Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- Published
Reduced incretin effect precedes diabetes development following duodenopancreatectomy in individuals without diabetes
Di Giuseppe, G., Soldovieri, L., Ciccarelli, G., Ferraro, P. M., Quero, G., Cinti, F., Capece, U., Moffa, S., Nista, E. C., Gasbarrini, A., Mari, A., Alfieri, S., Tondolo, V., Pontecorvi, A., Holst, Jens Juul, Giaccari, A. & Mezza, T., 2024, In: Journal of Clinical Investigation. 134, 8, 3 p., e175133.Research output: Contribution to journal › Comment/debate › Research
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Fortifying a meal with oyster mushroom powder beneficially affects postprandial glucagon-like peptide-1, non-esterified free fatty acids and hunger sensation in adults with impaired glucose tolerance: a double-blind randomized controlled crossover trial
Dicks, L., Jakobs, L., Sari, M., Hambitzer, R., Ludwig, N., Simon, M., Stehle, P., Stoffel-Wagner, B., Helfrich, H., Ahlborn, J., Rühl, M., Hartmann, Bolette, Holst, Jens Juul & Ellinger, S., 2022, In: European Journal of Nutrition. 61, p. 687–701Research output: Contribution to journal › Journal article › Research › peer-review
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Fast pouch emptying, delayed small intestinal transit, and exaggerated gut hormone responses after Roux-en-Y gastric bypass
Dirksen, C., Damgaard, Morten, Bojsen-Møller, K. N., Jørgensen, N. B., Kielgast, U., Jacobsen, S. H., Naver, L. S., Worm, Dorte, Holst, Jens Juul, Madsbad, Sten, Hansen, D. L. & Madsen, J. L., Apr 2013, In: Neurogastroenterology and Motility. 25, 4, p. 346-e255 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass
Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Jacobsen, S. H., Clausen, T. R., Worm, Dorte, Hartmann, Bolette, Rehfeld, Jens Frederik, Damgaard, Morten, Madsen, J. L., Madsbad, Sten, Holst, Jens Juul & Hansen, D. L., 19 Feb 2013, In: International Journal of Obesity. 37, p. 1452-1459 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass
Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Jacobsen, S. H., Hansen, D. L., Worm, Dorte, Holst, Jens Juul & Madsbad, Sten, 2012, In: Diabetologia. 55, 7, p. 1890-901 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Energy intake, gastrointestinal transit, and gut hormone release in response to oral triglycerides and fatty acids in men with and without severe obesity
Dirksen, C., Graff, J., Fuglsang, S., Rehfeld, Jens Frederik, Holst, Jens Juul & Madsen, J. L., 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 3, p. G332-G337Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion: a case report
Dirksen, C., Hansen, D. L., Madsbad, Sten, Hvolris, L. E., Naver, L. S., Holst, Jens Juul & Worm, Dorte, 2010, In: Diabetes Care. 33, 2, p. 375-377Research output: Contribution to journal › Journal article › Research › peer-review
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Exaggerated release and preserved insulinotropic action of glucagon-like peptide-1 underlie insulin hypersecretion in glucose-tolerant individuals after Roux-en-Y gastric bypass
Dirksen, C., Bojsen-Møller, K. N., Jørgensen, N. B., Jacobsen, S. H., Kristiansen, V. B., Naver, L. S., Hansen, D. L., Worm, Dorte, Holst, Jens Juul & Madsbad, Sten, 2013, In: Diabetologia. 56, 12, p. 2679-2687Research output: Contribution to journal › Journal article › Research › peer-review
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Reduction in cardiovascular risk factors and insulin dose, but no beta-cell regeneration 1 year after Roux-en-Y gastric bypass in an obese patient with type 1 diabetes: a case report
Dirksen, C., Jacobsen, S. H., Bojsen-Møller, K. N., Jørgensen, N. B., Naver, L. S., Hvolris, L. E., Worm, Dorte, Madsbad, Sten, Holst, Jens Juul & Hansen, D. L., 7 Dec 2013, In: Obesity Research & Clinical Practice. 7, 4, p. e269-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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No Islet Cell Hyperfunction, but Altered Gut-Islet Regulation and Postprandial Hypoglycemia in Glucose-Tolerant Patients 3 Years After Gastric Bypass Surgery
Dirksen, C., Eiken, A., Bojsen-Møller, K. N., Svane, M. S., Martinussen, C., Jørgensen, N. B., Holst, Jens Juul & Madsbad, Sten, Sep 2016, In: Obesity Surgery. 26, 9, p. 2263-7 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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Feast or famine - are GLP-1 and ghrelin secretion intertwined?
Djurhuus, C. B., Hansen, T. K., Holst, Jens Juul & Schmitz, O., Jul 2002, In: Hormone and Metabolic Research. Supplement. 34, 7, p. 353-4 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating levels of ghrelin and GLP-1 are inversely related during glucose ingestion
Djurhuus, C. B., Hansen, T. K., Gravholt, C., Ørskov, L., Hosoda, H., Kangawa, K., Jørgensen, J. O. L., Holst, Jens Juul & Schmitz, O., Jul 2002, In: Hormone and Metabolic Research. Supplement. 34, 7, p. 411-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of Nicotinamide Riboside on Endocrine Pancreatic Function and Incretin Hormones in Nondiabetic Men With Obesity
Dollerup, O. L., Trammell, Sam, Hartmann, Bolette, Holst, Jens Juul, Christensen, B., Møller, N., Gillum, M. P., Treebak, Jonas Thue & Jessen, N., 1 Nov 2019, In: The Journal of clinical endocrinology and metabolism. 104, 11, p. 5703-5714 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Discovery, characterization, and clinical development of the glucagon-like peptides
Drucker, D. J., Habener, J. F. & Holst, Jens Juul, 1 Dec 2017, In: The Journal of Clinical Investigation. 127, 12, p. 4217-4227 11 p.Research output: Contribution to journal › Review › Research › peer-review
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The expanding incretin universe: from basic biology to clinical translation
Drucker, D. J. & Holst, Jens Juul, 2023, In: Diabetologia. 66, p. 1765-1779Research output: Contribution to journal › Review › Research › peer-review
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Comparison of the effects on insulin resistance and glucose tolerance of 6-mo high-monosaturated-fat, low-fat, and control diets
Due, A. P., Larsen, T. M., Hermansen, K., Stender, Steen, Holst, Jens Juul, Toubro, S., Martinussen, Torben & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 4, p. 855-862 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of the effects on insulin resistance and glucose tolerance of 6-mo high-monounsaturated-fat, low-fat, and control diets
Due, A. P., Larsen, T. M., Hermansen, K., Stender, Steen, Holst, Jens Juul, Toubro, S., Martinussen, Torben & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 4, p. 855-862 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Atrial natriuretic peptide-like immunoreactive material (ANP-L1) is released from the adrenal gland by splanchnic nerve stimulation
Duntas, L., Bornstein, S. R., Scherbaum, W. & Holst, Jens Juul, 1994, In: Exp.Clin.Endocrinol.. 101, p. 371-373Research output: Contribution to journal › Journal article › Research › peer-review
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Meal-induced compositional changes in blood and saliva in persons with bulimia nervosa
Dynesen, A. W., Jensen, A. B., Astrup, A., Petersson, B., Holst, Jens Juul & Nauntofte, B., 2008, In: American Journal of Clinical Nutrition. 87, 1, p. 12-22 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 is a marker of systemic inflammation in patients treated with high-dose chemotherapy and autologous stem cell transplantation
Ebbesen, M. S., Kissow, Hannelouise, Hartmann, Bolette, Grell, Kathrine, Gørløv, J. S., Kielsen, K., Holst, Jens Juul & Muller, Klaus, 2019, In: Biology of Blood and Marrow Transplantation. 25, 6, p. 1085-1091 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-Like Peptide-1 Is Associated With Systemic Inflammation in Pediatric Patients Treated With Hematopoietic Stem Cell Transplantation
Sørum, Maria Ebbesen, Kissow, Hannelouise, Hartmann, Bolette, Kielsen, K., Sørensen, K., Stinson, Sara, Frithioff-Bojsoe, C., Fonvig, Cilius Esmann, Holm, Jens-Christian, Hansen, Torben, Holst, Jens Juul & Müller, K. G., 2021, In: Frontiers in Immunology. 12, 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucometabolic hormones and cardiovascular risk markers in antipsychotic-treated patients
Ebdrup, Bjørn, Knop, Filip Krag, Madsen, A., Mortensen, H. B., Søgaard, B., Holst, Jens Juul, Szecsi, P. B. & Lublin, H., Sep 2014, In: Journal of Clinical Psychiatry. 75, 9, p. e899-905 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis
Edholm, T., Degerblad, M., Grybäck, P., Hilsted, Linda, Holst, Jens Juul, Jacobsson, H., Efendic, S., Schmidt, P. T. & Hellström, P. M., 1 Nov 2010, In: Neurogastroenterology and Motility Online. 22, 11, p. 1191-200, e315 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Difference in postprandial GLP-1 response despite similar glucose kinetics after consumption of wheat breads with different particle size in healthy men
Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., 2017, In: European Journal of Nutrition. 56, 3, p. 1063-1076 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The structure of wheat bread influences the postprandial metabolic response in healthy men
Eelderink, C., Noort, M. W. J., Sozer, N., Koehorst, M., Holst, Jens Juul, Deacon, Carolyn F., Rehfeld, Jens Frederik, Poutanen, K., Vonk, R. J., Oudhuis, L. & Priebe, M. G., Oct 2015, In: Food & Function. 6, 10, p. 3236-48 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin
Egerod, Kristoffer Lihme, Engelstoft, M. S., Grunddal, Kaare Villum, Nøhr, M. K., Secher, A., Sakata, I., Pedersen, Jens, Windeløv, Johanne Agerlin, Füchtbauer, E., Olsen, Jørgen, Sundler, F., Christensen, Jan Pravsgaard, Wierup, N., Olsen, Jesper Velgaard, Holst, Jens Juul, Zigman, J. M., Poulsen, Steen Seier & Schwartz, Thue W., 1 Dec 2012, In: Endocrinology. 153, 12, p. 5782-95 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptional and Functional Characterization of the G Protein-Coupled Receptor Repertoire of Gastric Somatostatin Cells
Egerod, Kristoffer Lihme, Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Zhao, M., Barir-Jensen, D., Nygaard, E. B., Petersen, N., Holst, Jens Juul & Schwartz, Thue W., Nov 2015, In: Endocrinology. 156, 11, p. 3909-23 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sympathoadrenal regulation of adrenocortical steroidogenesis
Ehrhart-Bornstein, M., Bornstein, S. R., Gonzalez-Hernandez, J., Holst, Jens Juul, Watermann, M. R. & Scherbaum, W. A., 1995, In: Endocrine Research. 21, p. 13-24Research output: Contribution to journal › Journal article › Research › peer-review
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Sympathoadrenal regulation of adrenal androstenedione release
Ehrhart-Bornstein, M., Bornstein, S. R., Behling, H. G., Holst, Jens Juul, Strohmayer, H. G., Rasmussen, T. N., Scherbaum, W. A. & Adler, G., 1994, In: Neuroendocrinology. 59, p. 406-412Research output: Contribution to journal › Journal article › Research › peer-review
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Vasoactive intestinal peptide in the porcine adrenal gland
Ehrhart-Bornstein, M., Bornstein, S. R. & Holst, Jens Juul, 1991, In: Neuroendocrinology. 54, p. 623-628Research output: Contribution to journal › Journal article › Research › peer-review
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Bilio-enteric flow and plasma concentrations of bile acids after gastric bypass and sleeve gastrectomy
Eiken, A., Fuglsang, S., Eiken, M., Svane, M. S., Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hansen, S. H., Trammell, Sam, Svenningsen, J. S., Rehfeld, Jens Frederik, Bojsen-Møller, K. N., Jørgensen, N. B., Holst, Jens Juul, Madsbad, Sten, Madsen, J. L. & Dirkse, C., 2020, In: International Journal of Obesity. 44, p. 1872-1883Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of beta cell and incretin function in patients with MODY1 (HNF4A MODY) and MODY3 (HNF1A MODY) in a Swedish patient collection
Ekholm, E., Shaat, N. & Holst, Jens Juul, Oct 2012, In: Acta Diabetologica. 49, 5, p. 349-54 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion
El-Ouaghlidi, A., Rehring, E., Holst, Jens Juul, Schweizer, A., Foley, J., Holmes, D. & Nauck, M. A., Nov 2007, In: The Journal of clinical endocrinology and metabolism. 92, 11, p. 4165-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations
Ellrichmann, M., Kapelle, M., Ritter, P. R., Holst, Jens Juul, Herzig, K. H., Schmidt, W. E., Schmitz, F. & Meier, J. J., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 3995-3998 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations
Ellrichmann, M., Kapelle, M., Ritter, P. R., Holst, Jens Juul, Herzig, K., Schmidt, W. E., Schmitz, F. & Meier, J. J., Oct 2008, In: The Journal of clinical endocrinology and metabolism. 93, 10, p. 3995-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells
Elmelund, E., Galsgaard, Katrine Douglas, Johansen, C. D., Trammell, Sam, Billeschou, Anna, Winther-Sørensen, Marie, Dal, Jenna Elizabeth Hunt, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Grevengoed, Trisha Jean, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: iScience. 25, 11, 20 p., 105296.Research output: Contribution to journal › Journal article › Research › peer-review
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Intestinal nutrient absorption in newborn pigs in response to enteral nutrition or treatment with glucagon-like peptide 2
Elnif, J., Buddington, R. K., Petersen, Y. M., Hartmann, B., Holst, Jens Juul, Schmidt, M., Burrin, D. G. & Sangild, Per Torp, 2001, Ikke angivet. Lindberg, J. E., Ogle & B. (eds.). CABI Publishing, p. 37-39 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
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Inhibition of gastric emptying by acarbose is correlated with GLP-1 response and accompanied by CCK release
Enc, F. Y., Imeryuz, N., Akin, L. & Holst, Jens Juul, 2001, In: Am J Physiol-Gastr L. 281, p. G752-G763Research output: Contribution to journal › Journal article › Research › peer-review
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Common variants in the hERG (KCNH2) voltage-gated potassium channel are associated with altered fasting and glucose-stimulated plasma incretin and glucagon responses
pjx571, pjx571, Mahendran, Y., Jonsson, Anna Elisabet, Gjesing, A. P., Weeke, P. E., Jørgensen, M. E., Færch, K., Witte, D. R., Holst, Jens Juul, Jørgensen, T., Grarup, Niels, Pedersen, Oluf Borbye, drb459, drb459, Torekov, Signe Sørensen, Kanters, Jørgen K. & Hansen, Torben, 2018, In: B M C Genetics. 19, 1, p. 1-9 9 p., 15.Research output: Contribution to journal › Journal article › Research › peer-review
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Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB
pjx571, pjx571, Lundgren, Jens, Albrechtsen, Nicolai Jacob Wewer, Mahendran, Y., Iepsen, E. P. W., Finocchietto, P., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Obesity Science & Practice. 3, 4, p. 425-433 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels
pjx571, pjx571, Iepsen, E. P. W., Galijatovic, E. A. A., Mahendran, Y., Lundgren, J. R., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, Dec 2016, In: Metabolomics. 12, 12, p. 1-9 9 p., 181.Research output: Contribution to journal › Journal article › Research › peer-review
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Orlistat accelerates gastric emptying and attenuates GIP release in healthy subjects
Enç, F. Y., Ones, T., Akin, H. L., Dede, F., Turoglu, H. T., Ulfer, G., Bekiroglu, N., Haklar, G., Rehfeld, Jens Frederik, Holst, Jens Juul, Ulusoy, N. B. & Imeryüz, N., 2008, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 296, 3, p. G482-9Research output: Contribution to journal › Journal article › Research › peer-review
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Reduction of insulinotropic properties of GLP-1 and GIP after glucocorticoid-induced insulin resistance
Eriksen, M., Jensen, D. H., Tribler, S., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2015, In: Diabetologia. 58, 5, p. 920-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
The association of cardiometabolic, diet and lifestyle parameters with plasma glucagon-like peptide-1: An IMI DIRECT study
Eriksen, R., White, M. C., Dawed, A. Y., Perez, I. G., Posma, J. M., Haid, M., Sharma, S., Prehn, C., Thomas, L. E., Koivula, R. W., Bizzotto, R., Mari, A., Giordano, G. N., Pavo, I., Schwenk, J. M., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A., Mahajan, A. & 26 others, , 2024, (E-pub ahead of print) In: Journal of Clinical Endocrinology and Metabolism.Research output: Contribution to journal › Journal article › Research › peer-review
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Counterregulatory hormone and symptom responses to hypoglycaemia in people with type 1 diabetes, insulin-treated type 2 diabetes or without diabetes: the Hypo-RESOLVE hypoglycaemic clamp study
Fabricius, T. W., Verhulst, C. E. M., Kristensen, Peter Lommer, Holst, Jens Juul, Tack, C. J., McCrimmon, R. J., Heller, S. R., Evans, M. L., de Galan, B. E., Pedersen-Bjergaard, Ulrik & Hypo-RESOLVE Consortium, H. C., 2024, In: Acta Diabetologica. 61, 5, p. 623-633Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired fasting glycaemia vs impaired glucose tolerance: similar impairment of pancreatic alpha and beta cell function but differential roles of incretin hormones and insulin action
Faerch, K., Vaag, Allan, Holst, Jens Juul, Glümer, C., Pedersen, Oluf Borbye & Borch-Johnsen, K., 2008, In: Diabetologia. 51, 5, p. 853-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pathophysiology and aetiology of impaired fasting glycaemia and impaired glucose tolerance: does it matter for prevention and treatment of type 2 diabetes?
Faerch, K., Borch-Johnsen, K., Holst, Jens Juul & Vaag, Allan, 2009, In: Diabetologia. 52, 9, p. 1714-23 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Progression from normal glucose tolerance to impaired fasting glycaemia and impaired glucose tolerance: differential roles of insulin resistance and beta cell dysfunction
Faerch, K., Vaag, Allan, Holst, Jens Juul, Pedersen, O., Glumer, C. & Borch-Johnsen, K., 2008, In: Diabetologia. 51, Suppl. 1, p. S85-S86Research output: Contribution to journal › Journal article › Research › peer-review
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Determinants of glycemic charges in normoglycemic individuals
Faerch, K., Vaag, Allan, Holst, Jens Juul, Hansen, T., Glumer, C. & Borch-Johnsen, K., 2008, In: Diabetes. Suppl. 1, p. A659-A659 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Incretin and pancreatic hormone secretion in Caucasian non-diabetic carriers of the TCF7L2 rs7903146 risk T allele
Faerch, K., Pilgaard, K., Knop, Filip Krag, Hansen, Torben, Pedersen, Oluf Borbye, Jørgensen, T. & Holst, Jens Juul, 2012, In: Diabetes, Obesity and Metabolism Online. 15, 1, p. 91-95 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural history of insulin sensitivity and insulin secretion in the progression from normal glucose tolerance to impaired fasting glycemia and impaired glucose tolerance: the Inter99 study
Faerch, K., Vaag, Allan, Holst, Jens Juul, Hansen, Torben, Jørgensen, T. & Borch-Johnsen, K., 2008, In: Diabetes Care. 32, 3, p. 439-44 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin Resistance is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation
Faerch, K., Vistisen, D., Pacini, G., Torekov, Signe Sørensen, Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Ahrén, B. & Holst, Jens Juul, 8 Aug 2016, In: Diabetes. 65, 11, p. 3473-3481 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Actions of prolonged ghrelin infusion on gastrointestinal transit and glucose homeostasis in humans
Falkén, Y., Hellström, P. M., Sanger, G. J., Dewit, O., Dukes, G., Grybäck, P., Holst, Jens Juul & Näslund, E., 1 Jun 2010, In: Neurogastroenterology and Motility. 22, 6, p. e192-200Research output: Contribution to journal › Journal article › Research › peer-review
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Changes in Glucose Homeostasis after Roux-en-Y Gastric Bypass Surgery for Obesity at Day Three, Two Months, and One Year after Surgery: Role of Gut Peptides
Falkén, Y., Hellström, P. M., Holst, Jens Juul & Näslund, E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 7, p. 2227-35 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Gastrointestinal Hormones and β-Cell Function After Gastric Bypass and Sleeve Gastrectomy: A Randomized Controlled Trial (Oseberg)
Fatima, F., Hjelmesæth, J., Birkeland, K. I., Hanne, G. L., Hertel, J. K., Svanevik, M., Sandbu, R., Småstuen, M. C., Hartmann, Bolette, Holst, Jens Juul & Hofsø, D., 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 2, p. e756-e766 11 p., dgab643.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased expression of glucagon-like peptide-1 receptors in psoriasis plaques
Faurschou, A., Pedersen, Jens, Gyldenløve, M., Poulsen, Steen Seier, Holst, Jens Juul, Thyssen, Jacob Pontoppidan, Zachariae, Claus, Vilsbøll, Tina, Skov, Lone & Knop, Filip Krag, Feb 2013, In: Experimental Dermatology. 22, 2, p. 150-2 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo positron emission tomography imaging of decreased parasympathetic innervation in the gut of vagotomized patients
Fedorova, T. D., Knudsen, K., Hartmann, Bolette, Holst, Jens Juul, Mortensen, F. V., Krogh, K. & Borghammer, P., 2020, In: Neurogastroenterology and Motility. 32, 3, 8 p., 13759.Research output: Contribution to journal › Journal article › Research › peer-review
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Exenatide augments first and second phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes
Fehse, F., Trautmann, M., Holst, Jens Juul, Halseth, A. E., Nanyakkara, N., Nielsen, L., Fineman, M. S. D., Kim, D. D. & Nauck, M. A., 2005, In: J. Clin. Endocrinol. Metab.. 90, p. 5991-5997Research output: Contribution to journal › Journal article › Research
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Exenatide augments first- and second-phase insulin secretion in response to intravenous glucose in subjects with type 2 diabetes
Fehse, F., Trautmann, M., Holst, Jens Juul, Halseth, A. E., Nanayakkara, N., Nielsen, L. L., Fineman, M. S., Kim, D. D. & Nauck, M. A., Nov 2005, In: The Journal of clinical endocrinology and metabolism. 90, 11, p. 5991-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interdependency of EGF and GLP-2 Signaling in Attenuating Mucosal Atrophy in a Mouse Model of Parenteral Nutrition
Feng, Y., Demehri, F. R., Xiao, W., Tsai, Y., Jones, J. C., Brindley, C. D., Threadgill, D. W., Holst, Jens Juul, Hartmann, Bolette, Barrett, T. A., Teitelbaum, D. H. & Dempsey, P. J., May 2017, In: Cellular and Molecular Gastroenterology and Hepatology. 3, 3, p. 447-468 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Response to Comment on Færch et al. GLP-1 Response to Oral Glucose Is Reduced in Prediabetes, Screen-Detected Type 2 Diabetes, and Obesity and Influenced by Sex: The ADDITION-PRO Study. Diabetes 2015;64:2513–2525
Ferch, K., Torekov, Signe Sørensen, Vistisen, D., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Sandbek, A., Holst, Jens Juul & Jørgensen, M. E., 1 Sep 2015, In: Diabetes. 64, 9, p. e30-e31Research output: Contribution to journal › Comment/debate › Research › peer-review
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Individuals with type 2 diabetes have higher density of small intestinal neurotensin-expressing cells
Ferreira, F. P., Pereira, S. S., Costa, M. M., Guimarães, M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2023, In: Molecular and Cellular Biochemistry. 478, 12, p. 2779-2787Research output: Contribution to journal › Journal article › Research › peer-review
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Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8
Fieseler, P., Bridenbaugh, S., Nustede, R., Martell, J., Nauck, M. A., Ørskov, Cathrine & Holst, Jens Juul, 1995, In: Am. J. Physiol.. Vol 268, p. E949-E955Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pituitary adenylate-cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans.
Filipson, K., Tornøe, K., Holst, Jens Juul & Ahrén, B., 1997, In: J. Clin. Endocrinol. Metab.. 82, p. 3093-3098Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PACAP contributes to insulin secretion after gastric glucose gavage in mice
Filipsson, K., Holst, Jens Juul & Ahrén, B., 2000, In: Am. J. Physiol.. 279, p. R424-432Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of glucagon-like peptide-1 on energy expenditure and substrate metabolism in humans
Flint, A., Raben, A., Rehfeld, J. F., Holst, Jens Juul & Astrup, A., 2000, In: International Journal of Obesity. 24, p. 288-298Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 promotes satiety and suppresses energy intake in humans
Flint, A., Raben, A., Holst, Jens Juul & Astrup, A., 1997, International journal of obesity. 21 ed. European Association for the Study of Obesity, p. 16 1 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
Flint, A., Raben, Anne, Astrup, A. & Holst, Jens Juul, 1998, In: Journal of Clinical Investigation. 101, 3, p. 515-520 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 suppresses energy expenditure in obese humans
Flint, A., Raben, A., Holst, Jens Juul & Astrup, A., 1999, International journal of obesity. Després, J-P. & Macdonald, I. (eds.). 23 ed. European Association for the Study of Obesity, p. S35 1 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
The ¤use of glycaemic index tables to predict glycaemic index of composite breakfast meals
Flint, A., Møller, B. K., Raben, Anne, Pedersen, D., Tetens, I., Holst, Jens Juul & Astrup, A., 2004, In: British Journal of Nutrition. 91, 6, p. 979-989 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The use of glycaemic index tables to predict glycaemic index of breakfast meals
Flint, A., Møller, B. K., Raben, Anne, Tetens, Inge , Holst, Jens Juul & Astrup, A., 2005, In: British Journal of Nutrition. 94, 1, p. 135-136 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Glycemic and insulinemic responses as determinants of appetite in humans
Flint, A., Møller, B. K., Raben, Anne, Sloth, B., Pedersen, D., Tetens, Inge , Holst, Jens Juul & Astrup, A., 2006, In: American Journal of Clinical Nutrition. 84, 6, p. 1365-1373 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of a glucagon-like peptide-1 receptor agonist on glucose tolerance in women with previous gestational diabetes mellitus: protocol for an investigator-initiated, randomised, placebo-controlled, double-blinded, parallel intervention trial
Foghsgaard, S., Vedtofte, L., Mathiesen, Elisabeth, Svare, J. A., Gluud, Lise Lotte, Holst, Jens Juul, Damm, Peter, Knop, Filip Krag & Vilsbøll, T., 2013, In: B M J Open. 3, 10, p. 1-8 9 p., e003834.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference
Foghsgaard, S., Andreasen, C., Vedtofte, L., Andersen, E. S., Bahne, E., Strandberg, C., Buhl, T., Holst, Jens Juul, Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, Jan 2017, In: Diabetes Care. 40, 1, p. 109-116 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide treatment for the prevention of glucose tolerance deterioration in women with prior gestational diabetes mellitus: A 52-week randomized controlled clinical trial
Foghsgaard, S., Vedtofte, L., Andersen, E. S., Bahne, E., Andreasen, C., Sørensen, A. L., Forman, Julie Lyng, Mathiesen, Elisabeth, Svare, J. A., Clausen, Tine Dalsgaard, Damm, Peter, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 26, 1, p. 201-214 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect
Foghsgaard, S., Vedtofte, L., Andreasen, C., Andersen, E. S., Bahne, E., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Knop, Filip Krag & Vilsbøll, Tina, Jul 2017, In: Diabetologia. 60, 7, p. 1344-1353 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes
Foley, J. E., Ligueros-Saylan, M., He, Y., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., Oct 2008, In: Hormone and Metabolic Research. Supplement. 40, 10, p. 727-30 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Vildagliptin on Glucagon Concentration During Meals in Patients with Type 1 Diabetes
Foley, J. E., Ligueros-Saylan, M., He, Y. L., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., 2008, In: Hormone and Metabolic Research. 40, 10, p. 727-730 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combinatorial, additive and dose-dependent drug–microbiome associations
Forslund, S. K., Chakaroun, R., Zimmermann-Kogadeeva, M., Markó, L., Aron-Wisnewsky, J., Nielsen, T., Moitinho-Silva, L., Schmidt, T. S. B., Falony, G., Vieira-Silva, S., Adriouch, S., Alves, R. J., Assmann, K., Bastard, J. P., Birkner, T., Caesar, R., Chilloux, J., Coelho, L. P., Fezeu, L., Galleron, N. & 23 others, , 2021, In: Nature. 600, p. 500-517 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating Levels of the Soluble Receptor for AGE (sRAGE) during Escalating Oral Glucose Dosages and Corresponding Isoglycaemic i.v. Glucose Infusions in Individuals with and without Type 2 Diabetes
Fotheringham, A. K., Bagger, J. I., Borg, D. J., McCarthy, D. A., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Forbes, J. M., 2020, In: Nutrients. 12, 10, 12 p., 2928.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twelve-Week Treatment With Liraglutide as Add-on to Insulin in Normal-Weight Patients With Poorly Controlled Type 1 Diabetes: A Randomized, Placebo-Controlled, Double-Blind Parallel Study
Frandsen, C. S., Dejgaard, T. F., Holst, Jens Juul, Andersen, H. U., Thorsteinsson, B. & Madsbad, Sten, Dec 2015, In: Diabetes Care. 38, 12, p. 2250-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Non-insulin pharmacological therapies for treating type 1 diabetes
Frandsen, C. S., Dejgaard, T. F., Madsbad, Sten & Holst, Jens Juul, 2018, In: Expert Opinion on Pharmacotherapy. 19, 9, p. 947-960Research output: Contribution to journal › Review › Research › peer-review
- Published
Liraglutide as adjunct to insulin treatment in type 1 diabetes does not interfere with glycaemic recovery or gastric emptying rate during hypoglycaemia: a randomised, placebo-controlled, double-blind, parallel-group study
Frandsen, C. S., Dejgaard, T. F., Andersen, H. U., Holst, Jens Juul, Hartmann, Bolette, Thorsteinsson, B. & Madsbad, Sten, 17 Mar 2017, In: Diabetes, Obesity and Metabolism. 19, 6, p. 773-782 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extreme duration exercise affects old and younger men differently
Frandsen, J., Sahl, R. E., Rømer, T., Thunestvedt Hansen, M., Nielsen, A. B., Lie-Olesen, M. M., Rasmusen, H. K., Søgaard, D., Ingersen, A., Rosenkilde, M., Westerterp, K., Holst, J. J., Andersen, J. L., Markowski, A. R., Blachnio-Zabielska, A., Clemmensen, C., Sacchetti, M., Cataldo, A., Traina, M., Larsen, S. & 2 others, , 2022, In: Acta Physiologica. 235, 3, e13816.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes
Fredheim, S., Andersen, M. M., Pörksen, S., Nielsen, L. B., Pipper, C., Hansen, L., Holst, Jens Juul, Thomsen, J., Johannesen, Jesper, Mortensen, H. B. & Svensson, Jannet, 2015, In: Diabetologia. 58, 4, p. 828-34 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of whey on blood glucose and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects.
Frid, A. H., Nilsson, M., Holst, Jens Juul & Björck, I. M. E., 2005, In: American Journal of Clinical Nutrition. 82, 1, p. 69-75 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Attenuated processing of proglucagon and glucagon-like peptide- 1 in carboxypeptidase E-deficient mice
Friis-Hansen, L., Lacourse, K. A., Samuelson, L. C. & Holst, Jens Juul, 2001, In: J. Endocrinol.. 169, p. 595-602Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adult glucose metabolism in extremely birthweight-discordant monozygotic twins
Frost, M., Petersen, I., Brixen, K., Beck-Nielsen, H., Holst, Jens Juul, Christiansen, L., Højlund, K. & Christensen, K., Dec 2012, In: Diabetologia. 55, 12, p. 3204-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of liraglutide on ectopic fat in polycystic ovary syndrome: A randomized clinical trial
Frøssing, S., Nylander, M., Chabanova, E., Frystyk, J., Holst, Jens Juul, Kistorp, Caroline Michaela Nervil, Skouby, Sven O. & Faber, Jens, Jan 2018, In: Diabetes, Obesity and Metabolism. 20, 1, p. 215-218Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of whey protein and dietary fiber intake on insulin sensitivity, body composition, energy expenditure, blood pressure, and appetite in subjects with abdominal obesity
Fuglsang-Nielsen, R., Rakvaag, E., Langdahl, B., Knudsen, K. E. B., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K. & Gregersen, S., 2021, In: European Journal of Clinical Nutrition. 75, p. 611–619Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Consumption of nutrients and insulin resistance suppress markers of bone turnover in subjects with abdominal obesity
Fuglsang-Nielsen, R., Rakvaag, E., Vestergaard, P., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K., Gregersen, S. & Starup-Linde, J., 2020, In: Bone. 133, 9 p., 115230.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.
Furuta, M., Yano, H., Zhou, A., Rouille, Y., Holst, Jens Juul, Carroll, R., Ravazzolla, M., Orci, L. & Steiner, D. F., 1997, In: Proc. Natl. Acad. Sci.. 94, p. 6646-6651Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-Like Peptide-1 (GLP-1) Response to Oral Glucose is Reduced in Pre-diabetes, Screen-detected Type 2 Diabetes and Obesity, and Influenced by Sex: The ADDITION-PRO Study
Færch, K., Torekov, Signe Sørensen, Vistisen, D., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Sandbæk, A., Holst, Jens Juul & Jørgensen, M. E., Jul 2015, In: Diabetes. 64, p. 2513-25 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of angiotensin II receptor blockade on cerebral, cardiovascular, counter-regulatory, and symptomatic responses during hypoglycaemia in patients with type 1 diabetes
Færch, L. H., Thorsteinsson, B., Tarnow, L., Holst, Jens Juul, Kjær, T. W., Kanters, Jørgen K., Larroude, C., Dela, Flemming & Pedersen-Bjergaard, Ulrik, Dec 2015, In: Journal of the Renin-Angiotensin-Aldosterone System. 16, 4, p. 1036-1045 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment
Gabe, M. B. N., Skov-Jeppesen, Kirsa, Gasbjerg, Lærke Smidt, Schiellerup, S. P., Martinussen, C., Gadgaard, S., Boer, G. A., Oeke, J., Pedersen, Lola Julie Torz, Veedfald, Simon, Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: Pharmacological Research. 176, 106058.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice
Gabe, M. B. N., Christensen, Liv von Voss, Dal, Jenna Elizabeth Hunt, Gadgaard, S., Gasbjerg, Lærke Smidt, Holst, Jens Juul, Kissow, Hannelouise, Hartmann, Bolette & Rosenkilde, Mette, Jan 2023, In: British Journal of Pharmacology. 180, 13, p. 1674-1689Research output: Contribution to journal › Journal article › Research › peer-review
- Published
N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction
Gabe, M. B. N., Gasbjerg, Lærke Smidt, Gadgaard, S., Lindquist, Peter, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4473-4485Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel agonist- and antagonist-based radioligands for the GLP-2 receptor - useful tools for studies of basic GLP-2R pharmacology
Gadgaard, S., van der Velden, W. J. C., Schiellerup, S. P., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Boer, G. A., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: British Journal of Pharmacology. 179, 9, p. 1998-2015Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system
Gadgaard, S., Windeløv, Johanne Agerlin, Schiellerup, S. P., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2023, In: Biomedicine and Pharmacotherapy. 160, 13 p., 114383.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon promotes hepatic autophagy by AMPK-mediated mTORC1 inhibition
Galsgaard, Katrine Douglas, Lee, J., Hubbard, B. T., Zhang, X. -., Cline, G. W., Nasiri, A. R., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Pertersen, K. F. & Shulman, G. I., 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S232Research output: Contribution to journal › Conference abstract in journal › Research
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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