Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 2015
- Published
GLP1 and glucagon co-secreting pancreatic neuroendocrine tumor presenting as hypoglycemia after gastric bypass
Guimarães, M., Rodrigues, P., Pereira, S. S., Nora, M., Gonçalves, G., Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Holst, Jens Juul & Monteiro, M. P., 2015, In: Endocrinology, Diabetes & Metabolism Case Reports. 2015, p. 1-5 5 p., 150049.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired incretin effect is an early sign of glucose dysmetabolism in nondiabetic patients with psoriasis
Gyldenløve, M., Vilsbøll, Tina, Zachariae, Claus, Holst, Jens Juul, Knop, Filip Krag & Skov, Lone, 11 Nov 2015, In: Journal of Internal Medicine. 278, 6, p. 660-70 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with psoriasis are insulin resistant
Gyldenløve, M., Storgaard, H., Holst, Jens Juul, Vilsbøll, T., Knop, Filip Krag & Skov, Lone, Apr 2015, In: Journal of the American Academy of Dermatology. 72, 4, p. 599-605 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Central 5-HT Neurotransmission Modulates Weight Loss following Gastric Bypass Surgery in Obese Individuals
Haahr, M. E., Hansen, D. L., Fisher, P. M., Svarer, C., Stenbæk, D. S., Madsen, K., Madsen, J., Holst, Jens Juul, Baaré, W. F. C., Højgaard, Liselotte, Almdal, T. & Knudsen, G. M., 8 Apr 2015, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 35, 14, p. 5884-5889 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined N-terminal and C-terminal truncations of Glucose dependent Insulinotropic Polypeptide (GIP) are potent and efficient GIP receptor antagonists
Hansen, L. S., wbf943, wbf943, Svendsen, B., Christensen, M., Hartmann, Bolette, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Sep 2015, In: Diabetologia. 58, 1 supplement, p. S276-S277 2 p., 569.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Important species differences regarding lymph contribution to gut hormone responses
Hansen, M., Hjøllund, K. R., Hartmann, Bolette, Plamboeck, A., Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 28-31 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric bypass surgery has a weight-loss independent effect on post-challenge serum glucose levels
Hofsø, D., Birkeland, K. I., Holst, Jens Juul, Bollerslev, J., Sandbu, R., Røislien, J. & Hjelmesæth, J., 2015, In: Diabetology & Metabolic Syndrome. 7, p. 1-4 4 p., 69.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagon-like peptide-1 receptor agonist liraglutide reduces jejunostomy output and improves intestinal absorption in short bowel syndrome patients with intestinal failure: A pilot study
Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R., Hartmann, B., Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, M., Andersen, Jens Rikardt, Mortensen, P. B. & Jeppesen, P. B., 2015. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Treatment with a GLP-1 receptor agonist diminishes the decrease in free plasma leptin during maintenance of weight loss
Iepsen, E. W., Lundgren, J., Dirksen, C., Jensen, J., Pedersen, Oluf Borbye, Hansen, Torben, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2015, In: International journal of obesity (2005). 39, 5, p. 834-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 baseret behandling af diabetes og svær overvægt
Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2015, In: BestPractice. 9, 4, p. 10-12 3 p.Research output: Contribution to journal › Journal article › Communication
- Published
GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women
Iepsen, E. P. W., Lundgren, J. R., Hartmann, Bolette, Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, Niklas Rye, Jensen, J. B., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2015, In: The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909 –2917 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide for Type 2 diabetes and obesity: a 2015 update
Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2015, In: Expert Review of Cardiovascular Therapy. 13, 7, p. 753-67 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 defects in diabetes
Janus, C., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2 Feb 2015Research output: Other contribution › Net publication - Internet publication › Research › peer-review
- Published
Activation of GLP-1 receptors on vascular smooth muscle cells reduces the autoregulatory response in afferent arterioles and increases renal blood flow
Jensen, E. P., Poulsen, Steen Seier, Kissow, Hannelouise, von Holstein-Rathlou, Niels-Henrik, Deacon, Carolyn F., Jensen, B. L., Holst, Jens Juul & Sorensen, Charlotte Mehlin, 15 Apr 2015, In: A J P: Renal Physiology (Online). 308, 8, p. F867-F877 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of gastrointestinal factors on glucose metabolism in patients with cirrhosis
Junker, A. E., Gluud, Lise Lotte, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Oct 2015, In: Journal of Gastroenterology and Hepatology. 30, 10, p. 1522-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clearance of glucoregulatory peptide hormones during haemodialysis and haemodiafiltration in non-diabetic end-stage renal disease patients
Jørgensen, M. B., Idorn, T., Knop, Filip Krag, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Mar 2015, In: Nephrology, Dialysis, Transplantation. 30, 3, p. 513-20 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improvements in glucose metabolism early after gastric bypass surgery are not explained by increases in total bile acids and fibroblast growth factor 19 concentrations
Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Kristiansen, V. B., Wulff, B. S., Rainteau, D., Humbert, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Clausen, T. R., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. E396-406 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying and disease activity in inflammatory bowel disease
Keller, J., Binnewies, U., Rösch, M., Holst, Jens Juul, Beglinger, C., Andresen, V. & Layer, P., 2015, In: European Journal of Clinical Investigation. 45, 12, p. 1234-42 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin and glucagon levels in adult offspring exposed to maternal diabetes in pregnancy
Kelstrup, L., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Hansen, Torben, Holst, Jens Juul & Damm, Peter, 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1967-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol
Kleberg, K., Jacobsen, A. K., Ferreira, J. G., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik, Holst, Jens Juul, de Araujo, I. E. & Hansen, Harald S., 16 Jan 2015, In: The Journal of Physiology. 593, 8, p. 2097-109 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of acute exercise on pancreatic endocrine function in subjects with type 2 diabetes
Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul, Pedersen, Bente Klarlund & Solomon, T., Feb 2015, In: Diabetes, Obesity and Metabolism. 17, 2, p. 207-210 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Molecular Mechanisms of Glucose-Stimulated GLP-1 Secretion From Perfused Rat Small Intestine
Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Feb 2015, In: Diabetes. 64, 2, p. 370-382 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose stimulates neurotensin secretion from the rat small intestine by mechanisms involving SGLT1 and GLUT2 leading to cell depolarization and calcium influx
Kuhre, Rune Ehrenreich, Bechmann, L. E., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 21 Apr 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 12, p. E1123–E1130 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurement of the incretin hormones: glucagon-like peptide-1 and glucose-dependent insulinotropic peptide
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, Apr 2015, In: Journal of Diabetes and its Complications. 29, 3, p. 445-450 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of TNF-α on GLP-1-stimulated plasma glucose kinetics
Lehrskov-Schmidt, L., Lehrskov-Schmidt, L., Nielsen, S. T., Holst, Jens Juul, Møller, K. & Solomon, T. P. J., Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E616-E622 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin effect after oral amino Acid ingestion in humans
Lindgren, O., Pacini, G., Tura, A., Holst, Jens Juul, Deacon, Carolyn F. & Ahrén, B., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. 1172-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preoperative β-cell function in patients with type 2 diabetes is important for the outcome of Roux-en-Y gastric bypass surgery
Lund, M. T., Hansen, M., Skaaby, Stinna, Dalby, S., Støckel, M., Floyd, A. K., Bech, K., Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, 13 Apr 2015, In: The Journal of Physiology. 593, 14, p. 3123-33 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans.
Mandøe, M. J., Hansen, K. B., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul & Hansen, Harald S., 2015, In: The American Journal of Clinical Nutrition. 102, 3, p. 548-555 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of moderate- and high-intensity acute exercise on appetite in obese individuals
Martins, C., Stensvold, D., Finlayson, G., Holst, Jens Juul, Wisloff, U., Kulseng, B., Morgan, L. & King, N. A., Jan 2015, In: Medicine and Science in Sports and Exercise. 47, 1, p. 40-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immediate enhancement of first-phase insulin secretion and unchanged glucose effectiveness in patients with type 2 diabetes after Roux-en-Y gastric bypass
Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Jacobsen, S. H., Jørgensen, N. B., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 15 Mar 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 6, p. E535-44 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism
Mikkelsen, K. H., Frost, M., Bahl, M. I., Licht, T. R., Jensen, U. S., Rosenberg, Jacob, Pedersen, Oluf Borbye, Hansen, Torben, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 12 Nov 2015, In: PLOS ONE. 10, 11, p. 1-14 e0142352.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine
Pedersen, Jens, B. Pedersen, N., Brix, S. W., Grunddal, Kaare Villum, Rosenkilde, Mette, Hartmann, Bolette, Ørskov, Cathrine, Poulsen, Steen Seier & Holst, Jens Juul, May 2015, In: Peptides. 67, p. 20-28 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 309, 5, p. R544-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual-hormone treatment with insulin and glucagon in patients with type 1 diabetes
Reiband, H. K., Schmidt, S., Ranjan, A., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, 2015, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 31, 7, p. 672-9 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effect of Roux-en-Y gastric bypass on the distribution and hormone expression of small-intestinal enteroendocrine cells in obese patients with type 2 diabetes
Rhee, N. A., Wahlgren, C. D., Pedersen, J., Mortensen, B., Langholz, E., Wandall, E. P., Friis, S. U., Vilmann, Peter, Paulsen, S. J., Kristiansen, V. B., Jelsing, J., Dalbøge, L. S., Poulsen, Steen Seier, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetologia. 58, 10, p. 2254-2258 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Inability to match energy intake with energy expenditure at sustained near-maximal rates of energy expenditure in older men during a 14-d cycling expedition
Rosenkilde Larsen, M., Morville, T., Riis Andersen, P., Kjær, K., Rasmusen, H., Holst, Jens Juul, Dela, Flemming, Westerterp, K., Sjödin, Anders Mikael & Helge, Jørn Wulff, 2015, In: American Journal of Clinical Nutrition. 102, 6, p. 1398-1405 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specific inhibition of bile acid transport alters plasma lipids and GLP-1
Rudling, M., Camilleri, M., Graffner, H., Holst, Jens Juul & Rikner, L., 2015, In: B M C Cardiovascular Disorders. 15, p. 1-8 8 p., 75.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like Peptide-1 in type 2 diabetes patients
Samocha-Bonet, D., Chisholm, D. J., Holst, Jens Juul & Greenfield, J. R., 2015, In: Nutrients. 7, 4, p. 2101-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of sitagliptin on counterregulatory and incretin hormones during acute hypoglycaemia in patients with type 1 diabetes: a randomized double blind placebo-controlled cross-over study
Schopman, J. E., Hoekstra, J. B. L., Frier, B. M., Ackermans, M. T., de Sonnaville, J. J. J., Stades, A. M., Zwertbroek, R., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Holleman, F., Jun 2015, In: Diabetes, Obesity and Metabolism. 17, 6, p. 546-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypoglycemia-associated changes in the electroencephalogram in patients with type 1 diabetes and normal hypoglycemia awareness or unawareness
Sejling, A., Kjær, T. W., Pedersen-Bjergaard, Ulrik, Diemar, S. S., Frandsen, C. S. S., Hilsted, L., Faber, Jens, Holst, Jens Juul, Tarnow, L., Nielsen, M. N., Remvig, L. S., Thorsteinsson, B. & Juhl, C. B., May 2015, In: Diabetes. 64, 5, p. 1760-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes
Sejling, A., Lange, Kai, Frandsen, C. S., Diemar, S. S., Tarnow, L., Faber, Jens, Holst, Jens Juul, Hartmann, Bolette, Hilsted, Linda, Kjaer, T. W., Juhl, C. B., Thorsteinsson, B. & Pedersen-Bjergaard, Ulrik, 2015, In: Diabetologia. 58, p. 1898–1906 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs
Shen, René Liang, Thymann, Thomas, Østergaard, M. V., Støy, A. C. F., Krych, Lukasz, Nielsen, Dennis Sandris, Lauridsen, C., Hartmann, Bolette, Holst, Jens Juul, Burrin, D. G. & Sangild, Per Torp, 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 309, 5, p. G310-G323 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intake of Lactobacillus reuteri Improves Incretin and Insulin Secretion in Glucose-Tolerant Humans: A Proof of Concept
Simon, M., Strassburger, K., Nowotny, B., Kolb, H., Nowotny, P., Burkart, V., Zivehe, F., Hwang, J., Stehle, P., Pacini, G., Hartmann, Bolette, Holst, Jens Juul, MacKenzie, C., Bindels, L. B., Martinez, I., Walter, J., Henrich, B., Schloot, N. C. & Roden, M., 2015, In: Diabetes Care. 38, 10, p. 1827-34 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of glucagon-like peptide-1 on microvascular recruitment and glucose metabolism in short- and long-term Insulin resistance
Sjøberg, K. A., Rattigan, S., Jeppesen, J. F., Lundsgaard, Anne-Marie, Holst, Jens Juul & Kiens, Bente, 2015, In: Journal of Physiology. 593, 9, p. 2185-2198 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of insulin therapy on weight gain and fat distribution in the HF/HS-STZ rat model of type 2 diabetes
Skovsø, S., Damgaard, J., Fels, J. J., Olsen, G. S., Wolf, X. A., Rolin, B. & Holst, Jens Juul, 2015, In: International Journal of Obesity. 39, 10, p. 1531-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Updates in weight loss surgery and gastrointestinal peptides
Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten & Holst, Jens Juul, Feb 2015, In: Current Opinion in Endocrinology, Diabetes and Obesity. 22, 1, p. 21-8 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
An Analysis of Cosecretion and Coexpression of Gut Hormones From Male Rat Proximal and Distal Small Intestine
Svendsen, B., Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Toräng, S., Rehfeld, Jens Frederik, Poulsen, Steen Seier & Holst, Jens Juul, Mar 2015, In: Endocrinology. 156, 3, p. 847-857 11 p., en20141710.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endogenous GLP-1 mediates postprandial reductions in activation in central reward and satiety areas in patients with type 2 diabetes
Ten Kulve, J. S., Veltman, D. J., van Bloemendaal, L., Barkhof, F., Deacon, Carolyn F., Holst, Jens Juul, Konrad, R. J., Sloan, J. H., Drent, M. L., Diamant, M. & IJzerman, R. G., Dec 2015, In: Diabetologia. 58, 12, p. 2688-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The anorexic hormone Peptide YY3-36 is rapidly metabolized to inactive Peptide YY3-34 in vivo.
Toräng, S., Veedfald, Simon, Rosenkilde, Mette, Hartmann, Bolette & Holst, Jens Juul, 20 Jul 2015, In: Physiological Reports. 3, 7, p. 1-8 8 p., e12455.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic polypeptide responses to isoglycemic oral and intravenous glucose in humans with and without intact vagal innervation
Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Svendsen, Lars Bo, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 229-31 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients
Yabe, D., Kuroe, A., Watanabe, K., Iwasaki, M., Hamasaki, A., Hamamoto, Y., Harada, N., Yamane, S., Lee, S., Murotani, K., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N., Kurose, T. & Seino, Y., 2015, In: Journal of Diabetes and its Complications. 29, p. 413-421 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bile acid mediated effects on gut integrity and performance of early-weaned piglets
de Diego-Cabero, N., Mereu, A., Menoyo, D., Holst, Jens Juul & Ipharraguerre, I. R., 2015, In: B M C Veterinary Research. 11, 1, p. 1-8 8 p., 111.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young
Østoft, S. H., Bagger, J. I., Hansen, Torben, Hartmann, Bolette, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 1 Aug 2015, In: European Journal of Endocrinology. 173, 2, p. 205-215 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?
Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting the intestinal L-cell for obesity and type 2 diabetes treatment
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Deacon, Carolyn F. & Holst, Jens Juul, 1 Jan 2014, In: Expert Review of Endocrinology & Metabolism. 9, 1, p. 61-72 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Defining the role of GLP-1 in the enteroinsulinar axis in type 2 diabetes using DPP-4 inhibition and GLP-1 receptor blockade
Aulinger, B. A., Bedorf, A., Kutscherauer, G., de Heer, J., Holst, Jens Juul, Göke, B. & Schirra, J., Mar 2014, In: Diabetes. 63, 3, p. 1079-92 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous glucose infusions in patients with type 2 diabetes and healthy individuals
Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, Holst, Jens Juul & Vilsbøll, T., 31 May 2014, In: Diabetologia. 57, 8, p. 1270-25 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specificity and sensitivity of commercially available assays for glucagon and oxyntomodulin measurement in humans
Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hartmann, Bolette, Christensen, M., Vilsbøll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: European Journal of Endocrinology. 170, 4, p. 529-538 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): Implications for GLP-1 measurements in clinical studies
Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Knop, Filip Krag, Vilsbøll, Tina, Jørgensen, N. B., Hartmann, Bolette, Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Diabetes, Obesity and Metabolism. 16, 11, p. 1155-1164 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No Effect of Aprotinin (Trasylol) on Degradation of Exogenous and Endogenous Glucagon in Human, Mouse and Rat Plasma
Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Pedersen, Jens, Christensen, M., Vilsboll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Journal of Endocrinology and Diabetes. 1, 1, p. 1-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin secretion: direct mechanisms
Balk-Møller, E., Holst, Jens Juul & Kuhre, Rune Ehrenreich, 12 Jun 2014, Diapedia: The living textbook of diabetes. European Association for the Study of Diabetes (EASD), p. 1-3 3 p.Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Communication
- Published
Effects of hydrolysed casein, intact casein and intact whey protein on energy expenditure and appetite regulation: a randomised, controlled, cross-over study
Bendtsen, L. Q., Lorenzen, J. K., Gomes, S., Liaset, B., Holst, Jens Juul, Ritz, C., Reitelseder, S., Sjödin, Anders Mikael & Astrup, A., 2014, In: British Journal of Nutrition. 112, 8, p. 1412-1422 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely
Bjerg, A. T., Kristensen, M. B., Ritz, C., Holst, Jens Juul, Rasmussen, C., Leser, T. D., Wellejus, A. & Astrup, A., 2014, In: Appetite. 82, p. 111-118 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early enhancements of hepatic and later of peripheral insulin sensitivity combined with increased postprandial insulin secretion contribute to improved glycemic control after Roux-en-Y gastric bypass
Bojsen-Møller, K. N., Dirksen, C., Jørgensen, N. B., Jacobsen, S. H., Serup, A. K. L., Albers, P. H., Hansen, D. L., Worm, D., Naver, L., Kristiansen, V. B., Wojtaszewski, Jørgen F P, Kiens, Bente, Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2014, In: Diabetes. 63, 5, p. 1725-1737 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent Insulinotropic Polypeptide: Blood Glucose Stabilizing Effects in Patients With Type 2 Diabetes
Christensen, Mikkel Bring, Calanna, S., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Mar 2014, In: The Journal of clinical endocrinology and metabolism. 99, 3, p. E418-26 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucometabolic hormones and cardiovascular risk markers in antipsychotic-treated patients
Ebdrup, Bjørn, Knop, Filip Krag, Madsen, A., Mortensen, H. B., Søgaard, B., Holst, Jens Juul, Szecsi, P. B. & Lublin, H., Sep 2014, In: Journal of Clinical Psychiatry. 75, 9, p. e899-905 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of GLP-1 on myocardial glucose metabolism in healthy men during normo- or hypoglycemia
Gejl, M., Lerche, S., Mengel, A., Møller, N., Bibby, B. M., Smidt, K., Brock, Birgitte, Søndergaard, H., Bøtker, H. E., Gjedde, Albert, Holst, Jens Juul, Hansen, S. B. & Rungby, J., 2014, In: PLOS ONE. 9, 1, p. 1-10 10 p., e83758.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of IL-6 on the insulin sensitivity in patients with type 2 diabetes
Harder-Lauridsen, N. M., Krogh-Madsen, Rikke, Holst, Jens Juul, Plomgaard, P., Leick, L., Pedersen, Bente Klarlund & Fischer, C. P., 1 Apr 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 7, p. E769-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distal gastrectomy in pancreaticoduodenectomy is associated with accelerated gastric emptying, enhanced postprandial release of GLP-1, and improved insulin sensitivity
Harmuth, S., Wewalka, M., Holst, Jens Juul, Nemecek, R., Thalhammer, S., Schmid, R., Sahora, K., Gnant, M. & Miholić, J., Jan 2014, In: Journal of Gastrointestinal Surgery. 18, 1, p. 52-9 8 p.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Effects of concentrated arabinoxylan and β-glucan compared with refined wheat and whole grain rye on glucose and appetite in subjects with the metabolic syndrome: a randomized study
Hartvigsen, M. L., Gregersen, S., Lærke, H. N., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., Jan 2014, In: European Journal of Clinical Nutrition. 68, 1, p. 84-90 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial effects of test meals including concentrated arabinoxylan and whole grain rye in subjects with the metabolic syndrome: a randomised study
Hartvigsen, M. L., Lærke, H. N., Overgaard, A., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., May 2014, In: European Journal of Clinical Nutrition. 68, 5, p. 567-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease: an investigator-initiated, randomised, placebo-controlled trial
Idorn, T., Knop, Filip Krag, Jorgensen, M. B., Jensen, T., Resuli, M., Hansen, P. M., Christensen, Karl Bang, Holst, Jens Juul, Hornum, M. & Feldt-Rasmussen, B., Sep 2014, In: Diabetologia. 57, 1 supplement, p. S370-S371 909.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Elimination and degradation of glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with end-stage renal disease
Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Christensen, Mikkel Bring, Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, 8 Apr 2014, In: The Journal of clinical endocrinology and metabolism. 99, 7, p. 2457-66 10 p., jc20133809.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease
Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 119-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The authors reply
Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Kidney International. 85, 1, p. 212-3 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Therapies for inter-relating diabetes and obesity - GLP-1 and obesity
Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, Dec 2014, In: Expert Opinion on Pharmacotherapy. 15, 17, p. 2487-500 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High saturated fatty acid intake induces insulin secretion by elevating gastric inhibitory polypeptide levels in healthy individuals
Itoh, K., Moriguchi, R., Yamada, Y., Fujita, M., Yamato, T., Oumi, M., Holst, Jens Juul & Seino, Y., Aug 2014, In: Nutrition Research. 34, 8, p. 653-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar weight-adjusted insulin secretion and insulin sensitivity in short-duration late autoimmune diabetes of adulthood (LADA) and Type 2 diabetes: Action LADA 8
Juhl, C. B., Bradley, U., Holst, Jens Juul, Leslie, R. D., Yderstraede, K. B., Hunter, S. & Action LADA Consortium, A. L. C., 15 Mar 2014, In: Diabetic Medicine. 31, 8, p. 941-945Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A 25-year-old woman with type 2 diabetes and liver disease
Junker, A. E., Gluud, Lise Lotte, Pedersen, J., Langhoff, J. L., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2014, In: Case Reports in Gastroenterology. 8, 3, p. 398-403 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms behind the superior effects of interval vs continuous training on glycaemic control in individuals with type 2 diabetes: a randomised controlled trial
Karstoft, K., Winding, K., Knudsen, S. H., James, N. G., Scheel, M. M., Olesen, J., Holst, Jens Juul, Pedersen, Bente Klarlund & Solomon, T., 2014, In: Diabetologia. 57, 10, p. 2081-2093 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unprecedented high insulin secretion in a healthy human subject after intravenous glucagon-like peptide-1: a case report
Knop, Filip Krag, Lund, Asger Bach, Madsbad, Sten, Holst, Jens Juul, Krarup, T. & Vilsbøll, T., 2014, In: BMC Research Notes. 7, p. 1-6 6 p., 326.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fructose stimulates GLP-1 but not GIP secretion in mice, rats, and humans
Kuhre, Rune Ehrenreich, Gribble, F. M., Hartmann, Bolette, Reimann, F., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik & Holst, Jens Juul, 1 Apr 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 306, 7, p. G622-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 Amidation Efficiency Along the Length of the Intestine in Mice, Rats and Pigs and in GLP-1 Secreting Cell Lines
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Windeløv, Johanne Agerlin, Svendsen, B., Hartmann, Bolette & Holst, Jens Juul, 31 Jan 2014, In: Peptides. 55, p. 52-57 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose Stimulates GLP-1 Secretion from Isolated Perfused Rat Small Intestine by SGLT1 and GLUT2 Mediated Uptake, Causing V-gated Calcium Channel Activation
Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Jun 2014, In: Diabetes. 63, suppl 1, p. A491 1 p., Abstract no 1915-P.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Pancreatic effects of GLP-1
Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 22 Dec 2014, Diapedia: The Living Textbook of Diabetes. European Association for the Study of Diabetes (EASD)Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Communication
- Published
Does a GLP-1 receptor agonist change glucose tolerance in patients treated with antipsychotic medications? Design of a randomised, double-blinded, placebo-controlled clinical trial
Larsen, J. R., Vedtofte, L., Holst, Jens Juul, Oturai, P., Kjær, Andreas, Corell, C. U., Vilsbøll, T. & Fink-Jensen, Anders, 2014, In: B M J Open. 4, 3, p. 1-9 9 p., e004227.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin effect does not differ in trained and untrained, young, healthy men
Lund, M. T., Dalby, S., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, Mar 2014, In: Acta Physiologica. 210, 3, p. 565-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 as a Mediator in the Remission of Type 2 Diabetes After Gastric Bypass and Sleeve Gastrectomy Surgery
Madsbad, Sten & Holst, Jens Juul, Oct 2014, In: Diabetes. 63, 10, p. 3172-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of changes in glucose metabolism and bodyweight after bariatric surgery
Madsbad, Sten, Dirksen, C. & Holst, Jens Juul, Feb 2014, In: The Lancet Diabetes & Endocrinology. 2, 2, p. 152-64 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Consumption of a diet low in advanced glycation end products for 4 weeks improves insulin sensitivity in overweight women
Mark, A. B., Poulsen, M. W., Andersen, S., Andersen, J. M., Bak, M. J., Ritz, C., Holst, Jens Juul, Nielsen, J., de Courten, B., Dragsted, Lars Ove & Bügel, Susanne Gjedsted, 2014, In: Diabetes Care. 37, 1, p. 88-95 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance
Matikainen, N., Bogl, L. H., Hakkarainen, A., Lundbom, J., Lundbom, N., Kaprio, J., Rissanen, A., Holst, Jens Juul & Pietiläinen, K. H., Jan 2014, In: Diabetes Care. 37, 1, p. 242-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance alters islet morphology in nondiabetic humans
Mezza, T., Muscogiuri, G., Sorice, G. P., Clemente, G., Hu, J., Pontecorvi, A., Holst, Jens Juul, Giaccari, A. & Kulkarni, R. N., Mar 2014, In: Diabetes. 63, 3, p. 994-1007 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans
Nissen, A., Christensen, Mikkel Bring, Knop, Filip Krag, Vilsbøll, T., Holst, Jens Juul & Hartmann, Bolette, Nov 2014, In: The Journal of clinical endocrinology and metabolism. 99, 11, p. E2325-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial
Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3
Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo
Panaro, B. L., Tough, I. R., Engelstoft, M. S., Matthews, R. T., Digby, G. J., Møller, C. L., Svendsen, B., Gribble, F., Reimann, F., Holst, Jens Juul, Holst, Birgitte, Schwartz, Thue W., Cox, H. M. & Cone, R. D., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 1018-29 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute effects of monounsaturated fat on postprandial lipemia and gene expression in first-degree relatives of subjects with type 2 diabetes
Pietraszek, A., Gregersen, S., Pedersen, S. B., Holst, Jens Juul & Hermansen, K., 14 May 2014, In: European Journal of Clinical Nutrition. 68, p. 1022-28 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of dietary advanced glycation end products on postprandial appetite, inflammation, and endothelial activation in healthy overweight individuals
Poulsen, M. W., Bak, M. J., Andersen, J. M., Monošík, R., Giraudi-Futin, A. C., Holst, Jens Juul, Nielsen, J., Lauritzen, Lotte, Larsen, L. H., Bügel, Susanne Gjedsted & Dragsted, Lars Ove, 2014, In: European Journal of Nutrition. 53, 2, p. 661-672 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects
Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The use of double-balloon enteroscopy in retrieving mucosal biopsies from the entire human gastrointestinal tract
Rhee, N. A., Vilmann, Peter, Hassan, H., Hendel, J. W., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Sep 2014, In: Scandinavian Journal of Gastroenterology. 49, 9, p. 1143-1149 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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