Christina Christoffersen

Christina Christoffersen

Associate Professor


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  1. Published

    (18)F-FDG PET imaging of murine atherosclerosis: association with gene expression of key molecular markers

    Hag, Anne Mette Fisker, Pedersen, S. F., Christoffersen, Christina, Binderup, Tina, Wessel, Mette Munk, Jørgensen, Jesper Tranekjær, Skovgaard, D., Ripa, Rasmus Sejersten & Kjær, Andreas, 2012, In: P L o S One. 7, 11, p. e50908

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A Novel Perspective on the ApoM-S1P Axis, Highlighting the Metabolism of ApoM and Its Role in Liver Fibrosis and Neuroinflammation

    Hajny, Stefan & Christoffersen, Christina, 27 Jul 2017, In: International Journal of Molecular Sciences. 18, 8, 19 p., 1636.

    Research output: Contribution to journal › Review › Research › peer-review

  3. Published

    Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair

    Ding, B. S., Yang, D., Swendeman, S. L., Christoffersen, Christina, Nielsen, L. B., Friedman, S. L., Powell, C. A., Hla, T. & Cao, Z., 2020, In: Developmental Cell. 53, 6, p. 677-690

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Altered Metabolism of LDL in the Arterial Wall Precedes Atherosclerosis Regression

    Bartels, Emil Daniel, Christoffersen, Christina, Lindholm, M. W. & Nielsen, L. B., 2015, In: Circulation Research. 117, p. 933-942 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    ApoB and apoM - New aspects of lipoprotein biology in uremia-induced atherosclerosis

    Christoffersen, Christina, Bartels, Emil Daniel, Pedersen, A. A., Nielsen, L. B. & Pedersen, T. X., Dec 2017, In: European Journal of Pharmacology. 816, p. 154-160 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    ApoM: gene regulation and effects on HDL metabolism

    Nielsen, L. B., Christoffersen, Christina, Ahnström, J. & Dahlbäck, B., 2009, In: Trends in Endocrinology and Metabolism. 20, 2, p. 66-71 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs

    Shim, J., Poulsen, C. B., Hagensen, M. K., Larsen, T., Heegaard, P. M. H., Christoffersen, Christina, Bolund, L., Schmidt, M., Liu, Y., Li, J., Li, R., Callesen, H., Bentzon, J. F. & Sørensen, C. B., 2017, In: JACC: Basic to Translational Science. 2, 5, p. 591-600 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Apolipoprotein M: Impact on lipoprotein metabolism and vascular function

    Christoffersen, Christina, 2014, Frederiksberg: Det Sundhedsvidenskabelige Fakultet, Københavns Universitet. 118 p.

    Research output: Book/Report › Doctoral thesis › Research

  9. Published

    Apolipoprotein M: progress in understanding its regulation and metabolic functions

    Christoffersen, Christina, Dahlbäck, B. & Nielsen, L. B., 2006, In: Scandinavian Journal of Clinical & Laboratory Investigation. 66, 7, p. 631-7 7 p.

    Research output: Contribution to journal › Journal article › Research

  10. Published

    Apolipoprotein M: bridging HDL and endothelial function

    Christoffersen, Christina & Nielsen, L. B., Aug 2013, In: Current Opinion in Lipidology. 24, 4, p. 295-300 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Apolipoprotein M - a new biomarker in sepsis

    Christoffersen, Christina & Nielsen, L. B., 2012, In: Critical Care (Online Edition). 16, 3, p. 126

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Apolipoprotein M Attenuates Anthracycline Cardiotoxicity and Lysosomal Injury

    Guo, Z., Valenzuela Ripoll, C., Picataggi, A., Rawnsley, D. R., Ozcan, M., Chirinos, J. A., Chendamarai, E., Girardi, A., Riehl, T., Evie, H., Diab, A., Kovacs, A., Hyrc, K., Ma, X., Asnani, A., Shewale, S. V., Scherrer-Crosbie, M., Cowart, L. A., Parks, J. S., Zhao, L. & 14 others, Gordon, D., Ramirez-Valle, F., Margulies, K. B., Cappola, T. P., Desai, A. A., Pedersen, L. N., Bergom, C., Stitziel, N. O., Rettig, M. P., DiPersio, J. F., Hajny, Stefan, Christoffersen, Christina, Diwan, A. & Javaheri, A., 2023, In: JACC: Basic to Translational Science. 8, 3, p. 340-355

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Apolipoprotein M and Risk of Type 2 Diabetes

    Hajny, Stefan, Christoffersen, M., Dalila, N., Nielsen, L. B., Tybjærg-Hansen, Anne & Christoffersen, Christina, 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 9, p. 3046-3057

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Apolipoprotein M and Sphingosine-1-Phosphate Receptor 1 Promote the Transendothelial Transport of High-Density Lipoprotein

    Velagapudi, S., Rohrer, L., Poti, F., Feuerborn, R., Perisa, D., Wang, D., Panteloglou, G., Potapenko, A., Yalcinkaya, M., Hulsmeier, A. J., Hesse, B., Lukasz, A., Liu, M., Parks, J. S., Christoffersen, Christina, Stoffel, M., Simoni, M., Nofer, J. & von Eckardstein, A., 2021, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 41, 10, p. E468-E479 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Apolipoprotein M and its impact on endothelial dysfunction and inflammation in the cardiovascular system

    Yao Mattisson, I. & Christoffersen, Christina, 2021, In: Atherosclerosis. 334, p. 76-84

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL

    Elsøe, S., Ahnström, J., Christoffersen, Christina, Hoofnagle, A. N., Plomgaard, Peter Stendahl, Heinecke, J. W., Binder, C. J., Björkbacka, H., Dahlbäck, B. & Nielsen, L. B., 2012, In: Atherosclerosis. 221, 1, p. 91-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Apolipoprotein M in lipid metabolism and cardiometabolic diseases

    Borup, A., Christensen, P. M., Nielsen, L. B. & Christoffersen, Christina, Feb 2015, In: Current Opinion in Lipidology. 26, 1, p. 48-55 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Apolipoprotein M in patients with chronic kidney disease

    Sørensen, I. M., Bertelsen, M., Freese, E., Lindhard, K., Ullum, H., Feldt-Rasmussen, Bo, Nielsen, L. B., Christoffersen, Christina & Bro, S., 2018, In: Atherosclerosis. 275, p. 304-311

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes

    Christensen, P. M., Bosteen, M. H., Hajny, Stefan, Nielsen, L. B. & Christoffersen, Christina, 8 Nov 2017, In: Scientific Reports. 7, 10 p., 14983.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Apolipoprotein M promotes mobilization of cellular cholesterol in vivo

    Elsøe, S., Christoffersen, Christina, Luchoomun, J., Turner, S. & Nielsen, L. B., Jul 2013, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1831, 7, p. 1287-92 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Apolipoprotein M-A Marker or an Active Player in Type II Diabetes?

    Christoffersen, Christina, 2021, In: Frontiers in Endocrinology. 12, 10 p., 665393.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Apolipoprotein M-bound sphingosine-1-phosphate regulates blood-brain barrier paracellular permeability and transcytosis

    Mathiesen Janiurek, M., Soylu-Kucharz, R., Christoffersen, Christina, Kucharz, Krzysztof & Lauritzen, Martin, 25 Nov 2019, In: eLife. 8, 22 p., e49405.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Apolipoprotein M/sphingosine-1-phosphate: novel effects on lipids, inflammation and kidney biology

    Bisgaard, L. S. & Christoffersen, Christina, 2019, In: Current Opinion in Lipidology. 30, 3, p. 212-217

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Apolipoprotein M: Structure and Function

    Dahlback, B., Ahnstrom, J., Christoffersen, Christina & Nielsen, L. B., 2008, In: Future Lipidology. 3, p. 495-503

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Association between plasma apolipoprotein M and cardiac autonomic neuropathy in type 1 diabetes

    Safi, M., Borup, A., Stevns Hansen, C., Rossing, Peter, Thorsten Jensen, M. & Christoffersen, Christina, 2022, In: Diabetes Research and Clinical Practice. 189, 7 p., 109943.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Association of apolipoprotein M and sphingosine-1-phosphate with brown adipose tissue after cold exposure in humans

    Borup, A., Donkin, I., Boon, M. R., Frydland, M., Martinez-Tellez, B., Loft, A., Keller, S. H., Kjær, Andreas, Kjærgaard, Jesper, Hassager, Christian, Barrès, Romain, Rensen, P. C. N. & Christoffersen, Christina, 2022, In: Scientific Reports. 12, 1, 11 p., 18753.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Associations Between Albuminuria, Estimated GFR and Cardiac Phenotype in a Cohort with Chronic Kidney Disease: The CPH-CKD ECHO Study

    Landler, N. E., Olsen, F. J., Christensen, J., Bro, S., Feldt-Rasmussen, Bo, Hansen, Ditte, Kamper, A., Christoffersen, Christina, Ballegaard, E. L. F., Sørensen, I. M. H., Bjergfelt, S. S., Seidelin, E., Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2022, In: Journal of Cardiac Failure. 28, 11, p. 1615-1627 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. E-pub ahead of print

    Blood biomarkers improve the prediction of prevalent and incident severe chronic kidney disease

    Nusinovici, S., Li, H., Chong, C., Yu, M., Sørensen, I. M. H., Bisgaard, Line, Christoffersen, Christina, Bro, S., Liu, S., Liu, J. J., Chi, L. S., Wong, T. Y., Tan, G. S. W., Cheng, C. Y. & Sabanayagam, C., 2024, (E-pub ahead of print) In: Journal of Nephrology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Cardiac lipid accumulation associated with diastolic dysfunction in obese mice

    Christoffersen, Christina, Bollano, E., Lindegaard, M. L. S., Bartels, Emil Daniel, Goetze, Jens P. , Andersen, C. B. & Nielsen, L. B., Aug 2003, In: Molecular Endocrinology. 144, 8, p. 3483-90 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Cardiac natriuretic peptide gene expression and plasma concentrations during the first 72 hours of life in piglets

    Smith, J., Christoffersen, Christina, Nørgaard, L. M., Olsen, Lisbeth Høier, Vejlstrup, N. G., Andersen, C. B. & Gøtze, J. P., 2013, In: Endocrinology. 154, 5, p. 1864-1872 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Cardiovascular prognostic value of echocardiography and N terminal pro B-type natriuretic peptide in type 1 diabetes: The Thousand and 1 Study

    Rørth, R., Jørgensen, P. G., Andersen, H. U., Christoffersen, Christina, Goetze, Jens P. , Køber, Lars Valeur, Rossing, Peter & bqn654, bqn654, 2020, In: European Journal of Endocrinology. 182, 5, p. 481-488

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Carotid plaque thickness is increased in chronic kidney disease and associated with carotid and coronary calcification

    Bjergfelt, S. S., Sørensen, I. M. H., Hjortkjær, H., Landler, N., Ballegaard, E. L. F., Biering-Sørensen, Tor, Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Sillesen, Henrik, Christoffersen, Christina & Bro, S., 2021, In: PLoS ONE. 16, 16 p., e0260417.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Chamber-dependent expression of brain natriuretic peptide and its mRNA in normal and diabetic pig heart

    Christoffersen, Christina, Goetze, Jens P. , Bartels, Emil Daniel, Larsen, T. M., Ribel, U., Rehfeld, Jens Frederik, Rolin, B. & Nielsen, L. B., Jul 2002, In: Hypertension. 40, 1, p. 54-60 7 p.

    Research output: Contribution to journal › Journal article › Research

  34. Published

    Circulating cord blood HDL-S1P complex preserves the integrity of the feto-placental vasculature

    Del Gaudio, I., Sreckovic, I., Zardoya-Laguardia, P., Bernhart, E., Christoffersen, Christina, Frank, S., Marsche, G., Illanes, S. E. & Wadsack, C., 2020, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1865, 4, 11 p., 158632.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Coronary and extra-coronary artery calcium scores as predictors of cardiovascular events and mortality in chronic kidney disease stages 1-5: a prospective cohort study

    Sorensen, I. M. H., Bjergfelt, S. S., Hjortkjær, H. O., Kofoed, Klaus Fuglsang, Lange, Theis, Feldt-Rasmussen, Bo, Christoffersen, Christina & Bro, S., 2023, In: Nephrology Dialysis Transplantation. 38, 5, p. 1227–1239 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Diabetes and the endocrine heart

    Christoffersen, Christina, Hunter, I., Jensen, Asger Lundorff & Goetze, Jens P. , Oct 2007, In: European Heart Journal. 28, 20, p. 2427-9 3 p.

    Research output: Contribution to journal › Editorial › Research

  37. Published

    Diabetes with poor glycaemic control does not promote atherosclerosis in genetically modified hypercholesterolaemic minipigs

    Al-Mashhadi, R. H., Bjørklund, M. M., Mortensen, M. B., Christoffersen, Christina, Larsen, T., Falk, E. & Bentzon, J. F., 2015, In: Diabetologia. 58, 8, p. 1926-36 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Discovery of plasma proteins associated with ventricular fibrillation during first ST-elevation myocardial infarction via proteomics

    Stampe, N. K., Ottenheijm, Maud Eline, Drici, L., Albrechtsen, Nicolai Jacob Wewer, Nielsen, A. B., Christoffersen, Christina, Warming, P. E., Engstrøm, Thomas, Winkel, B. G., Jabbari, R., Tfelt-Hansen, Jacob & Glinge, C., 2024, In: European Heart Journal: Acute Cardiovascular Care. 13, 3, p. 264–272

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Diurnal gene expression of lipolytic natriuretic peptide receptors in white adipose tissue

    Smith, J., Fahrenkrug, J., Jørgensen, H. L., Christoffersen, Christina & Goetze, J. P., Dec 2015, In: Endocrine Connections. 4, 4, p. 206-214 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Diurnal regulation of sphingolipids in blood

    Brunkhorst, R., Pfeilschifter, W., Rajkovic, N., Pfeffer, M., Fischer, C., Korf, H. W., Christoffersen, Christina, Trautmann, S., Thomas, D., Pfeilschifter, J. & Koch, A., 2019, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1864, 3, p. 304-311

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Effect of apolipoprotein M on high density lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knock-out mice

    Christoffersen, Christina, Jauhiainen, M., Moser, M., Porse, Bo Torben, Ehnholm, C., Boesl, M., Dahlbäck, B. & Nielsen, L. B., 25 Jan 2008, In: The Journal of Biological Chemistry. 283, 4, p. 1839-47 9 p.

    Research output: Contribution to journal › Journal article › Research

  42. Published

    Effect of atrial natriuretic peptide on lipolysis in the mouse heart

    Bartels, Emil Daniel, Bisgaard, Line, Christoffersen, Christina & Nielsen, L. B., 2014, In: Cardiovascular Endocrinology. 3, 3, p. 92-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Effect of insulin on natriuretic peptide gene expression in porcine heart

    Terzic, D., Zois, N. E., Hunter, I., Christoffersen, Christina, Plomgaard, Peter Stendahl, Olsen, Lisbeth Høier, Jørgensen, Stine Ringholm, Pilegaard, Henriette & Goetze, Jens P. , 2020, In: Peptides. 131, 10 p., 170370.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Effect of menopause and exercise training on plasma apolipoprotein M and sphingosine-1-phosphate

    Yafasova, A., djc739, djc739, Egelund, J., Nyberg, M. P., Stallknecht, Bente Merete, Hellsten, Ylva, Nielsen, L. B. & Christoffersen, Christina, 2019, In: Journal of Applied Physiology. 126, 1, p. 214-220 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Effects of a novel selenosugar on primary human vascular cells, mouse aortic rings and atherosclerosis in apoE-/- mice: [Meeting Abstract]

    Zacharias, T., Flouda, K., Jepps, T., Christoffersen, Christina, Pedersen, T., Gammelgaard, Bente, Schiesser, C. & Davies, Michael J., 20 May 2018, In: Free Radical Biology & Medicine. 120, S1, p. S68-S68 P-79.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  46. Published

    Effects of apolipoprotein M in uremic atherosclerosis

    Bosteen, M. H., Madsen Svarrer, E. M., Bisgaard, Line, Martinussen, Torben, Madsen, M., Nielsen, L. B., Christoffersen, Christina & Pedersen, T. X., Oct 2017, In: Atherosclerosis. 265, p. 93-101 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Endothelial and lipoprotein lipases in human and mouse placenta

    Lindegaard, M. L. S., Olivecrona, G., Christoffersen, Christina, Kratky, D., Hannibal, Jens, Petersen, B. L., Zechner, R., Damm, Peter & Nielsen, L. B., 1 Nov 2005, In: Journal of Lipid Research. 46, 11, p. 2339-46 8 p.

    Research output: Contribution to journal › Journal article › Research

  48. Published

    Endothelial and lipoprotein lipases in human and mouse placenta

    Lindegaard, M. L. S., Olivecrona, G., Christoffersen, Christina, Kratky, D., Hannibal, Jens, Petersen, B. L., Zechner, R., Damm, Peter & Nielsen, L. B., Nov 2005, In: Journal of Lipid Research. 46, 11, p. 2339-46 8 p.

    Research output: Contribution to journal › Journal article › Research

  49. Published

    Endothelial-Specific Loss of Sphingosine-1-Phosphate Receptor 1 Increases Vascular Permeability and Exacerbates Bleomycin-induced Pulmonary Fibrosis

    Knipe, R. S., Spinney, J. J., Abe, E. A., Probst, C. K., Franklin, A., Logue, A., Giacona, F., Drummond, M., Griffith, J., Brazee, P. L., Hariri, L. P., Montesi, S. B., Black, K. E., Hla, T., Kuo, A., Cartier, A., Engelbrecht, E., Christoffersen, C., Shea, B. S., Tager, A. M. & 1 others, Medoff, B. D., 2022, In: American Journal of Respiratory Cell and Molecular Biology. 66, 1, p. 38-52 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Endothelium-protective sphingosine-1-phosphate provided by HDL-associated apolipoprotein M

    Christoffersen, Christina, Obinata, H., Kumaraswamy, S. B., Galvani, S., Ahnström, J., Sevvana, M., Egerer-Sieber, C., Muller, Y. A., Hla, T., Nielsen, L. B. & Dahlbäck, B., 2011, In: Proceedings of the National Academy of Sciences USA (PNAS). 108, 23, p. 9613-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 18392597