ANP and BNP in atrial fibrillation before and after cardioversion--and their relationship to cardiac volume and function
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ANP and BNP in atrial fibrillation before and after cardioversion--and their relationship to cardiac volume and function. / Therkelsen, Susette Krohn; Groenning, Bjoern Aaris; Kjaer, Andreas; Svendsen, Jesper Hastrup; Boje Jensen, Gorm.
In: International Journal of Cardiology, Vol. 127, No. 3, 2007, p. 396-9.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - ANP and BNP in atrial fibrillation before and after cardioversion--and their relationship to cardiac volume and function
AU - Therkelsen, Susette Krohn
AU - Groenning, Bjoern Aaris
AU - Kjaer, Andreas
AU - Svendsen, Jesper Hastrup
AU - Boje Jensen, Gorm
N1 - Keywords: Atrial Fibrillation; Atrial Function; Atrial Natriuretic Factor; Cardiac Volume; Electric Countershock; Humans; Natriuretic Peptide, Brain; Time Factors; Ventricular Function
PY - 2007
Y1 - 2007
N2 - The role of atrial (ANP) and B-type (BNP) natriuretic peptide in atrial fibrillation (AF) is not clear. Our aim was to describe ANP and BNP in AF, and their changes following cardioversion in persistent AF. Furthermore, we wanted to assess the association between ANP and BNP and cardiac volume and function evaluated by magnetic resonance imaging. ANP and BNP decreased significantly following cardioversion. After 180 days of sinus rhythm, ANP and BNP were still significantly elevated. Same results were seen in patients with lone AF. Left and right atrial volumes correlated positively with ANP and BNP. Changes in left atrial volume were predictive of changes in ANP and BNP following cardioversion. AF may cause enduringly elevated ANP and BNP and atrial volume seems to be an important determinant of ANP and BNP in AF.
AB - The role of atrial (ANP) and B-type (BNP) natriuretic peptide in atrial fibrillation (AF) is not clear. Our aim was to describe ANP and BNP in AF, and their changes following cardioversion in persistent AF. Furthermore, we wanted to assess the association between ANP and BNP and cardiac volume and function evaluated by magnetic resonance imaging. ANP and BNP decreased significantly following cardioversion. After 180 days of sinus rhythm, ANP and BNP were still significantly elevated. Same results were seen in patients with lone AF. Left and right atrial volumes correlated positively with ANP and BNP. Changes in left atrial volume were predictive of changes in ANP and BNP following cardioversion. AF may cause enduringly elevated ANP and BNP and atrial volume seems to be an important determinant of ANP and BNP in AF.
U2 - 10.1016/j.ijcard.2007.04.059
DO - 10.1016/j.ijcard.2007.04.059
M3 - Journal article
C2 - 17628724
VL - 127
SP - 396
EP - 399
JO - International Journal of Cardiology
JF - International Journal of Cardiology
SN - 0167-5273
IS - 3
ER -
ID: 21258898