, R., Poulsen, M. K., Selmar, P. E., Holst, Jens Juul, Christiansen, C. & Beck-Nielsen, H., 1 Apr 2010, In: Diabetes Research and Clinical Practice. 88, 1, p. 22-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    A randomised, double-blind, crossover study of the effect of the fluoroquinolone moxifloxacin on glucose levels and insulin sensitivity in young men and women

    Juhl, C. R., Burgdorf, J., Knudsen, C., Lubberding, Anniek Frederike, Veedfald, Simon, Isaksen, Jonas L., Hartmann, Bolette, Frikke-Schmidt, Ruth, Mandrup-Poulsen, Thomas, Holst, Jens Juul, Kanters, Jørgen K. & Torekov, Signe Sørensen, 2023, In: Diabetes, Obesity and Metabolism. 25, 1, p. 98-109

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Short-term treatment with GLP-1 increases pulsatile secretion in type 2 diabetes with no effect on orderliness.

    Juhl, C. B., Schmitz, O., Holst, Jens Juul, Vedhuis, J. & Pørksen, N., 2000, In: Diabetologia. 43, p. 583-588

    Research output: Contribution to journal › Journal article › Research › peer-review

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