Steen Larsen

Steen Larsen

Associate Professor

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ORCID: 0000-0002-5170-4337

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  1. Published

    Impaired mitochondrial function in chronically ischemic human heart

    Stride, N., Larsen, Steen, Hey-Mogensen, M., Hansen, C. N., Prats Gavalda, Clara, Steinbrüchel, D., Køber, Lars Valeur & Dela, Flemming, 1 Jun 2013, In: American Journal of Physiology: Heart and Circulatory Physiology. 304, 11, p. H1407-14 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Increased intrinsic mitochondrial function in humans with mitochondrial haplogroup H

    Larsen, Steen, Díez-Sánchez, C., Rabøl, R., Ara, I., Dela, Flemming & Helge, Jørn Wulff, Feb 2014, In: Biochimica et Biophysica Acta - Bioenergetics. 1837, 2, p. 226-31 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Increased intrinsic mitochondrial respiratory capacity in skeletal muscle from rats with streptozotocin-induced hyperglycemia

    Larsen, Steen, Scheede-Bergdahl, C., Whitesell, T., Boushel, R. & Bergdahl, A., 2015, In: Physiological Reports. 3, 7, p. 1-10 10 p., e12467.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes

    Larsen, Steen, Stride, N., Hey-Mogensen, M., Hansen, C. N., Andersen, J. L., Madsbad, Sten, Worm, Dorte, Helge, Jørn Wulff & Dela, Flemming, 2011, In: Diabetologia. 54, 6, p. 1427-36 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Influence of age on leptin induced skeletal muscle signaling

    Guadalupe Grau, A., Larsen, Steen, Guerra, B., Calbet, J. A., Dela, Flemming & Helge, Jørn Wulff, 8 Mar 2014, In: Acta Physiologica. 211, 1, p. 214-228 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Influence of exercise amount and intensity on long-term weight loss maintenance and skeletal muscle mitochondrial ROS production in humans

    Larsen, Steen, Dandanell, S., Kristensen, K. B., Jorgensen, S. D., Dela, Flemming & Helge, Jørn Wulff, 2019, In: Applied Physiology, Nutrition and Metabolism. 44, 9, p. 958-964

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Influence of maximal fat oxidation on long-term weight loss maintenance in humans

    Dandanell, S., Husted, Karina Louise Skov, Amdisen, S., Vigelso, A., Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, Jul 2017, In: Journal of Applied Physiology. 123, 1, p. 267-274 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity

    Damgaard, Mads Vargas, Nielsen, Thomas Svava, Basse, A. L., Chubanava, Sabina, Trost, K., Moritz, Thomas, Dellinger, R. W., Larsen, Steen & Treebak, Jonas Thue, 2022, In: iScience. 25, 2, 21 p., 103863.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Is there plasticity in mitochondrial cristae density with endurance training?

    Larsen, Steen, Helge, Jørn Wulff & Dela, Flemming, 1 May 2017, In: Journal of Physiology. 595, 9, p. 2985-2985 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  10. Published

    LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction

    Christensen, Christa Lykke, Helge, Jørn Wulff, Krasnik, Allan, Kriegbaum, Margit, Rasmussen, Lene Juel, Hickson, Ian David, Liisberg, Kasper Bering, Oxlund, Bjarke, Bruun, B., Lau, Sofie Rosenlund, Olsen, M. N. A., Andersen, John Sahl, Heltberg, Andreas Søndergaard, Kuhlman, A. C. B., Morville, T. H., Dohlmann, T. L., Larsen, Steen & Dela, Flemming, 2016, In: Scandinavian Journal of Public Health. 44, 5, p. 534-539 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Low-Grade Inflammation Is Not Present in Former Obese Males but Adipose Tissue Macrophage Infiltration Persists

    Ara, I., Auerbach, P., Larsen, Steen, Mata, E., Stallknecht, Bente Merete, Ploug, Thorkil, Prats Gavalda, Clara & Helge, Jørn Wulff, 2020, In: Biomedicines. 8, 5, 10 p., 123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Maximal fat oxidation rate across the adult lifespan of trained women

    Dahlgaard Hansen, I. M., Wismann, J. F., Sahl, Ronni Eg, Frandsen, J., Hansen, Maria, Ingersen, Arthur, Schmücker, Malte, Modvig, J. L., Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2024, In: European Journal of Sport Science. 24, 1, p. 107-115 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Maximal fat oxidation rate is higher in fit women and unfit women with obesity, compared to normal weight unfit women

    Frandsen, J., Hansen, I. M. D., Wismann, J. F., Olsen, M. H., Brage-Andersen, M. R., Sahl, Ronni Eg, Hansen, M., Ingersen, Arthur, Modvig, J. L., Schmücker, M., brl298, brl298, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 11, p. E4389-E4399 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Metabolic effects of alternate-day fasting in males with obesity with or without type 2 diabetes

    Ingersen, Arthur, Helset, H. R., Calov, M., Chabanova, E., Harreskov, E. G., Jensen, C., Hansen, C. N., Prats Gavalda, Clara, Helge, Jørn Wulff, Larsen, Steen & Dela, Flemming, 2022, In: Frontiers in Physiology. 13, 1 p., 1061063.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. E-pub ahead of print

    Metabolic flexibility in postmenopausal women: Hormone replacement therapy is associated with higher mitochondrial content, respiratory capacity, and lower total fat mass

    Kleis-Olsen, Ann-Sofie Amalie, Farlov, J. E., Petersen, E. A., Schmücker, Malte, Flensted-Jensen, Mathias, Blom, Ida, Ingersen, Arthur, Hansen, M., Helge, Jørn Wulff, Dela, Flemming & Larsen, Steen, 2024, (E-pub ahead of print) In: Acta Physiologica.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Metabolomic Profile of Skeletal Muscle and Its Change Under a Mixed-Mode Exercise Intervention in Progressively Dysglycemic Subjects

    Szczerbinski, L., Golonko, A., Taylor, M., Puchta, U., Konopka, P., Paszko, A., Citko, A., Szczerbinski, K., Gorska, M., Zabielski, P., Błachnio-Zabielska, A., Larsen, Steen & Kretowski, A., 2021, In: Frontiers in Endocrinology. 12, 13 p., 778442.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration

    Larsen, Steen, Rabøl, R., Hansen, C. N., Madsbad, Sten, Helge, Jørn Wulff & Dela, Flemming, 2012, In: Diabetologia. 55, 2, p. 443-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Mitochondrial function in human skeletal muscle: Influence of age, physical fitness and insulin sensitivity

    Larsen, Steen, 2013

    Research output: Book/Report › Doctoral thesis › Research

  19. Published

    Mitochondrial adaptations to high intensity interval training in older females and males

    Chrois, K. M., Dohlmann, T. L., Sogaard, D., Hansen, Camilla Collin, Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2020, In: European Journal of Sport Science. 20, 1, p. 135-145

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Mitochondrial dysfunction in adults after out-of-hospital cardiac arrest

    Wiberg, S., Stride, N., Bro-Jeppesen, J., Holmberg, M. J., Kjærgaard, J., Larsen, Steen, Donnino, M. W., Hassager, Christian & Dela, Flemming, 2020, In: European Heart Journal: Acute Cardiovascular Care. 9, 4, p. S138–S144 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity

    Dall, M., Trammell, Sam, Asping, M., Hassing, Anna Skab, Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, Steen & Treebak, Jonas Thue, 2019, In: The Journal of Biological Chemistry. 294, 36, p. 13304-13326 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery

    Lund, M. T., Larsen, Steen, Hansen, M., Courraud, J., Floyd, A. K., Støckel, M., Helge, Jørn Wulff & Dela, Flemming, 1 May 2018, In: Acta Physiologica. 223, 1, p. 1-9 e13032.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Muscle-Saturated Bioactive Lipids Are Increased with Aging and Influenced by High-Intensity Interval Training

    Søgaard, D., Baranowski, M., Larsen, Steen, Taulo Lund, M., Munk Scheuer, C., Vestergaard Abildskov, C., Greve Dideriksen, S., Dela, Flemming & Helge, Jørn Wulff, 2019, In: International Journal of Molecular Sciences . 20, 5, 1240.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin resistant men

    Dollerup, O. L., Chubanava, Sabina, Agerholm, M., Søndergård, S. D., Altıntaş, Ali, Møller, A. B., Høyer, K. F., Ringgaard, S., Stødkilde-Jørgensen, H., Lavery, G. G., Barrès, Romain, Larsen, Steen, Prats Gavalda, Clara, Jessen, N. & Treebak, Jonas Thue, 2020, In: Journal of Physiology. 598, 4, p. 731-754

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Normal mitochondrial function and increased fat oxidation capacity in leg and arm muscles in obese humans

    Ara, I., Larsen, Steen, Stallknecht, Bente Merete, Guerra, B., Morales-Alamo, D., Andersen, J. L., Ponce-González, J. G., Guadalupe-Grau, A., Galbo, Henrik, Calbet, J. A. L. & Helge, Jørn Wulff, 2011, In: International Journal of Obesity. 35, 1, p. 99-108 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Peripheral blood mononuclear cells exhibit increased mitochondrial respiration after adjuvant chemo- and radiotherapy for early breast cancer

    Christensen, I. B., Abrahamsen, Marie-Louise Brødsgaard, Ribas, L., Buch-Larsen, K., Marina, D., Andersson, M., Larsen, Steen, Schwarz, Peter, Dela, Flemming & Gillberg, Linn, 2023, In: Cancer Medicine. 12, 16, p. 16985-16996 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Perturbations of NAD+ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle

    Andersen, M. A., Dall, M., Jensen, Benjamin Anderschou Holbech, Prats Gavalda, Clara, Madsen, S., Basse, A. L., Graae, A., Risis, S., Goldenbaum, J., Quistorff, B., Larsen, Steen, Vienberg, S. G. & Treebak, Jonas Thue, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 4, p. E377-E395 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Plasma free fatty acid concentration is closely tied to whole-body peak fat oxidation rate during repeated exercise

    Frandsen, J., Vest, S. D., Ritz, C., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Journal of Applied Physiology. 126, 6, p. 1563-1571 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Pre-ischemic succinate dehydrogenase inhibition is protective against ischemia-reperfusion injury in rat and human myocardium with and without diabetes mellitus: [Meeting Abstract]

    Jespersen, N. R., Hjortbak, M. V., Lassen, T. R., Stoettrup, N. B., Johnsen, J., Tonnesen, P. T., Larsen, Steen, Kimose, H. H. & Boetker, H. E., 2019, In: European Heart Journal. 40, S.1, p. 2101-2101 P3487 .

    Research output: Contribution to journal › Conference abstract in journal › Research

  30. Published

    Prolonged Endurance Exercise Increases Macrophage Content and Mitochondrial Respiration in Adipose Tissue in Trained Men

    Sahl, Ronni Eg, Patsi, Ioanna, Hansen, Mikkel Thunestvedt, Rømer, Tue, Frandsen, J., Rasmusen, Hanne K., Ingersen, Arthur, Poulsen, Steen Seier, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2024, In: The Journal of clinical endocrinology and metabolism. 109, 2, p. e799-e808 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Regional anatomic differences in skeletal muscle mitochondrial respiration in type 2 diabetes and obesity

    Rabøl, R., Larsen, Steen, Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R. C., Haugaard, Steen Bendix, Andersen, J. L., Madsbad, Sten & Dela, Flemming, 1 Feb 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 857-63 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Reply

    Larsen, Steen, Stride, N., Hey-Mogensen, M., Hansen, C. N., Bang, L. E., Bundgård, Henning, Nielsen, L. B., Helge, Jørn Wulff & Dela, Flemming, 11 Jun 2013, In: Journal of the American College of Cardiology. 61, 23, p. 2393 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  33. Published

    Reply

    Larsen, Steen, Hansen, C. N., Helge, Jørn Wulff & Dela, Flemming, 16 Jul 2013, In: Journal of the American College of Cardiology. 62, 3, p. 257-8 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  34. Published

    Reply to Dutheil et al

    Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Journal of applied physiology (Bethesda, Md. : 1985). 129, 1, 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  35. Published

    Simvastatin improves mitochondrial respiration in peripheral blood cells

    Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Six weeks of high intensity cycle training reduces H2O2 emission and increases antioxidant protein levels in obese adults with risk factors for type 2 diabetes

    Flensted-Jensen, Mathias, Gram, M., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2021, In: Free Radical Biology & Medicine. 173, p. 1-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Statin Treatment Decreases Mitochondrial Respiration But Muscle Coenzyme Q10 Levels Are Unaltered: The LIFESTAT Study

    Dohlmann, T. L., Morville, T., Kuhlman, A. B., Chrøis, K. M., Helge, Jørn Wulff, Dela, Flemming & Larsen, Steen, Jul 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2501–2508

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    The Effect of Exercise Training on Muscle Coenzyme Q10 in Symptomatic and Asymptomatic Statin Users

    Allard, N. A. E., Orlando, P., Janssen, L., Larsen, Steen, Tiano, L., Hopman, M. T. E. & Timmers, S., 2023, In: JACC: Basic to Translational Science. 8, 12, p. 1592-1594

    Research output: Contribution to journal › Letter › Research › peer-review

  39. Published

    The effect of 8 weeks of physical training on muscle performance and maximal fat oxidation rates in patients treated with simvastatin and coenzyme Q10 supplementation

    Kuhlman, A. B., Mikkelsen, L. B., Regnersgaard, S., Heinrichsen, S., Nielsen, F. H., Frandsen, J., Orlando, P., Silvestri, S., Larsen, Steen, Helge, Jørn Wulff & Dela, Flemming, 2022, In: Journal of Physiology. 600, 3, p. 569-581 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The effect of high-intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue

    Larsen, Steen, Danielsen, J. H., Søndergård, S. D., Søgaard, D., Vigelsoe, A., Dybboe, R., Skaaby, Stinna, Dela, Flemming & Helge, Jørn Wulff, Feb 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, 1, p. e59-e69

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    The influence of age and aerobic fitness: effects on mitochondrial respiration in skeletal muscle

    Hey-Mogensen, M., Rabøl, R., Stride, N., Helge, Jørn Wulff, Dela, Flemming & Larsen, Steen, 2012, In: Acta Physiologica (Print). 205, 3, p. 423-32 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    The influence of age, sex and cardiorespiratory fitness on maximal fat oxidation rate

    Frandsen, J., Amaro-Gahete, F. J., Landgrebe, A., Dela, Flemming, Ruiz, J. R., Helge, Jørn Wulff & Larsen, Steen, 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 10, p. 1241-1247

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The relationship between peak fat oxidation and prolonged double-poling endurance exercise performance

    Rømer, Tue, Hansen, Mikkel Thunestvedt, Frandsen, J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Scandinavian Journal of Medicine & Science in Sports. 30, 11, p. 2044-2056

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The response of mitochondrial respiration and quantity in skeletal muscle and adipose tissue to exercise in humans with prediabetes

    Szczerbinski, L., Taylor, M. A., Puchta, U., Konopka, P., Paszko, A., Citko, A., Szczerbinski, K., Goscik, J., Gorska, M., Larsen, Steen & Kretowski, A., 2021, In: Cells. 10, 11, 3013.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging

    Frandsen, J., Beck, T., Langkilde, C. H., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2021, In: European Journal of Sport Science. 21, 1, p. 69-76

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure

    Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice

    Kristensen, Jonas Møller, Larsen, Steen, Helge, Jørn Wulff, Dela, Flemming & Wojtaszewski, Jørgen F P, 2013, In: P L o S One. 8, 1, 10 p., e53533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies

    Sahl, Ronni Eg, Morville, T., Kraunsøe, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 1 Sep 2018, In: Analytical Biochemistry. 556, p. 119-124 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 4969436