Michael J. Davies
Professor
Inflammation, Metabolism and Oxidation
Blegdamsvej 3
2200 København N.
- Published
Exploring oxidative modifications of tyrosine: An update on mechanisms of formation, advances in analysis and biological consequences
Houée-Lévin, C., Bobrowski, K., Horakova, L., Karademir, B., Schöneich, C., Davies, Michael J. & Spickett, C. M., Apr 2015, In: Free Radical Research. 49, 4, p. 347-73 27 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The illness beliefs of people newly diagnosed with type 2 diabetes: results from the DESMOND pilot study
Heller, S., Davies, Michael J., Khunti, K., Skinner, Timothy & James, P., 1 Jan 2005, Diabetologia.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
- Published
Beta-scission of side-chain alkoxyl radicals on peptides and proteins results in the loss of side-chains as aldehydes and ketones
Headlam, H. A. & Davies, Michael J., 1 Jun 2002, In: Free Radical Biology & Medicine. 32, 11, p. 1171-84 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cell-mediated reduction of protein and peptide hydroperoxides to reactive free radicals
Headlam, H. A. & Davies, Michael J., 1 Jan 2003, In: Free Radical Biology & Medicine. 34, 1, p. 44-55 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products
Headlam, H. A. & Davies, Michael J., 2004, In: Free Radical Biology & Medicine. 36, 9, p. 1175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides
Headlam, H. A., Gracanin, M., Rodgers, K. J. & Davies, Michael J., 1 May 2006, In: Free Radical Biology & Medicine. 40, 9, p. 1539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
beta-Scission of C-3 (beta-carbon) alkoxyl radicals on peptides and proteins: a novel pathway which results in the formation of alpha-carbon radicals and the loss of amino acid side chains
Headlam, H. A., Mortimer, A., Easton, C. J. & Davies, Michael J., Nov 2000, In: Chemical Research in Toxicology. 13, 11, p. 1087-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure to peroxynitrite impacts the ability of anastellin to modulate the structure of extracellular matrix
He, Jianfei, Chuang, Christine, Hawkins, Clare Louise, Davies, Michael J. & Hägglund, Per Mårten, 2023, In: Free Radical Biology and Medicine. 206, p. 83-93 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anastellin impacts on the processing of extracellular matrix fibronectin and stimulates release of cytokines from coronary artery smooth muscle cells
He, Jianfei, Steffen, Jonas Hyld, Thulstrup, Peter Waaben, Pedersen, J. N., Sauerland, Max Benjamin, Otzen, D. E., Hawkins, Clare Louise, Gourdon, Pontus Emanuel, Davies, Michael J. & Hägglund, Per Mårten, 2022, In: Scientific Reports. 12, 1, 15 p., 22051.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peroxynitrous acid (ONOOH) modifies the structure of anastellin and influences its capacity to polymerize fibronectin
He, Jianfei, Becares, E. R., Thulstrup, Peter Waaben, Gamon, Luke Francis, Pedersen, J. N., Otzen, D., Gourdon, Pontus Emanuel, Davies, Michael J. & Hägglund, Per Mårten, 2020, In: Redox Biology. 36, 11 p., 101631.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benzoyl peroxide-induced damage to DNA and its components: direct evidence for the generation of base adducts, sugar radicals, and strand breaks
Hazlewood, C. & Davies, Michael J., 1 Aug 1996, In: Archives of Biochemistry and Biophysics. 332, 1, p. 79-91 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins
Hazell, L. J., Davies, Michael J. & Stocker, R., 1999, In: Biochemical Journal. 339 ( Pt 3), p. 489-95 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced damage to DNA, RNA, and polynucleotides: formation of chloramines and nitrogen-centered radicals
Hawkins, Clare Louise & Davies, Michael J., Jan 2002, In: Chemical Research in Toxicology. 15, 1, p. 83-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reaction of protein chloramines with DNA and nucleosides: evidence for the formation of radicals, protein-DNA cross-links and DNA fragmentation
Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael J., 1 Aug 2002, In: Biochemical Journal. 365, Pt 3, p. 605-15 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation
Hawkins, Clare Louise, Pattison, D. I., Stanley, N. R. & Davies, Michael J., 15 Dec 2008, In: Biochemical Journal. 416, 3, p. 441-52 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function
Hawkins, Clare Louise & Davies, Michael J., Oct 2005, In: Chemical Research in Toxicology. 18, 10, p. 1600-10 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of reactive N-bromo species and radical intermediates in hypobromous acid-induced protein oxidation
Hawkins, Clare Louise & Davies, Michael J., 1 Oct 2005, In: Free Radical Biology & Medicine. 39, 7, p. 900-12 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantification of protein modification by oxidants
Hawkins, Clare Louise, Morgan, P. E. & Davies, Michael J., 15 Apr 2009, In: Free Radical Biology & Medicine. 46, 8, p. 965-88 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Superoxide radicals can act synergistically with hypochlorite to induce damage to proteins
Hawkins, Clare Louise, Rees, M. D. & Davies, Michael J., 2 Jan 2002, In: FEBS Letters. 510, 1-2, p. 41-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
The role of aromatic amino acid oxidation, protein unfolding, and aggregation in the hypobromous acid-induced inactivation of trypsin inhibitor and lysozyme
Hawkins, Clare Louise & Davies, Michael J., Nov 2005, In: Chemical Research in Toxicology. 18, 11, p. 1669-77 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Detection and characterisation of radicals in biological materials using EPR methodology
Hawkins, Clare Louise & Davies, Michael J., Feb 2014, In: B B A - Reviews on Cancer. 1840, 2, p. 708-21 14 p.Research output: Contribution to journal › Review › Research › peer-review
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Detection, identification, and quantification of oxidative protein modifications
Hawkins, Clare Louise & Davies, Michael J., 2019, In: Journal of Biological Chemistry. 294, 51, p. 19683-19708Research output: Contribution to journal › Review › Research › peer-review
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Role of myeloperoxidase and oxidant formation in the extracellular environment in inflammation-induced tissue damage
Hawkins, Clare Louise & Davies, Michael J., 2021, In: Free Radical Biology and Medicine. 172, p. 633-651Research output: Contribution to journal › Review › Research › peer-review
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Degradation of hyaluronic acid, poly- and monosaccharides, and model compounds by hypochlorite: evidence for radical intermediates and fragmentation
Hawkins, C. L. & Davies, Michael J., Jun 1998, In: Free Radical Biology & Medicine. 24, 9, p. 1396-410 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced damage to nucleosides: formation of chloramines and nitrogen-centered radicals
Hawkins, C. L. & Davies, Michael J., Aug 2001, In: Chemical Research in Toxicology. 14, 8, p. 1071-81 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Generation and propagation of radical reactions on proteins
Hawkins, C. L. & Davies, Michael J., 2 Apr 2001, In: B B A - Reviews on Cancer. 1504, 2-3, p. 196-219 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hypochlorite-induced damage to red blood cells: evidence for the formation of nitrogen-centred radicals
Hawkins, C. L. & Davies, Michael J., 2000, In: Redox Report (Online). 5, 1, p. 57-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxidative damage to collagen and related substrates by metal ion/hydrogen peroxide systems: random attack or site-specific damage?
Hawkins, C. L. & Davies, Michael J., 27 Feb 1997, In: B B A - Reviews on Cancer. 1360, 1, p. 84-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation
Hawkins, C. L. & Davies, Michael J., 1 Jun 1999, In: Biochemical Journal. 340 ( Pt 2), p. 539-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced oxidation of amino acids, peptides and proteins
Hawkins, C. L., Pattison, D. I. & Davies, Michael J., Dec 2003, In: Amino Acids. 25, 3-4, p. 259-74 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite- and hypobromite-mediated radical formation and its role in cell lysis
Hawkins, C. L., Brown, B. E. & Davies, Michael J., 15 Nov 2001, In: Archives of Biochemistry and Biophysics. 395, 2, p. 137-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypochlorite-induced damage to proteins: formation of nitrogen-centred radicals from lysine residues and their role in protein fragmentation
Hawkins, C. L. & Davies, Michael J., 15 Jun 1998, In: Biochemical Journal. 332 ( Pt 3), p. 617-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A biotin enrichment strategy identifies novel carbonylated amino acids in proteins from human plasma
Havelund, J. F., Wojdyla, K. I., Davies, Michael J., Jensen, O. N., Møller, I. M. & Rogowska-Wrzesinska, A., 6 Mar 2017, In: Journal of Proteomics. 156, p. 40-51 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides
Hampton, M. B., Morgan, P. E. & Davies, Michael J., 11 Sep 2002, In: FEBS Letters. 527, 1-3, p. 289-92 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral pre-treatment with thiocyanate (SCN-) protects against myocardial ischaemia-reperfusion injury in rats
Hall, L., Guo, C., Tandy, S., Broadhouse, K., Dona, A. C., Malle, E., Bartels, Emil Daniel, Christoffersen, Christina, Grieve, S. M., Figtree, G., Hawkins, Clare Louise & Davies, Michael J., 2021, In: Scientific Reports. 11, 1, 18 p., 12712.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification and characterization of protein cross-links induced by oxidative reactions
Hägglund, Per Mårten, Mariotti, M. & Davies, Michael J., 2018, In: Expert Review of Proteomics. 15, 8, p. 665-681Research output: Contribution to journal › Review › Research › peer-review
- Published
Radical chemistry of epigallocatechin gallate and its relevance to protein damage
Hagerman, A. E., Dean, R. T. & Davies, Michael J., 1 Jun 2003, In: Nitric Oxide: Biology and Chemistry. 414, 1, p. 115-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl)
Hadfield, K. A., Pattison, D. I., Brown, B. E., Hou, L., Rye, K., Davies, Michael J. & Hawkins, Clare Louise, 15 Jan 2013, In: Biochemical Journal. 449, 2, p. 531-42 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages
Guo, C., Sileikaite, I., Davies, Michael J. & Hawkins, Clare Louise, 2020, In: Antioxidants. 9, 12, 14 p., 1255.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of thiocyanate in the modulation of myeloperoxidase-derived oxidant induced damage to macrophages
Guo, C., Davies, Michael J. & Hawkins, Clare Louise, Sep 2020, In: Redox Biology. 36, 14 p., 101666.Research output: Contribution to journal › Journal article › Research › peer-review
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Screening for type 2 diabetes in a multiethnic setting using known risk factors to identify those at high risk: A cross-sectional study
Gray, L. J., Tringham, J. R., Davies, Michael J., Webb, D. R., Jarvis, J., Skinner, Timothy, Farooqi, A. M. & Khunti, K., 1 Dec 2010, In: Vascular Health and Risk Management. 6, 1, p. 837-842 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings
Graham, G. G., Davies, Michael J., Day, R. O., Mohamudally, A. & Scott, K. F., Jun 2013, In: Inflammopharmacology. 21, 3, p. 201-32 32 p.Research output: Contribution to journal › Journal article › Research › peer-review
Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome
Gracanin, M., Lam, M. A., Morgan, P. E., Rodgers, K. J., Hawkins, Clare Louise & Davies, Michael J., 15 Jan 2011, In: Free Radical Biology & Medicine. 50, 2, p. 389-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products
Gracanin, M. & Davies, Michael J., 15 May 2007, In: Free Radical Biology & Medicine. 42, 10, p. 1543-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products
Gracanin, M., Hawkins, Clare Louise, Pattison, D. I. & Davies, Michael J., 1 Jul 2009, In: Free Radical Biology & Medicine. 47, 1, p. 92-102 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidation of the active site cysteine residue of glyceraldehyde-3-phosphate dehydrogenase to the hyper-oxidized sulfonic acid form is favored under crowded conditions
Glover, M. R., Davies, Michael J. & Fuentes Lemus, Eduardo, 2024, In: Free Radical Biology and Medicine. 212, p. 1-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: Cost effectiveness analysis
Gillett, M., Dallosso, H. M., Dixon, S., Brennan, A., Carey, M. E., Campbell, M. J., Heller, S., Khunti, K., Skinner, Timothy & Davies, Michael J., 26 Aug 2010, In: BMJ (Online). 341, 7770, c4093.Research output: Contribution to journal › Journal article › Research › peer-review
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Whey proteins: targets of oxidation, or mediators of redox protection
Giblin, L., Yalcin, A. S., Bicim, G., Kramer, A. C., Chen, Z., Callanan, M. J., Arranz, E. & Davies, Michael J., 2019, In: Free Radical Research. 53, S1, p. 1136–1152 17 p.Research output: Contribution to journal › Review › Research › peer-review
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Endothelial nitric oxide synthase plays a protective role in endothelial cells and cardiomyocytes against myocardial infarction
Gentile, C., Kesteven, S., Wu, J., Davies, Michael J., Bursill, C., Feneley, M. & Figtree, G., 2020, In: Journal of Molecular and Cellular Cardiology. 140, p. 31-31Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
A Novel Method for Isolating and Culturing Human Cardiomyocytes from Cryopreserved Tissues
Gentile, C., Kuehn, B., Davies, Michael J. & dos Remedios, C. G., 2014, In: Biophysical Journal.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 38036205
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Protein oxidation and peroxidation
Research output: Contribution to journal › Review › Research › peer-review
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255
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Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
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239
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment
Research output: Contribution to journal › Journal article › Research › peer-review
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