Thomas Jespersen

Thomas Jespersen

Professor

Member of:


    1. Published

      Structural and electro-anatomical characterization of the equine pulmonary veins: implications for atrial fibrillation

      Kjeldsen, S. T., Nissen, Sarah Dalgas, Saljic, Arnela, Hesselkilde, E. M., Carstensen, Helena, Sattler, Stefan M, Jespersen, Thomas, Dr Linz, Dominik Karl, Hopster-Iversen, Charlotte, Kutieleh, R., Sanders, P. & Buhl, Rikke, 2024, In: Journal of Veterinary Cardiology. 52, p. 1-13

      Research output: Contribution to journalJournal articleResearchpeer-review

    2. Published

      An ERG channel inhibitor from the scorpion Buthus eupeus

      Korolkova, Y. V., Kozlov, S. A., Lipkin, A. V., Pluzhnikov, K. A., Hadley, J. K., Filippov, A. K., Brown, D. A., Pedersen, K. A., Strøbaek, D., Jespersen, Thomas, Olesen, Søren-Peter, Jensen Skanning, B. & Grishin, E. V., 30 Mar 2001, In: Journal of Biological Chemistry. 276, 13, p. 9868-76 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Brugada syndrome unmasked by accidental inhalation of gasoline vapors.

      Kranjcec, D., Bergovec, M., Rougier, J., Raguz, M., Pavlovic, S., Jespersen, Thomas, Castella, V., Keller, D. I. & Abriel, H., 2007, In: Pacing and Clinical Electrophysiology. 30, 10, p. 1294-8 4 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      Necropsy Validation of a Novel Method for Left Ventricular Mass Quantification in Porcine Transthoracic and Transdiaphragmal Echocardiography

      Kristensen, C. B., Sattler, Stefan M, Lubberding, Anniek Frederike, Tfelt-Hansen, Jacob, Jespersen, Thomas, Hassager, Christian & Mogelvang, R., 2022, In: Frontiers in Cardiovascular Medicine. 9, 868603.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels

      Krzystanek, K., Rasmussen, Hanne Borger, Grunnet, Morten, Staub, O., Olesen, Søren-Peter, Abriel, H. & Jespersen, Thomas, 2012, In: Heart Rhythm. 9, 3, p. 440-8 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Published

      Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current.

      Larsen, A. P., Olesen, Søren-Peter, Grunnet, Morten & Jespersen, Thomas, 2008, In: Pflügers Archiv: European Journal of Physiology. 456, 6, p. 1137-48 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts

      Laursen, M., Grunnet, Morten, Olesen, Søren-Peter, Jespersen, Thomas & Mow, T., 2012, In: Journal of Pharmacological and Toxicological Methods. 64, 2, p. 134-44 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Characterization of cardiac repolarization in the Göttingen minipig

      Laursen, M., Olesen, Søren-Peter, Grunnet, Morten, Mow, T., Jespersen, T. & Jespersen, Thomas, 2011, In: Journal of Pharmacological and Toxicological Methods. 63, 2, p. 186-95 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

      Liang, B., Nissen, J. D., Laursen, M., Wang, X., Skibsbye, L., Hearing, M. C., Andersen, M. N., Rasmussen, Hanne Borger, Wickman, K., Grunnet, Morten, Olesen, Søren-Peter & Jespersen, Thomas, 1 Jan 2014, In: Cardiovascular Research. 101, 1, p. 175-84 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Pharmacological inhibition of acetylcholine-regulated potassium current (IK,ACh) prevents atrial arrhythmogenic changes in a rat model of repetitive obstructive respiratory events

      Linz, Benedikt Maximilian, Thostrup, A. H., Saljic, Arnela, Rombouts, K., Hertel, Julie Norup, Hohl, M., Milnes, J., Tfelt-Hansen, Jacob, Dr Linz, Dominik Karl & Jespersen, Thomas, Feb 2022, In: Heart Rhythm O2. 3, 1, p. 97-104

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Mechanisms and Therapeutic Opportunities in Atrial Fibrillation in Relationship to Alcohol Use and Abuse

      Linz, Benedikt Maximilian, Hertel, Julie Norup, Jespersen, Thomas & Dr Linz, Dominik Karl, 2022, In: Canadian Journal of Cardiology. 38, 9, p. 1352-1363

      Research output: Contribution to journalReviewResearchpeer-review

    12. Published

      Repeated exposure to transient obstructive sleep apnea–related conditions causes an atrial fibrillation substrate in a chronic rat model

      Linz, Benedikt Maximilian, Hohl, M., Lang, L., Wong, D. W. L., Nickel, A. G., De La Torre, C., Sticht, C., Wirth, K., Boor, P., Maack, C., Speer, T., Jespersen, Thomas, Schotten, U., Sanders, P., Böhm, M. & Dr Linz, Dominik Karl, 2021, In: Heart Rhythm. 18, 3, p. 455-464

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Sleep apnea and atrial fibrillation: challenges in clinical and translational research

      Linz, Benedikt Maximilian, Hertel, Julie Norup, Hendriks, J., Saljic, Arnela, Dobrev, D., Baumert, M., Jespersen, Thomas & Dr Linz, Dominik Karl, 2022, In: Expert Review of Cardiovascular Therapy. 20, 2, p. 101-109

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Inhibition of sodium-proton-exchanger subtype 3-mediated sodium absorption in the gut: A new antihypertensive concept

      Linz, Benedikt Maximilian, Saljic, Arnela, Hohl, M., Gawalko, M., Jespersen, Thomas, Sanders, P., Bohm, M. & Dr Linz, Dominik Karl, 2020, In: IJC Heart and Vasculature. 29, 7 p., 100591.

      Research output: Contribution to journalReviewResearchpeer-review

    15. Published

      Arrhythmogenic mechanisms of acute obstructive respiratory events in a porcine model of drug-induced Long-QT

      Linz, Benedikt Maximilian, Sattler, Stefan M, Flethoj, M., Høtbjerg Hansen, M. E., Hesselkilde, E. M., Saljic, Arnela, Wirth, K., Dr Linz, Dominik Karl, Tfelt-Hansen, Jacob & Jespersen, Thomas, 2021, In: Heart Rhythm. 18, 8, p. 1384-1391

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Pharmacological inhibition of SK-channels with AP14145 prevents atrial arrhythmogenic changes in a porcine model for obstructive respiratory events

      Linz, Benedikt Maximilian, Hesselkilde, E. M., Skarsfeldt, M. A., Hertel, Julie Norup, Sattler, Stefan M, Yan, Y., Tfelt-Hansen, Jacob, Diness, Jonas Goldin, Bentzen, Bo Hjorth, Dr Linz, Dominik Karl & Jespersen, Thomas, 2023, In: Journal of Cardiovascular Electrophysiology. 34, 1, p. 126-134 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      Pharmacological inhibition of sodium-proton-exchanger subtype 3-mediated sodium absorption in the gut reduces atrial fibrillation susceptibility in obese spontaneously hypertensive rats

      Linz, Benedikt Maximilian, Hohl, M., Mishima, R., Saljic, Arnela, Lau, D. H., Jespersen, Thomas, Schotten, U., Sanders, P. & Dr Linz, Dominik Karl, 2020, In: IJC Heart and Vasculature. 28, 7 p., 100534.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Pulmonary vein firing initiating atrial fibrillation in the horse: Oversized dimensions but similar mechanisms

      Dr Linz, Dominik Karl, Hesselkilde, E., Kutieleh, R., Jespersen, Thomas, Buhl, Rikke & Sanders, P., 2020, In: Journal of Cardiovascular Electrophysiology. 31, 5, p. 1211-1212

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Personalized management of sleep apnea in patients with atrial fibrillation: An interdisciplinary and translational challenge

      Dr Linz, Dominik Karl, Linz, Benedikt Maximilian, Dobrev, D., Baumert, M., Hendriks, J. M., Pepin, J. L. & Jespersen, Thomas, 2021, In: IJC Heart and Vasculature. 35, 100843.

      Research output: Contribution to journalEditorialResearchpeer-review

    20. Published

      Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V

      Lubberding, Anniek Frederike, Zhang, J., Lundh, M., Nielsen, Thomas Svava, Søndergaard, M. S., Villadsen, M., Skovhøj, E. Z., Boer, G. A., Hansen, J. B., Thomsen, Morten Bækgaard, Treebak, Jonas Thue, Holst, Jens Juul, Kanters, Jørgen K., Mandrup-Poulsen, Thomas, Jespersen, Thomas, Emanuelli, Brice & Torekov, Signe Sørensen, 2021, In: Scientific Reports. 11, 1, 14 p., 12253.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Arrhythmia development during inhibition of small-conductance calcium-activated potassium channels in acute myocardial infarction in a porcine model

      Lubberding, Anniek Frederike, Sattler, Stefan M, Grunnet, Morten, Sørensen, U. S., Tfelt-Hansen, Jacob & Jespersen, Thomas, Oct 2019, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 21, 10, p. 1584–1593

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Comparison of hemodynamics, cardiac electrophysiology and ventricular arrhythmia in an open and a closed chest porcine model of acute myocardial infarction

      Lubberding, Anniek Frederike, Sattler, Stefan M, Flethøj, M., Tfelt-Hansen, Jacob & Jespersen, Thomas, 2020, In: American Journal of Physiology: Heart and Circulatory Physiology. 318, 2, p. H391-H400

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Kredsløbet ændres ved overvægt i barndommen

      Lund, Morten Asp Vonsild, Holm, Jens-Christian, Jespersen, Thomas & von Holstein-Rathlou, Niels-Henrik, 2017, In: Ugeskrift for Laeger. 2018, 6, p. 2-6 5 p., V03170265.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Nationwide Burden of Sudden Cardiac Death: A Study of 54,028 Deaths in Denmark

      Lynge, T. H., Risgaard, B., Banner, Jytte, Nielsen, J. L., Jespersen, Thomas, Stampe, N. K., Albert, C. M., Winkel, B. G. & Tfelt-Hansen, Jacob, 2021, In: Heart Rhythm. 18, 10, p. 1657-1665

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Combined In-silico and Machine Learning Approaches Toward Predicting Arrhythmic Risk in Post-infarction Patients

      Maleckar, M. M., Myklebust, L., Uv, J., Florvaag, P. M., Strøm, V., Glinge, C., Jabbari, R., Vejlstrup, N., Engstrøm, Thomas, Ahtarovski, K., Jespersen, Thomas, Tfelt-Hansen, Jacob, Naumova, V. & Arevalo, H., 2021, In: Frontiers in Physiology. 12, 745349.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      From CMR Image to Patient-Specific Simulation and Population-Based Analysis: Tutorial for an Openly Available Image-Processing Pipeline

      Marciniak, M., Arevalo, H., Tfelt-Hansen, Jacob, Jespersen, Thomas, Jabbari, R., Glinge, C., Ahtarovski, K. A., Vejlstrup, N., Engstrøm, Thomas, Maleckar, M. M. & McLeod, K., 1 Jan 2017, Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges - 7th International Workshop, STACOM 2016 Held in Conjunction with MICCAI 2016, Revised Selected Papers. Springer, p. 106-117 12 p. (Lecture Notes in Computer Science, Vol. 10124 LNCS).

      Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    27. Published

      A Multiple Kernel Learning Framework to Investigate the Relationship Between Ventricular Fibrillation and First Myocardial Infarction

      Marciniak, M., Arevalo, H., Tfelt-Hansen, Jacob, Ahtarovski, K. A., Jespersen, Thomas, Jabbari, R., Glinge, C., Vejlstrup, N., Engstrøm, Thomas, Maleckar, M. M. & McLeod, K., 1 Jan 2017, Functional Imaging and Modelling of the Heart: 9th International Conference, FIMH 2017, Toronto, ON, Canada, June 11-13, 2017, Proceedings. Springer, p. 161-171 11 p. (Lecture Notes in Computer Science, Vol. 10263 LNCS).

      Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    28. Published

      Intrinsic Electrical Remodeling Underlies Atrioventricular Block in Athletes

      Mesirca, P., Nakao, S., Nissen, S. D., Forte, G., Anderson, C., Trussell, T., Li, J., Cox, C., Zi, M., Logantha, S., Yaar, S., Cartensen, H., Bidaud, I., Stuart, L., Soattin, L., Morris, G. M., Da Costa Martins, P. A., Cartwright, E. J., Oceandy, D., Mangoni, M. E. & 5 others, Jespersen, Thomas, Buhl, Rikke, Dobrzynski, H., Boyett, M. R. & D'Souza, A., 2021, In: Circulation Research. 129, 1, p. E1-E20

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Published

      Pharmacological rescue of mutated K(v)3.1 ion-channel linked to progressive myoclonus epilepsies

      Munch, A. S., Saljic, Arnela, Boddum, K., Grunnet, Morten, Hougaard, C. & Jespersen, Thomas, 2018, In: European Journal of Pharmacology. 833, p. 255-262

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Attenuated ventricular β-adrenergic response and reduced repolarization reserve in a rabbit model of chronic heart failure

      Nissen, J. D., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Diness, Jonas Goldin, Diness, T. G., Jespersen, Thomas & Grunnet, Morten, 2012, In: Journal of Cardiovascular Pharmacology. 59, 2, p. 142-150 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Pharmacologically induced long QT type 2 can be rescued by activation of IKs with benzodiazepine R-L3 in isolated guinea pig cardiomyocytes

      Nissen, J. D., Diness, Jonas Goldin, Diness, T. G., Hansen, R. S., Grunnet, Morten & Jespersen, Thomas, 2009, In: Journal of Cardiovascular Pharmacology. 54, 2, p. 169-77 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      Electrocardiographic characteristics of trained and untrained standardbred racehorses

      Nissen, Sarah Dalgas, Weis, R., Krag-Andersen, E. K., Hesselkilde, E. M., Isaksen, Jonas L., Carstensen, Helena, Kanters, Jørgen K., Dr Linz, Dominik Karl, Sanders, P., Hopster-Iversen, Charlotte, Jespersen, Thomas, Pehrson, S. & Buhl, Rikke, 2022, In: Journal of Veterinary Internal Medicine. 36, 3, p. 1119-1130

      Research output: Contribution to journalJournal articleResearchpeer-review

    33. Published
    34. Published

      Muscarinic acetylcholine receptors M2 are upregulated in the atrioventricular nodal tract in horses with a high burden of second-degree atrioventricular block

      Nissen, Sarah Dalgas, Saljic, Arnela, Carstensen, Helena, Braunstein, T. H., Hesselkilde, E. M., Kjeldsen, S. T., Hopster-Iversen, Charlotte, D’Souza, A., Jespersen, Thomas & Buhl, Rikke, 2023, In: Frontiers in Cardiovascular Medicine. 10, 10 p., 1102164.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. E-pub ahead of print
    36. Published

      High Prevalence of Long QT Syndrome Associated SCN5A Variants in Patients with Early-Onset Lone Atrial Fibrillation

      Olesen, M. S., Yuan, L., Liang, B., Holst, A. G., Nielsen, N., Nielsen, J. B., Hedley, P. L., Christiansen, M., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole, Jespersen, Thomas & Svendsen, Jesper Hastrup, 2012, In: Circulation: Cardiovascular Genetics. 5, 4, p. 450-459 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    37. Published

      A Novel Nonsense Variant in Nav1.5 Cofactor MOG1 Eliminates Its Sodium Current Increasing Effect and May Increase the Risk of Arrhythmias

      Olesen, M. S., Jensen, N. F., Holst, A. G., Nielsen, J. B., Tfelt-Hansen, Jacob, Jespersen, Thomas, Sajadieh, Ahmad, Haunsø, Stig, Lund, J. T., Callø, Kirstine, Schmitt, Nicole & Svendsen, Jesper Hastrup, 26 May 2011, In: Canadian Journal of Cardiology. 27, 4, p. 523.e17-23

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Mutations in sodium channel {beta}-subunit SCN3B are associated with early-onset lone atrial fibrillation

      Olesen, M. S., Jespersen, Thomas, Nielsen, J. B., Liang, B., Møller, D. V., Hedley, P., Christiansen, M., Varro, A., Olesen, Søren-Peter, Haunsø, Stig, Schmitt, Nicole & Svendsen, Jesper Hastrup, 2011, In: Cardiovascular Research. 89, 4, p. 786-793 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    39. Published

      Screening of KCNN3 in patients with early-onset lone atrial fibrillation

      Olesen, M. S., Jabbari, J., Holst, A. G., Nielsen, J. B., Steinbrüchel, D. A., Jespersen, T., Haunsø, Stig, Svendsen, Jesper Hastrup & Jespersen, Thomas, 2011, In: Europace. 13, 7, p. 963-967 5 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    40. Published

      Time matters: characterization of fibroblast-like cells harvested from pig profundus tendon stored at room temperature at different postmortem time intervals

      Ozhathil, Lijo Cherian, Chen, Y., Nissen, Sarah Dalgas, Banner, Jytte, Tfelt-Hansen, Jacob & Jespersen, Thomas, 2022, In: In Vitro Cellular and Developmental Biology - Animal. 58, p. 633–637

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Clinical Implications of SCN10A Loss-of-Function Variants in 169 610 Exomes Representing the General Population.

      Paludan-Müller, Christian, Larsen, S., Ahlberg, G., Monfort, L. M., Andreasen, L., Svendsen, Jesper Hastrup, Jespersen, Thomas, Bundgård, Henning, Kanters, Jørgen K. & Olesen, Morten Steen Salling, 2022, In: Circulation. Genomic and precision medicine. 15, 1, p. 83-85 3 p., e003574.

      Research output: Contribution to journalLetterResearchpeer-review

    42. Published

      Subtype-specific, bi-component inhibition of SK channels by low internal pH.

      Peitersen, T., Jespersen, Thomas, Jorgensen, N. K., Olesen, Søren-Peter & Grunnet, Morten, 2006, In: Biochemical and Biophysical Research Communications. 343, 3, p. 943-9 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Muscarinic Receptor Activation Reduces Force and Arrhythmias in Human Atria Independent of IK,ACh

      Petersen, J., Castro, L., Bengaard, A. K. P., Pecha, S., Ismaili, D., Schulz, C., Sahni, J., Steenpass, A., Meier, C., Reichenspurner, H., Jespersen, Thomas, Eschenhagen, T. & Christ, T., 2022, In: Journal of Cardiovascular Pharmacology. 79, 5, p. 678-686

      Research output: Contribution to journalJournal articleResearchpeer-review

    44. Published

      Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome.

      Petitprez, S., Jespersen, Thomas, Pruvot, E., Keller, D. I., Corbaz, C., Schläpfer, J., Abriel, H. & Kucera, J. P., 2008, In: Cardiovascular Research. 78, 3, p. 494-504 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. Published

      Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation

      Poulet, C., Wettwer, E., Grunnet, Morten, Jespersen, Thomas, Fabritz, L., Matschke, K., Knaut, M. & Ravens, U., 29 Jun 2015, In: PLOS ONE. 10, 6, p. 1-19 19 p., e0131432.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Utility of left atrial strain for predicting atrial fibrillation following ischemic stroke

      Rasmussen, S. M. A., Olsen, F. J., Jorgensen, P. G., Fritz-Hansen, T., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2019, In: International Journal of Cardiovascular Imaging. 35, 9, p. 1605-1613

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      Change in global longitudinal strain following acute coronary syndrome and subsequent risk of heart failure

      Ravnkilde, K., Skaarup, K. G., Grove, G. L., Modin, D., Nielsen, A. B., Falsing, M. M., Iversen, A. Z., Pedersen, S., Fritz-Hansen, T., Galatius, S., Jespersen, Thomas, Shah, A., Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2021, In: International Journal of Cardiovascular Imaging. 37, p. 3193–3202

      Research output: Contribution to journalJournal articleResearchpeer-review

    48. Published

      Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins.

      Rougier, J., van Bemmelen, M. X., Bruce, M. C., Jespersen, Thomas, Gavillet, B., Apothéloz, F., Cordonier, S., Staub, O., Rotin, D. & Abriel, H., 2004, In: American Journal of Physiology: Cell Physiology. 288, 3, p. C692-701

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published
    50. Published

      Anti-arrhythmic investigations in large animal models of atrial fibrillation

      Saljic, Arnela, Jespersen, Thomas & Buhl, Rikke, 2022, In: British Journal of Pharmacology. 179, 5, p. 838-858

      Research output: Contribution to journalReviewResearchpeer-review

    ID: 8117