Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 1977
- Published
Effects of glucagon-like peptide-1 (GLP-1) on glucose elimination in healthy subjects depends on the pancreatic glucoregulatory hormones.
Shalev, A., Holst, Jens Juul & Keller, M., 1977, In: European Journal of Clinical Investigation. 27, p. 10-16Research output: Contribution to journal › Journal article › Research › peer-review
- 1986
- Published
Glucagon-like peptides GLP-1 and GLP-2, predicted products of the glucagon gene, are secreted separately from pig small intestine but not pancreas
Holst, Jens Juul & Poulsen, Steen Seier, Oct 1986, In: Endocrinology. 119, 4, p. 1467-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1987
- Published
Immunohistochemical detection of ganglia in the rat stomach serosa, containing neurons immunoreactive for gastrin-releasing peptide and vasoactive intestinal peptide
Poulsen, Steen Seier & Holst, Jens Juul, 1987, In: Histochemistry. 87, 1, p. 47-52 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut
Holst, Jens Juul, Ørskov, Cathrine, Nielsen, Olaf & Schwartz, Thue W., 1987, In: F E B S Letters. 211, 2, p. 169-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radio-immunoassays for glucagon-like peptides 1 and 2 (GLP-1 and GLP-2)
Ørskov, Cathrine & Holst, Jens Juul, Apr 1987, In: Scandinavian Journal of Clinical and Laboratory Investigation. Supplement. 47, 2, p. 165-74 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastrin-releasing peptide in the porcine pancreas
Holst, Jens Juul & Poulsen, Steen Seier, May 1987, In: Gastroenterology. 92, 5 Pt 1, p. 1153-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GRP nerves in pig antrum: role of GRP in vagal control of gastrin secretion
Holst, Jens Juul & Poulsen, Steen Seier, Nov 1987, In: American Journal of Physiology (Consolidated). 253, 5 Pt 1, p. G643-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Localization in the gastrointestinal tract of immunoreactive prosomatostatin
Holst, Jens Juul & Poulsen, Steen Seier, Nov 1987, In: Regulatory Peptides. 19, 3-4, p. 183-95 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic and intestinal processing of proglucagon in man
Holst, Jens Juul & Poulsen, Steen Seier, Nov 1987, In: Diabetologia. 30, 11, p. 874-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GRP-producing nerves control antral somatostatin and gastrin secretion in pigs
Holst, Jens Juul, Ørskov, Cathrine & Poulsen, Steen Seier, Dec 1987, In: American Journal of Physiology (Consolidated). 253, 6 Pt 1, p. G767-74Research output: Contribution to journal › Journal article › Research › peer-review
- 1988
- Published
The gastric acid secretagogue gastrin-releasing peptide and the inhibitor oxyntomodulin do not exert their effect directly on the parietal cell in the rat
Poulsen, Steen Seier & Holst, Jens Juul, 1988, In: Digestion. 40, 3, p. 144-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of Gastrin‐Releasing Peptide in Vagal Control of Gastrin Secretion
Holst, Jens Juul, KNUHTSEN, S., Ørskov, Cathrine, SKAK‐NIELSEN, T., Poulsen, Steen Seier & NIELSEN, O. V., 1 Jan 1988, In: Annals of the New York Academy of Sciences. 547, 1, p. 514-515 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of neurotensin from isolated perfused porcine ileum
Holst Pedersen, J., Knuthsen, S., Bernabei, M., Ørskov, Cathrine & Holst, Jens Juul, May 1988, In: Regulatory Peptides. 21, 1-2, p. 13-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Naturally occurring products of proglucagon 111-160 in the porcine and human small intestine
Buhl, T., Thim, L., Kofod, H., Ørskov, Cathrine, Harling, H. & Holst, Jens Juul, 25 Jun 1988, In: Journal of Biological Chemistry. 263, 18, p. 8621-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach
Ørskov, Cathrine, Holst, Jens Juul & Nielsen, O. V., Oct 1988, In: Molecular Endocrinology. 123, 4, p. 2009-13 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretin uncouples glucose inhibition of glucagon-producing cells resulting in a simultaneous stimulation of both glucagon and insulin release
Kofod, H., Holst, Jens Juul & Lernmark, A., Dec 1988, In: Regulatory Peptides. 23, 3, p. 315-22 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1989
- Published
Occurrence, distribution and motor effects of galanin in the porcine lower esophageal sphincter
Holst, Jens Juul & Poulsen, Steen Seier, 1989, In: Digestion. 42, 3, p. 151-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carboxypeptidase-B-like processing of the C-terminus of glucagon-like peptide-2 in pig and human small intestine
Ørskov, Cathrine, Buhl, T., Rabenhøj, L., Kofod, H. & Holst, Jens Juul, 24 Apr 1989, In: F E B S Letters. 247, 2, p. 193-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans
Schjoldager, B. T., Mortensen, P. E., Christiansen, J., Ørskov, Cathrine & Holst, Jens Juul, May 1989, In: Digestive Diseases and Sciences. 34, 5, p. 703-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the regulatory functions of neuropeptide Y (NPY) with respect to vascular resistance and exocrine and endocrine secretion in the pig pancreas
Holst, Jens Juul, Ørskov, Cathrine, Knuhtsen, S., Sheikh, S. & Nielsen, O. V., Aug 1989, In: Acta Physiologica Scandinavica. 136, 4, p. 519-26 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Complete sequences of glucagon-like peptide-1 from human and pig small intestine
Ørskov, Cathrine, Bersani, M., Johnsen, A. H., Højrup, P. & Holst, Jens Juul, 5 Aug 1989, In: The Journal of Biological Chemistry. 264, 22, p. 12826-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Release of PYY from pig intestinal mucosa; luminal and neural regulation
Sheikh, S. P., Holst, Jens Juul, Ørskov, Cathrine, Ekman, R. & Schwartz, Thue W., Dec 1989, In: Regulatory Peptides. 26, 3, p. 253-66 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1990
- Published
Galanin: distribution and effect on contractile activity and release of vasoactive intestinal polypeptide from the isolated perfused porcine ileum
Poulsen, Steen Seier & Holst, Jens Juul, 1990, In: Digestion. 47, 4, p. 191-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Galanin: Distribution and Effect on Contractile Activity and Release of Vasoactive Intestinal Polypeptide from the Isolated Perfused Porcine Ileum
Harling, H., Gregersen, H., Rasmussen, T. N., Holst, Jens Juul & Poulsen, S. S., 1990, In: Digestion. 47, p. 191-199Research output: Contribution to journal › Journal article › Research › peer-review
- 1991
- Published
10.Differences in the control of somatostatin release from antrum and fundus
Holst, Jens Juul, 1991, The Stomach as an Endocrine Organ. Amsterdam: Aspen Publishers, p. 139-149Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
7 Heterogeneity of Islet Hormones
Holst, Jens Juul, Ørskov, C. & Bersani, M., 1991, The Endocrine Pancreas. New York: Raven Press, p. 125-152Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Assays for Peptide Products of Somatostatin Gene Expression
Holst, Jens Juul & Bersani, M., 1991, In: Methods in Neurosciences. 5, p. 3-22Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C-cell hyperplasia accompanying thyroid diseases other than medullary carcinoma: an immunocytochemical study by means of antibodies to calcitonin and somatostatin
Scopsi, L., di Palma, S., Ferrari, C., Holst, Jens Juul & Rehfeld, J. F., 1991, In: Modern Pathology. Vol 4, no.3, p. 297-304Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chap.10. Degradation of glucagons
Holst, Jens Juul, 1991, Degradation of Bioactive Substances: Physiology and Pathophysiology. Boca Raton, Florida: CRC Press, p. 167-180Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Characterization of immunoactive pancreastatin in porcine tissues
Børglum, T. D., Holst, Jens Juul & Fahrenkrug, J., 1991, In: Scand. J. Clin. Lab. Invest.. 51, p. 681-691Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Emptying of the Gastric Substitute, Glucagon-like Peptide-1 (GLP-1), and Reactive hypoglycemia after Total Gastrectomy
Miholic, J., Ørskov, C., Holst, Jens Juul, Kotzerke, J. & Meyer, H. J., 1991, In: Digestive Diseases and Sciences. 36, no.10, p. 1361-1370Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Galanin and galanin extended at the N-terminus with 7 and 9 amino acids are produced in and secreted from the porcine adrenal medulla in almost equal amounts
Bersani, M., Thim, L., Rasmussen, T. N. & Holst, Jens Juul, 1991, In: Endokrinologiya. 129, p. 2693-2698Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Galanin and vasoactive intestinal polypeptide: coexistence and corelease from the vascularly perfused pig ileum during distension and chemical stimulation of the mucosa
Harling, H., Messell, T., Poulsen, Steen Seier & Holst, Jens Juul, 1991, In: Digestion. 50, 2, p. 61-71 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Galanin and vasoactive intestinal polypeptide: Release during intraluminal, chemical irritation and distension of the isolated perfused porcine ileum
Harling, M., Messel, T., Holst, Jens Juul & Poulsen, S. S., 1991, In: Digestion. 50, p. 61-71Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1), Entleerung des Magenersatzes und das Dumpingsyndrom nach Gastrektomie
Miholic, J., Ørskov, C., Holst, Jens Juul, Meyer, H. & Pichlmayr, R., 1991, In: Langerbecks Archiv für Chirurgie. (108. Kongress der Deutsch.Gesellsch.Chirurgie. Suppl.1991, p. 430-432Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human galanin: primary structure and identification of two molecular forms
Bersani, M., Johnsen, A. H., Højrup, P., Dunning, B. E., Holst, Jens Juul & Andreasen, J. J., 1991, In: FEBS Letters. 283, p. 189-194Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification, characterization and release of GRP gene-associated peptides from the normal porcine and human gastro-intestinal tract
Bjørnskov-Bartholdy, L., Bersani, M. & Holst, Jens Juul, 1991, In: Regulatory Peptides. 34, p. 197-209Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of peptides on anorectal function
Christiansen, J., Lorentzen, M. & Holst, Jens Juul, 1991, In: Annals of Medicine. 22, p. 413-418Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of short term verapamil treatment on glucose metabolism in patients with non-insulin dependent diabetes mellitus
Busch Sørensen, M., Sjøstrand, H., Holst, Jens Juul, Sengeløv, H., Tiefenthal Thrane, M. & Lyngsøe, J., 1991, In: EUR. J. Clin. Pharmacol.. 41, p. 401-404Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nerve fibers in the rat posterior pituitary lobe contain Prosomatostatin (1-64)
Mikkelsen, J. D., Bersani, M., Holst, Jens Juul & Larsen, P. J., 1991, In: Neuroendocrinology. 54, p. 469-476Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuropeptide Y (NPY) and vasoactive intestinal polypeptide (VIP), but not galanin, are autonomic cotransmitters in the porcine pancreas
Messell, T., Dunning, B. E., Sheikh, S. & Holst, Jens Juul, 1991, In: International Journal of Gastrointestinal Cancer. 10, p. 133-141Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidation/reduction explains heterogeneity of pancreatic somatostatin
Bersani, M., Johnsen, A. H. & Holst, Jens Juul, 1991, In: FEBS Letter. 279, no.2, p. 237-239Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma glucagon and glucose recovery after hypoglycemia: The effect of total autonomic blockade
Hilsted, J., Frandsen, H., Holst, Jens Juul, Christensen, J. & Nielsen, S. L., 1991, In: Acta Endocrinol.. 125, p. 466-469Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting-state and after oral glucose and intravenous arginine
Ørskov, C., Jeppesen, J., Madsbad, J. & Holst, Jens Juul, 1991, In: J. Clin. Invest.. 87, p. 415-423Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Release of galanin from isolated, perfused porcine adrenal glands. Role of the splanchnic nerves
Holst, Jens Juul, Ehrhart-Bornstein, M. & Messell, T., 1991, In: Amer.J. Physiology. 261, p. E31-E40Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of classical and peptidergic neurotransmitters in insulin secretion
Holst, Jens Juul, 1991, Nutrient Regulation of Insulin Secretion. Portland PressResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Substance P and Neurokinin A are Codistributed and Colocalized in the Porcine Gastrointestinal Tract
Schmidt, P., Poulsen, S. S., Rasmussen, T. N., Bersani, M. & Holst, Jens Juul, 1991, In: Peptides. 12, p. 963-973Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substance P and neurokinin A are codistributed and colocalized in the porcine gastrointestinal tract
Poulsen, Steen Seier, Bersani, M., Holst, Jens Juul, Schmidt, P. & N. Rasmussen, T., 1991, In: Peptides. 12, 5, p. 963-73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vasoactive intestinal peptide in the porcine adrenal gland
Ehrhart-Bornstein, M., Bornstein, S. R. & Holst, Jens Juul, 1991, In: Neuroendocrinology. 54, p. 623-628Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential Effects of Secretin-fragments imply a dual Mechanism of Action for Secretin
Kofod, H., Thams, P. & Holst, Jens Juul, Feb 1991, In: International Journal of Peptide and Protein Research. 37, 2, p. 134-139 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine
Ørskov, Cathrine, Jeppesen, J., Madsbad, Sten & Holst, Jens Juul, Feb 1991, In: The Journal of Clinical Investigation. 87, 2, p. 415-23 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastrin-releasing peptide is a transmitter mediating porcine gallbladder contraction
Schjoldager, B., Poulsen, S. S., Schmidt, P., Coy, D. H. & Holst, Jens Juul, Apr 1991, In: American Journal of Physiology (Consolidated). 260, 4 Pt 1, p. G577-85Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Release of galanin from isolated perfused porcine adrenal glands: role of splanchnic nerves
Holst, Jens Juul, Ehrhart-Bornstein, M., Messell, T., Poulsen, Steen Seier & Harling, H., Jul 1991, In: American Journal of Physiology (Consolidated). 261, 1 Pt 1, p. E31-E40Research output: Contribution to journal › Journal article › Research › peer-review
- 1992
- Published
All products of proglucagon are elevated in plasma from ureamic patients
Ørskov, Cathrine, Andreasen, J. & Holst, Jens Juul, 1992, In: Journal of Clinical Endocrinology and Metabolism. 79, p. 379-383Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetogenic Effect of glucagon-like peptide-1 (7-36) amide in normal subjects and patients with diabetes mellitus
Gutniak, M., Ørskov, Cathrine, Holst, Jens Juul, Ahrén, B. & Efendic, S., 1992, In: New England Journal of Medicine. 326, p. 1316-1322Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating galanin: origin, metabolism, and pharmacokinetics in anesthetized pigs
Harling, H. & Holst, Jens Juul, 1992, In: Am. J. of Physiology. 262, p. E52-E57Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution and characterization of different molecular products of Pro-somatostatin in the hypothalmus and posterior pituitary lobe of the mongolian gerbil (Meriones unguiculatus)
Larsen, P. J., Bersani, M., Holst, Jens Juul, Møller, M. & Mikkelsen, J. D., 1992, In: Journal of Neuroscience. 12, hæfte 3, p. 946-961Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of chemical myenteric ablation on the structure proliferation and endocrine cells in the small intestinal mucosa
Holle, G. E., Demir, I., Dietl, J., Rehfeld, J. F. & Holst, Jens Juul, 1992, Advances in the Innervation of the Gastrointestinal Tract. Aspen PublishersResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Effects of oleic acid and endogenous bile on the duodenal secretion of somatostatin in man
Olsen, O., Holst, Jens Juul & Schaffalitzky de Muckadell, O. B., 1992, In: Dig. Diseases and Sciences. 37(7), p. 1025-1028Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extrinsic control of the release of galanin and VIP from intrinsic nerves of isolated, perfused porcine ileum
Messel, T., Harling, H., Poulsen, S. S., Bersani, M. & Holst, Jens Juul, 1992, In: Regulatory Peptides. 38, p. 179-198Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon immunoneutralization in diabetic rats normalizes urea synthesis and decreases nitrogen wasting
Almdal, T. P., Holst, Jens Juul & Vilstrup, H., 1992, In: Diabetes. 41, p. 12-16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 - a new hormone which may change the treatment of non-insulin dependent diabetes mellitus
Holst, Jens Juul & Ørskov, C., 1992, In: MedView. 6, p. 259-263Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunohistochemical localization of pancreatic spasmolytic polypeptide in the pig
Rasmussen, T. N., Raaberg, L., Poulsen, S. S., Thim, L. & Holst, Jens Juul, 1992, In: Histochemistry. 98, p. 113-119Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nervous control of the release of substance P and neurokinin A from the isolated perfused porcine ileum
Schmidt, P., Rasmussen, T. N. & Holst, Jens Juul, 1992, In: J. of the Autonomic Nerv. System. 38, p. 85-96Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proglucagon products in plasma of uraemic patients and normals in the fasting state
Ørskov, C., Andreasen, J. & Holst, Jens Juul, 1992, In: J. Clin. Endocrinol. Metab.. 74, p. 379-384Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Somatostatin is an essential paracrine link in acid inhibition of gastrin secretion
Holst, Jens Juul, Ørskov, Cathrine & Poulsen, S. S., 1992, In: Digestion. 51, p. 95-102Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Somostatin and Prosomatostatin-immunoreactive nerve fibers in the bovine pineal gland
Møller, M., Mikkelsen, J. D. & Holst, Jens Juul, 1992, In: Neuroendocrinology. Vol. 56 (2), p. 278-283Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vagal control of the release of somatostatin, vasoactive intestinal polypeptide, gastrin releasing peptide and HC1 from porcine non-antral stomach
Holst, Jens Juul, Skak-Nielsen, T., Ørskov, C. & Poulsen, S. S., 1992, In: Scandinavian Journal of Gastroenterology. 27, p. 677-685Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extrinsic control of the release of galanin and VIP from intrinsic nerves of isolated, perfused, porcine ileum
Messell, T., Harling, H., Poulsen, Steen Seier, Bersani, M. & Holst, Jens Juul, 9 Apr 1992, In: Regulatory Peptides. 38, 3, p. 179-98 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vagal control of the release of somatostatin, vasoactive intestinal polypeptide, gastrin-releasing peptide, and HCl from porcine non-antral stomach
Holst, Jens Juul, Skak-Nielsen, T., Ørskov, Cathrine & Seier-Poulsen, S., Aug 1992, In: Scandinavian Journal of Gastroenterology. 27, 8, p. 677-85 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunohistochemical localization of pancreatic spasmolytic polypeptide (PSP) in the pig
Raaberg, L., Poulsen, Steen Seier, Thim, L. & Holst, Jens Juul, Sep 1992, In: Histochemistry. 98, 2, p. 113-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1993
- Published
Biological effects and metabolic rates of GLP-1 7-36 amide and GLP-1 7-37 in healthy volunteers are indistinguishable
Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, 1993, In: Diabetes. 42, p. 658-661Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calcitonin gene-related peptide: effect on contractile activity and luminal-cross-sectional area in isolated, perfused porcine ileum
Rasmussen, T. N., Gregersen, H., Harling, H. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 27, p. 787-792Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebrovascular changes following administration of gammaglobulins against substance P or calcitonin gene related peptide in monkey with subarachnoid haemorrhage
Shiokawa, Y., Holst, Jens Juul, Rasmussen, J. T. N., Schmidt, P. & Svendgaard, N., 1993, In: British J. of Neurosurgery. 7, p. 507-518Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of chemical myenteric ablation on the structure, proliferation and endocrine cells in the small intestinal mucosa
Holle, G. E., Demir, I., Dietl, J., Forssmann, W. G., Rehfeld, J. F. & Holst, Jens Juul, 1993, In: Advances in the Innervation of the Gastrointestinal Tract. p. 89-98Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of glucagon immunoneutralization on the increase in urea synthesis after hysterectomy in rats
Heindorff, H., Holst, Jens Juul, Almdal, T. P. & Vilstrup, H., 1993, In: European Journal of Clinical Investigation. 23, p. 166-170Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of intestinal inhibitory peptides on vagally induced secretion from isolated perfused porcine pancreas
Holst, Jens Juul, Rasmussen, T. N., Harling, H. & Schmidt, P., 1993, In: Pancreas. Vol. 8, no. 1, p. 80-87Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 - et nyt hormon med mulig anvendelse i diabetesbehandlingen
Holst, Jens Juul, 1993, In: Tidsskrift for Diabetesbehandling. 3, p. 33-39Research output: Contribution to journal › Journal article › Research
- Published
Neural regulation of pancreatic exocrine funktion
Holst, Jens Juul, 1993, In: The Pancreas: Biology, Pathobiology an Disease. p. 381-402Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuromediators in the control of pancreatic secretion
Holst, Jens Juul, 1993, Neuromediators in the control of pancreatic secretion. Torun: Polish Physiological Society, p. 72-78Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Normalization of fasting hyperglycaemia by exogenous-glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients
Nauck, M. A., Kleine, N., Ørskov, C., Holst, Jens Juul, Willms, B. & Creutzfeldt, W., 1993, In: Diabetologia. 36, p. 741-744Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the effects of human galanin in man
Holst, Jens Juul, Bersani, M., Hvidberg, A., Knigge, Ulrich, Christiansen, E. M., Madsbad, Sten, Harling, H. & Kofod, H., 1993, In: Diabetologia. 36, 7, p. 653-657 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreas and gut hormone responses to oral glucose and intravenous glucagon in cystic fibrosis patients with normal, impaired and diabetic glucose tolerance
Laang, S., Thorsteinsson, B., Røder, M. E., Ørskov, Cathrine, Holst, Jens Juul, Nerup, J. & Koch, C., 1993, In: Acta Endoctrinologica. 128, p. 207-214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial release of glucagon-like peptide-1, pancreatic glucagon, and insulin after esophageal resection
Miholic, J., Ørskov, C., Holst, Jens Juul, Kotzerke, J. & Pichlmayr, R., 1993, In: Digestion. 54, p. 73-78Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved incretin activity of glucagon-like peptide 1 (7-36 amide) but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus
Nauck, M. A., Heimesaat, M. M., Ørskov, C., Holst, Jens Juul, Ebert, R. & Creutzfeldt, W., 1993, In: Journal of Clinical Investigation. 91, p. 301-307Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of secretion of pancreatic spasmolytic polypeptide from porcine pancreas
Rasmussen, T. N., Harling, H., Thim, L., Pierzynowski, S., Weström, B. R. & Holst, Jens Juul, 1993, In: The American Journal of Physiology. p. G22-G29Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Release of immunoreactive somatostatin, vasoactive intestinal polypeptide (VIP), and galanin during propulsive complexes in isolated pig ileum
Schmidt, P., Rasmussen, T. N. & Holst, Jens Juul, 1993, In: Peptides. Vol. 14, p. 215-220Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dissociation of tumor-induced weight loss from hypoglycemia in a transplantable pluripotent rat islet tumor results in the segregation of stable *Ga- and *Gb-cell tumor phenotypes
Madsen, O. D., Karlsen, G., Nielsen, E., Lund, K., Kofod, H., Welinder, B., Rehfeld, J. F., Larsson, L., Steiner, D. F., Holst, Jens Juul & Michelsen, B. K., 1993, In: Endokrinologiya. vol. 133, no. 5, p. 2022-2030Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of glucose on the plasma concentration of somatostatin during caloric deficiency in man
Øktedalen, O., Opstad, P. K. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 28, p. 652-656Research output: Contribution to journal › Journal article › Research
- Published
Transmitters in the control of gastrin and acid secretion in the pig stomach
Holst, Jens Juul, Nørre Ramussen, T., Schmidt, P. & Poulsen, S. S., 1993, Gastrin. New York: Raven Press, p. 243-258Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man
Wettergren, A., Schjoldager, B., Mortensen, P. E., Myhre, J., Christiansen, J. & Holst, Jens Juul, 1993, In: Digestive Diseases and Sciences. Vol. 38, no. 4, p. 665-673Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vasoactive intestinal peptide (VIP) stimulates androstenedione release in isolated perfused pig adrenals
Bornstein, S. R., Ehrhart-Bornstein, M., Stromeyer, H. G., Adler, G., Scherbaum, W. A. & Holst, Jens Juul, 1993, In: Life Sciences. 52, p. 135-140Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biological effects and metabolic rates of glucagonlike peptide-1 7-36 amide and glucagonlike peptide-1 7-37 in healthy subjects are indistinguishable
Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, May 1993, In: Diabetes. 42, 5, p. 658-61 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dissociation of tumor-induced weight loss from hypoglycemia in a transplantable pluripotent rat islet tumor results in the segregation of stable alpha- and beta-cell tumor phenotypes
Madsen, O. D., Karlsen, C., Nielsen, E., Lund, K., Kofod, H., Welinder, B., Rehfeld, Jens Frederik, Larsson, L. I., Steiner, D. F. & Holst, Jens Juul, Nov 1993, In: Endocrinology. 133, 5, p. 2022-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
- Published
Atrial natriuretic peptide-like immunoreactive material (ANP-L1) is released from the adrenal gland by splanchnic nerve stimulation
Duntas, L., Bornstein, S. R., Scherbaum, W. & Holst, Jens Juul, 1994, In: Exp.Clin.Endocrinol.. 101, p. 371-373Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholecystokinin is a negative regulator of gastric acid secretion and postprandial release of gastrin in humans.
Schmidt, W. E., Schenk, S., Nustede, R., Rovati, L. C., Holst, Jens Juul, Fölsch, U. & Creutzfeldt, W., 1994, In: Today in Medicine. Gastroenterology. 107, p. 1610-1620Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Decreased postprandial thermogenesis and fat oxidation, but increased fullness after a high-fiber meal compared to a low-fiber meal
Raben, A. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Clin. Nutr.. 59, p. 1386-1394Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of glucagon-like peptide-1 (proglucagon 78 - 107 amide) on hepatic glucose production in healthy man
Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, 1994, In: Metabolism. 43, p. 104-108Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of glucagon-like peptide-1 (proglucagon 78-107 amide) on hepatic glucose production in healthy man
Hvidberg, A., Nielsen, M. T., Hilsted, J., Holst, Jens Juul & Ørskov, C., 1994, In: Metabolism. 43, p. 104-108Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity
Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Physiol.. 267, p. E549-E559Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence for an abnormal postprandial response to a high-fat meal in women predisposed to obesity
Raben, Anne, Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, In: American Journal of Physiology: Endocrinology and Metabolism. 267, 4 part 1, p. E549-E559 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exendin-4 and exendin (9-39)NH*U2-agonist and antagonist, respectively, at the rat parietal cell receptor for glucagon-like peptide-1 (7-36)NH*U2
Schepp, W., Schmidtler, J. & Holst, Jens Juul, 1994, In: Eur. J. Pharmacol.. 269, p. 183-191Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon and other proglucagon-derived peptides
Holst, Jens Juul & Ørskov, Cathrine, 1994, Gut Peptides: Biochemistry and Physiology. New York: Raven Press, p. 305-340Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Glucagon-like peptide 1: on its way to clinical application
Göke, B., Göke, R., Holst, Jens Juul & Ørskov, C., 1994, In: Digestion. 54, p. 339-340Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1) - A newly discovered Gl Hormone. Review.
Holst, Jens Juul, 1994, In: Today in Medicine. Gastroenterology. 107, p. 1848-1855Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1) 7-36 amide and peptide YY from L-cell in the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man
Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. & Holst, Jens Juul, 1994, In: Scandinavian Journal of Gastroenterology. 29, p. 501-505Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut hormones and intestinal function
Holst, Jens Juul & Schmidt, P., 1994, The Gut as an Endocrine Organ. Clinics in Endocrinology and Metabolism, Vol 8. Bailliere, p. 137-164Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Immunoneutralization of endogenous glucagon with monoclonal glucagon antibody normalizes hyperglycemia in moderately streptozotocin-diabetes rats
Brand, C. L., Rolin, B., Jørgensen, P. N., Svendsen, J. S. & Holst, Jens Juul, 1994, In: Diabetologia. 37, p. 985-993Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolated organs as replacements for vertebrate animals
Holst, Jens Juul, 1994, Handbook of Laboratory Animal Science. USA: CRC Press, p. 397-408Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Nitric oxide (NO) is an important element in neurally induced pancreatic exocrine secretion in pigs
Holst, Jens Juul, Rasmussen, T. N. & Schmidt, P., 1994, In: Am J Physiology. 29, p. G206-G213Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptidergic control of amylase secretion from the rat parotid gland
Goll, R., Poulsen, J. H., Schmidt, P., Schjoldager, B., Poulsen, S. S. & Holst, Jens Juul, 1994, In: Regulatory Peptides. 51, p. 237-254Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pigs produce only a single form of CGRP, part of which is processed to N- and C-terminal fragments
Rasmussen, T. N., Bersani, M., Johnsen, A. H., Kofod, H. & Holst, Jens Juul, 1994, In: Peptides. 15, 1, p. 89-94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial lipid oxidation reduced and carbohydrate oxidation increased in postobese subjects
Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, Obesity in Europe. John Libbey, p. 135-137Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Production and secretion of amidated and glycine-extended glucagon-like peptide-1 (GLP) in man
Ørskov, C., Rabenhøj, L., Kofod, H., Wettergren, A. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-39Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proglucagon processing in porcine and human pancreas
Holst, Jens Juul, Bersani, M., Johnsen, A. H., Kofod, H., Hartmann, Bolette & Ørskov, Cathrine, 1994, In: Journal of Biological Chemistry. 269, 29, p. 18827-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rat parietal cell receptors for GLP-1 (7-36) amide: Northern blot, cross-linking, and radioligand binding
Schmidtler, J., Dehne, K., Allescher, H. D., Schusdziarra, V., Classen, M., Holst, Jens Juul, Polack, A. & Schepp, W., 1994, In: Am. J. Physiol.. 267, p. G423-G432Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resistant starch: The effect on postprandial glycemia, hormonal response and satiety
Raben, A., Tagliabue, A., Christensen, N. J., Madsen, J. J. V., Holst, Jens Juul & Astrup, A., 1994, In: Am. J. Clin. Nutr.. 60, p. 544-551Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of glucagon-like peptide-1 and reactive hypoglycemia after partial gastrectomy
Andreasen, J., Ørskov, Cathrine & Holst, Jens Juul, 1994, In: Digestion. 55, p. 221-228Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of pancreastatins from isolated, perfused porcine adrenal glands
Børglum, T., Fahrenkrug, J. & Holst, Jens Juul, 1994, In: Peptides. 15, p. 519-527Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of pancreastatins from the porcine gastrointestinal tract
Børglum, J. T., Holst, Jens Juul & Fahrenkrug, J., 1994, In: Scandinavian Journal of Gastroenterology. 29, p. 376-384Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subcutaneous injection of glucagon-like insulintropic peptide reduces postprandial glycemia in non-insulin dependent diabetes
Gutniak, M. K., Linde, B., Holst, Jens Juul & Efendic, S., 1994, In: Diabetes Care. 17, p. 1039-1044Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sympathoadrenal regulation of adrenal androstenedione release
Ehrhart-Bornstein, M., Bornstein, S. R., Behling, H. G., Holst, Jens Juul, Strohmayer, H. G., Rasmussen, T. N., Scherbaum, W. A. & Adler, G., 1994, In: Neuroendocrinology. 59, p. 406-412Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide-1 in humans
Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-539Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of glucagon-like peptide-1 (proglucagon 78-107amide) on hepatic glucose production in healthy man
Hvidberg, A., Nielsen, M. T., Hilsted, J., Ørskov, Cathrine & Holst, Jens Juul, Jan 1994, In: Metabolism. 43, 1, p. 104-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans
Ørskov, Cathrine, Rabenhøj, L., Wettergren, A., Kofod, H. & Holst, Jens Juul, Apr 1994, In: Diabetes. 43, 4, p. 535-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptide-evoked release of amylase from isolated acini of the rat parotid gland
Goll, R., Poulsen, J. H., Schmidt, P., Schjoldager, B., Poulsen, Steen Seier & Holst, Jens Juul, 26 May 1994, In: Regulatory Peptides. 51, 3, p. 237-54 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man
Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. P. & Holst, Jens Juul, Jun 1994, In: Scandinavian Journal of Gastroenterology. 29, 6, p. 501-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calcitonin gene-related peptide (CGRP) in the nipple of the rat mammary gland
Thulesen, J., Rasmussen, T. N., Schmidt, P., Holst, Jens Juul & Poulsen, Steen Seier, Dec 1994, In: Histochemistry. 102, 6, p. 437-444 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1995
- Published
Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.
Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In: Diabetes. 44, p. 1126-1131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of sandwich ELISA and RIA for determination of exogenous GLP-1 (7-36 amide) in plasma.
Pridal, L., Ingwersen, S. H., Larsen, F. S., Holst, Jens Juul, Adelhorst, K. & Kirk, O., 1995, In: J Pharmaceutical and Biomedical Analysis. 13, p. 841-850Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo.
Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, p. 952-957Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of 17-norleucine-VIP on gastroduodenal motility relative to serum VIP concentration and blockade of NOS.
Holle, G. E., Steinbach, E., Wünsch, E. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. G584-G590Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of endogenous hypergastrinemia on gastrin receptor expressing human colon carcinoma transplanted to athymic rats.
Chu, M., Franzén, L., Rehfeld, J. F., Holst, Jens Juul & Borch, K., 1995, In: Today in Medicine. Gastroenterology. 109, p. 1415-1420Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus.
Hannibal, J., Mikkelsen, J. D., Clausen, H., Holst, Jens Juul, Wulff, B. S. & Fahrenkrug, J., 1995, In: Regulatory Peptides. 55, p. 133-148Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 (7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using a-glucosidase inhibition (acarbose)
Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 (GLP-1)(7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using alpha-glucosidase inhibition (acarbose).
Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, C. & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histochemical, pharmacological, biochemical and chromatographic evidence that pituitary adenylyl cyclase activating peptide is involved in inhibitory neurotransm.in the taenia of the guinea-pig caecum
McConalogue, K., Furness, J. B., Vremec, M. A., Holst, Jens Juul, Tornøe, K. & Marley, P. D., 1995, In: J. Autonom Nerv. System. 50, p. 311-322Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Glucagon-like peptide-1, - six important topics.
Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System.. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 537-546Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Human colon produces fully processed glucagon-like peptide-1 (7-36 amide).
Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: FEBS Letters. 372, p. 269-272.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ileal release of glucagonlike peptide-1 (GLP-1): association with inhibition of gastric acid in humans
Layer, P., Holst, Jens Juul, Grandt, D. & Goebell, H., 1995, In: Digestive Disease Science. 40, p. 1074-82Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increases in plasma motilin follow each episode of gallbladder emptying during the interdigestive period and changes in serum bile acid concentration correlate to plasma motilin.
Qvist, N., Øster-Jørgensen, E., Pedersen, S. A., Rasmussen, L., Hovendal, C. & Holst, Jens Juul, 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 122-127Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulintropic actions of intravenous glucagon-like peptide-1 (GLP-1) (7-36 amide) in the fasting state in healthy subjects
Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Acta Diabetologica. 32, p. 13-16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacokinetic, insulinotropic and glucagonostatic properties of GLP-1 (7-36 amide) after subcutaneous injection in healthy volunteers. Dose-response-relationships
Ritzel, R., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., 1995, In: Diabetologia. 38, p. 720-725Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8
Fieseler, P., Bridenbaugh, S., Nustede, R., Martell, J., Nauck, M. A., Ørskov, Cathrine & Holst, Jens Juul, 1995, In: Am. J. Physiol.. Vol 268, p. E949-E955Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial glucagon-like peptide-1 (GLP-1) release in states of normal and disturbed luminal nutrient digestion.
Layer, P., v d Ohe, M. & Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 547-550Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Potent inhibitory effects of transplantable rat glucagonomas and insulinomas on the respective endogenous islet cells are associated with pancreatic apoptosis.
Blume, N., Skouv, J., Larsson, L., Holst, Jens Juul & Madsen, O. D., 1995, In: J. Clin. Invest.. 96, p. 2227-2235Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Presence of somatostatin containing neuronal-like cells in the rat pineal gland.
Møller, M., Holst, Jens Juul, Mikkelsen, J. D. & Webb, S., 1995, In: Neuroendocrinol. Letters. 17, p. 71-80Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion and effects of glucagon-like peptide-1 (GLP-1) in healthy volunteers and NIDDM subjects.
Ørskov, C. & Holst, Jens Juul, 1995, Diabetes 1994. Elsevier Sci. Intl. Congress Series 1100, p. 513-516Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Sympathoadrenal regulation of adrenocortical steroidogenesis
Ehrhart-Bornstein, M., Bornstein, S. R., Gonzalez-Hernandez, J., Holst, Jens Juul, Watermann, M. R. & Scherbaum, W. A., 1995, In: Endocrine Research. 21, p. 13-24Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of glucagon in the maintenance of euglycemia in the fed and the fasted state. Monoclonal antibody treatment as a tool in glucagon physiology in rats.
Brand, C. L., Jørgensen, P. N., Svendsen, I., Kristensen, J. S., Knigge, U., Warberg, J. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. E469-E477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transplantable glucagonomas derived from pluripotent rat islet tumor tissue cause severe anorexia and adipsia
Madsen, O. D., Karlsen, C., Blume, N., Jensen, H. I., Larsson, L. & Holst, Jens Juul, 1995, In: Scand. J. Clin. Lab. Invest.. 55, suppl. 220, p. 27-36Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
Gastrin release in the fetal lamb in response to luminal infusion of amniotic fluid, milk or GRP
Sangild, Per Torp, Hilsted, L., Bjørnskov-Bartholdy, L., Holst, Jens Juul & Trahair, J. F., 1996. 1 p.Research output: Contribution to conference › Paper › Research
- Published
Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients: dose-response effects of insulin on glucose turnover
Christiansen, E., drb459, drb459, Tibell, A., Hother-Nielsen, O., Holst, Jens Juul, Pedersen, O. & Madsbad, Sten, 1996, In: Diabetes. 45, 9, p. 1267-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Positive effects on plasma glucose & appetite by industrial modification of starch
Raben, A., Andersen, K., Karberg, M. A., Holst, Jens Juul & Astrup, A., 1996. 1 p.Research output: Contribution to conference › Poster › Research
- Published
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
Willms, B., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Nauck, M. A., Jan 1996, In: Endocrinology. 81, 1, p. 327-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Release of glucagon-like peptide 1 (GLP-1 [7-36 amide]), gastric inhibitory polypeptide (GIP) and insulin in response to oral glucose after upper and lower intestinal resections
Nauck, M. A., Siemsglüss, J., Ørskov, Cathrine & Holst, Jens Juul, Mar 1996, In: Zeitschrift fur Gastroenterologie. 34, 3, p. 159-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
Ørskov, Cathrine, Poulsen, Steen Seier, Møller, Morten & Holst, Jens Juul, Jun 1996, In: Diabetes. 45, 6, p. 832-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients
Creutzfeldt, W. O., Kleine, N., Willms, B., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., Jun 1996, In: Diabetes Care. Supplement. 19, 6, p. 580-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of the incretin hormones glucagon-like peptide-1 and gastric inhibitory polypeptide correlates with insulin secretion in normal man throughout the day
Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, Jul 1996, In: Scandinavian Journal of Gastroenterology. 31, 7, p. 665-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1
Serup, P., Jensen, J., Andersen, F. G., Jørgensen, Mette Christine, Blume, N., Holst, Jens Juul & Madsen, O. D., 20 Aug 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 17, p. 9015-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 does not not acutely affect insulin sensitivity in healthy man
Orskov, L., Holst, Jens Juul, Møller, J., Ørskov, Cathrine, Møller, N., Alberti, K. G. & Schmitz, O., Oct 1996, In: Diabetologia. 39, 10, p. 1227-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tachykinins mediate vagal inhibition of gastrin secretion in pigs
Schmidt, P., Poulsen, Steen Seier, Hilsted, Linda, Rasmussen, T. N. & Holst, Jens Juul, Oct 1996, In: Gastroenterology. 111, 4, p. 925-35 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM
Nauck, M. A., Wollschläger, D., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Willms, B., Dec 1996, In: Diabetologia. 39, 12, p. 1546-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the effects of glucagon-like peptide-1 on blood glucose regulation in normal and diabetic subjects
Holst, Jens Juul, Toft-Nielsen, M. B., Ørskov, Cathrine, Nauck, M. & Willms, B., 26 Dec 1996, In: Annals of the New York Academy of Sciences. 805, p. 729-36 8 p.Research output: Contribution to journal › Review › Research › peer-review
- 1997
- Published
A double-blind placebo-controlled study on the effects of omeprazole on gut hormone secretion and gastric emptying rate.
Rasmussen, L., Qvist, N., Øster-Jørgensen, E., Rehfeld, J. F., Holst, Jens Juul & Pedersen, S. A., 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 900-905Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered postprandial motility in chronic pancreatitis: role of malabsorption.
Layer, P., v.d. Ohe, M. R., Grandt, D., Holst, Jens Juul, Jansen, J. B. M. J., Holtmann, G., Keller, J. & Goebell, H., 1997, In: Today in Medicine. Gastroenterology. 112, p. 1624-1634Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bombesin inhibits histamine release from the rat oxyntic mucosa by a somatostatin-dependent mechanism.
Sandvik, A. K., Brenna, E., Sundan, A., Holst, Jens Juul & Waldum, H. L., 1997, In: Scandinavian Journal of Gastroenterology. 30, p. 427-432Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating GRP and gastrin in fetal lambs in response to luminal infusion of fluids
Sangild, Per Torp, Hilsted, L., Bjørnskov-Bartholdy, L., Holst, Jens Juul & Trahair, J. F., 1997.Research output: Contribution to conference › Paper › Research
- Published
Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.
Furuta, M., Yano, H., Zhou, A., Rouille, Y., Holst, Jens Juul, Carroll, R., Ravazzolla, M., Orci, L. & Steiner, D. F., 1997, In: Proc. Natl. Acad. Sci.. 94, p. 6646-6651Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem
Larsen, P. J., Tang-Christensen, M., Holst, Jens Juul & Ørskov, Cathrine, 1997, In: Neuroscience. Vol. 77, No. 1, p. 257-270Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of GLP-1 on gastric and pancreatic exocrine secretion and on gastrointestinal motility.
Nauck, M. A., Schepp, W., Holst, Jens Juul & Schmiegel, W. H., 1997, The Insulintropic Gut Hormone Glucagon-Like Peptide-1, Front Diabetes vol. 13. Basel: Karger, p. 194-206Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Effects of glucagon-like peptide-1 (7-36amide) on whole body protein metabolism in healthy man.
Shalev, A., Holst, Jens Juul & Keller, U., 1997, In: European Journal of Clinical Investigation. 27, p. 10-16.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of glucagon-like peptide-1 on islet function and insulin sensitivity in non-insulin dependent diabetes mellitus.
Ahrén, B., Larsson, H. & Holst, Jens Juul, 1997, In: J. Clin. Endocrinol. Metab.. 82, p. 473-478Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Einfluss von subkutanem GLP-1 auf die frühe und langsame Phase der Insulin-sekretion nach intravenöser Glukosebelastung bei gesunden Probanden.
Ritzelt, R., Ørskov, C., Holst, Jens Juul, Schmiegel, W. & Nauck, M. A., 1997, In: Diabetes und Stoffwechsel. 6, p. 64-69.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteroglucagon
Holst, Jens Juul, 1997, In: Annual Reviews of Physiology. 59, p. 257-272Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP and GLP-1 after oral glucose in postmenopausal women with impaired glucose tolerance.
Ahrén, B., Larsson, H. & Holst, Jens Juul, 1997, In: European Journal of Endocrinology. 137, p. 127-131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastrointestinal hormones and gastric emptying 20 years after jejunoileal bypass for massive obesity.
Näslund, E., Grybäck, P., Hellström, P. M., Jacobsson, H., Holst, Jens Juul, Theodorsson, E. & Backmann, L., 1997, In: International Journal of Obesity. 21, p. 387-392Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1) as a new therapeutic approach for type-2 diabetes.
Nauck, M. A., Holst, Jens Juul, Willms, B. & Schmiegel, W., 1997, In: Exp. Clin. Endocrinol. Diabetes. 105, p. 187-195Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-17-36amide) reduces hepatic glucose production indirectly through changes in insulin and glucagon secretion.
Larsson, H., Holst, Jens Juul & Ahrén, B., 1997, In: Acta Phys. Scand.. 160, p. 413-422Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 7-36amide and peptide YY have additive inhibitory effects on gastric acid secretion in man.
Wettergren, A., Maina, P., Boesby, S. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 552-555Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 promotes satiety and suppresses energy intake in humans
Flint, A., Raben, A., Holst, Jens Juul & Astrup, A., 1997, International journal of obesity. 21 ed. European Association for the Study of Obesity, p. 16 1 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Glucose absorption and the release of insulin, gastric inhibitory polypeptide, and glucagon-like peptide-1 in patients after total colectomy.
Palnæs Hansen, C., Andreassen, J. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 473-477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Holder GLP-1 som nyt terapeutisk princip i diabetesbehandlingen hvad det lovede?
Holst, Jens Juul, 1997, In: Tidsskrift for Diabetesbehandling. 2(7), p. 16-22Research output: Contribution to journal › Journal article › Research
- Published
Metabolism of oral glucose in pancreas transplant recipients with normal and impaired glucose tolerance.
Christiansen, E., Tibell, A., Vølund, A., Holst, Jens Juul, Rasmussen, K., Schäffer, L. & Madsbad, S., 1997, In: J. Clin. Endocrinol. Metab.. 82, p. 2299-2307Research output: Contribution to journal › Journal article › Research
- Published
Non-insulin-dependent diabetes mellitus - new drugs?
Holst, Jens Juul, 1997, In: Drug Discovery Today. 2, p. 128-129Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel Mody3 Mutations in the Hepatocyte Factor-1a Gene. Evidence for a Hyperexcitabillity of Pancreatic ß-cells to Intravenous Secretagogues in a Glucosetolerant Carrier of a P447L Mutation
Hansen, T., Eiberg, Hans Rudolf Lytchoff, Rouard, M., Vaxillaire, M., Møller, A. M., Rasmussen, S. K., Fridberg, M. & Holst, Jens Juul, 1997, In: Diabetes. 46, p. 726-730Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PACAP 1-38 as neurotransmitter in the pig pancreas: PACAP-receptor activation revealed by the antagonist PACAP 6-38.
Tornøe, K., Hannibal, J., Fahrenkrug, J. & Holst, Jens Juul, 1997, In: Am. J. Physiol.. 273, p. G436-G446Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pituitary adenylate-cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans.
Filipson, K., Tornøe, K., Holst, Jens Juul & Ahrén, B., 1997, In: J. Clin. Endocrinol. Metab.. 82, p. 3093-3098Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Posttranslational processing of proglucagon and postsecretory fate of proglucagon products.
Holst, Jens Juul, Ørskov, C., Hartmann, B. & Deacon, Carolyn F., 1997, The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel: Karger, p. 24-48Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Short term insulin treatment prevents the diabetogenic action of streptozotocin in rats
Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 1997, In: Endokrinologiya. Vol. 138, No. 1, p. 62-68Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation.
Wettergren, A., Wøjdemann, M., Meisner, S., Stadil, F. & Holst, Jens Juul, 1997, In: Gut. 40, p. 597-601Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The pathogenesis of non-insulin dependent diabetes mellitus involves a defective expression of the GIP receptor.
Holst, Jens Juul, Gromada, J. L. & Nauck, M. A., 1997, In: Diabetologia. 40, p. 984-986Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The release of gastric inhibitory peptide, glucagon-like peptide-1, and insulin after oral glucose test in colectomized subjects.
Palnæs Hansen, C., Andreassen, J. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 473-477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of antagonists to define tachykininergic control of intestinal motility in pigs.
Schmidt, P. & Holst, Jens Juul, 1997, In: Peptides. 18, p. 373-379Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term insulin treatment prevents the diabetogenic action of streptozotocin in rats
Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Jan 1997, In: Endocrinology. 138, 1, p. 62-68 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans
Nauck, M. A., Niedereichholz, U., Ettler, R., Holst, Jens Juul, Ørskov, Cathrine, Ritzel, R. & Schmiegel, W. H., Nov 1997, In: American Journal of Physiology (Consolidated). 273, 5 Pt 1, p. E981-8Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Amidated and non-amidated glucagon-like peptide-1 (GLP-1): non-pancreatic effects (cephalic phase acid secretion) and stability in plasma in humans
Wettergren, A., Pridal, L., Wöjdemann, M. & Holst, Jens Juul, 1998, In: Regul. Pept.. 77, p. 83-88Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.
Holst, Jens Juul, Gromada, K. & Rorsman, P., 1998, In: Pflugers Arch.. 435, p. 583-594Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in serum leptin do not correlate to total fat mass in patients with thyrotoxicosis
Zimmermann-Belsing, T., Dreyer, M., Holst, Jens Juul & Feldt-Rasmussen, U., 1998, In: J. Endocrinol.. 49, p. 589-595Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.
Deacon, Carolyn F., Hughes, T. E. & Holst, Jens Juul, 1998, In: Diabetes. 47, p. 764-769Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity
Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In: Diabetologia. 41, p. 271-278Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in CHL cells
Almind, K., Ambye, L., Urhammer, S. A., Hansen, T., Echwald, S. M., Holst, Jens Juul, Gromada, J. L., Thorens, B. & Pedersen, O., 1998, In: Diabetologia. 41, p. 1194-1198Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distal small bowel hormones: Correlation with fasting antroduodenal motility and gastric emptying
Naslund, E., Gryback, P., Backman, L., Jacobsson, H., Holst, Jens Juul, Theodorsson, E. & Hellstrom, P. M., 1998, In: Dig. Dis. Sci.. 43, p. 945-952Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exaggerated secretion of glucagon-like peptide-1 (GLP-1) could cause reactive hypoglycaemia
Toft-Nielsen, M., Madsbad, Sten & Holst, Jens Juul, 1998, In: Diabetologia. 41, 10, p. 1180-1186 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling
Gromada, J., Bokvist, K., Ding, W. G., Holst, Jens Juul, Nielsen, Jens Høiriis & Rorsman, P., 1998, In: Diabetes. 47, 1, p. 57-65 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 increases mass but not frequency or orderliness of pulsatile insulin secretion
Porksen, N., Grøfte, T., Nyholm, B., Holst, Jens Juul, Pincus, S. M., Veldhuis, J. D., Schmitz, O. & Butler, P. C., 1998, In: Diabetes. 47, p. 45-49Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
Flint, A., Raben, Anne, Astrup, A. & Holst, Jens Juul, 1998, In: Journal of Clinical Investigation. 101, 3, p. 515-520 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 - a new hormone and a new drug
Holst, Jens Juul, 1998, In: Ugeskrift for læger. 160, p. 2371-2377Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow
Wettergren, A., Wojdemann, M. & Holst, Jens Juul, 1998, In: Am. J. Physiol.. 275, p. G984-G992Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 retards gastric emptying and small bowel transit in the rat: Effect mediated through central or enteric nervous mechanisms
Tolessa, T., Gutniak, M. K., Holst, Jens Juul, Efendic, S. & Hellstrom, P. M., 1998, In: Dig. Dis. Sci.. 43, p. 2284-2290Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 inhibits centrally induced antral motility in pigs
Wojdemann, M., Wettergren, A., Hartmann, B. & Holst, Jens Juul, 1998, In: Scandinavian Journal of Gastroenterology. 33, p. 828-832Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Importance of small bowel peptides for the improved glucose metabolism 20 years after jejunoileal bypass for obesity
Naslund, E., Backman, L., Holst, Jens Juul, Theodorsson, E. & Hellstrom, P. M., 1998, In: Obes. Surg.. 8, p. 253-260Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure
Nauck, M. A., Sauerwald, A., Ritzel, R., Holst, Jens Juul & Schmiegel, W., 1998, In: Diabetes Care. 21, p. 1925-1931Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of human gastric lipase secretion by glucagon-like peptide-1
Wojdemann, M., Wettergren, A., Sternby, B., Holst, Jens Juul, Larsen, S., Rehfeld, J. F. & Olsen, O., 1998, In: Dig. Dis. Sci.. 43, p. 799-805Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes
Holst, Jens Juul & Deacon, Carolyn F., 1998, In: Diabetes. 47, p. 1663-1670Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibitory effect of glucagon-like peptide-1 on small bowel motility. Fasting but not fed motility inhibited via nitric oxide independently of insulin and somatostatin
Tolessa, T., Gutniak, M. K., Holst, Jens Juul, Efendic, S. & Hellstrom, P. M., 1998, In: J. Clin. Invest.. 102, p. 764-774Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normalization of sting glycemia by intravenous GLP-1 (7-36amide) or (7-37) in Type 2 diabetic patients
Nauck, M. A., Weber, I., Bach, I., Richter, S. H., Ørskov, C., Holst, Jens Juul & Schmiegel, W., 1998, In: Diabetic Medicine. 15, p. 937-945Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutrients of animal origin and function of gut hormones
Holst, Jens Juul, 1998, Food and Health: Role of Animal Products. Paris: Elsevier, p. 13-22Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Obesity - did anything happen since leptin?
Holst, Jens Juul, 1998, In: Ugeskrift for læger. 160, p. 1182-1184Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the treatment of diabetes mellitus with glucagon-like peptide-1.
Holst, Jens Juul, Deacon, Carolyn F., Toft-Nielsen, M. & Bjerre-Knudsen, L., 1998, In: Annals of the New York Academy of Sciences. 865, p. 336-343Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overnight GLP-1 normalizes fasting but not daytime plasma glucose levels in NIDDM patients
Willms, B., Idowu, K., Holst, Jens Juul, Creutzfeldt, W. & Nauck, M. A., 1998, In: Exp. Clin. Endocrinol. Diabetes. 106, p. 103-107Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to alpha-glucosidase inhibition (acarbose) in Type 2 diabetic patients
Seifarth, C., Bergmann, J., Holst, Jens Juul, Ritzel, R., Schmiegel, W. & Nauck, M. A., 1998, In: Diabet. Med.. 15, p. 485-491Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulatory Peptides of the Gut
Holst, Jens Juul, 1998, Small Bowel Disorders. Kluwer Academic PublishersResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
The ethanol augmentation of glucose-induced insulin secretion is abolished by calcium antagonism with nifedipine: No evidence for a role of glucagon-like peptide-1 (GLP-1)
Svartberg, J., Holst, Jens Juul, Gutniak, M. K. & Adner, N., 1998, In: Pancreas. 16, p. 66-71Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The inhibitory effect of glucagon-like peptide-1 (7-36) amide on antral motility is antagonized by its N-terminally truncated primary metabolite GLP-1 (9-36) amide.
Wettergren, A., Wojdemann, M. & Holst, Jens Juul, 1998, In: Peptides. 19, p. 877-882Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus
Jensen, P. B., Blume, N., Mikkelsen, J. D., Larsen, P. J., Jensen, H. I., Holst, Jens Juul & Madsen, O. D., 1998, In: J. Clin. Invest.. 101, p. 503-510Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 2 diabetes with glucagonlike peptide 1
Holst, Jens Juul, 1998, In: Current Opinion in Endocrin. and Diabetes. 5, p. 108-115Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation and molecular characterization of porcine calcitonin gene-related peptide (CGRP) and its endocrine effects in the porcine pancreas
Rasmussen, T. N., Bersani, M., Schmidt, P., Thim, L., Kofod, H., Jørgensen, P. N., Poulsen, Steen Seier & Holst, Jens Juul, Mar 1998, In: Pancreas. 16, 2, p. 195-204 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in type 2 diabetic patients
Nauck, M. A., Weber, I., Bach, I., Richter, S., Ørskov, Cathrine, Holst, Jens Juul & Schmiegel, W., Nov 1998, In: Diabetic Medicine Online. 15, 11, p. 937-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Advances in non-peptide glucagon receptor antagonist
Madsen, P., Knudsen, L. B., Brand, C. L. & Holst, Jens Juul, 1999, In: Curr. Pharm Design. 5, p. 683-691Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Continuous subcutaneous infusion of Glucagon-like Peptide-1 (GLP-1) lowers plasma glucose and reduces appetite in type II diabetic patients
Toft-Nielsen, M. B., Madsbad, S. & Holst, Jens Juul, 1999, In: Diabetes Care. 22, p. 1137-1143Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetic Intestinal Growth Adaptation and glucagon-like peptide 2 (GLP-2) in the rat. Effect of dietary fibres
Thulesen, J., Hartmann, B., Nielsen, C., Holst, Jens Juul & Poulsen, S. S., 1999, In: Gut. 45, p. 672-678Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of saturated and monounsaturated fat on postprandial lipaemia and GIP/GLP-1 response in healthy subjects
Thomsen, C., Rasmussen, O., Lousen, T., Hermansen, K. & Holst, Jens Juul, 1999, In: Am. J. Clin. Nutri.. 69, p. 1135-1143Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Energy intake and appetite is suppressed by glucagon-like peptide-1 (GLP-1) in obese men
Näslund, E., Barkeling, B., King, N., Gutniak, M. K., Blundell, J. E., Holst, Jens Juul, Rössner, S. & Hellström, P. M., 1999, In: International Journal of Obesity. 23, p. 304-311Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fast acting nervous regulation of immunoglobulin A secretion from isolated perfused porcine ileum
Schmidt, P. T., Eriksen, L., Loftager, M., Rasmussen, T. N. & Holst, Jens Juul, 1999, In: Gut. 45, p. 679-685Research output: Contribution to journal › Journal article › Research
- Published
Glucagon-like peptide-1 (GLP-1): An intestinal hormone, signalling nutritional abundance, with an unusual therapeutic potential
Holst, Jens Juul, 1999, In: Trends in Endocrinology and Metabolism. 10, p. 229-235Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 slows solid gastric emptying and inhibits insulin, glucagon and peptide YY release in humans
Näslund, E., Bogefors, J., Skogar, S., Grybäck, P., Jacobsen, H. L., Holst, Jens Juul & Helström, P. M., 1999, In: Am. J. Physiol.. 277, p. 910-916Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 suppresses energy expenditure in obese humans
Flint, A., Raben, A., Holst, Jens Juul & Astrup, A., 1999, International journal of obesity. Després, J-P. & Macdonald, I. (eds.). 23 ed. European Association for the Study of Obesity, p. S35 1 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Glucagon-like peptide-1(7-36)amide is transformed to glucagon-like peptide-1 (9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the intestinal L-cells
Hansen, L., Deacon, Carolyn F., Ørskov, C. & Holst, Jens Juul, 1999, In: Endokrinologiya. 140, p. 5356-5363Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1, a gastrointestinal hormone with a pharmaceutical potential
Holst, Jens Juul, 1999, In: Current Medicinal Chemistry. 6, p. 1005-1017Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1: A basis for new approaches to the management of Diabetes
Deacon, Carolyn F., Holst, Jens Juul & Carr, R. D., 1999, In: Drugs of Today. 35, p. 159-170Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hour profiles of insulin, subtrates and gut incretin hormones: Early defects in glucose tolerant offspring of type II (non-insulin dependent) diabetic paitents
Nyholm, B., Walker, M. J. C., Gravholdt, C. H., Alberti, K. G. M. M., Holst, Jens Juul & Schmitz, O., 1999, In: Diabetologia. 42, p. 1314-1323Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human gastric lipase secretion is inhibited by intraduodenal perfusion of dietary fat.
Wøjdemann, M., Riber, C., Bisgaard, T., Sternby, B., Larsen, S., Rehfeld, J. F., Holst, Jens Juul & Olesen, O., 1999, In: Regulatory Peptides. 80, p. 101-106Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired meal-stimulated glucagon-like peptide-2 responses in short bowel patients with intestinal failure
Jeppesen, P. B., Hansen, B. S., Hartmann, B., Holst, Jens Juul & Mortensen, P. B., 1999, In: Gut. 45, p. 559-563Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Importance of colonic fermentation in short bowel patients. Small intestinal malabsorption of easily digestible carbohydrate
Olesen, M., Gudmand-Høyer, E., Holst, Jens Juul & Jørgensen, S., 1999, In: Dig. Dis. Sci.. 44, p. 1914-1923Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased Circulating leptin in cirrhosis: relation to release and disposal
Henriksen, J. H., Holst, Jens Juul, Møller, S., Brinch, K. & Bendtsen, Flemming, 1999, In: Hepatology. 29, p. 1818-1824Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased intensity of physical activity stimulates subsequent fat intake
Klausen, B., Toubro, S., Ranneries, C., Rehfeld, J. F., Holst, Jens Juul, Christensen, N. J. & Astrup, A., 1999, In: International Journal of Obesity. 23, p. 1282-1287Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of dipeptidyl peptidase IV with NVP DPP728 increases plasma GLP-1 (7-36amide) concentrations and improves oral glucose tolerance in obese Zucker rats
Balkan, B., Kwasnik, L., Miserendino, R., Holst, Jens Juul & Lie, X., 1999, In: Diabetologia. 42, p. 1324-1331Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of shamfeeding stimulated human gastric acid secretion by glucagon-like peptide-2
Wøjdemann, M., Wettergren, A., Hartmann, B., Hilsted, L. M. & Holst, Jens Juul, 1999, In: J. Clin. Endocrinol. Metab.. 84, p. 2513-2517Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Octreotide suppresses the incretin GLP-1 in patients with acromegally, clinically nonfunctioning pituitary tumours and in healthy subjects
Plöckinger, U., Holst, Jens Juul, Messerschmidt, D., Hopfenmüller, W. & Quabbe, H. J., 1999, In: European Journal of Endocrinology. 140, p. 538-544Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proglucagon cleavage profile in canine L-cells expressing endogenous PC-1/3 and PC-2
Damholt, A. B., Buchan, A. M. J., Holst, Jens Juul & Kofod, H., 1999, In: Endokrinologiya. 140, p. 4800-4808Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selectivity of prandial glucose regulators: nateglinide, but not repaglinide, accelerates exocytosis in rat pancreatic A-cells
Bokvist, K., Høy, M., Buschard, K., Holst, Jens Juul, Thomsen, M. K. & Gromada, J. L., 1999, In: Eur. J. Pharmacol.. 386, p. 105-111Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tachykinins stimulate acid and pepsinogen secretion in the isolated perfused porcine stomach
Schmidt, P. T., Rasmussen, T. N. & Holst, Jens Juul, 1999, In: Acta Physiologica (Print Edition). 166, p. 335-340Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tachykinins stimulate the release of peptide hormones (glucagon-like peptide-1), and paracrine - (somatostatin) and neurotransmitters (vasoactive intestinal polypeptide) from porcine ileum through NK-1 receptors
Schmidt, P. T., Rickelt, L. F. & Holst, Jens Juul, 1999, In: Digestive Diseases and Sciences. 44, p. 1273-1281Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The arcuate nucleus is pivotal in mediating the anorectic effects of centrally administered leptin
Tang-Christensen, M., Holst, Jens Juul, Hartmann, B. & Vrang, N., 1999, In: NeuroReport. 10, p. 1183-1187Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The hypothalamic satiety peptide CART is expressed in anorectic and non-anorectic pancreatic islet tumors and in the normal islet of Langerhans
Jensen, P. B., Kristensen, P., Clausen, J. T., Judge, M. E., Hastrup, S., Thim, L., Wulff, B. S., Foged, C., Jensen, J., Holst, Jens Juul & Madsen, O. D., 1999, In: FEBS Letters. 447, p. 139-143Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of Type 2 diabetes mellitus based on glucagon-like peptide-1
Holst, Jens Juul, 1999, In: Exp. Opin. Invest. Drugs. 8, p. 1409-1415Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1: a basis for new approaches to the management of diabetes
Deacon, Carolyn F., Holst, Jens Juul & Carr, R. D., Mar 1999, In: Drugs of Today. 35, 3, p. 159-70 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of Type 2 diabetes mellitus based on glucagon-like peptide-1
Holst, Jens Juul, Sep 1999, In: Expert Opinion on Investigational Drugs. 8, 9, p. 1409-15 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proglucagon processing profile in canine L cells expressing endogenous prohormone convertase 1/3 and prohormone convertase 2
Damholt, A. B., Buchan, A. M., Holst, Jens Juul & Kofod, H., Oct 1999, In: Endocrinology. 140, 10, p. 4800-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetic intestinal growth adaptation and glucagon-like peptide 2 in the rat: effects of dietary fibre
Thulesen, J., Hartmann, Bolette, Nielsen, C., Holst, Jens Juul & Poulsen, Steen Seier, Nov 1999, In: Gut. 45, 5, p. 672-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine
Hansen, L., Deacon, Carolyn F., Ørskov, Cathrine & Holst, Jens Juul, Nov 1999, In: Molecular Endocrinology. 140, 11, p. 5356-63 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
1,5-Anhydro fructose increase glucose tolerance by increasing GLP-1 and insulin in mice
Ahrén, B., Holst, Jens Juul, Marcussen, J. & Yu, S., 2000, In: Eur. J. Pharmacol.. 397, p. 219-225Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetogenic action of cholecystokinin in type 2 diabetes
Ahrén, B., Holst, Jens Juul & Efendic, S., 2000, In: J. Clin. Endocrinol. Metab.. 85, p. 1043-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating levels of incretin hormones an amylin in the fasting state and after oral glucose in growth hormone (GH-)deficient patients before and after GH replacement. A placebo controlled study
Jørgensen, J. O. L., Rosenfalck, A. M., Fisker, S., Nyholm, B., Fineman, M. S., Schmitz, O., Madsbad, S., Holst, Jens Juul & Christiansen, J. S., 2000, In: European Journal of Endocrinology. 143, p. 593-599Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide
Deacon, Carolyn F., Nauck, M. A., Meier, J., Hücking, K. & Holst, Jens Juul, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, p. 3575-3581Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice
Hartmann, Bolette, Thulesen, J., Kissow, Hannelouise, Thulesen, S., Ørskov, Cathrine, Ropke, C., Poulsen, Steen Seier & Holst, Jens Juul, 2000, In: Endocrinology. 141, 11, p. 4013-20 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of glucagon-like peptide 1 (7-356) amide in insulin treated patients with diabetes mellitus secondary to chronic pancreatitis
Hedetoft, C., Larsen, S., Sheikh, S. & Holst, Jens Juul, 2000, In: Pancreas. 20, p. 25-31Research output: Contribution to journal › Journal article › Research
- Published
Effect of glucagon-like peptide-1-(7,36)-amide on glucose effectiveness and insulin action in people with type 2 diabetes mellitus
Vella, A., Shah, P., Basu, R., Basu, A., Holst, Jens Juul & Rizza, R. A., 2000, In: Diabetes. 49, p. 611-617Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of oral glucose on systemic glucose metabolism during hyperinsulinaemic hypoglycemia in normal man
Poulsen, P. L., Grøfte, T., Holck, P., Møller, J., Schmitz, O., Ørskov, L., Holst, Jens Juul & Møller, N., 2000, In: Metabolism. 49, p. 1598-1603Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated circulating leptin in arterial hypertension: relationship to arteriovenous overflow and extraction of leptin
Henriksen, J. H., Holst, Jens Juul, Møller, S., Jensen, G. & Bendtsen, Flemming, 2000, In: Clin.Sci.. 99, p. 527-534Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated fasting glucagon-like peptide 1 and 2 secretion in ileum-resected short bowel patients with a preserved colon
Jeppesen, P. B., Hartmann, B., Hansen, B. S., Poulsen, Steen Seier, Thulesen, J., Holst, Jens Juul & Mortensen, P. B., 2000, In: Gut. 47, p. 370-376Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of ß-cell secretory capacity using glucagon-like peptide-1
Visbøll, T., Toft-Nielsen, M., Krarup, T., Madsbad, S., Dinesen, B. & Holst, Jens Juul, 2000, In: Diabetes Care. 23, p. 807-812Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 stimulates intestinal growth by suppressing proteolysis and apoptosis in TNP-fed premature pigs
Burrin, D. G., Stoll, B., Jiang, R., Petersen, Y., Elnif, J., Buddington, R. K., Schmidt, M., Holst, Jens Juul, Hartmann, B. & Sangild, P. T., 2000, In: Am. J. Physiol.. 279, p. G1249-G1256Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose mediated glucose disposal in insulin resistant normoglycemic relatives of type 2 diabetic patients
Henriksen, J. E., Levin, K., Thye-Rønn, P., Alford, F., Hother-Nielsen, O., Holst, Jens Juul & Beck-Nielsen, H., 2000, In: Diabetes. 49, p. 1209-1218Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gut hormones as pharmaceuticals. From enteroglucagon to GLP-1 and GLP-2
Holst, Jens Juul, 2000, In: Review Regul Pept. 93, p. 45-51Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved glucagon tolerance and insulin secretion by inhibition of dipeptidyl peptidase IV in mice
Ahrén, B., Holst, Jens Juul, Mårtensson, H. & Balkan, B., 2000, In: Eur. J. Pharmacol.. 404, p. 239-245Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo and in vitro degradation of glucagon-like peptide-2 in humans
Hartmann, B., Harr, M. B., Jeppesen, P. B., Wojdemann, M., Deacon, Carolyn F., Mortensen, P. B. & Holst, Jens Juul, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, p. 2884-2888Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of acarbose on postprandial insulin requirements in patients with type 1 diabetes
Juntti-Berggren, L., Pigon, J., Hellström, P. M., Holst, Jens Juul & Efendic, S., 2000, In: Diab Nutr Metab. 13, p. 7-12Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Minimal enteral nutrient requirements for intestinal growth in neonatal piglets: how much is enough?
Burrin, D. G., Stoll, B., Jiang, R., Chang, X., Hartmann, B., Holst, Jens Juul, Greeley, G. H. & Reeds, P. J., 2000, In: Am. J. Clin. Nutr.. 71, p. 1603-1610Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neurogenic nitric oxide and exocrine secretion in the gastrointestinal tract
Ørskov, Cathrine & Holst, Jens Juul, 2000, Nitric Oxide and the Peripheral Nervous System. London, UK: Portland Press Ltd., p. 131Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
PACAP 1-38 as neurotransmitter in porcine adrenal glands
Tornøe, K., Hannibal, J., Rickelt, L. F., Bolding Jensen, M., Børglum, J. T., Fahrenkrug, J. & Holst, Jens Juul, 2000, In: American Journal of Physiology: Endocrinology and Metabolism. 279, p. E1412-E1425Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PACAP contributes to insulin secretion after gastric glucose gavage in mice
Filipsson, K., Holst, Jens Juul & Ahrén, B., 2000, In: Am. J. Physiol.. 279, p. R424-432Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2
Thulesen, J., Hartmann, B., Ørskov, Cathrine, Jeppesen, P. B., Holst, Jens Juul & Poulsen, Steen Seier, 2000, In: Peptides. 10, p. 1511-1517Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulatory peptides of the gastrointestinal tract
Holst, Jens Juul, 2000, Small Bowel Disorders. London: Small Bowel Disorders, p. 96-115Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Short-term treatment with GLP-1 increases pulsatile secretion in type 2 diabetes with no effect on orderliness.
Juhl, C. B., Schmitz, O., Holst, Jens Juul, Vedhuis, J. & Pørksen, N., 2000, In: Diabetologia. 43, p. 583-588Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Somastostatin restrains the secretion of glucagon-like peptide-1 and 2 (GLP-1 and GLP-2) from isolated perfused porcine ileum
Hansen, L., Hartmann, B., Bisgaard, T., Mineo, H., Jørgensen, P. N. & Holst, Jens Juul, 2000, In: Am. J. Physiol.. 278, p. E1010-E1018Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tachykinins in the porcine pancreas: potent exocrine and endocrine effects via NK-1 receptors
Schmidt, P. T., Tornøe, K., Poulsen, Steen Seier, Nygaard, T. & Holst, Jens Juul, 2000, In: Pancreas. 20, p. 241-247Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tachykinins in the regulation of gastric motility and secretion
Schmidt, P. T. & Holst, Jens Juul, 2000, In: Review Cellular and Molecular Life Sciences. 57, p. 579-588Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of glucagon-like peptide-1 on energy expenditure and substrate metabolism in humans
Flint, A., Raben, A., Rehfeld, J. F., Holst, Jens Juul & Astrup, A., 2000, In: International Journal of Obesity. 24, p. 288-298Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tachykinins in the porcine pancreas: potent exocrine and endocrine effects via NK-1 receptors
Schmidt, P. T., Tornøe, K., Poulsen, Steen Seier, Rasmussen, T. N. & Holst, Jens Juul, Apr 2000, In: Pancreas. 20, 3, p. 241-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells
Schmidt, P. T., Hartmann, Bolette, Bregenholt, S., Holst, Jens Juul & Claesson, Mogens Helweg, 1 May 2000, In: Scandinavian Journal of Gastroenterology. 35, 5, p. 522-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon
Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Hansen, B. S., Holst, Jens Juul, Poulsen, Steen Seier & Mortensen, P. B., Sep 2000, In: Gut. 47, 3, p. 370-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2
Thulesen, J., Hartmann, Bolette, Ørskov, Cathrine, Jeppesen, Palle Bekker, Holst, Jens Juul & Poulsen, Steen Seier, Oct 2000, In: Peptides. 21, 10, p. 1511-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2001
- Published
Additive glucose-lowering effects of glucagon-like peptide- 1 and metformin type 2 diabetes
Zander, M., Taskiran, M., Toft-Nielsen, M. B. & Holst, Jens Juul, 2001, In: Diabetes Care. 24, p. 720-725Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetogenic action of glucagon-like peptide- 1 related to administration relative to meal intake in subjects with type 2 diabetes
Gutniak, M. K., Svartberg, J., Hellstrom, P. M. & Holst, Jens Juul, 2001, In: J Intern Med. 250, p. 81-87Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assesment of hepatic insulin action in obese type 2 diabetic patients
Staehr, P., Hother-Nielsen, O., Levin, K. & Holst, Jens Juul, 2001, In: Diabetes. 50, p. 1363-1370Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Attenuated processing of proglucagon and glucagon-like peptide- 1 in carboxypeptidase E-deficient mice
Friis-Hansen, L., Lacourse, K. A., Samuelson, L. C. & Holst, Jens Juul, 2001, In: J. Endocrinol.. 169, p. 595-602Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determinants of the effectiveness of glucagon-like peptide- 1 in type 2 diabetes
Toft-Nielsen, M. B., Madsbad, S. & Holst, Jens Juul, 2001, In: J Clin Endocr Metab. 86, p. 3853-3860Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determinants of the impaired secretion of glucagon-like peptide-1 in type 2 diabetic patients
Toft-Nielsen, M. B., Damholt, M. B., Madsbad, Sten, Hilsted, L. M., Hughes, T. E., Michelsen, B. K. & Holst, Jens Juul, 2001, In: Journal of Clinical Endocrinology and Metabolism. 86, 8, p. 3717-3723 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs
Deacon, Carolyn F., Danielsen, P., Klarskov, L., Holst, Jens Juul & Olesen, M., 2001, In: Diabetes. 50, p. 1588-1597Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diurnal metabolic profiles after 14 d of an ad libitum high-starch, high-sucrose, or high-fat diet in normal-weight never-obese and postobese women
Raben, A., Holst, Jens Juul, Madsen, J. & Astrup, A., 2001, In: American Journal of Clinical Nutrition. 73, p. 177-89 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of glucagon-like peptide- 1 (7-36)-amide on initial splanchnic glucose uptake and insulin action in humans with type 1 diabetes
Vella, A., Shah, P., Basu, R. & Holst, Jens Juul, 2001, In: Diabetes. 50, p. 565-572Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated ciculating leptin levels in arterial hypertension: relationship to arteriovenous overflow and extraction of leptin
Henriksen, J. H., Holst, Jens Juul & Moller, S., 2001, In: Clin.Sci.. 99, p. 527-534Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 derivatives as novel compounds for the treatment of type 2 diabetes: selection of NN2211 for clinical development
Knudsen, L. B., Agerso, H., Bjenning, C. & Holst, Jens Juul, 2001, In: Drug Future. 26, p. 677-685Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 inhibits gastric emptying of water but does not influence plasma vasopressin, sodium, or osmolality
Naslund, E., Bogefors, J., Gryback, P. & Holst, Jens Juul, 2001, In: Scand J Gastroentero. 36, p. 156-162Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 stimulates intestinal growth in premature TPN-fed pigs by suppressing proteolysis and apoptosis
Burrin, D. G., Stoll, B., Jiang, R. & Holst, Jens Juul, 2001, In: Am J Physiol-Gastr L. 279, p. G1249-G1256Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric myoelectrical activity and gut hormone secretion in myotonic dystrophy
Ronnblom, A., Hellstrom, P. M. & Holst, Jens Juul, 2001, In: Eur J Gastroen Hepat. 13, p. 825-831Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 increases secretory burst mass of pulsatile insulin secretion in patients with type 2 diabetes and impaired glucose tolerance
Ritzel, R., Schulte, M., Porksen, N. & Holst, Jens Juul, 2001, In: Diabetes. 50, p. 776-784Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 stimulates intestinal growth by decreasing proteolysis and apoptosis in parenterally fed premature piglets
Burrin, D. G., Stoll, B., Jiang, R., Petersen, Y., Elnif, J., Buddington, R. K., Schmidt, M., Holst, Jens Juul, Hartmann, B. & Sangild, Per Torp, 2001, Ikke angivet. Lindberg, J. E., Ogle & B. (eds.). CABI Publishing, p. 40-42 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Glucagon-like peptide 2 stimulates small-intestine growth and maturation in the pig fetus and neonate
Petersen, Y. M., Burrin, D. G., Schmidt, M., Elnif, J., Hartmann, B., Holst, Jens Juul & Sangild, Per Torp, 2001, Ikke angivet. Lindberg, J. E., Ogle & B. (eds.). CABI Publishing, p. 23-25 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Impaired incretin response after a mixed meal is associated with insulin resistance in nondiabetic men
Rask, E., Olsson, T., Soderberg, S. & Holst, Jens Juul, 2001, In: Diabetes Care. 24, p. 1640-1645Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormones - an update
Holst, Jens Juul & Orskov, C., 2001, In: Scand J Clin Lab Inv. 61 Suppl. 234, p. 75-85Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormones--an update
Holst, Jens Juul & Ørskov, Cathrine, 2001, In: Scandinavian Journal of Clinical & Laboratory Investigation. 234, p. 75-85 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Inhibition of gastric emptying by acarbose is correlated with GLP-1 response and accompanied by CCK release
Enc, F. Y., Imeryuz, N., Akin, L. & Holst, Jens Juul, 2001, In: Am J Physiol-Gastr L. 281, p. G752-G763Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal--jejunal transposition or small bowel resection
Thulesen, J., Hartmann, Bolette, Kissow, Hannelouise, Jeppesen, Palle Bekker, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2001, In: Digestive Diseases and Sciences. 46, 2, p. 379-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal-jejunal transposition or small bowel resection
Thulesen, J., Hartmann, B., Kissow, H., Jeppesen, P. B., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2001, In: Digestive Diseases and Sciences. 46 (2), p. 379-388Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intestinal nutrient absorption in newborn pigs in response to enteral nutrition or treatment with glucagon-like peptide 2
Elnif, J., Buddington, R. K., Petersen, Y. M., Hartmann, B., Holst, Jens Juul, Schmidt, M., Burrin, D. G. & Sangild, Per Torp, 2001, Ikke angivet. Lindberg, J. E., Ogle & B. (eds.). CABI Publishing, p. 37-39 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
PACAP 1-38 as neurotransmitter in the porcine antrum
Tornoe, K., Hannibal, J., Georg, B. & Holst, Jens Juul, 2001, In: Regulatory Peptides. 101, p. 109-121Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perinatal gut growth is not regulated by glucagon-like peptide 2
Petersen, Y. M., Holst, Jens Juul, Hartmann, B. & Sangild, Per Torp, 2001, Journal of the Society for Gynecological Investigation. 8 ed. p. 172A 1 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Postprandial GLP-1, norepinephrine, and reactive hypoglycemia in dumping syndrome
Gebhard, B., Holst, Jens Juul & Biegelmayer, C., 2001, In: Digest Dis Sci. 46, p. 1915-1923Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced insulinotropic effect of gastric inhibitory polypeptide in first-degree relatives of patients with type 2 diabetes
Meier, J. J., Huking, K., Holst, Jens Juul, Deacon, Carolyn F., Schmiegel, W. H. & Nauck, M. A., 2001, In: Diabetes. 50, p. 2497-2504Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reference intervals for glucose, beta-cell polypeptides, and counterregulatory factors during prolonged fasting
Hojlund, K., Wildner-Christensen, M., Eshoj, O. & Holst, Jens Juul, 2001, In: Am J Physiol-Endoc M. 280, p. E50-E58Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reference intervals for plasma glucose, insulin, proinsulin, C-peptide and counterregulatory factors during a 72-hour fast in healthy human subjects
Højlund, K., Eshøj, O., Christensen, M. W., Skjærbæk, C., Frystyk, J., Holst, Jens Juul, Koldkjær, O., Møller J., D. & Beck-Nielsen, H., 2001, In: American Journal of Physiology.. 280, p. E50-E58Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of trophic gut peptides is not different in bolus- and continuously fed piglets
Goudoever, V., Stoll, B., Hartmann, B., Holst, Jens Juul, Reeds, P. J. & Burrin, D. G., 2001, In: J Nutr.. 131, p. 729-732Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cephalic insulin response to meal ingestion in humans is dependent on both cholinergic and noncholinergic mechanisms and is important for postprandial glycemia
Ahrén, B. & Holst, Jens Juul, 2001, In: Diabetes. 50, p. 1030-1038Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of postprandial releases of insulin and incretin hormones in meal-induced satiety - effect of obesity and weight reduction
Verdich, C., Toubro, S., Buemann, B. & Holst, Jens Juul, 2001, In: International Journal of Obesity. 25, p. 1206-1214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-dependent intestinal adaptation and GLP-2 alterations after small bowel resection in rats
Ljungmann, K., Hartmann, B., Kissmeyer-Nielsen, P. & Holst, Jens Juul, 2001, In: Am J Physiol-Gastr L. 281, p. G779-G785Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of short bowel patients with glucagon-like peptide-2 (GLP-2), a newly discovered intestinotrophic, anti-secretory, and transit modulating peptide
Jeppesen, P. B., Hartmann, B., Thulesen, J., Graff, J., Lohmann, J., Hansen, B. S., Tofteng, F., Poulsen, S. S., Madsen, J. L., Holst, Jens Juul & Mortensen, P. B., 2001, In: Today in Medicine. Gastroenterology. 120, p. 806-815Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No reactive hypoglycaemia in type 2 diabetic patients after subcutaneous administration of GLP-1 and intravenous glucose
Vilsbøll, Tina, Krarup, T., Madsbad, Sten & Holst, Jens Juul, 1 Feb 2001, In: Diabetic Medicine. 18, 2, p. 144-149 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon
Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Graff, J., Lohmann, J., Hansen, B. S., Tofteng, F., Poulsen, Steen Seier, Madsen, J. L., Holst, Jens Juul & Mortensen, P. B., Mar 2001, In: Gastroenterology. 120, 4, p. 806-815 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Localisation and neural control of the release of calcitonin gene-related peptide (CGRP) from the isolated perfused porcine ileum
Rasmussen, T. N., Schmidt, P., Poulsen, S. S., Holst, Jens Juul & Poulsen, Steen Seier, 20 Apr 2001, In: Regulatory Peptides. 98, 3, p. 137-143 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of calcitonin gene-related peptide (CGRP) on motility and on the release of substance P, neurokinin A, somatostatin and gastrin in the isolated perfused porcine antrum
Rasmussen, T. N., Schmidt, P., Poulsen, S. S., Holst, Jens Juul & Poulsen, Steen Seier, 1 Aug 2001, In: Neurogastroenterology and Motility. 13, 4, p. 353-359 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
Abnormal release of incretins and cortisol after oral glucose in insulin resistant myotonic dystrophy
Johansson, Å., Olsson, T., Cederquist, K., Forsberg, H., Holst, Jens Juul, Seckl, J. R. & Ahrén, B., 2002, In: European Journal of Endocrinology. 146, p. 397-405Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Case report: Somatostatin producing teratoma, causing rapidly alternating extreme hyperglycemia and hypoglycemia, and ovarian somatostatinoma
Gregersen, G., Holst, Jens Juul, Trankjaer, A., Stadil, F. & Mogensen, A. M., 2002, In: Metabolism. 51, 9, p. 1180-1183 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase IV inhibition as an approach to the treatment and prevention of type 2 diabetes: a historical perspective.
Deacon, Carolyn F. & Holst, Jens Juul, 2002, In: Biochemical and Biophysical Research Communications. 294, 1, p. 1-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight.
Jensen, C. B., Storgaard, H., Dela, Flemming, Holst, Jens Juul, Madsbad, Sten & Vaag, Allan, 2002, In: Diabetes. 51, 4, p. 1271-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study.
Olsen, Ane Mette Zander, Madsbad, Sten, Madsen, J. L. & Holst, Jens Juul, 2002, In: Lancet. 359, 9309, p. 824-30 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of glucagon-like peptide-1 (GLP-1) on counterregulatory hormone responses, cognitive functions and insulin secretion during hyperinsulinaemic, stepped hypoglycaemic clamp experiments in healthy volunteers
Nauck, M. A., Heimesaat, M. M., Behle, K., Holst, Jens Juul, Nauck, M. S., Hüfner, M. & Schmiegel, W. H., 2002, In: J. Clin. Endocrinol. Metab.. 87, p. 1239-1246Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Et nyopdaget fotopigment i retina, melanopsin, styrer hjernens biologiske ur.
Hannibal, J., Fahrenkrug, J. & Holst, Jens Juul, 2002, In: Ugeskrift for læger. 164, 19, p. 2523Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fedtvaevet og insulin-resistens: resistin og adiponectin.
Holst, Jens Juul & Binderup, M., 2002, In: Ugeskrift for læger. 164, 16, p. 2173-6 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 and GLP-2 act in concert to inhibit fasted, but not fed, small bowel motility in the rat.
Bozkurt, A., Näslund, E., Holst, Jens Juul & Hellström, P. M., 2002, In: Regulatory Peptides. 107, 1-3, p. 129-35 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1-(9-36) amide reduces blood glucose in anesthetized pigs by a mechanism that does not involve insulin secretion.
Deacon, Carolyn F., Plamboeck, A., Møller, Søren & Holst, Jens Juul, 2002, In: American Journal of Physiology: Endocrinology and Metabolism. 282, 4, p. E873-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric inhibitory polypeptide analogues: do they have a therapeutic role in diabetes mellitus similar to that of glucagon-like Peptide-1?
Holst, Jens Juul, 2002, In: BioDrugs. 16, 3, p. 175-81 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gliclazide directly inhibits arginine-induced glucagon release.
Cejvan, K., Coy, D. H., Holst, Jens Juul, Cerasi, E. & Efendic, S., 2002, In: Diabetes. 51 Suppl 3, p. S381-4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunoneutralization of endogenous glucagon-like peptide-2 reduces adaptive intestinal growth in diabetic rats.
Hartmann, B., Thulesen, J., Hare, K. J., Kissow, Hannelouise, Orskov, C., Poulsen, Steen Seier & Holst, Jens Juul, 2002, In: Regulatory Peptides. 105, 3, p. 173-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of gastric inhibitory polypeptide signaling prevents obesity.
Miyawaki, K., Yamada, Y., Ban, N., Ihara, Y., Tsukiyama, K., Zhou, H., Fujimoto, S., Oku, A., Tsuda, K., Toyokuni, S., Hiai, H., Mizunoya, W., Fushiki, T., Holst, J. J., Makino, M., Tashita, A., Kobara, Y., Tsubamoto, Y., Jinnouchi, T., Jomori, T. & 1 others, , 2002, In: Nature Medicine. 8, 7, p. 738-42 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice
Reimer, M. K., Holst, Jens Juul & Ahrén, B., 2002, In: European Journal of Endocrinology. 146, p. 717-727Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial glucose, insulin and incretin responses to grain products in healthy subjects
Juntunen, K. S., Lioukkonen, H. K., Poutanen, S. K., Niskanen, K. L., Holst, Jens Juul & Mykkänen, M. H., 2002, In: Am. J. Clin. Nutr.. 75, p. 254-262Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preservation of active Effects of topical ropivacaine om eicosanoids and neurotransmitters in the rectum of patients with distal ulcerative colitis
Hillingsøe, J. G., Kjeldsen, J., Schmidt, P. T., Rasmussen, T. N., Arlander, E., Fischer-Hansen, B., Holst, Jens Juul, Lauritsen, K., Bukhave, K. & Rask-Madsen, J., 2002, In: Scandinavian Journal of Gastroenterology. 37, p. 325-329Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term administration of Glucagon-like peptide-2. Effects on bone mass density and markers of bone remodelling in short bowel patients with no colon
Haderslev, K. V., Jeppesen, P. B., Hartmann, B., Thulesen, J., Sørensen, H. A., Graff, J., Hansen, B. S., Tofteng, F., Poulsen, Steen Seier, Madsen, J. L., Holst, Jens Juul, Staun, M. & Mortensen, P. B., 2002, In: Scandinavian Journal of Gastroenterology. vol. 37, p. 392-398Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist.
Thulesen, J., Knudsen, L. B., Hartmann, B., Hastrup, S., Kissow, Hannelouise, Jeppesen, P. B., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2002, In: Regulatory Peptides. 103, 1, p. 9-15 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Therapy of type 2 diabetes mellitus based on the actions of glucagon-like peptide-1.
Holst, Jens Juul, 2002, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 18, 6, p. 430-41 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preservation of active incretin hormones by inhibition of dipeptidyl peptidase IV suppresses meal-induced incretin secretion in dogs
Deacon, Carolyn F., Wamberg, S., Bie, P., Hughes, T. E. & Holst, Jens Juul, Feb 2002, In: Journal of Endocrinology. 172, 2, p. 355-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abnormal release of incretins and cortisol after oral glucose in subjects with insulin-resistant myotonic dystrophy
Johansson, A., Olsson, T., Cederquist, K., Forsberg, H., Holst, Jens Juul, Seckl, J. R. & Ahren, B., Mar 2002, In: European Journal of Endocrinology. Supplement. 146, 3, p. 397-405 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers
Nauck, M. A., Heimesaat, M. M., Behle, K., Holst, Jens Juul, Nauck, M. S., Ritzel, R., Hüfner, M. & Schmiegel, W. H., Mar 2002, In: The Journal of clinical endocrinology and metabolism. 87, 3, p. 1239-46 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of topical ropivacaine on eicosanoids and neurotransmitters in the rectum of patients with distal ulcerative colitis
Hillingsø, Jens Georg, Kjeldsen, J., Schmidt, P. T., Rasmussen, T. N., Fisher-Hansen, B., Holst, Jens Juul, Lauristen, K., Bukhave, K. & Rask-Madsen, J., Mar 2002, In: Scandinavian Journal of Gastroenterology. 37, 3, p. 325-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon
Haderslev, Kent Valentin, Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Sorensen, H. A., Graff, J., Tofteng, F., Poulsen, S. S., Madsen, J. L., Holst, Jens Juul, Staun, Michael, Mortensen, P. B. & Poulsen, Steen Seier, 1 Apr 2002, In: Scandinavian Journal of Gastroenterology. 37, 4, p. 392-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice
Reimer, M. K., Holst, Jens Juul & Ahrén, B., May 2002, In: European Journal of Endocrinology. Supplement. 146, 5, p. 717-27 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating levels of ghrelin and GLP-1 are inversely related during glucose ingestion
Djurhuus, C. B., Hansen, T. K., Gravholt, C., Ørskov, L., Hosoda, H., Kangawa, K., Jørgensen, J. O. L., Holst, Jens Juul & Schmitz, O., Jul 2002, In: Hormone and Metabolic Research. Supplement. 34, 7, p. 411-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Feast or famine - are GLP-1 and ghrelin secretion intertwined?
Djurhuus, C. B., Hansen, T. K., Holst, Jens Juul & Schmitz, O., Jul 2002, In: Hormone and Metabolic Research. Supplement. 34, 7, p. 353-4 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects
Zhu, X., Zhou, A., Dey, A., Norrbom, C., Carroll, R., Zhang, C., Laurent, V., Lindberg, I., Ugleholdt, Randi Kjærsgaard, Holst, Jens Juul & Steiner, D. F., 6 Aug 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 16, p. 10293-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-diabetogenic effect of the human amylin analogue, pramlintide, in Type 1 diabetes is not mediated by GLP-1
Ahrén, B., Adner, N., Svartberg, J., Petrella, E., Holst, Jens Juul & Gutniak, M. K., Sep 2002, In: Diabetic Medicine. 19, 9, p. 790-2 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Repaglinide at a cellular level
Krogsgaard Thomsen, M., Bokvist, K., Høy, M., Buschard, K., Holst, Jens Juul, Lindström, P. & Gromada, J., Dec 2002, In: Diabetes, nutrition & metabolism. 15, 6 Suppl, p. 15-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of duodenal peptides on glucagon-like peptide-1 secretion from the ileum. A duodeno--ileal loop?
Hansen, L. & Holst, Jens Juul, 31 Dec 2002, In: Regulatory Peptides. 110, 1, p. 39-45 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Absence of a memory effect for the insulinotropic action of glucagon-like peptide 1(GLP-1) in healthy volunteers
Meier, S., Hücking, K., Ritzelt, R., Holst, Jens Juul, Schmiegel, W. H. & Nauck, M. A., 2003, In: Horm Metab Res. 35, p. 551-556Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of GLP-1 effects on beta cell function after meal ingestion in humans
Ahren, B., Holst, Jens Juul & Mari, A., 2003, In: Diabetes Care. 26, p. 2860-2864Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating leptin and thyroid dysfunction.
Zimmermann-Belsing, T., Brabant, G., Holst, Jens Juul & Feldt-Rasmussen, Ulla, 2003, In: European Journal of Endocrinology. 149, 4, p. 257-71 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cocaine and amphetamine-regulated transcript (CART) is present in hypothalamic neuroendocrine neurons and is related to the hypothalamo-pituitary portal circuit
Larsen, P. J., Seier, V., Fink-Jensen, A., Holst, Jens Juul, Warberg, J. & Vrang, N., 2003, In: Journal of Neuroendocrinology. 15, p. 219-226Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease.
Piche, T., des Varannes, S. B., Sacher-Huvelin, S., Holst, Jens Juul, Cuber, J. C. & Galmiche, J. P., 2003, In: Gastroenterology. 124, 4, p. 894-902 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparisons of leptin, incretins and body composition in obese and lean patients with hypopituitarism and healthy individuals
Mersebach, H., Svendsen, Ole Lander, Holst, Jens Juul, Astrup, A. & Feldt-Rasmussen, Ulla, 2003, In: Clinical Endocrinology. 58, 1, p. 65-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of saturated and monounsaturated fat on postprandial lipemia and incretin responses in type 2 diabetic subjects
Thomsen, C., Storm, H., Holst, Jens Juul & Hermansen, K., 2003, In: Am. J. Clin. Nutr.. 77, p. 605-611Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential regional metabolism of glucagon in anesthetized pigs.
Deacon, Carolyn F., Kelstrup, M., Trebbien, R., Klarskov, L., Olesen, M. & Holst, Jens Juul, 2003, In: American Journal of Physiology: Endocrinology and Metabolism. 285, 3, p. E552-60Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does overnight normalization of plasma glucose by insulin infusion affect assessment of glucose metabolism in type 2 diabetes
Staehr, P., Højlund, K., Hother-Nielsen, O., Holst, Jens Juul & Beck-Nielsen, H., 2003, In: Diabetic Medicine. 20, p. 816-822Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of GLP-2 treatment and antibiotics on gut structure and function during pig weanling diarrhea
Nielsen, T. T., Sangild, Per Torp, Elnif, J., Sorensen, K., Leser, T., Holst, Jens Juul, Hartmann, B., Jensen, B. B. & Hedemann, M. S., 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 161-163 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis.
Staehr, P., Hother-Nielsen, O., Landau, B. R., Chandramouli, V., Holst, Jens Juul & Beck-Nielsen, H., 2003, In: Diabetes. 52, 2, p. 260-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Et æble om dagen
Larsen, P. J., Holst, Jens Juul & Astrup, A., 2003, In: Politiken. 29, 2 p.Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication
- Published
Exogenous GLP-2 has only marginal effects on weaning-induced intestinal adaption in piglets
le Huërou-Luron, I., Petersen, Y. M., Hartmann, B., Holst, Jens Juul & Sangild, Per Torp, 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 164-166 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Functional and immunohistochemical evaluation of porcine neonatal islet-like cell clusters.
Nielsen, T. B., Yderstraede, K. B., Schrøder, H. D., Holst, Jens Juul, Brusgaard, K. & Beck-Nielsen, H., 2003, In: Cell Transplantation. 12, 1, p. 13-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine
Mortensen, K., Christensen, L. L., Holst, Jens Juul & Ørskov, Cathrine, 2003, In: Regulatory Peptides. 114, 2-3, p. 189-96 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TNP-fed piglets
Guan, X., Stoll, B., Lu, X., Tappenden, K., Holst, Jens Juul, Hartmann, B. & Burrin, D. G., 2003, In: Today in Medicine. Gastroenterology. 125, p. 136-147Research output: Contribution to journal › Journal article › Research
- Published
Gastric inhibitory polypeptide (GIP) does not inhibit gastric emptying in man
Meier, J. M., Goetze, O., Anstipp, J., Hagemann, D., Holst, Jens Juul, Schmidt, W. E., Gallwitz, B. & Nauck, M. A., 2003, In: Am. J. Physiol.. 16, p. E621-E625Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia
Meier, J. J., Gallwitz, N., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In: Diabetologia. 46, p. 798-801Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1.
Ugleholdt, Randi Kjærsgaard, Zhu, X., Deacon, Carolyn F., Ørskov, Cathrine, Steiner, D. F. & Holst, Jens Juul, 2003, In: Endocrinology. 145, 3, p. 1349-55 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implementation of GLP-1 based therapy of type 2 diabetes mellitus using DPP-IV inhibitors.
Holst, Jens Juul, 2003, In: Advances in Experimental Medicine and Biology. 524, p. 263-79 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin secretion in relation to meal size and body weight in healthy subjects and in people with type 1 and type 2 diabetes mellitus
Vilsbøll, T., Krarup, T., Sonne, J., Madsbad, S., Vølund, A., Juul, A. G. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 2706-2713Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men
Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, F., Madsbad, Sten & Vaag, A. A., 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 6, p. 2775-2783 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development
Petersen, Y. M., Hartmann, B., Holst, Jens Juul, Le Huërou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, 2003, In: Journal of Nutrition. 133, 6, p. 1781-1786 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lower blood glucose, hyperglucagonemia and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice
Gelling, R. W., Du, X. Q., Dichmann, D. S., Rømer, J., Huan, H., Cui, L., Tang, B. L., Holst, Jens Juul, Fledelius, C., Johansen, P. B., Jelicks, L. A., Serup, P., Nishimura, E. & Charron, M. J., 2003, In: Proc Natl Sci. 100, p. 1438-1443Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lower glucose-dependent insulinotropic polypeptide (GIP) response but similar glucagon-like peptide 1 (GLP-1), glycaemic, and insulinaemic response to ancient wheat compared to modern wheat depends on processing
Bakhøj, S., Flint, A., Holst, Jens Juul & Tetens, Inge , 2003, In: European Journal of Clinical Nutrition. 57, 10, p. 1254-1261 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meals with similar energy densities but rich in protein, fat, carbohydrate, or alcohol have different effects on energy expenditure and substrate metabolism but not on appetite and energy intake
Raben, A. B., Agerholm-Larsen, L., Flint, A., Holst, Jens Juul & Astrup, A., 2003, In: American Journal of Clinical Nutrition. 77, 1, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NO has tonic inhibitory, but is not involved in the vagal control or VIP effects on motility of the porcine antrum
Schmidt, P. T., Ørskov, C., Rasmussen, T. N. & Holst, Jens Juul, 2003, In: Scandinavian Journal of Gastroenterology. 38, p. 955-961Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo.
Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2003, In: Advances in Experimental Medicine and Biology. 524, p. 303-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects
Sørensen, L. B., Flint, A., Raben, A. B., Hartmann, B., Holst, Jens Juul & Astrup, A., 2003, In: International Journal of Obesity. 27, 4, p. 450-456 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No reactive hypoglycaemia after subcutaneous administrations of GLP-1 in lean type 2 diabetic patients and in patients with diabeties secondary to chronic pancreatitis
Knop, F., Vilsbøll, T., Larsen, S., Holst, Jens Juul & Krarup, T., 2003, In: Diabetes Care. 26, p. 2581-2587Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normalisation of glucose concentrations and deceleration of gastric emptying of solid meals during intravenous glucagon-like peptide-1 (GLP-1) in patients with type 2 diabetes
Meier, J. J., Gallwitz, B., Salmen, S., Goetze, O., Holst, Jens Juul & Schmidt, W. E., 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 2719-2725Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety
Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Hartmann, B., Holst, Jens Juul & Hellström, P. M., 2003, In: Regul. Pept.. 116, p. 21-25Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prediction of glycemic index in mixed meals
Møller, B. K., Flint, A., Pedersen, D., Raben, A. B., Tetens, I., Holst, Jens Juul & Astrup, A., 2003. 1 p.Research output: Contribution to conference › Paper › Research
- Published
Role of luminal nutrients and endogenous GLP-2 in intestinal adaptation to mid small bowel resection
Dahly, E. M., Gillingham, M. B., Guo, Z., Murali, S. G., Nelson, D. W., Holst, Jens Juul & Ney, D. M., 2003, In: Amer. J. Physiol.. 284, p. G670-G682Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar elimination rates of GLP-1 in obese type 2 diabetic patients and matched healthy subjects
Vilsbøll, T., Krarup, T., Agersø, H. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 220-224Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar insulin secretory response to a gastric inhibitory polypeptide bolus injection at euglycemia in first-degree relatives of patients with type 2 diabetes and control subjects.
Meier, J. J., Nauck, M. A., Siepmann, N., Greulich, M., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2003, In: Metabolism - Clinical and Experimental. 52, 12, p. 1579-85 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency
Jackson, R. S., Creemers, J. W. M., Saraf Faraoqi, I., Raffin-Sanson, M. L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicholl, T. M., Lindley, K. J. & 1 others, , 2003, In: J. Clin. Invest.. 112, p. 1550-1560Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Somatostatin receptors.
Møller, L. N., Stidsen, C. E., Hartmann, B. & Holst, Jens Juul, 2003, In: BBA General Subjects. 1616, 1, p. 1-84 83 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural differences between rye and wheat bread but not total fiber content may explain the lower postprandial insulin response to rye bread
Juntunen, K. S., Laaksonen, D. E., Aitio, K., Niskanen, L. K., Holst, Jens Juul, Savolainen, K. E., Liukkonen, K. H., Poutanen, K. S. & Mykkänen, H. M., 2003, In: Am. J. Clin. Nutr.. 78, p. 957-964Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of GLP-1 on glucose-induced insulin secretion: effect on ß-cells sensitivity in type 2 and non-diabetic subjects
Kjems, L. L., Holst, Jens Juul, Vølund, A. A. & Madsbad, S., 2003, In: Diabetes. 52, p. 380-386Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The pathogenesis of diabetes involves a defective amplication of the late phase insulin response to glucose by GIP - regardless of aetiology and phenotype
Vilsbøll, T., Knop, F., Krarup, T., Johansen, A., Madsbad, S., Larsen, S., Hansen, T., Pedersen, O. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 4897-4903Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP).
Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In: Regulatory Peptides. 113, 1-3, p. 95-100 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Will GLP-1 treatment increase blood pressure? Summary and comment
Holst, Jens Juul, 2003, In: Diabetes Monitor. 15, p. 15-17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects
Vilsbøll, T., Agersø, H., Krarup, T. & Holst, Jens Juul, Jan 2003, In: The Journal of clinical endocrinology and metabolism. 88, 1, p. 220-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects
Kjems, L. L., Holst, Jens Juul, Vølund, A. & Madsbad, Sten, Feb 2003, In: Diabetes. 52, 2, p. 380-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cocaine- and amphetamine-regulated transcript is present in hypothalamic neuroendocrine neurones and is released to the hypothalamic-pituitary portal circuit
Larsen, P. J., Seier, V., Fink-Jensen, Anders, Holst, Jens Juul, Warberg, J. & Vrang, N., Mar 2003, In: Journal of Neuroendocrinology. 15, 3, p. 219-26 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of saturated and monounsaturated fats on postprandial lipemia and glucagon-like peptide 1 responses in patients with type 2 diabetes
Thomsen, C., Storm, H., Holst, Jens Juul & Hermansen, K., Mar 2003, In: Uden navn. 77, 3, p. 605-11 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects
Sørensen, L. B., Flint, A., Raben, Anne, Hartmann, Bolette, Holst, Jens Juul & Astrup, A., Apr 2003, In: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 27, 4, p. 450-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of luminal nutrients and endogenous GLP-2 in intestinal adaptation to mid-small bowel resection
Dahly, E. M., Gillingham, M. B., Guo, Z., Murali, S. G., Nelson, D. W., Holst, Jens Juul & Ney, D. M., Apr 2003, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 284, 4, p. G670-82Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia
Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., Jun 2003, In: Diabetologia. 46, 6, p. 798-801 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus
Vilsbøll, T., Krarup, T., Sonne, J., Madsbad, Sten, Vølund, A., Juul, A. G. & Holst, Jens Juul, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2706-13 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men
Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, Flemming, Madsbad, Sten & Vaag, Allan, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2775-83 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development
Petersen, Y. M., Hartmann, Bolette, Holst, Jens Juul, Le Huerou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, Jun 2003, In: Journal of Nutrition. 133, 6, p. 1781-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes
Meier, J. J., Gallwitz, B., Salmen, S., Goetze, O., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2719-25 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2-mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TPN-fed piglets 1
Guan, X., Stoll, B., Lu, X., Tappenden, K. A., Holst, Jens Juul, Hartmann, Bolette & Burrin, D. G., Jul 2003, In: Gastroenterology. 125, 1, p. 136-47 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects
Vilsbøll, T., Krarup, T., Madsbad, Sten & Holst, Jens Juul, 15 Jul 2003, In: Regulatory Peptides. 114, 2-3, p. 115-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absence of a memory effect for the insulinotropic action of glucagon-like peptide 1 (GLP-1) in healthy volunteers
Meier, S., Hücking, K., Ritzel, R., Holst, Jens Juul, Schmiegel, W. H. & Nauck, M. A., Sep 2003, In: Hormone and Metabolic Research. Supplement. 35, 9, p. 551-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nitric oxide has tonic inhibitory effect, but is not involved in the vagal control or VIP effects on motility of the porcine antrum
Schmidt, P. T., Ørskov, Cathrine, Rasmussen, T. N. & Holst, Jens Juul, Sep 2003, In: Scandinavian Journal of Gastroenterology. 38, 9, p. 955-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans
Ahrén, B., Holst, Jens Juul & Mari, A., Oct 2003, In: Diabetes Care. Supplement. 26, 10, p. 2860-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency
Jackson, R. S., Creemers, J. W. M., Farooqi, I. S., Raffin-Sanson, M-L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicole, T. M., Milla, P. J. & 2 others, , Nov 2003, In: The Journal of Clinical Investigation. 112, 10, p. 1550-60 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural differences between rye and wheat breads but not total fiber content may explain the lower postprandial insulin response to rye bread
Juntunen, K. S., Laaksonen, D. E., Autio, K., Niskanen, L. K., Holst, Jens Juul, Savolainen, K. E., Liukkonen, K., Poutanen, K. S. & Mykkänen, H. M., Nov 2003, In: Uden navn. 78, 5, p. 957-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety
Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Hartmann, Bolette, Holst, Jens Juul & Hellström, P. M., 15 Nov 2003, In: Regulatory Peptides. 116, 1-3, p. 21-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of gastrointestinal hormones in postprandial reduction of bone resorption
Henriksen, D. B., Alexandersen, P., Bjarnason, N. H., Vilsbøll, Tina, Hartmann, B., Henriksen, E. E. G., Byrjalsen, I., Krarup, T., Holst, Jens Juul & Christiansen, C., 1 Dec 2003, In: J Bone Miner Res. 18, 12, p. 2180-2190 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Additive effects of glucagon-like peptide 1 and pioglitazone in patients with type 2 diabetes.
Olsen, Ane Mette Zander, Christiansen, A., Madsbad, Sten & Holst, Jens Juul, 2004, In: Diabetes Care. 27, 8, p. 1910-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anti-hyperglycemi effects of stevioside in type 2 diabetic subjects
Gregersen, S., Jeppesen, P. B., Holst, Jens Juul & Hermansen, K., 2004, In: Metabolism. 53, p. 73-76Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide-1
Nauck, M. A., Walberg, J., Vethacke, A., El-Quaghlidi, A., Senkal, M., Holst, Jens Juul, Gallwitz, J. B., Schmidt, W. E. & Schmiegel, W., 2004, In: Regul. Pept.. 118, p. 89-97Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholecystokinin inhibits gastrin secretion independent of paracrine somatostatin secretion in the pig
Schmidt, P. T., Hansen, L., Hilsted, L. & Holst, Jens Juul, 2004, In: Scandinavian Journal of Gastroenterology. 39, p. 217-221Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Depletion of mucosal substance P in acute otitis media.
Cayé-Thomasen, Per, Schmidt, P. T., Hermansson, A., Holst, Jens Juul & Thomsen, J., 2004, In: Acta Oto-Laryngologica. 124, 7, p. 794-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Different effects of whole milk and a fermented milk with the same fat and lactose content on gastric emptying and postprandial lipaemia, but not on glycaemic response and appetite
Sanggaard, K. M., Holst, Jens Juul, Rehfeld, J. F., Sandström, B. & Tholstrup, T., 2004, In: Br.J.Nutr.. 92, 92, p. 447-459Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors
Hansotia, T., Baggio, L. L., Delmeire, D., Hinke, S. A., Yamada, Y., Tsukiyama, K., Seino, Y., Holst, Jens Juul, Schuit, F. & Drucker, D. J., 2004, In: Diabetes. 53, p. 1326-1335Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of glucagon-like peptide-1 on endothelial function in type 2 diabetes patients with stable coronary artery disease.
Nyström, T., Gutniak, M. K., Zhang, Q., Zhang, F., Holst, Jens Juul, Ahrén, B. & Sjöholm, A., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 6, p. E1209-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of low vs. high glycemic index diets on appetite and energy expenditure
Sloth, B., Krog-Mikkelsen, I., Dimitrov, D., Holst, Jens Juul, Flint, A., Tetens, Inge , Björck, I., Elmstahl, H., Astrup, A. & Raben, A., 2004. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Enhancing insulin secretion: novel approaches to glucose control
Holst, Jens Juul, 2004, In: Diabetes Voice. 49, p. 20-22Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteroglucagon
Holst, Jens Juul, 2004, In Encyclopedia of Gatroenterology. USA: Elsevier, p. 709-715Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
- Published
Ethanol with a mixed meal decreases the incretin levels early postprandially and increases postprandial lipemia in type 2 diabetic patients
Dalgaard, M., Thomsen, C., Rasmussen, B. M., Holst, Jens Juul & Hermansen, K., 2004, In: Metabolism. 53, p. 77-83Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 levels in human infants with intestinal dysfunction
Sigalet, D. L., Martin, G., Meddings, J., Hartmann, B. & Holst, Jens Juul, 2004, In: Pediatric Research. 56, p. 371-376Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 and inhibitors of dipeptidyl peptidase IV in the treatment of type 2 diabetes mellitus.
Holst, Jens Juul & Deacon, Carolyn F., 2004, In: Current Opinion in Pharmacology. 4, 6, p. 589-96 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide- 1 secretion is influenced by perfusate glucose concentration and a feedback mechanism involving somatostatin in isolated perfused porcine ileum
Hansen, L., Hartmann, B., Mineo, H. & Holst, Jens Juul, 2004, In: Regul. Pept.. 118, p. 11-18Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 (GLP-2) inhibits gastric emptying and promotes satiety in man, but is not as potent as Glucagon-like peptide-1 (GLP-1)
Nagell, C. F., Wettergren, A., Fog Pedersen, J., Mortensen, D. & Holst, Jens Juul, 2004, In: Scandinavian Journal of Gastroenterology. 39, p. 353-358Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycemia and insulinemia in healthy subjects after lactose equivalent meals of milk and other food proteins: on the role of plasma amino acids and incretins
Nilsson, M., Stenberg, M., Frid, A. H., Holst, Jens Juul & Björck, I., 2004, In: Am. J. Clin. Nutr.. 80, p. 1246-1253Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretins, insulin secretion and type 2 diabetes mellitus
Vilsboll, T. & Holst, Jens Juul, 2004, In: Diabetologia. 47, p. 654-662Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibitors of dipeptidyl peptidase IV: a novel approach for the prevention and treatment of Type 2 diabetes?
Deacon, Carolyn F., Ahrén, B. & Holst, Jens Juul, 2004, In: Expert Opinion on Investigational Drugs. 13, 9, p. 1091-102 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin secretion and incretin hormones after oral glucose in impaired glucose tolerance
Rask, E., Olsson, T., Söderberg, S., Holst, Jens Juul, Tura, A., Pacini, G. & Ahren, B., 2004, In: Metabolism. 53, p. 624-631Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin secretion in lipodystrophic HIV-infected patients is associated with high levels of nonglucose secretagogues and insulin resistance of beta-cells.
Haugaard, S. B., Andersen, Ove, Storgaard, H., Dela, Flemming, Holst, Jens Juul, Iversen, J., Nielsen, J. O. & Madsbad, Sten, 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 4, p. E677-85 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intravenous glucagon-like peptide 1 (GLP-1) normalizes blood glucose after major surgery in patients with type 2 diabetes
Meier, J. J., Weyhe, D., Michaely, M., Senkal, M., Zumtobel, V., Nauck, M. A., Holst, Jens Juul, Schmidt, W. E. & Gallwitz, B., 2004, In: Critical Care Medicine. 32, p. 848-851Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Milrinone efficiently potentiates insulin secretion induced by orally but not intravenously administered glucose in C57BL6J mice
Degerman, E., Manganiello, V., Holst, Jens Juul & Ahren, B., 2004, In: Eur. J. Pharmacol.. 498, p. 319-323Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neural regulation of glucagon-like peptide- 1 secretion in pigs
Hansen, L., Lampert, S., Mineo, H. & Holst, Jens Juul, 2004, In: Am. J. Physiol.. 287, p. E939-E947Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neutral endopeptidase 24.11 is important for the degradation of both endogenous and exogenous glucagon in anesthetized pigs.
Trebbien, R., Klarskov, L., Olesen, M., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 3, p. E431-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the physiology of GIP and GLP-1
Holst, Jens Juul, 2004, In: Horm Metab Res. 36, p. 747-754Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Onset of small intestinal atrophy is associated with reduced intestinal blod flow in TNP-fed neonatal piglets
Niinikoski, H., Stoll, B., Guam, X., Kansagra, K., Lambert, B., Hartmann, B., Holst, Jens Juul & Burrin, D. G., 2004, In: Journal of Nutrition. 134, p. 1467-1474Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens
Paris, M. C. J., Fuller, P. J., Taylor, R. G., Nagy, E., Sourial, M., Catto-Smith, T., Hartmann, B., Holst, Jens Juul & Bines, J. E., 2004, In: Dig. Dis. Sci.. 49, p. 1688-1695Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prandial subcutaneous injections of glucagons-like peptide- 1 cause weight loss in obese human subjects
Näslund, E., King, N., Mansten, S., Adner, N., Holst, Jens Juul, Gutniak, M. & Hellström, P., 2004, In: Br.J.Nutr.. 91, p. 439-446Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Göttingen minipig after oral glucose in vivo and in the perfused pancreas
Larsen, M. O., Rolin, B., Gotfredsen, C. F., Carr, R. D. & Holst, Jens Juul, 2004, In: Diabetologia. 47, p. 1873-1878Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2.
Henriksen, D. B., Alexandersen, P., Byrjalsen, I., Hartmann, B., Bone, H. G., Christiansen, C. & Holst, Jens Juul, 2004, In: Bone. 34, 1, p. 140-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans.
Holst, Jens Juul & Gromada, J., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 2, p. E199-206Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes.
Nauck, M. A., El-Ouaghlidi, A., Gabrys, B., Hücking, K., Holst, Jens Juul, Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Meier, J. J., 2004, In: Regulatory Peptides. 122, 3, p. 209-17 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects.
Meier, J. J., Nauck, M. A., Kranz, D., Holst, Jens Juul, Deacon, Carolyn F., Gaeckler, D., Schmidt, W. E. & Gallwitz, B., 2004, In: Diabetes. 53, 3, p. 654-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar gastric emptying but greater gastric secretion and GIP release after the ingestion of peptide hydrolysates in man
Calbet, J. A. L. & Holst, Jens Juul, 2004, In: Eur J Nutrition. 43, p. 127-139Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stimulation of insulin secretion by intravenous bolus injection and continuous infusion of gastric inhibitory polypeptide in patients with type 2 diabetes and healthy control subjects.
Meier, J. J., Gallwitz, B., Kask, B., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2004, In: Diabetes. 53 Suppl 3, p. S220-4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation following and 80% jejunoileal resection in neonatal pigs
Bartholome, A. L., Albin, D. M., Baker, D. H., Holst, Jens Juul & Tappenden, K. A., 2004, In: J Parenter Enteral Nutr. 28, p. 210-223Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin approach for diabetes treatment: modulation of islet hormone release by GLP-1 agonism.
Holst, Jens Juul & Ørskov, Cathrine, 2004, In: Diabetes. 53 Suppl 3, p. S197-204Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ¤use of glycaemic index tables to predict glycaemic index of composite breakfast meals
Flint, A., Møller, B. K., Raben, Anne, Pedersen, D., Tetens, I., Holst, Jens Juul & Astrup, A., 2004, In: British Journal of Nutrition. 91, 6, p. 979-989 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors.
Holst, Jens Juul, 2004, In: Expert Opinion on Emerging Drugs. 9, 1, p. 155-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antihyperglycemic effects of stevioside in type 2 diabetic subjects
Gregersen, S., Jeppesen, P. B., Holst, Jens Juul & Hermansen, K., Jan 2004, In: Metabolism. 53, 1, p. 73-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholecystokinin inhibits gastrin secretion independently of paracrine somatostatin secretion in the pig
Schmidt, P. T., Hansen, L., Hilsted, Linda & Holst, Jens Juul, Mar 2004, In: Scandinavian Journal of Gastroenterology. 39, 3, p. 217-21 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretins, insulin secretion and Type 2 diabetes mellitus
Vilsbøll, T. & Holst, Jens Juul, Mar 2004, In: Diabetologia. 47, 3, p. 357-66 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intravenous glucagon-like peptide 1 normalizes blood glucose after major surgery in patients with type 2 diabetes
Meier, J. J., Weyhe, D., Michaely, M., Senkal, M., Zumtobel, V., Nauck, M. A., Holst, Jens Juul, Schmidt, W. E. & Gallwitz, B., Mar 2004, In: New Horizons (Baltimore). 32, 3, p. 848-51 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prandial subcutaneous injections of glucagon-like peptide-1 cause weight loss in obese human subjects
Näslund, E., King, N., Mansten, S., Adner, N., Holst, Jens Juul, Gutniak, M. & Hellström, P. M., Mar 2004, In: The British Journal of Nutrition. 91, 3, p. 439-46 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric inhibitory polypeptide does not inhibit gastric emptying in humans
Meier, J. J., Goetze, O., Anstipp, J., Hagemann, D., Holst, Jens Juul, Schmidt, W. E., Gallwitz, B. & Nauck, M. A., Apr 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 286, 4, p. E621-5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 inhibits antral emptying in man, but is not as potent as glucagon-like peptide-1
Nagell, C. F., Wettergren, A., Pedersen, J. F., Mortensen, D. & Holst, Jens Juul, Apr 2004, In: Scandinavian Journal of Gastroenterology. 39, 4, p. 353-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood glucose control in healthy subject and patients receiving intravenous glucose infusion or total parenteral nutrition using glucagon-like peptide 1
Nauck, M. A., Walberg, J., Vethacke, A., El-Ouaghlidi, A., Senkal, M., Holst, Jens Juul, Gallwitz, B., Gallwitz, J. B., Schmidt, W. E. & Schmiegel, W., 15 Apr 2004, In: Regulatory Peptides. 118, 1-2, p. 89-97 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 secretion is influenced by perfusate glucose concentration and by a feedback mechanism involving somatostatin in isolated perfused porcine ileum
Hansen, L., Hartmann, Bolette, Mineo, H. & Holst, Jens Juul, 15 Apr 2004, In: Regulatory Peptides. 118, 1-2, p. 11-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors
Hansotia, T., Baggio, L. L., Delmeire, D., Hinke, S. A., Yamada, Y., Tsukiyama, K., Seino, Y., Holst, Jens Juul, Schuit, F. & Drucker, D. J., May 2004, In: Diabetes. 53, 5, p. 1326-35 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance
Rask, E., Olsson, T., Söderberg, S., Holst Jj, J. J., Tura, A., Pacini, G., Ahrén, B. & Holst, Jens Juul, May 2004, In: Metabolism. 53, 5, p. 624-31 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying, gastric secretion and enterogastrone response after administration of milk proteins or their peptide hydrolysates in humans
Calbet, J. A. L. & Holst, Jens Juul, Jun 2004, In: European Journal of Nutrition. 43, 3, p. 127-39 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets
Niinikoski, H., Stoll, B., Guan, X., Kansagra, K., Lambert, B. D., Stephens, J., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Jun 2004, In: Journal of Nutrition. 134, 6, p. 1467-74 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 (GLP-2) accelerates the growth of colonic neoplasms in mice
Thulesen, J., Hartmann, Bolette, Hare, K. J., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Aug 2004, In: Gut. 53, 8, p. 1145-1150 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets
Bartholome, A. L., Albin, D. M., Baker, D. H., Holst, Jens Juul & Tappenden, K. A., 5 Aug 2004, In: Journal of Parenteral and Enteral Nutrition. 28, 4, p. 210-22; discussion 222-3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 levels in infants with intestinal dysfunction
Sigalet, D. L., Martin, G., Meddings, J., Hartman, B. & Holst, Jens Juul, Sep 2004, In: Pediatric Research. 56, 3, p. 371-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens
Paris, M. C., Fuller, P. J., Carstensen, Bendix, Nagy, E., Taylor, R. G., Sourial, M., Holst, Jens Juul, Hartmann, Bolette & Binesm, J. E., Oct 2004, In: Digestive Diseases and Sciences. 49, 10, p. 1688-95 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycemia and insulinemia in healthy subjects after lactose-equivalent meals of milk and other food proteins: the role of plasma amino acids and incretins
Nilsson, M., Stenberg, M., Frid, A. H., Holst, Jens Juul & Björck, I. M. E., Nov 2004, In: Uden navn. 80, 5, p. 1246-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neural regulation of glucagon-like peptide-1 secretion in pigs
Hansen, L., Lampert, S., Mineo, H. & Holst, Jens Juul, Nov 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 5, p. E939-47Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Alpha-Glucosidase inhibition (Acarbose) fails to enhance secretion of glucagons-like peptide 1(7-36 amide) and to delay gastric emptying in type 2 diabetic patients
Hücking, K., Kostic, Z., Pox, C., Ritzel, R., Holst, Jens Juul, Schmiegel, W. & Nauck, M. A., 2005, In: Diabet. Med.. 22, p. 470-476Research output: Contribution to journal › Journal article › Research
- Published
Defective glucose and lipid metabolism in human immunodeficiency virus-infected patients with lipodystrophy involve liver, muscle tissue and pancreatic beta-cells.
Haugaard, S. B., Andersen, Ove, Dela, Flemming, Holst, Jens Juul, Storgaard, H., Fenger, M., Iversen, J., Madsbad, Sten, Haugaard, S. B., Andersen, Ove, Dela, F., Holst, J. J., Storgaard, H., Fenger, M., Iversen, J. & Madsbad, Sten, 2005, In: European Journal of Endocrinology. 152, 1, p. 103-112 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential postprandial lipoprotein responses in type 2 diabetic men with and without clinical evidence of a former myocardial infarction.
Carstensen, M., Thomsen, C., Gotzsche, O., Holst, Jens Juul, Schrezenmeir, J. & Hermansen, K., 2005, In: The review of diabetic studies : RDS. 1, 4, p. 175-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase IV inhibitors: a promising new therapeutic approach for the management of type 2 diabetes.
Deacon, Carolyn F. & Holst, Jens Juul, 2005, In: International Journal of Biochemistry & Cell Biology. 38, 5-6, p. 831-44 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility.
Miki, T., Minami, K., Shinozaki, H., Matsumura, K., Saraya, A., Ikeda, H., Yamada, Y., Holst, Jens Juul & Seino, S., 2005, In: Diabetes. 54, 4, p. 1056-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of whey on blood glucose and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects.
Frid, A. H., Nilsson, M., Holst, Jens Juul & Björck, I. M. E., 2005, In: American Journal of Clinical Nutrition. 82, 1, p. 69-75 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhanced glucagon-like peptide- 1 (GLP-1) response to oral glucose in glucose intolerant HIV-infected patients on antiretroviral therapy
Andersen, O., Haugaard, S. B., Holst, Jens Juul, Deacon, Carolyn F., Iversen, J., Andersen, U. B., Nielsen, J. O. & Madsbad, S., 2005, In: HIV Medicine. 6, p. 91-98Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteral feeding without pancreatic stimulation.
Kaushik, N., Pietraszewski, M., Holst, Jens Juul & O'Keefe, S. J. D., 2005, In: Pancreas. 31, 4, p. 353-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erythromycin antagonises the deceleration of gastric emptying by glucagon-like peptide-1 (GLP)-1 and unmasks its insulinotropic effect in healthy subjects
Meier, J. J., Kemmeries, G., Holst, Jens Juul & Nauck, M. A., 2005, In: Diabetes. 54, p. 2212-2218Research output: Contribution to journal › Journal article › Research
- Published
Evidence for an endocrine pancreatico-gastric axis: The role of pancreatic polypeptide in gastric emptying and short term metabolic control
Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Holst, Jens Juul, Hilsted, L. & Hellström, P. M., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 5241-5246Research output: Contribution to journal › Journal article › Research
- Published
Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes
Torekov, Signe Sørensen, Larsen, L. H., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Holst, Jens Juul, Madsen, O. D., Hansen, Torben & Pedersen, Oluf Borbye, 2005, In: Diabetes. 54, 7, p. 2261-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence of an association between the Arg72-allele of the peptide YY (PYY) and increased risk of type 2 diabetes
Torekov, S. S., Larsen, L. H., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Holst, Jens Juul, Madsen, O. D., Hansen, T. & Pedersen, O., 2005, In: Diabetes. 54, p. 2261-2265Research output: Contribution to journal › Journal article › Research
- Published
Exenatide augments first and second phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes
Fehse, F., Trautmann, M., Holst, Jens Juul, Halseth, A. E., Nanyakkara, N., Nielsen, L., Fineman, M. S. D., Kim, D. D. & Nauck, M. A., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 5991-5997Research output: Contribution to journal › Journal article › Research
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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