Thomas Jespersen

Thomas Jespersen

Professor

Member of:


    1. Published

      The sodium channel activator Lu AE98134 normalizes the altered firing properties of fast spiking interneurons in Dlx5/6+/- mice

      von Schoubye, N. L., Frederiksen, K., Kristiansen, Uffe, Petersen, A. V., Dalby, N. O., Grunnet, M., Jensen, H. S., Jespersen, Thomas, Sohal, V. S. & Perrier, Jean-Francois Marie, 2018, In: Neuroscience Letters. 662, p. 29-35 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    2. Published

      Dynein regulates Kv7.4 channel trafficking from the cell membrane

      van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Pharmacological exploration of the resting membrane potential reserve: Impact on atrial fibrillation

      van der Heyden, M. A. G. & Jespersen, Thomas, 15 Jan 2016, In: European Journal of Pharmacology. 771, p. 56-64 9 p.

      Research output: Contribution to journalReviewResearchpeer-review

    4. Published

      Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada Syndrome mutant

      Yuan, L., Koivumaki, J., Liang, B., Lorentzen, L. G., Tang, C., Andersen, M. N., Svendsen, Jesper Hastrup, Tfelt-Hansen, J., Maleckar, M., Schmitt, Nicole, Olesen, Morten Steen Salling & Jespersen, Thomas, 21 Feb 2014, In: American Journal of Physiology: Heart and Circulatory Physiology. 306, 8, p. H1204-12

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.

      Yuan, L., Koivumäki, J., Liang, B., Lorentzen, Lasse Gøbel, Tang, C., Andersen, M., Svendsen, J., Tfelt-Hansen, Jacob, Maleckar, M., Schmitt, Nicole, Olesen, M. & Jespersen, Thomas, Feb 2014, In: American journal of physiology. Heart and circulatory physiology.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome

      Yang, Y., Yang, Y., Liang, B., Liu, J., Li, J., Grunnet, M., Olesen, S-P., Rasmussen, H. B., Ellinor, P. T., Gao, L., Lin, X., Li, L., Wang, L., Xiao, J., Liu, Y., Liu, Y., Zhang, S., Liang, D., Peng, L., Jespersen, T. & 1 others, Chen, Y., 2010, In: American Journal of Human Genetics. 86, 6, p. 872-80 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome

      Winkel, B. G., Yuan, L., Olesen, Morten Steen Salling, Sadjadieh, G., Wang, Y., Risgaard, B., Jabbari, R., Haunsø, Stig, Holst, A. G., Hollegaard, M. V., Tfelt-Hansen, J. & Jespersen, Thomas, Jun 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 6, p. 1241-1249 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      MR-proANP measured at admission is associated with incident atrial fibrillation in STEMI patients

      Wegener, A., Modin, D., Pedersen, S., Lindberg, S., Pareek, M., Iversen, Kasper, Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2022, In: Heart and Vessels. 37, p. 1906–1913 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology

      Wang, X., Liang, B., Skibsbye, L., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, Aug 2013, In: Journal of Cardiovascular Pharmacology. 62, 2, p. 192-8 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Population-based pediatric reference values for serum parathyroid hormone, vitamin D, calcium, and phosphate in Danish/North-European white children and adolescents

      Vissing Landgrebe, A., Lund, Morten Asp Vonsild, Lausten-Thomsen, U., Frithioff-Bøjsøe, C., Fonvig, Cilius Esmann, Lind Plesner, J., Aas Holm, L., Jespersen, Thomas, Hansen, Torben & Holm, Jens-Christian, 2021, In: Clinica Chimica Acta. 523, p. 483-490

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis

      Tommiska, J., Känsäkoski, J., Skibsbye, L., Vaaralahti, K., Liu, X., Lodge, E. J., Tang, C., Yuan, L., Fagerholm, R., Kanters, J. K., Lahermo, P., Kaunisto, M., Keski-Filppula, R., Vuoristo, S., Pulli, K., Ebeling, T., Valanne, L., Sankila, E-M., Kivirikko, S., Lääperi, M. & 15 others, Casoni, F., Giacobini, P., Phan-Hug, F., Buki, T., Tena-Sempere, M., Pitteloud, N., Veijola, R., Lipsanen-Nyman, M., Kaunisto, K., Mollard, P., Andoniadou, C. L., Hirsch, J. A., Varjosalo, M., Jespersen, Thomas & Raivio, T., 3 Nov 2017, In: Nature Communications. 8, 1, 11 p., 1289.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      Cardiac channelopathies and sudden infant death syndrome

      Tfelt-Hansen, J., Winkel, B. G., Grunnet, Morten & Jespersen, Thomas, 2011, In: The Cardiology. 119, 1, p. 21-33 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Arvelige hjertesygdomme forårsaget af natriumkanalmutationer

      Tfelt-Hansen, J., Olesen, Søren-Peter, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2009, In: Ugeskrift for læger. 171, 15, p. 1261-5 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Inherited Cardiac Diseases Caused by Mutations in the Nav1.5 Sodium Channel

      Tfelt-Hansen, J., Winkel, B. G., Grunnet, Morten & Jespersen, Thomas, 2009, In: Cardiovascular Electrophysiology.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Inherited cardiac diseases caused by mutations in the Nav1.5 sodium channel.

      Tfelt-Hansen, Jacob, Winkel, B., Grunnet, Morten & Jespersen, Thomas, Oct 2009, In: Journal of Cardiovascular Electrophysiology.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A

      Tfelt-Hansen, J., Jespersen, Thomas, Hofman-Bang, J., Rasmussen, Hanne Borger, Cedergreen, P., Skovby, F., Abriel, H., Svendsen, Jesper Hastrup, Olesen, S., Christiansen, M. & Haunso, S., 2009, In: Canadian Journal of Cardiology. 25, 3, p. 156-60 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Biophysical characterization of KV3.1 potassium channel activating compounds

      Taskin, B., von Schoubye, N. L., Sheykhzade, Majid, Bastlund, J. F., Grunnet, M. & Jespersen, Thomas, 5 Jul 2015, In: European Journal of Pharmacology. 758, p. 164-170 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms

      Tang, C., Skibsbye, L., Yuan, L., Bentzen, Bo Hjorth & Jespersen, Thomas, Oct 2015, In: General Physiology and Biophysics. 34, 4, p. 383-92 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Cause-specific mortality in children and young adults with diabetes mellitus: A Danish nationwide cohort study

      Svane, Jesper, Lynge, T. H., Pedersen-Bjergaard, Ulrik, Jespersen, Thomas, Gislason, Gunnar Hilmar, Risgaard, B., Winkel, B. G. & Tfelt-Hansen, Jacob, 2021, In: European Journal of Preventive Cardiology. 28, 2, p. 159-165

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts

      Soltysinska, E., Olesen, Søren-Peter, Christ, T., Wettwer, E., Varró, A., Grunnet, Morten & Jespersen, Thomas, 2009, In: Pflügers Archiv: European Journal of Physiology. 459, 1, p. 11-23 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      The Acetylcholine-Activated Potassium Current Inhibitor XAF-1407 Terminates Persistent Atrial Fibrillation in Goats

      Sobota, V., Gatta, G., van Hunnik, A., van Tuijn, I., Kuiper, M., Milnes, J., Jespersen, Thomas, Schotten, U. & Verheule, S., 2021, In: Frontiers in Pharmacology. 11, 13 p., 608410.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Inhibition of Adenosine Pathway Alters Atrial Electrophysiology and Prevents Atrial Fibrillation

      Soattin, Luca, Lubberding, Anniek Frederike, Bentzen, Bo Hjorth, Christ, T. & Jespersen, Thomas, 2020, In: Frontiers in Physiology. 11, 14 p., 493.

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

      Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria

      Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, 1 Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-67 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During beta-Adrenergic and Muscarinic Receptor Activation

      Skibsbye, L., Bengaard, A. K., Uldum-Nielsen, A. M., Boddum, K., Christ, T. & Jespersen, Thomas, 2018, In: Frontiers in Physiology. 9

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarisation in human atria.

      Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-167 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Refractoriness in human atria: Time and voltage dependence of sodium channel availability

      Skibsbye, L., Jespersen, Thomas, Christ, T., Maleckar, M. M., van den Brink, J., Tavi, P. & Koivumäki, J. T., Dec 2016, In: Journal of Molecular and Cellular Cardiology. 101, p. 26-34 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Pharmacological inhibition of I-K1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness

      Skarsfeldt, M. A., Carstensen, Helena, Skibsbye, L., Tang, C., Buhl, Rikke, Bentzen, Bo Hjorth & Jespersen, Thomas, Apr 2016, In: Physiological Reports. 4, 8, 11 p., e12734.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      KCNQ4 channel activation by BMS-204352 and retigabine

      Schrøder, R. L. K., Jespersen, Thomas, Christophersen, P., Strøbaek, D., Jensen, B. S. & Olesen, Poul, 1 Jun 2001, In: Neuropharmacology. 40, 7, p. 888-98 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Ventricular Arrhythmias in First Acute Myocardial Infarction: Epidemiology, Mechanisms, and Interventions in Large Animal Models

      Sattler, S. M., Skibsbye, L., Dr Linz, Dominik Karl, Lubberding, Anniek Frederike, Tfelt-Hansen, Jacob & Jespersen, Thomas, 2019, In: Frontiers in Cardiovascular Medicine. 6, 14 p., 158.

      Research output: Contribution to journalReviewResearchpeer-review

    31. Published

      Amiodarone Treatment in the Early Phase of Acute Myocardial Infarction Protects Against Ventricular Fibrillation in a Porcine Model

      Sattler, Stefan M, Lubberding, Anniek Frederike, Skibsbye, L., Jabbari, R., Wakili, R., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2019, In: Journal of Cardiovascular Translational Research. 12, 4, p. 321-330

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Effect of the antipsychotic drug haloperidol on arrhythmias during acute myocardial infarction in a porcine model

      Sattler, Stefan M, Lubberding, Anniek Frederike, Kristensen, C. B., Møgelvang, R., Blanche, Paul Frédéric, Fink-Jensen, Anders, Engstrøm, Thomas, Kääb, S., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2020, In: IJC Heart and Vasculature. 26, 100455.

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published
    34. Published

      Increased fibroblast accumulation in the equine heart following persistent atrial fibrillation

      Saljic, Arnela, Fenner, Merle Friederike, Winters, J., Flethøj, M., Eggert Eggertsen, C., Carstensen, Helena, Nissen, Sarah Dalgas, Melis Hesselkilde, E., van Hunnik, A., Schotten, U., Sørensen, U., Jespersen, Thomas, Verheule, S. & Buhl, Rikke, 2021, In: IJC Heart and Vasculature. 35, 100842.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Impact of arrhythmogenic calmodulin variants on small conductance Ca2+-activated K+ (SK3) channels

      Saljic, Arnela, Muthukumarasamy, K. M., la Cour, J. M., Boddum, K., Grunnet, Morten, Berchtold, Martin Werner & Jespersen, Thomas, 2019, In: Physiological Reports. 7, 19, 13 p., e14210.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      In vivo knockdown of SK3 channels using antisense oligonucleotides protects against atrial fibrillation in rats

      Saljic, Arnela, Soattin, Luca, Trachsel, D. S., Boddum, K. & Jespersen, Thomas, Oct 2020, In: Journal of Molecular and Cellular Cardiology. 147, p. 18-26

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      Anti-arrhythmic investigations in large animal models of atrial fibrillation

      Saljic, Arnela, Jespersen, Thomas & Buhl, Rikke, 2022, In: British Journal of Pharmacology. 179, 5, p. 838-858

      Research output: Contribution to journalReviewResearchpeer-review

    38. Published

      Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins.

      Rougier, J., van Bemmelen, M. X., Bruce, M. C., Jespersen, Thomas, Gavillet, B., Apothéloz, F., Cordonier, S., Staub, O., Rotin, D. & Abriel, H., 2004, In: American Journal of Physiology: Cell Physiology. 288, 3, p. C692-701

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Change in global longitudinal strain following acute coronary syndrome and subsequent risk of heart failure

      Ravnkilde, K., Skaarup, K. G., Grove, G. L., Modin, D., Nielsen, A. B., Falsing, M. M., Iversen, A. Z., Pedersen, S., Fritz-Hansen, T., Galatius, S., Jespersen, Thomas, Shah, A., Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2021, In: International Journal of Cardiovascular Imaging. 37, p. 3193–3202

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Utility of left atrial strain for predicting atrial fibrillation following ischemic stroke

      Rasmussen, S. M. A., Olsen, F. J., Jorgensen, P. G., Fritz-Hansen, T., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2019, In: International Journal of Cardiovascular Imaging. 35, 9, p. 1605-1613

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation

      Poulet, C., Wettwer, E., Grunnet, Morten, Jespersen, Thomas, Fabritz, L., Matschke, K., Knaut, M. & Ravens, U., 29 Jun 2015, In: PLOS ONE. 10, 6, p. 1-19 19 p., e0131432.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Published

      Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome.

      Petitprez, S., Jespersen, Thomas, Pruvot, E., Keller, D. I., Corbaz, C., Schläpfer, J., Abriel, H. & Kucera, J. P., 2008, In: Cardiovascular Research. 78, 3, p. 494-504 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Muscarinic Receptor Activation Reduces Force and Arrhythmias in Human Atria Independent of IK,ACh

      Petersen, J., Castro, L., Bengaard, A. K. P., Pecha, S., Ismaili, D., Schulz, C., Sahni, J., Steenpass, A., Meier, C., Reichenspurner, H., Jespersen, Thomas, Eschenhagen, T. & Christ, T., 2022, In: Journal of Cardiovascular Pharmacology. 79, 5, p. 678-686

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Subtype-specific, bi-component inhibition of SK channels by low internal pH.

      Peitersen, T., Jespersen, Thomas, Jorgensen, N. K., Olesen, Søren-Peter & Grunnet, Morten, 2006, In: Biochemical and Biophysical Research Communications. 343, 3, p. 943-9 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Clinical Implications of SCN10A Loss-of-Function Variants in 169 610 Exomes Representing the General Population.

      Paludan-Müller, Christian, Larsen, S., Ahlberg, G., Monfort, L. M., Andreasen, L., Svendsen, Jesper Hastrup, Jespersen, Thomas, Bundgård, Henning, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2022, In: Circulation. Genomic and precision medicine. 15, 1, p. 83-85 3 p., e003574.

      Research output: Contribution to journalLetterResearchpeer-review

    46. Published

      Time matters: characterization of fibroblast-like cells harvested from pig profundus tendon stored at room temperature at different postmortem time intervals

      Ozhathil, Lijo Cherian, Chen, Y., Nissen, Sarah Dalgas, Banner, Jytte, Tfelt-Hansen, Jacob & Jespersen, Thomas, 2022, In: In Vitro Cellular and Developmental Biology - Animal. 58, p. 633–637

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Screening of KCNN3 in patients with early-onset lone atrial fibrillation

      Olesen, M. S., Jabbari, J., Holst, A. G., Nielsen, J. B., Steinbrüchel, D. A., Jespersen, T., Haunsø, Stig, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2011, In: Europace. 13, 7, p. 963-967 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Mutations in sodium channel {beta}-subunit SCN3B are associated with early-onset lone atrial fibrillation

      Olesen, M. S., Jespersen, Thomas, Nielsen, J. B., Liang, B., Møller, D. V., Hedley, P., Christiansen, M., Varro, A., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole & Svendsen, Jesper Hastrup, 2011, In: Cardiovascular Research. 89, 4, p. 786-793 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      High Prevalence of Long QT Syndrome Associated SCN5A Variants in Patients with Early-Onset Lone Atrial Fibrillation

      Olesen, M. S., Yuan, L., Liang, B., Holst, A. G., Nielsen, N., Nielsen, J. B., Hedley, P. L., Christiansen, M., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole, Jespersen, Thomas & Svendsen, Jesper Hastrup, 2012, In: Circulation: Cardiovascular Genetics. 5, 4, p. 450-459 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    50. Published

      A Novel Nonsense Variant in Nav1.5 Cofactor MOG1 Eliminates Its Sodium Current Increasing Effect and May Increase the Risk of Arrhythmias

      Olesen, M. S., Jensen, N. F., Holst, A. G., Nielsen, J. B., Tfelt-Hansen, Jacob, Jespersen, Thomas, Sajadieh, Ahmad, Haunsø, Stig, Lund, J. T., Callø, Kirstine, Schmitt, Nicole & Svendsen, Jesper Hastrup, 26 May 2011, In: Canadian Journal of Cardiology. 27, 4, p. 523.e17-23

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published
    52. Published
    53. Published

      Muscarinic acetylcholine receptors M2 are upregulated in the atrioventricular nodal tract in horses with a high burden of second-degree atrioventricular block

      Nissen, Sarah Dalgas, Saljic, Arnela, Carstensen, Helena, Braunstein, T. H., Hesselkilde, E. M., Kjeldsen, S. T., Hopster-Iversen, Charlotte, D’Souza, A., Jespersen, Thomas & Buhl, Rikke, 2023, In: Frontiers in Cardiovascular Medicine. 10, 10 p., 1102164.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Published

      Electrocardiographic characteristics of trained and untrained standardbred racehorses

      Nissen, Sarah Dalgas, Weis, R., Krag-Andersen, E. K., Hesselkilde, E. M., Isaksen, Jonas L., Carstensen, Helena, Kanters, Jørgen K., Dr Linz, Dominik Karl, Sanders, P., Hopster-Iversen, Charlotte, Jespersen, Thomas, Pehrson, S. & Buhl, Rikke, 2022, In: Journal of Veterinary Internal Medicine. 36, 3, p. 1119-1130

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. Published

      Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure

      Nissen, J. D., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Diness, Jonas Goldin, Diness, T. G., Jespersen, Thomas & Grunnet, Morten, 2012, In: Journal of Cardiovascular Pharmacology. 59, 2, p. 142-150 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. Published

      Pharmacologically induced long QT type 2 can be rescued by activation of IKs with benzodiazepine R-L3 in isolated guinea pig cardiomyocytes

      Nissen, J. D., Diness, Jonas Goldin, Diness, T. G., Hansen, R. S., Grunnet, Morten & Jespersen, Thomas, 2009, In: Journal of Cardiovascular Pharmacology. 54, 2, p. 169-77 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    57. Published

      Pharmacological rescue of mutated K(v)3.1 ion-channel linked to progressive myoclonus epilepsies

      Munch, A. S., Saljic, Arnela, Boddum, K., Grunnet, Morten, Hougaard, C. & Jespersen, Thomas, 2018, In: European Journal of Pharmacology. 833, p. 255-262

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Intrinsic Electrical Remodeling Underlies Atrioventricular Block in Athletes

      Mesirca, P., Nakao, S., Nissen, S. D., Forte, G., Anderson, C., Trussell, T., Li, J., Cox, C., Zi, M., Logantha, S., Yaar, S., Cartensen, H., Bidaud, I., Stuart, L., Soattin, L., Morris, G. M., Da Costa Martins, P. A., Cartwright, E. J., Oceandy, D., Mangoni, M. E. & 5 others, Jespersen, Thomas, Buhl, Rikke, Dobrzynski, H., Boyett, M. R. & D'Souza, A., 2021, In: Circulation Research. 129, 1, p. E1-E20

      Research output: Contribution to journalJournal articleResearchpeer-review

    59. Published

      From CMR Image to Patient-Specific Simulation and Population-Based Analysis: Tutorial for an Openly Available Image-Processing Pipeline

      Marciniak, M., Arevalo, H., Tfelt-Hansen, Jacob, Jespersen, Thomas, Jabbari, R., Glinge, C., Ahtarovski, K. A., Vejlstrup, N., Engstrøm, Thomas, Maleckar, M. M. & McLeod, K., 1 Jan 2017, Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges - 7th International Workshop, STACOM 2016 Held in Conjunction with MICCAI 2016, Revised Selected Papers. Springer, p. 106-117 12 p. (Lecture Notes in Computer Science, Vol. 10124 LNCS).

      Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    60. Published

      A Multiple Kernel Learning Framework to Investigate the Relationship Between Ventricular Fibrillation and First Myocardial Infarction

      Marciniak, M., Arevalo, H., Tfelt-Hansen, Jacob, Ahtarovski, K. A., Jespersen, Thomas, Jabbari, R., Glinge, C., Vejlstrup, N., Engstrøm, Thomas, Maleckar, M. M. & McLeod, K., 1 Jan 2017, Functional Imaging and Modelling of the Heart: 9th International Conference, FIMH 2017, Toronto, ON, Canada, June 11-13, 2017, Proceedings. Springer, p. 161-171 11 p. (Lecture Notes in Computer Science, Vol. 10263 LNCS).

      Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    61. Published

      Combined In-silico and Machine Learning Approaches Toward Predicting Arrhythmic Risk in Post-infarction Patients

      Maleckar, M. M., Myklebust, L., Uv, J., Florvaag, P. M., Strøm, V., Glinge, C., Jabbari, R., Vejlstrup, N., Engstrøm, Thomas, Ahtarovski, K., Jespersen, Thomas, Tfelt-Hansen, Jacob, Naumova, V. & Arevalo, H., 2021, In: Frontiers in Physiology. 12, 745349.

      Research output: Contribution to journalJournal articleResearchpeer-review

    62. Published

      Nationwide Burden of Sudden Cardiac Death: A Study of 54,028 Deaths in Denmark

      Lynge, T. H., Risgaard, B., Banner, Jytte, Nielsen, J. L., Jespersen, Thomas, Stampe, N. K., Albert, C. M., Winkel, B. G. & Tfelt-Hansen, Jacob, 2021, In: Heart Rhythm. 18, 10, p. 1657-1665

      Research output: Contribution to journalJournal articleResearchpeer-review

    63. Published

      Kredsløbet ændres ved overvægt i barndommen

      Lund, Morten Asp Vonsild, Holm, Jens-Christian, Jespersen, Thomas & von Holstein-Rathlou, Niels-Henrik, 2017, In: Ugeskrift for Laeger. 2018, 6, p. 2-6 5 p., V03170265.

      Research output: Contribution to journalJournal articleResearchpeer-review

    64. E-pub ahead of print

      Glucagon-like peptide-1 increases heart rate by a direct action on the sinus node

      Lubberding, A. F., Veedfald, S., Achter, J. S., Nissen, S. D., Soattin, L., Sorrentino, A., Torres Vega, E., Linz, B., Eggertsen, C. H. E., Mulvey, J., Toräng, S., Larsen, S. A., Nissen, A., Petersen, L. G., Erbil Bilir, S., Bentzen, B. H., Rosenkilde, M. M., Hartmann, B., Lilleør, T. N. B., Qazi, S. & 6 others, Møller, Christian H., Tfelt-Hansen, Jacob, Sattler, Stefan M, Jespersen, Thomas, Holst, Jens Juul & Lundby, Alicia, 2024, (E-pub ahead of print) In: Cardiovascular Research. 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    65. Published

      Comparison of hemodynamics, cardiac electrophysiology and ventricular arrhythmia in an open and a closed chest porcine model of acute myocardial infarction

      Lubberding, Anniek Frederike, Sattler, Stefan M, Flethøj, M., Tfelt-Hansen, Jacob & Jespersen, Thomas, 2020, In: American Journal of Physiology: Heart and Circulatory Physiology. 318, 2, p. H391-H400

      Research output: Contribution to journalJournal articleResearchpeer-review

    66. Published

      Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V

      Lubberding, Anniek Frederike, Zhang, J., Lundh, M., Nielsen, Thomas Svava, Søndergaard, M. S., Villadsen, M., Skovhøj, E. Z., Boer, G. A., Hansen, J. B., Thomsen, Morten Bækgaard, Treebak, Jonas Thue, Holst, Jens Juul, Kanters, Jørgen K., Mandrup-Poulsen, Thomas, Jespersen, Thomas, Emanuelli, Brice & Torekov, Signe Sørensen, 2021, In: Scientific Reports. 11, 1, 14 p., 12253.

      Research output: Contribution to journalJournal articleResearchpeer-review

    67. Published

      Arrhythmia development during inhibition of small-conductance calcium-activated potassium channels in acute myocardial infarction in a porcine model

      Lubberding, Anniek Frederike, Sattler, Stefan M, Grunnet, Morten, Sørensen, U. S., Tfelt-Hansen, Jacob & Jespersen, Thomas, Oct 2019, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 21, 10, p. 1584–1593

      Research output: Contribution to journalJournal articleResearchpeer-review

    68. Published

      Pulmonary vein firing initiating atrial fibrillation in the horse: Oversized dimensions but similar mechanisms

      Dr Linz, Dominik Karl, Hesselkilde, E., Kutieleh, R., Jespersen, Thomas, Buhl, Rikke & Sanders, P., 2020, In: Journal of Cardiovascular Electrophysiology. 31, 5, p. 1211-1212

      Research output: Contribution to journalJournal articleResearchpeer-review

    69. Published

      Personalized management of sleep apnea in patients with atrial fibrillation: An interdisciplinary and translational challenge

      Dr Linz, Dominik Karl, Linz, Benedikt Maximilian, Dobrev, D., Baumert, M., Hendriks, J. M., Pepin, J. L. & Jespersen, Thomas, 2021, In: IJC Heart and Vasculature. 35, 100843.

      Research output: Contribution to journalEditorialResearchpeer-review

    70. Published

      Pharmacological inhibition of acetylcholine-regulated potassium current (IK,ACh) prevents atrial arrhythmogenic changes in a rat model of repetitive obstructive respiratory events

      Linz, Benedikt Maximilian, Thostrup, A. H., Saljic, Arnela, Rombouts, K., Hertel, Julie Norup, Hohl, M., Milnes, J., Tfelt-Hansen, Jacob, Dr Linz, Dominik Karl & Jespersen, Thomas, Feb 2022, In: Heart Rhythm O2. 3, 1, p. 97-104

      Research output: Contribution to journalJournal articleResearchpeer-review

    71. Published

      Mechanisms and Therapeutic Opportunities in Atrial Fibrillation in Relationship to Alcohol Use and Abuse

      Linz, Benedikt Maximilian, Hertel, Julie Norup, Jespersen, Thomas & Dr Linz, Dominik Karl, 2022, In: Canadian Journal of Cardiology. 38, 9, p. 1352-1363

      Research output: Contribution to journalReviewResearchpeer-review

    72. Published

      Repeated exposure to transient obstructive sleep apnea–related conditions causes an atrial fibrillation substrate in a chronic rat model

      Linz, Benedikt Maximilian, Hohl, M., Lang, L., Wong, D. W. L., Nickel, A. G., De La Torre, C., Sticht, C., Wirth, K., Boor, P., Maack, C., Speer, T., Jespersen, Thomas, Schotten, U., Sanders, P., Böhm, M. & Dr Linz, Dominik Karl, 2021, In: Heart Rhythm. 18, 3, p. 455-464

      Research output: Contribution to journalJournal articleResearchpeer-review

    73. Published

      Sleep apnea and atrial fibrillation: challenges in clinical and translational research

      Linz, Benedikt Maximilian, Hertel, Julie Norup, Hendriks, J., Saljic, Arnela, Dobrev, D., Baumert, M., Jespersen, Thomas & Dr Linz, Dominik Karl, 2022, In: Expert Review of Cardiovascular Therapy. 20, 2, p. 101-109

      Research output: Contribution to journalJournal articleResearchpeer-review

    74. Published

      Inhibition of sodium-proton-exchanger subtype 3-mediated sodium absorption in the gut: A new antihypertensive concept

      Linz, Benedikt Maximilian, Saljic, Arnela, Hohl, M., Gawalko, M., Jespersen, Thomas, Sanders, P., Bohm, M. & Dr Linz, Dominik Karl, 2020, In: IJC Heart and Vasculature. 29, 7 p., 100591.

      Research output: Contribution to journalReviewResearchpeer-review

    75. Published

      Arrhythmogenic mechanisms of acute obstructive respiratory events in a porcine model of drug-induced Long-QT

      Linz, Benedikt Maximilian, Sattler, Stefan M, Flethoj, M., Høtbjerg Hansen, M. E., Hesselkilde, E. M., Saljic, Arnela, Wirth, K., Dr Linz, Dominik Karl, Tfelt-Hansen, Jacob & Jespersen, Thomas, 2021, In: Heart Rhythm. 18, 8, p. 1384-1391

      Research output: Contribution to journalJournal articleResearchpeer-review

    76. Published

      Pharmacological inhibition of SK-channels with AP14145 prevents atrial arrhythmogenic changes in a porcine model for obstructive respiratory events

      Linz, Benedikt Maximilian, Hesselkilde, E. M., Skarsfeldt, M. A., Hertel, Julie Norup, Sattler, Stefan M, Yan, Y., Tfelt-Hansen, Jacob, Diness, Jonas Goldin, Bentzen, Bo Hjorth, Dr Linz, Dominik Karl & Jespersen, Thomas, 2023, In: Journal of Cardiovascular Electrophysiology. 34, 1, p. 126-134 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    77. Published

      Pharmacological inhibition of sodium-proton-exchanger subtype 3-mediated sodium absorption in the gut reduces atrial fibrillation susceptibility in obese spontaneously hypertensive rats

      Linz, Benedikt Maximilian, Hohl, M., Mishima, R., Saljic, Arnela, Lau, D. H., Jespersen, Thomas, Schotten, U., Sanders, P. & Dr Linz, Dominik Karl, 2020, In: IJC Heart and Vasculature. 28, 7 p., 100534.

      Research output: Contribution to journalJournal articleResearchpeer-review

    78. Published

      G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

      Liang, B., Nissen, J. D., Laursen, M., Wang, X., Skibsbye, L., Hearing, M. C., Andersen, M. N., Rasmussen, Hanne Borger, Wickman, K., Grunnet, Morten, Olesen, Søren-Peter & Jespersen, Thomas, 1 Jan 2014, In: Cardiovascular Research. 101, 1, p. 175-84 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    79. Published

      Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts

      Laursen, M., Grunnet, Morten, Olesen, Søren-Peter, Jespersen, Thomas & Mow, T., 2012, In: Journal of Pharmacological and Toxicological Methods. 64, 2, p. 134-44 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    80. Published

      Characterization of cardiac repolarization in the Göttingen minipig

      Laursen, M., Olesen, Søren-Peter, Grunnet, Morten, Mow, T., Jespersen, T. & Jespersen, Thomas, 2011, In: Journal of Pharmacological and Toxicological Methods. 63, 2, p. 186-95 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    81. Published

      Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.

      Larsen, A. P., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, 2008, In: Pflügers Archiv: European Journal of Physiology. 456, 6, p. 1137-48 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    82. Published

      Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels

      Krzystanek, K., Rasmussen, Hanne Borger, Grunnet, Morten, Staub, O., Olesen, Søren-Peter, Abriel, H. & Jespersen, Thomas, 2012, In: Heart Rhythm. 9, 3, p. 440-8 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    83. Published

      Necropsy Validation of a Novel Method for Left Ventricular Mass Quantification in Porcine Transthoracic and Transdiaphragmal Echocardiography

      Kristensen, C. B., Sattler, Stefan M, Lubberding, Anniek Frederike, Tfelt-Hansen, Jacob, Jespersen, Thomas, Hassager, Christian & Mogelvang, R., 2022, In: Frontiers in Cardiovascular Medicine. 9, 868603.

      Research output: Contribution to journalJournal articleResearchpeer-review

    84. Published

      Brugada syndrome unmasked by accidental inhalation of gasoline vapors.

      Kranjcec, D., Bergovec, M., Rougier, J., Raguz, M., Pavlovic, S., Jespersen, Thomas, Castella, V., Keller, D. I. & Abriel, H., 2007, In: Pacing and Clinical Electrophysiology. 30, 10, p. 1294-8 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    85. Published

      An ERG channel inhibitor from the scorpion Buthus eupeus

      Korolkova, Y. V., Kozlov, S. A., Lipkin, A. V., Pluzhnikov, K. A., Hadley, J. K., Filippov, A. K., Brown, D. A., Pedersen, K. A., Strøbaek, D., Jespersen, Thomas, Olesen, Søren-Peter, Jensen Skanning, B. & Grishin, E. V., 30 Mar 2001, In: Journal of Biological Chemistry. 276, 13, p. 9868-76 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    86. Published

      Structural and electro-anatomical characterization of the equine pulmonary veins: implications for atrial fibrillation

      Kjeldsen, S. T., Nissen, Sarah Dalgas, Saljic, Arnela, Hesselkilde, E. M., Carstensen, Helena, Sattler, Stefan M, Jespersen, Thomas, Dr Linz, Dominik Karl, Hopster-Iversen, Charlotte, Kutieleh, R., Sanders, P. & Buhl, Rikke, 2024, In: Journal of Veterinary Cardiology. 52, p. 1-13

      Research output: Contribution to journalJournal articleResearchpeer-review

    87. Published

      Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation

      Kirchhoff, J. E., Diness, Jonas Goldin, Abildgaard, L., Sheykhzade, Majid, Grunnet, Morten & Jespersen, Thomas, 8 Oct 2016, In: Pfluegers Archiv. 468, 11, p. 1853–1863 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    88. Published

      The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

      Kirchhoff, J. E., Skarsfeldt, M., Muthukumarasamy, K. M., Simó-Vicens, R., Bomholtz, Sofia Hammami, Abildgaard, L., Jespersen, Thomas, Sørensen, U. S., Grunnet, Morten, Bentzen, Bo Hjorth & Diness, Jonas Goldin, 2019, In: Frontiers in Pharmacology. 10, 13 p., 668.

      Research output: Contribution to journalJournal articleResearchpeer-review

    89. Published

      Synergistic antiarrhythmic effect of combining inhibition of Ca(2+)-activated K(+) (SK) channels and voltage-gated Na(+) channels in an isolated heart model of atrial fibrillation

      Kirchhoff, J. E., Goldin Diness, J., Sheykhzade, Majid, Grunnet, M. & Jespersen, Thomas, Feb 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 2, p. 409-18 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    90. Published

      Flecainide provocation reveals concealed brugada syndrome in a long QT syndrome family with a novel L1786Q mutation in SCN5A. SCN5A mutations associated with overlap phenotype of long QT syndrome type 3 and Brugada syndrome.

      Kanters, Jørgen K., Yuan, L., Hedley, P. L., Stoevring, B., Jons, C., Bloch Thomsen, P. E., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 6 Mar 2014, In: Circulation Journal. 78, 5, p. 1136-43 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    91. Published

      Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family

      Kanters, Jørgen K., Skibsbye, L., Hedley, P. L., Dembic, M., Liang, B., Hagen, C. M., Eschen, O., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 2015, In: Scandinavian Journal of Clinical & Laboratory Investigation. 75, 8, p. 699-709 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    92. Published

      Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization

      Jørgensen, S. T., Eriksen, H. N., Dausell, J., Jespersen, Thomas, Lambert, Ian Henry & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 31, 2-3, p. 366-378 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    93. Published

      Urinary markers of nucleic acid oxidation increase with age, obesity and insulin resistance in Danish children and adolescents

      Jors, A., Lund, M. A. ,. V., Jespersen, Thomas, Hansen, Torben, Poulsen, Henrik Enghusen & Holm, Jens-Christian, 2020, In: Free Radical Biology and Medicine. 155, p. 81-86

      Research output: Contribution to journalJournal articleResearchpeer-review

    94. Published

      Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes

      Jespersen, Thomas, Grunnet, Morten, Angelo, K., Klærke, Dan Arne & Olesen, Poul, 1 Mar 2002, In: BioTechniques. 32, 3, p. 536-8, 540

      Research output: Contribution to journalJournal articleResearchpeer-review

    95. Published

      Regulation and physiological function of Na(v) 1.5 and KCNQ1 channels

      Jespersen, Thomas, 2011, In: Acta Physiologica (Print). 202 Suppl 683, p. 1-26 26 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    96. Published

      Kondo physics in tunable semicondouctor nanowire quantum dots

      Jespersen, Thomas, Aagesen, M., Sørensen, Claus Birger, Lindelof, Poul Erik & Nygård, Jesper, 2006, In: Physical Review B. Condensed Matter and Materials Physics. 74, 23, p. 233304

      Research output: Contribution to journalJournal articleResearchpeer-review

    97. Published

      Cardiac Arrhythmia - new considerations: The Cardiac Ion Channels

      Jespersen, Thomas, 29 Feb 2012, Cardiac Arrhythmias - new considerations. Breijo-Marquez, F. R. (ed.). Croatia: InTech, p. 45-72 29 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    98. Published

      Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif.

      Jespersen, Thomas, Rasmussen, Hanne Borger, Grunnet, Morten, Jensen, H. S., Angelo, K., Dupuis, D. S., Vogel, L. K., Jorgensen, N. K., Klærke, Dan Arne & Olesen, Søren-Peter, 2004, In: Journal of Cell Science. 117, Pt 19, p. 4517-26 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    99. Published

      The KCNQ1 potassium channel: from gene to physiological function.

      Jespersen, Thomas, Grunnet, Morten & Olesen, Søren-Peter, 2005, In: Physiology. 20, p. 408-16 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    100. Published

      Effect of Selective IK,ACh Inhibition by XAF-1407 in an Equine Model of Tachypacing-induced Persistent Atrial Fibrillation (AF)

      Jespersen, Thomas, Fenner, Merle Friederike & Buhl, Rikke, 2019, In: Acta Physiologica. 227, S721, p. 96-96

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    Previous 1 2 Next

    ID: 8117