Thomas Jespersen

Thomas Jespersen

Professor

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    ORCID: 0000-0001-6575-360X

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    1. Published

      Usefulness of left atrial strain for predicting incident atrial fibrillation and ischaemic stroke in the general population

      Alhakak, Alia Saed, Biering-Sørensen, S. R., Møgelvang, R., Modin, D., Jensen, G. B., Schnohr, P., Iversen, A. Z., Svendsen, Jesper Hastrup, Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2022, In: European heart journal. Cardiovascular Imaging. 23, 3, p. 363-371 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      AMP-activated protein kinase downregulates Kv7.1 cell surface expression

      Andersen, M. N., Krzystanek, K., Jespersen, Thomas, Olesen, Søren-Peter & Rasmussen, Hanne Borger, 2012, In: Traffic. 13, 1, p. 143-56 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

      Andersen, M. N., Krzystanek, K., Petersen, F., Bomholtz, Sofia Hammami, Olesen, Søren-Peter, Abriel, H., Jespersen, Thomas & Rasmussen, Hanne Borger, 8 Nov 2013, In: The Journal of Biological Chemistry. 288, 52, p. 36841-54 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Regulation of Kv1.4 potassium channels by PKC and AMPK kinases

      Andersen, M. N., Skibsbye, L., Saljic, Arnela, Larsen, M. Z., Rasmussen, Hanne Borger & Jespersen, Thomas, 20 Dec 2018, In: Channels (Austin). 12, 1, p. 34-44

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      PKC and AMPK regulation of Kv1.5 potassium channels

      Andersen, M. N., Skibsbye, L., Tang, C., Petersen, F., MacAulay, Nanna, Rasmussen, Hanne Borger & Jespersen, Thomas, 2015, In: Channels (Austin). 9, 3, p. 121-8 8 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    6. Published

      Next-generation sequencing of AV nodal reentrant tachycardia patients identifies broad spectrum of variants in ion channel genes

      Andreasen, Laura Korsholm, Ahlberg, G., Tang, C., Andreasen, C., Hartmann, J. P., Tfelt-Hansen, Jacob, Behr, E. R., Pehrson, S., Haunsø, Stig, LuCamp, Weeke, P. E., Jespersen, Thomas, Olesen, Morten Steen Salling & Svendsen, Jesper Hastrup, 2018, In: European Journal of Human Genetics. 26, p. 660–668

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.

      Angelo, K., Jespersen, Thomas, Grunnet, Morten, Nielsen, Morten Schak, Klærke, Dan Arne & Olesen, Søren-Peter, 2002, In: Biophysical Journal. 83, 4, p. 1997-2006 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

      Axelsen, L. N., Callø, Kirstine, Braunstein, T. H., Riemann, Mads, Hofgaard, J. P., Liang, B., Jensen, C. F., Olsen, Kristine Boisen, Bartels, Emil Daniel, Baandrup, U., Jespersen, Thomas, Nielsen, L. B., von Holstein-Rathlou, Niels-Henrik & Nielsen, Morten Schak, 14 Jul 2015, In: Cardiovascular Diabetology. 14, 14 p., 87.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Mutational library analysis of selected amino acids in the receptor binding domain of envelope of Akv murine leukemia virus by conditionally replication competent bicistronic vectors

      Bahrami, S., Jespersen, T., Pedersen, F. S., Duch, M. R. & Jespersen, Thomas, 2 Oct 2003, In: Gene. 315, p. 51-61 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Researchers in cardiology – Why and how to get on Twitter?

      Benjamin Fyenbo, D., Charlotte Frederiksen, T., Dr Linz, Dominik Karl, Jespersen, Thomas, Dobrev, D., Gislason, Gunnar Hilmar, Betz, K., Saljic, Arnela & Nielsen Holck, E., 2022, In: IJC Heart and Vasculature. 40, 101010.

      Research output: Contribution to journal › Review › Research › peer-review

    11. Published

      [68Ga]Ga-NODAGA-E[(cRGDyK)]2 Angiogenesis PET/MR in a Porcine Model of Chronic Myocardial Infarction

      Bentsen, Simon, Clemmensen, Andreas Høeg, Loft, Mathias Hougaard, Flethøj, M., Debes, Karina Poulsdóttir, Ludvigsen, Trine Pagh, Larsen, C. B., Kirchhoff, J., Olsen, Lisbeth Høier, Møller, J. E., Andersen, Thomas Lund, Johannesen, Helle Hjorth, Jespersen, Thomas & Kjær, Andreas, 2021, In: Diagnostics. 11, 10, 1807.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury

      Bentzen, Bo Hjorth, Osadchii, O., Jespersen, Thomas, Hansen, R. S., Olesen, Søren-Peter & Grunnet, Morten, 2009, In: Pflügers Archiv: European Journal of Physiology. 457, 5, p. 979-88 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      The arrhythmogenic calmodulin mutation D129G dysregulates cell growth, calmodulin-dependent kinase II activity, and cardiac function in zebrafish

      Berchtold, Martin Werner, Zacharias, T., Kulej, K., Wang, K., Torggler, R., Jespersen, Thomas, Chen, J. N., Larsen, M. R. & la Cour, J. M., 2016, In: Journal of Biological Chemistry. 291, 52, p. 26636-26646 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Kv3.1/Kv3.2 channel positive modulators enable faster activating kinetics and increase firing frequency in fast-spiking GABAergic interneurons

      Boddum, K., Hougaard, C., Xiao-Ying Lin, J., von Schoubye, N. L., Jensen, H. S., Grunnet, M. & Jespersen, Thomas, 2017, In: Neuropharmacology. 118, p. 102-112 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      A Novel SCN5A Variant Associated with Abnormal Repolarization, Atrial Fibrillation, and Reversible Cardiomyopathy

      Boddum, K., Saljic, Arnela, Jespersen, Thomas & Christensen, A. H., 2018, In: Cardiology. 140, 1, p. 8-13

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Solid-phase synthesis and biological activity of a thioether analogue of conotoxin G1.

      Bondebjerg, J., Grunnet, Morten, Jespersen, Thomas & Meldal, Morten Peter, 2003, In: ChemBioChem. 4, 2-3, p. 186-94 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Early systolic lengthening in patients with ST-segment elevation myocardial infarction: a novel predictor of cardiovascular events

      Brainin, P., Haahr-Pedersen, S., Olsen, F. J., Fritz-Hansen, T., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2019, In: European Heart Journal. 40, Suppl. 1, p. 718-718 1 p., 1270 .

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    18. Published

      Early Systolic Lengthening in Patients With ST-Segment-Elevation Myocardial Infarction: A Novel Predictor of Cardiovascular Events

      Brainin, P., Haahr-Pedersen, S., Olsen, F. J., Holm, A. E., Fritz-Hansen, T., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2020, In: Journal of the American Heart Association. 9, 3, p. e013835

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Implantable loop recorders can detect paroxysmal atrial fibrillation in Standardbred racehorses with intermittent poor performance

      Buhl, Rikke, Nissen, Sarah Dalgas, Winther, M. L. K., Poulsen, S. K., Hopster-Iversen, Charlotte, Jespersen, Thomas, Sanders, P., Carstensen, Helena & Hesselkilde, E. M., 2021, In: Equine Veterinary Journal. 53, 5, p. 955-963

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Detection of atrial fibrillation with implantable loop recorders in horses

      Buhl, Rikke, Hesselkilde, E. M., Carstensen, Helena, Fenner, Merle Friederike, Jespersen, Thomas, Tfelt-Hansen, Jacob & Sattler, Stefan M, 2021, In: Equine Veterinary Journal. 53, 2, p. 397-403

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Effect of induced chronic atrial fibrillation on exercise performance in Standardbred trotters

      Buhl, Rikke, Carstensen, Helena, Hesselkilde, E. Z., Klein, B. Z., Hougaard, K. M., Ravn, K. B., Loft-Andersen, A. V., Fenner, Merle Friederike, Pipper, C. & Jespersen, Thomas, 2018, In: Journal of Veterinary Internal Medicine. 32, 4, p. 1410-1419 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

      Callø, Kirstine, Soltysinska, E., Jespersen, Thomas, Lundby, Alicia, Antzelevitch, C., Olesen, Søren-Peter & Cordeiro, J. M., 2009, In: Journal of Molecular and Cellular Cardiology. 48, 1, p. 191-200 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Comparison of the Effects of a Transient Outward Potassium Channel Activator on Currents Recorded from Atrial and Ventricular Cardiomyocytes.

      Callø, Kirstine, Nof, E., Jespersen, Thomas, Di Diego, J. M., Chlus, N., Olesen, Søren-Peter, Antzelevitch, C. & Cordeiro, J. M., 2011, In: Journal of Cardiovascular Electrophysiology. 22, 9, p. 1057-1066 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Time-dependent antiarrhythmic effects of flecainide on induced atrial fibrillation in horses

      Carstensen, Helena, Hesselkilde, E. Z., Fenner, Merle Friederike, Loft-Andersen, A. V., Flethøj, M., Kanters, Jørgen K., Sattler, Stefan M, Tfelt-Hansen, Jacob, Pehrson, S., Jespersen, Thomas & Buhl, Rikke, 2018, In: Journal of Veterinary Internal Medicine. 32, 5, p. 1708-1717 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Antiarrhythmic Effects of Combining Dofetilide and Ranolazine in a Model of Acutely Induced Atrial Fibrillation in Horses

      Carstensen, Helena, Kjær, L., Haugaard, M. M., Flethøj, M., Hesselkilde, E. Z., Kanters, Jørgen K., Pehrson, S., Buhl, Rikke & Jespersen, Thomas, Jan 2018, In: Journal of Cardiovascular Pharmacology. 71, 1, p. 26-35 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Effects of dofetilide and ranolazine on atrial fibrillatory rate in a horse model of acutely induced atrial fibrillation

      Carstensen, Helena, Hesselkilde, E. Z., Haugaard, M. M., Flethøj, M., Carlson, J., Pehrson, S., Jespersen, Thomas, Platonov, P. G. & Buhl, Rikke, 2019, In: Journal of Cardiovascular Electrophysiology. 30, 4, p. 596-606

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Long-Term Training Increases Atrial Fibrillation Sustainability in Standardbred Racehorses

      Carstensen, Helena, Nissen, Sarah Dalgas, Saljic, Arnela, Hesselkilde, E. M., van Hunnik, A., Hohl, M., Sattler, Stefan M, Fløgstad, C., Hopster-Iversen, Charlotte, Verheule, S., Böhm, M., Schotten, U., Jespersen, Thomas & Buhl, Rikke, 2023, In: Journal of Cardiovascular Translational Research. 16, p. 1205–1219

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Decreased Heart Rate After Dapagliflozin Treatment In Gottingen Minipigs With Chronic Myocardial Infarction

      Debes, Karina Poulsdóttir, Lyhne, Mille Kronborg, Hinz, K., Sand, K. P., Rose, V. H., Flethøj, M., Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2024, In: Journal of Cardiac Failure. 30, 1, p. 267-268

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    29. Published

      Antiarrhythmic effect of IKr activation in a cellular model of LQT3

      Diness, Jonas Goldin, Hansen, R. S., Nissen, J. D., Jespersen, Thomas & Grunnet, Morten, 2008, In: Heart Rhythm. 6, 1, p. 100-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Effects on atrial fibrillation in aged hypertensive rats by Ca(2+)-activated K(+) channel inhibition

      Diness, Jonas Goldin, Skibsbye, L., Jespersen, Thomas, Bartels, Emil Daniel, Sørensen, U. S., Hansen, R. S. & Grunnet, Morten, 2011, In: Hypertension. 57, 6, p. 1129-35 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

      Diness, Jonas Goldin, Skibsbye, L., Simó-Vicens, R., Louro Larupa dos Santos, J., Lundegaard, Pia Rengtved, Citerni, C., Sauter, D. R. P., Bomholtz, Sofia Hammami, Svendsen, Jesper Hastrup, Olesen, Søren-Peter, Sørensen, U. S., Jespersen, Thomas, Grunnet, Morten & Bentzen, Bo Hjorth, 10 Oct 2017, In: Circulation: Arrhythmia and Electrophysiology. 10, 19 p., e005125.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Antiarrhythmic effect of either negative modulation or blockade of small conductance Ca2+ activated K+ channels on ventricular fibrillation in guinea pig Langendorff perfused heart

      Diness, J. G., Kirchhoff, J. E., Sheykhzade, Majid, Jespersen, Thomas & Grunnet, M., 8 May 2015, In: Journal of Cardiovascular Pharmacology. 66, 3, p. 294–299 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Inhibition of small-conductance Ca2+-activated K+ channels terminates and protects against atrial fibrillation

      Diness, Jonas Goldin, Sørensen, U. S., Nissen, J. D., Al-Shahib, B., Jespersen, T., Grunnet, Morten, Hansen, R. S. & Jespersen, Thomas, Aug 2010, In: Circulation. Arrhythmia and electrophysiology. 3, 4, p. 380-90 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Myocardial performance index by tissue Doppler echocardiography predicts adverse events in patients with atrial fibrillation

      Dons, M., Olsen, F. J., de Knegt, M. C., Fritz-Hansen, T., Mogelvang, R., Alhakak, A. S., Jespersen, Thomas, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, May 2020, In: European Heart Journal Cardiovascular Imaging. 21, 5, p. 560-566

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Nanopore sequencing reveals methylation changes associated with obesity in circulating cell-free DNA from Göttingen Minipigs

      Drag, Markus Hodal, Debes, Karina Poulsdóttir, Franck, C. S., Flethøj, M., Lyhne, Mille Kronborg, Møller, J. E., Ludvigsen, Trine Pagh, Jespersen, Thomas, Olsen, Lisbeth Høier & Kilpeläinen, Tuomas O., 2023, In: Epigenetics. 18, 1, 17 p., 2199374.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Associations between thyroid-stimulating hormone, blood pressure and adiponectin are attenuated in children and adolescents with overweight or obesity

      Drivsholm, A., Lund, Morten Asp Vonsild, Hedley, P. L., Jespersen, Thomas, Christiansen, M., Hansen, Torben & Holm, Jens-Christian, 2019, In: Journal of Pediatric Endocrinology and Metabolism. 32, 12, p. 1351-1358

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Functional testing of a bicistronic retroviral vector for intracellular peptide production

      Duch, M. R., Tolstrup, A., Dalum, I., Jespersen, Thomas, Mouritsen, S. & Pedersen, F. S., 1 Jun 1999, In: BioTechniques. 26, 6, p. 1032-4, 1036

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Transgene stability for three replication-competent murine leukemia virus vectors

      Duch, M. R., Carrasco, M. L., Jespersen, T., Hansen, B. D., Pedersen, F. S. & Jespersen, Thomas, 31 Mar 2004, In: Gene. 329, p. 61-9 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo

      Duch, M. R., Carrasco, M. L., Jespersen, T., Aagaard, L., Pedersen, F. S. & Jespersen, Thomas, 1 Jan 2004, In: Nucleic Acids Symposium Series. 32, 6, p. 2039-48 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Difference in allelic expression of the CLCN1 gene and the possible influence on the myotonia congenita phenotype.

      Dunø, M., Colding-Jørgensen, E., Grunnet, Morten, Jespersen, Thomas, Vissing, John & Schwartz, M., 2004, In: European Journal of Human Genetics. 12, 9, p. 738-43 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Activation of KCNQ5 channels stably expressed in HEK293 cells by BMS-204352.

      Dupuis, D. S., Schrøder, R. L., Jespersen, Thomas, Christensen, J. K., Christophersen, P., Jensen, B. S. & Olesen, Søren-Peter, 2002, In: European Journal of Pharmacology. 437, 3, p. 129-37 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Left atrial functional measurements’ utility in predicting long-term risk of atrial fibrillation after isolated CABG

      Dyhr, M. R., Olsen, F. J., Lindberg, S., Modin, D., Fritz-Hansen, T., Pedersen, S., Iversen, A., Galatius, S., Jespersen, Thomas, Møgelvang, R. & Biering-Sørensen, Tor, 2023, In: Echocardiography. 40, 7, p. 695-702 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Effect of Selective IK,ACh Inhibition by XAF-1407 in an Equine Model of Tachypacing-induced Persistent Atrial Fibrillation (AF)

      Fenner, Merle Friederike, Carstensen, Helena, Nissen, Sarah Dalgas, Hesselkilde, E. Z., Lunddahl, C., Jensen, M. A. H., Loft-Andersen, A. V., Sattler, Stefan M, Platonov, P. G., El-Haou, S., Jackson, C., Tang, R., Kirby, R., Ford, J. W., Schotten, U., Milnes, J. T., Sørensen, U. S., Jespersen, Thomas & Buhl, Rikke, 2020, In: British Journal of Pharmacology. 177, 16, p. 3778-3794

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Inhibition of Small-Conductance Calcium-Activated Potassium Current (IK,Ca) Leads to Differential Atrial Electrophysiological Effects in a Horse Model of Persistent Atrial Fibrillation

      Fenner, Merle Friederike, Gatta, G., Sattler, Stefan M, Kuiper, M., Hesselkilde, E. M., Adler, Ditte Marie Top, Smerup, Morten Holdgaard, Schotten, U., Sørensen, U., Diness, J. G., Jespersen, Thomas, Verheule, S., Van Hunnik, A. & Buhl, Rikke, 2021, In: Frontiers in Physiology. 12, 614483.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Effective termination of atrial fibrillation by SK channel inhibition is associated with a sudden organization of fibrillatory conduction

      Gatta, G., Sobota, V., Citerni, C., Diness, Jonas Goldin, Sørensen, U. S., Jespersen, Thomas, Bentzen, Bo Hjorth, Zeemering, S., Kuiper, M., Verheule, S., Schotten, U. & Van Hunnik, A., 2021, In: Europace. 23, 11, p. 1847-1859 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Gut microbiota, dysbiosis and atrial fibrillation. Arrhythmogenic mechanisms and potential clinical implications

      Gawalko, M., Agbaedeng, T. A., Saljic, Arnela, Mueller, D. N., Wilck, N., Schnabel, R., Penders, J., Rienstra, M., van Gelder, I., Jespersen, Thomas, Schotten, U., Crijns, H. J. G. M., Kalman, J. M., Sanders, P., Nattel, S., Dobrev, D. & Dr Linz, Dominik Karl, 2022, In: Cardiovascular Research. 118, 11, p. 2415–2427

      Research output: Contribution to journal › Review › Research › peer-review

    47. Published

      Adiposity-associated atrial fibrillation: molecular determinants, mechanisms, and clinical significance

      Gawalko, M., Saljic, Arnela, Li, N., Abu-Taha, I., Jespersen, Thomas, Dr Linz, Dominik Karl, Nattel, S., Heijman, J., Fender, A. & Dobrev, D., 2023, In: Cardiovascular Research. 119, 3, p. 614–630 17 p.

      Research output: Contribution to journal › Review › Research › peer-review

    48. Published

      The gut microbial-derived metabolite trimethylamine N-oxide: A missing link between lifestyle-components and atrial fibrillation?

      Gawalko, M., Jespersen, Thomas, Dobrev, D. & Dr Linz, Dominik Karl, 2020, In: IJC Heart and Vasculature. 29, 3 p., 100581.

      Research output: Contribution to journal › Editorial › Research › peer-review

    49. Published

      Stability of Circulating Blood-Based MicroRNAs - Pre-Analytic Methodological Considerations

      Glinge, C., Clauss, S., Boddum, K., Jabbari, R., Jabbari, J., Risgaard, B., Tomsits, P., Hildebrand, B., Kääb, S., Wakili, R., Jespersen, Thomas & Tfelt-Hansen, Jacob, 2017, In: PLOS ONE. 12, 2, 16 p., e0167969.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Pharmacological modulation of SK3 channels

      Grunnet, Morten, Jespersen, Thomas, Angelo, K., Frøkjær-Jensen, Christian, Klærke, Dan Arne, Olesen, Poul & Jensen, B. S., 1 Jun 2001, In: Neuropharmacology. 40, 7, p. 879-887 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      hKCNE4 inhibits the hKCNQ1 potassium current without affecting the activation kinetics.

      Grunnet, Morten, Olesen, Søren-Peter, Klærke, Dan Arne & Jespersen, Thomas, 2005, In: Biochemical and Biophysical Research Communications. 328, 4, p. 1146-53 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      KCNE4 is an inhibitory subunit to the KCNQ1 channel.

      Grunnet, Morten, Jespersen, Thomas, Rasmussen, Hanne Borger, Ljungstrøm, T., Jorgensen, N. K., Olesen, Søren-Peter & Klærke, Dan Arne, 2002, In: Journal of Physiology. 542, Pt 1, p. 119-30 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      KCNE4 is an inhibitory subunit to Kv1.1 and Kv1.3 potassium channels.

      Grunnet, Morten, Rasmussen, H. B., Hay-Schmidt, Anders, Rosenstierne, M., Klærke, Dan Arne, Olesen, Søren-Peter & Jespersen, Thomas, 2003, In: Biophysical Journal. 85, 3, p. 1525-37 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      Characterization of two new dominant ClC-1 channel mutations associated with myotonia.

      Grunnet, Morten, Jespersen, Thomas, Colding-Jørgensen, E., Schwartz, M., Klærke, Dan Arne, Vissing, John, Olesen, Søren-Peter & Dunø, M., 2003, In: Muscle & Nerve. 28, 6, p. 722-32 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. Published

      Recruitment of motor neuronal persistent inward currents shapes withdrawal reflexes in the frog

      Grunnet, Morten, Jespersen, Thomas & Perrier, Jean-Francois Marie, 2004, In: Journal of Neuroscience Research. 78, p. 845-854

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      KCNQ1 channels sense small changes in cell volume.

      Grunnet, Morten, Jespersen, Thomas, MacAulay, Nanna, Jørgensen, N. K., Schmitt, Nicole, Pongs, O., Olesen, Søren-Peter & Klærke, Dan Arne, 2003, In: Journal of Physiology. 549, Pt 2, p. 419-27 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      5-HT1A receptors modulate small-conductance Ca2+-activated K+ channels.

      Grunnet, Morten, Jespersen, Thomas & Perrier, J., 2004, In: Journal of Neuroscience Research. 78, 6, p. 845-54 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Published

      Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses

      Haugaard, M. M., Pehrson, S., Carstensen, Helena, Madsen, M. F., Hesselkilde, E. Z., Præstegaard, K. F., Diness, J. G., Grunnet, M., Jespersen, Thomas & Buhl, Rikke, 2015, In: Journal of Veterinary Internal Medicine. 29, 1, p. 339-347 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses

      Haugaard, M. M., Hesselkilde, E. Z., Pehrson, S. M., Carstensen, Helena, Madsen, M. F., Præstegaard, K. F., Sørensen, U. S., Diness, J. G., Grunnet, M., Buhl, Rikke & Jespersen, Thomas, Apr 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 4, p. 825-835 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Atrieflimmer og elektrofysiologi hos heste

      Haugaard, M. M., Buhl, Rikke & Jespersen, Thomas, 2011, In: Dansk Veterinaertidsskrift. 12, p. 28-31 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. Published

      The role of CAV3 in long-QT syndrome: clinical and functional assessment of a caveolin-3/Kv11.1 double heterozygote versus caveolin-3 single heterozygote

      Hedley, P. L., Kanters, Jørgen K., Dembic, M., Jespersen, Thomas, Skibsbye, L., Aidt, F. H., Eschen, O., Graff, C., Behr, E. R., Schlamowitz, S., Corfield, V., McKenna, W. J. & Christiansen, M., Oct 2013, In: Circulation: Cardiovascular Genetics. 6, 5, p. 452-61 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Enhanced Ca2+-Dependent SK-Channel Gating and Membrane Trafficking in Human Atrial Fibrillation

      Heijman, J., Zhou, X., Morotti, S., Molina, C. E., Abu-Taha, I. H., Tekook, M., Jespersen, Thomas, Zhang, Y., Dobrev, S., Milting, H., Gummert, J., Karck, M., Kamler, M., El-Armouche, A., Saljic, Arnela, Grandi, E., Nattel, S. & Dobrev, D., 2023, In: Circulation Research. 132, 9, p. E116-E133

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Published

      3D-electroanatomical mapping of the left atrium and catheter-based pulmonary vein isolation in pigs: A practical guide

      Hertel, Julie Norup, Jerltorp, K., Hansen, Malthe Emil Høtbjerg, Isaksen, Jonas L., Sattler, Stefan M, Linz, Benedikt Maximilian, Chaldoupi, S. M., Jespersen, Thomas, Saljic, Arnela, Gang, Uffe Jakob Ortved, Manninger, M. & Dr Linz, Dominik Karl, 2023, In: Frontiers in Cardiovascular Medicine. 10, 8 p., 1139364.

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. Published

      First catheter-based high-density endocardial 3D electroanatomical mapping of the right atrium in standing horses

      Hesselkilde, E., Dr Linz, Dominik Karl, Saljic, Arnela, Carstensen, Helena, Kutieleh, R., Jespersen, Thomas, Sanders, P. & Buhl, Rikke, 2021, In: Equine Veterinary Journal. 53, 4, p. 186-193

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. Published

      A novel approach for obtaining 12-lead electrocardiograms in horses

      Hesselkilde, E. M., Isaksen, Jonas L., Petersen, B. V., Carstensen, Helena, Jespersen, Thomas, Pehrson, S., Kanters, Jørgen K. & Buhl, Rikke, 2021, In: Journal of Veterinary Internal Medicine. 35, 1, p. 521-531

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. Published

      Effect of flecainide on atrial fibrillatory rate in a large animal model with induced atrial fibrillation

      Hesselkilde, E. Z., Carstensen, Helena, Haugaard, M. M., Carlson, J., Pehrson, S., Jespersen, Thomas, Buhl, Rikke & Platonov, P. G., Dec 2017, In: B M C Cardiovascular Disorders. 17, 6 p., 289.

      Research output: Contribution to journal › Journal article › Research › peer-review

    67. Published

      Implantable loop recorders for arrhythmia detection - a new promising diagnostic tool for longterm arrhythmia monitoring

      Hesselkilde, E. Z., Carsten, H., Fenner, Merle Friederike, Jespersen, Thomas, T-felt, J., Sattler, Stefan M & Buhl, Rikke, 2019, In: Acta Physiologica. 227, S721, p. 93-93 35.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    68. Published

      Longitudinal study of electrical, functional and structural remodelling in an equine model of atrial fibrillation

      Hesselkilde, E. Z., Carstensen, Helena, Flethøj, M., Fenner, Merle Friederike, Kruse, D. D., Sattler, Stefan M, Tfelt-Hansen, Jacob, Pehrson, S., Braunstein, T. H., Carlson, J., Platonov, P. G., Jespersen, Thomas & Buhl, Rikke, 2019, In: BMC Cardiovascular Disorders. 19, 1, 12 p., 228.

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. Published

      O11 | In vitro and in vivo effects of dapagliflozin on adenosine diphosphate induced platelet aggregation response in Göttingen minipigs

      Hinz, K., Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Reimann, Maria Josefine, Flethøj, M., Bruun, Camilla Vibeke Sichlau, Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Pharmacology and Therapeutics. 46, S1, p. 33 1 p., O11.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    70. Published

      Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts

      Hoeker, G. S., Skarsfeldt, M. A., Jespersen, Thomas & Poelzing, S., Jan 2017, In: Physiological Reports. 5, 1, 10 p., e13120.

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. Published

      Does KCNE5 play a role in long QT syndrome?

      Hofman-Bang, J., Jespersen, Thomas, Grunnet, Morten, Larsen, Lars Allan, Andersen, P. S., Kanters, Jørgen K., Kjeldsen, K. & Christiansen, M., 2004, In: Clinica Chimica Acta. 345, 1-2, p. 49-53 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    72. Published

      Sick sinus syndrome, progressive cardiac conduction disease, atrial flutter and ventricular tachycardia caused by a novel SCN5A mutation

      Holst, A. G., Liang, B., Jespersen, Thomas, Bundgård, Henning, Haunso, S., Svendsen, Jesper Hastrup & Tfelt-Hansen, J., 2010, In: Cardiology. 115, 4, p. 311-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    73. Published

      A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease

      Holst, A. G., Callø, Kirstine, Jespersen, Thomas, Cedergreen, P., Winkel, B. G., Jensen, H. K., Leren, T. P., Haunso, S., Svendsen, Jesper Hastrup & Tfelt-Hansen, J., 2009, In: Case Reports in Medicine. 2009, p. 963645

      Research output: Contribution to journal › Journal article › Research › peer-review

    74. Published

      Functionally Selective AT(1) Receptor Activation Reduces Ischemia Reperfusion Injury

      Hostrup, A., Christensen, G. L., Bentzen, Bo Hjorth, Liang, B., Aplin, M., Grunnet, Morten, Hansen, J. L. & Jespersen, Thomas, 30 Jul 2012, In: Cellular Physiology and Biochemistry. 30, 3, p. 642-652 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    75. Published

      Pharmacological blockade of small conductance Ca-activated K channels by ICA reduces arrhythmic load in rats with acute myocardial infarction

      Hundahl, L. A., Sattler, S. M., Skibsbye, L., Diness, J. G., Tfelt-Hansen, Jacob & Jespersen, Thomas, Jun 2017, In: Pflügers Archiv - European Journal of Physiology. 469, 5-6, p. 739-750 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    76. Published

      Rat Models of Ventricular Fibrillation Following Acute Myocardial Infarction

      Hundahl, L. A., Tfelt-Hansen, Jacob & Jespersen, Thomas, Nov 2017, In: Journal of Cardiovascular Pharmacology and Therapeutics. 22, 6, p. 514-528 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    77. Published

      Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia

      Hyltén-Cavallius, L., Iepsen, E. W., Albrechtsen, Nicolai Jacob Wewer, Svendstrup, M., Lubberding, Anniek Frederike, Hartmann, Bolette, Jespersen, Thomas, Linneberg, Allan René, Christiansen, M., drb459, drb459, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K., Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Circulation. 135, 18, p. 1705-1719 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    78. Published

      Regulation of APD and Force by the Na+/Ca2+ Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue

      Ismaili, D., Gurr, K., Horvath, A., Yuan, L., Lemoine, M. D., Schulz, C., Sani, J., Petersen, J., Reichenspurner, H., Kirchhof, P., Jespersen, Thomas, Eschenhagen, T., Hansen, A., Koivumaeki, J. T. & Christ, T., 2022, In: Cells. 11, 15, 15 p., 2424.

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. Published

      Common and rare variants in SCN10A modulate the risk of atrial fibrillation.

      Jabbari, J., Olesen, Morten Steen Salling, Yuan, L., Nielsen, J. B., Liang, B., Macri, V., Christophersen, I. E., Nielsen, N., Sajadieh, Ahmad, Ellinor, P. T., Grunnet, Morten, Haunsø, Stig, Holst, A. G., Svendsen, Jesper Hastrup & Jespersen, Thomas, 2015, In: Circulation: Cardiovascular Genetics. 8, 1, p. 64-73 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    80. Published

      The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes.

      Jensen, H. S., Callø, Kirstine, Jespersen, Thomas, Jensen, B. S. & Olesen, Søren-Peter, 2005, In: Brain Research. 139, 1, p. 52-62 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. Published

      Effect of Selective IK,ACh Inhibition by XAF-1407 in an Equine Model of Tachypacing-induced Persistent Atrial Fibrillation (AF)

      Jespersen, Thomas, Fenner, Merle Friederike & Buhl, Rikke, 2019, In: Acta Physiologica. 227, S721, p. 96-96

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    82. Published

      Analysis and exploitation of murine leukemia virus cis- and trans-elements using novel transduction systems

      Jespersen, Thomas, 3 Mar 1999

      Research output: Book/Report › Ph.D. thesis › Research

    83. Published

      Expression of heterologous genes from an IRES translational cassette in replication competent murine leukemia virus vectors

      Jespersen, Thomas, Duch, M. R., Carrasco, M. L., Warming, S. & Pedersen, F. S., 1 Nov 1999, In: Gene. 239, 2, p. 227-35 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    84. Published

      Regulation and physiological function of Na(v) 1.5 and KCNQ1 channels

      Jespersen, Thomas, 2011, In: Acta Physiologica (Print). 202 Suppl 683, p. 1-26 26 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    85. Published

      Efficient non-PCR-mediated overlap extension of PCR fragments by exonuclease "end polishing"

      Jespersen, Thomas, Duch, M. R. & Pedersen, F. S., 1 Jul 1997, In: BioTechniques. 23, 1, p. 48, 50, 52

      Research output: Contribution to journal › Journal article › Research › peer-review

    86. Published

      Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1.

      Jespersen, Thomas, Gavillet, B., van Bemmelen, M. X., Cordonier, S., Thomas, M. A., Staub, O. & Abriel, H., 2006, In: Biochemical and Biophysical Research Communications. 348, 4, p. 1455-62 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    87. Published

      The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family.

      Jespersen, Thomas, Membrez, M., Nicolas, C. S., Pitard, B., Staub, O., Olesen, Søren-Peter, Baró, I. & Abriel, H., 2007, In: Cardiovascular Research. 74, 1, p. 64-74 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. Published

      The corticosteroid hormone induced factor: a new modulator of KCNQ1 channels?

      Jespersen, Thomas, Grunnet, Morten, Rasmussen, Hanne Borger, Jørgensen, N. B., Jensen, H., Angelo, K., Olesen, Søren-Peter & Klærke, Dan Arne, 2006, In: Biochemical and Biophysical Research Communications. 341, 4, p. 979-88 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. Published

      Kondo physics in tunable semicondouctor nanowire quantum dots

      Jespersen, Thomas, Aagesen, M., Sørensen, Claus Birger, Lindelof, Poul Erik & Nygård, Jesper, 2006, In: Physical Review B. Condensed Matter and Materials Physics. 74, 23, p. 233304

      Research output: Contribution to journal › Journal article › Research › peer-review

    90. Published

      Cardiac Arrhythmia - new considerations: The Cardiac Ion Channels

      Jespersen, Thomas, 29 Feb 2012, Cardiac Arrhythmias - new considerations. Breijo-Marquez, F. R. (ed.). Croatia: InTech, p. 45-72 29 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    91. Published

      Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif.

      Jespersen, Thomas, Rasmussen, Hanne Borger, Grunnet, Morten, Jensen, H. S., Angelo, K., Dupuis, D. S., Vogel, L. K., Jorgensen, N. K., Klærke, Dan Arne & Olesen, Søren-Peter, 2004, In: Journal of Cell Science. 117, Pt 19, p. 4517-26 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes

      Jespersen, Thomas, Grunnet, Morten, Angelo, K., Klærke, Dan Arne & Olesen, Poul, 1 Mar 2002, In: BioTechniques. 32, 3, p. 536-8, 540

      Research output: Contribution to journal › Journal article › Research › peer-review

    93. Published

      The KCNQ1 potassium channel: from gene to physiological function.

      Jespersen, Thomas, Grunnet, Morten & Olesen, Søren-Peter, 2005, In: Physiology. 20, p. 408-16 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Published

      Urinary markers of nucleic acid oxidation increase with age, obesity and insulin resistance in Danish children and adolescents

      Jors, A., Lund, M. A. ,. V., Jespersen, Thomas, Hansen, Torben, Poulsen, Henrik Enghusen & Holm, Jens-Christian, 2020, In: Free Radical Biology and Medicine. 155, p. 81-86

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. Published

      Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization

      Jørgensen, S. T., Eriksen, H. N., Dausell, J., Jespersen, Thomas, Lambert, Ian Henry & Hoffmann, E. K., 2013, In: Cellular Physiology and Biochemistry. 31, 2-3, p. 366-378 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    96. Published

      Flecainide provocation reveals concealed brugada syndrome in a long QT syndrome family with a novel L1786Q mutation in SCN5A. SCN5A mutations associated with overlap phenotype of long QT syndrome type 3 and Brugada syndrome.

      Kanters, Jørgen K., Yuan, L., Hedley, P. L., Stoevring, B., Jons, C., Bloch Thomsen, P. E., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 6 Mar 2014, In: Circulation Journal. 78, 5, p. 1136-43 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    97. Published

      Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family

      Kanters, Jørgen K., Skibsbye, L., Hedley, P. L., Dembic, M., Liang, B., Hagen, C. M., Eschen, O., Grunnet, Morten, Christiansen, M. & Jespersen, Thomas, 2015, In: Scandinavian Journal of Clinical & Laboratory Investigation. 75, 8, p. 699-709 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    98. Published

      Antiarrhythmic effect of the Ca(2+)-activated K(+) (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation

      Kirchhoff, J. E., Diness, Jonas Goldin, Abildgaard, L., Sheykhzade, Majid, Grunnet, Morten & Jespersen, Thomas, 8 Oct 2016, In: Pfluegers Archiv. 468, 11, p. 1853–1863 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Published

      The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

      Kirchhoff, J. E., Skarsfeldt, M., Muthukumarasamy, K. M., Simó-Vicens, R., Bomholtz, Sofia Hammami, Abildgaard, L., Jespersen, Thomas, Sørensen, U. S., Grunnet, Morten, Bentzen, Bo Hjorth & Diness, Jonas Goldin, 2019, In: Frontiers in Pharmacology. 10, 13 p., 668.

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Published

      Synergistic antiarrhythmic effect of combining inhibition of Ca(2+)-activated K(+) (SK) channels and voltage-gated Na(+) channels in an isolated heart model of atrial fibrillation

      Kirchhoff, J. E., Goldin Diness, J., Sheykhzade, Majid, Grunnet, M. & Jespersen, Thomas, Feb 2015, In: Heart rhythm : the official journal of the Heart Rhythm Society. 12, 2, p. 409-18 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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