Mette Rosenkilde

Mette Rosenkilde

Professor

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    ORCID: 0000-0001-9600-3254

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    1. Published

      Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity

      Rosenkilde, Mette, Benned-Jensen, T., Holst, Peter Johannes, Kledal, T. N., Lüttichau, H. R., Larsen, J. K., Christensen, Jan Pravsgaard, Schwartz, Thue W. & Andersen, H., 2006, In: Journal of Biological Chemistry. 281, 19, p. 13199-208 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Molecular properties and therapeutic targeting of the ebv-encoded receptor bilf1

      Knerr, J. M., Kledal, T. N. & Rosenkilde, Mette, 2021, In: Cancers. 13, 16, 26 p., 4079.

      Research output: Contribution to journal › Review › Research › peer-review

    3. Published

      Molecular requirements for inhibition of the chemokine receptor CCR8--probe-dependent allosteric interactions

      Rummel, P. C., Arfelt, K. N., Baumann, L., Jenkins, T. J., Thiele, S., Lüttichau, H. R., Johnsen, A., Pease, J., Ghosh, S., Kolbeck, R. & Rosenkilde, Mette, Nov 2012, In: British Journal of Pharmacology. 167, 6, p. 1206-17 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Multiple Targets for Oxysterols in Their Regulation of the Immune System

      Reinmuth, L., Hsiao, C. C., Hamann, J., Rosenkilde, Mette & Mackrill, J., 2021, In: Cells. 10, 8, 27 p., 2078.

      Research output: Contribution to journal › Review › Research › peer-review

    5. Published

      Multistep Continuous-Flow Synthesis in Medicinal Chemistry: Discovery and Preliminary Structure-Activity Relationships of CCR8 Ligands

      Petersen, T. P., Mirsharghi, S., Rummel, P. C., Thiele, S., Rosenkilde, Mette, Ritzén, A. & Ulven, Trond, 8 Jul 2013, In: Chemistry: A European Journal. 19, 28, p. 9343-50 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Mutational Landscape of the Proglucagon-Derived Peptides

      Lindquist, Peter, Madsen, Jakob Sture, Bräuner, Hans, Rosenkilde, Mette & Hauser, Alexander Sebastian, 2021, In: Frontiers in Endocrinology. 12, 14 p., 698511.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry

      Hatse, S., Princen, K., Vermeire, K., Gerlach, L., Rosenkilde, Mette, Schwartz, Thue W., Bridger, G., De Clercq, E. & Schols, D., 2003, In: FEBS Letters. 546, 2-3, p. 300-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      N- and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor

      Hansen, L. S., wbf943, wbf943, Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 826-838 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction

      Gabe, M. B. N., Gasbjerg, Lærke Smidt, Gadgaard, S., Lindquist, Peter, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4473-4485

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Natural agonist enhancing bis-His zinc-site in transmembrane segment V of the tachykinin NK3 receptor

      Rosenkilde, Mette, Lucibello, M., Holst, Birgitte & Schwartz, Thue W., 1998, In: FEBS Letters. 439, 1-2, p. 35-40 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Natural carboxyterminal truncation of human CXCL10 attenuates glycosaminoglycan binding, CXCR3A signaling and lymphocyte chemotaxis, while retaining angiostatic activity

      Dillemans, L., Yu, K., De Zutter, A., Noppen, S., Gouwy, M., Berghmans, N., Verhallen, L., De Bondt, M., Vanbrabant, L., Brusselmans, S., Martens, E., Schols, D., Verschueren, P., Rosenkilde, Mette, Marques, P. E., Struyf, S. & Proost, P., 2024, In: Cell Communication and Signaling. 22, 1, 23 p., 94.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo

      Janssens, R., Mortier, A., Boff, D., Vanheule, V., Gouwy, M., Franck, C., Larsen, Olav, Rosenkilde, Mette, Damme, J. V., Amaral, F. A., Teixeira, M. M., Struyf, S. & Proost, P., 2016, In: OncoTarget. 7, 38, p. 62439-62459 21 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism

      Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Esser, N., Mongovin, S., Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Ceutz, F. R., Terzic, D., Mark, P. D., Plomgaard, Peter Stendahl, Goetze, Jens P. , Goossens, G. H., Blaak, E. E., Deacon, Carolyn F., Rosenkilde, Mette, Zraika, S., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Research. 5, 9, 15 p., bvab084.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Neprilysin inhibition increases plasma glucagon concentrations in humans with possible implications for hepatic amino acid metabolism

      Liver-Alpha-Cell Axis Grp, L. A. G., 2020, In: Diabetologia. 63, SUPPL 1, p. S72-S72 1 p., 144.

      Research output: Contribution to journal › Conference abstract in journal › Research

    15. Published

      Neuromedin U Does Not Act as a Decretin in Rats

      Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, Ida Marie, Mandrup-Poulsen, Thomas, Albrechtsen, Reidar, Rosenkilde, Mette, Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, In: Cell Metabolism. 29, 3, p. 719-726.e1-e5 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Novel Chemokine-Based Immunotoxins for Potent and Selective Targeting of Cytomegalovirus Infected Cells

      Spiess, Katja, Jeppesen, Mads Gravers, Malmgaard-Clausen, M., Krzywkowski, K., Kledal, T. N. & Rosenkilde, Mette, 2017, In: Journal of Immunology Research. 2017, 12 p., 4069260.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Oleoyl-lysophosphatidylinositol enhances glucagon-like peptide-1 secretion from enteroendocrine L-cells through GPR119

      Arifin, S. A., Paternoster, S., Carlessi, R., Casari, I., Ekberg, J. H., Maffucci, T., Newsholme, P., Rosenkilde, Mette & Falasca, M., 2018, In: B B A - Molecular and Cell Biology of Lipids. 1863, 9, p. 1132-1141

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats

      Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor

      Hassing, H. A., Engelstoft, M. S., Sichlau, R. M., Madsen, A. N., Rehfeld, Jens Frederik, Pedersen, Jens, Jones, R. M., Holst, Jens Juul, Schwartz, Thue W., Rosenkilde, Mette & Hansen, Harald S., 2016, In: BioFactors. 42, 6, p. 665-673

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Oxysterol-EBI2 signaling in immune regulation and viral infection

      Daugvilaite, V., Arfelt, K. N., Benned-Jensen, T., Sailer, A. W. & Rosenkilde, Mette, Jul 2014, In: European Journal of Immunology. 44, 7, p. 1904-12 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Partial functional complementation between human and mouse cytomegalovirus chemokine receptor homologues

      Farrell, H. E., Abraham, A. M., Cardin, R. D., wbf943, wbf943, Rosenkilde, Mette, Spiess, Katja, Jensen, T. H., Kledal, T. N. & Davis-Poynter, N., Jun 2011, In: Journal of Virology. 85, 12, p. 6091-5 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis

      Mavri, M., Glišić, S., Senćanski, M., Vrecl, M., Rosenkilde, Mette, Spiess, Katja & Kubale, V., 2023, In: Cellular and Molecular Biology Letters. 28, 1, 19 p., 14.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Peroxynitrite Exposure of CXCL12 Impairs Monocyte, Lymphocyte and Endothelial Cell Chemotaxis, Lymphocyte Extravasation in vivo and Anti-HIV-1 Activity

      Janssens, R., Boff, D., Ruytinx, P., Mortier, A., Vanheule, V., Larsen, Olav, Daugvilaite, V., Rosenkilde, Mette, Noppen, S., Liekens, S., Schols, D., De Meester, I., Opdenakker, G., Struyf, S., Teixeira, M. M., Amaral, F. A. & Proost, P., 2018, In: Frontiers in Immunology. 9, p. 1933

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Perspective: Implications of Ligand-Receptor Binding Kinetics for Therapeutic Targeting of G Protein-Coupled Receptors

      van der Velden, W. J. C., Heitman, L. H. & Rosenkilde, Mette, 2020, In: ACS Pharmacology & Translational Science. 3, 2, p. 179-189 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Pharmacokinetics of high-dose intravenous melatonin in humans

      Andersen, Lars Peter Kloster, Werner, M. U., Rosenkilde, Mette, Fenger, A. Q., Petersen, M. C., Rosenberg, Jacob & Gögenur, Ismail, Mar 2016, In: Journal of Clinical Pharmacology. 56, 3, p. 324-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 3361