Michael Jonathan Davies
Michael Jonathan Davies

Professor


  1. 1994
  2. Published

    A hydrogen-donating monohydroxamate scavenges ferryl myoglobin radicals

    Cooper, C. E., Green, E. S., Rice-Evans, C. A., Davies, Michael Jonathan & Wrigglesworth, J. M., Apr 1994, In : Free Radical Research. 20, 4, p. 219-27 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 1995
  4. Published

    Reaction of ferric leghemoglobin with H2O2: formation of heme-protein cross-links and dimeric species

    Moreau, S., Davies, Michael Jonathan & Puppo, A., 16 Aug 1995, In : Biochimica et biophysica acta. 1251, 1, p. 17-22 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 1996
  6. Published

    Xanthine oxidase activity and free radical generation in patients with sepsis syndrome

    Galley, H. F., Davies, Michael Jonathan & Webster, N. R., 1996, In : Critical Care Medicine. 24, 10, p. 1649-53 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Effect of propofol and thiopentone on free radical mediated oxidative stress of the erythrocyte

    Murphy, P. G., Davies, Michael Jonathan, Columb, M. O. & Stratford, N., Apr 1996, In : British Journal of Anaesthesia. 76, 4, p. 536-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Novel monohydroxamate drugs attenuate myocardial reperfusion-induced arrhythmias

    Collis, C. S., Rice-Evans, C. & Davies, Michael Jonathan, Apr 1996, In : International Journal of Biochemistry & Cell Biology. 28, 4, p. 405-13 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Benzoyl peroxide-induced damage to DNA and its components: direct evidence for the generation of base adducts, sugar radicals, and strand breaks

    Hazlewood, C. & Davies, Michael Jonathan, 1 Aug 1996, In : Archives of Biochemistry and Biophysics. 332, 1, p. 79-91 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Protein and peptide alkoxyl radicals can give rise to C-terminal decarboxylation and backbone cleavage

    Davies, Michael Jonathan, 1 Dec 1996, In : Archives of Biochemistry and Biophysics. 336, 1, p. 163-72 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Leghemoglobin-derived radicals. Evidence for multiple protein-derived radicals and the initiation of peribacteroid membrane damage

    Moreau, S., Davies, Michael Jonathan, Mathieu, C., Hérouart, D. & Puppo, A., 20 Dec 1996, In : The Journal of Biological Chemistry. 271, 51, p. 32557-62 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 1997
  13. Published

    Biochemistry and pathology of radical-mediated protein oxidation

    Dean, R. T., Fu, S., Stocker, R. & Davies, Michael Jonathan, 1997, In : Biochemical Journal. 324 ( Pt 1), p. 1-18 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Oxidative damage to collagen and related substrates by metal ion/hydrogen peroxide systems: random attack or site-specific damage?

    Hawkins, C. L. & Davies, Michael Jonathan, 27 Feb 1997, In : B B A - Reviews on Cancer. 1360, 1, p. 84-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Absence of synproportionation between oxy and ferryl leghemoglobin. off

    Mathieu, C., Swaraj, K., Davies, Michael Jonathan, Trinchant, J. C. & Puppo, A., Aug 1997, In : Free Radical Research. 27, 2, p. 165-71 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    A kinetic and ESR investigation of iron(II) oxalate oxidation by hydrogen peroxide and dioxygen as a source of hydroxyl radicals

    Park, J. S., Wood, P. M., Davies, Michael Jonathan, Gilbert, B. C. & Whitwood, A. C., Nov 1997, In : Free Radical Research. 27, 5, p. 447-58 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 1998
  18. Published

    Direct detection of radicals in intact soybean nodules: presence of nitric oxide-leghemoglobin complexes

    Mathieu, C., Moreau, S., Frendo, P., Puppo, A. & Davies, Michael Jonathan, 1998, In : Free Radical Biology & Medicine. 24, 7-8, p. 1242-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Oxidation and antioxidation of human low-density lipoprotein and plasma exposed to 3-morpholinosydnonimine and reagent peroxynitrite

    Thomas, S. R., Davies, Michael Jonathan & Stocker, R., 1998, In : Chemical Research in Toxicology. 11, 5, p. 484-94 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Protein hydroperoxides and carbonyl groups generated by porphyrin-induced photo-oxidation of bovine serum albumin

    Silvester, J. A., Timmins, G. S. & Davies, Michael Jonathan, 15 Feb 1998, In : Archives of Biochemistry and Biophysics. 350, 2, p. 249-58 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Photodynamically generated bovine serum albumin radicals: evidence for damage transfer and oxidation at cysteine and tryptophan residues

    Silvester, J. A., Timmins, G. S. & Davies, Michael Jonathan, 15 Mar 1998, In : Free Radical Biology & Medicine. 24, 5, p. 754-66 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The protein oxidation product 3,4-dihydroxyphenylalanine (DOPA) mediates oxidative DNA damage

    Morin, B., Davies, Michael Jonathan & Dean, R. T., 15 Mar 1998, In : Biochemical Journal. 330 ( Pt 3), p. 1059-67 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Degradation of hyaluronic acid, poly- and monosaccharides, and model compounds by hypochlorite: evidence for radical intermediates and fragmentation

    Hawkins, C. L. & Davies, Michael Jonathan, Jun 1998, In : Free Radical Biology & Medicine. 24, 9, p. 1396-410 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation

    Hawkins, C. L. & Davies, Michael Jonathan, 15 Jun 1998, In : Biochemical Journal. 332 ( Pt 3), p. 617-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque

    Fu, S., Davies, Michael Jonathan, Stocker, R. & Dean, R. T., 1 Aug 1998, In : Biochemical Journal. 333 ( Pt 3), p. 519-25 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The cytoplasmic Cu,Zn superoxide dismutase of saccharomyces cerevisiae is required for resistance to freeze-thaw stress. Generation of free radicals during freezing and thawing

    Park, J. I., Grant, C. M., Davies, Michael Jonathan & Dawes, I. W., 4 Sep 1998, In : The Journal of Biological Chemistry. 273, 36, p. 22921-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    3-Hydroxylysine, a potential marker for studying radical-induced protein oxidation

    Morin, B., Bubb, W. A., Davies, Michael Jonathan, Dean, R. T. & Fu, S., Nov 1998, In : Chemical Research in Toxicology. 11, 11, p. 1265-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 1999
  29. Published

    Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins

    Hazell, L. J., Davies, Michael Jonathan & Stocker, R., 1999, In : Biochemical Journal. 339 ( Pt 3), p. 489-95 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Formation of long-lived radicals on proteins by radical transfer from heme enzymes--a common process?

    Ostdal, H., Andersen, H. J. & Davies, Michael Jonathan, 1 Feb 1999, In : Archives of Biochemistry and Biophysics. 362, 1, p. 105-12 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Myoglobin-induced oxidative damage: evidence for radical transfer from oxidized myoglobin to other proteins and antioxidants

    Irwin, J. A., Ostdal, H. & Davies, Michael Jonathan, 1 Feb 1999, In : Archives of Biochemistry and Biophysics. 362, 1, p. 94-104 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation

    Hawkins, C. L. & Davies, Michael Jonathan, 1 Jun 1999, In : Biochemical Journal. 340 ( Pt 2), p. 539-48 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Histone H1- and other protein- and amino acid-hydroperoxides can give rise to free radicals which oxidize DNA

    Luxford, C., Morin, B., Dean, R. T. & Davies, Michael Jonathan, 15 Nov 1999, In : Biochemical Journal. 344 Pt 1, p. 125-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Lipid oxidation in human low-density lipoprotein induced by metmyoglobin/H2O2: involvement of alpha-tocopheroxyl and phosphatidylcholine alkoxyl radicals

    Witting, P. K., Willhite, C. A., Davies, Michael Jonathan & Stocker, R., Dec 1999, In : Chemical Research in Toxicology. 12, 12, p. 1173-81 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Stable markers of oxidant damage to proteins and their application in the study of human disease

    Davies, Michael Jonathan, Fu, S., Wang, H. & Dean, R. T., Dec 1999, In : Free Radical Biology & Medicine. 27, 11-12, p. 1151-63 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. 2000
  37. Published

    An investigation into the genotoxic species generated during reduction of chromium(VI) by catechol(amine)s

    Pattison, D. I., Lay, P. A. & Davies, Michael Jonathan, 2000, In : Redox Report (Online). 5, 2-3, p. 130-2 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Hypochlorite-induced damage to red blood cells: evidence for the formation of nitrogen-centred radicals

    Hawkins, C. L. & Davies, Michael Jonathan, 2000, In : Redox Report (Online). 5, 1, p. 57-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Singlet oxygen-mediated protein oxidation: evidence for the formation of reactive peroxides

    Wright, A., Hawkins, C. L. & Davies, Michael Jonathan, 2000, In : Redox Report (Online). 5, 2-3, p. 159-61 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Formation of hydroxyl radicals in the human lens is related to the severity of nuclear cataract

    Garner, B., Davies, Michael Jonathan & Truscott, R. J., Jan 2000, In : Experimental Eye Research. 70, 1, p. 81-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    EPR studies of chromium(V) intermediates generated via reduction of chromium(VI) by DOPA and related catecholamines: potential role for oxidized amino acids in chromium-induced cancers

    Pattison, D. I., Lay, P. A. & Davies, Michael Jonathan, 26 Jun 2000, In : Inorganic Chemistry. 39, 13, p. 2729-39 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Radicals derived from histone hydroperoxides damage nucleobases in RNA and DNA

    Luxford, C., Dean, R. T. & Davies, Michael Jonathan, Jul 2000, In : Chemical Research in Toxicology. 13, 7, p. 665-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    beta-Scission of C-3 (beta-carbon) alkoxyl radicals on peptides and proteins: a novel pathway which results in the formation of alpha-carbon radicals and the loss of amino acid side chains

    Headlam, H. A., Mortimer, A., Easton, C. J. & Davies, Michael Jonathan, Nov 2000, In : Chemical Research in Toxicology. 13, 11, p. 1087-95 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Hypochlorite-induced oxidation of thiols: formation of thiyl radicals and the role of sulfenyl chlorides as intermediates

    Davies, Michael Jonathan & Hawkins, C. L., Dec 2000, In : Free Radical Research. 33, 6, p. 719-29 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2001
  46. Published

    Absolute rate constants for the reaction of hypochlorous acid with protein side chains and peptide bonds

    Pattison, D. I. & Davies, Michael Jonathan, 2001, In : Chemical Research in Toxicology. 14, 10, p. 1453-64 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Chromium(VI) reduction by catechol(amine)s results in DNA cleavage in vitro: relevance to chromium genotoxicity

    Pattison, D. I., Davies, Michael Jonathan, Levina, A., Dixon, N. E. & Lay, P. A., 2001, In : Chemical Research in Toxicology. 14, 5, p. 500-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Photo-oxidation of proteins and its role in cataractogenesis

    Davies, Michael Jonathan & Truscott, R. J., 2001, In : Journal of Photochemistry and Photobiology, B: Biology. 63, 1-3, p. 114-25 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    An investigation of the chromium oxidation state of a monoanionic chromium tris(catecholate) complex by X-ray absorption and EPR spectroscopies

    Pattison, D. I., Levina, A., Davies, Michael Jonathan & Lay, P. A., 15 Jan 2001, In : Inorganic Chemistry. 40, 2, p. 214-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Generation and propagation of radical reactions on proteins

    Hawkins, C. L. & Davies, Michael Jonathan, 2 Apr 2001, In : B B A - Reviews on Cancer. 1504, 2-3, p. 196-219 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals

    Hawkins, C. L. & Davies, Michael Jonathan, Aug 2001, In : Chemical Research in Toxicology. 14, 8, p. 1071-81 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Protein oxidation and ageing

    Linton, S., Davies, Michael Jonathan & Dean, R. T., Sep 2001, In : Experimental Gerontology. 36, 9, p. 1503-18 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis

    Hawkins, C. L., Brown, B. E. & Davies, Michael Jonathan, 15 Nov 2001, In : Archives of Biochemistry and Biophysics. 395, 2, p. 137-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2002
  55. Published

    Analysis of aliphatic amino acid alcohols in oxidized proteins

    Morin, B., Fu, S., Wang, H., Davies, Michael Jonathan & Dean, R. T., 2002, In : Methods in molecular biology (Clifton, N.J.). 186, p. 101-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Induction of DNA damage by oxidised amino acids and proteins

    Luxford, C., Dean, R. T. & Davies, Michael Jonathan, 2002, In : Biogerontology. 3, 1-2, p. 95-102 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals

    Hawkins, Clare Louise & Davies, Michael Jonathan, Jan 2002, In : Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins

    Hawkins, Clare Louise, Rees, M. D. & Davies, Michael Jonathan, 2 Jan 2002, In : FEBS letters. 510, 1-2, p. 41-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Inhibition of glyceraldehyde-3-phosphate dehydrogenase by peptide and protein peroxides generated by singlet oxygen attack

    Morgan, P. E., Dean, R. T. & Davies, Michael Jonathan, Apr 2002, In : European Journal of Biochemistry. 269, 7, p. 1916-25 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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