Gustavsson Group – GPCR structure, dynamics and function

We aim to elucidate the molecular details of G protein-coupled receptor (GPCR) receptor function and regulation and translate our findings to biological function and the development of new therapies.





G protein-coupled receptors (GPCRs) relay signals from the outside to the inside of the cell by coupling to G proteins and other intracellular mediators. GPCRs are the targets of around 30% of approved drugs and development of new and therapies is a major focus of academic groups and companies worldwide. In the Gustavsson group, we aim to understand the molecular details of receptor function and regulation and translate our findings to receptor physiology.

We combine characterization of receptor pharmacology in cells and reconstituted systems with characterization of receptor structure and dynamics.



  • Protein expression and purification in prokaryotic and eukaryotic systems
  • Functional characterization by binding and signaling assays (BRET, FRET, radioligand binding, SPR etc) in cells and reconstituted systems
  • Receptor structure and dynamics (cryo-EM, NMR, FRET etc.)
Martin gustavsson

Group Leader

Martin Gustavsson
Associate Professor

ORCID: 0000-0002-3015-2043

Group members

Name Title Phone E-mail
Fabian Nico Pfersdorf Research Assistant   E-mail
Fernando Salgado Polo Postdoc +4535328925 E-mail
Rajesh Regmi Laboratory Technician +4535322006 E-mail
Stefanie Alexandra Eberle Research Assistant +4535335040 E-mail