Thomas Jespersen
Professor
Physiology of circulation, kidney and lung
Blegdamsvej 3, Building: 12-5-08
2200 København N
Denmark
Member of:
- Published
The sodium channel activator Lu AE98134 normalizes the altered firing properties of fast spiking interneurons in Dlx5/6+/- mice
von Schoubye, N. L., Frederiksen, K., Kristiansen, Uffe, Petersen, A. V., Dalby, N. O., Grunnet, M., Jensen, H. S., Jespersen, Thomas, Sohal, V. S. & Perrier, Jean-Francois Marie, 2018, In: Neuroscience Letters. 662, p. 29-35 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynein regulates Kv7.4 channel trafficking from the cell membrane
van der Horst, Jennifer, Rognant, Salomé, Abbott, G. W., Ozhathil, Lijo Cherian, Hägglund, Per Mårten, Barrese, V., Chuang, Christine, Jespersen, Thomas, Davies, Michael J., Greenwood, I. A., Gourdon, Pontus Emanuel, Aalkjær, Christian & Jepps, Thomas Andrew Qvistgaard, 2021, In: Journal of General Physiology. 153, 3, 19 p., e202012760.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacological exploration of the resting membrane potential reserve: Impact on atrial fibrillation
van der Heyden, M. A. G. & Jespersen, Thomas, 15 Jan 2016, In: European Journal of Pharmacology. 771, p. 56-64 9 p.Research output: Contribution to journal › Review › Research › peer-review
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Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada Syndrome mutant
Yuan, L., Koivumaki, J., Liang, B., Lorentzen, L. G., Tang, C., Andersen, M. N., Svendsen, Jesper Hastrup, Tfelt-Hansen, J., Maleckar, M., Schmitt, Nicole, Olesen, Morten Steen Salling & Jespersen, Thomas, 21 Feb 2014, In: American Journal of Physiology: Heart and Circulatory Physiology. 306, 8, p. H1204-12Research output: Contribution to journal › Journal article › Research › peer-review
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Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.
Yuan, L., Koivumäki, J., Liang, B., Lorentzen, Lasse Gøbel, Tang, C., Andersen, M., Svendsen, J., Tfelt-Hansen, Jacob, Maleckar, M., Schmitt, Nicole, Olesen, M. & Jespersen, Thomas, Feb 2014, In: American journal of physiology. Heart and circulatory physiology.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of a Kir3.4 Mutation in Congenital Long QT Syndrome
Yang, Y., Yang, Y., Liang, B., Liu, J., Li, J., Grunnet, M., Olesen, S-P., Rasmussen, H. B., Ellinor, P. T., Gao, L., Lin, X., Li, L., Wang, L., Xiao, J., Liu, Y., Liu, Y., Zhang, S., Liang, D., Peng, L., Jespersen, T. & 1 others, , 2010, In: American Journal of Human Genetics. 86, 6, p. 872-80 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome
Winkel, B. G., Yuan, L., Olesen, Morten Steen Salling, Sadjadieh, G., Wang, Y., Risgaard, B., Jabbari, R., Haunsø, Stig, Holst, A. G., Hollegaard, M. V., Tfelt-Hansen, J. & Jespersen, Thomas, Jun 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 6, p. 1241-1249 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MR-proANP measured at admission is associated with incident atrial fibrillation in STEMI patients
Wegener, A., Modin, D., Pedersen, S., Lindberg, S., Pareek, M., Iversen, Kasper, Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2022, In: Heart and Vessels. 37, p. 1906–1913 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology
Wang, X., Liang, B., Skibsbye, L., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, Aug 2013, In: Journal of Cardiovascular Pharmacology. 62, 2, p. 192-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Population-based pediatric reference values for serum parathyroid hormone, vitamin D, calcium, and phosphate in Danish/North-European white children and adolescents
Vissing Landgrebe, A., Lund, Morten Asp Vonsild, Lausten-Thomsen, U., Frithioff-Bøjsøe, C., Fonvig, Cilius Esmann, Lind Plesner, J., Aas Holm, L., Jespersen, Thomas, Hansen, Torben & Holm, Jens-Christian, 2021, In: Clinica Chimica Acta. 523, p. 483-490Research output: Contribution to journal › Journal article › Research › peer-review
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Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis
Tommiska, J., Känsäkoski, J., Skibsbye, L., Vaaralahti, K., Liu, X., Lodge, E. J., Tang, C., Yuan, L., Fagerholm, R., Kanters, J. K., Lahermo, P., Kaunisto, M., Keski-Filppula, R., Vuoristo, S., Pulli, K., Ebeling, T., Valanne, L., Sankila, E-M., Kivirikko, S., Lääperi, M. & 15 others, , 3 Nov 2017, In: Nature Communications. 8, 1, 11 p., 1289.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiac channelopathies and sudden infant death syndrome
Tfelt-Hansen, J., Winkel, B. G., Grunnet, Morten & Jespersen, Thomas, 2011, In: The Cardiology. 119, 1, p. 21-33 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Arvelige hjertesygdomme forårsaget af natriumkanalmutationer
Tfelt-Hansen, J., Olesen, Søren-Peter, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2009, In: Ugeskrift for læger. 171, 15, p. 1261-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inherited Cardiac Diseases Caused by Mutations in the Nav1.5 Sodium Channel
Tfelt-Hansen, J., Winkel, B. G., Grunnet, Morten & Jespersen, Thomas, 2009, In: Cardiovascular Electrophysiology.Research output: Contribution to journal › Journal article › Research › peer-review
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Inherited cardiac diseases caused by mutations in the Nav1.5 sodium channel.
Tfelt-Hansen, Jacob, Winkel, B., Grunnet, Morten & Jespersen, Thomas, Oct 2009, In: Journal of Cardiovascular Electrophysiology.Research output: Contribution to journal › Journal article › Research › peer-review
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Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A
Tfelt-Hansen, J., Jespersen, Thomas, Hofman-Bang, J., Rasmussen, Hanne Borger, Cedergreen, P., Skovby, F., Abriel, H., Svendsen, Jesper Hastrup, Olesen, S., Christiansen, M. & Haunso, S., 2009, In: Canadian Journal of Cardiology. 25, 3, p. 156-60 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biophysical characterization of KV3.1 potassium channel activating compounds
Taskin, B., von Schoubye, N. L., Sheykhzade, Majid, Bastlund, J. F., Grunnet, M. & Jespersen, Thomas, 5 Jul 2015, In: European Journal of Pharmacology. 758, p. 164-170 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms
Tang, C., Skibsbye, L., Yuan, L., Bentzen, Bo Hjorth & Jespersen, Thomas, Oct 2015, In: General Physiology and Biophysics. 34, 4, p. 383-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cause-specific mortality in children and young adults with diabetes mellitus: A Danish nationwide cohort study
Svane, Jesper, Lynge, T. H., Pedersen-Bjergaard, Ulrik, Jespersen, Thomas, Gislason, Gunnar Hilmar, Risgaard, B., Winkel, B. G. & Tfelt-Hansen, Jacob, 2021, In: European Journal of Preventive Cardiology. 28, 2, p. 159-165Research output: Contribution to journal › Journal article › Research › peer-review
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Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts
Soltysinska, E., Olesen, Søren-Peter, Christ, T., Wettwer, E., Varró, A., Grunnet, Morten & Jespersen, Thomas, 2009, In: Pflügers Archiv: European Journal of Physiology. 459, 1, p. 11-23 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Acetylcholine-Activated Potassium Current Inhibitor XAF-1407 Terminates Persistent Atrial Fibrillation in Goats
Sobota, V., Gatta, G., van Hunnik, A., van Tuijn, I., Kuiper, M., Milnes, J., Jespersen, Thomas, Schotten, U. & Verheule, S., 2021, In: Frontiers in Pharmacology. 11, 13 p., 608410.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of Adenosine Pathway Alters Atrial Electrophysiology and Prevents Atrial Fibrillation
Soattin, Luca, Lubberding, Anniek Frederike, Bentzen, Bo Hjorth, Christ, T. & Jespersen, Thomas, 2020, In: Frontiers in Physiology. 11, 14 p., 493.Research output: Contribution to journal › Journal article › Research › peer-review
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Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium
Skibsbye, L., Wang, X., Axelsen, L. N., Bomholtz, Sofia Hammami, Nielsen, Morten Schak, Grunnet, Morten, Bentzen, Bo Hjorth & Jespersen, Thomas, Aug 2015, In: Journal of Cardiovascular Pharmacology. 66, 2, p. 165-176 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria
Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, 1 Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-67 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During beta-Adrenergic and Muscarinic Receptor Activation
Skibsbye, L., Bengaard, A. K., Uldum-Nielsen, A. M., Boddum, K., Christ, T. & Jespersen, Thomas, 2018, In: Frontiers in Physiology. 9Research output: Contribution to journal › Journal article › Research › peer-review
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Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarisation in human atria.
Skibsbye, L., Poulet, C., Diness, Jonas Goldin, Bentzen, Bo Hjorth, Yuan, L., Kappert, U., Matschke, K., Wettwer, E., Ravens, U., Grunnet, M., Christ, T. & Jespersen, Thomas, Jul 2014, In: Cardiovascular Research. 103, 1, p. 156-167 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Refractoriness in human atria: Time and voltage dependence of sodium channel availability
Skibsbye, L., Jespersen, Thomas, Christ, T., Maleckar, M. M., van den Brink, J., Tavi, P. & Koivumäki, J. T., Dec 2016, In: Journal of Molecular and Cellular Cardiology. 101, p. 26-34 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacological inhibition of I-K1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness
Skarsfeldt, M. A., Carstensen, Helena, Skibsbye, L., Tang, C., Buhl, Rikke, Bentzen, Bo Hjorth & Jespersen, Thomas, Apr 2016, In: Physiological Reports. 4, 8, 11 p., e12734.Research output: Contribution to journal › Journal article › Research › peer-review
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KCNQ4 channel activation by BMS-204352 and retigabine
Schrøder, R. L. K., Jespersen, Thomas, Christophersen, P., Strøbaek, D., Jensen, B. S. & Olesen, Poul, 1 Jun 2001, In: Neuropharmacology. 40, 7, p. 888-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ventricular Arrhythmias in First Acute Myocardial Infarction: Epidemiology, Mechanisms, and Interventions in Large Animal Models
Sattler, S. M., Skibsbye, L., Dr Linz, Dominik Karl, Lubberding, Anniek Frederike, Tfelt-Hansen, Jacob & Jespersen, Thomas, 2019, In: Frontiers in Cardiovascular Medicine. 6, 14 p., 158.Research output: Contribution to journal › Review › Research › peer-review
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Amiodarone Treatment in the Early Phase of Acute Myocardial Infarction Protects Against Ventricular Fibrillation in a Porcine Model
Sattler, Stefan M, Lubberding, Anniek Frederike, Skibsbye, L., Jabbari, R., Wakili, R., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2019, In: Journal of Cardiovascular Translational Research. 12, 4, p. 321-330Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of the antipsychotic drug haloperidol on arrhythmias during acute myocardial infarction in a porcine model
Sattler, Stefan M, Lubberding, Anniek Frederike, Kristensen, C. B., Møgelvang, R., Blanche, Paul Frédéric, Fink-Jensen, Anders, Engstrøm, Thomas, Kääb, S., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2020, In: IJC Heart and Vasculature. 26, 100455.Research output: Contribution to journal › Journal article › Research › peer-review
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The impact of an atrial septal defect on the progression of atrial tachypacing-induced atrial fibrillation in a Danish Landrace pig: A case report
Saljic, Arnela, Hertel, Julie Norup, Leonhardt, C., Nissen, Sarah Dalgas, Dobrev, D., Jepps, Thomas Andrew Qvistgaard, Jespersen, Thomas & Sattler, Stefan M, 2022, In: IJC Heart and Vasculature. 40, 3 p., 101054.Research output: Contribution to journal › Letter › Research › peer-review
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Increased fibroblast accumulation in the equine heart following persistent atrial fibrillation
Saljic, Arnela, Fenner, Merle Friederike, Winters, J., Flethøj, M., Eggert Eggertsen, C., Carstensen, Helena, Nissen, Sarah Dalgas, Melis Hesselkilde, E., van Hunnik, A., Schotten, U., Sørensen, U., Jespersen, Thomas, Verheule, S. & Buhl, Rikke, 2021, In: IJC Heart and Vasculature. 35, 100842.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of arrhythmogenic calmodulin variants on small conductance Ca2+-activated K+ (SK3) channels
Saljic, Arnela, Muthukumarasamy, K. M., la Cour, J. M., Boddum, K., Grunnet, Morten, Berchtold, Martin Werner & Jespersen, Thomas, 2019, In: Physiological Reports. 7, 19, 13 p., e14210.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo knockdown of SK3 channels using antisense oligonucleotides protects against atrial fibrillation in rats
Saljic, Arnela, Soattin, Luca, Trachsel, D. S., Boddum, K. & Jespersen, Thomas, Oct 2020, In: Journal of Molecular and Cellular Cardiology. 147, p. 18-26Research output: Contribution to journal › Journal article › Research › peer-review
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Anti-arrhythmic investigations in large animal models of atrial fibrillation
Saljic, Arnela, Jespersen, Thomas & Buhl, Rikke, 2022, In: British Journal of Pharmacology. 179, 5, p. 838-858Research output: Contribution to journal › Review › Research › peer-review
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Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins.
Rougier, J., van Bemmelen, M. X., Bruce, M. C., Jespersen, Thomas, Gavillet, B., Apothéloz, F., Cordonier, S., Staub, O., Rotin, D. & Abriel, H., 2004, In: American Journal of Physiology: Cell Physiology. 288, 3, p. C692-701Research output: Contribution to journal › Journal article › Research › peer-review
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Change in global longitudinal strain following acute coronary syndrome and subsequent risk of heart failure
Ravnkilde, K., Skaarup, K. G., Grove, G. L., Modin, D., Nielsen, A. B., Falsing, M. M., Iversen, A. Z., Pedersen, S., Fritz-Hansen, T., Galatius, S., Jespersen, Thomas, Shah, A., Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2021, In: International Journal of Cardiovascular Imaging. 37, p. 3193–3202Research output: Contribution to journal › Journal article › Research › peer-review
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Utility of left atrial strain for predicting atrial fibrillation following ischemic stroke
Rasmussen, S. M. A., Olsen, F. J., Jorgensen, P. G., Fritz-Hansen, T., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2019, In: International Journal of Cardiovascular Imaging. 35, 9, p. 1605-1613Research output: Contribution to journal › Journal article › Research › peer-review
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Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation
Poulet, C., Wettwer, E., Grunnet, Morten, Jespersen, Thomas, Fabritz, L., Matschke, K., Knaut, M. & Ravens, U., 29 Jun 2015, In: PLOS ONE. 10, 6, p. 1-19 19 p., e0131432.Research output: Contribution to journal › Journal article › Research › peer-review
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Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome.
Petitprez, S., Jespersen, Thomas, Pruvot, E., Keller, D. I., Corbaz, C., Schläpfer, J., Abriel, H. & Kucera, J. P., 2008, In: Cardiovascular Research. 78, 3, p. 494-504 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Muscarinic Receptor Activation Reduces Force and Arrhythmias in Human Atria Independent of IK,ACh
Petersen, J., Castro, L., Bengaard, A. K. P., Pecha, S., Ismaili, D., Schulz, C., Sahni, J., Steenpass, A., Meier, C., Reichenspurner, H., Jespersen, Thomas, Eschenhagen, T. & Christ, T., 2022, In: Journal of Cardiovascular Pharmacology. 79, 5, p. 678-686Research output: Contribution to journal › Journal article › Research › peer-review
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Subtype-specific, bi-component inhibition of SK channels by low internal pH.
Peitersen, T., Jespersen, Thomas, Jorgensen, N. K., Olesen, Søren-Peter & Grunnet, Morten, 2006, In: Biochemical and Biophysical Research Communications. 343, 3, p. 943-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Clinical Implications of SCN10A Loss-of-Function Variants in 169 610 Exomes Representing the General Population.
Paludan-Müller, Christian, Larsen, S., Ahlberg, G., Monfort, L. M., Andreasen, L., Svendsen, Jesper Hastrup, Jespersen, Thomas, Bundgård, Henning, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2022, In: Circulation. Genomic and precision medicine. 15, 1, p. 83-85 3 p., e003574.Research output: Contribution to journal › Letter › Research › peer-review
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Time matters: characterization of fibroblast-like cells harvested from pig profundus tendon stored at room temperature at different postmortem time intervals
Ozhathil, Lijo Cherian, Chen, Y., Nissen, Sarah Dalgas, Banner, Jytte, Tfelt-Hansen, Jacob & Jespersen, Thomas, 2022, In: In Vitro Cellular and Developmental Biology - Animal. 58, p. 633–637Research output: Contribution to journal › Journal article › Research › peer-review
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Screening of KCNN3 in patients with early-onset lone atrial fibrillation
Olesen, M. S., Jabbari, J., Holst, A. G., Nielsen, J. B., Steinbrüchel, D. A., Jespersen, T., Haunsø, Stig, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2011, In: Europace. 13, 7, p. 963-967 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutations in sodium channel {beta}-subunit SCN3B are associated with early-onset lone atrial fibrillation
Olesen, M. S., Jespersen, Thomas, Nielsen, J. B., Liang, B., Møller, D. V., Hedley, P., Christiansen, M., Varro, A., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole & Svendsen, Jesper Hastrup, 2011, In: Cardiovascular Research. 89, 4, p. 786-793 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High Prevalence of Long QT Syndrome Associated SCN5A Variants in Patients with Early-Onset Lone Atrial Fibrillation
Olesen, M. S., Yuan, L., Liang, B., Holst, A. G., Nielsen, N., Nielsen, J. B., Hedley, P. L., Christiansen, M., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole, Jespersen, Thomas & Svendsen, Jesper Hastrup, 2012, In: Circulation: Cardiovascular Genetics. 5, 4, p. 450-459 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Novel Nonsense Variant in Nav1.5 Cofactor MOG1 Eliminates Its Sodium Current Increasing Effect and May Increase the Risk of Arrhythmias
Olesen, M. S., Jensen, N. F., Holst, A. G., Nielsen, J. B., Tfelt-Hansen, Jacob, Jespersen, Thomas, Sajadieh, Ahmad, Haunsø, Stig, Lund, J. T., Callø, Kirstine, Schmitt, Nicole & Svendsen, Jesper Hastrup, 26 May 2011, In: Canadian Journal of Cardiology. 27, 4, p. 523.e17-23Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of the acetylcholine-regulated potassium current prevents transient apnea-related atrial arrhythmogenic changes in a porcine model
Hertel, Julie Norup, Linz, Benedikt Maximilian, Isaksen, Jonas L., Jerltorp, Kezia, Leonhardt, C., Gottlieb, Lisa Amalie, Saljic, Arnela, Jespersen, Thomas & Dr Linz, Dominik Karl, 2024, In: Heart Rhythm. 21, 5, p. 622-629Research output: Contribution to journal › Journal article › Research › peer-review
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Cartilaginous Intrusion of the Atrioventricular Node in a Quarter Horse with a High Burden of Second-Degree AV Block and Collapse: A Case Report
Nissen, Sarah Dalgas, Saljic, Arnela, Kjeldsen, S. T., Jespersen, Thomas, Hopster-Iversen, Charlotte & Buhl, Rikke, 2022, In: Animals. 12, 21, 2915.Research output: Contribution to journal › Journal article › Research › peer-review
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Muscarinic acetylcholine receptors M2 are upregulated in the atrioventricular nodal tract in horses with a high burden of second-degree atrioventricular block
Nissen, Sarah Dalgas, Saljic, Arnela, Carstensen, Helena, Braunstein, T. H., Hesselkilde, E. M., Kjeldsen, S. T., Hopster-Iversen, Charlotte, D’Souza, A., Jespersen, Thomas & Buhl, Rikke, 2023, In: Frontiers in Cardiovascular Medicine. 10, 10 p., 1102164.Research output: Contribution to journal › Journal article › Research › peer-review
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Electrocardiographic characteristics of trained and untrained standardbred racehorses
Nissen, Sarah Dalgas, Weis, R., Krag-Andersen, E. K., Hesselkilde, E. M., Isaksen, Jonas L., Carstensen, Helena, Kanters, Jørgen K., Dr Linz, Dominik Karl, Sanders, P., Hopster-Iversen, Charlotte, Jespersen, Thomas, Pehrson, S. & Buhl, Rikke, 2022, In: Journal of Veterinary Internal Medicine. 36, 3, p. 1119-1130Research output: Contribution to journal › Journal article › Research › peer-review
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Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure
Nissen, J. D., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Diness, Jonas Goldin, Diness, T. G., Jespersen, Thomas & Grunnet, Morten, 2012, In: Journal of Cardiovascular Pharmacology. 59, 2, p. 142-150 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacologically induced long QT type 2 can be rescued by activation of IKs with benzodiazepine R-L3 in isolated guinea pig cardiomyocytes
Nissen, J. D., Diness, Jonas Goldin, Diness, T. G., Hansen, R. S., Grunnet, Morten & Jespersen, Thomas, 2009, In: Journal of Cardiovascular Pharmacology. 54, 2, p. 169-77 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacological rescue of mutated K(v)3.1 ion-channel linked to progressive myoclonus epilepsies
Munch, A. S., Saljic, Arnela, Boddum, K., Grunnet, Morten, Hougaard, C. & Jespersen, Thomas, 2018, In: European Journal of Pharmacology. 833, p. 255-262Research output: Contribution to journal › Journal article › Research › peer-review
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Intrinsic Electrical Remodeling Underlies Atrioventricular Block in Athletes
Mesirca, P., Nakao, S., Nissen, S. D., Forte, G., Anderson, C., Trussell, T., Li, J., Cox, C., Zi, M., Logantha, S., Yaar, S., Cartensen, H., Bidaud, I., Stuart, L., Soattin, L., Morris, G. M., Da Costa Martins, P. A., Cartwright, E. J., Oceandy, D., Mangoni, M. E. & 5 others, , 2021, In: Circulation Research. 129, 1, p. E1-E20Research output: Contribution to journal › Journal article › Research › peer-review
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From CMR Image to Patient-Specific Simulation and Population-Based Analysis: Tutorial for an Openly Available Image-Processing Pipeline
Marciniak, M., Arevalo, H., Tfelt-Hansen, Jacob, Jespersen, Thomas, Jabbari, R., Glinge, C., Ahtarovski, K. A., Vejlstrup, N., Engstrøm, Thomas, Maleckar, M. M. & McLeod, K., 1 Jan 2017, Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges - 7th International Workshop, STACOM 2016 Held in Conjunction with MICCAI 2016, Revised Selected Papers. Springer, p. 106-117 12 p. (Lecture Notes in Computer Science, Vol. 10124 LNCS).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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A Multiple Kernel Learning Framework to Investigate the Relationship Between Ventricular Fibrillation and First Myocardial Infarction
Marciniak, M., Arevalo, H., Tfelt-Hansen, Jacob, Ahtarovski, K. A., Jespersen, Thomas, Jabbari, R., Glinge, C., Vejlstrup, N., Engstrøm, Thomas, Maleckar, M. M. & McLeod, K., 1 Jan 2017, Functional Imaging and Modelling of the Heart: 9th International Conference, FIMH 2017, Toronto, ON, Canada, June 11-13, 2017, Proceedings. Springer, p. 161-171 11 p. (Lecture Notes in Computer Science, Vol. 10263 LNCS).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
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Combined In-silico and Machine Learning Approaches Toward Predicting Arrhythmic Risk in Post-infarction Patients
Maleckar, M. M., Myklebust, L., Uv, J., Florvaag, P. M., Strøm, V., Glinge, C., Jabbari, R., Vejlstrup, N., Engstrøm, Thomas, Ahtarovski, K., Jespersen, Thomas, Tfelt-Hansen, Jacob, Naumova, V. & Arevalo, H., 2021, In: Frontiers in Physiology. 12, 745349.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nationwide Burden of Sudden Cardiac Death: A Study of 54,028 Deaths in Denmark
Lynge, T. H., Risgaard, B., Banner, Jytte, Nielsen, J. L., Jespersen, Thomas, Stampe, N. K., Albert, C. M., Winkel, B. G. & Tfelt-Hansen, Jacob, 2021, In: Heart Rhythm. 18, 10, p. 1657-1665Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kredsløbet ændres ved overvægt i barndommen
Lund, Morten Asp Vonsild, Holm, Jens-Christian, Jespersen, Thomas & von Holstein-Rathlou, Niels-Henrik, 2017, In: Ugeskrift for Laeger. 2018, 6, p. 2-6 5 p., V03170265.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Glucagon-like peptide-1 increases heart rate by a direct action on the sinus node
Lubberding, A. F., Veedfald, S., Achter, J. S., Nissen, S. D., Soattin, L., Sorrentino, A., Torres Vega, E., Linz, B., Eggertsen, C. H. E., Mulvey, J., Toräng, S., Larsen, S. A., Nissen, A., Petersen, L. G., Erbil Bilir, S., Bentzen, B. H., Rosenkilde, M. M., Hartmann, B., Lilleør, T. N. B., Qazi, S. & 6 others, , 2024, (E-pub ahead of print) In: Cardiovascular Research. 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of hemodynamics, cardiac electrophysiology and ventricular arrhythmia in an open and a closed chest porcine model of acute myocardial infarction
Lubberding, Anniek Frederike, Sattler, Stefan M, Flethøj, M., Tfelt-Hansen, Jacob & Jespersen, Thomas, 2020, In: American Journal of Physiology: Heart and Circulatory Physiology. 318, 2, p. H391-H400Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V
Lubberding, Anniek Frederike, Zhang, J., Lundh, M., Nielsen, Thomas Svava, Søndergaard, M. S., Villadsen, M., Skovhøj, E. Z., Boer, G. A., Hansen, J. B., Thomsen, Morten Bækgaard, Treebak, Jonas Thue, Holst, Jens Juul, Kanters, Jørgen K., Mandrup-Poulsen, Thomas, Jespersen, Thomas, Emanuelli, Brice & Torekov, Signe Sørensen, 2021, In: Scientific Reports. 11, 1, 14 p., 12253.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Arrhythmia development during inhibition of small-conductance calcium-activated potassium channels in acute myocardial infarction in a porcine model
Lubberding, Anniek Frederike, Sattler, Stefan M, Grunnet, Morten, Sørensen, U. S., Tfelt-Hansen, Jacob & Jespersen, Thomas, Oct 2019, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 21, 10, p. 1584–1593Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pulmonary vein firing initiating atrial fibrillation in the horse: Oversized dimensions but similar mechanisms
Dr Linz, Dominik Karl, Hesselkilde, E., Kutieleh, R., Jespersen, Thomas, Buhl, Rikke & Sanders, P., 2020, In: Journal of Cardiovascular Electrophysiology. 31, 5, p. 1211-1212Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Personalized management of sleep apnea in patients with atrial fibrillation: An interdisciplinary and translational challenge
Dr Linz, Dominik Karl, Linz, Benedikt Maximilian, Dobrev, D., Baumert, M., Hendriks, J. M., Pepin, J. L. & Jespersen, Thomas, 2021, In: IJC Heart and Vasculature. 35, 100843.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Pharmacological inhibition of acetylcholine-regulated potassium current (IK,ACh) prevents atrial arrhythmogenic changes in a rat model of repetitive obstructive respiratory events
Linz, Benedikt Maximilian, Thostrup, A. H., Saljic, Arnela, Rombouts, K., Hertel, Julie Norup, Hohl, M., Milnes, J., Tfelt-Hansen, Jacob, Dr Linz, Dominik Karl & Jespersen, Thomas, Feb 2022, In: Heart Rhythm O2. 3, 1, p. 97-104Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms and Therapeutic Opportunities in Atrial Fibrillation in Relationship to Alcohol Use and Abuse
Linz, Benedikt Maximilian, Hertel, Julie Norup, Jespersen, Thomas & Dr Linz, Dominik Karl, 2022, In: Canadian Journal of Cardiology. 38, 9, p. 1352-1363Research output: Contribution to journal › Review › Research › peer-review
- Published
Repeated exposure to transient obstructive sleep apnea–related conditions causes an atrial fibrillation substrate in a chronic rat model
Linz, Benedikt Maximilian, Hohl, M., Lang, L., Wong, D. W. L., Nickel, A. G., De La Torre, C., Sticht, C., Wirth, K., Boor, P., Maack, C., Speer, T., Jespersen, Thomas, Schotten, U., Sanders, P., Böhm, M. & Dr Linz, Dominik Karl, 2021, In: Heart Rhythm. 18, 3, p. 455-464Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sleep apnea and atrial fibrillation: challenges in clinical and translational research
Linz, Benedikt Maximilian, Hertel, Julie Norup, Hendriks, J., Saljic, Arnela, Dobrev, D., Baumert, M., Jespersen, Thomas & Dr Linz, Dominik Karl, 2022, In: Expert Review of Cardiovascular Therapy. 20, 2, p. 101-109Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of sodium-proton-exchanger subtype 3-mediated sodium absorption in the gut: A new antihypertensive concept
Linz, Benedikt Maximilian, Saljic, Arnela, Hohl, M., Gawalko, M., Jespersen, Thomas, Sanders, P., Bohm, M. & Dr Linz, Dominik Karl, 2020, In: IJC Heart and Vasculature. 29, 7 p., 100591.Research output: Contribution to journal › Review › Research › peer-review
- Published
Arrhythmogenic mechanisms of acute obstructive respiratory events in a porcine model of drug-induced Long-QT
Linz, Benedikt Maximilian, Sattler, Stefan M, Flethoj, M., Høtbjerg Hansen, M. E., Hesselkilde, E. M., Saljic, Arnela, Wirth, K., Dr Linz, Dominik Karl, Tfelt-Hansen, Jacob & Jespersen, Thomas, 2021, In: Heart Rhythm. 18, 8, p. 1384-1391Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological inhibition of SK-channels with AP14145 prevents atrial arrhythmogenic changes in a porcine model for obstructive respiratory events
Linz, Benedikt Maximilian, Hesselkilde, E. M., Skarsfeldt, M. A., Hertel, Julie Norup, Sattler, Stefan M, Yan, Y., Tfelt-Hansen, Jacob, Diness, Jonas Goldin, Bentzen, Bo Hjorth, Dr Linz, Dominik Karl & Jespersen, Thomas, 2023, In: Journal of Cardiovascular Electrophysiology. 34, 1, p. 126-134 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacological inhibition of sodium-proton-exchanger subtype 3-mediated sodium absorption in the gut reduces atrial fibrillation susceptibility in obese spontaneously hypertensive rats
Linz, Benedikt Maximilian, Hohl, M., Mishima, R., Saljic, Arnela, Lau, D. H., Jespersen, Thomas, Schotten, U., Sanders, P. & Dr Linz, Dominik Karl, 2020, In: IJC Heart and Vasculature. 28, 7 p., 100534.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization
Liang, B., Nissen, J. D., Laursen, M., Wang, X., Skibsbye, L., Hearing, M. C., Andersen, M. N., Rasmussen, Hanne Borger, Wickman, K., Grunnet, Morten, Olesen, Søren-Peter & Jespersen, Thomas, 1 Jan 2014, In: Cardiovascular Research. 101, 1, p. 175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts
Laursen, M., Grunnet, Morten, Olesen, Søren-Peter, Jespersen, Thomas & Mow, T., 2012, In: Journal of Pharmacological and Toxicological Methods. 64, 2, p. 134-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of cardiac repolarization in the Göttingen minipig
Laursen, M., Olesen, Søren-Peter, Grunnet, Morten, Mow, T., Jespersen, T. & Jespersen, Thomas, 2011, In: Journal of Pharmacological and Toxicological Methods. 63, 2, p. 186-95 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.
Larsen, A. P., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, 2008, In: Pflügers Archiv: European Journal of Physiology. 456, 6, p. 1137-48 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels
Krzystanek, K., Rasmussen, Hanne Borger, Grunnet, Morten, Staub, O., Olesen, Søren-Peter, Abriel, H. & Jespersen, Thomas, 2012, In: Heart Rhythm. 9, 3, p. 440-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Necropsy Validation of a Novel Method for Left Ventricular Mass Quantification in Porcine Transthoracic and Transdiaphragmal Echocardiography
Kristensen, C. B., Sattler, Stefan M, Lubberding, Anniek Frederike, Tfelt-Hansen, Jacob, Jespersen, Thomas, Hassager, Christian & Mogelvang, R., 2022, In: Frontiers in Cardiovascular Medicine. 9, 868603.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brugada syndrome unmasked by accidental inhalation of gasoline vapors.
Kranjcec, D., Bergovec, M., Rougier, J., Raguz, M., Pavlovic, S., Jespersen, Thomas, Castella, V., Keller, D. I. & Abriel, H., 2007, In: Pacing and Clinical Electrophysiology. 30, 10, p. 1294-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An ERG channel inhibitor from the scorpion Buthus eupeus
Korolkova, Y. V., Kozlov, S. A., Lipkin, A. V., Pluzhnikov, K. A., Hadley, J. K., Filippov, A. K., Brown, D. A., Pedersen, K. A., Strøbaek, D., Jespersen, Thomas, Olesen, Søren-Peter, Jensen Skanning, B. & Grishin, E. V., 30 Mar 2001, In: Journal of Biological Chemistry. 276, 13, p. 9868-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural and electro-anatomical characterization of the equine pulmonary veins: implications for atrial fibrillation
Kjeldsen, S. T., Nissen, Sarah Dalgas, Saljic, Arnela, Hesselkilde, E. M., Carstensen, Helena, Sattler, Stefan M, Jespersen, Thomas, Dr Linz, Dominik Karl, Hopster-Iversen, Charlotte, Kutieleh, R., Sanders, P. & Buhl, Rikke, 2024, In: Journal of Veterinary Cardiology. 52, p. 1-13Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation
Kirchhoff, J. E., Diness, Jonas Goldin, Abildgaard, L., Sheykhzade, Majid, Grunnet, Morten & Jespersen, Thomas, 8 Oct 2016, In: Pfluegers Archiv. 468, 11, p. 1853–1863 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts
Kirchhoff, J. E., Skarsfeldt, M., Muthukumarasamy, K. M., Simó-Vicens, R., Bomholtz, Sofia Hammami, Abildgaard, L., Jespersen, Thomas, Sørensen, U. S., Grunnet, Morten, Bentzen, Bo Hjorth & Diness, Jonas Goldin, 2019, In: Frontiers in Pharmacology. 10, 13 p., 668.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synergistic antiarrhythmic effect of combining inhibition of Ca(2+)-activated K(+) (SK) channels and voltage-gated Na(+) channels in an isolated heart model of atrial fibrillation
Kirchhoff, J. E., Goldin Diness, J., Sheykhzade, Majid, Grunnet, M. & Jespersen, Thomas, Feb 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 2, p. 409-18 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Flecainide provocation reveals concealed brugada syndrome in a long QT syndrome family with a novel L1786Q mutation in SCN5A. SCN5A mutations associated with overlap phenotype of long QT syndrome type 3 and Brugada syndrome.
Kanters, Jørgen K., Yuan, L., Hedley, P. L., Stoevring, B., Jons, C., Bloch Thomsen, P. E., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 6 Mar 2014, In: Circulation Journal. 78, 5, p. 1136-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family
Kanters, Jørgen K., Skibsbye, L., Hedley, P. L., Dembic, M., Liang, B., Hagen, C. M., Eschen, O., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 2015, In: Scandinavian Journal of Clinical & Laboratory Investigation. 75, 8, p. 699-709 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization
Jørgensen, S. T., Eriksen, H. N., Dausell, J., Jespersen, Thomas, Lambert, Ian Henry & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 31, 2-3, p. 366-378 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urinary markers of nucleic acid oxidation increase with age, obesity and insulin resistance in Danish children and adolescents
Jors, A., Lund, M. A. ,. V., Jespersen, Thomas, Hansen, Torben, Poulsen, Henrik Enghusen & Holm, Jens-Christian, 2020, In: Free Radical Biology and Medicine. 155, p. 81-86Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes
Jespersen, Thomas, Grunnet, Morten, Angelo, K., Klærke, Dan Arne & Olesen, Poul, 1 Mar 2002, In: BioTechniques. 32, 3, p. 536-8, 540Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation and physiological function of Na(v) 1.5 and KCNQ1 channels
Jespersen, Thomas, 2011, In: Acta Physiologica (Print). 202 Suppl 683, p. 1-26 26 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kondo physics in tunable semicondouctor nanowire quantum dots
Jespersen, Thomas, Aagesen, M., Sørensen, Claus Birger, Lindelof, Poul Erik & Nygård, Jesper, 2006, In: Physical Review B. Condensed Matter and Materials Physics. 74, 23, p. 233304Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiac Arrhythmia - new considerations: The Cardiac Ion Channels
Jespersen, Thomas, 29 Feb 2012, Cardiac Arrhythmias - new considerations. Breijo-Marquez, F. R. (ed.). Croatia: InTech, p. 45-72 29 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif.
Jespersen, Thomas, Rasmussen, Hanne Borger, Grunnet, Morten, Jensen, H. S., Angelo, K., Dupuis, D. S., Vogel, L. K., Jorgensen, N. K., Klærke, Dan Arne & Olesen, Søren-Peter, 2004, In: Journal of Cell Science. 117, Pt 19, p. 4517-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The KCNQ1 potassium channel: from gene to physiological function.
Jespersen, Thomas, Grunnet, Morten & Olesen, Søren-Peter, 2005, In: Physiology. 20, p. 408-16 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Selective IK,ACh Inhibition by XAF-1407 in an Equine Model of Tachypacing-induced Persistent Atrial Fibrillation (AF)
Jespersen, Thomas, Fenner, Merle Friederike & Buhl, Rikke, 2019, In: Acta Physiologica. 227, S721, p. 96-96Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
ID: 8117
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Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses
Research output: Contribution to journal › Journal article › Research › peer-review
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355
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Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs
Research output: Contribution to journal › Journal article › Research › peer-review
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333
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Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia
Research output: Contribution to journal › Journal article › Research › peer-review
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