Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Glucagon Resistance at the Level of Amino Acid Turnover in Obese Subjects With Hepatic Steatosis

    Suppli, M. P., Bagger, J. I., Lund, A., Demant, M., van Hall, Gerrit, Strandberg, C., Kønig, M. J., Rigbolt, K., Langhoff, J. L., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes. 69, 6, p. 1090-1099 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Reduced GLP-1 Secretion at 30 Minutes After a 75g Oral Glucose Load is Observed in Gestational Diabetes Mellitus: A Prospective Cohort Study

    Sukumar, N., Bagias, C., Goljan, I., Weldeselassie, Y., Gharanei, S., Tan, B. K., Holst, Jens Juul & Saravanan, P., 1 Dec 2018, In: Diabetes. 67, 12, p. 2650-2656

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Effect of liraglutide on body weight and microvascular function in non-diabetic overweight women with coronary microvascular dysfunction

    Suhrs, H. E., Raft, K. F., Bové, K., Madsbad, Sten, Holst, Jens Juul, Zander, M. & Prescott, Eva, 2 Jan 2019, In: International Journal of Cardiology. 283, p. 28-34

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Stimulation of intestinal growth and function with DPP-IV inhibition in a mouse short bowel syndrome model

    Sueyoshi, R., Ignatoski, K. M. W., Okawada, M., Hartmann, Bolette, Holst, Jens Juul & Teitelbaum, D. H., 26 Jun 2014, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 307, 4, p. G410-19 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    A glucose-insulin-glucagon coupled model of the isoglycemic intravenous glucose infusion experiment

    Subramanian, V., Bagger, J. I., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Frontiers in Physiology. 13, 20 p., 911616.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    An Extended Minimal Model of OGTT: estimation of α- and β-cell dysfunction, insulin resistance, and the incretin effect

    Subramanian, V., Bagger, J. I., Harihar, V., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 326, 2, p. E182-E205

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Hepatic autoregulation: response of glucose production and gluconeogenesis to increased glycogenolysis

    Stæhr, P. A., Hother-Nielsen, O., Beck-Nielsen, H., Roden, M., Stingl, H., Holst, Jens Juul, Jones, P. K., Chandramouli, V. & Landau, B. R., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 5, p. E1265-E1269

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs

    Stoll, B., Price, P. T., Reeds, P. J., Chang, X., Henry, J. F., van Goudoever, J. B., Holst, Jens Juul & Burrin, D. G., 3 Jan 2006, In: Journal of Parenteral and Enteral Nutrition. 30, 1, p. 32-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Continuous parenteral and enteral nutrition induces metabolic dysfunction in neonatal pigs

    Stoll, B., Puiman, P. J., Cui, L., Chang, X., Benight, N. M., Bauchart-Thevret, C., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Sep 2012, In: Journal of Parenteral and Enteral Nutrition. 36, 5, p. 538-50 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs

    Stoll, B., Price, P. T., Reeds, P. J., Chang, X., Henry, J. F., Goudoever, J. B. V., Holst, Jens Juul & Burrin, D. G., 2006, In: Journal of Parenteral and Enteral Nutrition. 30, 1, p. 32-39 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Altered Glucagon and GLP-1 Responses to Oral Glucose in Children and Adolescents With Obesity and Insulin Resistance

    Stinson, Sara, Fernández de Retana Alzola, I., Hovendal, Emilie Damgaard Brünner, Lund, Morten Asp Vonsild, Fonvig, Cilius Esmann, Holm, Louise Aas, Jonsson, Anna Elisabet, Frithioff-Bøjsøe, C., Christiansen, Michael, Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, T. I. A., Holst, Jens Juul, Hartmann, Bolette, Holm, Jens-Christian & Hansen, Torben, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 6, p. 1590-1600 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Hyperglucagonemia in pediatric adiposity associates with cardiometabolic risk factors but not hyperglycemia

    Stinson, Sara, Jonsson, Anna Elisabet, Alzola, I. F. D. R., Lund, Morten Asp Vonsild, Frithioff-Bøjsøe, C., Holm, L. A., Fonvig, Cilius Esmann, Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, Thorkild I.A., Holst, Jens Juul, Christiansen, M., Holm, Jens-Christian, Hartmann, Bolette & Hansen, Torben, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 6, p. 1569–1576

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Fasting plasma GLP-1 associates with overweight/obesity and cardiometabolic risk factors in children and adolescents

    Stinson, Sara, Jonsson, Anna Elisabet, Lund, M. A. V., Frithioff-Bøjsøe, C., Holm, L. A., Pedersen, Oluf Borbye, Ängquist, Lars, Sørensen, Thorkild I.A., Holst, Jens Juul, Christiansen, M., Holm, Jens-Christian, Hartmann, Bolette & Hansen, Torben, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 6, p. 1718-1727

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Effects of short-term therapy with glibenclamide and repaglinide on incretin hormones and oxidative damage associated with postprandial hyperglycaemia in people with type 2 diabetes mellitus

    Stephens, J. W., Bodvarsdottir, T. B., Wareham, K., Prior, S. L., Bracken, R. M., Lowe, G. D., Rumley, A., Dunseath, G., Luzio, S., Deacon, Carolyn F., Holst, Jens Juul & Bain, S. C., Nov 2011, In: Diabetes Research and Clinical Practice. 94, 2, p. 199-206 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Effects of endogenous GIP in patients with type 2 diabetes

    Stensen, S., Gasbjerg, Lærke Smidt, Krogh, L. L., Skov-Jeppesen, Kirsa, wbf943, wbf943, Jensen, M. H., Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 33-45

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Endogenous Glucose-Dependent Insulinotropic Polypeptide Contributes to Sitagliptin-Mediated Improvement in Beta Cell Function in Patients with Type 2 Diabetes

    Stensen, S., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Diabetes. 71, 10, p. 2209-2221

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Acute concomitant GIP receptor antagonism during GLP-1 receptor agonism does not affect appetite, resting energy expenditure or food intake in patients with type 2 diabetes and overweight/obesity

    Stensen, S., Krogh, L. L., wbf943, wbf943, Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 9, p. 1882-1887

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Glucose-dependent insulinotropic polypeptide (GIP) contributes to sitagliptin-mediated improvement of beta cell function in patients with type 2 diabetes

    Stensen, S., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 95-95 179.

    Research output: Contribution to journal › Conference abstract in journal › Research

  19. Published

    Endogenous glucose-dependent insulinotropic polypeptide exerts diverging and tissue specific in obese patients with type 2 diabetes

    Stensen, S., Gasbjerg, Lærke Smidt, Krogh, L. L., wbf943, wbf943, Skov-Jeppesen, Kirsa, Jensen, M. H., Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, M. B. & Knop, Filip Krag, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S270-S271 2 p., 560.

    Research output: Contribution to journal › Conference abstract in journal › Research

  20. Published

    Gastric Emptying and Distal Gastrectomy Independently Enhance Postprandial Glucagon-Like Peptide-1 Release After a Mixed Meal and Improve Glycemic Control in Subjects Having Undergone Pancreaticoduodenectomy

    Steiner, E., Breuer, R., Kazianka, L., Wewalka, M., Stimpfl, T., Reiter, B., Holst, Jens Juul & Miholic, J., 2019, In: Pancreas. 48, 7, p. 953-957

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    WITHDRAWN: Glucagon processing

    Steiner, D. F., Albrechtsen, Nicolai Jacob Wewer, Rehfeld, Jens Frederik & Holst, Jens Juul, 2016, The Curated Reference Collection in Neuroscience and Biobehavioral Psychology. Elsevier

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  22. Published

    Preserved glucose response to low-dose glucagon after exercise in insulin-pump-treated individuals with type 1 diabetes: a randomised crossover study

    Steineck, I. I. K., Ranjan, A., Schmidt, S., Clausen, T. R., Holst, Jens Juul & Nørgaard, Kirsten, 2019, In: Diabetologia. 62, 4, p. 582-592

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Preserved glucose response to low-dose glucagon after exercise in insulin pump-treated individuals with type 1 diabetes: a randomised crossover study

    Steineck, I. I. K., Ranjan, A., Schmidt, S., Clausen, T. R., Holst, Jens Juul & Norgaard, K., 2018, In: Diabetologia. 61, S1, p. S75-S76 2 p., 146.

    Research output: Contribution to journal › Conference abstract in journal › Research

  24. Published

    MODERATE EXERCISE DOES NOT IMPAIR THE EFFECT OF GLUCAGON IN INSULIN PUMP TREATED INDIVIDUALS WITH TYPE 1 DIABETES: A RANDOMIZED CROSSOVER STUDY: [Meeting Abstract}

    Steineck, I., Ranjan, A., Schmidt, S., Holst, Jens Juul & Norgaard, K., 2018, In: Diabetes Technology & Therapeutics. 20, p. A35-A35 072.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  25. Published

    Acute disruption of glucagon secretion or action does not improve glucose tolerance in an insulin-deficient mouse model of diabetes

    Steenberg, V. R., Jensen, S. M., Pedersen, Jens, Madsen, A. N., Windeløv, Johanne Agerlin, Holst, Birgitte, Quistorff, B., Poulsen, Steen Seier & Holst, Jens Juul, 2016, In: Diabetologia. 59, 2, p. 363-370 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Glucose Tolerance Tests and Osteocalcin Responses in Healthy People

    Starup-Linde, J., Westberg-Rasmussen, S., Lykkeboe, S., Handberg, A., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K., Vestergaard, P. & Gregersen, S., 2018, In: Frontiers in Endocrinology. 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis.

    Staehr, P., Hother-Nielsen, O., Landau, B. R., Chandramouli, V., Holst, Jens Juul & Beck-Nielsen, H., 2003, In: Diabetes. 52, 2, p. 260-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Does overnight normalization of plasma glucose by insulin infusion affect assessment of glucose metabolism in type 2 diabetes

    Staehr, P., Højlund, K., Hother-Nielsen, O., Holst, Jens Juul & Beck-Nielsen, H., 2003, In: Diabetic Medicine. 20, p. 816-822

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Assesment of hepatic insulin action in obese type 2 diabetic patients

    Staehr, P., Hother-Nielsen, O., Levin, K. & Holst, Jens Juul, 2001, In: Diabetes. 50, p. 1363-1370

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release

    wbf943, wbf943, Gabe, M. N., Gasbjerg, Lærke Smidt, Christiansen, Charlotte Bayer, Svendsen, B., Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, 2017, In: Biochemical Pharmacology. 131, p. 78-88

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Species-specific action of (Pro3)GIP - an efficacious agonist on human GIP receptor, but partial agonist and competitive antagonist on rat and mouse GIP receptors

    wbf943, wbf943, Gasbjerg, Lærke Smidt, Svendsen, B., Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Jan 2016, In: British Journal of Pharmacology. 173, 1, p. 27-38 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Protein dose-response effect on glp-1, pyy and appetite in male subjects

    Sparre, A. B., Sørensen, M. Q., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2011, In: Obesity Reviews. 12, suppl. 1, p. 59 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  33. Published

    Contribution of gastroenteropancreatic appetite hormones to protein-induced satiety

    Sparre, A. B., Ritz, C., Sørensen, M. Q., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2013, In: American Journal of Clinical Nutrition. 97, 5, p. 980-989 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Renoprotective effects of dulaglutide in patients with T2DM and CKD

    Sorensen, Charlotte Mehlin & Holst, Jens Juul, 2018, In: Nature Reviews. Nephrology. 14, 11, p. 659-660

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  35. Published

    Postprandial gallbladder emptying in patients with type 2 diabetes: potential implications for bile-induced secretion of glucagon-like peptide 1

    Sonne, David Peick, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Oct 2014, In: European Journal of Endocrinology. 171, 4, p. 407-419 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    On the role of gallbladder emptying and incretin hormones for nutrient-mediated TSH suppression in patients with type 2 diabetes

    Sonne, David Peick, Lund, Asger Bach, Faber, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2014, In: Endocrine Connections. 3, 4, p. 193-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Postprandial gut hormone responses and glucose metabolism in cholecystectomized patients

    Sonne, D. P., Hare, K. J., Martens, P., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 15 Feb 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 4, p. G413-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Examining the effects of hyperglycemia on pancreatic endocrine function in humans: evidence for in vivo glucotoxicity

    Solomon, T. P. J., Knudsen, S. H., Karstoft, K., Winding, K., Holst, Jens Juul & Pedersen, Bente Klarlund, Dec 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 12, p. 4682-91 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Endogenous glucagon-like peptide (GLP)-1 as alternative for GLP-1 receptor agonists: Could this work and how?

    Smits, Mark & Holst, Jens Juul, 2023, In: Diabetes/Metabolism Research and Reviews. 39, 8, 17 p., e3699.

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    Indole-3-carboxyaldehyde does not reverse the intestinal effects of fiber-free diet in mice

    Smits, Mark, Dreyer, S. I. L., Dal, Jenna Elizabeth Hunt, Drzazga, Anna Katarzyna, Modvig, Ida Marie, Holst, Jens Juul & Kissow, Hannelouise, 2024, In: Frontiers in Endocrinology. 15, 10 p., 1362711.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    In Vivo Inhibition of Dipeptidyl Peptidase 4 Allows Measurement of GLP-1 Secretion in Mice

    Smits, Mark, Galsgaard, Katrine Douglas, Jepsen, Sara Lind, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette & Holst, Jens Juul, 2024, In: Diabetes. 73, 5, p. 671-681

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Comparative analysis of oral and intraperitoneal glucose tolerance tests in mice

    Small, Lewin Barkla, Ehrlich, Amy M, Iversen, Jo Frøkjær, Ashcroft, Stephen Paul, Trošt, K., Moritz, Thomas, Hartmann, Bolette, Holst, Jens Juul, Treebak, Jonas Thue, Zierath, Juleen R & Barrès, Romain, 2022, In: Molecular Metabolism. 57, 8 p., 101440.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The L-alpha-amino acid receptor GPRC6A is expressed in the islets of Langerhans but is not involved in L-arginine-induced insulin release

    Smajilovic, S., Clemmensen, Christoffer, Johansen, L. D., Wellendorph, Petrine, Holst, Jens Juul, Thams, P. G., Ogo, E. & Bräuner, Hans, 2013, In: Amino Acids. 44, 2, p. 383-390 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acids concentration in obese males

    Sloth, B., Davidsen, L., Holst, Jens Juul, Flint, A. & Astrup, A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 2, p. E604-E609

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Effects of low vs. high glycemic index diets on appetite and energy expenditure

    Sloth, B., Krog-Mikkelsen, I., Dimitrov, D., Holst, Jens Juul, Flint, A., Tetens, Inge , Björck, I., Elmstahl, H., Astrup, A. & Raben, A., 2004. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research

  46. Published

    The effect of a high-MUFA, low-glycaemic index diet and a low-fat diet on appetite and glucose metabolism during a 6-month weight maintenance period

    Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: British Journal of Nutrition. 101, 12, p. 1846-1858 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Appetitregulering: et komplekst system

    Sloth, B. & Holst, Jens Juul, 2008, In: Perspektiv : tidsskrift om ernæring. 1, p. 4-8 5 p.

    Research output: Contribution to journal › Journal article › Communication

  48. Published

    The effect of a high monounsaturated fatty acid, low glycemic index diet and a low fat diet on satiety, appetite regulatory hormones and glucose metabolism during a 6 mo weight maintenance period

    Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: International Journal of Obesity. 32, Suppl. 1, p. S204 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  49. Published

    Effects of PYY1-36 and PYY3-36 on appetite, energy intake, energy expenditure, glucose and fat metabolism in obese and lean subjects.

    Sloth, B., Holst, Jens Juul, Flint, A., Gregersen, N. T. & Astrup, A., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 4, p. E1062-E1068 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Appetitregulering: et komplekst system

    Sloth, B. & Holst, Jens Juul, 2008, In: Perspektiv. 1, 8

    Research output: Contribution to journal › Journal article › Research › peer-review

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