Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Glucagon-like peptide-1 mediates the therapeutic actions of DPP-IV inhibitors

    Holst, Jens Juul & Deacon, Carolyn F., Apr 2005, In: Diabetologia. 48, 4, p. 612-5 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Searching for the physiological role of glucose-dependent insulinotropic polypeptide

    Holst, Jens Juul, Windeløv, Johanne Agerlin, Boer, G. A., Pedersen, Jens, Svendsen, B., Christensen, M., Torekov, Signe Sørensen, Asmar, M., Hartmann, Bolette & Nissen, A., 1 Apr 2016, In: Journal of Diabetes Investigation. 7, S1, p. 8-12 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Glucagon 100 years. Important, but still enigmatic

    Holst, Jens Juul, 2023, In: Peptides. 161, 6 p., 170942.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Glucagon-like peptide-1 (GLP-1) - A newly discovered Gl Hormone. Review.

    Holst, Jens Juul, 1994, In: Today in Medicine. Gastroenterology. 107, p. 1848-1855

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Posttranslational processing of proglucagon and postsecretory fate of proglucagon products.

    Holst, Jens Juul, Ørskov, C., Hartmann, B. & Deacon, Carolyn F., 1997, The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel: Karger, p. 24-48

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  6. Published

    Chap.10. Degradation of glucagons

    Holst, Jens Juul, 1991, Degradation of Bioactive Substances: Physiology and Pathophysiology. Boca Raton, Florida: CRC Press, p. 167-180

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  7. Published

    Actions of glucagon-like peptide-1 receptor ligands in the gut

    Holst, Jens Juul, Andersen, Daniel Bjørklund & Grunddal, Kaare Villum, 2022, In: British Journal of Pharmacology. 179, 4, p. 727-742

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Roles of the Gut in Glucose Homeostasis

    Holst, Jens Juul, Gribble, F., Horowitz, M. & Rayner, C. K., Jun 2016, In: Diabetes Care. 39, 6, p. 884-92 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    GLP-1 receptor agonists: targeting both hyperglycaemia and disease processes in diabetes

    Holst, Jens Juul & Seino, Y., 2009, In: Diabetes Research and Clinical Practice. 85, 1, p. 1-3 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Semaglutide seems to be more effective the other GLP-1Ras

    Holst, Jens Juul & Madsbad, Sten, Dec 2017, In: Annals of Translational Medicine. 5, 24, 5 p., 505.

    Research output: Contribution to journal › Comment/debate › Research

  11. Published

    The incretin system in healthy humans: The role of GIP and GLP-1

    Holst, Jens Juul, 2019, In: Metabolism. 96, p. 46-55

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Glucagon-like peptide 1 - a new hormone which may change the treatment of non-insulin dependent diabetes mellitus

    Holst, Jens Juul & Ørskov, C., 1992, In: MedView. 6, p. 259-263

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans.

    Holst, Jens Juul & Gromada, J., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 2, p. E199-206

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Effect of intestinal inhibitory peptides on vagally induced secretion from isolated perfused porcine pancreas

    Holst, Jens Juul, Rasmussen, T. N., Harling, H. & Schmidt, P., 1993, In: Pancreas. Vol. 8, no. 1, p. 80-87

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Isolated organs as replacements for vertebrate animals

    Holst, Jens Juul, 1994, Handbook of Laboratory Animal Science. USA: CRC Press, p. 397-408

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  16. Published

    Is there a place for incretin therapies in obesity and prediabetes?

    Holst, Jens Juul & Deacon, Carolyn F., 13 Feb 2013, In: Trends in Endocrinology and Metabolism. 24, 3, p. 145-152 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Neural regulation of pancreatic exocrine funktion

    Holst, Jens Juul, 1993, In: The Pancreas: Biology, Pathobiology an Disease. p. 381-402

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Glucagon and other proglucagon-derived peptides

    Holst, Jens Juul & Ørskov, Cathrine, 1994, Gut Peptides: Biochemistry and Physiology. New York: Raven Press, p. 305-340

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  19. Published

    Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus: focus on bile acid sequestrants

    Holst, Jens Juul & McGill, M. A., 2012, In: Clinical Drug Investigation. 32, 1, p. 1-14 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin

    Holst, Jens Juul, Deacon, Carolyn F., Hartmann, Bolette & Pedersen, Jens, 2013, Handbook of Biologically Active Peptides . Kastin, AJ. (ed.). 2 ed. Elsevier, p. 1241-1250 10 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education

  21. Published

    Erratum to semaglutide seems to be more effective the other GLP-1Ras

    Holst, Jens Juul & Madsbad, Sten, 2018, In: Annals of Translational Medicine. 6, 3, p. 74

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Non-insulin-dependent diabetes mellitus - new drugs?

    Holst, Jens Juul, 1997, In: Drug Discovery Today. 2, p. 128-129

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Somatostatin is an essential paracrine link in acid inhibition of gastrin secretion

    Holst, Jens Juul, Ørskov, Cathrine & Poulsen, S. S., 1992, In: Digestion. 51, p. 95-102

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Incretin based therapies: do they hold their promise?

    Holst, Jens Juul, 2012, In: Journal of Diabetes. 4, 1, p. 4-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Glucagon-like peptide 1 and inhibitors of dipeptidyl peptidase IV in the treatment of type 2 diabetes mellitus.

    Holst, Jens Juul & Deacon, Carolyn F., 2004, In: Current Opinion in Pharmacology. 4, 6, p. 589-96 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Neuromediators in the control of pancreatic secretion

    Holst, Jens Juul, 1993, Neuromediators in the control of pancreatic secretion. Torun: Polish Physiological Society, p. 72-78

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  27. Published

    New Lessons from the gut: Studies of the role of gut peptides in weight loss and diabetes resolution after gastric bypass and sleeve gastrectomy

    Holst, Jens Juul, Madsbad, Sten, Bojsen-Møller, Kirstine Nyvold, Dirksen, C. & Svane, M., 2024, In: Peptides. 176, 9 p., 171199.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    Gut hormones and intestinal function

    Holst, Jens Juul & Schmidt, P., 1994, The Gut as an Endocrine Organ. Clinics in Endocrinology and Metabolism, Vol 8. Bailliere, p. 137-164

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  29. Published

    What combines best with GLP-1 for obesity treatment: GIP receptor agonists or antagonists?

    Holst, Jens Juul, 2021, In: Cell Reports Medicine. 2, 5, 2 p., 100284.

    Research output: Contribution to journal › Comment/debate › Research

  30. Published

    Secretion of neurotensin from isolated perfused porcine ileum

    Holst Pedersen, J., Knuthsen, S., Bernabei, M., Ørskov, Cathrine & Holst, Jens Juul, May 1988, In: Regulatory Peptides. 21, 1-2, p. 13-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Increased Postprandial Response of Glucagon-Like Peptide-2 in Patients with Chronic Pancreatitis and Pancreatic Exocrine Insufficiency

    Hornum, Mads, Pedersen, J. F., Larsen, S., Olsen, O., Holst, Jens Juul & Knop, Filip Krag, 2010, In: Pancreatology. 10, 2-3, p. 201-207 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Dietary impact on fasting and stimulated GLP-1 secretion in different metabolic conditions - a narrative review

    Huber, H., Schieren, A., Holst, Jens Juul & Simon, M., 2024, In: The American Journal of Clinical Nutrition. 119, 3, p. 599-627

    Research output: Contribution to journal › Review › Research › peer-review

  33. Published

    Glucose- and Bile Acid-Stimulated Secretion of Gut Hormones in the Isolated Perfused Intestine Is Not Impaired in Diet-Induced Obese Mice

    Dal, Jenna Elizabeth Hunt, Holst, Jens Juul & Jepsen, Sara Lind, 2022, In: Frontiers in Endocrinology. 13, 10 p., 884501.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Stimulation of the Bile Acid Receptor Tgr5 Promotes Intestinal Growth

    Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Ullmer, C., Holst, Jens Juul & Kissow, Hannelouise, 1 May 2018, In: Gastroenterology. 154, 6 (S1), 1 p., S-333.

    Research output: Contribution to journal › Conference abstract in journal › Research

  35. Published

    GLP-1 and Intestinal Diseases

    Dal, Jenna Elizabeth Hunt, Holst, Jens Juul, Jeppesen, Palle Bekker & Kissow, Hannelouise, 2021, In: Biomedicines. 9, 4, 14 p., 383.

    Research output: Contribution to journal › Review › Research › peer-review

  36. Published

    Intestinal Growth in Glucagon Receptor Knockout Mice is Not Associated with the Formation of Aom/DSS-Induced Tumours

    Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Windeløv, Johanne Agerlin, Galsgaard, Katrine Douglas, Holst, Jens Juul & Kissow, Hannelouise, 1 May 2019, In: Gastroenterology. 156, 6 (S1), 1 p., S-692.

    Research output: Contribution to journal › Conference abstract in journal › Research

  37. Published

    Dietary Fiber is Essential to Maintain L Cell Secretion and Intestinal Weight

    Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 1 May 2019, In: Gastroenterology. 156, 6 (S1), p. S-477

    Research output: Contribution to journal › Conference abstract in journal › Research

  38. Published

    Dietary Fiber Is Essential to Maintain Intestinal Size, L-Cell Secretion, and Intestinal Integrity in Mice

    Dal, Jenna Elizabeth Hunt, Hartmann, Bolette, Schoonjans, K., Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 10 p., 640602.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors

    Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 7 p., 695145.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Pharmacological activation of TGR5 promotes intestinal growth via a GLP-2 dependent pathway in mice

    Dal, Jenna Elizabeth Hunt, Billeschou, Anna, Windeløv, Johanne Agerlin, Hartmann, Bolette, Ullmer, C., Holst, Jens Juul & Kissow, Hannelouise, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 6, p. G980-G987

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Effect of glucagon-like peptide-1 (proglucagon 78-107amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, Jan 1994, In: Metabolism. 43, 1, p. 104-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Effect of glucagon-like peptide-1 (proglucagon 78-107 amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Holst, Jens Juul & Ørskov, C., 1994, In: Metabolism. 43, p. 104-108

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Effect of glucagon-like peptide-1 (proglucagon 78 - 107 amide) on hepatic glucose production in healthy man

    Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, 1994, In: Metabolism. 43, p. 104-108

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Effect of liraglutide treatment on jejunostomy output in patients with short bowel syndrome: An open-label pilot study

    Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R. M., Hartmann, Bolette, Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, Mads, Andersen, Jens Rikardt, Henriksen, B. M., Brøbech Mortensen, P. & Jeppesen, Palle Bekker, 2018, In: Journal of Parenteral and Enteral Nutrition. 42, 1, p. 112-121 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The glucagon-like peptide-1 receptor agonist liraglutide reduces jejunostomy output and improves intestinal absorption in short bowel syndrome patients with intestinal failure: A pilot study

    Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R., Hartmann, B., Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, M., Andersen, Jens Rikardt, Mortensen, P. B. & Jeppesen, P. B., 2015. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  46. Published

    The diurnal variation of bone formation is attenuated in adult patients with type 2 diabetes

    Hygum, K., Starup-Linde, J., Harslor, T., Jørgensen, Niklas Rye, Hartmann, Bolette, Holst, Jens Juul & Langdahl, B. L., 2019, In: European Journal of Endocrinology. 181, 3, p. 221-231

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Glucose ingestion causes cardiac repolarization disturbances in type 1 long QT syndrome patients and healthy subjects

    Hyltén-Cavallius, L., Iepsen, E. W., Christiansen, M., Graff, C., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Hansen, Torben, Torekov, Signe Sørensen & Kanters, Jørgen K., Aug 2017, In: Heart Rhythm. 14, 8, p. 1165-1170 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia

    Hyltén-Cavallius, L., Iepsen, E. W., Albrechtsen, Nicolai Jacob Wewer, Svendstrup, M., Lubberding, Anniek Frederike, Hartmann, Bolette, Jespersen, Thomas, Linneberg, Allan René, Christiansen, M., drb459, drb459, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K., Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Circulation. 135, 18, p. 1705-1719 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Endogenous glucagon-like peptide- 1 and 2 are essential for regeneration after acute intestinal injury in mice

    Hytting-Andreasen, R., Balk-Møller, E., Hartmann, Bolette, Pedersen, Jens, Windeløv, Johanne Agerlin, Holst, Jens Juul & Kissow, Hannelouise, 2018, In: PLoS ONE. 13, 6, p. 1-14 e0198046.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    The glucagon receptor antagonist LY2409021 does not affect gastrointestinal-mediated glucose disposal or the incretin effect in individuals with and without type 2 diabetes

    Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., Forman, Julie Lyng, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 187, 4, p. 507-518 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    The Glucagon Receptor Antagonist LY2409021 has No Effect on Postprandial Glucose in Type 2 Diabetes

    Hædersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Forman, Julie Lyng, van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 186, 2, p. 207-221 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    The role of glucagon in the acute therapeutic effects of SGLT2 inhibition

    Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., van Hall, Gerrit, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes. 69, 12, p. 2619-2629 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Cognitive performance, symptoms and counter-regulation during hypoglycaemia in patients with type 1 diabetes and high or low renin-angiotensin system activity

    Høi-Hansen, T., Pedersen-Bjergaard, U., Andersen, R. D., Kristensen, P. L., Thomsen, C., Kjaer, T., Høgenhaven, H., Smed, A., Holst, J. J., Dela, F., Boomsma, F., Thorsteinsson, B., Høi-Hansen, T., Pedersen-Bjergaard, U., Andersen, R. D., Kristensen, P. L., Thomsen, C., Kjaer, T., Høgenhaven, H., Smed, A. & 4 others, Holst, J. J., Dela, F., Boomsma, F. & Thorsteinsson, B., 2009, In: Journal of the Renin-Angiotensin-Aldosterone System. 10, 4, p. 216-29 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Cognitive performance, symptoms and counter-regulation during hypoglycaemia in patients with type 1 diabetes and high or low renin-angiotensin system activity

    Høi-Hansen, T., Pedersen-Bjergaard, Ulrik, Andersen, R. D., Kristensen, Peter Lommer, Thomsen, C., Kjaer, T., Høgenhaven, H., Smed, A., Holst, Jens Juul, Dela, Flemming, Boomsma, F. & Thorsteinsson, B., Dec 2009, In: Journal of the Renin-Angiotensin-Aldosterone System. 10, 4, p. 216-29 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes

    Højberg, P. V., Zander, M., Vilsbøll, T., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, 1 Apr 2008, In: Diabetologia. 51, 4, p. 632-640 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes

    Højberg, P. V., Vilsbøll, T., Zander, M., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, Nov 2008, In: Diabetic Medicine Online. 25, 11, p. 1268-75 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

    Højberg, P. V., Vilsbøll, Tina, Rabøl, R., Knop, Filip Krag, Bache, M., Krarup, T., Holst, Jens Juul & Madsbad, Sten, 2008, In: Diabetologia. 52, 2, p. 199-207 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Reference intervals for plasma glucose, insulin, proinsulin, C-peptide and counterregulatory factors during a 72-hour fast in healthy human subjects

    Højlund, K., Eshøj, O., Christensen, M. W., Skjærbæk, C., Frystyk, J., Holst, Jens Juul, Koldkjær, O., Møller J., D. & Beck-Nielsen, H., 2001, In: American Journal of Physiology.. 280, p. E50-E58

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    alpha-Glucosidase inhibition (acarbose) fails to enhance secretion of glucagon-like peptide 1 (7-36 amide) and to delay gastric emptying in Type 2 diabetic patients

    Hücking, K., Kostic, Z., Pox, C., Ritzel, R., Holst, Jens Juul, Schmiegel, W. & Nauck, M. A., Apr 2005, In: Diabetic Medicine. 22, 4, p. 470-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Alpha-Glucosidase inhibition (Acarbose) fails to enhance secretion of glucagons-like peptide 1(7-36 amide) and to delay gastric emptying in type 2 diabetic patients

    Hücking, K., Kostic, Z., Pox, C., Ritzel, R., Holst, Jens Juul, Schmiegel, W. & Nauck, M. A., 2005, In: Diabet. Med.. 22, p. 470-476

    Research output: Contribution to journal › Journal article › Research

  61. Published

    Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: an investigator-initiated, randomised, placebo-controlled trial

    Idorn, T., Knop, Filip Krag, Jorgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, M. & Feldt-Rasmussen, B., Sep 2014, In: Diabetologia. 57, 1 supplement, p. S370-S371 909.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  62. Published

    Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: protocol for an investigator-initiated prospective, randomised, placebo-controlled, double-blinded, parallel intervention study

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 26 Apr 2013, In: B M J Open. 3, 4, p. 1-10 11 p., e002764.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Elimination and degradation of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Christensen, Mikkel Bring, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 8 Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 7, p. 2457-66 10 p., jc20133809.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 119-27 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    The authors reply

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Kidney International. 85, 1, p. 212-3 2 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  66. Published

    Gastrointestinal factors contribute to glucometabolic disturbances in nondiabetic patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, May 2013, In: Kidney International. 83, 5, p. 915-23 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Safety and Efficacy of Liraglutide in Patients With Type 2 Diabetes and End-Stage Renal Disease: An Investigator-Initiated, Placebo-Controlled, Double-Blinded, Parallel Group, Randomized Trial

    Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Feb 2016, In: Diabetes Care. 39, 2, p. 206-13 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss

    Iepsen, E. W., Lundgren, J., Dirksen, C., Jensen, J., Pedersen, Oluf Borbye, Hansen, Torben, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2015, In: International journal of obesity (2005). 39, 5, p. 834-41 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Leptin og dens betydning for vægtvedligeholdelse

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2012, In: Klinisk biokemi i Norden. 24, 4, p. 8-15 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    GLP-1 baseret behandling af diabetes og svær overvægt

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2015, In: BestPractice. 9, 4, p. 10-12 3 p.

    Research output: Contribution to journal › Journal article › Communication

  71. Published

    Liraglutide for Type 2 diabetes and obesity: a 2015 update

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2015, In: Expert Review of Cardiovascular Therapy. 13, 7, p. 753-67 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women

    Iepsen, E. P. W., Lundgren, J. R., Hartmann, Bolette, Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, Niklas Rye, Jensen, J. B., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2015, In: The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909 –2917 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Therapies for inter-relating diabetes and obesity - GLP-1 and obesity

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, Dec 2014, In: Expert Opinion on Pharmacotherapy. 15, 17, p. 2487-500 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Successful weight loss maintenance includes long-term increased meal responses of GLP-1 and PYY3-36

    Iepsen, E. W., Lundgren, J., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, Jun 2016, In: European Journal of Endocrinology. 174, 6, p. 775-784 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Patients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor Agonist

    Iepsen, E. W., Zhang, J., Thomsen, Henrik S., Hansen, E. L., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Holm, Jens-Christian & Torekov, Signe Sørensen, 2018, In: Cell Metabolism. 28, 1, p. 23-32.e3

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Adults with pathogenic MC4R mutations have increased final height and thereby increased bone mass

    Iepsen, E. W., Zhang, J., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Jørgensen, Niklas Rye, Holm, Jens-Christian & Torekov, Signe Sørensen, 2020, In: Journal of Bone and Mineral Metabolism. 38, 1, p. 117-125 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    GLP-1 Receptor Agonist Treatment in Morbid Obesity and Type 2 Diabetes Due to Pathogenic Homozygous Melanocortin-4 Receptor Mutation: A Case Report

    Iepsen, E. W., Have, C. T., Veedfald, Simon, Madsbad, Sten, Holst, Jens Juul, Grarup, Niels, Pedersen, Oluf Borbye, Brandslund, I., Holm, Jens-Christian, Hansen, Torben & Torekov, Signe Sørensen, 2020, In: Cell Reports Medicine. 1, 1, 8 p., 100006.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Effects of aerobic training and semaglutide treatment on pancreatic β-cell secretory function in patients with type 2 diabetes

    Ingersen, Arthur, Schmücker, Malte, Alexandersen, C., Graungaard, B., Thorngreen, T., Borch, Jacob, Holst, Jens Juul, Helge, Jørn Wulff & Dela, Flemming, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2798–2811

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Bile acids induce glucagon-like peptide 2 secretion with limited effects on intestinal adaptation in early weaned pigs

    Ipharraguerre, I. R., Tedó, G., Menoyo, D., de Diego Cabero, N., Holst, Jens Juul, Nofrarías, M., Mereu, A. & Burrin, D. G., Dec 2013, In: Journal of Nutrition. 143, 12, p. 1899-905 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Effect of GLP-1 Receptor Agonist Treatment on Body weight in Obese Antipsychotic-treated Patients with Schizophrenia: a Randomized, Placebo-controlled Trial Byline

    Ishøy, P. L., Knop, Filip Krag, Broberg, B. V., Bak, N., Andersen, U. B., Jørgensen, N. R., Holst, Jens Juul, Glenthøj, Birte Yding & Ebdrup, Bjørn, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 162-171

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    High saturated fatty acid intake induces insulin secretion by elevating gastric inhibitory polypeptide levels in healthy individuals

    Itoh, K., Moriguchi, R., Yamada, Y., Fujita, M., Yamato, T., Oumi, M., Holst, Jens Juul & Seino, Y., Aug 2014, In: Nutrition Research. 34, 8, p. 653-60 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Small intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency

    Jackson, R. S., Creemers, J. W. M., Saraf Faraoqi, I., Raffin-Sanson, M. L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicholl, T. M., Lindley, K. J. & 1 others, O Rahlly, S., 2003, In: J. Clin. Invest.. 112, p. 1550-1560

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency

    Jackson, R. S., Creemers, J. W. M., Farooqi, I. S., Raffin-Sanson, M-L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicole, T. M., Milla, P. J. & 2 others, Lindley, K. J. & O'Rahilly, S., Nov 2003, In: The Journal of Clinical Investigation. 112, 10, p. 1550-60 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Changes in Gastrointestinal Hormone Responses, Insulin Sensitivity, and Beta-Cell Function Within 2 Weeks After Gastric Bypass in Non-diabetic Subjects

    Jacobsen, S. H., Olesen, S. C., Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Worm, Dorte, Almdal, Thomas Peter, Naver, L. S., Hvolris, L. E., Rehfeld, Jens Frederik, Wulff, B. S., Clausen, T. R., Hansen, D. L., Holst, Jens Juul & Madsbad, Sten, 2012, In: Obesity Surgery. 22, 7, p. 1084-96 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Remission af type 2-diabetes efter gastric bypass-kirurgi: et medicinsk mysterium?

    Jacobsen, S., Hansen, D. L., Worm, Dorte, Madsbad, Sten, Hvolris, L. E., Naver, L. P. S. & Holst, Jens Juul, 2009, In: Behandlerbladet. p. 20-29 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Effects of gastric bypass surgery on glucose absorption and metabolism during a mixed meal in glucose-tolerant individuals

    Jacobsen, S. H., Bojsen-Møller, K. N., Dirksen, C., Jørgensen, N. B., Clausen, T. R., Wulff, B. S., Kristiansen, V. B., Worm, Dorte, Hansen, D. L., Holst, Jens Juul, van Hall, Gerrit & Madsbad, Sten, Oct 2013, In: Diabetologia. 56, 10, p. 2250-4 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs

    Jain, A. K., Stoll, B., Burrin, D. G., Holst, Jens Juul & Moore, D. D., 2012, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 302, 2, p. G218-24

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Glucagon Receptor Signaling and Glucagon Resistance

    Janah, L., Kjeldsen, Sasha Alexandra Sampson, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Stojanovska, E., Pedersen, Jens, Knop, Filip Krag, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2019, In: International Journal of Molecular Sciences. 20, 13, 27 p., 3314.

    Research output: Contribution to journal › Review › Research › peer-review

  89. Published

    GLP-1 defects in diabetes

    Janus, C., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2 Feb 2015

    Research output: Other contribution › Net publication - Internet publication › Research › peer-review

  90. Published

    Habitual activity associates with lower fasting and greater glucose-induced GLP-1 response in men

    Janus, C., Vistisen, D., Amadid, H., Witte, D. R., Lauritzen, T., Brage, S., Bjerregaard, A., Hansen, Torben, Holst, Jens Juul, Jørgensen, M. E., Pedersen, Oluf Borbye, Færch, K. & Torekov, Signe Sørensen, 2019, In: Endocrine Connections. 8, 12, p. 1607–1617 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Gastric Bypass with Different Biliopancreatic Limb Lengths Results in Similar Post-absorptive Metabolomics Profiles

    Jarak, I., Pereira, S. S., Carvalho, R. A., Oliveira, P. F., Alves, M. G., Guimarães, M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2020, In: Obesity Surgery. 30, 3, p. 1068-1078 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    The imprinted gene Delta like non-canonical notch ligand 1 (Dlk1) associates with obesity and triggers insulin resistance through inhibition of skeletal muscle glucose uptake

    Jensen, C. H., Kosmina, R., Rydén, M., Baun, C., Hvidsten, S., Andersen, M. S., Christensen, L. L., Gastaldelli, A., Marraccini, P., Arner, P., Jørgensen, C. D., Laborda, J., Holst, Jens Juul & Andersen, D. C., 2019, In: EBioMedicine. 46, p. 368-380 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Responses of gut and pancreatic hormones, bile acids, and fibroblast growth factor-21 differ to glucose, protein, and fat ingestion after gastric bypass surgery

    Jensen, C. Z., Bojsen-Møller, K. N., Svane, M. S., Holst, L. M., Hermansen, K., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Kristiansen, V. B., Rehfeld, Jens Frederik, Clausen, T. R., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 4, p. G661-G672 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men

    Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, Flemming, Madsbad, Sten & Vaag, Allan, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2775-83 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Young, low-birth-weight men are not more susceptible to the diabetogenic effects of a prolonged free fatty acid exposure than matched controls.

    Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, Flemming, Madsbad, Sten & Vaag, Allan, 2005, In: Metabolism - Clinical and Experimental. 54, 10, p. 1398-406 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men

    Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, F., Madsbad, Sten & Vaag, A. A., 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 6, p. 2775-2783 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight.

    Jensen, C. B., Storgaard, H., Dela, Flemming, Holst, Jens Juul, Madsbad, Sten & Vaag, Allan, 2002, In: Diabetes. 51, 4, p. 1271-80 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes

    Jensen, D. H., Aaboe, K., Henriksen, J. E., Vølund, A., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2012, In: Diabetologia. 55, 5, p. 1406-16 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    GLP-1-induced renal vasodilation in rodents depends exclusively on the known GLP-1 receptor and is lost in pre-hypertensive rats

    Jensen, E. P., Møller, S., Hviid, A. V. R., Veedfald, Simon, Holst, Jens Juul, Pedersen, Jens, Ørskov, Cathrine & Sorensen, Charlotte Mehlin, 2020, In: American Journal of Physiology: Renal Physiology. 318, 6, p. F1409-F1417

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow

    Jensen, E. P., Poulsen, Steen Seier, Kissow, Hannelouise, von Holstein-Rathlou, Niels-Henrik, Deacon, Carolyn F., Jensen, B. L., Holst, Jens Juul & Sorensen, Charlotte Mehlin, 15 Apr 2015, In: A J P: Renal Physiology (Online). 308, 8, p. F867-F877 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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