Steen Larsen
Associate Professor
Exercise and Muscle
Blegdamsvej 3
2200 København N.
Member of:
Web: Center for Healthy Aging
Web Track 3: Individualized health
- Published
Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies
Sahl, Ronni Eg, Morville, T., Kraunsøe, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 1 Sep 2018, In: Analytical Biochemistry. 556, p. 119-124 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
Kristensen, Jonas Møller, Larsen, Steen, Helge, Jørn Wulff, Dela, Flemming & Wojtaszewski, Jørgen F P, 2013, In: P L o S One. 8, 1, 10 p., e53533.Research output: Contribution to journal › Journal article › Research › peer-review
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Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure
Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging
Frandsen, J., Beck, T., Langkilde, C. H., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2021, In: European Journal of Sport Science. 21, 1, p. 69-76Research output: Contribution to journal › Journal article › Research › peer-review
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The response of mitochondrial respiration and quantity in skeletal muscle and adipose tissue to exercise in humans with prediabetes
Szczerbinski, L., Taylor, M. A., Puchta, U., Konopka, P., Paszko, A., Citko, A., Szczerbinski, K., Goscik, J., Gorska, M., Larsen, Steen & Kretowski, A., 2021, In: Cells. 10, 11, 3013.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The relationship between peak fat oxidation and prolonged double-poling endurance exercise performance
Rømer, Tue, Hansen, Mikkel Thunestvedt, Frandsen, J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Scandinavian Journal of Medicine & Science in Sports. 30, 11, p. 2044-2056Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of age, sex and cardiorespiratory fitness on maximal fat oxidation rate
Frandsen, J., Amaro-Gahete, F. J., Landgrebe, A., Dela, Flemming, Ruiz, J. R., Helge, Jørn Wulff & Larsen, Steen, 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 10, p. 1241-1247Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of age and aerobic fitness: effects on mitochondrial respiration in skeletal muscle
Hey-Mogensen, M., Rabøl, R., Stride, N., Helge, Jørn Wulff, Dela, Flemming & Larsen, Steen, 2012, In: Acta Physiologica (Print). 205, 3, p. 423-32 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of high-intensity training on mitochondrial fat oxidation in skeletal muscle and subcutaneous adipose tissue
Larsen, Steen, Danielsen, J. H., Søndergård, S. D., Søgaard, D., Vigelsoe, A., Dybboe, R., Skaaby, Stinna, Dela, Flemming & Helge, Jørn Wulff, Feb 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, 1, p. e59-e69Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of 8 weeks of physical training on muscle performance and maximal fat oxidation rates in patients treated with simvastatin and coenzyme Q10 supplementation
Kuhlman, A. B., Mikkelsen, L. B., Regnersgaard, S., Heinrichsen, S., Nielsen, F. H., Frandsen, J., Orlando, P., Silvestri, S., Larsen, Steen, Helge, Jørn Wulff & Dela, Flemming, 2022, In: Journal of Physiology. 600, 3, p. 569-581 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Exercise Training on Muscle Coenzyme Q10 in Symptomatic and Asymptomatic Statin Users
Allard, N. A. E., Orlando, P., Janssen, L., Larsen, Steen, Tiano, L., Hopman, M. T. E. & Timmers, S., 2023, In: JACC: Basic to Translational Science. 8, 12, p. 1592-1594Research output: Contribution to journal › Letter › Research › peer-review
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Statin Treatment Decreases Mitochondrial Respiration But Muscle Coenzyme Q10 Levels Are Unaltered: The LIFESTAT Study
Dohlmann, T. L., Morville, T., Kuhlman, A. B., Chrøis, K. M., Helge, Jørn Wulff, Dela, Flemming & Larsen, Steen, Jul 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2501–2508Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Six weeks of high intensity cycle training reduces H2O2 emission and increases antioxidant protein levels in obese adults with risk factors for type 2 diabetes
Flensted-Jensen, Mathias, Gram, M., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2021, In: Free Radical Biology & Medicine. 173, p. 1-6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simvastatin improves mitochondrial respiration in peripheral blood cells
Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to Dutheil et al
Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Journal of applied physiology (Bethesda, Md. : 1985). 129, 1, 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Reply
Larsen, Steen, Stride, N., Hey-Mogensen, M., Hansen, C. N., Bang, L. E., Bundgård, Henning, Nielsen, L. B., Helge, Jørn Wulff & Dela, Flemming, 11 Jun 2013, In: Journal of the American College of Cardiology. 61, 23, p. 2393 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Reply
Larsen, Steen, Hansen, C. N., Helge, Jørn Wulff & Dela, Flemming, 16 Jul 2013, In: Journal of the American College of Cardiology. 62, 3, p. 257-8 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Regional anatomic differences in skeletal muscle mitochondrial respiration in type 2 diabetes and obesity
Rabøl, R., Larsen, Steen, Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R. C., Haugaard, Steen Bendix, Andersen, J. L., Madsbad, Sten & Dela, Flemming, 1 Feb 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 857-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged Endurance Exercise Increases Macrophage Content and Mitochondrial Respiration in Adipose Tissue in Trained Men
Sahl, Ronni Eg, Patsi, Ioanna, Hansen, Mikkel Thunestvedt, Rømer, Tue, Frandsen, J., Rasmusen, Hanne K., Ingersen, Arthur, Poulsen, Steen Seier, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2024, In: The Journal of clinical endocrinology and metabolism. 109, 2, p. e799-e808 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pre-ischemic succinate dehydrogenase inhibition is protective against ischemia-reperfusion injury in rat and human myocardium with and without diabetes mellitus: [Meeting Abstract]
Jespersen, N. R., Hjortbak, M. V., Lassen, T. R., Stoettrup, N. B., Johnsen, J., Tonnesen, P. T., Larsen, Steen, Kimose, H. H. & Boetker, H. E., 2019, In: European Heart Journal. 40, S.1, p. 2101-2101 P3487 .Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Plasma free fatty acid concentration is closely tied to whole-body peak fat oxidation rate during repeated exercise
Frandsen, J., Vest, S. D., Ritz, C., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Journal of Applied Physiology. 126, 6, p. 1563-1571 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perturbations of NAD+ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle
Andersen, M. A., Dall, M., Jensen, Benjamin Anderschou Holbech, Prats Gavalda, Clara, Madsen, S., Basse, A. L., Graae, A., Risis, S., Goldenbaum, J., Quistorff, B., Larsen, Steen, Vienberg, S. G. & Treebak, Jonas Thue, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 4, p. E377-E395 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peripheral blood mononuclear cells exhibit increased mitochondrial respiration after adjuvant chemo- and radiotherapy for early breast cancer
Christensen, I. B., Abrahamsen, Marie-Louise Brødsgaard, Ribas, L., Buch-Larsen, K., Marina, D., Andersson, M., Larsen, Steen, Schwarz, Peter, Dela, Flemming & Gillberg, Linn, 2023, In: Cancer Medicine. 12, 16, p. 16985-16996 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal mitochondrial function and increased fat oxidation capacity in leg and arm muscles in obese humans
Ara, I., Larsen, Steen, Stallknecht, Bente Merete, Guerra, B., Morales-Alamo, D., Andersen, J. L., Ponce-González, J. G., Guadalupe-Grau, A., Galbo, Henrik, Calbet, J. A. L. & Helge, Jørn Wulff, 2011, In: International Journal of Obesity. 35, 1, p. 99-108 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin resistant men
Dollerup, O. L., Chubanava, Sabina, Agerholm, M., Søndergård, S. D., Altıntaş, Ali, Møller, A. B., Høyer, K. F., Ringgaard, S., Stødkilde-Jørgensen, H., Lavery, G. G., Barrès, Romain, Larsen, Steen, Prats Gavalda, Clara, Jessen, N. & Treebak, Jonas Thue, 2020, In: Journal of Physiology. 598, 4, p. 731-754Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle-Saturated Bioactive Lipids Are Increased with Aging and Influenced by High-Intensity Interval Training
Søgaard, D., Baranowski, M., Larsen, Steen, Taulo Lund, M., Munk Scheuer, C., Vestergaard Abildskov, C., Greve Dideriksen, S., Dela, Flemming & Helge, Jørn Wulff, 2019, In: International Journal of Molecular Sciences . 20, 5, 1240.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery
Lund, M. T., Larsen, Steen, Hansen, M., Courraud, J., Floyd, A. K., Støckel, M., Helge, Jørn Wulff & Dela, Flemming, 1 May 2018, In: Acta Physiologica. 223, 1, p. 1-9 e13032.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity
Dall, M., Trammell, Sam, Asping, M., Hassing, Anna Skab, Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, Steen & Treebak, Jonas Thue, 2019, In: The Journal of Biological Chemistry. 294, 36, p. 13304-13326 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial dysfunction in adults after out-of-hospital cardiac arrest
Wiberg, S., Stride, N., Bro-Jeppesen, J., Holmberg, M. J., Kjærgaard, J., Larsen, Steen, Donnino, M. W., Hassager, Christian & Dela, Flemming, 2020, In: European Heart Journal: Acute Cardiovascular Care. 9, 4, p. S138–S144 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mitochondrial adaptations to high intensity interval training in older females and males
Chrois, K. M., Dohlmann, T. L., Sogaard, D., Hansen, Camilla Collin, Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2020, In: European Journal of Sport Science. 20, 1, p. 135-145Research output: Contribution to journal › Journal article › Research › peer-review
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Mitochondrial function in human skeletal muscle: Influence of age, physical fitness and insulin sensitivity
Larsen, Steen, 2013Research output: Book/Report › Doctoral thesis › Research
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Metformin-treated patients with type 2 diabetes have normal mitochondrial complex I respiration
Larsen, Steen, Rabøl, R., Hansen, C. N., Madsbad, Sten, Helge, Jørn Wulff & Dela, Flemming, 2012, In: Diabetologia. 55, 2, p. 443-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolomic Profile of Skeletal Muscle and Its Change Under a Mixed-Mode Exercise Intervention in Progressively Dysglycemic Subjects
Szczerbinski, L., Golonko, A., Taylor, M., Puchta, U., Konopka, P., Paszko, A., Citko, A., Szczerbinski, K., Gorska, M., Zabielski, P., Błachnio-Zabielska, A., Larsen, Steen & Kretowski, A., 2021, In: Frontiers in Endocrinology. 12, 13 p., 778442.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Metabolic flexibility in postmenopausal women: Hormone replacement therapy is associated with higher mitochondrial content, respiratory capacity, and lower total fat mass
Kleis-Olsen, Ann-Sofie Amalie, Farlov, J. E., Petersen, E. A., Schmücker, Malte, Flensted-Jensen, Mathias, Blom, Ida, Ingersen, Arthur, Hansen, M., Helge, Jørn Wulff, Dela, Flemming & Larsen, Steen, 2024, (E-pub ahead of print) In: Acta Physiologica.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic effects of alternate-day fasting in males with obesity with or without type 2 diabetes
Ingersen, Arthur, Helset, H. R., Calov, M., Chabanova, E., Harreskov, E. G., Jensen, C., Hansen, C. N., Prats Gavalda, Clara, Helge, Jørn Wulff, Larsen, Steen & Dela, Flemming, 2022, In: Frontiers in Physiology. 13, 1 p., 1061063.Research output: Contribution to journal › Journal article › Research › peer-review
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Maximal fat oxidation rate is higher in fit women and unfit women with obesity, compared to normal weight unfit women
Frandsen, J., Hansen, I. M. D., Wismann, J. F., Olsen, M. H., Brage-Andersen, M. R., Sahl, Ronni Eg, Hansen, M., Ingersen, Arthur, Modvig, J. L., Schmücker, M., brl298, brl298, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 11, p. E4389-E4399 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maximal fat oxidation rate across the adult lifespan of trained women
Dahlgaard Hansen, I. M., Wismann, J. F., Sahl, Ronni Eg, Frandsen, J., Hansen, Maria, Ingersen, Arthur, Schmücker, Malte, Modvig, J. L., Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2024, In: European Journal of Sport Science. 24, 1, p. 107-115 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-Grade Inflammation Is Not Present in Former Obese Males but Adipose Tissue Macrophage Infiltration Persists
Ara, I., Auerbach, P., Larsen, Steen, Mata, E., Stallknecht, Bente Merete, Ploug, Thorkil, Prats Gavalda, Clara & Helge, Jørn Wulff, 2020, In: Biomedicines. 8, 5, 10 p., 123.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction
Christensen, Christa Lykke, Helge, Jørn Wulff, Krasnik, Allan, Kriegbaum, Margit, Rasmussen, Lene Juel, Hickson, Ian David, Liisberg, Kasper Bering, Oxlund, Bjarke, Bruun, B., Lau, Sofie Rosenlund, Olsen, M. N. A., Andersen, John Sahl, Heltberg, Andreas Søndergaard, Kuhlman, A. C. B., Morville, T. H., Dohlmann, T. L., Larsen, Steen & Dela, Flemming, 2016, In: Scandinavian Journal of Public Health. 44, 5, p. 534-539 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is there plasticity in mitochondrial cristae density with endurance training?
Larsen, Steen, Helge, Jørn Wulff & Dela, Flemming, 1 May 2017, In: Journal of Physiology. 595, 9, p. 2985-2985 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity
Damgaard, Mads Vargas, Nielsen, Thomas Svava, Basse, A. L., Chubanava, Sabina, Trost, K., Moritz, Thomas, Dellinger, R. W., Larsen, Steen & Treebak, Jonas Thue, 2022, In: iScience. 25, 2, 21 p., 103863.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of maximal fat oxidation on long-term weight loss maintenance in humans
Dandanell, S., Husted, Karina Louise Skov, Amdisen, S., Vigelso, A., Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, Jul 2017, In: Journal of Applied Physiology. 123, 1, p. 267-274 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of exercise amount and intensity on long-term weight loss maintenance and skeletal muscle mitochondrial ROS production in humans
Larsen, Steen, Dandanell, S., Kristensen, K. B., Jorgensen, S. D., Dela, Flemming & Helge, Jørn Wulff, 2019, In: Applied Physiology, Nutrition and Metabolism. 44, 9, p. 958-964Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of age on leptin induced skeletal muscle signaling
Guadalupe Grau, A., Larsen, Steen, Guerra, B., Calbet, J. A., Dela, Flemming & Helge, Jørn Wulff, 8 Mar 2014, In: Acta Physiologica. 211, 1, p. 214-228 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes
Larsen, Steen, Stride, N., Hey-Mogensen, M., Hansen, C. N., Andersen, J. L., Madsbad, Sten, Worm, Dorte, Helge, Jørn Wulff & Dela, Flemming, 2011, In: Diabetologia. 54, 6, p. 1427-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased intrinsic mitochondrial respiratory capacity in skeletal muscle from rats with streptozotocin-induced hyperglycemia
Larsen, Steen, Scheede-Bergdahl, C., Whitesell, T., Boushel, R. & Bergdahl, A., 2015, In: Physiological Reports. 3, 7, p. 1-10 10 p., e12467.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased intrinsic mitochondrial function in humans with mitochondrial haplogroup H
Larsen, Steen, Díez-Sánchez, C., Rabøl, R., Ara, I., Dela, Flemming & Helge, Jørn Wulff, Feb 2014, In: Biochimica et Biophysica Acta - Bioenergetics. 1837, 2, p. 226-31 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired mitochondrial function in chronically ischemic human heart
Stride, N. O., Larsen, Steen, Hey-Mogensen, M., Hansen, C., Prats, C., Steinbrüchel, D., Køber, Lars Valeur & Dela, Flemming, 2013, In: A J P: Heart and Circulatory Physiology (Online). 304, 11, p. H1407-H1414 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired mitochondrial function in chronically ischemic human heart
Stride, N., Larsen, Steen, Hey-Mogensen, M., Hansen, C. N., Prats Gavalda, Clara, Steinbrüchel, D., Køber, Lars Valeur & Dela, Flemming, 1 Jun 2013, In: American Journal of Physiology: Heart and Circulatory Physiology. 304, 11, p. H1407-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-intensity interval training improves insulin sensitivity in older individuals
Søgaard, D., Lund, M. T., Scheuer, C. M., Dehlbaek, M. S., Dideriksen, S. G., Abildskov, C. V., Christensen, K. K., Dohlmann, T. L., Larsen, Steen, Vigelsø, A. H., Dela, Flemming & Helge, Jørn Wulff, Apr 2018, In: Acta Physiologica (Print). 222, 4, e13009.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4969436
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Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
575
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LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
221
downloads
Four days of bed rest increases intrinsic mitochondrial respiratory capacity in young healthy males
Research output: Contribution to journal › Journal article › Research › peer-review
Published