Thorkil Ploug

Thorkil Ploug

Associate Professor

Member of:


    1. 2004
    2. Published

      Contractions induce phosphorylation of the AMPK site Ser565 in hormone-sensitive lipase in muscle.

      Donsmark, M., Langfort, J., Holm, C., Ploug, Thorkil & Galbo, Henrik, 2004, In: Biochemical and Biophysical Research Communications. 316, 3, p. 867-71 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Regulation and role of hormone-sensitive lipase in rat skeletal muscle.

      Donsmark, M., Langfort, J., Holm, C., Ploug, Thorkil & Galbo, Henrik, 2004, In: Proceedings of the Nutrition Society. 63, 2, p. 309-14 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. 2005
    5. Published

      Effect of intermittent fasting and refeeding on insulin action in healthy men.

      Halberg, N., Henriksen, M., Söderhamn, N., Stallknecht, Bente Merete, Ploug, Thorkil, Schjerling, Peter & Dela, Flemming, 2005, In: Journal of Applied Physiology. 99, 6, p. 2128-36 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Expression profiling reveals differences in metabolic gene expression between exercise-induced cardiac effects and maladaptive cardiac hypertrophy.

      Strøm, C. C., Aplin, M., Ploug, Thorkil, Christoffersen, T. E. H., Langfort, J., Viese, M., Galbo, Henrik, Haunsø, Stig & Sheikh, S. P., 2005, In: FEBS Journal. 272, 11, p. 2684-95 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Glucose clearance is higher in arm than leg muscle in type 2 diabetes.

      Olsen, D. B., Sacchetti, M., Dela, Flemming, Ploug, Thorkil & Saltin, B., 2005, In: Journal of Physiology. 565, Pt 2, p. 555-62 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Hormone-sensitive lipase as mediator of lipolysis in contracting skeletal muscle.

      Donsmark, M., Langfort, J., Holm, C., Ploug, Thorkil & Galbo, Henrik, 2005, In: Exercise and Sport Sciences Reviews. 33, 3, p. 127-33 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      Phosphorylation-dependent translocation of glycogen synthase to a novel structure during glycogen resynthesis.

      Prats Gavalda, Clara, Cadefau, J. A., Cussó, R., Qvortrup, Klaus, Nielsen, J. N., Wojtaszewski, J., Hardie, D. G., Stewart, G., Hansen, B. F. & Ploug, Thorkil, 2005, In: Journal of Biological Chemistry. 280, 24, p. 23165-72 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Prevention of hyperglycemia in Zucker diabetic fatty rats by exercise training: effects on gene expression in insulin-sensitive tissues determined by high-density oligonucleotide microarray analysis.

      Colombo, M., Gregersen, S., Kruhoeffer, M., Agger, A., Xiao, J., Jeppesen, P. B., Orntoft, T., Ploug, Thorkil, Galbo, Henrik & Hermansen, K., 2005, In: Metabolism - Clinical and Experimental. 54, 12, p. 1571-81 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Erratum: Phosphorylation-dependent translocation of glycogen synthase to a novel structure during glycogen resynthesis (Journal of Biological Chemistry (2005) 280 (23165-23172))

      Prats, C., Cadefau, J. A., Cussó, R., Qvortrup, Klaus, Nielsen, J. N., Wojtaszewski, Jørgen F P, Hardie, O. G., Stewart, G., Hansen, B. F. & Ploug, Thorkil, 21 Oct 2005, In: Journal of Biological Chemistry. 280, 42, p. 35784 1 p.

      Research output: Contribution to journalComment/debateResearchpeer-review

    12. 2006
    13. Published

      Blood vessels and desmin control the positioning of nuclei in skeletal muscle fibers

      Ralston, E., Lu, Z., Biscocho, N., Soumaka, E., Mavroidis, M., Prats Gavalda, Clara, Lømo, T., Capetanaki, Y. & Ploug, Thorkil, 2006, In: Journal of Cellular Physiology. 209, 3, p. 874-882 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Counterpoint: Glucose phosphorylation is not a significant barrier to glucose uptake by the working muscle.

      Ploug, Thorkil & Vinten, J., 2006, In: Journal of Applied Physiology. 101, 6, p. 1805-6; discussion 1806-8

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Decrease in intramuscular lipid droplets and translocation of HSL in response to muscle contraction and epinephrine.

      Prats Gavalda, Clara, Donsmark, M., Qvortrup, Klaus, Londos, C., Sztalryd, C., Holm, C., Galbo, Henrik & Ploug, Thorkil, 2006, In: Journal of Lipid Research. 47, 11, p. 2392-9 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Early and rapid development of insulin resistance, islet dysfunction and glucose intolerance after high-fat feeding in mice overexpressing phosphodiesterase 3B.

      Walz, H. A., Härndahl, L., Wierup, N., Zmuda-Trzebiatowska, E., Svennelid, F., Manganiello, V. C., Ploug, Thorkil, Sundler, F., Degerman, E., Ahrén, B. & Holst, L. S., 2006, In: Journal of Endocrinology. 189, 3, p. 629-41 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Imaging of insulin signaling in skeletal muscle of living mice shows major role of T-tubules.

      Lauritzen, H. P. M. M., Ploug, Thorkil, Prats Gavalda, Clara, Tavaré, J. M. & Galbo, Henrik, 2006, In: Diabetes. 55, 5, p. 1300-6 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Last Word: Point : Counterpoint author responds to commentaries on "Glucose phosphorylation is/is not a significant barrier to muscle glucose uptake by the working muscle"

      Ploug, Thorkil & Vinten, J., 2006, In: Journal of Applied Physiology. 101, 6, p. 1811-1811

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Point: Counterpoint Glucose Phosphorylation is/ is not a Significant Barrier to Muscle Glucose Uptake By the Working Muscle.

      Wasserman, D. H., Fueger, P., Ploug, Thorkil & Vinten, J., 2006, In: Journal of Applied Physiology.

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. 2007
    21. Published

      Large GLUT4 vesicles are stationary while locally and reversibly depleted during transient insulin stimulation of skeletal muscle of living mice: imaging analysis of GLUT4-enhanced green fluorescent protein vesicle dynamics.

      Lauritzen, H. P. M. M., Galbo, Henrik, Brandauer, J., Goodyear, L. J. & Ploug, Thorkil, 2007, In: Diabetes. 57, 2, p. 315-24 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. 2008
    23. Published

      Denervation and high-fat diet reduce insulin signaling in T-tubules in skeletal muscle of living mice

      Lauritzen, H. P. M. M., Ploug, Thorkil, Ai, H., Donsmark, M., Prats Gavalda, Clara & Galbo, Henrik, 2008, In: Diabetes. 57, 1, p. 13-23 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Large GLUT4 vesicles are stationary while locally and reversibly depleted during transient insulin stimulation of skeletal muscle of living mice - Imaging analysis of GLUT4-enhanced green fluorescent protein vesicle dynamics

      Lauritzen, H. P. M. M., Galbo, Henrik, Brandauer, J., Goodyear, L. J. & Ploug, Thorkil, 2008, In: Diabetes. 57, 2, p. 315-324 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Denervation and high-fat diet reduce insulin signaling in T-tubules in skeletal muscle of living mice

      Lauritzen, H. P. M., Ploug, Thorkil, Ai, H., Donsmark, M., Prats Gavalda, Clara & Galbo, Henrik, Jan 2008, In: Diabetes. 57, 1, p. 13-23 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. 2009
    27. Published

      Cardiac expression of microsomal triglyceride transfer protein is increased in obesity and serves to attenuate cardiac triglyceride accumulation

      Bartels, Emil Daniel, Nielsen, J. M., Hellgren, L. I., Ploug, Thorkil & Nielsen, L. B., 2009, In: PLoS ONE. 4, 4, p. e5300

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      Diet-induced weight loss and exercise alone and in combination enhance the expression of adiponectin receptors in adipose tissue and skeletal muscle, but only diet-induced weight loss enhanced circulating adiponectin

      Christiansen, T., Paulsen, S. K., Bruun, J. M., Ploug, Thorkil, Pedersen, S. B. & Richelsen, B., 2009, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 911-9 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Dual regulation of muscle glycogen synthase during exercise by activation and compartmentalization

      Prats Gavalda, Clara, Helge, Jørn Wulff, Nordby, P., Qvortrup, Klaus, Ploug, Thorkil, Dela, Flemming & Wojtaszewski, Jørgen F P, 2009, In: Journal of Biological Chemistry. 284, 23, p. 15692-15700 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Excitatory amino acid transporters EAAT-1 and EAAT-2 in temporal lobe and hippocampus in intractable temporal lobe epilepsy

      Sarac, S., Afzal, Shoaib, Broholm, H., Madsen, F. F., Ploug, Thorkil & Laursen, H., 2009, In: A P M I S. Acta Pathologica, Microbiologica et Immunologica Scandinavica. 117, 4, p. 291-301 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. 2010
    32. Published

      Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation

      Axelsen, L. N., Lademann, J. B., Petersen, J. S., von Holstein-Rathlou, Niels-Henrik, Ploug, Thorkil, Prats Gavalda, Clara, Pedersen, H. D. & Kjølbye, A. L., 2010, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 298, 6, p. R1560-70

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published

      Dissociation between skeletal muscle inhibitor-{kappa}B kinase/nuclear factor-{kappa}B pathway activity and insulin sensitivity in nondiabetic twins

      Friedrichsen, M., Ribel-Madsen, R., Wojtaszewski, Jørgen F P, Grunnet, Louise Groth, Richter, Erik A., Billestrup, Nils, Ploug, Thorkil, Vaag, A. & Poulsen, P., 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 1, p. 414-421 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Published

      Muscle ceramide content in man is higher in type I than type II fibers and not influenced by glycogen content

      Nordby, P., Prats Gavalda, Clara, Kristensen, D., Ekroos, K., Forsberg, G., Andersen, J. L., Ploug, Thorkil, Dela, Flemming, Storlien, L. & Helge, Jørn Wulff, 2010, In: Journal of Applied Physiology. 109, 5, p. 935-943 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Published

      Opposite effects of pioglitazone and rosiglitazone on mitochondrial respiration in skeletal muscle of patients with type 2 diabetes

      Rabøl, R., Boushel, R., Almdal, Thomas Peter, Hansen, C. N., Ploug, Thorkil, Haugaard, Steen Bendix, Prats Gavalda, Clara, Madsbad, Sten & Dela, Flemming, 2010, In: Diabetes, Obesity and Metabolism Online. 12, 9, p. 806-814 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. 2012
    37. Published

      Body fat loss and compensatory mechanisms in response to different doses of aerobic exercise - a randomized controlled trial in overweight sedentary males

      Larsen, M. R., Auerbach, P. L., Reichkendler, M. H., Ploug, Thorkil, Stallknecht, Bente Merete & Sjödin, Anders Mikael, 2012, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 303, 6, p. R571-R579 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Effect of different doses of exercise on sleep duration, sleep efficiency and sleep quality in sedentary, overweight men

      Quist, Jonas Salling, Rosenkilde, M., Nielsen, S. W., Reichkendler, M. H., Auerbach, P. L., Ploug, Thorkil, Stallknecht, Bente Merete, Sjödin, Anders Mikael & Chaput, J., 2012, In: Bioenergetics. S1, 002, p. 1-6 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Endurance training per se increases metabolic health in young, moderately overweight men

      Nordby, P., Auerbach, P. L., Rosenkilde, M., Kristiansen, L., Thomasen, J. R., Rygaard, L., Groth, R., Brandt, N., Helge, Jørn Wulff, Richter, Erik A., Ploug, Thorkil & Stallknecht, Bente Merete, 2012, In: Obesity. 20, 11, p. 2202-2212 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Purinergic receptors expressed in human skeletal muscle fibres

      Bornø, A., Ploug, Thorkil, Bune, L. T., Rosenmeier, J. B. & Thaning, P., 2012, In: Purinergic Signalling. 8, 2, p. 255-64 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. 2013
    42. Published

      An optimized histochemical method to assess skeletal muscle glycogen and lipid stores reveals two metabolically distinct populations of type I muscle fibers

      Prats Gavalda, Clara, Gomez-Cabello, A., Nordby, P., Andersen, J. L., Helge, Jørn Wulff, Dela, Flemming, Baba, O. & Ploug, Thorkil, 2013, In: PloS one. 8, 10, p. e77774 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Contraction-induced lipolysis is not impaired by inhibition of hormone-sensitive lipase in skeletal muscle

      Alsted, T. J., Ploug, Thorkil, Prats Gavalda, Clara, Serup, A. K., Høeg, L. D., Schjerling, Peter, Holm, C., Zimmermann, R., Fledelius, C., Galbo, Henrik & Kiens, Bente, 2013, In: Journal of Physiology. 591, 20, p. 5141-5155 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Myocardial impulse propagation is impaired in right ventricular tissue of Zucker Diabetic Fatty (ZDF) rats

      Olsen, Kristine Boisen, Axelsen, L. N., Braunstein, T. H., Sorensen, Charlotte Mehlin, Andersen, C. B., Ploug, Thorkil, von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, 2013, In: Cardiovascular Diabetology. 12, p. 19 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Human skeletal muscle perilipin 2 and 3 expression varies with insulin sensitivity

      Vigelsø Hansen, A., Prats Gavalda, Clara, Ploug, Thorkil, Dela, Flemming & Helge, Jørn Wulff, May 2013, In: Journal of Biomedical Science and Engineering. 6, 5A, p. 65-72 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Exercise training favors increased insulin-stimulated glucose uptake in skeletal muscle in contrast to adipose tissue: A randomized study using FDG PET imaging

      Reichkendler, M. H., Auerbach, P. L., Larsen, M. R., Christensen, A. N., Holm, S., Blond, Martin Bæk, Lagerberg, A., Larsson, Henrik Bo Wiberg, Rostrup, Egill, Mosbech, T. H., Sjödin, Anders Mikael, Kjær, Andreas, Ploug, Thorkil, Højgaard, Liselotte & Stallknecht, Bente Merete, 15 Aug 2013, In: American Journal of Physiology: Endocrinology and Metabolism. 305, 4, p. E496-506 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Differential effects of endurance training and weight loss on plasma adiponectin multimers and adipose tissue macrophages in younger, moderately overweight men

      Auerbach, P., Nordby, P., Bendtsen, L. Q., Mehlsen, J. L., Basnet, S. K., drb459, drb459, Ploug, Thorkil & Stallknecht, Bente Merete, 1 Sep 2013, In: A J P: Regulatory, Integrative and Comparative Physiology (Online). 305, p. R490-498 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Appetite regulation in overweight, sedentary men after different amounts of endurance exercise: a randomized controlled trial

      Larsen, M. R., Reichkendler, M. H., Auerbach, P., Toräng, S., Gram, A. S., Ploug, Thorkil, Holst, Jens Juul, Sjödin, Anders Mikael & Stallknecht, Bente Merete, Dec 2013, In: Journal of Applied Physiology. 115, 11, p. 1599-1609 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. 2014
    50. Published

      Compliance with physical exercise: Using a multidisciplinary approach within a dose-dependent exercise study of moderately overweight men

      Gram, A. S., Bønnelycke, J., Rosenkilde Larsen, M., Reichkendler, M. H., Auerbach, P. L., Sjödin, Anders Mikael, Ploug, Thorkil, Jespersen, Astrid Pernille & Stallknecht, Bente Merete, 2014, In: Scandinavian Journal of Public Health. 42, 1, p. 38-44 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    51. Published

      Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction

      Sun, K., Park, J., Gupta, O. T., Holland, W. L., Auerbach, P., Zhang, N., Goncalves Marangoni, R., Nicoloro, S. M., Czech, M. P., Varga, J., Ploug, Thorkil, An, Z. & Scherer, P. E., Mar 2014, In: Nature Communications. 5, 1 p., 3485.

      Research output: Contribution to journalJournal articleResearchpeer-review

    52. Published

      Calibrated image-derived input functions for the determination of the metabolic uptake rate of glucose with [18F]-FDG PET

      Christensen, Anders, Reichkendler, M. H., Larsen, R., Auerbach, P., Højgaard, Liselotte, Nielsen, H. B., Ploug, Thorkil, Stallknecht, Bente Merete & Holm, S., Apr 2014, In: Nuclear Medicine Communications. 35, 4, p. 353-61 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    53. Published

      Only minor additional metabolic health benefits of high as opposed to moderate dose physical exercise in young, moderately overweight men

      Reichkendler, M. H., Larsen, M. R., Auerbach, P. L., Agerschou, J., Nielsen, M. B., Kjær, Andreas, Højgaard, Liselotte, Sjödin, Anders Mikael, Ploug, Thorkil & Stallknecht, Bente Merete, May 2014, In: Obesity. 22, 5, p. 1220-32 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    54. Published

      Biomarkers of coagulation, fibrinolysis, endothelial function, and inflammation in arterialized venous blood

      Gram, A. S., Skov, J., Ploug, Thorkil, Sidelmann, J. J., Stallknecht, Bente Merete & Bladbjerg, E., Jun 2014, In: Blood Coagulation and Fibrinolysis. 25, 4, p. 349-52 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    55. Published

      Skeletal muscle apolipoprotein B expression reduces muscular triglyceride accumulation

      Bartels, Emil Daniel, Ploug, Thorkil, Størling, Joachim, Mandrup-Poulsen, Thomas & Nielsen, L. B., Jun 2014, In: Scandinavian Journal of Clinical & Laboratory Investigation. 74, 4, p. 351-7 7 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    56. 2015
    57. Published

      Changes in peak fat oxidation in response to different doses of endurance training

      Larsen, M. R., Reichkendler, M. H., Auerbach, P., Bonne, T. C., Sjödin, Anders Mikael, Ploug, Thorkil & Stallknecht, Bente Merete, 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, 1, p. 41-52 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    58. Published

      Three months of strictly controlled daily endurance exercise reduces thrombin generation and fibrinolytic risk markers in younger moderately overweight men

      Gram, A. S., Bladbjerg, E., Skov, J., Ploug, Thorkil, Sjödin, Anders Mikael, Rosenkilde Larsen, M., Madsen, D. E. & Stallknecht, Bente Merete, 2015, In: European Journal of Applied Physiology. 115, 6, p. 1331-1338 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    59. Published

      Independent effects of endurance training and weight loss on peak fat oxidation in moderately overweight men: a randomized controlled trial

      Nordby, P., Rosenkilde, M., Ploug, Thorkil, Westh, K., Feigh, M., Nielsen, N. B., Helge, Jørn Wulff & Stallknecht, Bente Merete, 1 Apr 2015, In: Journal of Applied Physiology. 118, 7, p. 803-10 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    60. 2016
    61. Published

      Assessment of six commercial plasma small RNA isolation kits using qRT-PCR and electrophoretic separation: higher recovery of microRNA following ultracentrifugation

      Meerson, A. & Ploug, Thorkil, 2016, In: Biology Methods and Protocols. 1, 1, 9 p., bpw003.

      Research output: Contribution to journalJournal articleResearchpeer-review

    62. Published

      Higher muscle content of perilipin 5 and endothelial lipase protein in trained than untrained middle-aged men

      Vigelsø Hansen, A., Prats Gavalda, Clara, Ploug, Thorkil, Dela, Flemming & Helge, Jørn Wulff, 2016, In: Physiological Research. 65, 2, p. 293-302 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 9723