Nielsen Group - Gap Junction

The research focus of the Gap Junction Group is the regulation of cardiac conduction. We are particularly interested in the role of gap junctions and their use as anti-arrhytmic target.















The work of the Gap Junction Group has contributed to the demonstration that the drug candidate rotigaptide enhanced gap junctional coupling, prevented conduction slowing, reduced rather than increased infarct size and that rotigaptide acted by preventing Cx43 de-phosphorylation.

In later years, the Gap Junction Group has worked on how obesity and pre-diabetes affects cardiac conduction. Metabolic syndrome and diabetic states are associated with arrhythmias and sudden death but underlying causes are still debated.

The group's focus has been on the involvement of conduction disturbances and we have demonstrated that diabetic and pre-diabetic rats have slowed conduction. 














Group Leader Morten Schak Nielsen

Group Leader

Morten Schak Nielsen 
Associate Professor

Phone +45 3532 7427

ORCID: 0000-0002-9718-5421

Group/project members

Internal researchers

Name Title Phone E-mail
Kristoffer Racz Laboratory Technician +4535330725 E-mail