Thomas Mandrup-Poulsen

Thomas Mandrup-Poulsen

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    1. Published

      The Fas pathway is involved in pancreatic beta cell secretory function.

      Schumann, D. M., Maedler, K., Franklin, I., Konrad, D., Størling, J., Böni-Schnetzler, M., Gjinovci, A., Kurrer, M. O., Gauthier, B. R., Bosco, D., Andres, A., Berney, T., Greter, M., Becher, B., Chervonsky, A. V., Halban, P. A., Mandrup-Poulsen, Thomas, Wollheim, C. B. & Donath, M. Y., 2007, In: Proceedings of the National Academy of Science of the United States of America. 104, 8, p. 2861-6 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      The Faroese, a genetic isolate with a strong founder effect, allows the identification of Type 1 diabetes susceptibility regions

      Nolsoe, R., Roin, J., Deckert, M., Bergholdt, R., Kelly, J., Brorsson, C., Harley, J., Olsen, S., Pociot, Flemming & Mandrup-Poulsen, Thomas, 2008, In: Clinical Immunology. 127, Suppl. S, p. S105-S105

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      The Connexin 43 Regulator Rotigaptide Reduces Cytokine-Induced Cell Death in Human Islets

      Ghiasi, S. M., Hansen, J. B., Christensen, D. P., Tyrberg, B. & Mandrup-Poulsen, Thomas, 2020, In: International Journal of Molecular Sciences (Online). 21, 12, 15 p., 4311.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Targeting innate immune mediators in type 1 and type 2 diabetes

      Donath, M. Y., Dinarello, C. A. & Mandrup-Poulsen, Thomas, 2019, In: Nature Reviews. Immunology. 19, 12, p. 734-746

      Research output: Contribution to journal › Review › Research › peer-review

    5. Published

      TRAF2 mediates JNK and STAT3 activation in response to IL-1β and IFNγ and facilitates apoptotic death of insulin-producing β-cells

      Prause, Michala Cecilie Burstein, Berchtold, L. A., Urizar, A. I., Trauelsen, Mette, Billestrup, Nils, Mandrup-Poulsen, Thomas & Størling, Joachim, 15 Jan 2016, In: Molecular and Cellular Endocrinology. 420, p. 24-36 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: evidence of improved immune regulation

      Ablamunits, V., Henegariu, O., Hansen, J. B., Opare-Addo, L., Preston-Hurlburt, P., Santamaria, P., Mandrup-Poulsen, Thomas & Herold, K. C., 2012, In: Diabetes. 61, 1, p. 145-54 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes

      Larsen, C. M., Faulenbach, M., Vaag, Allan, Ehses, J. A., Donath, M. Y. & Mandrup-Poulsen, Thomas, 2009, In: Diabetes Care. 32, 9, p. 1663-8 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Suppressor of cytokine signalling-3 inhibits Tumor necrosis factor-alpha induced apoptosis and signalling in beta cells

      Bruun, C., Heding, P. E., Rønn, S. G., Frobøse, H., Rhodes, C. J., Mandrup-Poulsen, Thomas & Billestrup, Nils, 2009, In: Molecular and Cellular Endocrinology. 311, 1-2, p. 32-8 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection

      Rønn, S. G., Börjesson, A., Bruun, C., Heding, P. E., Frobøse, H., Mandrup-Poulsen, Thomas, Karlsen, A. E., Rasschaert, J., Sandler, S. & Billestrup, Nils, 2008, In: Diabetologia. 51, 10, p. 1873-1882 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kappaB-regulated proapoptotic pathways

      Karlsen, A. E., Heding, P. E., Frobøse, H., Rønn, S. G., Kruhøffer, M., Orntoft, T. F., Darville, M., Eizirik, D. L., Pociot, Flemming, Nerup, J., Mandrup-Poulsen, Thomas & Billestrup, Nils, 1 Nov 2004, In: Diabetologia. 47, 11, p. 1998-2011 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 923693