Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon
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Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon. / Jeppesen, P B; Hartmann, B; Thulesen, J; Graff, J; Lohmann, J; Hansen, B S; Tofteng, F; Poulsen, Steen Seier; Madsen, J L; Holst, J J; Mortensen, P B.
In: Gastroenterology, Vol. 120, No. 4, 03.2001, p. 806-815.Research output: Contribution to journal › Journal article › peer-review
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TY - JOUR
T1 - Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon
AU - Jeppesen, P B
AU - Hartmann, B
AU - Thulesen, J
AU - Graff, J
AU - Lohmann, J
AU - Hansen, B S
AU - Tofteng, F
AU - Poulsen, Steen Seier
AU - Madsen, J L
AU - Holst, J J
AU - Mortensen, P B
PY - 2001/3
Y1 - 2001/3
N2 - Glucagon-like peptide 2 (GLP-2) is intestinotrophic, antisecretory, and transit-modulating in rodents, and it is mainly secreted from the intestinal mucosa of the terminal ileum and colon after food ingestion. We assessed the effect of GLP-2 on the gastrointestinal function in patients without a terminal ileum and colon who have functional short-bowel syndrome with severe malabsorption of wet weight (>1.5 kg/day) and energy (>2.3 MJ/day) and no postprandial secretion of GLP-2.
AB - Glucagon-like peptide 2 (GLP-2) is intestinotrophic, antisecretory, and transit-modulating in rodents, and it is mainly secreted from the intestinal mucosa of the terminal ileum and colon after food ingestion. We assessed the effect of GLP-2 on the gastrointestinal function in patients without a terminal ileum and colon who have functional short-bowel syndrome with severe malabsorption of wet weight (>1.5 kg/day) and energy (>2.3 MJ/day) and no postprandial secretion of GLP-2.
KW - Adult
KW - Body Composition
KW - Body Weight
KW - Creatinine
KW - Female
KW - Gastrointestinal Hormones
KW - Gastrointestinal Transit
KW - Glucagon-Like Peptide 2
KW - Glucagon-Like Peptides
KW - Hormones
KW - Humans
KW - Injections, Subcutaneous
KW - Intestinal Absorption
KW - Intestines
KW - Male
KW - Middle Aged
KW - Nutritional Status
KW - Patient Compliance
KW - Peptides
KW - Short Bowel Syndrome
M3 - Journal article
C2 - 11231933
VL - 120
SP - 806
EP - 815
JO - Gastroenterology
JF - Gastroenterology
SN - 0016-5085
IS - 4
ER -
ID: 168197