Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo.

    Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2003, In: Advances in Experimental Medicine and Biology. 524, p. 303-12 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 309, 5, p. R544-51 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendahl, C., Vilsbøll, Tina, Knop, Filip Krag & Holst, Jens Juul, 18 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, p. G1117-G1127 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Neutral Endopeptidase 24.11 and dipeptidyl peptidase IV are both physiological mediators of the degradation of glucagon-like peptide-1 in the anaesthetized pig

    Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2005, In: Diabetologia. 48, p. 1882-1890

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig

    Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., Sep 2005, In: Diabetologia. 48, 9, p. 1882-90 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Effects of a meal rich in medium-chain saturated fat on postprandial lipemia in relatives of type 2 diabetics

    Pietraszek, A., Hermansen, K., Pedersen, S. B., Langdahl, B. L., Holst, Jens Juul & Gregersen, S., 2013, In: Nutrition. 29, 7-8, p. 1000-1006 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Acute effects of monounsaturated fat on postprandial lipemia and gene expression in first-degree relatives of subjects with type 2 diabetes

    Pietraszek, A., Gregersen, S., Pedersen, S. B., Holst, Jens Juul & Hermansen, K., 14 May 2014, In: European Journal of Clinical Nutrition. 68, p. 1022-28 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease.

    Piche, T., des Varannes, S. B., Sacher-Huvelin, S., Holst, Jens Juul, Cuber, J. C. & Galmiche, J. P., 2003, In: Gastroenterology. 124, 4, p. 894-902 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development

    Petersen, Y. M., Hartmann, Bolette, Holst, Jens Juul, Le Huerou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, Jun 2003, In: Journal of Nutrition. 133, 6, p. 1781-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Glucagon-like peptide 2 stimulates small-intestine growth and maturation in the pig fetus and neonate

    Petersen, Y. M., Burrin, D. G., Schmidt, M., Elnif, J., Hartmann, B., Holst, Jens Juul & Sangild, Per Torp, 2001, Ikke angivet. Lindberg, J. E., Ogle & B. (eds.). CABI Publishing, p. 23-25 3 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

  11. Published

    Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development

    Petersen, Y. M., Hartmann, B., Holst, Jens Juul, Le Huërou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, 2003, In: Journal of Nutrition. 133, 6, p. 1781-1786 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Perinatal gut growth is not regulated by glucagon-like peptide 2

    Petersen, Y. M., Holst, Jens Juul, Hartmann, B. & Sangild, Per Torp, 2001, Journal of the Society for Gynecological Investigation. 8 ed. p. 172A 1 p.

    Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research

  13. Published

    Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine

    Petersen, N., Frimurer, Thomas Michael, Pedersen, M. T., Egerod, Kristoffer Lihme, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Grapin-Botton, A., Jensen, Kim Bak & Schwartz, Thue W., 2018, In: Gastroenterology. 155, 4, p. 1164-1176 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Hemodynamic Effects of Glucagon: A Literature Review

    Petersen, K. M., Bogevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 1804-1812

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Response to Letter to the Editor: "Hemodynamic Effects of Glucagon: A Literature Review"

    Petersen, K. M., Bøgevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480-4481 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  16. Published

    High-Dose Glucagon Has Hemodynamic Effects Regardless of Cardiac Beta-Adrenoceptor Blockade: A Randomized Clinical Trial

    Petersen, K. M., Bøgevig, S., Riis, T., Andersson, N. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Journal of the American Heart Association. 9, 21, 27 p., e016828.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Cardiovascular effects of high-dose glucagon: a randomised clinical trial

    Petersen, K. M., Bogevig, S., Riis, T., Andersson, N. A. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S231

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  18. Published

    Early growth and postprandial appetite regulatory hormone responses

    Perälä, M., Kajantie, E., Valsta, L. M., Holst, Jens Juul, Leiviskä, J. & Eriksson, J. G., 19 Apr 2013, In: British Journal of Nutrition. 110, 09, p. 1-10 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    GLP-2 administration results in increased proliferation but paradoxically an adverse outcome in a juvenile piglet model of short bowel syndrome

    Pereira-Fantini, P. M., Nagy, E. S., Thomas, S. L., Taylor, R. G., Sourial, M., Paris, M. C. J., Holst, Jens Juul, Fuller, P. J. & Bines, J. E., Jan 2008, In: Journal of Pediatric Gastroenterology and Nutrition. 46, 1, p. 20-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    GLP-2 administration results in increased proliferation but paradoxically an adverse outcome in a juvenile piglet model of short bowel syndrome

    Pereira-Fantini, P. M., Nagy, T. S., Thomas, S. L., Taylor, R. G., Sourial, M., Paris, M. C. J., Holst, J. J., Fuller, P. J., Bines, J. E. & Holst, Jens Juul, 2008, In: Journal of Pediatric Gastroenterology and Nutrition. 46, 1, p. 20-28 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Different Malabsorptive Obesity Surgery Interventions Result in Distinct Postprandial Amino Acid Metabolomic Signatures

    Pereira, S. S., Jarak, I., Carvalho, R. A., Oliveira, P. F., Alves, M. G., Guimaraes, M., Almeida, R., Pereira, A. M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2020, In: Obesity Surgery. 30, p. 4019-4028

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Biliopancreatic diversion with duodenal switch (BPD-DS) and single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) result in distinct post-prandial hormone profiles

    Pereira, S. S., Guimarães, M., Almeida, R., Pereira, A. M., Lobato, C. B., Hartmann, Bolette, Hilsted, Linda, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2019, In: International Journal of Obesity. 43, p. 2518-2527

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Angiotensin-converting enzyme activity and cognitive impairment during hypoglycaemia in healthy humans

    Pedersen-Bjergaard, Ulrik, Thomsen, Carsten Eckhart, Høgenhaven, H., Smed, A., Kjaer, T. W., Holst, Jens Juul, Dela, Flemming, Hilsted, Linda, Frandsen, E., Pramming, S. & Thorsteinsson, B., 2008, In: Journal of the Renin-Angiotensin-Aldosterone System. 9, 1, p. 37-48 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects

    Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The effect of dietary fish oil in addition to lifestyle counselling on lipid oxidation and body composition in slightly overweight teenage boys

    Pedersen, M. H., Mølgaard, Christian, Hellgren, L., Matthiessen, J., Holst, Jens Juul & Lauritzen, Lotte, 2011, In: Journal of Nutrition and Metabolism. 2011, 348368, 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol

    Pedersen, L. R., Olsen, R. H., Frederiksen, M., Astrup, A., Chabanova, E., Hasbak, P., Holst, Jens Juul, Kjær, Andreas, Newman, J. W., Walzem, R., Wisløff, U., Sajadieh, Ahmad, Haugaard, Steen Bendix & Prescott, Eva, 2013, In: B M C Cardiovascular Disorders. 13, 1, 8 p., 106.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Standard procedures for blood withdrawal in conscious male rats induce stress and profoundly affect glucose tolerance and secretion of glucoregulatory hormones

    Pedersen, K., Andersen, H., Fledelius, C., Holst, Jens Juul, Hjuler, S. T. & Kuhre, Rune Ehrenreich, 2023, In: Molecular Metabolism. 69, 101689.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Nonalcoholic Fatty Liver Disease Impairs the Liver-Alpha Cell Axis Independent of Hepatic Inflammation and Fibrosis

    Pedersen, J. S., Rygg, M. O., Kristiansen, V. B., Olsen, B. H., Serizawa, R. R., Holst, Jens Juul, Madsbad, Sten, Gluud, Lise Lotte, Bendtsen, Flemming & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Hepatology Communications. 4, 11, p. 1610-1623 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine

    Pedersen, Jens, B. Pedersen, N., Brix, S. W., Grunddal, Kaare Villum, Rosenkilde, Mette, Hartmann, Bolette, Ørskov, Cathrine, Poulsen, Steen Seier & Holst, Jens Juul, May 2015, In: Peptides. 67, p. 20-28 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Glucagon like-peptide 1 receptor and the liver

    Pedersen, Jens & Holst, Jens Juul, 2011, In: Liver international : official journal of the International Association for the Study of the Liver. 31, 9, p. 1243-5 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells

    Pedersen, J., Ugleholdt, Randi Kjærsgaard, Jørgensen, S. M., Windeløv, Johanne Agerlin, Grunddal, Kaare Villum, Schwartz, Thue W., Füchtbauer, E., Poulsen, Steen Seier, Holst, Peter Johannes & Holst, Jens Juul, 1 Jan 2013, In: American Journal of Physiology: Endocrinology and Metabolism. 304, 1, p. E60-73 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations

    Pearson, E. R., Flechtner, I., Njølstad, P. R., Malecki, M. T., Flanagan, S. E., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J., Holst, Jens Juul, Clark, P. M., Ellard, S., Søvik, O., Polak, M., Hattersley, A. T. & Neonatal Diabetes International Collaborative Group, N. D. I. C. G., 3 Aug 2006, In: New England Journal of Medicine. 355, 5, p. 467-77 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations

    Pearson, E. R., Flechtner, I., Njolstad, P. R., Malecki, M. T., Flanagan, S. E., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J., Holst, Jens Juul, Clark, P. M., Ellard, S., Sovik, O., Polak, M. & Hattersley, A. T., 2006, In: New England Journal of Medicine. 355, 5, p. 467-477 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The successful transfer of insulin treated patients with diabetes due to Kir6.2 (KCNJ11) mutations to oral sulfonylureas

    Pearson, E. R., Flechtner, I., Njølståd, P. R., Malecki, M. T., Flanagan, S., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J. J., Holst, Jens Juul, Clark, P. M., Ellard, S. E., Sovik, O., Polak, M. & Hattersley, A. T., 2006, In: N. Engl. J. Med.. 355, p. 467-477

    Research output: Contribution to journal › Journal article › Research

  35. Published

    Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism

    Patti, M., Houten, S. M., Bianco, A. C., Bernier, R., Larsen, P. R., Holst, Jens Juul, Badman, M. K., Maratos-Flier, E., Mun, E. C., Pihlajamaki, J., Auwerx, J. & Goldfine, A. B., 2009, In: Obesity. 17, 9, p. 1671-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Severe hypoglycemia post-gastric bypass requiring partial pancreatectomy: Evidence for inappropriate insulin secretion and pancreatic islet cell hyperplasia

    Patti, M. E., Mun, E. C., Holst, Jens Juul, Hanto, D. W., Goldsmith, J., Arky, R., Nose, V., Bonner-Weir, S. & Goldfine, A. B., 2005, In: Diabetologia. 48, p. 2236-2240

    Research output: Contribution to journal › Journal article › Research

  37. Published

    Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia

    Patti, M. E., McMahon, G., Mun, E. C., Bitton, A., Holst, Jens Juul, Goldsmith, J., Hanto, D. W., Callery, M., Arky, R., Nose, V., Bonner-Weir, S. & Goldfine, A. B., Nov 2005, In: Diabetologia. 48, 11, p. 2236-40 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Gut hormone release after gastric bypass depends on the length of the biliopancreatic limb

    Patrício, B. G., Morais, T., Guimarães, M., Veedfald, Simon, Hartmann, Bolette, Hilsted, Linda, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 1 May 2019, In: International Journal of Obesity. 43, 5, p. 1009-1018

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens

    Paris, M. C., Fuller, P. J., Carstensen, Bendix, Nagy, E., Taylor, R. G., Sourial, M., Holst, Jens Juul, Hartmann, Bolette & Binesm, J. E., Oct 2004, In: Digestive Diseases and Sciences. 49, 10, p. 1688-95 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens

    Paris, M. C. J., Fuller, P. J., Taylor, R. G., Nagy, E., Sourial, M., Catto-Smith, T., Hartmann, B., Holst, Jens Juul & Bines, J. E., 2004, In: Dig. Dis. Sci.. 49, p. 1688-1695

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    New therapies for obesity

    Papamargaritis, D., le Roux, C. W., Holst, Jens Juul & Davies, M. J., 2023, In: Cardiovascular Research. 119, 18, p. 2825–2842

    Research output: Contribution to journal › Review › Research › peer-review

  42. Published

    The melanocortin-4 receptor is expressed in enteroendocrine L cells and regulates the release of peptide YY and glucagon-like peptide 1 in vivo

    Panaro, B. L., Tough, I. R., Engelstoft, M. S., Matthews, R. T., Digby, G. J., Møller, C. L., Svendsen, B., Gribble, F., Reimann, F., Holst, Jens Juul, Holst, Birgitte, Schwartz, Thue W., Cox, H. M. & Cone, R. D., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 1018-29 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The release of gastric inhibitory peptide, glucagon-like peptide-1, and insulin after oral glucose test in colectomized subjects.

    Palnæs Hansen, C., Andreassen, J. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 473-477

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Glucose absorption and the release of insulin, gastric inhibitory polypeptide, and glucagon-like peptide-1 in patients after total colectomy.

    Palnæs Hansen, C., Andreassen, J. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 473-477

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota

    Palleja, A., Kashani, A., Allin, K. H., Nielsen, T., Zhang, C., Li, Y., Brach, Thorsten, Liang, S., Feng, Q., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Burgdorf, Kristoffer Sølvsten, Holst, Jens Juul, Madsbad, Sten, Wang, J., Pedersen, Oluf Borbye, Hansen, Torben & Arumugam, Mani, 2016, In: Genome Medicine. 8, 13 p., 67.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    The Relationship between Glucagon-Like Peptide 2 and Feeding Intolerance in Preterm Infants.

    Ozer, E. A., Holst, Jens Juul, Duman, N., Kumral, A. & Ozkan, H., 2008, In: Journal of Tropical Pediatrics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion

    Ouaghlidi, A. E., Rehring, E., Holst, Jens Juul, Schweizer, A., Foley, J., Holmes, D. & Nauck, M. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 11, p. 4165-4171 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Postprandial levels of GLP-1, GIP and glucagon after 2 years of weight loss with a Paleolithic diet: a randomised controlled trial in healthy obese women

    Otten, J., Ryberg, M., Mellberg, C., Andersson, T., Chorell, E., Lindahl, B., Larsson, C., Holst, Jens Juul & Olsson, T., 2019, In: European Journal of Endocrinology. 180, 6, p. 417-427

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The liver-alpha-cell axis after a mixed meal and during weight loss in type 2 diabetes

    Otten, J., Stomby, A., Waling, M., Chorell, E., Ryberg, M., Svensson, M., Holst, Jens Juul & Olsson, T., 2021, In: Endocrine Connections. 10, 9, p. 1101-1110

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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