The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria

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  • Torsten Zuberbier
  • Amir Hamzah Abdul Latiff
  • Mohamed Abuzakouk
  • Susan Aquilina
  • Riccardo Asero
  • Diane Baker
  • Barbara Ballmer-Weber
  • Christine Bangert
  • Moshe Ben-Shoshan
  • Jonathan A. Bernstein
  • Carsten Bindslev-Jensen
  • Knut Brockow
  • Zenon Brzoza
  • Herberto Jose Chong Neto
  • Martin K. Church
  • Paulo R. Criado
  • Inna V. Danilycheva
  • Corinna Dressler
  • Luis Felipe Ensina
  • Luz Fonacier
  • Matthew Gaskins
  • Krisztian Gáspár
  • Aslı Gelincik
  • Ana Giménez-Arnau
  • Kiran Godse
  • Margarida Gonçalo
  • Clive Grattan
  • Martine Grosber
  • Eckard Hamelmann
  • Jacques Hébert
  • Michihiro Hide
  • Allen Kaplan
  • Alexander Kapp
  • Aharon Kessel
  • Emek Kocatürk
  • Kanokvalai Kulthanan
  • Désirée Larenas-Linnemann
  • Antti Lauerma
  • Tabi A. Leslie
  • Markus Magerl
  • Michael Makris
  • Raisa Y. Meshkova
  • Martin Metz
  • Daniel Micallef
  • Charlotte G. Mortz
  • Alexander Nast
  • Hanneke Oude-Elberink
  • Ruby Pawankar
  • Paolo D. Pigatto
  • Hector Ratti Sisa
  • María Isabel Rojo Gutiérrez
  • Sarbjit S. Saini
  • Peter Schmid-Grendelmeier
  • Bulent E. Sekerel
  • Frank Siebenhaar
  • Hanna Siiskonen
  • Angele Soria
  • Petra Staubach-Renz
  • Luca Stingeni
  • Gordon Sussman
  • Andrea Szegedi
  • Zahava Vadasz
  • Christian Vestergaard
  • Bettina Wedi
  • Zuotao Zhao
  • Marcus Maurer

This update and revision of the international guideline for urticaria was developed following the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is a joint initiative of the Dermatology Section of the European Academy of Allergology and Clinical Immunology (EAACI), the Global Allergy and Asthma European Network (GA²LEN) and its Urticaria and Angioedema Centers of Reference and Excellence (UCAREs and ACAREs), the European Dermatology Forum (EDF; EuroGuiDerm), and the Asia Pacific Association of Allergy, Asthma and Clinical Immunology with the participation of 64 delegates of 50 national and international societies and from 31 countries. The consensus conference was held on 3 December 2020. This guideline was acknowledged and accepted by the European Union of Medical Specialists (UEMS). Urticaria is a frequent, mast cell–driven disease that presents with wheals, angioedema, or both. The lifetime prevalence for acute urticaria is approximately 20%. Chronic spontaneous or inducible urticaria is disabling, impairs quality of life, and affects performance at work and school. This updated version of the international guideline for urticaria covers the definition and classification of urticaria and outlines expert-guided and evidence-based diagnostic and therapeutic approaches for the different subtypes of urticaria.

OriginalsprogEngelsk
TidsskriftAllergy: European Journal of Allergy and Clinical Immunology
Vol/bind77
Udgave nummer3
Sider (fra-til)734-766
Antal sider33
ISSN0105-4538
DOI
StatusUdgivet - 2022

Bibliografisk note

Funding Information:
The guideline is a joint initiative of the Dermatology Section of the European Academy of Allergology and Clinical Immunology (EAACI), the Global Allergy and Asthma European Network (GA²LEN) and its Urticaria and Angioedema Centers of Reference and Excellence (UCAREs and ACAREs), the European Dermatology Forum (EDF), and the Asia Pacific Association of Allergy, Asthma, and Clinical Immunology (APAAACI). All of these organizations provided funding for the development of the guideline, which is an update and revision of the EAACI/GA²LEN/EDF/WAO guideline on urticaria published in 2018. There was no funding from other sources. 1–4

Funding Information:
The authors would like to thank the physicians and specialists who contributed to the development of this update of the guidelines through their active participation in the democratic process and discussion during the 6th International Consensus Meeting on Urticaria 2020. They would also like to thank the national societies for funding their delegates.

Publisher Copyright:
© 2021 GA²LEN. Allergy published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd.

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