Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon
Research output: Contribution to journal › Journal article › peer-review
Glucagon-like peptide 2 (GLP-2) is intestinotrophic, antisecretory, and transit-modulating in rodents, and it is mainly secreted from the intestinal mucosa of the terminal ileum and colon after food ingestion. We assessed the effect of GLP-2 on the gastrointestinal function in patients without a terminal ileum and colon who have functional short-bowel syndrome with severe malabsorption of wet weight (>1.5 kg/day) and energy (>2.3 MJ/day) and no postprandial secretion of GLP-2.
|Number of pages||10|
|Publication status||Published - Mar 2001|
- Adult, Body Composition, Body Weight, Creatinine, Female, Gastrointestinal Hormones, Gastrointestinal Transit, Glucagon-Like Peptide 2, Glucagon-Like Peptides, Hormones, Humans, Injections, Subcutaneous, Intestinal Absorption, Intestines, Male, Middle Aged, Nutritional Status, Patient Compliance, Peptides, Short Bowel Syndrome